Organism Overview: Buchnera aphidicola


 
mnmG protein networkhttps://string-db.org/network/118110.XW81_00010Hypothetical protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs t [...]
atpB protein networkhttps://string-db.org/network/118110.XW81_00015ATP synthase F0F1 subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.
atpE protein networkhttps://string-db.org/network/118110.XW81_00020ATP F0F1 synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extr [...]
atpF protein networkhttps://string-db.org/network/118110.XW81_00025Hypothetical protein; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
atpH protein networkhttps://string-db.org/network/118110.XW81_00030Hypothetical protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembra [...]
atpA protein networkhttps://string-db.org/network/118110.XW81_00035ATP F0F1 synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
atpG protein networkhttps://string-db.org/network/118110.XW81_00040ATP F0F1 synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the [...]
atpD protein networkhttps://string-db.org/network/118110.XW81_00045ATP synthase F0F1 subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
atpC protein networkhttps://string-db.org/network/118110.XW81_00050Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane.
gyrB protein networkhttps://string-db.org/network/118110.XW81_00055DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
ANF16838.1 protein networkhttps://string-db.org/network/118110.XW81_00060Hypothetical protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) [...]
rpmH protein networkhttps://string-db.org/network/118110.XW81_0006550S ribosomal protein L34; In Escherichia coli transcription of this gene is enhanced by polyamines; Derived by automated computational analysis using gene prediction method: Protein Homology; Be [...]
rnpA protein networkhttps://string-db.org/network/118110.XW81_00070Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein compo [...]
ANF16841.1 protein networkhttps://string-db.org/network/118110.XW81_00075Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
yidC protein networkhttps://string-db.org/network/118110.XW81_00080Membrane protein insertase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins [...]
mnmE protein networkhttps://string-db.org/network/118110.XW81_00085tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
ANF16844.1 protein networkhttps://string-db.org/network/118110.XW81_00090Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
groES protein networkhttps://string-db.org/network/118110.XW81_00100Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
groEL protein networkhttps://string-db.org/network/118110.XW81_00105Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
ANF16847.1 protein networkhttps://string-db.org/network/118110.XW81_00110DNA replication protein DnaC; Acts to load the DnaB helicase onto the initiation site during DNA replication; Derived by automated computational analysis using gene prediction method: Protein Hom [...]
ANF16848.1 protein networkhttps://string-db.org/network/118110.XW81_00115Hypothetical protein; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.
ftsY protein networkhttps://string-db.org/network/118110.XW81_00120Hypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle [...]
rpoH protein networkhttps://string-db.org/network/118110.XW81_00125RNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involve [...]
glmS protein networkhttps://string-db.org/network/118110.XW81_00130Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
glmU protein networkhttps://string-db.org/network/118110.XW81_00135Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catal [...]
ANF16852.1 protein networkhttps://string-db.org/network/118110.XW81_00140Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
metE protein networkhttps://string-db.org/network/118110.XW81_001455-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; [...]
ANF16854.1 protein networkhttps://string-db.org/network/118110.XW81_00150Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
purH protein networkhttps://string-db.org/network/118110.XW81_00155Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF16856.1 protein networkhttps://string-db.org/network/118110.XW81_00160DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
rpoC protein networkhttps://string-db.org/network/118110.XW81_00165DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/118110.XW81_00170DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplL protein networkhttps://string-db.org/network/118110.XW81_0017550S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the ba [...]
rplJ protein networkhttps://string-db.org/network/118110.XW81_0018050S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal prot [...]
rplA protein networkhttps://string-db.org/network/118110.XW81_0018550S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/118110.XW81_0019050S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/118110.XW81_00195Transcription antiterminator NusG; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA poly [...]
secE protein networkhttps://string-db.org/network/118110.XW81_00200Hypothetical protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the Se [...]
murB protein networkhttps://string-db.org/network/118110.XW81_00230UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
metF protein networkhttps://string-db.org/network/118110.XW81_00235MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; Derived by automated computational analysis using gene prediction met [...]
argG protein networkhttps://string-db.org/network/118110.XW81_00240Argininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
argH protein networkhttps://string-db.org/network/118110.XW81_00245Argininosuccinate lyase; Catalyzes the formation of arginine from (N-L-arginino)succinate; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF16869.1 protein networkhttps://string-db.org/network/118110.XW81_00250Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
rpoD protein networkhttps://string-db.org/network/118110.XW81_00255RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the p [...]
dnaG protein networkhttps://string-db.org/network/118110.XW81_00260DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpsU protein networkhttps://string-db.org/network/118110.XW81_0026530S ribosomal protein S21; A small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; [...]
tsaD protein networkhttps://string-db.org/network/118110.XW81_00270Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer o [...]
ribB protein networkhttps://string-db.org/network/118110.XW81_002753,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
cca protein networkhttps://string-db.org/network/118110.XW81_00280tRNA CCA-pyrophosphorylase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order [...]
uppP protein networkhttps://string-db.org/network/118110.XW81_00285Hypothetical protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
ANF16877.1 protein networkhttps://string-db.org/network/118110.XW81_00290PTS system glucose-specific transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with the [...]
ANF16878.1 protein networkhttps://string-db.org/network/118110.XW81_00295Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate ac [...]
ANF16879.1 protein networkhttps://string-db.org/network/118110.XW81_00300PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
ligA protein networkhttps://string-db.org/network/118110.XW81_00305Hypothetical protein; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the en [...]
gltX protein networkhttps://string-db.org/network/118110.XW81_00320Hypothetical protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of t [...]
ANF16881.1 protein networkhttps://string-db.org/network/118110.XW81_00330Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
ANF16882.1 protein networkhttps://string-db.org/network/118110.XW81_00335Hypothetical protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
ANF16883.1 protein networkhttps://string-db.org/network/118110.XW81_00340Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF16884.1 protein networkhttps://string-db.org/network/118110.XW81_00345Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
fliI protein networkhttps://string-db.org/network/118110.XW81_00350ATP synthase; Involved in type III protein export during flagellum assembly; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF16886.1 protein networkhttps://string-db.org/network/118110.XW81_00355Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF16887.1 protein networkhttps://string-db.org/network/118110.XW81_00360Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
ANF16888.1 protein networkhttps://string-db.org/network/118110.XW81_00365Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
ANF16889.1 protein networkhttps://string-db.org/network/118110.XW81_00370Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF16890.1 protein networkhttps://string-db.org/network/118110.XW81_00375Hypothetical protein; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the [...]
ANF16891.1 protein networkhttps://string-db.org/network/118110.XW81_00380Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
fliP protein networkhttps://string-db.org/network/118110.XW81_00385Flagellar biosynthesis protein flip; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
fliQ protein networkhttps://string-db.org/network/118110.XW81_00390Hypothetical protein; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.
ANF16894.1 protein networkhttps://string-db.org/network/118110.XW81_00395Hypothetical protein; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.
rpmG protein networkhttps://string-db.org/network/118110.XW81_0040050S ribosomal protein L33; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL33 family.
rpmB protein networkhttps://string-db.org/network/118110.XW81_0040550S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL28 family.
ANF16897.1 protein networkhttps://string-db.org/network/118110.XW81_00410Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
ppa protein networkhttps://string-db.org/network/118110.XW81_00415Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
pmbA protein networkhttps://string-db.org/network/118110.XW81_00420Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using g [...]
rsmI protein networkhttps://string-db.org/network/118110.XW81_0042516S rRNA methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
tal protein networkhttps://string-db.org/network/118110.XW81_00435Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
ANF16902.1 protein networkhttps://string-db.org/network/118110.XW81_00440Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
dapE protein networkhttps://string-db.org/network/118110.XW81_00445Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in [...]
dapA protein networkhttps://string-db.org/network/118110.XW81_00450Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
aroC protein networkhttps://string-db.org/network/118110.XW81_00455Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
ANF16906.1 protein networkhttps://string-db.org/network/118110.XW81_00460Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
hisG protein networkhttps://string-db.org/network/118110.XW81_00465ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate [...]
hisD protein networkhttps://string-db.org/network/118110.XW81_00470Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
hisC protein networkhttps://string-db.org/network/118110.XW81_00475Histidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computationa [...]
hisB protein networkhttps://string-db.org/network/118110.XW81_00480Imidazoleglycerol-phosphate dehydratase; Catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol ph [...]
hisH protein networkhttps://string-db.org/network/118110.XW81_00485Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glu [...]
hisA protein networkhttps://string-db.org/network/118110.XW81_004901-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
hisF protein networkhttps://string-db.org/network/118110.XW81_00495Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and [...]
hisI protein networkhttps://string-db.org/network/118110.XW81_00500phosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylami [...]
ANF16915.1 protein networkhttps://string-db.org/network/118110.XW81_005056-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
metG protein networkhttps://string-db.org/network/118110.XW81_00515methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
tilS protein networkhttps://string-db.org/network/118110.XW81_00520Hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converte [...]
ANF16918.1 protein networkhttps://string-db.org/network/118110.XW81_00530Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF16919.1 protein networkhttps://string-db.org/network/118110.XW81_00535Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
rnfA protein networkhttps://string-db.org/network/118110.XW81_00540Electron transporter RsxA; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
rnfB protein networkhttps://string-db.org/network/118110.XW81_00545Electron transport complex protein RnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferred [...]
rnfD protein networkhttps://string-db.org/network/118110.XW81_00555Hypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.
rnfG protein networkhttps://string-db.org/network/118110.XW81_00560Hypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.
rnfE protein networkhttps://string-db.org/network/118110.XW81_00565Elongation factor G; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
nth protein networkhttps://string-db.org/network/118110.XW81_00570Hypothetical protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving th [...]
tyrS protein networkhttps://string-db.org/network/118110.XW81_00575tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
ANF16927.1 protein networkhttps://string-db.org/network/118110.XW81_00580Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family.
ANF16928.1 protein networkhttps://string-db.org/network/118110.XW81_00585YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; Derived by automated computational analysis using gene [...]
ANF16929.1 protein networkhttps://string-db.org/network/118110.XW81_00590Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
ANF17294.1 protein networkhttps://string-db.org/network/118110.XW81_00595Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate [...]
thrS protein networkhttps://string-db.org/network/118110.XW81_00600threonine--tRNA ligase; Catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adeny [...]
ANF16931.1 protein networkhttps://string-db.org/network/118110.XW81_00605Translation initiation factor IF-3; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IF-3 family.
rpmI protein networkhttps://string-db.org/network/118110.XW81_0061050S ribosomal protein L35; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL35 family.
rplT protein networkhttps://string-db.org/network/118110.XW81_0061550S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing func [...]
pheS protein networkhttps://string-db.org/network/118110.XW81_00620phenylalanyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthe [...]
pheT protein networkhttps://string-db.org/network/118110.XW81_00625Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily [...]
yajC protein networkhttps://string-db.org/network/118110.XW81_00630Preprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into memb [...]
glyS protein networkhttps://string-db.org/network/118110.XW81_00635Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
glyQ protein networkhttps://string-db.org/network/118110.XW81_00640Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
nfo protein networkhttps://string-db.org/network/118110.XW81_00645Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-p [...]
rplY protein networkhttps://string-db.org/network/118110.XW81_00650Hypothetical protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.
rsmA protein networkhttps://string-db.org/network/118110.XW81_0066016S rRNA methyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a crit [...]
apaH protein networkhttps://string-db.org/network/118110.XW81_00665Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
ANF16942.1 protein networkhttps://string-db.org/network/118110.XW81_00670Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
carB protein networkhttps://string-db.org/network/118110.XW81_00675Carbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for [...]
carA protein networkhttps://string-db.org/network/118110.XW81_00680Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed [...]
dapB protein networkhttps://string-db.org/network/118110.XW81_00685Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
ispH protein networkhttps://string-db.org/network/118110.XW81_006904-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethyl [...]
lspA protein networkhttps://string-db.org/network/118110.XW81_00695Hypothetical protein; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
ileS protein networkhttps://string-db.org/network/118110.XW81_00700isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such err [...]
rpsT protein networkhttps://string-db.org/network/118110.XW81_0071030S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
dnaJ protein networkhttps://string-db.org/network/118110.XW81_00715Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in a [...]
dnaK protein networkhttps://string-db.org/network/118110.XW81_00720Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
nuoA protein networkhttps://string-db.org/network/118110.XW81_00725NADH:ubiquinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the [...]
nuoB protein networkhttps://string-db.org/network/118110.XW81_00730NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this specie [...]
nuoC protein networkhttps://string-db.org/network/118110.XW81_00735NADH:ubiquinone oxidoreductase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in [...]
ANF17297.1 protein networkhttps://string-db.org/network/118110.XW81_00740NADH dehydrogenase; Catalyzes the transfer of electrons from NADH to quinone; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF16954.1 protein networkhttps://string-db.org/network/118110.XW81_00745NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
ANF16955.1 protein networkhttps://string-db.org/network/118110.XW81_00750Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
nuoH protein networkhttps://string-db.org/network/118110.XW81_00755NADH:ubiquinone oxidoreductase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in [...]
nuoI protein networkhttps://string-db.org/network/118110.XW81_00760NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this specie [...]
ANF16958.1 protein networkhttps://string-db.org/network/118110.XW81_00765Hypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for eve [...]
nuoK protein networkhttps://string-db.org/network/118110.XW81_00770NADH:ubiquinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the [...]
ANF16960.1 protein networkhttps://string-db.org/network/118110.XW81_00775NADH:ubiquinone oxidoreductase subunit L; Catalyzes the transfer of electrons from NADH to ubiquinone; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF16961.1 protein networkhttps://string-db.org/network/118110.XW81_00780Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
nuoN protein networkhttps://string-db.org/network/118110.XW81_00785Hypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this spec [...]
ANF16963.1 protein networkhttps://string-db.org/network/118110.XW81_00790Hypothetical protein; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pt [...]
ANF16964.1 protein networkhttps://string-db.org/network/118110.XW81_00795Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
prs protein networkhttps://string-db.org/network/118110.XW81_00800Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hy [...]
prfA protein networkhttps://string-db.org/network/118110.XW81_00810Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
prmC protein networkhttps://string-db.org/network/118110.XW81_00815Hypothetical protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein [...]
ANF16968.1 protein networkhttps://string-db.org/network/118110.XW81_00820Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
nadE protein networkhttps://string-db.org/network/118110.XW81_00825NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
ANF16969.1 protein networkhttps://string-db.org/network/118110.XW81_00835Hypothetical protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
ANF16970.1 protein networkhttps://string-db.org/network/118110.XW81_00840Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF16971.1 protein networkhttps://string-db.org/network/118110.XW81_00845Ribonucleotide-diphosphate reductase subunit beta; B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodime [...]
ANF16972.1 protein networkhttps://string-db.org/network/118110.XW81_00850Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
gyrA protein networkhttps://string-db.org/network/118110.XW81_00855DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
ANF16975.1 protein networkhttps://string-db.org/network/118110.XW81_00865Peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
ung protein networkhttps://string-db.org/network/118110.XW81_00870uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
grpE protein networkhttps://string-db.org/network/118110.XW81_00875Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the [...]
ppnK protein networkhttps://string-db.org/network/118110.XW81_00880Inorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylatio [...]
ANF16979.1 protein networkhttps://string-db.org/network/118110.XW81_00885Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaredoxin family. Monothiol subfamily.
rnt protein networkhttps://string-db.org/network/118110.XW81_00890Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP [...]
ANF16981.1 protein networkhttps://string-db.org/network/118110.XW81_00895Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
pth protein networkhttps://string-db.org/network/118110.XW81_00900Hypothetical protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
ANF16983.1 protein networkhttps://string-db.org/network/118110.XW81_00905Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF16984.1 protein networkhttps://string-db.org/network/118110.XW81_00910Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
thrB protein networkhttps://string-db.org/network/118110.XW81_00915Serine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
thrA protein networkhttps://string-db.org/network/118110.XW81_00920Aspartate kinase; Multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; [...]
dksA protein networkhttps://string-db.org/network/118110.XW81_00925RNA polymerase-binding transcription factor; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regu [...]
truA protein networkhttps://string-db.org/network/118110.XW81_00930tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
ANF16988.1 protein networkhttps://string-db.org/network/118110.XW81_00935Penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain ( [...]
secA protein networkhttps://string-db.org/network/118110.XW81_00940Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to [...]
coaE protein networkhttps://string-db.org/network/118110.XW81_00945Hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
guaC protein networkhttps://string-db.org/network/118110.XW81_00950Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivative [...]
aceE protein networkhttps://string-db.org/network/118110.XW81_00955Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
ANF16993.1 protein networkhttps://string-db.org/network/118110.XW81_00960Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF16994.1 protein networkhttps://string-db.org/network/118110.XW81_00965E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction meth [...]
ANF16995.1 protein networkhttps://string-db.org/network/118110.XW81_00970Hypothetical protein; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thio [...]
ANF16996.1 protein networkhttps://string-db.org/network/118110.XW81_00975Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family.
ftsZ protein networkhttps://string-db.org/network/118110.XW81_00980Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...]
ftsA protein networkhttps://string-db.org/network/118110.XW81_00985Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
ANF16999.1 protein networkhttps://string-db.org/network/118110.XW81_00990Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ddl protein networkhttps://string-db.org/network/118110.XW81_00995D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
murC protein networkhttps://string-db.org/network/118110.XW81_01000UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
ftsW protein networkhttps://string-db.org/network/118110.XW81_01010Flippase; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
murD protein networkhttps://string-db.org/network/118110.XW81_01015UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the Mur [...]
ANF17301.1 protein networkhttps://string-db.org/network/118110.XW81_01040Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
rsmH protein networkhttps://string-db.org/network/118110.XW81_0104516S rRNA methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
ilvH protein networkhttps://string-db.org/network/118110.XW81_01050Acetolactate synthase 3 regulatory subunit; With IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produ [...]
ilvI protein networkhttps://string-db.org/network/118110.XW81_01055Acetolactate synthase 3 catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; Derived by automated computational analysis using gene prediction method: Pr [...]
ANF17303.1 protein networkhttps://string-db.org/network/118110.XW81_01060Hypothetical protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belon [...]
ANF17005.1 protein networkhttps://string-db.org/network/118110.XW81_01065Serine endoprotease; Protease Do; required at high temperature; degrades damaged proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to t [...]
dapD protein networkhttps://string-db.org/network/118110.XW81_010702,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthe [...]
map protein networkhttps://string-db.org/network/118110.XW81_01075Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharg [...]
rpsB protein networkhttps://string-db.org/network/118110.XW81_0108030S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family.
tsf protein networkhttps://string-db.org/network/118110.XW81_01085Hypothetical protein; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the [...]
pyrH protein networkhttps://string-db.org/network/118110.XW81_01090Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
frr protein networkhttps://string-db.org/network/118110.XW81_01095Hypothetical protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes fro [...]
dxr protein networkhttps://string-db.org/network/118110.XW81_011001-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).
uppS protein networkhttps://string-db.org/network/118110.XW81_01105UDP pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-und [...]
dnaE protein networkhttps://string-db.org/network/118110.XW81_01115DNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; Derived by automated computati [...]
proS protein networkhttps://string-db.org/network/118110.XW81_01120proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA( [...]
flhB protein networkhttps://string-db.org/network/118110.XW81_01125Hypothetical protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belo [...]
flhA protein networkhttps://string-db.org/network/118110.XW81_01130Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs [...]
argS protein networkhttps://string-db.org/network/118110.XW81_01135arginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
gloB protein networkhttps://string-db.org/network/118110.XW81_01155Hypothetical protein; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
rnhA protein networkhttps://string-db.org/network/118110.XW81_01160Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
dnaQ protein networkhttps://string-db.org/network/118110.XW81_01165DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing funct [...]
gpt protein networkhttps://string-db.org/network/118110.XW81_01175Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
grpE-2 protein networkhttps://string-db.org/network/118110.XW81_01180Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the [...]
ANF17022.1 protein networkhttps://string-db.org/network/118110.XW81_01185Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0125 (RnfH) family.
smpB protein networkhttps://string-db.org/network/118110.XW81_01190Hypothetical protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
tadA protein networkhttps://string-db.org/network/118110.XW81_01195Hypothetical protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
acpS protein networkhttps://string-db.org/network/118110.XW81_012004'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
era protein networkhttps://string-db.org/network/118110.XW81_01205Hypothetical protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also i [...]
rnc protein networkhttps://string-db.org/network/118110.XW81_01210Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some m [...]
lepA protein networkhttps://string-db.org/network/118110.XW81_01220Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon bac [...]
mnmA protein networkhttps://string-db.org/network/118110.XW81_01225tRNA 2-thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s [...]
hflD protein networkhttps://string-db.org/network/118110.XW81_01230Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17030.1 protein networkhttps://string-db.org/network/118110.XW81_01235Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automate [...]
ANF17031.1 protein networkhttps://string-db.org/network/118110.XW81_01245enoyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
rnb protein networkhttps://string-db.org/network/118110.XW81_01250Exoribonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
ANF17033.1 protein networkhttps://string-db.org/network/118110.XW81_01255Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
lipB protein networkhttps://string-db.org/network/118110.XW81_01260Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also ac [...]
lipA protein networkhttps://string-db.org/network/118110.XW81_01265Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, there [...]
pyrF protein networkhttps://string-db.org/network/118110.XW81_01270Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamil [...]
ribA protein networkhttps://string-db.org/network/118110.XW81_01275GTP cyclohydrolase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
cls protein networkhttps://string-db.org/network/118110.XW81_01280Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
ANF17039.1 protein networkhttps://string-db.org/network/118110.XW81_01285acyl-CoA esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17040.1 protein networkhttps://string-db.org/network/118110.XW81_01290Hypothetical protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
ANF17041.1 protein networkhttps://string-db.org/network/118110.XW81_01295Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
trpA protein networkhttps://string-db.org/network/118110.XW81_01300Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
trpB protein networkhttps://string-db.org/network/118110.XW81_01305Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpC protein networkhttps://string-db.org/network/118110.XW81_01310Indole-3-glycerol phosphate synthase; Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the Tr [...]
trpD protein networkhttps://string-db.org/network/118110.XW81_01315Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranila [...]
ANF17307.1 protein networkhttps://string-db.org/network/118110.XW81_01320Multidrug DMT transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
sohB protein networkhttps://string-db.org/network/118110.XW81_01325Peptidase; Multicopy suppressor of htrA(degP); Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17047.1 protein networkhttps://string-db.org/network/118110.XW81_01330Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the inositol monophosphatase superfamily.
rlmN protein networkhttps://string-db.org/network/118110.XW81_01335Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial [...]
ispG protein networkhttps://string-db.org/network/118110.XW81_013404-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG fa [...]
hisS protein networkhttps://string-db.org/network/118110.XW81_01345histidine--tRNA ligase; Catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adeny [...]
glyA protein networkhttps://string-db.org/network/118110.XW81_01350Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
bioB protein networkhttps://string-db.org/network/118110.XW81_01360Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily [...]
bioA protein networkhttps://string-db.org/network/118110.XW81_01365Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8 [...]
ANF17054.1 protein networkhttps://string-db.org/network/118110.XW81_01370Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17055.1 protein networkhttps://string-db.org/network/118110.XW81_01375Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase famil [...]
ANF17056.1 protein networkhttps://string-db.org/network/118110.XW81_01380Hypothetical protein; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
ANF17057.1 protein networkhttps://string-db.org/network/118110.XW81_01385Deoxyribodipyrimidine photolyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA photolyase family.
ANF17058.1 protein networkhttps://string-db.org/network/118110.XW81_01390Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17059.1 protein networkhttps://string-db.org/network/118110.XW81_01395Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17060.1 protein networkhttps://string-db.org/network/118110.XW81_01400Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2 [...]
pal protein networkhttps://string-db.org/network/118110.XW81_01405Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
gpmA protein networkhttps://string-db.org/network/118110.XW81_01410Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
pfkA protein networkhttps://string-db.org/network/118110.XW81_014156-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
ANF17308.1 protein networkhttps://string-db.org/network/118110.XW81_01420Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family.
tpiA protein networkhttps://string-db.org/network/118110.XW81_01425Hypothetical protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the trio [...]
rpsA protein networkhttps://string-db.org/network/118110.XW81_0143030S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
cmk protein networkhttps://string-db.org/network/118110.XW81_01435Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
aroA protein networkhttps://string-db.org/network/118110.XW81_014403-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
serC protein networkhttps://string-db.org/network/118110.XW81_014453-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phos [...]
serS protein networkhttps://string-db.org/network/118110.XW81_01450seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
ANF17070.1 protein networkhttps://string-db.org/network/118110.XW81_01455Thioredoxin reductase; Catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; Derived by automated computational analysis using gene prediction method: Protein Homolog [...]
infA protein networkhttps://string-db.org/network/118110.XW81_01460Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
aspS protein networkhttps://string-db.org/network/118110.XW81_01465aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor [...]
znuB protein networkhttps://string-db.org/network/118110.XW81_01470High-affinity zinc transporter membrane component; Involved in transport of zinc(II) with ZnuA and C; Derived by automated computational analysis using gene prediction method: Protein Homology.
znuC protein networkhttps://string-db.org/network/118110.XW81_01475Zinc ABC transporter ATPase; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamil [...]
ANF17075.1 protein networkhttps://string-db.org/network/118110.XW81_01485Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
zwf protein networkhttps://string-db.org/network/118110.XW81_01490Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
htpX protein networkhttps://string-db.org/network/118110.XW81_01495Heat shock protein HtpX; Metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M48B family.
ANF17077.1 protein networkhttps://string-db.org/network/118110.XW81_01500Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
ANF17078.1 protein networkhttps://string-db.org/network/118110.XW81_01505Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17079.1 protein networkhttps://string-db.org/network/118110.XW81_01510Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
minE protein networkhttps://string-db.org/network/118110.XW81_01515Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensu [...]
ANF17081.1 protein networkhttps://string-db.org/network/118110.XW81_01520ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; Derived by automated computational analysis using gene prediction method: Protein Homology.
minC protein networkhttps://string-db.org/network/118110.XW81_01525Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have for [...]
murJ protein networkhttps://string-db.org/network/118110.XW81_01545Membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
pyrC protein networkhttps://string-db.org/network/118110.XW81_01550Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
ANF17085.1 protein networkhttps://string-db.org/network/118110.XW81_01555Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17086.1 protein networkhttps://string-db.org/network/118110.XW81_01560Hypothetical protein; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
flgC protein networkhttps://string-db.org/network/118110.XW81_01565With FlgF and B makes up the proximal portion of the flagellar basal body rod; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17088.1 protein networkhttps://string-db.org/network/118110.XW81_01570Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the flagella basal body rod proteins family.
flgG protein networkhttps://string-db.org/network/118110.XW81_01575Makes up the distal portion of the flagellar basal body rod; Derived by automated computational analysis using gene prediction method: Protein Homology.
flgH protein networkhttps://string-db.org/network/118110.XW81_01580Hypothetical protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
flgI protein networkhttps://string-db.org/network/118110.XW81_01585Flagellar basal body P-ring biosynthesis protein FlgA; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
ANF17091.1 protein networkhttps://string-db.org/network/118110.XW81_01590Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17311.1 protein networkhttps://string-db.org/network/118110.XW81_01595Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17092.1 protein networkhttps://string-db.org/network/118110.XW81_01600Hypothetical protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
rpmF protein networkhttps://string-db.org/network/118110.XW81_0160550S ribosomal protein L32; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL32 family.
ANF17094.1 protein networkhttps://string-db.org/network/118110.XW81_01610Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17095.1 protein networkhttps://string-db.org/network/118110.XW81_01615Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
acpP protein networkhttps://string-db.org/network/118110.XW81_01620Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
tmk protein networkhttps://string-db.org/network/118110.XW81_01625Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
ANF17098.1 protein networkhttps://string-db.org/network/118110.XW81_01630Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17099.1 protein networkhttps://string-db.org/network/118110.XW81_01635DNAse; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17100.1 protein networkhttps://string-db.org/network/118110.XW81_01640PTS glucose-specific subunit IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation a [...]
ANF17101.1 protein networkhttps://string-db.org/network/118110.XW81_01645Purine nucleoside phosphoramidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
asnS protein networkhttps://string-db.org/network/118110.XW81_01650asparaginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
pyrD protein networkhttps://string-db.org/network/118110.XW81_01660Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
ANF17104.1 protein networkhttps://string-db.org/network/118110.XW81_01665Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17105.1 protein networkhttps://string-db.org/network/118110.XW81_01670Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0176 family.
valS protein networkhttps://string-db.org/network/118110.XW81_01675valyl-tRNA synthase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, [...]
pepA protein networkhttps://string-db.org/network/118110.XW81_01680Multifunctional aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various [...]
ANF17108.1 protein networkhttps://string-db.org/network/118110.XW81_01685Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
pyrI protein networkhttps://string-db.org/network/118110.XW81_01695Aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
ANF17110.1 protein networkhttps://string-db.org/network/118110.XW81_01700RutC family protein BU371; Derived by automated computational analysis using gene prediction method: Protein Homology.
deaD protein networkhttps://string-db.org/network/118110.XW81_01705Hypothetical protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
pnp protein networkhttps://string-db.org/network/118110.XW81_01710Hypothetical protein; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
rpsO protein networkhttps://string-db.org/network/118110.XW81_0171530S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
truB protein networkhttps://string-db.org/network/118110.XW81_01720tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
rbfA protein networkhttps://string-db.org/network/118110.XW81_01725Hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not wi [...]
infB protein networkhttps://string-db.org/network/118110.XW81_01730Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
nusA protein networkhttps://string-db.org/network/118110.XW81_01735Transcription elongation factor NusA; Participates in both transcription termination and antitermination.
glmM protein networkhttps://string-db.org/network/118110.XW81_01750Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
hflB protein networkhttps://string-db.org/network/118110.XW81_01755ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane prote [...]
rlmE protein networkhttps://string-db.org/network/118110.XW81_01760Hypothetical protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
greA protein networkhttps://string-db.org/network/118110.XW81_01765Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...]
ANF17120.1 protein networkhttps://string-db.org/network/118110.XW81_01770Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family.
murA protein networkhttps://string-db.org/network/118110.XW81_01775UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
rplU protein networkhttps://string-db.org/network/118110.XW81_0178050S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
rpmA protein networkhttps://string-db.org/network/118110.XW81_0178550S ribosomal protein L27; Involved in the peptidyltransferase reaction during translation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to [...]
obg protein networkhttps://string-db.org/network/118110.XW81_01790GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in contr [...]
rpsI protein networkhttps://string-db.org/network/118110.XW81_0179530S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family.
rplM protein networkhttps://string-db.org/network/118110.XW81_0180050S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages [...]
ANF17127.1 protein networkhttps://string-db.org/network/118110.XW81_01805Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ffh protein networkhttps://string-db.org/network/118110.XW81_01810Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain [...]
rpsP protein networkhttps://string-db.org/network/118110.XW81_0181530S ribosomal protein S16; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS16 family.
rimM protein networkhttps://string-db.org/network/118110.XW81_01820Hypothetical protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential [...]
trmD protein networkhttps://string-db.org/network/118110.XW81_01825tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
ANF17315.1 protein networkhttps://string-db.org/network/118110.XW81_0183050S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
tldD protein networkhttps://string-db.org/network/118110.XW81_01835Protease TldD; Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades [...]
aroQ protein networkhttps://string-db.org/network/118110.XW81_018403-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
rluD protein networkhttps://string-db.org/network/118110.XW81_0184523S rRNA pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
alaS protein networkhttps://string-db.org/network/118110.XW81_01850alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
csrA protein networkhttps://string-db.org/network/118110.XW81_01855Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid g [...]
gshA protein networkhttps://string-db.org/network/118110.XW81_01870Glutamate--cysteine ligase; Involved in the first step of glutathione biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glut [...]
ANF17137.1 protein networkhttps://string-db.org/network/118110.XW81_01875DNA-specific endonuclease I; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17138.1 protein networkhttps://string-db.org/network/118110.XW81_01880Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
ANF17139.1 protein networkhttps://string-db.org/network/118110.XW81_01885Hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of th [...]
rpiA protein networkhttps://string-db.org/network/118110.XW81_01890Hypothetical protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
ANF17141.1 protein networkhttps://string-db.org/network/118110.XW81_01910glutamate--tRNA ligase; Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adeny [...]
pyrG protein networkhttps://string-db.org/network/118110.XW81_01915CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the [...]
eno protein networkhttps://string-db.org/network/118110.XW81_01920Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
ispF protein networkhttps://string-db.org/network/118110.XW81_019252-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid [...]
ispD protein networkhttps://string-db.org/network/118110.XW81_019302-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to [...]
ftsB protein networkhttps://string-db.org/network/118110.XW81_01935Hypothetical protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, whic [...]
ANF17146.1 protein networkhttps://string-db.org/network/118110.XW81_01940DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA.
ANF17147.1 protein networkhttps://string-db.org/network/118110.XW81_01945Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.
ANF17148.1 protein networkhttps://string-db.org/network/118110.XW81_01950Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
engB protein networkhttps://string-db.org/network/118110.XW81_01955Hypothetical protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase fa [...]
ANF17150.1 protein networkhttps://string-db.org/network/118110.XW81_01960GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology.
gmk protein networkhttps://string-db.org/network/118110.XW81_01965Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
thyA protein networkhttps://string-db.org/network/118110.XW81_01970Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate ( [...]
lgt protein networkhttps://string-db.org/network/118110.XW81_01975Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
lysA protein networkhttps://string-db.org/network/118110.XW81_01980Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
lysS protein networkhttps://string-db.org/network/118110.XW81_01985lysine--tRNA ligase; Class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the ami [...]
prfB protein networkhttps://string-db.org/network/118110.XW81_01990Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
ANF17157.1 protein networkhttps://string-db.org/network/118110.XW81_01995Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family.
miaB protein networkhttps://string-db.org/network/118110.XW81_02000(dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine ( [...]
ANF17159.1 protein networkhttps://string-db.org/network/118110.XW81_02010Magnesium/cobalt efflux protein CorC; Involved in the transport of magnesium and cobalt ions; Derived by automated computational analysis using gene prediction method: Protein Homology.
leuS protein networkhttps://string-db.org/network/118110.XW81_02015leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the [...]
ANF17161.1 protein networkhttps://string-db.org/network/118110.XW81_02020Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
tusA protein networkhttps://string-db.org/network/118110.XW81_02030Hypothetical protein; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified [...]
ANF17163.1 protein networkhttps://string-db.org/network/118110.XW81_02035Aspartate-semialdehyde dehydrogenase; Catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; Derived by automated computational analysis using gene prediction method: Prot [...]
pgk protein networkhttps://string-db.org/network/118110.XW81_02045Phosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family.
ANF17166.1 protein networkhttps://string-db.org/network/118110.XW81_02050Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphat [...]
ANF17167.1 protein networkhttps://string-db.org/network/118110.XW81_02055Mechanosensitive ion channel protein MscS; Participates in the regulation of osmotic pressure changes within the cel; Derived by automated computational analysis using gene prediction method: Pro [...]
ANF17168.1 protein networkhttps://string-db.org/network/118110.XW81_02060Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
ANF17169.1 protein networkhttps://string-db.org/network/118110.XW81_02065Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
recB protein networkhttps://string-db.org/network/118110.XW81_02070Hypothetical protein; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectio [...]
ANF17171.1 protein networkhttps://string-db.org/network/118110.XW81_02085Murein transglycosylase; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
ribH protein networkhttps://string-db.org/network/118110.XW81_020906,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. [...]
thiL protein networkhttps://string-db.org/network/118110.XW81_02095Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thi [...]
ribD protein networkhttps://string-db.org/network/118110.XW81_021005-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; I [...]
nusB protein networkhttps://string-db.org/network/118110.XW81_02105Hypothetical protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal [...]
dxs protein networkhttps://string-db.org/network/118110.XW81_021101-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (D [...]
ANF17177.1 protein networkhttps://string-db.org/network/118110.XW81_02115Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family.
ANF17178.1 protein networkhttps://string-db.org/network/118110.XW81_02120Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
cyoE protein networkhttps://string-db.org/network/118110.XW81_02130Hypothetical protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
ANF17180.1 protein networkhttps://string-db.org/network/118110.XW81_02135Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17317.1 protein networkhttps://string-db.org/network/118110.XW81_02140Cytochrome o ubiquinol oxidase subunit III; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17181.1 protein networkhttps://string-db.org/network/118110.XW81_02145Cytochrome o ubiquinol oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heme-copper respiratory oxidase family.
ANF17318.1 protein networkhttps://string-db.org/network/118110.XW81_02150Cytochrome o ubiquinol oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17182.1 protein networkhttps://string-db.org/network/118110.XW81_02155Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family.
ANF17183.1 protein networkhttps://string-db.org/network/118110.XW81_02160Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
clpP protein networkhttps://string-db.org/network/118110.XW81_02165Hypothetical protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [...]
clpX protein networkhttps://string-db.org/network/118110.XW81_02170Hypothetical protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
lon protein networkhttps://string-db.org/network/118110.XW81_02175DNA-binding protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellul [...]
ANF17187.1 protein networkhttps://string-db.org/network/118110.XW81_02180Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17188.1 protein networkhttps://string-db.org/network/118110.XW81_02185Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17189.1 protein networkhttps://string-db.org/network/118110.XW81_02190Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
dnaX protein networkhttps://string-db.org/network/118110.XW81_02195DNA polymerase III subunit gamma; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exon [...]
ANF17191.1 protein networkhttps://string-db.org/network/118110.XW81_02200Nucleoid-associated protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
htpG protein networkhttps://string-db.org/network/118110.XW81_02205Heat shock protein 90; Molecular chaperone. Has ATPase activity.
adk protein networkhttps://string-db.org/network/118110.XW81_02210Hypothetical protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metab [...]
folD protein networkhttps://string-db.org/network/118110.XW81_02220Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10 [...]
cysS protein networkhttps://string-db.org/network/118110.XW81_02225cysteine--tRNA ligase; Catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; Derived by [...]
ANF17196.1 protein networkhttps://string-db.org/network/118110.XW81_02230Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0250 family.
ANF17197.1 protein networkhttps://string-db.org/network/118110.XW81_02235Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
aroE protein networkhttps://string-db.org/network/118110.XW81_02255Hypothetical protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimat [...]
tsaC protein networkhttps://string-db.org/network/118110.XW81_02260tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginnin [...]
def protein networkhttps://string-db.org/network/118110.XW81_02265Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
fmt protein networkhttps://string-db.org/network/118110.XW81_02270Hypothetical protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by [...]
rplQ protein networkhttps://string-db.org/network/118110.XW81_0227550S ribosomal protein L17; Derived by automated computational analysis using gene prediction method: Protein Homology.
rpoA protein networkhttps://string-db.org/network/118110.XW81_02280DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpsD protein networkhttps://string-db.org/network/118110.XW81_0228530S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpsK protein networkhttps://string-db.org/network/118110.XW81_0229030S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
rpsM protein networkhttps://string-db.org/network/118110.XW81_0229530S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 [...]
rpmJ protein networkhttps://string-db.org/network/118110.XW81_0230050S ribosomal protein L36; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL36 family.
secY protein networkhttps://string-db.org/network/118110.XW81_02305Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at t [...]
rplO protein networkhttps://string-db.org/network/118110.XW81_0231050S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
rpmD protein networkhttps://string-db.org/network/118110.XW81_0231550S ribosomal protein L30; L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; Derived by automated computational analysis using gene prediction method: Protein [...]
rpsE protein networkhttps://string-db.org/network/118110.XW81_0232030S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 fam [...]
rplR protein networkhttps://string-db.org/network/118110.XW81_0232550S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protubera [...]
ANF17210.1 protein networkhttps://string-db.org/network/118110.XW81_0233050S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the t [...]
rpsH protein networkhttps://string-db.org/network/118110.XW81_0233530S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to [...]
rpsN protein networkhttps://string-db.org/network/118110.XW81_0234030S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the un [...]
rplE protein networkhttps://string-db.org/network/118110.XW81_0234550S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [...]
rplX protein networkhttps://string-db.org/network/118110.XW81_0235050S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplN protein networkhttps://string-db.org/network/118110.XW81_0235550S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rpsQ protein networkhttps://string-db.org/network/118110.XW81_0236030S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rpmC protein networkhttps://string-db.org/network/118110.XW81_0236550S ribosomal protein L29; One of the stabilizing components for the large ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
rplP protein networkhttps://string-db.org/network/118110.XW81_0237050S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpsC protein networkhttps://string-db.org/network/118110.XW81_0237530S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplV protein networkhttps://string-db.org/network/118110.XW81_0238050S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wal [...]
rpsS protein networkhttps://string-db.org/network/118110.XW81_0238530S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplB protein networkhttps://string-db.org/network/118110.XW81_0239050S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rplW protein networkhttps://string-db.org/network/118110.XW81_0239550S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main dock [...]
rplD protein networkhttps://string-db.org/network/118110.XW81_0240050S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
rplC protein networkhttps://string-db.org/network/118110.XW81_0240550S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rpsJ protein networkhttps://string-db.org/network/118110.XW81_0241030S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
tuf protein networkhttps://string-db.org/network/118110.XW81_02415Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
fusA protein networkhttps://string-db.org/network/118110.XW81_02420Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- [...]
rpsG protein networkhttps://string-db.org/network/118110.XW81_0242530S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit inte [...]
rpsL protein networkhttps://string-db.org/network/118110.XW81_0243030S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S an [...]
ANF17231.1 protein networkhttps://string-db.org/network/118110.XW81_02435Sulfur transfer complex subunit TusB; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
ANF17232.1 protein networkhttps://string-db.org/network/118110.XW81_02440Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DsrF/TusC family.
ANF17233.1 protein networkhttps://string-db.org/network/118110.XW81_02445Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17322.1 protein networkhttps://string-db.org/network/118110.XW81_02450Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17234.1 protein networkhttps://string-db.org/network/118110.XW81_02455Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
trpS protein networkhttps://string-db.org/network/118110.XW81_02460Hypothetical protein; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
ANF17236.1 protein networkhttps://string-db.org/network/118110.XW81_02465Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.
aroB protein networkhttps://string-db.org/network/118110.XW81_024703-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
aroK protein networkhttps://string-db.org/network/118110.XW81_02475Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
deoD protein networkhttps://string-db.org/network/118110.XW81_02485Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
deoB protein networkhttps://string-db.org/network/118110.XW81_02490Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
nfuA protein networkhttps://string-db.org/network/118110.XW81_02495Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S protei [...]
bioH protein networkhttps://string-db.org/network/118110.XW81_02500Hypothetical protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid [...]
ANF17243.1 protein networkhttps://string-db.org/network/118110.XW81_02505Hypothetical protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA [...]
ANF17244.1 protein networkhttps://string-db.org/network/118110.XW81_02510Hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs [...]
ANF17245.1 protein networkhttps://string-db.org/network/118110.XW81_02515DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, a [...]
gshB protein networkhttps://string-db.org/network/118110.XW81_02520Catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; Derived by automated computati [...]
ANF17247.1 protein networkhttps://string-db.org/network/118110.XW81_02525Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
yqgF protein networkhttps://string-db.org/network/118110.XW81_02530Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
ANF17249.1 protein networkhttps://string-db.org/network/118110.XW81_025352-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isoprop [...]
leuD protein networkhttps://string-db.org/network/118110.XW81_02540Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily [...]
leuC protein networkhttps://string-db.org/network/118110.XW81_02545Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
leuB protein networkhttps://string-db.org/network/118110.XW81_025503-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-met [...]
trmB protein networkhttps://string-db.org/network/118110.XW81_02555Hypothetical protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
ANF17323.1 protein networkhttps://string-db.org/network/118110.XW81_02565Hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
murI protein networkhttps://string-db.org/network/118110.XW81_02570Hypothetical protein; Provides the (R)-glutamate required for cell wall biosynthesis.
ANF17254.1 protein networkhttps://string-db.org/network/118110.XW81_02575Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
pyrE protein networkhttps://string-db.org/network/118110.XW81_02590Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
dut protein networkhttps://string-db.org/network/118110.XW81_02595Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intrace [...]
rplI protein networkhttps://string-db.org/network/118110.XW81_02600Hypothetical protein; Binds to the 23S rRNA.
rpsR protein networkhttps://string-db.org/network/118110.XW81_0260530S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosom [...]
rpsF protein networkhttps://string-db.org/network/118110.XW81_0261030S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
purA protein networkhttps://string-db.org/network/118110.XW81_02615Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
ANF17261.1 protein networkhttps://string-db.org/network/118110.XW81_02620Cell division protein FtsH; HflC and HflK could regulate a protease.
ANF17262.1 protein networkhttps://string-db.org/network/118110.XW81_02625Cell division protein FtsH; HflC and HflK could encode or regulate a protease.
miaA protein networkhttps://string-db.org/network/118110.XW81_02630Hypothetical protein; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylall [...]
mtlD protein networkhttps://string-db.org/network/118110.XW81_02640Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17264.1 protein networkhttps://string-db.org/network/118110.XW81_02645PTS system mannitol-specific transporter subunit IICBA; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; subunit IIC forms [...]
pgi protein networkhttps://string-db.org/network/118110.XW81_02650Glucose-6-phosphate isomerase; Functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate [...]
orn protein networkhttps://string-db.org/network/118110.XW81_02655Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
ANF17267.1 protein networkhttps://string-db.org/network/118110.XW81_02665Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
ANF17326.1 protein networkhttps://string-db.org/network/118110.XW81_02670Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
rpmE protein networkhttps://string-db.org/network/118110.XW81_0267550S ribosomal protein L31; Binds the 23S rRNA.
hslV protein networkhttps://string-db.org/network/118110.XW81_02685ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
hslU protein networkhttps://string-db.org/network/118110.XW81_02690ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by [...]
ANF17272.1 protein networkhttps://string-db.org/network/118110.XW81_02695Septal ring assembly protein ZapB; Interacts with FisZ and is necessary for Z-ring formation; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17273.1 protein networkhttps://string-db.org/network/118110.XW81_02700Anthranilate synthase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology.
trpE protein networkhttps://string-db.org/network/118110.XW81_02705Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first [...]
ANF17275.1 protein networkhttps://string-db.org/network/118110.XW81_02710ferredoxin-NADP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
coaD protein networkhttps://string-db.org/network/118110.XW81_02715Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD [...]
ANF17278.1 protein networkhttps://string-db.org/network/118110.XW81_02725Phosphate transporter PitA; Involved in the transport of inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17279.1 protein networkhttps://string-db.org/network/118110.XW81_02730Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
cyaY protein networkhttps://string-db.org/network/118110.XW81_02740Frataxin-like protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
rho protein networkhttps://string-db.org/network/118110.XW81_02760Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
trxA protein networkhttps://string-db.org/network/118110.XW81_02765Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.
ANF17283.1 protein networkhttps://string-db.org/network/118110.XW81_02770ATP-dependent DNA helicase Rep; Single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; Derived by automated computational analysis using gene [...]
ilvC protein networkhttps://string-db.org/network/118110.XW81_02775Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yie [...]
ilvD protein networkhttps://string-db.org/network/118110.XW81_02780Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analy [...]
iscS protein networkhttps://string-db.org/network/118110.XW81_02790Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental [...]
ANF17287.1 protein networkhttps://string-db.org/network/118110.XW81_02795Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clust [...]
hscB protein networkhttps://string-db.org/network/118110.XW81_02800Hypothetical protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
ANF17289.1 protein networkhttps://string-db.org/network/118110.XW81_02805Molecular chaperone HscA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heat shock protein 70 family.
ANF17290.1 protein networkhttps://string-db.org/network/118110.XW81_028102Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
ANF17291.1 protein networkhttps://string-db.org/network/118110.XW81_02820Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.