Organism Overview: Streptococcus pneumoniae


 
dnaA protein networkhttps://string-db.org/network/171101.spr0001DNA biosynthesis, initiation, binding protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically doubl [...]
dnaN protein networkhttps://string-db.org/network/171101.spr0002DNA biosynthesis; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) whic [...]
spr0003 protein networkhttps://string-db.org/network/171101.spr0003Hypothetical protein.
ychF protein networkhttps://string-db.org/network/171101.spr0004Conserved hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
pth protein networkhttps://string-db.org/network/171101.spr0005Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
mfd protein networkhttps://string-db.org/network/171101.spr0006Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated tr [...]
spr0007 protein networkhttps://string-db.org/network/171101.spr0007Conserved hypothetical protein.
spr0008 protein networkhttps://string-db.org/network/171101.spr0008Hypothetical protein.
spr0009 protein networkhttps://string-db.org/network/171101.spr0009Conserved hypothetical protein.
tilS protein networkhttps://string-db.org/network/171101.spr0010Conserved hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine i [...]
hgt protein networkhttps://string-db.org/network/171101.spr0011Hypoxanthine guanine phosphoribosyltransferase.
ftsH protein networkhttps://string-db.org/network/171101.spr0012Cell-division protein / general stress protein (class III heat-shock); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the qu [...]
comX1 protein networkhttps://string-db.org/network/171101.spr0013Competence-specific global transcription modulator; Putative sigma factor.
Transposase_A protein networkhttps://string-db.org/network/171101.spr0014Transposase.
spr0015 protein networkhttps://string-db.org/network/171101.spr0015Hypothetical protein.
Transposase_B protein networkhttps://string-db.org/network/171101.spr0016Transposase.
spr0017 protein networkhttps://string-db.org/network/171101.spr0017Degenerate transposase (orf2); SPR0017-0019 constitute an IS1167 element in which the orf1 and orf2 components are degenerate.
spr0018 protein networkhttps://string-db.org/network/171101.spr0018Degenerate transposase (orf2); SPR0017-0019 constitute an IS1167 element in which the orf1 and orf2 components are degenerate.
spr0019 protein networkhttps://string-db.org/network/171101.spr0019Degenerate transposase (orf1); SPR0017-0019 constitute an IS1167 element in which the orf1 and orf2 components are degenerate.
spr0020 protein networkhttps://string-db.org/network/171101.spr0020Hypothetical protein.
purA protein networkhttps://string-db.org/network/171101.spr0021Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
tadA protein networkhttps://string-db.org/network/171101.spr0022Conserved hypothetical protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
dut protein networkhttps://string-db.org/network/171101.spr0023Deoxyuridinetriphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration o [...]
spr0024 protein networkhttps://string-db.org/network/171101.spr0024Conserved hypothetical protein; Similar to phosphoglycerate mutase.
radA protein networkhttps://string-db.org/network/171101.spr0025DNA repair: sensitivity to gamma and UV radiation; Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks (By s [...]
spr0026 protein networkhttps://string-db.org/network/171101.spr0026Conserved hypothetical protein.
spr0027 protein networkhttps://string-db.org/network/171101.spr0027Hypothetical protein.
prsA protein networkhttps://string-db.org/network/171101.spr0028Phosphoribosylpyrophosphate synthase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1- [...]
spr0029 protein networkhttps://string-db.org/network/171101.spr0029Degenerate transposase (orf1).
spr0030 protein networkhttps://string-db.org/network/171101.spr0030Hypothetical protein.
spr0031 protein networkhttps://string-db.org/network/171101.spr0031Hypothetical protein.
polA protein networkhttps://string-db.org/network/171101.spr0032DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
spr0033 protein networkhttps://string-db.org/network/171101.spr0033Conserved hypothetical protein.
spr0034 protein networkhttps://string-db.org/network/171101.spr0034Conserved hypothetical protein.
aspC protein networkhttps://string-db.org/network/171101.spr0035Aspartate aminotransferase.
recO protein networkhttps://string-db.org/network/171101.spr0036Conserved hypothetical protein; Involved in DNA repair and RecF pathway recombination (By similarity). Plays no role in chromosomal or plasmid transformation but is required for resolution of chr [...]
plsX protein networkhttps://string-db.org/network/171101.spr0037Involved in fatty acid/phospholipid synthesis; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fat [...]
acpP protein networkhttps://string-db.org/network/171101.spr0038Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
spr0039 protein networkhttps://string-db.org/network/171101.spr0039Degenerate transposase (orf2).
thmA protein networkhttps://string-db.org/network/171101.spr0040Amphipathic pore-forming peptide precursor.
IS1167 protein networkhttps://string-db.org/network/171101.spr0041Transposase (orf2).
IS1167-2 protein networkhttps://string-db.org/network/171101.spr0042Transposase (orf1).
comA protein networkhttps://string-db.org/network/171101.spr0043Transport ATP-binding protein ComA; Required for induction of competence. Seems to transport the competence-stimulating peptide (CSP) (By similarity); Belongs to the ABC transporter superfamily. [...]
comB protein networkhttps://string-db.org/network/171101.spr0044Transport protein ComB; Required for induction of competence; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
purC protein networkhttps://string-db.org/network/171101.spr0045Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family.
purL protein networkhttps://string-db.org/network/171101.spr0046Phosphoribosylformylglycinamide synthetase.
purF protein networkhttps://string-db.org/network/171101.spr0047Amidophosphoribosyl transferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine [...]
purM protein networkhttps://string-db.org/network/171101.spr0048Phosphoribosylaminoimidazole synthetase.
purN protein networkhttps://string-db.org/network/171101.spr00495'-phosphoribosylglycinamide transformylase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formy [...]
vanZ protein networkhttps://string-db.org/network/171101.spr0050Teicoplanin resistance protein.
purH protein networkhttps://string-db.org/network/171101.spr0051Phosphoribosylaminoimidazolecarboxamide formyltransferase.
purD protein networkhttps://string-db.org/network/171101.spr0052Phosphoribosylglycinamide synthetase.
purE protein networkhttps://string-db.org/network/171101.spr0053Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
purK protein networkhttps://string-db.org/network/171101.spr0054Phosphoribosyl glucinamide formyltransferase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
spr0055 protein networkhttps://string-db.org/network/171101.spr0055Hypothetical protein.
purB protein networkhttps://string-db.org/network/171101.spr0056Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
strH protein networkhttps://string-db.org/network/171101.spr0057Beta-N-acetyl-hexosaminidase precursor.
spr0058 protein networkhttps://string-db.org/network/171101.spr0058Conserved hypothetical protein; Similar to transcriptional regulator (GntR family).
bgaC protein networkhttps://string-db.org/network/171101.spr0059Beta-galactosidase 3; Belongs to the glycosyl hydrolase 35 family.
PTS-EIIB protein networkhttps://string-db.org/network/171101.spr0060Phosphotransferase system sugar-specific EIIB component.
PTS-EIIC protein networkhttps://string-db.org/network/171101.spr0061Phosphotransferase system sugar-specific EIIC component.
PTS-EIID protein networkhttps://string-db.org/network/171101.spr0062Phosphotransferase system sugar-specific EIID component.
PTS-EII protein networkhttps://string-db.org/network/171101.spr0063Phosphotransferase system sugar-specific EII component.
agaS protein networkhttps://string-db.org/network/171101.spr0064Tagatose-6-phosphate ketose/aldose isomerase.
galM protein networkhttps://string-db.org/network/171101.spr0065Aldose-1-epimerase (mutarotase); Converts alpha-aldose to the beta-anomer.
spr0066 protein networkhttps://string-db.org/network/171101.spr0066Conserved hypothetical protein.
spr0067 protein networkhttps://string-db.org/network/171101.spr0067Conserved hypothetical protein.
spr0068 protein networkhttps://string-db.org/network/171101.spr0068Conserved hypothetical protein; Similar to uridine phosphorylase.
spr0069 protein networkhttps://string-db.org/network/171101.spr0069Hypothetical protein.
trkH protein networkhttps://string-db.org/network/171101.spr0070Trk transporter membrane-spanning protein - K+ transport.
trkA protein networkhttps://string-db.org/network/171101.spr0071Trk transporter NAD+ binding protein - K+ transport.
spr0072 protein networkhttps://string-db.org/network/171101.spr0072Conserved hypothetical protein.
spr0073 protein networkhttps://string-db.org/network/171101.spr0073Hypothetical protein.
spr0074 protein networkhttps://string-db.org/network/171101.spr0074Hypothetical protein.
spr0075 protein networkhttps://string-db.org/network/171101.spr0075Conserved hypothetical protein; Similar to cell wall-associated serine proteinase.
rr08 protein networkhttps://string-db.org/network/171101.spr0076Response regulator.
hk08 protein networkhttps://string-db.org/network/171101.spr0077Histidine kinase.
rpsD protein networkhttps://string-db.org/network/171101.spr007830S Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
Transposase_A-2 protein networkhttps://string-db.org/network/171101.spr0079Degenerative transposase.
spr0080 protein networkhttps://string-db.org/network/171101.spr0080Hypothetical protein.
ABC-MSP protein networkhttps://string-db.org/network/171101.spr0081ABC transporter membrane-spanning permease - sugar transport.
ABC-MSP-2 protein networkhttps://string-db.org/network/171101.spr0082ABC transporter membrane spanning permease - sugar transport.
ABC-SBP protein networkhttps://string-db.org/network/171101.spr0083ABC transporter solute binding protein - sugar transport.
spr0084 protein networkhttps://string-db.org/network/171101.spr0084Conserved hypothetical protein; Belongs to the UPF0176 family.
spr0085 protein networkhttps://string-db.org/network/171101.spr0085Hypothetical protein.
spr0086 protein networkhttps://string-db.org/network/171101.spr0086Hypothetical protein.
spr0087 protein networkhttps://string-db.org/network/171101.spr0087Hypothetical protein.
spr0088 protein networkhttps://string-db.org/network/171101.spr0088Hypothetical protein.
spr0089 protein networkhttps://string-db.org/network/171101.spr0089Conserved hypothetical protein.
spr0090 protein networkhttps://string-db.org/network/171101.spr0090Conserved hypothetical protein.
spr0091 protein networkhttps://string-db.org/network/171101.spr0091Conserved hypothetical protein; Putative sugar transferase related protein.
capD protein networkhttps://string-db.org/network/171101.spr0092CapD protein, required for the biosynthesis of type 1 capsular polysaccharide.
gph protein networkhttps://string-db.org/network/171101.spr0093Phosphoglycolate phosphatase.
sdaA protein networkhttps://string-db.org/network/171101.spr0094L-serine dehydratase alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.
sdaB protein networkhttps://string-db.org/network/171101.spr0095L-serine dehydratase beta subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.
spr0096 protein networkhttps://string-db.org/network/171101.spr0096Hypothetical protein.
spr0098 protein networkhttps://string-db.org/network/171101.spr0098Hypothetical protein.
ABC-MSP-3 protein networkhttps://string-db.org/network/171101.spr0099ABC transporter membrane-spanning permease - amino acid transport.
ABC-NBD protein networkhttps://string-db.org/network/171101.spr0100ABC transporter ATP-binding protein - amino acid transport.
ABC-SBP-2 protein networkhttps://string-db.org/network/171101.spr0101ABC transporter solute-binding protein - amino acid transport.
argG protein networkhttps://string-db.org/network/171101.spr0102Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
argH protein networkhttps://string-db.org/network/171101.spr0103Arginine succinate lyase.
spr0105 protein networkhttps://string-db.org/network/171101.spr0105Transporter, truncation.
spr0106 protein networkhttps://string-db.org/network/171101.spr0106Transporter, truncation; Similar to competence factor transporting ATP-binding/permease protein ComA.
spr0107 protein networkhttps://string-db.org/network/171101.spr0107Hypothetical protein.
spr0108 protein networkhttps://string-db.org/network/171101.spr0108Conserved hypothetical protein; Similar to ComB protein.
spr0109 protein networkhttps://string-db.org/network/171101.spr0109Hypothetical protein.
spr0111 protein networkhttps://string-db.org/network/171101.spr0111Hypothetical protein.
spr0112 protein networkhttps://string-db.org/network/171101.spr0112Hypothetical protein.
spr0113 protein networkhttps://string-db.org/network/171101.spr0113Hypothetical protein.
spr0114 protein networkhttps://string-db.org/network/171101.spr0114Hypothetical protein.
spr0115 protein networkhttps://string-db.org/network/171101.spr0115Hypothetical protein.
spr0116 protein networkhttps://string-db.org/network/171101.spr0116Hypothetical protein.
spr0117 protein networkhttps://string-db.org/network/171101.spr0117Hypothetical protein.
spr0118 protein networkhttps://string-db.org/network/171101.spr0118Hypothetical protein.
spr0119 protein networkhttps://string-db.org/network/171101.spr0119Hypothetical protein.
pspA protein networkhttps://string-db.org/network/171101.spr0121Surface protein pspA precursor.
trmU protein networkhttps://string-db.org/network/171101.spr0122tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
spr0123 protein networkhttps://string-db.org/network/171101.spr0123Conserved hypothetical protein; Similar to MutT protein.
gidA protein networkhttps://string-db.org/network/171101.spr0124Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s( [...]
rnj protein networkhttps://string-db.org/network/171101.spr0125Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
spr0126 protein networkhttps://string-db.org/network/171101.spr0126Conserved hypothetical protein; Belongs to the UPF0356 family.
orf51 protein networkhttps://string-db.org/network/171101.spr0127Orf51; Induced during competence.
spr0128 protein networkhttps://string-db.org/network/171101.spr0128Hypothetical protein.
spr0129 protein networkhttps://string-db.org/network/171101.spr0129Conserved hypothetical protein.
rimI protein networkhttps://string-db.org/network/171101.spr0130Ribosomal protein alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.
gcp protein networkhttps://string-db.org/network/171101.spr0131Secreted metalloendopeptidase Gcp; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in t [...]
spr0132 protein networkhttps://string-db.org/network/171101.spr0132Degenerate transposase (orf2).
spr0133 protein networkhttps://string-db.org/network/171101.spr0133Degenerate transposase (orf2).
spr0134 protein networkhttps://string-db.org/network/171101.spr0134Degenerative transposase.
epsG protein networkhttps://string-db.org/network/171101.spr0135Glycosyltransferase involved exopolysaccharide (EPS) synthesis.
spr0136 protein networkhttps://string-db.org/network/171101.spr0136Glycosyl transferase, family 2.
ABC-NP protein networkhttps://string-db.org/network/171101.spr0137ABC transporter ATP-binding/membrane spanning permease - possible multidrug resistance.
spr0138 protein networkhttps://string-db.org/network/171101.spr0138Hypothetical protein.
ugd protein networkhttps://string-db.org/network/171101.spr0139UDP-glucose dehydrogenase.
mutR protein networkhttps://string-db.org/network/171101.spr0140Positive transcriptional regulator of mutA.
spr0141 protein networkhttps://string-db.org/network/171101.spr0141Hypothetical protein.
spr0142 protein networkhttps://string-db.org/network/171101.spr0142Hypothetical protein.
spr0143 protein networkhttps://string-db.org/network/171101.spr0143Hypothetical protein.
spr0144 protein networkhttps://string-db.org/network/171101.spr0144Conserved hypothetical protein.
spr0145 protein networkhttps://string-db.org/network/171101.spr0145Hypothetical protein.
ABC-SBP-3 protein networkhttps://string-db.org/network/171101.spr0146ABC transporter substrate-binding protein - amino acid transport.
ABC-SBP-4 protein networkhttps://string-db.org/network/171101.spr0147ABC transporter solute-binding protein - unknown substrate; Belongs to the nlpA lipoprotein family.
dapE protein networkhttps://string-db.org/network/171101.spr0148Succinyl-diaminopimelic descuccinlyase (ArgE/DapE/Acy1 family protein).
ABC-NBD-2 protein networkhttps://string-db.org/network/171101.spr0149ABC transporter ATP-binding protein - unknown substrate; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
ABC-MSD protein networkhttps://string-db.org/network/171101.spr0150ABC transporter membrane-spanning permease - unknown substrate.
spr0151 protein networkhttps://string-db.org/network/171101.spr0151Hypothetical protein.
spr0152 protein networkhttps://string-db.org/network/171101.spr0152Conserved hypothetical protein.
hk07 protein networkhttps://string-db.org/network/171101.spr0153Histidine kinase.
rr07 protein networkhttps://string-db.org/network/171101.spr0154Response regulator.
spr0155 protein networkhttps://string-db.org/network/171101.spr0155Hypothetical protein.
spr0156 protein networkhttps://string-db.org/network/171101.spr0156Conserved hypothetical protein; Similar to NrdI protein.
spr0157 protein networkhttps://string-db.org/network/171101.spr0157Conserved hypothetical protein.
spr0158 protein networkhttps://string-db.org/network/171101.spr0158Hypothetical protein.
spr0159 protein networkhttps://string-db.org/network/171101.spr0159Conserved hypothetical protein; Similar to autolysin response regulator in Bacillus subtilis.
hexB protein networkhttps://string-db.org/network/171101.spr0160DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. The hex system is nick-directed.
ribE protein networkhttps://string-db.org/network/171101.spr0161Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is t [...]
ribA protein networkhttps://string-db.org/network/171101.spr0162Riboflavin biosynthesis; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II fa [...]
ribC protein networkhttps://string-db.org/network/171101.spr0163Riboflavin synthase alpha-chain.
ribD protein networkhttps://string-db.org/network/171101.spr0164Riboflavin biosynthese; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; b [...]
ruvA protein networkhttps://string-db.org/network/171101.spr0165Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exch [...]
tag protein networkhttps://string-db.org/network/171101.spr01663-Methyladenine DNA glycosylase I, constitutive.
spr0167 protein networkhttps://string-db.org/network/171101.spr0167Conserved hypothetical protein.
spr0168 protein networkhttps://string-db.org/network/171101.spr0168Conserved hypothetical protein; MccF-like proteins.
spr0169 protein networkhttps://string-db.org/network/171101.spr0169Hypothetical protein.
corA protein networkhttps://string-db.org/network/171101.spr0170Magnesium and cobalt transporter.
uvrA protein networkhttps://string-db.org/network/171101.spr0171Excinuclease ABC - subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed [...]
pepP protein networkhttps://string-db.org/network/171101.spr0172Aminopeptidase P; Belongs to the peptidase M24B family.
arsC protein networkhttps://string-db.org/network/171101.spr0173Arsenate reductase, putative; Belongs to the ArsC family.
spr0174 protein networkhttps://string-db.org/network/171101.spr0174Hypothetical protein.
spr0175 protein networkhttps://string-db.org/network/171101.spr0175Hypothetical protein; Belongs to the UPF0297 family.
spr0176 protein networkhttps://string-db.org/network/171101.spr0176Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
spr0177 protein networkhttps://string-db.org/network/171101.spr0177Conserved hypothetical protein; Belongs to the UPF0473 family.
folC protein networkhttps://string-db.org/network/171101.spr0178Dihydrofolate:folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family.
spr0179 protein networkhttps://string-db.org/network/171101.spr0179Hypothetical protein.
cls protein networkhttps://string-db.org/network/171101.spr0180Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belong [...]
orf47 protein networkhttps://string-db.org/network/171101.spr0181Orf47; Induced during competence.
spr0182 protein networkhttps://string-db.org/network/171101.spr0182Competence-induced protein Ccs4.
nrdD protein networkhttps://string-db.org/network/171101.spr0183Ribonucleotide reductase, class III, anaerobic.
spr0184 protein networkhttps://string-db.org/network/171101.spr0184Hypothetical protein; Similar to histone acetyltransferase HPA2 and related acetyltransferases.
nrdG protein networkhttps://string-db.org/network/171101.spr0185NrdD activating enzyme, generating glycyl radical; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adeno [...]
spr0186 protein networkhttps://string-db.org/network/171101.spr0186Hypothetical protein.
rpsJ protein networkhttps://string-db.org/network/171101.spr018730S Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
rplC protein networkhttps://string-db.org/network/171101.spr018850S Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal rib [...]
rplD protein networkhttps://string-db.org/network/171101.spr018950S Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes [...]
rplW protein networkhttps://string-db.org/network/171101.spr019050S Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main dock [...]
rplB protein networkhttps://string-db.org/network/171101.spr019150S Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rpsS protein networkhttps://string-db.org/network/171101.spr019230S Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
spr0193 protein networkhttps://string-db.org/network/171101.spr0193Hypothetical protein.
rplV protein networkhttps://string-db.org/network/171101.spr019450S Ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50 [...]
rpsC protein networkhttps://string-db.org/network/171101.spr019530S Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplP protein networkhttps://string-db.org/network/171101.spr019650S Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpmC protein networkhttps://string-db.org/network/171101.spr019750S Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
rpsQ protein networkhttps://string-db.org/network/171101.spr019830S Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rplN protein networkhttps://string-db.org/network/171101.spr019950S Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rplX protein networkhttps://string-db.org/network/171101.spr020050S Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rplE protein networkhttps://string-db.org/network/171101.spr020150S Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [...]
rpsN protein networkhttps://string-db.org/network/171101.spr020230S Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the un [...]
rpsH protein networkhttps://string-db.org/network/171101.spr020330S Ribosomal protein S8 (S8); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belong [...]
rplF protein networkhttps://string-db.org/network/171101.spr020450S Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the t [...]
rplR protein networkhttps://string-db.org/network/171101.spr020550S Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protubera [...]
rpsE protein networkhttps://string-db.org/network/171101.spr020630S Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
rpmD protein networkhttps://string-db.org/network/171101.spr020750S Ribosomal protein L30.
rplO protein networkhttps://string-db.org/network/171101.spr020850S Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
secY protein networkhttps://string-db.org/network/171101.spr0209Multispanning membrane protein, translocator of proteins; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains for [...]
adk protein networkhttps://string-db.org/network/171101.spr0210Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in [...]
infA protein networkhttps://string-db.org/network/171101.spr0211Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
rpmJ protein networkhttps://string-db.org/network/171101.spr021250S Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
rpsM protein networkhttps://string-db.org/network/171101.spr021330S Ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 [...]
rpsK protein networkhttps://string-db.org/network/171101.spr021430S Ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
rpoA protein networkhttps://string-db.org/network/171101.spr0215RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplQ protein networkhttps://string-db.org/network/171101.spr021650S Ribosomal protein L17.
spr0217 protein networkhttps://string-db.org/network/171101.spr0217Conserved hypothetical protein; ACT domain containing protein.
spr0218 protein networkhttps://string-db.org/network/171101.spr0218Conserved hypothetical protein.
gpmB protein networkhttps://string-db.org/network/171101.spr0219Phosphoglycerate mutase 2 paralog.
ABC-MSP-4 protein networkhttps://string-db.org/network/171101.spr0220ABC transporter membrane-spanning permease - iron transport.
ABC-MSP-5 protein networkhttps://string-db.org/network/171101.spr0221ABC transporter membrane-spanning permease - iron transport.
ABC-NBD-3 protein networkhttps://string-db.org/network/171101.spr0222ABC transporter ATP-binding protein - iron transport; Belongs to the ABC transporter superfamily.
spr0223 protein networkhttps://string-db.org/network/171101.spr0223ABC transporter solute-binding protein - iron transport, truncation.
spr0224 protein networkhttps://string-db.org/network/171101.spr0224ABC transporter substrate-binding protein - iron transport, truncation.
spr0225 protein networkhttps://string-db.org/network/171101.spr0225Hypothetical protein.
pflE protein networkhttps://string-db.org/network/171101.spr0226Pyruvate formate-lyase 3.
deoR protein networkhttps://string-db.org/network/171101.spr0227DEOR-type transcriptional regulator.
spr0228 protein networkhttps://string-db.org/network/171101.spr0228Conserved hypothetical protein; Resembles sorbitol operon regulator.
PTS-EIIA protein networkhttps://string-db.org/network/171101.spr0229Phosphotransferase system sugar-specific EIIA component.
PTS-EIIB-2 protein networkhttps://string-db.org/network/171101.spr0230Phosphotransferase system sugar-specific EIIB component.
PTS-EIIC-2 protein networkhttps://string-db.org/network/171101.spr0231Phosphotransferase system sugar-specific EIIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phos [...]
pflF protein networkhttps://string-db.org/network/171101.spr0232Formate acetyltransferase 3.
talC protein networkhttps://string-db.org/network/171101.spr0233Transaldolase C.
gldA protein networkhttps://string-db.org/network/171101.spr0234Glycerol dehydrogenase, NAD+ dependent.
leuS protein networkhttps://string-db.org/network/171101.spr0235Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
spr0236 protein networkhttps://string-db.org/network/171101.spr0236Conserved hypothetical protein; Similar to acetyltransferases, including N-acetylases of ribosomal proteins.
spr0237 protein networkhttps://string-db.org/network/171101.spr0237Conserved hypothetical protein; Similar to histone acetyltransferase HPA2 and related acetyltransferases.
ruvB protein networkhttps://string-db.org/network/171101.spr0238Branch migration of Holliday structures; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote st [...]
spr0239 protein networkhttps://string-db.org/network/171101.spr0239Hypothetical protein.
uppS protein networkhttps://string-db.org/network/171101.spr0240Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
cdsA protein networkhttps://string-db.org/network/171101.spr0241Phosphatidate cytidylyltransferase; Belongs to the CDS family.
eep protein networkhttps://string-db.org/network/171101.spr0242Determinant for enhanced expression of pheromone; Belongs to the peptidase M50B family.
proS protein networkhttps://string-db.org/network/171101.spr0243Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
bglA protein networkhttps://string-db.org/network/171101.spr02446-phospho-beta-glucosidase; Belongs to the glycosyl hydrolase 1 family.
glmS protein networkhttps://string-db.org/network/171101.spr0245L-glutamine-D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
spr0246 protein networkhttps://string-db.org/network/171101.spr0246Conserved hypothetical protein; Similar to coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and and related flavin-dependent oxidoreductases.
pulA protein networkhttps://string-db.org/network/171101.spr0247Alkaline amylopullulanase.
rpsL protein networkhttps://string-db.org/network/171101.spr024830S Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
rpsG protein networkhttps://string-db.org/network/171101.spr024930S Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit inte [...]
fusA protein networkhttps://string-db.org/network/171101.spr0250Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- [...]
polC protein networkhttps://string-db.org/network/171101.spr0251DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
spr0252 protein networkhttps://string-db.org/network/171101.spr0252Hypothetical protein.
spr0253 protein networkhttps://string-db.org/network/171101.spr0253Conserved hypothetical protein.
pepS protein networkhttps://string-db.org/network/171101.spr0254Aminopeptidase.
spr0255 protein networkhttps://string-db.org/network/171101.spr0255Conserved hypothetical protein.
rsuA protein networkhttps://string-db.org/network/171101.spr0256Ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family.
spr0257 protein networkhttps://string-db.org/network/171101.spr0257Hypothetical protein.
pepC protein networkhttps://string-db.org/network/171101.spr0258Aminopeptidase C; Belongs to the peptidase C1 family.
manN protein networkhttps://string-db.org/network/171101.spr0259Phosphotransferase system, mannose-specific EIID.
manM protein networkhttps://string-db.org/network/171101.spr0260Phosphotransferase system, mannose-specific EIIC.
manL protein networkhttps://string-db.org/network/171101.spr0261Phosphotransferase system, mannose-specific EIIAB.
adhP protein networkhttps://string-db.org/network/171101.spr0262Alcohol dehydrogenase, propanol-preferring.
spr0263 protein networkhttps://string-db.org/network/171101.spr0263Conserved hypothetical protein.
spr0264 protein networkhttps://string-db.org/network/171101.spr0264Conserved hypothetical protein.
spr0265 protein networkhttps://string-db.org/network/171101.spr0265Conserved hypothetical protein.
sulA protein networkhttps://string-db.org/network/171101.spr0266Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate, the immediate precurso [...]
sulB protein networkhttps://string-db.org/network/171101.spr0267Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.
sulC protein networkhttps://string-db.org/network/171101.spr0268GTP cyclohydrolase.
sulD protein networkhttps://string-db.org/network/171101.spr0269Aldolase-pyrophosphokinase; Catalyzes two sequential steps of tetrahydrofolate biosynthesis, the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin diphosphate. In the N-ter [...]
spr0270 protein networkhttps://string-db.org/network/171101.spr0270Hypothetical protein.
rplM protein networkhttps://string-db.org/network/171101.spr027150S Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages [...]
rpsI protein networkhttps://string-db.org/network/171101.spr027230S Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
spr0273 protein networkhttps://string-db.org/network/171101.spr0273Degenerate transposase.
spr0274 protein networkhttps://string-db.org/network/171101.spr0274Phospho-beta-glucosidase, truncation.
spr0275 protein networkhttps://string-db.org/network/171101.spr0275Hypothetical protein.
bglA-2 protein networkhttps://string-db.org/network/171101.spr02766-phospho-beta-glucosidase; Belongs to the glycosyl hydrolase 1 family.
spr0277 protein networkhttps://string-db.org/network/171101.spr0277Conserved hypothetical protein.
PTS-EII-2 protein networkhttps://string-db.org/network/171101.spr0278Phosphotransferase system sugar-specific EII component.
bglG protein networkhttps://string-db.org/network/171101.spr0279Transcription antiterminator BglG family.
PTS-EII-3 protein networkhttps://string-db.org/network/171101.spr0280Phosphotransferase system sugar-specific EII component.
spr0281 protein networkhttps://string-db.org/network/171101.spr0281Hypothetical protein.
PTS-EII-4 protein networkhttps://string-db.org/network/171101.spr0282Phosphotransferase system sugar-specific EII component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosp [...]
spr0283 protein networkhttps://string-db.org/network/171101.spr0283Hypothetical protein.
xylS protein networkhttps://string-db.org/network/171101.spr0284Alpha-xylosidase; Belongs to the glycosyl hydrolase 31 family.
basA protein networkhttps://string-db.org/network/171101.spr0285Gluthatione peroxidase; Belongs to the glutathione peroxidase family.
hysA protein networkhttps://string-db.org/network/171101.spr0286Hyaluronate lyase precursor (hyaluronidase/hyase).
kdgA protein networkhttps://string-db.org/network/171101.spr02872-keto-3-deoxy-6-phosphogluconate aldolase.
kdgK protein networkhttps://string-db.org/network/171101.spr02882-keto-3-deoxygluconate kinase.
spr0289 protein networkhttps://string-db.org/network/171101.spr0289Hypothetical protein.
gno protein networkhttps://string-db.org/network/171101.spr02905-keto-D-gluconate 5-reductase.
PTS-EII-5 protein networkhttps://string-db.org/network/171101.spr0291Phosphotransferase system sugar-specific EII component.
ugl protein networkhttps://string-db.org/network/171101.spr0292Unsaturated glucuronyl hydrolase; Catalyzes the hydrolysis of unsaturated hyaluronate and chondroitin disaccharides. Also degrades unsaturated heparin disaccharides. Releases 4-deoxy-4,5-didehydr [...]
PTS-EII-6 protein networkhttps://string-db.org/network/171101.spr0293Phosphotransferase system sugar-specific EII component.
PTS-EII-7 protein networkhttps://string-db.org/network/171101.spr0294Phosphotransferase system sugar-specific EII component.
PTS-EII-8 protein networkhttps://string-db.org/network/171101.spr0295Phosphotransferase system sugar-specific EII component.
spr0296 protein networkhttps://string-db.org/network/171101.spr0296Conserved hypothetical protein.
spr0297 protein networkhttps://string-db.org/network/171101.spr0297Hypothetical protein.
regR protein networkhttps://string-db.org/network/171101.spr0298Transcription regulator, member of GalR family.
spr0299 protein networkhttps://string-db.org/network/171101.spr0299Hypothetical protein, truncation.
spr0300 protein networkhttps://string-db.org/network/171101.spr0300Hypothetical protein, truncation.
yorfE protein networkhttps://string-db.org/network/171101.spr0301Transcription regulator.
yllC protein networkhttps://string-db.org/network/171101.spr0302YllC protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
ftsL protein networkhttps://string-db.org/network/171101.spr0303Cell division protein; Essential cell division protein; Belongs to the FtsL family.
pbpX protein networkhttps://string-db.org/network/171101.spr0304Penicillin-binding protein 2X; Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Beta-lactams inactivate the PBPs by acylating an essential serine residue in t [...]
mraY protein networkhttps://string-db.org/network/171101.spr0305Undecaprenyl-phosphate-UDP-MurNAc-pentapeptide phospho-MurNAc-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the [...]
spr0306 protein networkhttps://string-db.org/network/171101.spr0306Hypothetical protein.
clpL protein networkhttps://string-db.org/network/171101.spr0307ATP-dependent protease ATP-binding subunit; Belongs to the ClpA/ClpB family.
luxS protein networkhttps://string-db.org/network/171101.spr0308Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of t [...]
spr0309 protein networkhttps://string-db.org/network/171101.spr0309Hypothetical protein; Belongs to the UPF0371 family.
dexB protein networkhttps://string-db.org/network/171101.spr0310Alpha, 1-6-glucosidase.
spr0311 protein networkhttps://string-db.org/network/171101.spr0311Hypothetical protein.
spr0313 protein networkhttps://string-db.org/network/171101.spr0313Transposase.
cps2A protein networkhttps://string-db.org/network/171101.spr0314The type 2 capsule locus of Streptococcus pneumoniae.
cps2H protein networkhttps://string-db.org/network/171101.spr0315The type 2 capsule locus of Streptococcus pneumoniae.
cps2I protein networkhttps://string-db.org/network/171101.spr0316The type 2 capsule locus of Streptococcus pneumoniae.
cps2J protein networkhttps://string-db.org/network/171101.spr0317The type 2 capsule locus of Streptococcus pneumoniae.
cps2K protein networkhttps://string-db.org/network/171101.spr0318The type 2 capsule locus of Streptococcus pneumoniae.
cps2P protein networkhttps://string-db.org/network/171101.spr0319The type 2 capsule locus of Streptococcus pneumoniae.
cps2L protein networkhttps://string-db.org/network/171101.spr0320The type 2 capsule locus of Streptococcus pneumoniae; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosp [...]
cps2M protein networkhttps://string-db.org/network/171101.spr0321The type 2 capsule locus of Streptococcus pneumoniae.
cpsN protein networkhttps://string-db.org/network/171101.spr0322dTDP-glucose-4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
cpsO protein networkhttps://string-db.org/network/171101.spr0323dTDP-L-rhamnose synthase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
spr0324 protein networkhttps://string-db.org/network/171101.spr0324Transposase, uncharacterized, truncation.
spr0325 protein networkhttps://string-db.org/network/171101.spr0325Hypothetical protein.
spr0326 protein networkhttps://string-db.org/network/171101.spr0326Hypothetical protein.
aliA protein networkhttps://string-db.org/network/171101.spr0327ABC transporter substrate-binding protein - oligopeptide transport.
spr0328 protein networkhttps://string-db.org/network/171101.spr0328Conserved hypothetical protein; Involved in the breakdown of mucin-type O-linked glycans. Specifically removes the T-antigen disaccharide (Gal-beta-1,3-GalNAc- alpha) from extracellular host glyc [...]
pbpA protein networkhttps://string-db.org/network/171101.spr0329Penicillin-binding protein 1A; Cell wall formation; In the C-terminal section; belongs to the transpeptidase family.
recU protein networkhttps://string-db.org/network/171101.spr0330Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired stran [...]
spr0331 protein networkhttps://string-db.org/network/171101.spr0331Conserved hypothetical protein; Belongs to the UPF0398 family.
gpsB protein networkhttps://string-db.org/network/171101.spr0332Conserved hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to th [...]
spr0333 protein networkhttps://string-db.org/network/171101.spr0333Conserved hypothetical protein; Belongs to the methyltransferase superfamily.
mapZ protein networkhttps://string-db.org/network/171101.spr0334Conserved hypothetical protein; Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning.
gnd protein networkhttps://string-db.org/network/171101.spr03356-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
csrR protein networkhttps://string-db.org/network/171101.spr0336Response regulator.
cbpF protein networkhttps://string-db.org/network/171101.spr0337Choline-binding protein F.
mvk protein networkhttps://string-db.org/network/171101.spr0338Mevalonate kinase.
mvd1 protein networkhttps://string-db.org/network/171101.spr0339Diphosphomevalonate decarboxylase.
mvaK2 protein networkhttps://string-db.org/network/171101.spr0340Phosphomevalonate kinase.
fni protein networkhttps://string-db.org/network/171101.spr0341Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimet [...]
spr0342 protein networkhttps://string-db.org/network/171101.spr0342Conserved hypothetical protein.
hk03 protein networkhttps://string-db.org/network/171101.spr0343Histidine kinase.
rr03 protein networkhttps://string-db.org/network/171101.spr0344Response regulator.
spr0345 protein networkhttps://string-db.org/network/171101.spr0345DNA alkylation repair enzyme, truncation.
spr0346 protein networkhttps://string-db.org/network/171101.spr0346DNA alkylation repair enzyme, truncation.
spr0347 protein networkhttps://string-db.org/network/171101.spr0347DNA alkylation repair enzyme, truncation.
spr0348 protein networkhttps://string-db.org/network/171101.spr0348Hypothetical protein.
spr0349 protein networkhttps://string-db.org/network/171101.spr0349Choline binding protein G, truncation.
cbpG protein networkhttps://string-db.org/network/171101.spr0350Choline binding protein G.
pcpC protein networkhttps://string-db.org/network/171101.spr0351Choline-binding protein.
spr0352 protein networkhttps://string-db.org/network/171101.spr0352Degenerate transposase (orf2).
spr0353 protein networkhttps://string-db.org/network/171101.spr0353Degenerate transposase (orf2).
spr0354 protein networkhttps://string-db.org/network/171101.spr0354Degenerate transposase (orf2).
spr0355 protein networkhttps://string-db.org/network/171101.spr0355Degenerate transposase (orf1).
mtlA protein networkhttps://string-db.org/network/171101.spr0356Mannitol PTS EII; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar subs [...]
spr0357 protein networkhttps://string-db.org/network/171101.spr0357Conserved hypothetical protein; Putative transcriptional regulator.
mtlF protein networkhttps://string-db.org/network/171101.spr0358Mannitol-specific enzyme IIA component.
mtlD protein networkhttps://string-db.org/network/171101.spr0359Mannitol-1-phosphate 5-dehydrogenase.
spr0360 protein networkhttps://string-db.org/network/171101.spr0360Hypothetical protein.
spr0361 protein networkhttps://string-db.org/network/171101.spr0361Conserved hypothetical protein.
ropA protein networkhttps://string-db.org/network/171101.spr0362Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs t [...]
recD protein networkhttps://string-db.org/network/171101.spr0363Exonuclease V; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belo [...]
spi protein networkhttps://string-db.org/network/171101.spr0364Signal peptidase I; Belongs to the peptidase S26 family.
rnhB protein networkhttps://string-db.org/network/171101.spr0365Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. RnhC subfamily.
spr0366 protein networkhttps://string-db.org/network/171101.spr0366Hypothetical protein.
spr0367 protein networkhttps://string-db.org/network/171101.spr0367Conserved hypothetical protein.
mutS2 protein networkhttps://string-db.org/network/171101.spr0368DNA mismatch repair protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs [...]
dagA protein networkhttps://string-db.org/network/171101.spr0369D-alanine glycine permease.
mip protein networkhttps://string-db.org/network/171101.spr0370Macrophage infectivity potentiator protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration [...]
shetA protein networkhttps://string-db.org/network/171101.spr0371Exfoliative toxin A.
serS protein networkhttps://string-db.org/network/171101.spr0372Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
spr0373 protein networkhttps://string-db.org/network/171101.spr0373Conserved hypothetical protein.
lysC protein networkhttps://string-db.org/network/171101.spr0374Aspartate kinase; Belongs to the aspartokinase family.
phaB protein networkhttps://string-db.org/network/171101.spr0375Enoyl-CoA hydratase II; Catalyzes the isomerization of trans-2-decenoyl-ACP to cis-3- decenoyl-ACP. Most active with 10-carbon enoyl-ACP. Can also use 12- carbon enoyl-ACP as substrate, but not 1 [...]
spr0376 protein networkhttps://string-db.org/network/171101.spr0376Conserved hypothetical protein; Probable transcriptional regulator.
fabH protein networkhttps://string-db.org/network/171101.spr03773-oxoacyl-acyl-carrier-protein synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first c [...]
acp protein networkhttps://string-db.org/network/171101.spr0378Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
fabK protein networkhttps://string-db.org/network/171101.spr0379Enoyl-acyl carrier protein(ACP) reductase.
fabD protein networkhttps://string-db.org/network/171101.spr0380Malonyl acyl carrier protein transacylase.
fabG protein networkhttps://string-db.org/network/171101.spr03813-ketoacyl-acyl carrier protein reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cyc [...]
fabF protein networkhttps://string-db.org/network/171101.spr0382Beta ketoacyl-acyl carrier protein synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
accB protein networkhttps://string-db.org/network/171101.spr0383Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the c [...]
fabZ protein networkhttps://string-db.org/network/171101.spr0384Hydroxymyristoyl-(acyl carrier protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and [...]
accC protein networkhttps://string-db.org/network/171101.spr0385Biotin carboxylase (a subunit of acetyl-CoA carboxylase (ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of t [...]
accD protein networkhttps://string-db.org/network/171101.spr0386Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its [...]
accA protein networkhttps://string-db.org/network/171101.spr0387Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on [...]
spr0388 protein networkhttps://string-db.org/network/171101.spr0388Hypothetical protein.
spr0389 protein networkhttps://string-db.org/network/171101.spr0389Hypothetical protein.
nusB protein networkhttps://string-db.org/network/171101.spr0390Transcription termination protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of t [...]
spr0391 protein networkhttps://string-db.org/network/171101.spr0391Conserved hypothetical protein.
efp protein networkhttps://string-db.org/network/171101.spr0392Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirect [...]
gatB protein networkhttps://string-db.org/network/171101.spr0393Glutamyl tRNA-Gln amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in [...]
gatA protein networkhttps://string-db.org/network/171101.spr0394Glu-tRNAGln amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA syn [...]
gatC protein networkhttps://string-db.org/network/171101.spr0395Glutamyl tRNA-Gln amidotransferase, subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in [...]
prfC protein networkhttps://string-db.org/network/171101.spr0396Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for U [...]
spr0397 protein networkhttps://string-db.org/network/171101.spr0397Conserved hypothetical protein.
rpmB protein networkhttps://string-db.org/network/171101.spr039850S Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
asp23 protein networkhttps://string-db.org/network/171101.spr0399Alkaline shock protein.
spr0400 protein networkhttps://string-db.org/network/171101.spr0400Conserved hypothetical protein.
ilvB protein networkhttps://string-db.org/network/171101.spr0401Acetolactate synthase large subunit.
ilvN protein networkhttps://string-db.org/network/171101.spr0402Acetolactate synthase small subunit.
ilvC protein networkhttps://string-db.org/network/171101.spr0403Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yie [...]
spr0404 protein networkhttps://string-db.org/network/171101.spr0404Hypothetical protein.
spr0405 protein networkhttps://string-db.org/network/171101.spr0405Hypothetical protein.
ilvA protein networkhttps://string-db.org/network/171101.spr0406Threonine desaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a productio [...]
glnQ protein networkhttps://string-db.org/network/171101.spr0408ABC transporter ATP-binding protein - glutamine.
glnH protein networkhttps://string-db.org/network/171101.spr0409ABC transporter substrate binding protein - glutamine transport.
spr0411 protein networkhttps://string-db.org/network/171101.spr0411Degenerate transposase.
spr0412 protein networkhttps://string-db.org/network/171101.spr0412Degenerate transposase.
bacA protein networkhttps://string-db.org/network/171101.spr0413A lipid kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
dinP protein networkhttps://string-db.org/network/171101.spr0414DNA-damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from misma [...]
pfl protein networkhttps://string-db.org/network/171101.spr0415Pyruvate formate-lyase.
spr0416 protein networkhttps://string-db.org/network/171101.spr0416Hypothetical protein.
spr0417 protein networkhttps://string-db.org/network/171101.spr0417Conserved hypothetical protein.
xylR protein networkhttps://string-db.org/network/171101.spr0420Xylose repressor protein.
PTS-EII-9 protein networkhttps://string-db.org/network/171101.spr0421Phosphotransferase system sugar-specific EII component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosp [...]
spr0422 protein networkhttps://string-db.org/network/171101.spr0422Hypothetical protein.
PTS-EII-10 protein networkhttps://string-db.org/network/171101.spr0423Phosphotransferase system sugar-specific EII component.
lacG protein networkhttps://string-db.org/network/171101.spr0424Phospho-beta-D-galactosidase; Belongs to the glycosyl hydrolase 1 family.
PTS-EII-11 protein networkhttps://string-db.org/network/171101.spr0425Phosphotransferase system sugar-specific EII component.
trkH-2 protein networkhttps://string-db.org/network/171101.spr0426Trk transporter membrane-spanning protein - K+ transport.
trkA-2 protein networkhttps://string-db.org/network/171101.spr0427Trk transporter NAD+ binding protein - K+ transport.
spr0428 protein networkhttps://string-db.org/network/171101.spr0428Conserved hypothetical protein.
spr0429 protein networkhttps://string-db.org/network/171101.spr0429Conserved hypothetical protein.
ABC-NBD-4 protein networkhttps://string-db.org/network/171101.spr0430ABC transporter ATP-binding protein - cobalt transport; Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
ABC-MSD-2 protein networkhttps://string-db.org/network/171101.spr0431ABC transporter membrane-spanning permease - unknown substrate.
cspR protein networkhttps://string-db.org/network/171101.spr0432rRNA methylase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. [...]
spr0433 protein networkhttps://string-db.org/network/171101.spr0433Conserved hypothetical protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC- [...]
spr0434 protein networkhttps://string-db.org/network/171101.spr0434Conserved hypothetical protein; Probable phosphatidic acid phosphatase.
spr0435 protein networkhttps://string-db.org/network/171101.spr0435Hypothetical protein.
spr0436 protein networkhttps://string-db.org/network/171101.spr0436Hypothetical protein.
rpoE protein networkhttps://string-db.org/network/171101.spr0437RNA polymerase (delta subunit); Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcri [...]
pyrG protein networkhttps://string-db.org/network/171101.spr0438CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the [...]
spr0439 protein networkhttps://string-db.org/network/171101.spr0439Conserved hypothetical protein; Probable integral membrane protein.
spr0440 protein networkhttps://string-db.org/network/171101.spr0440Hypothetical protein; Similar to endo-beta-N-acetylglucosaminidase.
pgk protein networkhttps://string-db.org/network/171101.spr0441Phosphoglycerate kinase.
spr0442 protein networkhttps://string-db.org/network/171101.spr0442Hypothetical protein.
glnR protein networkhttps://string-db.org/network/171101.spr0443Transcriptional repressor of the glutamine synthetase gene.
glnA protein networkhttps://string-db.org/network/171101.spr0444Glutamine synthetase type 1.
hsdS protein networkhttps://string-db.org/network/171101.spr0445Type I restriction enzyme.
hsdS-2 protein networkhttps://string-db.org/network/171101.spr0446Type I restriction enzyme EcoKI specificity protein (S protein).
xerD protein networkhttps://string-db.org/network/171101.spr0447Integrase/recombinase; Belongs to the 'phage' integrase family.
hsdS-3 protein networkhttps://string-db.org/network/171101.spr0448Type I site-specific deoxyribonuclease chain S.
hsdM protein networkhttps://string-db.org/network/171101.spr0449EcoE type I restriction modification enzyme M subunit.
hsdR protein networkhttps://string-db.org/network/171101.spr0450EcoA type I restriction-modification enzyme R subunit.
spr0451 protein networkhttps://string-db.org/network/171101.spr0451Hypothetical protein.
spr0452 protein networkhttps://string-db.org/network/171101.spr0452Hypothetical protein.
hrcA protein networkhttps://string-db.org/network/171101.spr0453Heat inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
grpE protein networkhttps://string-db.org/network/171101.spr0454Heat-shock protein (activation of DnaK); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK [...]
dnaK protein networkhttps://string-db.org/network/171101.spr0455Class I heat-shock protein (molecular chaperone); Acts as a chaperone; Belongs to the heat shock protein 70 family.
dnaJ protein networkhttps://string-db.org/network/171101.spr0456Heat-shock protein (activation of DnaK); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating prot [...]
spr0457 protein networkhttps://string-db.org/network/171101.spr0457Hypothetical protein.
spr0458 protein networkhttps://string-db.org/network/171101.spr0458Conserved hypothetical protein; HIT-like protein.
ABC-NBD-5 protein networkhttps://string-db.org/network/171101.spr0459ABC transporter ATP-binding protein - unknown substrate.
ABC-MSP-6 protein networkhttps://string-db.org/network/171101.spr0460ABC transporter membrane-spanning permease - unknown substrate.
blpT protein networkhttps://string-db.org/network/171101.spr0461Hypothetical protein.
blpS protein networkhttps://string-db.org/network/171101.spr0462Regulatory protein.
rr13 protein networkhttps://string-db.org/network/171101.spr0463Response regulator.
hk13 protein networkhttps://string-db.org/network/171101.spr0464Histidine kinase.
ip protein networkhttps://string-db.org/network/171101.spr0465Bacteriocin-like peptide, double glycine cleavage type.
spr0466 protein networkhttps://string-db.org/network/171101.spr0466Conserved hypothetical protein, truncation; blpB.
spr0467 protein networkhttps://string-db.org/network/171101.spr0467Conserved hypothetical protein, truncation; blpB.
spr0468 protein networkhttps://string-db.org/network/171101.spr0468Conserved hypothetical protein, truncation; blpA.
spr0469 protein networkhttps://string-db.org/network/171101.spr0469Conserved hypothetical protein, truncation; blpA.
spr0470 protein networkhttps://string-db.org/network/171101.spr0470Hypothetical protein.
spr0471 protein networkhttps://string-db.org/network/171101.spr0471Hypothetical protein.
blpY protein networkhttps://string-db.org/network/171101.spr0472BlpY protein.
blpZ protein networkhttps://string-db.org/network/171101.spr0473Hypothetical protein.
pncP protein networkhttps://string-db.org/network/171101.spr0474ABC transporter ATP binding protein - unknown substrate.
spr0475 protein networkhttps://string-db.org/network/171101.spr0475Conserved hypothetical protein.
trmB protein networkhttps://string-db.org/network/171101.spr0476Conserved hypothetical protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
rimP protein networkhttps://string-db.org/network/171101.spr0477Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
nusA protein networkhttps://string-db.org/network/171101.spr0478Transcription termination; Participates in both transcription termination and antitermination.
spr0479 protein networkhttps://string-db.org/network/171101.spr0479Conserved hypothetical protein.
spr0480 protein networkhttps://string-db.org/network/171101.spr0480Conserved hypothetical protein; Probable ribosomal protein.
infB protein networkhttps://string-db.org/network/171101.spr0481Initiation factor IF2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribos [...]
rbfA protein networkhttps://string-db.org/network/171101.spr0482Ribosome binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
spr0483 protein networkhttps://string-db.org/network/171101.spr0483Conserved hypothetical protein.
spr0484 protein networkhttps://string-db.org/network/171101.spr0484Hypothetical protein.
spr0485 protein networkhttps://string-db.org/network/171101.spr0485Hypothetical protein.
spr0486 protein networkhttps://string-db.org/network/171101.spr0486Conserved hypothetical protein.
spr0487 protein networkhttps://string-db.org/network/171101.spr0487Hypothetical protein.
spr0488 protein networkhttps://string-db.org/network/171101.spr0488Hypothetical protein.
spr0489 protein networkhttps://string-db.org/network/171101.spr0489Hypothetical protein.
spr0490 protein networkhttps://string-db.org/network/171101.spr0490Conserved hypothetical protein; Probable acetyl transferase.
spr0491 protein networkhttps://string-db.org/network/171101.spr0491Hypothetical protein.
valS protein networkhttps://string-db.org/network/171101.spr0492Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
spr0493 protein networkhttps://string-db.org/network/171101.spr0493Conserved hypothetical protein.
spr0494 protein networkhttps://string-db.org/network/171101.spr0494Hypothetical protein.
spr0495 protein networkhttps://string-db.org/network/171101.spr0495Degenerate transposase (orf2).
spr0496 protein networkhttps://string-db.org/network/171101.spr0496Degenerate transposase (orf2).
spr0497 protein networkhttps://string-db.org/network/171101.spr0497Degenerate transposase (orf2).
spr0498 protein networkhttps://string-db.org/network/171101.spr0498Degenerate transposase (orf1).
spr0499 protein networkhttps://string-db.org/network/171101.spr0499Hypothetical protein.
spr0500 protein networkhttps://string-db.org/network/171101.spr0500Hypothetical protein.
spr0501 protein networkhttps://string-db.org/network/171101.spr0501Hypothetical protein.
spr0502 protein networkhttps://string-db.org/network/171101.spr0502Hypothetical protein.
spr0503 protein networkhttps://string-db.org/network/171101.spr0503Hypothetical protein.
licT protein networkhttps://string-db.org/network/171101.spr0504Transcriptional antiterminator (BglG family).
PTS-EII-12 protein networkhttps://string-db.org/network/171101.spr0505Phosphotransferase system sugar-specific EII component.
bglH protein networkhttps://string-db.org/network/171101.spr05066-phospho-beta-glucosidase; Belongs to the glycosyl hydrolase 1 family.
pheS protein networkhttps://string-db.org/network/171101.spr0507Phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
spr0508 protein networkhttps://string-db.org/network/171101.spr0508Conserved hypothetical protein; Probable transcriptional regulator.
pheT protein networkhttps://string-db.org/network/171101.spr0509Phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
spr0510 protein networkhttps://string-db.org/network/171101.spr0510Hypothetical protein.
spr0511 protein networkhttps://string-db.org/network/171101.spr0511Degenerate transposase.
spr0512 protein networkhttps://string-db.org/network/171101.spr0512Degenerate transposase.
spr0513 protein networkhttps://string-db.org/network/171101.spr0513Conserved hypothetical protein.
metE protein networkhttps://string-db.org/network/171101.spr0514Tetrahydropteroyltriglutamate methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin- [...]
metF protein networkhttps://string-db.org/network/171101.spr05155,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
pnpA protein networkhttps://string-db.org/network/171101.spr0516Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
cysE protein networkhttps://string-db.org/network/171101.spr0517Serine acetyltransferase.
spr0518 protein networkhttps://string-db.org/network/171101.spr0518Hypothetical protein.
cysS protein networkhttps://string-db.org/network/171101.spr0519Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
mrnC protein networkhttps://string-db.org/network/171101.spr0520Conserved hypothetical protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); R [...]
spr0521 protein networkhttps://string-db.org/network/171101.spr0521Conserved hypothetical protein; Leucine rich protein.
spr0522 protein networkhttps://string-db.org/network/171101.spr0522Hypothetical protein.
spr0523 protein networkhttps://string-db.org/network/171101.spr0523Transposase, uncharacterized, truncation.
vex1 protein networkhttps://string-db.org/network/171101.spr0524ABC transporter membrane-spanning permease - Pep export.
vex2 protein networkhttps://string-db.org/network/171101.spr0525ABC transporter ATP-binding protein - Pep export.
vex3 protein networkhttps://string-db.org/network/171101.spr0526ABC transporter membrane-spanning permease - Pep export.
pep27 protein networkhttps://string-db.org/network/171101.spr0527A secreted peptide which is the signal sensed by VncR/S.
vncR protein networkhttps://string-db.org/network/171101.spr0528VncR, response regulator.
vncS protein networkhttps://string-db.org/network/171101.spr0529VncS, histidine kinase.
fba protein networkhttps://string-db.org/network/171101.spr0530Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphat [...]
spr0531 protein networkhttps://string-db.org/network/171101.spr0531Hypothetical protein; Probable oxidoreductase.
glnP protein networkhttps://string-db.org/network/171101.spr0532ABC transporter membrane-spanning permease - glutamine transport.
glnP-2 protein networkhttps://string-db.org/network/171101.spr0533ABC transporter membrane-spanning permease - glutamine transport.
glnH-2 protein networkhttps://string-db.org/network/171101.spr0534ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor precursor; Belongs to the bacterial solute-binding protein 3 family.
spr0535 protein networkhttps://string-db.org/network/171101.spr0535ABC transporter ATP-binding protein - glutamine, truncation.
spr0536 protein networkhttps://string-db.org/network/171101.spr0536ABC transporter ATP-binding protein - glutamine, truncation.
recJ protein networkhttps://string-db.org/network/171101.spr0537Single-stranded DNA-specific exonuclease, 5'-3'.
rnj-2 protein networkhttps://string-db.org/network/171101.spr0538Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
estA protein networkhttps://string-db.org/network/171101.spr0539Tributyrin esterase.
murM protein networkhttps://string-db.org/network/171101.spr0540Serine/alanine adding enzyme.
murN protein networkhttps://string-db.org/network/171101.spr0541Alanine adding enzyme.
spr0542 protein networkhttps://string-db.org/network/171101.spr0542Hypothetical protein.
uvrC protein networkhttps://string-db.org/network/171101.spr0543Exonuclease ABC - subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsi [...]
spr0544 protein networkhttps://string-db.org/network/171101.spr0544Conserved hypothetical protein.
ABC-SBP-5 protein networkhttps://string-db.org/network/171101.spr0545ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor precursor.
nrd protein networkhttps://string-db.org/network/171101.spr0546Nitroreductase.
pepV protein networkhttps://string-db.org/network/171101.spr0547Dipeptidase.
spr0548 protein networkhttps://string-db.org/network/171101.spr0548Conserved hypothetical protein.
spr0549 protein networkhttps://string-db.org/network/171101.spr0549Hypothetical protein.
spr0550 protein networkhttps://string-db.org/network/171101.spr0550Conserved hypothetical protein.
brnQ protein networkhttps://string-db.org/network/171101.spr0551Branched-chain amino acid transport system carrier protein; Component of the transport system for branched-chain amino acids.
spr0552 protein networkhttps://string-db.org/network/171101.spr0552Conserved hypothetical protein.
spr0553 protein networkhttps://string-db.org/network/171101.spr0553Hypothetical protein.
spr0554 protein networkhttps://string-db.org/network/171101.spr0554Conserved hypothetical protein; Putative carboxypeptidase.
rplK protein networkhttps://string-db.org/network/171101.spr055550S Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
rplA protein networkhttps://string-db.org/network/171101.spr055650S Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
ABC-NBD-6 protein networkhttps://string-db.org/network/171101.spr0557ABC transporter ATP-binding protein - role in polysaccharide efflux.
spr0558 protein networkhttps://string-db.org/network/171101.spr0558Conserved hypothetical protein.
spr0559 protein networkhttps://string-db.org/network/171101.spr0559Conserved hypothetical protein.
spr0560 protein networkhttps://string-db.org/network/171101.spr0560Hypothetical protein.
prtA protein networkhttps://string-db.org/network/171101.spr0561Cell wall-associated serine proteinase precursor PrtA.
PTS-EII-13 protein networkhttps://string-db.org/network/171101.spr0562Phosphotransferase system sugar-specific EII component.
spr0563 protein networkhttps://string-db.org/network/171101.spr0563Hypothetical protein.
PTS-EII-14 protein networkhttps://string-db.org/network/171101.spr0564Phosphotransferase system sugar-specific EII component.
bgaA protein networkhttps://string-db.org/network/171101.spr0565Beta-galactosidase precursor.
spr0566 protein networkhttps://string-db.org/network/171101.spr0566Hypothetical protein.
spr0567 protein networkhttps://string-db.org/network/171101.spr0567Hypothetical protein.
spr0568 protein networkhttps://string-db.org/network/171101.spr0568Hypothetical protein.
spr0569 protein networkhttps://string-db.org/network/171101.spr0569Hypothetical protein.
spr0570 protein networkhttps://string-db.org/network/171101.spr0570Hypothetical protein.
spr0571 protein networkhttps://string-db.org/network/171101.spr0571Conserved hypothetical protein.
spr0572 protein networkhttps://string-db.org/network/171101.spr0572Hypothetical protein.
nha2 protein networkhttps://string-db.org/network/171101.spr0573Na+/H+ antiporter.
spr0574 protein networkhttps://string-db.org/network/171101.spr0574Conserved hypothetical protein.
ccdA protein networkhttps://string-db.org/network/171101.spr0575Cytochrome c-type biogenesis protein.
spr0576 protein networkhttps://string-db.org/network/171101.spr0576Conserved hypothetical protein.
msrA protein networkhttps://string-db.org/network/171101.spr0577Peptide methionine sulfoxide reductase paralog; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of [...]
rr09 protein networkhttps://string-db.org/network/171101.spr0578Response regulator.
hk09 protein networkhttps://string-db.org/network/171101.spr0579Histidine kinase.
spr0580 protein networkhttps://string-db.org/network/171101.spr0580Conserved hypothetical protein; Belongs to the UPF0340 family.
zmpB protein networkhttps://string-db.org/network/171101.spr0581Zinc metalloprotease; Similar to IgA1 protease.
pabB protein networkhttps://string-db.org/network/171101.spr0582Para-aminobenzoate synthetase.
spr0583 protein networkhttps://string-db.org/network/171101.spr0583Hypothetical protein; Similar to 1,4-beta-N-acetylmuramidase.
glcK protein networkhttps://string-db.org/network/171101.spr0584Glucose kinase.
thyA protein networkhttps://string-db.org/network/171101.spr0585Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate ( [...]
spr0586 protein networkhttps://string-db.org/network/171101.spr0586Hypothetical protein.
spr0587 protein networkhttps://string-db.org/network/171101.spr0587Hypothetical protein.
miaA protein networkhttps://string-db.org/network/171101.spr0588tRNA isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formati [...]
hflX protein networkhttps://string-db.org/network/171101.spr0589Conserved hypothetical protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-lik [...]
spr0590 protein networkhttps://string-db.org/network/171101.spr0590Hypothetical protein.
rnz protein networkhttps://string-db.org/network/171101.spr0591Conserved hypothetical protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precurso [...]
spr0592 protein networkhttps://string-db.org/network/171101.spr0592Conserved hypothetical protein; Probable oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
cpsY protein networkhttps://string-db.org/network/171101.spr0593Regulatory function on capsule expression; Belongs to the LysR transcriptional regulatory family.
spr0594 protein networkhttps://string-db.org/network/171101.spr0594Conserved hypothetical protein.
spr0595 protein networkhttps://string-db.org/network/171101.spr0595Conserved hypothetical protein.
spr0596 protein networkhttps://string-db.org/network/171101.spr0596Hypothetical protein.
rsuA-2 protein networkhttps://string-db.org/network/171101.spr0597Ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family.
typA protein networkhttps://string-db.org/network/171101.spr0598GTP-binding protein TypA/BipA (tyrosine phosphorylated protein A).
spr0599 protein networkhttps://string-db.org/network/171101.spr0599Hypothetical protein.
spr0600 protein networkhttps://string-db.org/network/171101.spr0600Conserved hypothetical protein; Putative bacteriocin.
spr0601 protein networkhttps://string-db.org/network/171101.spr0601Conserved hypothetical protein.
ABC-NBD-7 protein networkhttps://string-db.org/network/171101.spr0602ABC transporter ATP-binding protein - sodium transport.
murD protein networkhttps://string-db.org/network/171101.spr0603UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCD [...]
murG protein networkhttps://string-db.org/network/171101.spr0604Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
divIB protein networkhttps://string-db.org/network/171101.spr0605Cell division protein DivIB; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
spr0607 protein networkhttps://string-db.org/network/171101.spr0607Hypothetical protein.
spr0608 protein networkhttps://string-db.org/network/171101.spr0608Hypothetical protein.
spr0609 protein networkhttps://string-db.org/network/171101.spr0609ABC transporter ATP-binding protein - unknown substrate, truncation.
spr0610 protein networkhttps://string-db.org/network/171101.spr0610ABC transporter ATP-binding protein - unknown substrate, truncation.
spr0611 protein networkhttps://string-db.org/network/171101.spr0611Putative membrane spanning protein.
spr0612 protein networkhttps://string-db.org/network/171101.spr0612Degenerate transposase.
pyrF protein networkhttps://string-db.org/network/171101.spr0613Orotidine-5'-decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
pyrE protein networkhttps://string-db.org/network/171101.spr0614Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
spr0615 protein networkhttps://string-db.org/network/171101.spr0615Hypothetical protein.
spr0616 protein networkhttps://string-db.org/network/171101.spr0616Hypothetical protein.
spr0617 protein networkhttps://string-db.org/network/171101.spr0617Hypothetical protein.
spr0618 protein networkhttps://string-db.org/network/171101.spr0618Hypothetical protein.
ABC-NBD-8 protein networkhttps://string-db.org/network/171101.spr0619ABC transporter ATP-binding protein - unknown substrate.
spr0620 protein networkhttps://string-db.org/network/171101.spr0620ABC transporter substrate-binding protein - unknown substrate, truncation.
spr0621 protein networkhttps://string-db.org/network/171101.spr0621ABC transporter substrate-binding protein - unknown substrate, truncation.
glnQ-2 protein networkhttps://string-db.org/network/171101.spr0622ABC transporter ATP-binding protein - glutamine transport.
glnP-3 protein networkhttps://string-db.org/network/171101.spr0623ABC transporter membrane-spanning permease - glutamine transport.
glnP-4 protein networkhttps://string-db.org/network/171101.spr0624ABC transporter membrane-spanning permease - glutamine transport.
spr0625 protein networkhttps://string-db.org/network/171101.spr0625Lactate oxidase, truncation.
lysS protein networkhttps://string-db.org/network/171101.spr0626Lysyl-tRNA synthetase (lysine--tRNA ligase) (LYSRS); Belongs to the class-II aminoacyl-tRNA synthetase family.
lctO protein networkhttps://string-db.org/network/171101.spr0627Lactate oxidase.
spr0628 protein networkhttps://string-db.org/network/171101.spr0628Conserved hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. [...]
thiM protein networkhttps://string-db.org/network/171101.spr0629Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
thiE protein networkhttps://string-db.org/network/171101.spr0630Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine [...]
spr0631 protein networkhttps://string-db.org/network/171101.spr0631Conserved hypothetical protein.
ABC-NBD-9 protein networkhttps://string-db.org/network/171101.spr0632ABC transporter ATP-binding protein - cobalt or other cation transport.
spr0633 protein networkhttps://string-db.org/network/171101.spr0633Conserved hypothetical protein.
tenA protein networkhttps://string-db.org/network/171101.spr0634Transcriptional regulator of extracellular enzyme genes; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a [...]
spr0635 protein networkhttps://string-db.org/network/171101.spr0635Hypothetical protein.
thiM-2 protein networkhttps://string-db.org/network/171101.spr0636Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
thiE-2 protein networkhttps://string-db.org/network/171101.spr0637Thiamine phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamin [...]
thiD protein networkhttps://string-db.org/network/171101.spr0638Phosphomethylpyrimidine kinase.
copY protein networkhttps://string-db.org/network/171101.spr0639COPAB ATPases metal-fist type repressor.
spr0640 protein networkhttps://string-db.org/network/171101.spr0640Conserved hypothetical protein.
ctpA protein networkhttps://string-db.org/network/171101.spr0641P-type ATPase - probable copper transporter.
spxB protein networkhttps://string-db.org/network/171101.spr0642Pyruvate oxidase; Belongs to the TPP enzyme family.
spr0643 protein networkhttps://string-db.org/network/171101.spr0643Hypothetical protein.
Transposase_C protein networkhttps://string-db.org/network/171101.spr0644Degenerate transposase.
spr0645 protein networkhttps://string-db.org/network/171101.spr0645Hypothetical protein.
spr0646 protein networkhttps://string-db.org/network/171101.spr0646Phospho-beta-gluco or galactosidase, truncation; Belongs to the glycosyl hydrolase 1 family.
pmi protein networkhttps://string-db.org/network/171101.spr0647Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family.
NS_transporter protein networkhttps://string-db.org/network/171101.spr0648Sodium-dependent transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
mta protein networkhttps://string-db.org/network/171101.spr0649Regulator of the multidrug efflux pump pmrA.
spr0650 protein networkhttps://string-db.org/network/171101.spr0650Conserved hypothetical protein; Similar to mutator protein MutT; Belongs to the Nudix hydrolase family.
spr0651 protein networkhttps://string-db.org/network/171101.spr0651Conserved hypothetical protein.
spr0652 protein networkhttps://string-db.org/network/171101.spr0652Conserved hypothetical protein; May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
spr0653 protein networkhttps://string-db.org/network/171101.spr0653Conserved hypothetical protein; Probable transcriptional regulator.
comEB protein networkhttps://string-db.org/network/171101.spr0654dCMP deaminase; Putative late competence operon required for DNA binding and uptake.
upp protein networkhttps://string-db.org/network/171101.spr0655Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
clpP protein networkhttps://string-db.org/network/171101.spr0656ATP-dependent CLP protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degrada [...]
spr0657 protein networkhttps://string-db.org/network/171101.spr0657Conserved hypothetical protein.
spr0658 protein networkhttps://string-db.org/network/171101.spr0658Hypothetical protein.
livJ protein networkhttps://string-db.org/network/171101.spr0659ABC transporter substrate-binding protein - branched chain amino acid transport.
livH protein networkhttps://string-db.org/network/171101.spr0660ABC transporter membrane-spanning permease - branched chain amino acid transport; Belongs to the binding-protein-dependent transport system permease family.
livM protein networkhttps://string-db.org/network/171101.spr0661ABC transporter membrane-spanning permease - branched chain amino acid transport; Belongs to the binding-protein-dependent transport system permease family.
livG protein networkhttps://string-db.org/network/171101.spr0662ABC transporter ATP-binding protein - branched chain amino acid transport.
livF protein networkhttps://string-db.org/network/171101.spr0663ABC transporter ATP-binding protein - branched chain amino acid transport.
spr0664 protein networkhttps://string-db.org/network/171101.spr0664Conserved hypothetical protein.
prfB protein networkhttps://string-db.org/network/171101.spr0665Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
ftsE protein networkhttps://string-db.org/network/171101.spr0666ABC transporter ATP-binding protein & cell division protein; Part of the ABC transporter FtsEX involved in cellular division.
ftsX protein networkhttps://string-db.org/network/171101.spr0667Cell division protein FtsX; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein f [...]
ptsG protein networkhttps://string-db.org/network/171101.spr0668PTS glucose-specific enzyme IIABC component.
spr0669 protein networkhttps://string-db.org/network/171101.spr0669Hypothetical protein.
rheB protein networkhttps://string-db.org/network/171101.spr0670ATP-dependent RNA helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.
metK protein networkhttps://string-db.org/network/171101.spr0671S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet forma [...]
pyrDA protein networkhttps://string-db.org/network/171101.spr0672Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
holA protein networkhttps://string-db.org/network/171101.spr0673DNA polymerase III, delta subunit.
sodA protein networkhttps://string-db.org/network/171101.spr0674Manganese co-factored superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. May play a critical role aga [...]
spr0675 protein networkhttps://string-db.org/network/171101.spr0675Hypothetical protein.
rlmN protein networkhttps://string-db.org/network/171101.spr0676Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
spr0677 protein networkhttps://string-db.org/network/171101.spr0677Hypothetical protein.
ABC-NBD-10 protein networkhttps://string-db.org/network/171101.spr0678ABC transporter ATP-binding protein - unknown substrate.
ppiA protein networkhttps://string-db.org/network/171101.spr0679Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophi [...]
spr0680 protein networkhttps://string-db.org/network/171101.spr0680Hypothetical protein.
spr0681 protein networkhttps://string-db.org/network/171101.spr0681Hypothetical protein.
rpsP protein networkhttps://string-db.org/network/171101.spr068230S Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
spr0683 protein networkhttps://string-db.org/network/171101.spr0683Conserved hypothetical protein; Belongs to the UPF0109 family.
spr0684 protein networkhttps://string-db.org/network/171101.spr0684Hypothetical protein.
spr0685 protein networkhttps://string-db.org/network/171101.spr0685Hypothetical protein.
rimM protein networkhttps://string-db.org/network/171101.spr068616S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19 [...]
trmD protein networkhttps://string-db.org/network/171101.spr0687tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
spr0688 protein networkhttps://string-db.org/network/171101.spr0688Hypothetical protein.
spr0689 protein networkhttps://string-db.org/network/171101.spr0689Hypothetical protein.
spr0690 protein networkhttps://string-db.org/network/171101.spr0690Conserved hypothetical protein.
bioY protein networkhttps://string-db.org/network/171101.spr0691Biotin synthase.
gor protein networkhttps://string-db.org/network/171101.spr0692Glutathione oxidoreductase.
spr0693 protein networkhttps://string-db.org/network/171101.spr0693Conserved hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
ABC-NBD-11 protein networkhttps://string-db.org/network/171101.spr0694ABC transporter ATP-binding protein - unknown substrate.
spr0695 protein networkhttps://string-db.org/network/171101.spr0695Conserved hypothetical protein.
metS protein networkhttps://string-db.org/network/171101.spr0696Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the [...]
spr0697 protein networkhttps://string-db.org/network/171101.spr0697Conserved hypothetical protein.
spr0698 protein networkhttps://string-db.org/network/171101.spr0698Conserved hypothetical protein.
spr0699 protein networkhttps://string-db.org/network/171101.spr0699Conserved hypothetical protein.
spr0700 protein networkhttps://string-db.org/network/171101.spr0700Hypothetical protein.
fabG-2 protein networkhttps://string-db.org/network/171101.spr07013-Ketoacyl-ACP reductase.
spr0702 protein networkhttps://string-db.org/network/171101.spr0702Conserved hypothetical protein.
spr0703 protein networkhttps://string-db.org/network/171101.spr0703Hypothetical protein.
spr0704 protein networkhttps://string-db.org/network/171101.spr0704Hypothetical protein.
spr0705 protein networkhttps://string-db.org/network/171101.spr0705Conserved hypothetical protein.
pepN protein networkhttps://string-db.org/network/171101.spr0706Aminopeptidase N.
ciaR protein networkhttps://string-db.org/network/171101.spr0707Response regulator, transcriptional regulatory protein; Member of the two-component regulatory system CiaH/CiaR. Involved in early steps of competence regulation and in penicillin susceptibility.
ciaH protein networkhttps://string-db.org/network/171101.spr0708Sensor protein CiaH histide kinase; Member of the two-component regulatory system CiaH/CiaR. Involved in early steps of competence regulation and in penicillin susceptibility. Probably phosphoryl [...]
spr0709 protein networkhttps://string-db.org/network/171101.spr0709Hypothetical protein.
spr0710 protein networkhttps://string-db.org/network/171101.spr0710Conserved hypothetical protein; Similar to protease.
dinG protein networkhttps://string-db.org/network/171101.spr0711ATP-dependent DNA helicase; 3'-5' exonuclease.
rodA protein networkhttps://string-db.org/network/171101.spr0712Rod shape determining protein; Belongs to the SEDS family.
thiJ protein networkhttps://string-db.org/network/171101.spr07134-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein.
gph-2 protein networkhttps://string-db.org/network/171101.spr0714Phosphoglycolate phosphatase.
gyrB protein networkhttps://string-db.org/network/171101.spr0715DNA gyrase; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwou [...]
ezrA protein networkhttps://string-db.org/network/171101.spr0716Cell division regulator, negative regulator of FtsZ ring formation; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring form [...]
Transposase_C-2 protein networkhttps://string-db.org/network/171101.spr0717Transposase.
Transposase_D protein networkhttps://string-db.org/network/171101.spr0718Transposase.
spr0719 protein networkhttps://string-db.org/network/171101.spr0719Transposase.
spr0720 protein networkhttps://string-db.org/network/171101.spr0720Hypothetical protein.
spr0721 protein networkhttps://string-db.org/network/171101.spr0721Conserved hypothetical protein; Belongs to the Nudix hydrolase family.
Transposase_A-3 protein networkhttps://string-db.org/network/171101.spr0722Transposase.
spr0723 protein networkhttps://string-db.org/network/171101.spr0723Degenerate transposase.
spr0724 protein networkhttps://string-db.org/network/171101.spr0724Degenerate transposase.
clpE protein networkhttps://string-db.org/network/171101.spr0725ATP dependent protease; Belongs to the ClpA/ClpB family.
spr0726 protein networkhttps://string-db.org/network/171101.spr0726Conserved hypothetical protein.
glnP-5 protein networkhttps://string-db.org/network/171101.spr0727ABC transporter membrane-spanning permease - glutamine transport.
glnQ-3 protein networkhttps://string-db.org/network/171101.spr0728ABC transporter ATP-binding protein - glutamine transport.
folD protein networkhttps://string-db.org/network/171101.spr0729Fold bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahy [...]
nnrD protein networkhttps://string-db.org/network/171101.spr0730Conserved hypothetical protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimeri [...]
rpiA protein networkhttps://string-db.org/network/171101.spr0731Ribose-5-phosphate epimerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
deoB protein networkhttps://string-db.org/network/171101.spr0732Phosphodeoxyribomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose.
spr0733 protein networkhttps://string-db.org/network/171101.spr0733Hypothetical protein.
pnp protein networkhttps://string-db.org/network/171101.spr0734Purine nucleoside phosphorylase (inosine phosphorylase); The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside mol [...]
spr0735 protein networkhttps://string-db.org/network/171101.spr0735Hypothetical protein.
spr0736 protein networkhttps://string-db.org/network/171101.spr0736Hypothetical protein.
spr0737 protein networkhttps://string-db.org/network/171101.spr0737Conserved hypothetical protein, truncation; Related to a cytolysin.
deoD protein networkhttps://string-db.org/network/171101.spr0738Purine nucleoside phosphorylase (inosine phosphorylase).
flaR protein networkhttps://string-db.org/network/171101.spr0739Modulates DNA topology.
rpsT protein networkhttps://string-db.org/network/171101.spr074030S Ribosomal protein subunit S20; Binds directly to 16S ribosomal RNA.
coaA protein networkhttps://string-db.org/network/171101.spr0741Pantothenate kinase.
spr0742 protein networkhttps://string-db.org/network/171101.spr0742Hypothetical protein.
spr0743 protein networkhttps://string-db.org/network/171101.spr0743Conserved hypothetical protein.
pdp protein networkhttps://string-db.org/network/171101.spr0744Pyrimidine nucleoside phosphorylase.
deoC protein networkhttps://string-db.org/network/171101.spr0745Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB ald [...]
cdd protein networkhttps://string-db.org/network/171101.spr0746Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
spr0747 protein networkhttps://string-db.org/network/171101.spr0747Conserved hypothetical protein; Similar to basic membrane protein A from Lactococcus lactis subsp. lactis.
ABC-NBD-12 protein networkhttps://string-db.org/network/171101.spr0748ABC transporter ATP-binding protein - ribose/galactose transport.
ABC-MSP-7 protein networkhttps://string-db.org/network/171101.spr0749ABC transporter membrane-spanning permease - ribose/galactose transport; Belongs to the binding-protein-dependent transport system permease family.
ABC-MSP-8 protein networkhttps://string-db.org/network/171101.spr0750ABC transporter membrane-spanning permease - ribose/galactose transport; Belongs to the binding-protein-dependent transport system permease family.
spr0751 protein networkhttps://string-db.org/network/171101.spr0751Degenerate transposase (orf1).
spr0752 protein networkhttps://string-db.org/network/171101.spr0752Degenerate transposase (orf1).
spr0753 protein networkhttps://string-db.org/network/171101.spr0753Degenerate transposase (orf2).
spr0754 protein networkhttps://string-db.org/network/171101.spr0754Degenerate transposase (orf2).
plsY protein networkhttps://string-db.org/network/171101.spr0755Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes ac [...]
parE protein networkhttps://string-db.org/network/171101.spr0756Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DN [...]
parC protein networkhttps://string-db.org/network/171101.spr0757Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DN [...]
ilvE protein networkhttps://string-db.org/network/171101.spr0758Branched-chain-amino-acid transaminase.
spr0759 protein networkhttps://string-db.org/network/171101.spr0759ABC transporter substrate-binding protein - oligopeptid transport, internal deletion.
spr0760 protein networkhttps://string-db.org/network/171101.spr0760Conserved hypothetical protein; Putative integral membrane protein.
spr0761 protein networkhttps://string-db.org/network/171101.spr0761Conserved hypothetical protein; Putative membrane protein.
pcp protein networkhttps://string-db.org/network/171101.spr0762Pyrrolidone-carboxylate peptidase (5-oxoprolyl-peptidase); Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.
spr0763 protein networkhttps://string-db.org/network/171101.spr0763Hypothetical protein.
rpsA protein networkhttps://string-db.org/network/171101.spr076430S Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity); [...]
spr0765 protein networkhttps://string-db.org/network/171101.spr0765Degenerate transposase (orf2).
spr0766 protein networkhttps://string-db.org/network/171101.spr0766Degenerate transposase (orf2).
IS1167-3 protein networkhttps://string-db.org/network/171101.spr0767Transposase (orf1).
spr0768 protein networkhttps://string-db.org/network/171101.spr0768Conserved hypothetical protein.
dnaX protein networkhttps://string-db.org/network/171101.spr0769DNA-directed DNA polymerase III chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' [...]
spr0770 protein networkhttps://string-db.org/network/171101.spr0770Hypothetical protein.
ABC-NBD-13 protein networkhttps://string-db.org/network/171101.spr0771ABC transporter ATP-binding protein - unknown substrate.
spr0772 protein networkhttps://string-db.org/network/171101.spr0772Conserved hypothetical protein.
spr0773 protein networkhttps://string-db.org/network/171101.spr0773Conserved hypothetical protein; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
nifU protein networkhttps://string-db.org/network/171101.spr0774NifU protein.
spr0775 protein networkhttps://string-db.org/network/171101.spr0775Conserved hypothetical protein.
dacA protein networkhttps://string-db.org/network/171101.spr0776D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
spr0777 protein networkhttps://string-db.org/network/171101.spr0777Conserved hypothetical protein; Putative permease.
fruR protein networkhttps://string-db.org/network/171101.spr0778Transcriptional repressor of the fructose operon.
fruB protein networkhttps://string-db.org/network/171101.spr0779Fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
fruA protein networkhttps://string-db.org/network/171101.spr0780Fructose specific-phosphotransferase system IIBC component.
ftsK protein networkhttps://string-db.org/network/171101.spr0781Cell division protein; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-term [...]
spr0782 protein networkhttps://string-db.org/network/171101.spr0782Hypothetical protein.
spr0783 protein networkhttps://string-db.org/network/171101.spr0783Probable pyridoxal-phosphate dependent aminotransferase.
thiI protein networkhttps://string-db.org/network/171101.spr0784Thiamin biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes th [...]
spr0785 protein networkhttps://string-db.org/network/171101.spr0785Hypothetical protein.
spr0786 protein networkhttps://string-db.org/network/171101.spr0786Hypothetical protein.
spr0787 protein networkhttps://string-db.org/network/171101.spr0787Hypothetical protein.
spr0788 protein networkhttps://string-db.org/network/171101.spr0788Hypothetical protein.
spr0789 protein networkhttps://string-db.org/network/171101.spr0789Hypothetical protein.
hsdM-2 protein networkhttps://string-db.org/network/171101.spr0790Type I restriction modification enzyme methylase subunit.
hsdS-4 protein networkhttps://string-db.org/network/171101.spr0791Type I restriction-modification enzyme 1, S subunit.
hsdR-2 protein networkhttps://string-db.org/network/171101.spr0792Type 1 restriction modification system endonuclease R.
argR protein networkhttps://string-db.org/network/171101.spr0793Arginine repressor; Regulates arginine biosynthesis genes.
pepXP protein networkhttps://string-db.org/network/171101.spr0794Xaa-pro dipeptidyl-peptidase; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidas [...]
dnaE protein networkhttps://string-db.org/network/171101.spr0795DNA-polymerase III alpha-chain.
pfkA protein networkhttps://string-db.org/network/171101.spr07966-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
pykF protein networkhttps://string-db.org/network/171101.spr0797Pyruvate kinase I; fructose-stimulated.
spr0798 protein networkhttps://string-db.org/network/171101.spr0798Hypothetical protein.
spr0799 protein networkhttps://string-db.org/network/171101.spr0799Hypothetical protein.
spr0800 protein networkhttps://string-db.org/network/171101.spr0800Hypothetical protein.
spr0801 protein networkhttps://string-db.org/network/171101.spr0801Degenerate transposase (orf1).
spr0802 protein networkhttps://string-db.org/network/171101.spr0802Hypothetical protein.
spr0803 protein networkhttps://string-db.org/network/171101.spr0803Hypothetical protein.
spr0804 protein networkhttps://string-db.org/network/171101.spr0804Conserved hypothetical protein.
spr0805 protein networkhttps://string-db.org/network/171101.spr0805Conserved hypothetical protein.
spr0806 protein networkhttps://string-db.org/network/171101.spr0806Hypothetical protein.
spr0807 protein networkhttps://string-db.org/network/171101.spr0807Conserved hypothetical protein.
tex protein networkhttps://string-db.org/network/171101.spr0808Toxin expression - transcriptional accessory protein.
spr0809 protein networkhttps://string-db.org/network/171101.spr0809Conserved hypothetical protein; Belongs to the SprT family.
spr0810 protein networkhttps://string-db.org/network/171101.spr0810Hypothetical protein.
ABC-NBD-14 protein networkhttps://string-db.org/network/171101.spr0812ABC transporter ATP-binding protein - unknown substrate.
ABC-MSD-3 protein networkhttps://string-db.org/network/171101.spr0813ABC transporter membrane-spanning permease - unknown substrate.
spr0814 protein networkhttps://string-db.org/network/171101.spr0814Conserved hypothetical protein.
spr0815 protein networkhttps://string-db.org/network/171101.spr0815Degenerate transposase.
cad protein networkhttps://string-db.org/network/171101.spr0816Lysine decarboxylase.
spr0817 protein networkhttps://string-db.org/network/171101.spr0817Degenerate transposase.
spr0818 protein networkhttps://string-db.org/network/171101.spr0818Degenerate transposase.
speE protein networkhttps://string-db.org/network/171101.spr0819Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermid [...]
spr0820 protein networkhttps://string-db.org/network/171101.spr0820Conserved hypothetical protein.
nspC protein networkhttps://string-db.org/network/171101.spr0821Carboxynorspermidine decarboxylase.
aguA protein networkhttps://string-db.org/network/171101.spr0822Conserved hypothetical protein.
but protein networkhttps://string-db.org/network/171101.spr0823Beta-alanine synthase or beta-ureidopropionase.
spr0824 protein networkhttps://string-db.org/network/171101.spr0824Conserved hypothetical protein.
spr0825 protein networkhttps://string-db.org/network/171101.spr0825Hypothetical protein.
spr0826 protein networkhttps://string-db.org/network/171101.spr0826Hypothetical protein.
spr0827 protein networkhttps://string-db.org/network/171101.spr0827Hypothetical protein.
cpsY-2 protein networkhttps://string-db.org/network/171101.spr0828Regulatory function on capsule expression in group B streptococci; Belongs to the LysR transcriptional regulatory family.
lspA protein networkhttps://string-db.org/network/171101.spr0829Signal peptidase type II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
rluD protein networkhttps://string-db.org/network/171101.spr083023S rRNA pseudouridine synthase (supresses ftsH(ts) mutants); Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
lytD protein networkhttps://string-db.org/network/171101.spr0831Teichoic acid phosphorylcholine esterase/choline binding protein E (cbpE).
proB protein networkhttps://string-db.org/network/171101.spr0832Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
proA protein networkhttps://string-db.org/network/171101.spr0833Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclizat [...]
proC protein networkhttps://string-db.org/network/171101.spr0834Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
tmk protein networkhttps://string-db.org/network/171101.spr0835Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
holB protein networkhttps://string-db.org/network/171101.spr0836DNA polymerase III, delta' subunit.
spr0837 protein networkhttps://string-db.org/network/171101.spr0837Conserved hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family.
rsmI protein networkhttps://string-db.org/network/171101.spr0838Conserved hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
spr0839 protein networkhttps://string-db.org/network/171101.spr0839Conserved hypothetical protein.
spr0840 protein networkhttps://string-db.org/network/171101.spr0840Hypothetical protein.
IS1381 protein networkhttps://string-db.org/network/171101.spr0841Tranposase (orf2).
IS1381-2 protein networkhttps://string-db.org/network/171101.spr0842Tranposase (orf1).
spr0843 protein networkhttps://string-db.org/network/171101.spr0843Hypothetical protein.
gidA-2 protein networkhttps://string-db.org/network/171101.spr0844Glucose inhibited division protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.
pyrH protein networkhttps://string-db.org/network/171101.spr0845UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
frr protein networkhttps://string-db.org/network/171101.spr0846Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
spr0847 protein networkhttps://string-db.org/network/171101.spr0847Conserved hypothetical protein; Belongs to the CvfB family.
spr0848 protein networkhttps://string-db.org/network/171101.spr0848Conserved hypothetical protein; Belongs to the UPF0346 family.
phoL protein networkhttps://string-db.org/network/171101.spr0849PhoH-like protein.
spr0850 protein networkhttps://string-db.org/network/171101.spr0850Hypothetical protein.
spr0851 protein networkhttps://string-db.org/network/171101.spr0851Hypothetical protein.
spr0852 protein networkhttps://string-db.org/network/171101.spr0852Alanine dehydrogenase, truncation.
spr0853 protein networkhttps://string-db.org/network/171101.spr0853Alanine dehydrogenase, truncation.
spr0854 protein networkhttps://string-db.org/network/171101.spr0854Alanine dehydrogenase, truncation.
spr0855 protein networkhttps://string-db.org/network/171101.spr0855Conserved hypothetical protein; Probable acetyl transferase.
celA protein networkhttps://string-db.org/network/171101.spr0856Competence induced; comE-like protein A also known as CilE; Putative DNA uptake by homology.
celB protein networkhttps://string-db.org/network/171101.spr0857Competence induced; comE-like protein B; Putative DNA uptake by homology.
spr0858 protein networkhttps://string-db.org/network/171101.spr0858Hypothetical protein.
spr0859 protein networkhttps://string-db.org/network/171101.spr0859Hypothetical protein.
spr0860 protein networkhttps://string-db.org/network/171101.spr0860Hypothetical protein.
infC protein networkhttps://string-db.org/network/171101.spr0861Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enha [...]
rpmI protein networkhttps://string-db.org/network/171101.spr086250S Ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
rplT protein networkhttps://string-db.org/network/171101.spr086350S Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing func [...]
lguL protein networkhttps://string-db.org/network/171101.spr0864Lactoylglutathione lyase.
pyrDII protein networkhttps://string-db.org/network/171101.spr0865Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the u [...]
pyrD protein networkhttps://string-db.org/network/171101.spr0866Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
lytB protein networkhttps://string-db.org/network/171101.spr0867Endo-beta-N-acetylglucosaminidase; Plays an important role in cell wall degradation and cell separation.
flpA protein networkhttps://string-db.org/network/171101.spr0868Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subu [...]
ybeY protein networkhttps://string-db.org/network/171101.spr0869Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
dgkA protein networkhttps://string-db.org/network/171101.spr0870Diacylglycerol kinase.
era protein networkhttps://string-db.org/network/171101.spr0871GTPase/GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly [...]
mutM protein networkhttps://string-db.org/network/171101.spr0872Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a [...]
coaE protein networkhttps://string-db.org/network/171101.spr0873Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
spr0874 protein networkhttps://string-db.org/network/171101.spr0874Hypothetical protein.
pmrA protein networkhttps://string-db.org/network/171101.spr0875Major facilitator superfamily multi-drug resistance efflux pump; Efflux pump for various substrates; Belongs to the major facilitator superfamily. TCR/Tet family.
rpmG protein networkhttps://string-db.org/network/171101.spr087650S Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
secG protein networkhttps://string-db.org/network/171101.spr0877Protein-export membrane protein secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
rnr protein networkhttps://string-db.org/network/171101.spr0878Exoribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
smpB protein networkhttps://string-db.org/network/171101.spr0879Small protein B; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA a [...]
tehB protein networkhttps://string-db.org/network/171101.spr0880Tellurite resistance.
coiA protein networkhttps://string-db.org/network/171101.spr0881Competence induced protein A.
pepB protein networkhttps://string-db.org/network/171101.spr0882Group B oligopeptidase.
spr0883 protein networkhttps://string-db.org/network/171101.spr0883Conserved hypothetical protein; Probable methyltransferase.
ppmA protein networkhttps://string-db.org/network/171101.spr0884Proteinase maturation protein; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.
spr0885 protein networkhttps://string-db.org/network/171101.spr0885Degenerate transposase (orf2).
spr0886 protein networkhttps://string-db.org/network/171101.spr0886Degenerate transposase (orf1).
gpmB-2 protein networkhttps://string-db.org/network/171101.spr0887Phosphoglycerate mutase.
ebsC protein networkhttps://string-db.org/network/171101.spr0888Regulatory protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.
spr0889 protein networkhttps://string-db.org/network/171101.spr0889Conserved hypothetical protein.
spr0890 protein networkhttps://string-db.org/network/171101.spr0890Hypothetical protein.
gcaD protein networkhttps://string-db.org/network/171101.spr0891UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyz [...]
spr0892 protein networkhttps://string-db.org/network/171101.spr0892Conserved hypothetical protein.
spr0893 protein networkhttps://string-db.org/network/171101.spr0893Hypothetical protein.
pfs protein networkhttps://string-db.org/network/171101.spr08945'-methylthioadenosine / S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHc [...]
spr0895 protein networkhttps://string-db.org/network/171101.spr0895Conserved hypothetical protein.
dnaQ protein networkhttps://string-db.org/network/171101.spr0896DNA polymerase III, epsilon chain.
spr0897 protein networkhttps://string-db.org/network/171101.spr0897Hypothetical protein.
spr0898 protein networkhttps://string-db.org/network/171101.spr0898Degenerative transposase.
spr0899 protein networkhttps://string-db.org/network/171101.spr0899Degenerate transposase.
spr0900 protein networkhttps://string-db.org/network/171101.spr0900Hypothetical protein.
spr0901 protein networkhttps://string-db.org/network/171101.spr0901Hypothetical protein.
spr0902 protein networkhttps://string-db.org/network/171101.spr0902Hypothetical protein.
ccdA-2 protein networkhttps://string-db.org/network/171101.spr0903Cytochrome c-type biogenesis protein.
spr0904 protein networkhttps://string-db.org/network/171101.spr0904Conserved hypothetical protein; Similar to thiol:disulfide interchange protein.
yfnA protein networkhttps://string-db.org/network/171101.spr0905Cationic amino acid transporter - APC Superfamily.
lmb protein networkhttps://string-db.org/network/171101.spr0906Lipoprotein; Belongs to the bacterial solute-binding protein 9 family.
phtD protein networkhttps://string-db.org/network/171101.spr0907Pneumococcal histidine triad protein D precursor.
phtE protein networkhttps://string-db.org/network/171101.spr0908Pneumococcal histidine triad protein E precursor.
spr0909 protein networkhttps://string-db.org/network/171101.spr0909Hypothetical protein.
spr0910 protein networkhttps://string-db.org/network/171101.spr0910Pneumococcal histidine triad protein E precursor, truncation.
spr0911 protein networkhttps://string-db.org/network/171101.spr0911Hypothetical protein.
spr0912 protein networkhttps://string-db.org/network/171101.spr0912Hypothetical protein.
pepT protein networkhttps://string-db.org/network/171101.spr0913Aminotripeptidase; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
hemH protein networkhttps://string-db.org/network/171101.spr0914Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
mscL protein networkhttps://string-db.org/network/171101.spr0915Large conductance mechano-sensitive ion channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes with [...]
mesH protein networkhttps://string-db.org/network/171101.spr0916MesH protein.
ccl protein networkhttps://string-db.org/network/171101.spr0917Citrulline cluster-linked gene.
asd protein networkhttps://string-db.org/network/171101.spr0918Aspartate beta-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to t [...]
dapA protein networkhttps://string-db.org/network/171101.spr0919Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
thdF protein networkhttps://string-db.org/network/171101.spr0920Thiophene and furan oxidation protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of c [...]
xylH protein networkhttps://string-db.org/network/171101.spr09214-oxalocrotonate tautomerase.
tdk protein networkhttps://string-db.org/network/171101.spr0922Thymidine kinase.
bltD protein networkhttps://string-db.org/network/171101.spr0923Spermine/spermidine acetyltransferase.
prfA protein networkhttps://string-db.org/network/171101.spr0924Peptide chain release factor I; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
hemK protein networkhttps://string-db.org/network/171101.spr0925HemK protein homolog; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein [...]
spr0926 protein networkhttps://string-db.org/network/171101.spr0926Conserved hypothetical protein; Belongs to the SUA5 family.
spr0927 protein networkhttps://string-db.org/network/171101.spr0927Conserved hypothetical protein.
glyA protein networkhttps://string-db.org/network/171101.spr0928Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
spr0929 protein networkhttps://string-db.org/network/171101.spr0929Hypothetical protein.
pvaA protein networkhttps://string-db.org/network/171101.spr0930Conserved hypothetical protein; Putative RAS-related protein.
spr0931 protein networkhttps://string-db.org/network/171101.spr0931Conserved hypothetical protein.
spr0932 protein networkhttps://string-db.org/network/171101.spr0932Conserved hypothetical protein; Similar to RNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
spr0933 protein networkhttps://string-db.org/network/171101.spr0933Hypothetical protein.
ABC-SBP-6 protein networkhttps://string-db.org/network/171101.spr0934ABC transporter substrate-binding protein - iron transport.
ABC-MSP-9 protein networkhttps://string-db.org/network/171101.spr0935ABC transporter membrane-spanning permease - iron transport; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
ABC-MSP-10 protein networkhttps://string-db.org/network/171101.spr0936ABC transporter membrane-spanning permease - iron transport; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
ABC-NBD-15 protein networkhttps://string-db.org/network/171101.spr0938ABC transporter ATP-binding protein - iron transport.
spr0939 protein networkhttps://string-db.org/network/171101.spr0939Hypothetical protein.
spr0940 protein networkhttps://string-db.org/network/171101.spr0940Hypothetical protein.
spr0941 protein networkhttps://string-db.org/network/171101.spr0941Hypothetical protein.
ccrB protein networkhttps://string-db.org/network/171101.spr0942Low similarity to site-specific recombinase.
spr0943 protein networkhttps://string-db.org/network/171101.spr0943Hypothetical protein.
spr0944 protein networkhttps://string-db.org/network/171101.spr0944Hypothetical protein.
spr0945 protein networkhttps://string-db.org/network/171101.spr0945Hypothetical protein.
spr0946 protein networkhttps://string-db.org/network/171101.spr0946Conserved hypothetical protein; Putative hydrolase.
spr0947 protein networkhttps://string-db.org/network/171101.spr0947Conserved hypothetical protein.
nplT protein networkhttps://string-db.org/network/171101.spr0948Neopullulanase; Belongs to the glycosyl hydrolase 13 family.
spr0949 protein networkhttps://string-db.org/network/171101.spr0949Hypothetical protein.
spr0950 protein networkhttps://string-db.org/network/171101.spr0950Hypothetical protein.
spr0951 protein networkhttps://string-db.org/network/171101.spr0951Hypothetical protein.
spr0952 protein networkhttps://string-db.org/network/171101.spr0952Conserved hypothetical protein.
spr0953 protein networkhttps://string-db.org/network/171101.spr0953Hypothetical protein.
spr0954 protein networkhttps://string-db.org/network/171101.spr0954Hypothetical protein.
spr0955 protein networkhttps://string-db.org/network/171101.spr0955Hypothetical protein in TN5252.
spr0956 protein networkhttps://string-db.org/network/171101.spr0956Hypothetical protein.
spr0957 protein networkhttps://string-db.org/network/171101.spr0957Tn5252, relaxase, truncation.
spr0958 protein networkhttps://string-db.org/network/171101.spr0958Tn5252, relaxase, truncation.
spr0959 protein networkhttps://string-db.org/network/171101.spr0959Hypothetical protein.
mutR-2 protein networkhttps://string-db.org/network/171101.spr0960Similar to positive transcriptional regulator MutR.
rffD protein networkhttps://string-db.org/network/171101.spr0961UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
spr0962 protein networkhttps://string-db.org/network/171101.spr0962Conserved hypothetical protein.
spr0963 protein networkhttps://string-db.org/network/171101.spr0963Hypothetical protein.
spr0964 protein networkhttps://string-db.org/network/171101.spr0964Hypothetical protein.
spr0965 protein networkhttps://string-db.org/network/171101.spr0965Hypothetical protein.
spr0966 protein networkhttps://string-db.org/network/171101.spr0966Conserved hypothetical protein; Probable acid-CoA ligase.
spr0967 protein networkhttps://string-db.org/network/171101.spr0967Conserved hypothetical protein.
spr0968 protein networkhttps://string-db.org/network/171101.spr0968Hypothetical protein.
nikS protein networkhttps://string-db.org/network/171101.spr0969Nikkomycin biosynthesis protein, carboxylase.
spr0970 protein networkhttps://string-db.org/network/171101.spr0970Conserved hypothetical protein; Probable acetyltransferase.
mefE protein networkhttps://string-db.org/network/171101.spr0971ABC transporter membrane-spanning permease - macrolide efflux.
spr0972 protein networkhttps://string-db.org/network/171101.spr0972Conserved hypothetical protein; Putative repressor protein.
ftsW protein networkhttps://string-db.org/network/171101.spr0973Cell division protein FtsW; Belongs to the SEDS family.
ppc protein networkhttps://string-db.org/network/171101.spr0974Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
ABC-SBP-7 protein networkhttps://string-db.org/network/171101.spr0975ABC transporter substrate-binding protein - unknown substrate.
ABC-MSP-11 protein networkhttps://string-db.org/network/171101.spr0976ABC transporter membrane-spanning permease - unknown substrate; Belongs to the binding-protein-dependent transport system permease family.
ABC-NBD-16 protein networkhttps://string-db.org/network/171101.spr0977ABC transporter ATP-binding protein - unknown substrate.
dnaG protein networkhttps://string-db.org/network/171101.spr0978DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpoD protein networkhttps://string-db.org/network/171101.spr0979RNA polymerase sigmA FACTOR 70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the pri [...]
spr0980 protein networkhttps://string-db.org/network/171101.spr0980Conserved hypothetical protein.
cpoA protein networkhttps://string-db.org/network/171101.spr0981Glycosyltransferase; Galactosyltransferase involved in the biosynthesis of the bilayer-forming membrane lipid alpha-galactosyl-glucosyldiacylglycerol which is involved in maintaining constant non [...]
spr0982 protein networkhttps://string-db.org/network/171101.spr0982Conserved Hypothetical protein; Glucosyltransferase involved in the biosynthesis of the non- bilayer-prone membrane lipid alpha-monoglucosyldiacylglycerol. This is a major component for maintaini [...]
spr0983 protein networkhttps://string-db.org/network/171101.spr0983Hypothetical protein.
obg protein networkhttps://string-db.org/network/171101.spr0984GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role [...]
spr0985 protein networkhttps://string-db.org/network/171101.spr0985Hypothetical protein.
spr0986 protein networkhttps://string-db.org/network/171101.spr0986Degenerate transposase (orf2).
spr0987 protein networkhttps://string-db.org/network/171101.spr0987Degenerate transposase (orf2).
IS1167-4 protein networkhttps://string-db.org/network/171101.spr0988Transposase (orf1).
murZ protein networkhttps://string-db.org/network/171101.spr0989UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
spr0990 protein networkhttps://string-db.org/network/171101.spr0990Conserved hypothetical protein; Similar to alanine acetyl transferase.
spr0991 protein networkhttps://string-db.org/network/171101.spr0991Conserved hypothetical protein.
map protein networkhttps://string-db.org/network/171101.spr0992Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharg [...]
spr0993 protein networkhttps://string-db.org/network/171101.spr0993Degenerate transposase (orf1).
IS1381-3 protein networkhttps://string-db.org/network/171101.spr0994Tranposase (orf2).
pcrA protein networkhttps://string-db.org/network/171101.spr0995ATP-dependent DNA helicase.
radC protein networkhttps://string-db.org/network/171101.spr0996DNA repair protein.
spr0997 protein networkhttps://string-db.org/network/171101.spr0997Conserved hypothetical protein; Probable amidotransferase.
rex protein networkhttps://string-db.org/network/171101.spr0998Conserved hypothetical protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
spr0999 protein networkhttps://string-db.org/network/171101.spr0999Hypothetical protein.
spr1000 protein networkhttps://string-db.org/network/171101.spr1000Hypothetical protein.
nifS protein networkhttps://string-db.org/network/171101.spr1001Pyridoxal-phosphate dependent aminotransferase.
prs protein networkhttps://string-db.org/network/171101.spr1002Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hy [...]
spr1003 protein networkhttps://string-db.org/network/171101.spr1003Conserved hypothetical protein.
spr1004 protein networkhttps://string-db.org/network/171101.spr1004Similar to GTP pyrophosphokinase.
nadK protein networkhttps://string-db.org/network/171101.spr1005Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylatio [...]
rluD-2 protein networkhttps://string-db.org/network/171101.spr100623S rRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
pta protein networkhttps://string-db.org/network/171101.spr1007Phosphate acetyltransferase.
spr1008 protein networkhttps://string-db.org/network/171101.spr1008Degenerate transposase (orf2).
IS1167-5 protein networkhttps://string-db.org/network/171101.spr1009Transposase (orf1).
spr1010 protein networkhttps://string-db.org/network/171101.spr1010Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
spr1011 protein networkhttps://string-db.org/network/171101.spr1011Conserved hypothetical protein.
rplU protein networkhttps://string-db.org/network/171101.spr101250S Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
spr1013 protein networkhttps://string-db.org/network/171101.spr1013Conserved hypothetical protein.
rpmA protein networkhttps://string-db.org/network/171101.spr101450S Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
spr1015 protein networkhttps://string-db.org/network/171101.spr1015Hypothetical protein.
spr1016 protein networkhttps://string-db.org/network/171101.spr1016Hypothetical protein.
mreA protein networkhttps://string-db.org/network/171101.spr1017Macrolide-efflux protein; Belongs to the ribF family.
spr1018 protein networkhttps://string-db.org/network/171101.spr1018Conserved hypothetical protein.
spr1019 protein networkhttps://string-db.org/network/171101.spr1019Conserved hypothetical protein; May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
hlpA protein networkhttps://string-db.org/network/171101.spr1020Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
ABC-NBD-17 protein networkhttps://string-db.org/network/171101.spr1021ABC transporter ATP-binding protein - unknown substrate.
rggD protein networkhttps://string-db.org/network/171101.spr1022Transcriptional regulator.
ABC-MSP-12 protein networkhttps://string-db.org/network/171101.spr1023ABC transporter membrane-spanning permease - macrolide efflux.
ligA protein networkhttps://string-db.org/network/171101.spr1024DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy sourc [...]
pulI protein networkhttps://string-db.org/network/171101.spr1025Thermostable pullulanase; Belongs to the glycosyl hydrolase 13 family.
spr1026 protein networkhttps://string-db.org/network/171101.spr1026Hypothetical protein.
spr1027 protein networkhttps://string-db.org/network/171101.spr1027Hypothetical protein.
gapN protein networkhttps://string-db.org/network/171101.spr1028NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
glgB protein networkhttps://string-db.org/network/171101.spr10291,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains [...]
glgC protein networkhttps://string-db.org/network/171101.spr1030Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between AT [...]
glgD protein networkhttps://string-db.org/network/171101.spr1031Required for glycogen biosynthesis.
glgA protein networkhttps://string-db.org/network/171101.spr1032Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
spr1033 protein networkhttps://string-db.org/network/171101.spr1033Phosphoserine phosphatase, truncation.
glxK protein networkhttps://string-db.org/network/171101.spr1034Glycerate kinase; Belongs to the glycerate kinase type-1 family.
spr1035 protein networkhttps://string-db.org/network/171101.spr1035Hypothetical protein.
eno protein networkhttps://string-db.org/network/171101.spr1036Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
spr1037 protein networkhttps://string-db.org/network/171101.spr1037Transposase.
Transposase_A-4 protein networkhttps://string-db.org/network/171101.spr1038Transposase.
rexB protein networkhttps://string-db.org/network/171101.spr1039Second subunit of major exonuclease; The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generatin [...]
rexA protein networkhttps://string-db.org/network/171101.spr1040First subunit of major exonuclease; The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating [...]
spr1041 protein networkhttps://string-db.org/network/171101.spr1041Hypothetical protein.
iga protein networkhttps://string-db.org/network/171101.spr1042Immunoglobulin A1 protease; Zinc metalloproteinase which cleaves human immunoglobulin A1 (IgA1) in the hinge region.
RbgA protein networkhttps://string-db.org/network/171101.spr1043Conserved hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
rnh protein networkhttps://string-db.org/network/171101.spr1044Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
spr1045 protein networkhttps://string-db.org/network/171101.spr1045Conserved hypothetical protein; Putative channel transporter.
xerC protein networkhttps://string-db.org/network/171101.spr1046Integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromo [...]
lplA protein networkhttps://string-db.org/network/171101.spr1047Lipoate protein ligase A.
acoL protein networkhttps://string-db.org/network/171101.spr1048Dihydrolipoamide dehydrogenase.
acoC protein networkhttps://string-db.org/network/171101.spr1049Dihydrolipoamide S-acetyltransferase.
acoB protein networkhttps://string-db.org/network/171101.spr1050TPP-dependent acetoin dehydrogenase beta chain.
acoA protein networkhttps://string-db.org/network/171101.spr1051TPP-dependent acetoin dehydrogenase alpha chain.
norM protein networkhttps://string-db.org/network/171101.spr1052Conserved hypothetical protein; Multidrug efflux pump; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
pyrC protein networkhttps://string-db.org/network/171101.spr1053Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
mutX protein networkhttps://string-db.org/network/171101.spr10548-oxodGTP nucleoside triphosphatase; Involved in the DNA repair system to avoid A.T to G.C transversions. Degrades 8-oxo-dGTP to the monophosphate, but is also active on all of the nucleoside tri [...]
ung protein networkhttps://string-db.org/network/171101.spr1055DNA-uracil glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
spr1056 protein networkhttps://string-db.org/network/171101.spr1056Hypothetical protein.
spr1057 protein networkhttps://string-db.org/network/171101.spr1057Conserved hypothetical protein.
spr1058 protein networkhttps://string-db.org/network/171101.spr1058Hypothetical protein.
spr1059 protein networkhttps://string-db.org/network/171101.spr1059Hypothetical protein.
phpA protein networkhttps://string-db.org/network/171101.spr1060Histidine Motif-Containing protein.
phtA protein networkhttps://string-db.org/network/171101.spr1061Pneumococcal histidine triad protein A precursor.
ptsI protein networkhttps://string-db.org/network/171101.spr1062PTS enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes th [...]
ptsH protein networkhttps://string-db.org/network/171101.spr1063Histidine-containing phosphocarrier protein of the PTS.
nrdH protein networkhttps://string-db.org/network/171101.spr1064Glutaredoxin-like protein involved in electron transport system for ribonucleotide reductase system NrdEF.
nrdE protein networkhttps://string-db.org/network/171101.spr1065Ribonucleoside-diphosphate reductase (major subunit); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotide [...]
nrdF protein networkhttps://string-db.org/network/171101.spr1066Nonessential ribonucleoside-diP reductase 2, subunit beta, class I, function unknown; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from [...]
lacR protein networkhttps://string-db.org/network/171101.spr1067Lactose phosphotransferase system repressor.
lacG-2 protein networkhttps://string-db.org/network/171101.spr1069Phospho-beta-D-galactosidase; Belongs to the glycosyl hydrolase 1 family.
lacE protein networkhttps://string-db.org/network/171101.spr1070PTS system, lactose-specific IIBC component.
lacF protein networkhttps://string-db.org/network/171101.spr1071PTS system, lactose-specific IIA component.
lacT protein networkhttps://string-db.org/network/171101.spr1072Antiterminator protein.
lacD protein networkhttps://string-db.org/network/171101.spr1073Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family.
lacC protein networkhttps://string-db.org/network/171101.spr1074Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
lacB protein networkhttps://string-db.org/network/171101.spr1075Galactose-6-phosphate isomerase LacB subunit.
lacA protein networkhttps://string-db.org/network/171101.spr1076Galactose-6-phosphate isomerase LacA subunit.
spr1077 protein networkhttps://string-db.org/network/171101.spr1077Function unknown, truncation.
spr1078 protein networkhttps://string-db.org/network/171101.spr1078Degenerate transposase (orf2).
spr1079 protein networkhttps://string-db.org/network/171101.spr1079Degenerate transposase (orf1).
spr1080 protein networkhttps://string-db.org/network/171101.spr1080Hypothetical protein.
spr1081 protein networkhttps://string-db.org/network/171101.spr1081Hypothetical protein.
lepA protein networkhttps://string-db.org/network/171101.spr1082GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codo [...]
pphA protein networkhttps://string-db.org/network/171101.spr1083Serine/threonine protein phosphatase.
recN protein networkhttps://string-db.org/network/171101.spr1084DNA repair and genetic recombination; May be involved in recombinational repair of damaged DNA.
ahrC protein networkhttps://string-db.org/network/171101.spr1085Transcriptional regulator of arginine metabolism expression; Regulates arginine biosynthesis genes.
spr1086 protein networkhttps://string-db.org/network/171101.spr1086Conserved hypothetical protein; Hemolysin-like protein.
ispA protein networkhttps://string-db.org/network/171101.spr1087Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
xseB protein networkhttps://string-db.org/network/171101.spr1088Exodeoxyribonuclease small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleoti [...]
xseA protein networkhttps://string-db.org/network/171101.spr1089Exodeoxyribonuclease large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleoti [...]
udK protein networkhttps://string-db.org/network/171101.spr1090Uridine kinase.
spr1091 protein networkhttps://string-db.org/network/171101.spr1091Hypothetical protein.
truB protein networkhttps://string-db.org/network/171101.spr1092tRNA pseudouridine 5S synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
spr1093 protein networkhttps://string-db.org/network/171101.spr1093Conserved hypothetical protein.
spr1094 protein networkhttps://string-db.org/network/171101.spr1094Conserved hypothetical protein.
spr1095 protein networkhttps://string-db.org/network/171101.spr1095O-acetylhomoserine sulfhydrylase, truncation.
spr1096 protein networkhttps://string-db.org/network/171101.spr1096O-acetylhomoserine sulfhydrylase, truncation.
nirC protein networkhttps://string-db.org/network/171101.spr1097Formate-nitrate transporter.
srtA protein networkhttps://string-db.org/network/171101.spr1098Sortase; Putative, proposed to perform the peptide cleavage and the transpeptidation during the process of anchoring proteins to Gram-positive bacterial cell walls.
gyrA protein networkhttps://string-db.org/network/171101.spr1099DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
ldh protein networkhttps://string-db.org/network/171101.spr1100L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
spr1101 protein networkhttps://string-db.org/network/171101.spr1101Uncharacterized restriction enzyme, interrupted-C.
spr1102 protein networkhttps://string-db.org/network/171101.spr1102Uncharacterized restriction enzyme, interrupted-N.
spr1103 protein networkhttps://string-db.org/network/171101.spr1103Hypothetical protein.
spr1104 protein networkhttps://string-db.org/network/171101.spr1104Hypothetical protein.
vicX protein networkhttps://string-db.org/network/171101.spr1105VicX protein.
hk02 protein networkhttps://string-db.org/network/171101.spr1106Histidine kinase.
rr02 protein networkhttps://string-db.org/network/171101.spr1107Response regulator.
mutY protein networkhttps://string-db.org/network/171101.spr1108Similar to A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
fhs protein networkhttps://string-db.org/network/171101.spr1109Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
dfp protein networkhttps://string-db.org/network/171101.spr1110Similar to C-terminal region of the Dfp protein.
dfp-2 protein networkhttps://string-db.org/network/171101.spr1111Similar to N-terminal region of the Dfp protein.
spr1112 protein networkhttps://string-db.org/network/171101.spr1112Conserved hypothetical protein; Probable membrane protein.
spr1113 protein networkhttps://string-db.org/network/171101.spr1113Hypothetical protein.
spr1114 protein networkhttps://string-db.org/network/171101.spr1114Conserved hypothetical protein; Probable transcriptional regulator.
spr1115 protein networkhttps://string-db.org/network/171101.spr1115Conserved hypothetical protein; MutT-like protein.
spr1116 protein networkhttps://string-db.org/network/171101.spr1116Conserved hypothetical protein; Acetyltransferase (GNAT) family.
spr1117 protein networkhttps://string-db.org/network/171101.spr1117Conserved hypothetical protein; Probable acetyltransferase.
uvrB protein networkhttps://string-db.org/network/171101.spr1118Exonuclease ABC - subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for ab [...]
spr1119 protein networkhttps://string-db.org/network/171101.spr1119Conserved hypothetical protein; Putative transmembrane protein.
glnP-6 protein networkhttps://string-db.org/network/171101.spr1120ABC transporter membrane spanning permease - glutamine transport.
glnQ-4 protein networkhttps://string-db.org/network/171101.spr1121ABC transporter ATP-binding protein - glutamine transport.
zwf protein networkhttps://string-db.org/network/171101.spr1122Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
ftsY protein networkhttps://string-db.org/network/171101.spr1123Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition par [...]
spr1124 protein networkhttps://string-db.org/network/171101.spr1124Conserved hypothetical protein.
spr1125 protein networkhttps://string-db.org/network/171101.spr1125Conserved hypothetical protein.
smc protein networkhttps://string-db.org/network/171101.spr1126Chromosome condensation and segregation SMC protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
rncS protein networkhttps://string-db.org/network/171101.spr1127Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some m [...]
guaC protein networkhttps://string-db.org/network/171101.spr1128GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and [...]
spr1129 protein networkhttps://string-db.org/network/171101.spr1129Hypothetical protein.
spr1130 protein networkhttps://string-db.org/network/171101.spr1130Hypothetical protein; Probable endonuclease.
spr1131 protein networkhttps://string-db.org/network/171101.spr1131Hypothetical protein.
spr1132 protein networkhttps://string-db.org/network/171101.spr1132Hypothetical protein.
spr1133 protein networkhttps://string-db.org/network/171101.spr11333-isopropylmalate dehydratase small subunit, truncation; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD [...]
spr1134 protein networkhttps://string-db.org/network/171101.spr1134Conserved hypothetical protein.
leuB protein networkhttps://string-db.org/network/171101.spr11353-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-met [...]
spr1136 protein networkhttps://string-db.org/network/171101.spr11362-isopropylmalate synthase, truncation; Belongs to the alpha-IPM synthase/homocitrate synthase family.
spr1137 protein networkhttps://string-db.org/network/171101.spr11372-isopropylmalate synthase, truncation.
spr1138 protein networkhttps://string-db.org/network/171101.spr1138Hypothetical protein.
cutC protein networkhttps://string-db.org/network/171101.spr1139Copper sensitivity; Participates in the control of copper homeostasis. Belongs to the CutC family.
spr1140 protein networkhttps://string-db.org/network/171101.spr1140Conserved hypothetical protein.
topA protein networkhttps://string-db.org/network/171101.spr1141DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of [...]
spr1142 protein networkhttps://string-db.org/network/171101.spr1142Conserved hypothetical protein.
spr1143 protein networkhttps://string-db.org/network/171101.spr1143Hypothetical protein.
smf protein networkhttps://string-db.org/network/171101.spr1144DNA processing Smf protein; Protein that helps load RecA onto ssDNA during transformation. Required for DNA transformation. Not required for DNA uptake but for a later stage of transformation. Th [...]
licC protein networkhttps://string-db.org/network/171101.spr1145Homologous to LicC, which regulates expression of LPS epitopes in H. influenzae.
licB protein networkhttps://string-db.org/network/171101.spr1146Homologous to LicB, which regulates expression of LPS epitopes in H. influenzae.
pck protein networkhttps://string-db.org/network/171101.spr1147Choline kinase.
tarJ protein networkhttps://string-db.org/network/171101.spr1148Conserved hypothetical protein; Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate.
tarI protein networkhttps://string-db.org/network/171101.spr1149Conserved hypothetical protein; Catalyzes the transfer of the cytidylyl group of CTP to D- ribitol 5-phosphate.
spr1150 protein networkhttps://string-db.org/network/171101.spr1150Conserved hypothetical protein; Probable oligosaccharide repeat unit transporter.
licD1 protein networkhttps://string-db.org/network/171101.spr1151Required for phosphorylcholine incorporation in teichoic and lipoteichoic acids.
licD2 protein networkhttps://string-db.org/network/171101.spr1152licD Protein; Required for phosphorylcholine incorporation in teichoic and lipoteichoic acids.
carB protein networkhttps://string-db.org/network/171101.spr1153Carbamoylphosphate synthase (ammonia), heavy subunit.
carA protein networkhttps://string-db.org/network/171101.spr1154Carbamoylphosphate synthase (glutamine-hydrolysing) light subunit; Belongs to the CarA family.
pyrB protein networkhttps://string-db.org/network/171101.spr1155Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
pyrR protein networkhttps://string-db.org/network/171101.spr1156Transcriptional attenuation of the pyrimidine operon / uracil phosphoribosyltransferase activity; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a u [...]
nth protein networkhttps://string-db.org/network/171101.spr1157Endonuclease III (DNA repair); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cl [...]
spr1158 protein networkhttps://string-db.org/network/171101.spr1158Conserved hypothetical protein.
spr1159 protein networkhttps://string-db.org/network/171101.spr1159Hypothetical protein.
spr1160 protein networkhttps://string-db.org/network/171101.spr1160Hypothetical protein.
ABC-NBD-18 protein networkhttps://string-db.org/network/171101.spr1161ABC transporter ATP-binding protein - unknown substrate.
htpX protein networkhttps://string-db.org/network/171101.spr1162Heat shock protein; Belongs to the peptidase M48B family.
lemA protein networkhttps://string-db.org/network/171101.spr1163Cytoplasmic membrane protein.
gidB protein networkhttps://string-db.org/network/171101.spr1164Glucose inhibited division protein B; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
pyrP protein networkhttps://string-db.org/network/171101.spr1165Uracil permease.
ffh protein networkhttps://string-db.org/network/171101.spr1166Signal recognition particle (Fifty four homolog); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the r [...]
spr1167 protein networkhttps://string-db.org/network/171101.spr1167Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory [...]
spr1168 protein networkhttps://string-db.org/network/171101.spr1168Hypothetical protein.
spr1169 protein networkhttps://string-db.org/network/171101.spr1169Conserved hypothetical protein.
spr1170 protein networkhttps://string-db.org/network/171101.spr1170Conserved hypothetical protein.
rplS protein networkhttps://string-db.org/network/171101.spr117150S Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
crcB protein networkhttps://string-db.org/network/171101.spr1172CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
crcB-2 protein networkhttps://string-db.org/network/171101.spr1173CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
spr1174 protein networkhttps://string-db.org/network/171101.spr1174Strong similarity to chorismate mutase; prephenate dehydratase.
flaV protein networkhttps://string-db.org/network/171101.spr1175Flavodoxin.
spr1176 protein networkhttps://string-db.org/network/171101.spr1176Conserved hypothetical protein.
rpmE protein networkhttps://string-db.org/network/171101.spr117750S ribosomal protein L31.
spr1178 protein networkhttps://string-db.org/network/171101.spr1178Hypothetical protein.
spr1179 protein networkhttps://string-db.org/network/171101.spr1179Conserved hypothetical protein.
spr1180 protein networkhttps://string-db.org/network/171101.spr1180Degenerate transposase.
gdhA protein networkhttps://string-db.org/network/171101.spr1181NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
spr1182 protein networkhttps://string-db.org/network/171101.spr1182Hypothetical protein.
spr1183 protein networkhttps://string-db.org/network/171101.spr1183ABC transporter ATP-bindng protein - possibly multidrug efflux, truncation.
spr1184 protein networkhttps://string-db.org/network/171101.spr1184Hypothetical protein.
spr1185 protein networkhttps://string-db.org/network/171101.spr1185Hypothetical protein.
spr1186 protein networkhttps://string-db.org/network/171101.spr1186N-acetylneuraminate lyase subunit, truncation; Belongs to the DapA family.
spr1187 protein networkhttps://string-db.org/network/171101.spr1187N-acetylneuraminate lyase subunit, truncation.
cdd-2 protein networkhttps://string-db.org/network/171101.spr1188Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
spr1189 protein networkhttps://string-db.org/network/171101.spr1189Conserved hypothetical protein.
spr1190 protein networkhttps://string-db.org/network/171101.spr1190Hypothetical protein.
appD protein networkhttps://string-db.org/network/171101.spr1191ABC transporter ATP-binding protein - oligopeptide transport; Belongs to the ABC transporter superfamily.
appC protein networkhttps://string-db.org/network/171101.spr1192ABC transporter membrane-spanning permease - oligopeptide transport.
appB protein networkhttps://string-db.org/network/171101.spr1193ABC transporter membrane-spanning permease - oligopeptide transport.
appA protein networkhttps://string-db.org/network/171101.spr1194ABC transporter substrate-binding protein - oligopeptide transport.
spr1195 protein networkhttps://string-db.org/network/171101.spr1195Conserved hypothetical protein.
nanE protein networkhttps://string-db.org/network/171101.spr1196N-acetylmannosamine-6-P epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
spr1197 protein networkhttps://string-db.org/network/171101.spr1197Degenerate transposase (orf2).
spr1198 protein networkhttps://string-db.org/network/171101.spr1198Degenerate transposase.
spr1201 protein networkhttps://string-db.org/network/171101.spr1201Hypothetical protein.
ABC-NDB protein networkhttps://string-db.org/network/171101.spr1202ABC transporter ATP-binding protein - unknown substrate.
ABC-NP-2 protein networkhttps://string-db.org/network/171101.spr1203ABC transporter ATP-binding/membrane spanning protein - multidrug resistance.
ptrB protein networkhttps://string-db.org/network/171101.spr1204Protease II (oligopeptidase B).
spr1205 protein networkhttps://string-db.org/network/171101.spr1205Conserved hypothetical protein.
spr1206 protein networkhttps://string-db.org/network/171101.spr1206Hypothetical protein.
spr1207 protein networkhttps://string-db.org/network/171101.spr1207Hypothetical protein.
spr1208 protein networkhttps://string-db.org/network/171101.spr1208Hypothetical protein.
spr1209 protein networkhttps://string-db.org/network/171101.spr1209Hypothetical protein.
spr1210 protein networkhttps://string-db.org/network/171101.spr1210Hypothetical protein.
rplL protein networkhttps://string-db.org/network/171101.spr121150S Ribosomal protein L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacte [...]
rplJ protein networkhttps://string-db.org/network/171101.spr121250S Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal prot [...]
spr1213 protein networkhttps://string-db.org/network/171101.spr1213Hypothetical protein.
trzA protein networkhttps://string-db.org/network/171101.spr1214N-ethylammeline chlorohydrolase.
ABC-N/P protein networkhttps://string-db.org/network/171101.spr1215ABC transporter ATP-binding/membrane-spanning protein - unknown substrate.
ABC-N/P-2 protein networkhttps://string-db.org/network/171101.spr1216ABC transporter ATP-binding/membrane-spanning protein - unknown substrate.
msrA-2 protein networkhttps://string-db.org/network/171101.spr1217Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation (By similarity). Catalyzes the reversible oxidation-reduc [...]
thrB protein networkhttps://string-db.org/network/171101.spr1218Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
hom protein networkhttps://string-db.org/network/171101.spr1219Homoserine dehydrogenase.
mecA protein networkhttps://string-db.org/network/171101.spr1220Negative regulator of genetic competence; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
spr1221 protein networkhttps://string-db.org/network/171101.spr1221Hypothetical protein.
spr1222 protein networkhttps://string-db.org/network/171101.spr1222Hypothetical protein.
cps23FU protein networkhttps://string-db.org/network/171101.spr1223Galactosyl transferase paralog.
spr1224 protein networkhttps://string-db.org/network/171101.spr1224Conserved hypothetical protein; Similar to capsular polysaccharide biosynthsis protein.
licD1-2 protein networkhttps://string-db.org/network/171101.spr1225LicD1 paralog.
spr1226 protein networkhttps://string-db.org/network/171101.spr1226Conserved hypothetical protein; Putative transcriptional regulator.
pheA protein networkhttps://string-db.org/network/171101.spr1227Prephenate dehydratase.
aroK protein networkhttps://string-db.org/network/171101.spr1228Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
aroA protein networkhttps://string-db.org/network/171101.spr12293-Enolpyruvylshikimate-5-phosphate synthetase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvy [...]
spr1230 protein networkhttps://string-db.org/network/171101.spr1230Conserved hypothetical protein; Belongs to the UPF0342 family.
tyrA protein networkhttps://string-db.org/network/171101.spr1231Prephenate dehydrogenase.
aroC protein networkhttps://string-db.org/network/171101.spr1232Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
aroB protein networkhttps://string-db.org/network/171101.spr12333-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquin [...]
aroE protein networkhttps://string-db.org/network/171101.spr1234Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshiki [...]
aroD protein networkhttps://string-db.org/network/171101.spr12353-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DH [...]
spr1236 protein networkhttps://string-db.org/network/171101.spr1236Conserved hypothetical protein.
spr1237 protein networkhttps://string-db.org/network/171101.spr1237Hypothetical protein.
ABC-NBD-19 protein networkhttps://string-db.org/network/171101.spr1238ABC transporter ATP-binding protein - unknown substrate.
amy protein networkhttps://string-db.org/network/171101.spr1239Alpha-amylase precursor; Belongs to the glycosyl hydrolase 13 family.
alaS protein networkhttps://string-db.org/network/171101.spr1240Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
spr1241 protein networkhttps://string-db.org/network/171101.spr1241Conserved hypothetical protein.
spr1242 protein networkhttps://string-db.org/network/171101.spr1242Hypothetical protein.
potD protein networkhttps://string-db.org/network/171101.spr1243ABC transporter substrate-binding protein - spermidine/putrescine transport.
potC protein networkhttps://string-db.org/network/171101.spr1244ABC transporter membrane-spanning permease - spermidine/putrescine transport.
potB protein networkhttps://string-db.org/network/171101.spr1245ABC transporter membrane-spanning permease - spermidine/putrescine transport.
potA protein networkhttps://string-db.org/network/171101.spr1246ABC transporter ATP-binding protein - spermidine/putrescine transport; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the [...]
murB protein networkhttps://string-db.org/network/171101.spr1247UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
spr1248 protein networkhttps://string-db.org/network/171101.spr1248Conserved hypothetical protein.
aldB protein networkhttps://string-db.org/network/171101.spr1249Alpha-acetolactate decarboxylase.
spr1250 protein networkhttps://string-db.org/network/171101.spr1250Conserved hypothetical protein.
glnH-3 protein networkhttps://string-db.org/network/171101.spr1251ABC transporter substrate-binding protein - glutamine-binding protein.
phoU protein networkhttps://string-db.org/network/171101.spr1252Phosphate transport system regulatory protein; Plays a role in the regulation of phosphate uptake.
pstB protein networkhttps://string-db.org/network/171101.spr1253ABC transporter ATP-binding protein - phosphate transport; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belon [...]
pstB-2 protein networkhttps://string-db.org/network/171101.spr1254ABC transporter ATP-binding protein - phosphate transport; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belon [...]
pstA protein networkhttps://string-db.org/network/171101.spr1255ABC transporter membrane-spanning permease - phosphate transport.
pstC protein networkhttps://string-db.org/network/171101.spr1256ABC transporter membrane-spanning permease - phosphate transport; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate [...]
pstS protein networkhttps://string-db.org/network/171101.spr1257ABC transporter substrate-binding protein - phosphate transport; Part of the ABC transporter complex PstSACB involved in phosphate import.
spr1258 protein networkhttps://string-db.org/network/171101.spr1258Hypothetical protein.
spr1259 protein networkhttps://string-db.org/network/171101.spr1259Conserved hypothetical protein.
spr1260 protein networkhttps://string-db.org/network/171101.spr1260Conserved hypothetical protein; Similar to E. coli extragenic suppressor protein SuhB.
spr1261 protein networkhttps://string-db.org/network/171101.spr1261Conserved hypothetical protein; Belongs to the UPF0223 family.
spxA protein networkhttps://string-db.org/network/171101.spr1262Conserved hypothetical protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involve [...]
spr1263 protein networkhttps://string-db.org/network/171101.spr1263Hypothetical protein.
nagD protein networkhttps://string-db.org/network/171101.spr1264N-acetyl-glucosamine matabolism.
spr1265 protein networkhttps://string-db.org/network/171101.spr1265Hypothetical protein; Acyl-ACP thioesterase family.
hemN protein networkhttps://string-db.org/network/171101.spr1266Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. [...]
spr1267 protein networkhttps://string-db.org/network/171101.spr1267Conserved hypothetical protein.
spr1268 protein networkhttps://string-db.org/network/171101.spr1268Conserved hypothetical protein.
lgt protein networkhttps://string-db.org/network/171101.spr1269Prolipoprotein diacylglycerol transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
hprK protein networkhttps://string-db.org/network/171101.spr1270HPr(ser-P)kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-de [...]
rpsU protein networkhttps://string-db.org/network/171101.spr127130S Ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
nagB protein networkhttps://string-db.org/network/171101.spr1272N-acetylglucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
queA protein networkhttps://string-db.org/network/171101.spr1273S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ [...]
spr1274 protein networkhttps://string-db.org/network/171101.spr1274Choline binding protein.
spr1275 protein networkhttps://string-db.org/network/171101.spr1275Conserved hypothetical protein; Putative alanine acetyl transferase.
nadE protein networkhttps://string-db.org/network/171101.spr1276NAD synthetase, ammonia dependent; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
spr1277 protein networkhttps://string-db.org/network/171101.spr1277Conserved hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-pho [...]
spr1278 protein networkhttps://string-db.org/network/171101.spr1278Hypothetical protein.
spr1279 protein networkhttps://string-db.org/network/171101.spr1279Conserved hypothetical protein; Putative transcription regulator.
spr1280 protein networkhttps://string-db.org/network/171101.spr1280Hypothetical protein.
ABC-NBD-20 protein networkhttps://string-db.org/network/171101.spr1281ABC transporter ATP-binding protein - multidrug efflux.
spr1282 protein networkhttps://string-db.org/network/171101.spr1282Hypothetical protein.
spr1283 protein networkhttps://string-db.org/network/171101.spr1283Hypothetical protein.
spr1284 protein networkhttps://string-db.org/network/171101.spr1284Protease.
spr1285 protein networkhttps://string-db.org/network/171101.spr1285Type II restriction endonuclease, uncharacterized, truncation.
spr1286 protein networkhttps://string-db.org/network/171101.spr1286Type II restriction endonuclease, uncharacterized, truncation.
spnIM protein networkhttps://string-db.org/network/171101.spr1287DNA modification methyltransferase; Belongs to the N(4)/N(6)-methyltransferase family.
spr1288 protein networkhttps://string-db.org/network/171101.spr1288Hypothetical protein.
ABC-N/P-3 protein networkhttps://string-db.org/network/171101.spr1289ABC transporter ATP-binding/membrane-spanning protein - unknown substrate.
ABC-N/P-4 protein networkhttps://string-db.org/network/171101.spr1290ABC transporter ATP-binding/membrane-spanning protein - unknown substrate.
spr1291 protein networkhttps://string-db.org/network/171101.spr1291Hypothetical protein.
spr1292 protein networkhttps://string-db.org/network/171101.spr1292Conserved hypothetical protein.
ABC-NBD-21 protein networkhttps://string-db.org/network/171101.spr1293ABC transporter ATP-binding protein - unknown substrate.
spr1294 protein networkhttps://string-db.org/network/171101.spr1294Hypothetical protein.
spr1295 protein networkhttps://string-db.org/network/171101.spr1295Transposase, uncharacterized, truncation.
spr1296 protein networkhttps://string-db.org/network/171101.spr1296Hypothetical protein.
spr1297 protein networkhttps://string-db.org/network/171101.spr1297Hypothetical protein.
Transposase_E protein networkhttps://string-db.org/network/171101.spr1298Degenerate transposase.
spr1299 protein networkhttps://string-db.org/network/171101.spr1299Degenerate transposase (orf1).
guaA protein networkhttps://string-db.org/network/171101.spr1300Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP.
spr1301 protein networkhttps://string-db.org/network/171101.spr1301Conserved hypothetical protein; Probable transcription regulator, GntR family.
spr1302 protein networkhttps://string-db.org/network/171101.spr1302Conserved hypothetical protein; Putative membrane protein.
spr1303 protein networkhttps://string-db.org/network/171101.spr1303Hypothetical protein.
cppA protein networkhttps://string-db.org/network/171101.spr1304C3-degrading proteinase.
spr1305 protein networkhttps://string-db.org/network/171101.spr1305Hypothetical protein.
spr1306 protein networkhttps://string-db.org/network/171101.spr1306Conserved hypothetical protein.
spr1307 protein networkhttps://string-db.org/network/171101.spr1307Hypothetical protein.
spr1308 protein networkhttps://string-db.org/network/171101.spr1308Hypothetical protein.
spr1309 protein networkhttps://string-db.org/network/171101.spr1309Hypothetical protein.
fms protein networkhttps://string-db.org/network/171101.spr1310Peptide deformylase, N-formylmethionylaminoacyl-tRNA deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient ra [...]
trmH protein networkhttps://string-db.org/network/171101.spr1311tRNA (guanosine-2'-O-)-methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
trxB protein networkhttps://string-db.org/network/171101.spr1312Thioredoxin reductase.
spr1313 protein networkhttps://string-db.org/network/171101.spr1313Hypothetical protein.
ABC-NDB-2 protein networkhttps://string-db.org/network/171101.spr1314ABC transporter ATP-binding protein - aspartate/glutamate transport.
ABC-MSP-13 protein networkhttps://string-db.org/network/171101.spr1315ABC transporter membrane-spanning permease - aspartate/glutamate transport.
spr1316 protein networkhttps://string-db.org/network/171101.spr1316Conserved hypothetical protein; Similar to arsenate reductase; Belongs to the ArsC family.
ogt protein networkhttps://string-db.org/network/171101.spr1317O6-methylguanine-DNA methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated n [...]
spr1318 protein networkhttps://string-db.org/network/171101.spr1318Hypothetical protein; Putative acetyltransferase.
spr1319 protein networkhttps://string-db.org/network/171101.spr1319Hypothetical protein.
spr1320 protein networkhttps://string-db.org/network/171101.spr1320Conserved hypothetical protein; Similar to hemolysin III.
pdxT protein networkhttps://string-db.org/network/171101.spr1321Conserved hypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled t [...]
pdx1 protein networkhttps://string-db.org/network/171101.spr1322Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT [...]
nox protein networkhttps://string-db.org/network/171101.spr1323NADH oxidase.
apbE protein networkhttps://string-db.org/network/171101.spr1324Thiamine biosynthesis lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavop [...]
spr1325 protein networkhttps://string-db.org/network/171101.spr1325Conserved hypothetical protein.
spr1326 protein networkhttps://string-db.org/network/171101.spr1326Hypothetical protein.
spr1327 protein networkhttps://string-db.org/network/171101.spr1327Conserved hypothetical protein.
glyS protein networkhttps://string-db.org/network/171101.spr1328Glycyl-tRNA synthetase beta chain.
glyQ protein networkhttps://string-db.org/network/171101.spr1329Glycyl-tRNA synthetase alpha chain.
spr1330 protein networkhttps://string-db.org/network/171101.spr1330Hypothetical protein.
spr1331 protein networkhttps://string-db.org/network/171101.spr1331Hypothetical protein.
spr1332 protein networkhttps://string-db.org/network/171101.spr1332Conserved hypothetical protein; Putative oxidoreductase.
pgdA protein networkhttps://string-db.org/network/171101.spr1333Peptidoglycan GlcNAc deacetylase; Catalyzes the deacetylation of N-acetylglucosamine (GlcNAc) residues in peptidoglycan, a modification that confers host lysozyme resistance and contributes to pn [...]
spr1334 protein networkhttps://string-db.org/network/171101.spr1334Hypothetical protein.
mocA protein networkhttps://string-db.org/network/171101.spr1335Oxidoreductase.
DEAD/H protein networkhttps://string-db.org/network/171101.spr1336DEAD RNA helicase.
spr1337 protein networkhttps://string-db.org/network/171101.spr1337Degenerate transposase.
spr1338 protein networkhttps://string-db.org/network/171101.spr1338Degenerate transposase.
spr1339 protein networkhttps://string-db.org/network/171101.spr1339Degenerate transposase (orf2).
spr1340 protein networkhttps://string-db.org/network/171101.spr1340Degenerate transposase (orf2).
spr1341 protein networkhttps://string-db.org/network/171101.spr1341Degenerate transposase (orf1).
spr1342 protein networkhttps://string-db.org/network/171101.spr1342Degenerate transposase.
tufA protein networkhttps://string-db.org/network/171101.spr1343Translation elongation factor TU; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
glpF protein networkhttps://string-db.org/network/171101.spr1344Glycerol uptake facilitator protein paralog; Belongs to the MIP/aquaporin (TC 1.A.8) family.
spr1345 protein networkhttps://string-db.org/network/171101.spr1345Hypothetical protein.
spr1346 protein networkhttps://string-db.org/network/171101.spr1346Hypothetical protein.
spr1347 protein networkhttps://string-db.org/network/171101.spr1347Hypothetical protein.
spr1348 protein networkhttps://string-db.org/network/171101.spr1348Hypothetical protein.
spr1349 protein networkhttps://string-db.org/network/171101.spr1349Degenerate transposase.
spr1350 protein networkhttps://string-db.org/network/171101.spr1350Degenerative transposase.
pgm protein networkhttps://string-db.org/network/171101.spr1351Phosphoglucomutase.
bta protein networkhttps://string-db.org/network/171101.spr1352Bacterocin transport accessory protein.
glnH-4 protein networkhttps://string-db.org/network/171101.spr1353ABC transporter substrate-binding protein - glutamine transport.
glnQ-5 protein networkhttps://string-db.org/network/171101.spr1354ABC transporter ATP-binding protein - glutamine transport.
glnP-7 protein networkhttps://string-db.org/network/171101.spr1355ABC transporter membrane-spanning permease - glutamine transport.
spr1356 protein networkhttps://string-db.org/network/171101.spr1356Conserved hypothetical protein.
spr1357 protein networkhttps://string-db.org/network/171101.spr1357Conserved hypothetical protein; Putative membrane protein.
spr1358 protein networkhttps://string-db.org/network/171101.spr1358Conserved hypothetical protein.
atpC protein networkhttps://string-db.org/network/171101.spr1359Proton-translocating ATPase, F1 sector, epsilon-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane; Belongs to the ATPase epsilon chain family.
atpD protein networkhttps://string-db.org/network/171101.spr1360Proton-translocating ATPase, F1 sector, beta-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [...]
atpG protein networkhttps://string-db.org/network/171101.spr1361Proton-translocating ATPase, F1 sector, gamma-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating AT [...]
atpA protein networkhttps://string-db.org/network/171101.spr1362Proton-translocating ATPase, F1 sector, alpha-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
atpH protein networkhttps://string-db.org/network/171101.spr1363Proton-translocating ATPase, F1 sector, delta-subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains [...]
atpF protein networkhttps://string-db.org/network/171101.spr1364Proton-translocating ATPase, F0 sector, subunit b; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F( [...]
atpB protein networkhttps://string-db.org/network/171101.spr1365Proton-translocating ATPase, F0 sector, subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain f [...]
atpE protein networkhttps://string-db.org/network/171101.spr1366Proton-translocating ATPase, F0 sector, subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F( [...]
IS1239 protein networkhttps://string-db.org/network/171101.spr1367Transposase.
spr1368 protein networkhttps://string-db.org/network/171101.spr1368Hypothetical protein.
greA protein networkhttps://string-db.org/network/171101.spr1369Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...]
mltG protein networkhttps://string-db.org/network/171101.spr1370Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
spr1371 protein networkhttps://string-db.org/network/171101.spr1371Conserved hypothetical protein; Putative acetyltransferase.
spr1372 protein networkhttps://string-db.org/network/171101.spr1372Hypothetical protein; N-terminal acetyltransferase related protein.
murC protein networkhttps://string-db.org/network/171101.spr1373UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
spr1374 protein networkhttps://string-db.org/network/171101.spr1374Hypothetical protein.
snf protein networkhttps://string-db.org/network/171101.spr1375SWF/SNF family ATP-dependent RNA helicase.
patB protein networkhttps://string-db.org/network/171101.spr1376Aminotransferase.
metB protein networkhttps://string-db.org/network/171101.spr1377Cystathionine gamma-synthase.
spr1378 protein networkhttps://string-db.org/network/171101.spr1378ABC transporter, truncation.
spr1379 protein networkhttps://string-db.org/network/171101.spr1379ABC transporter, truncation.
spr1380 protein networkhttps://string-db.org/network/171101.spr1380ABC transporter, truncation.
spr1381 protein networkhttps://string-db.org/network/171101.spr1381ABC transporter, truncation.
aliB protein networkhttps://string-db.org/network/171101.spr1382ABC transporter substrate-binding protein - oligopeptide transport; Part of the binding-protein-dependent transport system for oligopeptides; probably an oligopeptide binding protein; Belongs to [...]
spr1383 protein networkhttps://string-db.org/network/171101.spr1383Polysaccharide transporter.
murE protein networkhttps://string-db.org/network/171101.spr1384UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L- lysine Ligase; Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of b [...]
spr1385 protein networkhttps://string-db.org/network/171101.spr1385Hypothetical protein; Belongs to the UPF0337 (CsbD) family.
spr1386 protein networkhttps://string-db.org/network/171101.spr1386Hypothetical protein.
spr1387 protein networkhttps://string-db.org/network/171101.spr1387Hypothetical protein.
spr1388 protein networkhttps://string-db.org/network/171101.spr1388Hypothetical protein.
ppaC protein networkhttps://string-db.org/network/171101.spr1389Manganese-dependent inorganic pyrophosphatase; Belongs to the PPase class C family.
spr1390 protein networkhttps://string-db.org/network/171101.spr1390Conserved hypothetical protein; Belongs to the UPF0213 family.
spr1391 protein networkhttps://string-db.org/network/171101.spr1391Conserved hypothetical protein; Belongs to the methyltransferase superfamily.
spr1392 protein networkhttps://string-db.org/network/171101.spr1392Conserved hypothetical protein; Similar to general stress protein GSP13 from Lactococcus lactis subsp. lactis and Bacillus subtilis.
spr1393 protein networkhttps://string-db.org/network/171101.spr1393Hypothetical protein.
rpsR protein networkhttps://string-db.org/network/171101.spr139430S Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosom [...]
ssbA protein networkhttps://string-db.org/network/171101.spr1395Single stranded binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action [...]
rpsF protein networkhttps://string-db.org/network/171101.spr139630S Ribosomal protein S6 (S6); Binds together with S18 to 16S ribosomal RNA.
asnS protein networkhttps://string-db.org/network/171101.spr1397Asparaginyl-tRNA synthetase (asparagine--tRNA ligase).
spr1398 protein networkhttps://string-db.org/network/171101.spr1398Conserved hypothetical protein.
aspB protein networkhttps://string-db.org/network/171101.spr1399Aspartate aminotransferase.
spr1400 protein networkhttps://string-db.org/network/171101.spr1400Conserved hypothetical protein.
spr1401 protein networkhttps://string-db.org/network/171101.spr1401Hypothetical protein.
spr1402 protein networkhttps://string-db.org/network/171101.spr1402Hypothetical protein.
spr1403 protein networkhttps://string-db.org/network/171101.spr1403Hypothetical protein.
spr1404 protein networkhttps://string-db.org/network/171101.spr1404Conserved hypothetical protein; Putative Mga-like regulatory protein.
spr1405 protein networkhttps://string-db.org/network/171101.spr1405Conserved hypothetical protein; Belongs to the UPF0246 family.
spr1406 protein networkhttps://string-db.org/network/171101.spr1406Hypothetical protein.
spr1407 protein networkhttps://string-db.org/network/171101.spr1407Hypothetical protein.
def protein networkhttps://string-db.org/network/171101.spr1408Formylmethionine deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family.
spr1409 protein networkhttps://string-db.org/network/171101.spr1409Conserved hypothetical protein; Low similarity to glutathione S-transferase.
pacL protein networkhttps://string-db.org/network/171101.spr1410P-type ATPase - calcium transporter; Putative calcium transporter.
spr1411 protein networkhttps://string-db.org/network/171101.spr1411Conserved hypothetical protein; Probable cation transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
ABC-NBD-22 protein networkhttps://string-db.org/network/171101.spr1412ABC transporter ATP-binding protein - unknown substrate.
cca protein networkhttps://string-db.org/network/171101.spr1413tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order [...]
dapB protein networkhttps://string-db.org/network/171101.spr1414Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
spr1415 protein networkhttps://string-db.org/network/171101.spr1415Conserved hypothetical protein; May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
spr1416 protein networkhttps://string-db.org/network/171101.spr1416Hypothetical protein.
glmM protein networkhttps://string-db.org/network/171101.spr1417Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
spr1418 protein networkhttps://string-db.org/network/171101.spr1418Conserved hypothetical protein.
dacA-2 protein networkhttps://string-db.org/network/171101.spr1419Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
spr1420 protein networkhttps://string-db.org/network/171101.spr1420Hypothetical protein.
trxB-2 protein networkhttps://string-db.org/network/171101.spr1421Thioredoxin reductase.
whiA protein networkhttps://string-db.org/network/171101.spr1422Conserved hypothetical protein; Involved in cell division and chromosome segregation.
spr1423 protein networkhttps://string-db.org/network/171101.spr1423Conserved hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
spr1424 protein networkhttps://string-db.org/network/171101.spr1424Conserved hypothetical protein; Displays ATPase and GTPase activities.
aldR protein networkhttps://string-db.org/network/171101.spr1425Transcription regulator.
engB protein networkhttps://string-db.org/network/171101.spr1426Conserved hypothetical protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB [...]
clpX protein networkhttps://string-db.org/network/171101.spr1427ATP-dependent Clp protease ATP-binding subunit (class III heat-shock protein); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform [...]
spr1428 protein networkhttps://string-db.org/network/171101.spr1428Hypothetical protein.
dfr protein networkhttps://string-db.org/network/171101.spr1429Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
dpr protein networkhttps://string-db.org/network/171101.spr1430DNA binding protein starved cells-like peroxide resistance protein; Belongs to the Dps family.
lytC protein networkhttps://string-db.org/network/171101.spr14311,4-beta-N-acetylmuramidase.
tpi protein networkhttps://string-db.org/network/171101.spr1432Triose phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to th [...]
spr1433 protein networkhttps://string-db.org/network/171101.spr1433Conserved hypothetical protein.
metA protein networkhttps://string-db.org/network/171101.spr1434Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
apt protein networkhttps://string-db.org/network/171101.spr1435Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
spr1436 protein networkhttps://string-db.org/network/171101.spr1436Conserved hypothetical protein; Methyltransferase-like protein.
msmK protein networkhttps://string-db.org/network/171101.spr1437ABC transporter ATP-binding protein - multiple sugar transport; Belongs to the ABC transporter superfamily.
entB protein networkhttps://string-db.org/network/171101.spr1438Isochorismatase.
codY protein networkhttps://string-db.org/network/171101.spr1439Transcriptional pleiotropic repressor; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary ph [...]
cshA-2 protein networkhttps://string-db.org/network/171101.spr1440Conserved hypothetical protein; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box [...]
oxlT protein networkhttps://string-db.org/network/171101.spr1441Major facilitator:Oxalate:Formate Antiporter.
merA protein networkhttps://string-db.org/network/171101.spr1442Oxidoreductase (Mercury (II) reductase).
murT protein networkhttps://string-db.org/network/171101.spr1443Conserved hypothetical protein; The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the [...]
cobQ protein networkhttps://string-db.org/network/171101.spr1444Cobyric acid synthase; The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysi [...]
pepQ protein networkhttps://string-db.org/network/171101.spr1445Dipeptidase; Belongs to the peptidase M24B family.
spr1446 protein networkhttps://string-db.org/network/171101.spr1446Degenerate transposase (orf2).
spr1447 protein networkhttps://string-db.org/network/171101.spr1447Degenerate transposase (orf2).
spr1448 protein networkhttps://string-db.org/network/171101.spr1448Degenerate transposase (orf1).
spr1449 protein networkhttps://string-db.org/network/171101.spr1449Conserved hypothetical protein.
pdxK protein networkhttps://string-db.org/network/171101.spr1450Pyridoxine kinase.
truA protein networkhttps://string-db.org/network/171101.spr1451tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
spr1452 protein networkhttps://string-db.org/network/171101.spr1452Hypothetical protein.
spr1453 protein networkhttps://string-db.org/network/171101.spr1453Major facilitator superfamily transporter - efflux.
spr1454 protein networkhttps://string-db.org/network/171101.spr1454Hypothetical protein.
phnA protein networkhttps://string-db.org/network/171101.spr1455Required for expression of the phosphonate utilization phenotype in E. coli.
cmk protein networkhttps://string-db.org/network/171101.spr1456Cytidylate kinase.
spr1457 protein networkhttps://string-db.org/network/171101.spr1457Hypothetical protein.
fer protein networkhttps://string-db.org/network/171101.spr1458Ferredoxin.
gtrB protein networkhttps://string-db.org/network/171101.spr1459Glycosil transferase.
galE protein networkhttps://string-db.org/network/171101.spr1460UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
spr1461 protein networkhttps://string-db.org/network/171101.spr1461Conserved hypothetical protein; Probable oxidase.
spr1462 protein networkhttps://string-db.org/network/171101.spr1462Conserved hypothetical protein.
spr1463 protein networkhttps://string-db.org/network/171101.spr1463Conserved hypothetical protein.
ctpE protein networkhttps://string-db.org/network/171101.spr1464P-type ATPase - metal cation transport.
plsC protein networkhttps://string-db.org/network/171101.spr1465Conserved hypothetical protein; Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl don [...]
cadD protein networkhttps://string-db.org/network/171101.spr1466Confers low level cadmium resistance in Staphylococcus aureus.
rpsO protein networkhttps://string-db.org/network/171101.spr146730S Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging seve [...]
spr1468 protein networkhttps://string-db.org/network/171101.spr1468Conserved hypothetical protein.
spr1469 protein networkhttps://string-db.org/network/171101.spr1469Hypothetical protein.
spr1470 protein networkhttps://string-db.org/network/171101.spr1470Hypothetical protein.
spr1471 protein networkhttps://string-db.org/network/171101.spr1471Hypothetical protein.
thrS protein networkhttps://string-db.org/network/171101.spr1472Threonyl-tRNA synthetase 1; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor [...]
hk01 protein networkhttps://string-db.org/network/171101.spr1473Histidine kinase.
rr01 protein networkhttps://string-db.org/network/171101.spr1474Response regulator.
spr1475 protein networkhttps://string-db.org/network/171101.spr1475Hypothetical protein.
spr1476 protein networkhttps://string-db.org/network/171101.spr1476Hypothetical protein.
spr1477 protein networkhttps://string-db.org/network/171101.spr1477Conserved hypothetical protein.
spr1479 protein networkhttps://string-db.org/network/171101.spr1479Conserved hypothetical protein.
marR protein networkhttps://string-db.org/network/171101.spr1480Metalloregulator.
spr1481 protein networkhttps://string-db.org/network/171101.spr1481Hypothetical protein.
spr1482 protein networkhttps://string-db.org/network/171101.spr1482Hypothetical protein.
spr1483 protein networkhttps://string-db.org/network/171101.spr1483Hypothetical protein.
spr1484 protein networkhttps://string-db.org/network/171101.spr1484Hypothetical protein.
dtd protein networkhttps://string-db.org/network/171101.spr1486Conserved hypothetical protein; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischa [...]
relA protein networkhttps://string-db.org/network/171101.spr1487GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to chan [...]
spr1488 protein networkhttps://string-db.org/network/171101.spr1488Hypothetical protein.
spr1489 protein networkhttps://string-db.org/network/171101.spr1489Hypothetical protein.
spr1490 protein networkhttps://string-db.org/network/171101.spr1490Conserved hypothetical protein; Probable member of metallo-beta-lactamase superfamily.
pepO protein networkhttps://string-db.org/network/171101.spr1491Endopeptidase O.
psaB protein networkhttps://string-db.org/network/171101.spr1492ABC transporter ATP-binding protein - manganese transport.
psaC protein networkhttps://string-db.org/network/171101.spr1493ABC transporter membrane-spanning permease - manganese transport.
psaA protein networkhttps://string-db.org/network/171101.spr1494ABC transporter substrate-binding protein - manganese transport; Part of an ATP-driven transport system; Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lr [...]
tpx protein networkhttps://string-db.org/network/171101.spr1495Thioredoxin-linked thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in ce [...]
spr1496 protein networkhttps://string-db.org/network/171101.spr1496Hypothetical protein.
ABC-NBD-23 protein networkhttps://string-db.org/network/171101.spr1497ABC transporter ATP-binding protein - unknown substrate.
spr1498 protein networkhttps://string-db.org/network/171101.spr1498Conserved hypothetical protein; Putative large secreted protein.
gpmA protein networkhttps://string-db.org/network/171101.spr1499Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
spr1500 protein networkhttps://string-db.org/network/171101.spr1500Hypothetical protein.
ileS protein networkhttps://string-db.org/network/171101.spr1502Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
spr1503 protein networkhttps://string-db.org/network/171101.spr1503Hypothetical protein.
spr1504 protein networkhttps://string-db.org/network/171101.spr1504Hypothetical protein.
divIVA protein networkhttps://string-db.org/network/171101.spr1505Cell-division initiation protein (septum placement); Appears to have a multifaceted role in controlling cell morphology, completion of cell division and separation, as well as chromosome segregat [...]
spr1506 protein networkhttps://string-db.org/network/171101.spr1506Conserved hypothetical protein.
spr1507 protein networkhttps://string-db.org/network/171101.spr1507Conserved hypothetical protein.
sepF protein networkhttps://string-db.org/network/171101.spr1508Conserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-li [...]
spr1509 protein networkhttps://string-db.org/network/171101.spr1509Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
ftsZ protein networkhttps://string-db.org/network/171101.spr1510Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...]
ftsA protein networkhttps://string-db.org/network/171101.spr1511Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
spr1512 protein networkhttps://string-db.org/network/171101.spr1512Hypothetical protein.
mutT protein networkhttps://string-db.org/network/171101.spr1513Mutator protein.
murF protein networkhttps://string-db.org/network/171101.spr1514UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D- alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the prec [...]
ddl protein networkhttps://string-db.org/network/171101.spr1515D-alanine-D-alanine ligase; Cell wall formation.
recR protein networkhttps://string-db.org/network/171101.spr1516Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity). Pl [...]
pbp2b protein networkhttps://string-db.org/network/171101.spr1517Penicillin-binding protein 2B.
spr1518 protein networkhttps://string-db.org/network/171101.spr1518Conserved hypothetical protein; Probable transcriptional regulator.
glk protein networkhttps://string-db.org/network/171101.spr1519Glucokinase.
spr1520 protein networkhttps://string-db.org/network/171101.spr1520N-acetylneuraminate lyase subunit, truncation; Belongs to the DapA family.
spr1521 protein networkhttps://string-db.org/network/171101.spr1521N-acetylneuraminate lyase subunit, truncation.
spr1522 protein networkhttps://string-db.org/network/171101.spr1522Hypothetical protein.
spr1523 protein networkhttps://string-db.org/network/171101.spr1523Hypothetical protein.
spr1524 protein networkhttps://string-db.org/network/171101.spr1524Conserved hypothetical protein.
ABC-MSP-14 protein networkhttps://string-db.org/network/171101.spr1525ABC transporter membrane-spanning permease - sugar transport.
ABC-MSP-15 protein networkhttps://string-db.org/network/171101.spr1526ABC transporter membrane-spanning permease - sugar transport.
ABC-SBP-8 protein networkhttps://string-db.org/network/171101.spr1527ABC transporter substrate-binding protein - sugar transport.
PTS-EII-15 protein networkhttps://string-db.org/network/171101.spr1528Phosphotransferase system sugar-specific EII component.
nanE-2 protein networkhttps://string-db.org/network/171101.spr1529N-acetylmannosamine-6-P epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
spr1530 protein networkhttps://string-db.org/network/171101.spr1530Conserved hypothetical protein; Probable Oxidoreductase, GFO/IDH/MOCA family.
nanB protein networkhttps://string-db.org/network/171101.spr1531Sialidase B precursor (neuraminidase B).
ABC-MSP-16 protein networkhttps://string-db.org/network/171101.spr1532ABC transporter membrane-spanning permease - sugar transport.
ABC-MSP-17 protein networkhttps://string-db.org/network/171101.spr1533ABC transporter membrane-spanning permease - sugar transport.
ABC-SBP-9 protein networkhttps://string-db.org/network/171101.spr1534ABC transporter substrate-binding protein - sugar transport.
spr1535 protein networkhttps://string-db.org/network/171101.spr1535Hypothetical protein.
nanA protein networkhttps://string-db.org/network/171101.spr1536Sialidase A precursor (neuraminidase A); Belongs to the glycosyl hydrolase 33 family.
spr1537 protein networkhttps://string-db.org/network/171101.spr1537Hypothetical protein.
axe1 protein networkhttps://string-db.org/network/171101.spr1538Xylan esterase 1.
recG protein networkhttps://string-db.org/network/171101.spr1539Branch migration of Holliday junctions, junction-specific DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzi [...]
alr protein networkhttps://string-db.org/network/171101.spr1540Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
acpS protein networkhttps://string-db.org/network/171101.spr1541Acyl Carrier protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
aroF protein networkhttps://string-db.org/network/171101.spr1542Phospho-2-dehydro-3-deoxyheptonate aldolase (DAHP synthatase); Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulo [...]
aroG protein networkhttps://string-db.org/network/171101.spr1543Phospho-2-dehydro-3-deoxyheptonate aldolase (DAHP synthatase isozyme)- possibly phe sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving ri [...]
secA protein networkhttps://string-db.org/network/171101.spr1544Preprotein translocase secA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to [...]
spr1545 protein networkhttps://string-db.org/network/171101.spr1545Hypothetical protein.
ABC-NBD-24 protein networkhttps://string-db.org/network/171101.spr1546ABC transporter ATP-binding protein - unknown substrate.
spr1547 protein networkhttps://string-db.org/network/171101.spr1547Hypothetical protein.
spr1548 protein networkhttps://string-db.org/network/171101.spr1548Hypothetical protein.
spr1549 protein networkhttps://string-db.org/network/171101.spr1549Hypothetical protein.
spr1550 protein networkhttps://string-db.org/network/171101.spr1550Conserved hypothetical protein; Similar to MutR protein.
spr1551 protein networkhttps://string-db.org/network/171101.spr1551Hypothetical protein.
spr1552 protein networkhttps://string-db.org/network/171101.spr1552Hypothetical protein.
serA protein networkhttps://string-db.org/network/171101.spr1553Phosphoglycerate dehydrogenase; GTPase that plays an essential role in the late steps of ribosome biogenesis.
frp protein networkhttps://string-db.org/network/171101.spr1554Homologue of NADPH-flavin oxidoreductase; Belongs to the flavin oxidoreductase frp family.
dnaI protein networkhttps://string-db.org/network/171101.spr1555Primosome component (helicase loader).
dnaB protein networkhttps://string-db.org/network/171101.spr1556Chromosome replication initiation protein/membrane attachment protein, Putative.
nrdR protein networkhttps://string-db.org/network/171101.spr1557Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
spr1558 protein networkhttps://string-db.org/network/171101.spr1558Conserved hypothetical protein; Similar to transcriptional regulator (GntR family).
ABC-NBD-25 protein networkhttps://string-db.org/network/171101.spr1559ABC transporter ATP-binding protein - unknown substrate.
spr1560 protein networkhttps://string-db.org/network/171101.spr1560Hypothetical protein.
natB protein networkhttps://string-db.org/network/171101.spr1561ABC transporter membrane-spanning permease - Na+ export.
natA protein networkhttps://string-db.org/network/171101.spr1562ABC transporter ATP-binding protein - Na+ export.
spr1563 protein networkhttps://string-db.org/network/171101.spr1563Degenerate transposase.
spr1564 protein networkhttps://string-db.org/network/171101.spr1564Hypothetical protein.
scrK protein networkhttps://string-db.org/network/171101.spr1565Fructokinase.
scrA protein networkhttps://string-db.org/network/171101.spr1566Phosphotransferase system enzyme II.
scrB protein networkhttps://string-db.org/network/171101.spr1568Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
scrR protein networkhttps://string-db.org/network/171101.spr1569Sucrose regulon regulatory protein.
mvaA protein networkhttps://string-db.org/network/171101.spr15703-hydroxy-3-methylglutaryl-coenzyme a reductase; Belongs to the HMG-CoA reductase family.
mvaS protein networkhttps://string-db.org/network/171101.spr15713-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase.
spr1572 protein networkhttps://string-db.org/network/171101.spr1572Hypothetical protein.
IS1381-4 protein networkhttps://string-db.org/network/171101.spr1573Tranposase (orf2).
spr1574 protein networkhttps://string-db.org/network/171101.spr1574Degenerate transposase (orf1).
spr1575 protein networkhttps://string-db.org/network/171101.spr1575Hypothetical protein.
spr1576 protein networkhttps://string-db.org/network/171101.spr1576Conserved hypothetical protein.
pkn2 protein networkhttps://string-db.org/network/171101.spr1577Eukaryotic-type serine/threonine kinase; Protein kinase involved in signal transduction pathways that regulate various cellular processes. Likely senses intracellular peptidoglycan subunits prese [...]
pppL protein networkhttps://string-db.org/network/171101.spr1578Phosphoprotein phosphatase; Protein phosphatase able to dephosphorylate StkP-P and other phosphorylated protein substrates. PhpP and its cognate protein kinase StkP appear to constitute a functio [...]
sunL protein networkhttps://string-db.org/network/171101.spr1579rRNA methylase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
fmt protein networkhttps://string-db.org/network/171101.spr1580Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
priA protein networkhttps://string-db.org/network/171101.spr1581Primosomal replication factor Y; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex [...]
rpoZ protein networkhttps://string-db.org/network/171101.spr1582Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
gmk protein networkhttps://string-db.org/network/171101.spr1583Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
rny protein networkhttps://string-db.org/network/171101.spr1584Conserved hypothetical protein; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
spr1585 protein networkhttps://string-db.org/network/171101.spr1585Conserved hypothetical protein.
spr1586 protein networkhttps://string-db.org/network/171101.spr1586Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
tmcAL protein networkhttps://string-db.org/network/171101.spr1587Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acet [...]
spr1588 protein networkhttps://string-db.org/network/171101.spr1588Conserved hypothetical protein.
rsfS protein networkhttps://string-db.org/network/171101.spr1589Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 3 [...]
spr1590 protein networkhttps://string-db.org/network/171101.spr1590Conserved hypothetical protein; Similar to isochorismatase.
spr1591 protein networkhttps://string-db.org/network/171101.spr1591Conserved hypothetical protein.
nadD protein networkhttps://string-db.org/network/171101.spr1592Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
spr1593 protein networkhttps://string-db.org/network/171101.spr1593Conserved hypothetical protein.
spr1594 protein networkhttps://string-db.org/network/171101.spr1594Conserved hypothetical protein; Similar to GTP-binding protein.
spr1595 protein networkhttps://string-db.org/network/171101.spr1595Conserved hypothetical protein.
corA-2 protein networkhttps://string-db.org/network/171101.spr1596CorA - magnesium and cobalt transporter.
spr1597 protein networkhttps://string-db.org/network/171101.spr1597Hypothetical protein.
dctA protein networkhttps://string-db.org/network/171101.spr1598Dicarboxylate/amino acid:cation (Na+ or H+) symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
spr1599 protein networkhttps://string-db.org/network/171101.spr1599Conserved hypothetical protein.
spr1600 protein networkhttps://string-db.org/network/171101.spr1600Conserverd hypothetical protein; Probable transcription regulator.
spr1601 protein networkhttps://string-db.org/network/171101.spr1601Hypothetical protein.
trxA protein networkhttps://string-db.org/network/171101.spr1602Thioredoxin reductase; Belongs to the thioredoxin family.
queF protein networkhttps://string-db.org/network/171101.spr1603Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. Que [...]
aqpZ protein networkhttps://string-db.org/network/171101.spr1604Aquaporin Z - water channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
spr1605 protein networkhttps://string-db.org/network/171101.spr1605Hypothetical protein.
pepF protein networkhttps://string-db.org/network/171101.spr1606Similar to oligoendopeptidase.
spr1607 protein networkhttps://string-db.org/network/171101.spr1607Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
prmA protein networkhttps://string-db.org/network/171101.spr1608Ribosomal protein methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
mutT-2 protein networkhttps://string-db.org/network/171101.spr16097,8-dihydro-8-oxoguanine-triphosphatase.
spr1610 protein networkhttps://string-db.org/network/171101.spr1610Hypothetical protein.
spr1611 protein networkhttps://string-db.org/network/171101.spr1611Hypothetical protein.
spr1612 protein networkhttps://string-db.org/network/171101.spr1612Conserved hypothetical protein.
spr1613 protein networkhttps://string-db.org/network/171101.spr1613Hypothetical protein.
spr1614 protein networkhttps://string-db.org/network/171101.spr1614Hypothetical protein.
spr1615 protein networkhttps://string-db.org/network/171101.spr1615Hypothetical protein.
cshA protein networkhttps://string-db.org/network/171101.spr1616Chromosome segregation helicase.
sacA protein networkhttps://string-db.org/network/171101.spr1617Sucrose-6-phosphate hydrolase; Belongs to the glycosyl hydrolase 32 family.
ABC-MSP-18 protein networkhttps://string-db.org/network/171101.spr1618ABC transporter membrane-spanning permease - sugar transport.
ABC-MSP-19 protein networkhttps://string-db.org/network/171101.spr1619ABC transporter membrane-spanning permease - sugar transporter.
ABC-SBP-10 protein networkhttps://string-db.org/network/171101.spr1620ABC transporter substrate-binding protein - sugar transport.
scrR-2 protein networkhttps://string-db.org/network/171101.spr1621Sucrose operon repressor (SCR operon regulatory protein).
spr1622 protein networkhttps://string-db.org/network/171101.spr1622Conserved hypothetical protein; Putative regulator protein.
spr1623 protein networkhttps://string-db.org/network/171101.spr1623Hypothetical protein.
spr1624 protein networkhttps://string-db.org/network/171101.spr1624Conserved hypothetical protein.
spr1625 protein networkhttps://string-db.org/network/171101.spr1625Conserved hypothetical protein.
spr1626 protein networkhttps://string-db.org/network/171101.spr1626Hypothetical protein; Belongs to the UPF0337 (CsbD) family.
spr1627 protein networkhttps://string-db.org/network/171101.spr1627Conserved hypothetical protein; Probable acetyltransferase.
pilD protein networkhttps://string-db.org/network/171101.spr1628Type 4 prepilin peptidase.
spr1629 protein networkhttps://string-db.org/network/171101.spr1629Conserved hypothetical protein; Putative DNA-binding protein.
spr1630 protein networkhttps://string-db.org/network/171101.spr1630Hypothetical protein.
trpA protein networkhttps://string-db.org/network/171101.spr1631Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
trpB protein networkhttps://string-db.org/network/171101.spr1632Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpF protein networkhttps://string-db.org/network/171101.spr1633Phosphoribosylanthranilate isomerase; Belongs to the TrpF family.
trpC protein networkhttps://string-db.org/network/171101.spr1634Indole-3-glycerol-phosphate synthase; Belongs to the TrpC family.
trpD protein networkhttps://string-db.org/network/171101.spr1635Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranila [...]
trpG protein networkhttps://string-db.org/network/171101.spr1636Anthranilate synthase component II (glutamine amido-transferase).
trpE protein networkhttps://string-db.org/network/171101.spr1637Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first [...]
spr1638 protein networkhttps://string-db.org/network/171101.spr1638Hypothetical protein.
ccpA protein networkhttps://string-db.org/network/171101.spr1639Catabolite control protein.
spr1640 protein networkhttps://string-db.org/network/171101.spr1640Hypothetical protein.
mgtC protein networkhttps://string-db.org/network/171101.spr1641Mg(2+) transport ATPase/permease.
ABC-MSP-20 protein networkhttps://string-db.org/network/171101.spr1643ABC transporter membrane-spanning permease - unknown substrate.
ABC-NBD-26 protein networkhttps://string-db.org/network/171101.spr1644ABC transporter ATP-binding protein - unknown substrate; Belongs to the ABC transporter superfamily.
ABC-SBP-11 protein networkhttps://string-db.org/network/171101.spr1645ABC transporter substrate-binding protein - unknown substrate.
spr1646 protein networkhttps://string-db.org/network/171101.spr1646Hypothetical protein.
galE-2 protein networkhttps://string-db.org/network/171101.spr1647UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
galT protein networkhttps://string-db.org/network/171101.spr1648Galactose-1-phosphate uridylyltransferase.
spr1649 protein networkhttps://string-db.org/network/171101.spr1649Conserved hypothetical protein; Putative transcriptional regulator (phoU like).
spr1650 protein networkhttps://string-db.org/network/171101.spr1650Hypothetical protein.
spr1651 protein networkhttps://string-db.org/network/171101.spr1651Hypothetical protein.
pfbA protein networkhttps://string-db.org/network/171101.spr1652Hypothetical protein; Acts as a fibronectin-dependent adhesin and invasin. Binds host (in this case human) fibronectin, plasmin, plasminogen, and human serum albumin. Where the bacteria adhere to [...]
spr1654 protein networkhttps://string-db.org/network/171101.spr1654Conserved hypothetical protein; Putative role in biosynthesis of amino sugar; Belongs to the DegT/DnrJ/EryC1 family.
spr1655 protein networkhttps://string-db.org/network/171101.spr1655Conserved hypothetical protein; Putative glycosyltransferase.
ABC-N/P-5 protein networkhttps://string-db.org/network/171101.spr1656ABC transporter ATP-binding/membrane spanning protein - unknown substrate.
ABC-N/P-6 protein networkhttps://string-db.org/network/171101.spr1657ABC transporter ATP-binding/membrane spanning protein - unknown substrate.
spr1658 protein networkhttps://string-db.org/network/171101.spr1658Conserved hypothetical protein.
spr1659 protein networkhttps://string-db.org/network/171101.spr1659Hypothetical protein.
exoA protein networkhttps://string-db.org/network/171101.spr1660Exodeoxyribonuclease; In addition to 3'- to 5'-exonuclease and 3'-phosphatase activities, ExoA was shown to make single-strand breaks at apurinic sites in DNA; Belongs to the DNA repair enzymes A [...]
spr1661 protein networkhttps://string-db.org/network/171101.spr1661Hypothetical protein.
xpt protein networkhttps://string-db.org/network/171101.spr1662Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
pbuX protein networkhttps://string-db.org/network/171101.spr1663Nucleobase:cation symporter for xanthine.
dpnD protein networkhttps://string-db.org/network/171101.spr1664Restriction system of S. pneumoniae.
dpnC protein networkhttps://string-db.org/network/171101.spr1665Type II restriction enzyme DpnI (dpnC); Recognizes the double-stranded and methylated sequence G(Me)ATC and cleaves after A-2.
spr1666 protein networkhttps://string-db.org/network/171101.spr1666Conserved hypothetical protein; Similar to E. coli PaaI protein involved in phenylacetic acid degradation.
galT-2 protein networkhttps://string-db.org/network/171101.spr1667Galactose-1-phosphate uridylyltransferase.
galK protein networkhttps://string-db.org/network/171101.spr1668Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
galR protein networkhttps://string-db.org/network/171101.spr1669GalR, member of GalR-LacI family of transcriptional regulators, binds DNA; regulator of gal operon.
adhB protein networkhttps://string-db.org/network/171101.spr1670Alcohol dehydrogenase.
spr1671 protein networkhttps://string-db.org/network/171101.spr1671Conserved hypothetical protein; Similar to transcriptional regulator (MerR family).
czcD protein networkhttps://string-db.org/network/171101.spr1672Cation diffusion facilitator transporter - heavy metal transport.
spr1673 protein networkhttps://string-db.org/network/171101.spr1673Conserved hypothetical protein; Putative tetR-family transcriptional regulator.
spr1674 protein networkhttps://string-db.org/network/171101.spr1674Conserved hypothetical protein.
IS1167-6 protein networkhttps://string-db.org/network/171101.spr1675Transposase (orf1).
spr1676 protein networkhttps://string-db.org/network/171101.spr1676Degenerate transposase (orf2).
proWX protein networkhttps://string-db.org/network/171101.spr1677ABC transporter membrane-spanning permease - choline transporter.
proV protein networkhttps://string-db.org/network/171101.spr1678ABC transporter ATP-binding protein - choline transporter.
spr1679 protein networkhttps://string-db.org/network/171101.spr1679Hypothetical protein.
spr1680 protein networkhttps://string-db.org/network/171101.spr1680Hypothetical protein; Putative transcriptional regulator.
spr1681 protein networkhttps://string-db.org/network/171101.spr1681Hypothetical protein.
pepA protein networkhttps://string-db.org/network/171101.spr1682Glutamyl aminopeptidase.
spr1683 protein networkhttps://string-db.org/network/171101.spr1683UDP-galactose 4-epimerase, truncation.
fatD protein networkhttps://string-db.org/network/171101.spr1684ABC transporter membrane-spanning permease - ferric iron transport; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
fatC protein networkhttps://string-db.org/network/171101.spr1685ABC transporter membrane-spanning permease - ferric iron transport; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
fecE protein networkhttps://string-db.org/network/171101.spr1686ABC transporter ATP-binding protein - ferric iron transport.
fatB protein networkhttps://string-db.org/network/171101.spr1687ABC transporter substrate-binding protein - ferric iron transport.
spr1688 protein networkhttps://string-db.org/network/171101.spr1688Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
rluB protein networkhttps://string-db.org/network/171101.spr1689Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family.
scpB protein networkhttps://string-db.org/network/171101.spr1690Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from m [...]
scpA protein networkhttps://string-db.org/network/171101.spr1691Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from m [...]
xerD-2 protein networkhttps://string-db.org/network/171101.spr1692Recombinase, site specific; Putative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site.
spr1693 protein networkhttps://string-db.org/network/171101.spr1693Conserved hypothetical protein.
spr1694 protein networkhttps://string-db.org/network/171101.spr1694Conserved hypothetical protein.
spr1695 protein networkhttps://string-db.org/network/171101.spr1695Hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides [...]
murI protein networkhttps://string-db.org/network/171101.spr1696Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
spr1697 protein networkhttps://string-db.org/network/171101.spr1697Hypothetical protein.
dexS protein networkhttps://string-db.org/network/171101.spr1698Dextran glucosidase; Also highly similar to trehalose-6-phosphate hydrolase.
treP protein networkhttps://string-db.org/network/171101.spr1699Phosphotransferase system, trehalose-specific IIBC component.
treR protein networkhttps://string-db.org/network/171101.spr1700Trehalose operon transcriptional repressor.
spr1701 protein networkhttps://string-db.org/network/171101.spr1701Degenerate transposase (orf1).
spr1702 protein networkhttps://string-db.org/network/171101.spr1702Degenerate transposase (orf2).
amiF protein networkhttps://string-db.org/network/171101.spr1703ABC transporter ATP-binding protein - oligopeptide transport; Belongs to the ABC transporter superfamily.
amiE protein networkhttps://string-db.org/network/171101.spr1704ABC transporter ATP-binding protein - oligopeptide transport; Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport s [...]
amiD protein networkhttps://string-db.org/network/171101.spr1705ABC transporter membrane-spanning permease - oligopeptide transport; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the su [...]
amiC protein networkhttps://string-db.org/network/171101.spr1706ABC transporter membrane-spanning permease - oligopeptide transport; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the su [...]
amiA protein networkhttps://string-db.org/network/171101.spr1707ABC transporter substrate-binding protein - oligopeptide transport.
spr1708 protein networkhttps://string-db.org/network/171101.spr1708Hypothetical protein.
gtfA protein networkhttps://string-db.org/network/171101.spr1709Dextransucrase (sucrose 6-glucosyltransferase).
msmG protein networkhttps://string-db.org/network/171101.spr1710ABC transporter membrane spanning permease - multiple sugars.
msmF protein networkhttps://string-db.org/network/171101.spr1711ABC transporter membrane-spanning permease - multiple sugars.
msmE protein networkhttps://string-db.org/network/171101.spr1712ABC transporter substrate-binding protein - multiple sugars.
aga protein networkhttps://string-db.org/network/171101.spr1713Alpha-galactosidase (melibiase).
msmR protein networkhttps://string-db.org/network/171101.spr1714MSM (multiple sugar metabolism) operon regulatory protein.
birA protein networkhttps://string-db.org/network/171101.spr1715Biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
spr1716 protein networkhttps://string-db.org/network/171101.spr1716Degenerate transposase (fusion of orf1 and orf2).
spr1717 protein networkhttps://string-db.org/network/171101.spr1717Conserved hypothetical protein; Similar to RNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
recX protein networkhttps://string-db.org/network/171101.spr1718Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family.
spr1719 protein networkhttps://string-db.org/network/171101.spr1719Conserved hypothetical protein; Belongs to the UPF0374 family.
spr1720 protein networkhttps://string-db.org/network/171101.spr1720Hypothetical protein.
spr1721 protein networkhttps://string-db.org/network/171101.spr1721Degenerate transposase (fusion of orf1 and orf2).
groEL protein networkhttps://string-db.org/network/171101.spr1722Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
groES protein networkhttps://string-db.org/network/171101.spr1723Cochaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
ssbB protein networkhttps://string-db.org/network/171101.spr1724Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of act [...]
ydfG protein networkhttps://string-db.org/network/171101.spr1725Oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
spr1726 protein networkhttps://string-db.org/network/171101.spr1726Conserved hypothetical protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
spr1727 protein networkhttps://string-db.org/network/171101.spr1727Conserved hypothetical protein; Similar to thioredoxin H1.
spr1728 protein networkhttps://string-db.org/network/171101.spr1728Hypothetical protein.
spr1729 protein networkhttps://string-db.org/network/171101.spr1729Conserved hypothetical protein.
spr1730 protein networkhttps://string-db.org/network/171101.spr1730Hypothetical protein.
spr1731 protein networkhttps://string-db.org/network/171101.spr1731Hypothetical protein.
spr1732 protein networkhttps://string-db.org/network/171101.spr1732Conserved hypothetical protein; Similar to bacteriocin transport permease.
spr1733 protein networkhttps://string-db.org/network/171101.spr1733Hypothetical protein.
spr1734 protein networkhttps://string-db.org/network/171101.spr1734ABC transporter ATP-binding protein - unknown substrate, truncation.
spr1735 protein networkhttps://string-db.org/network/171101.spr1735ABC transporter ATP-binding protein - unknown substrate, truncation.
spr1736 protein networkhttps://string-db.org/network/171101.spr1736ABC transporter ATP-binding protein - unknown substrate, truncation.
spr1737 protein networkhttps://string-db.org/network/171101.spr1737Conserved hypothetical protein; Putative transcriptional regulator.
spr1738 protein networkhttps://string-db.org/network/171101.spr1738Conserved hypothetical protein.
ply protein networkhttps://string-db.org/network/171101.spr1739Pneumolysin (sulfhydryl-activated toxin that lyses cholesterol containing membranes); Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. A [...]
spr1740 protein networkhttps://string-db.org/network/171101.spr1740Hypothetical protein.
spr1741 protein networkhttps://string-db.org/network/171101.spr1741Hypothetical protein.
spr1742 protein networkhttps://string-db.org/network/171101.spr1742Hypothetical protein.
spr1743 protein networkhttps://string-db.org/network/171101.spr1743Hypothetical protein.
spr1744 protein networkhttps://string-db.org/network/171101.spr1744Degenerate transposase (orf1).
spr1745 protein networkhttps://string-db.org/network/171101.spr1745Degenerate transposase (orf2).
spr1746 protein networkhttps://string-db.org/network/171101.spr1746Hypothetical protein.
spr1747 protein networkhttps://string-db.org/network/171101.spr1747Hypothetical protein.
spr1748 protein networkhttps://string-db.org/network/171101.spr1748Hypothetical protein.
spr1749 protein networkhttps://string-db.org/network/171101.spr1749Hypothetical protein.
spr1750 protein networkhttps://string-db.org/network/171101.spr1750Hypothetical protein.
spr1751 protein networkhttps://string-db.org/network/171101.spr1751Hypothetical protein.
spr1752 protein networkhttps://string-db.org/network/171101.spr1752Hypothetical protein.
spr1753 protein networkhttps://string-db.org/network/171101.spr1753Hypothetical protein.
lytA protein networkhttps://string-db.org/network/171101.spr1754Autolysin (N-acetylmuramoyl-L-alanine amidase).
spr1755 protein networkhttps://string-db.org/network/171101.spr1755Hypothetical protein.
dinF protein networkhttps://string-db.org/network/171101.spr1756DNA-damage-inducible protein.
recA protein networkhttps://string-db.org/network/171101.spr1757DNA recombination/repair; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridiz [...]
cinA protein networkhttps://string-db.org/network/171101.spr1758Competence induced protein A; Belongs to the CinA family.
lytR protein networkhttps://string-db.org/network/171101.spr1759Regulator of lytRABC operon.
spr1760 protein networkhttps://string-db.org/network/171101.spr1760Conserved hypothetical protein.
spr1761 protein networkhttps://string-db.org/network/171101.spr1761Conserved hypothetical protein.
spr1762 protein networkhttps://string-db.org/network/171101.spr1762Hypothetical protein.
plcR protein networkhttps://string-db.org/network/171101.spr1763Transcriptional activator.
spr1764 protein networkhttps://string-db.org/network/171101.spr1764Hypothetical protein.
spr1765 protein networkhttps://string-db.org/network/171101.spr1765Hypothetical protein.
spr1766 protein networkhttps://string-db.org/network/171101.spr1766Hypothetical protein.
cylM protein networkhttps://string-db.org/network/171101.spr1767CylM protein, cytolytic toxin system.
spr1768 protein networkhttps://string-db.org/network/171101.spr1768Conserved hypothetical protein; Related to Trp repressor binding protein.
spr1769 protein networkhttps://string-db.org/network/171101.spr1769Hypothetical protein.
clyB protein networkhttps://string-db.org/network/171101.spr1770ABC transporter ATP-binding/membrane-spanning - hemolysin secretion protein.
nisP protein networkhttps://string-db.org/network/171101.spr1771Subtilisin-like serine protease.
spr1772 protein networkhttps://string-db.org/network/171101.spr1772Hypothetical protein, truncation.
ABC-NBD-27 protein networkhttps://string-db.org/network/171101.spr1773ABC transporter ATP-binding protein - unknown substrate.
spr1774 protein networkhttps://string-db.org/network/171101.spr1774Hypothetical protein.
ndk protein networkhttps://string-db.org/network/171101.spr1775Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, [...]
rpoC protein networkhttps://string-db.org/network/171101.spr1776DNA-dependent RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/171101.spr1777DNA-dependent RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
hlyX protein networkhttps://string-db.org/network/171101.spr1778Hemolysin.
endA protein networkhttps://string-db.org/network/171101.spr1779DNA-entry nuclease (competence-specific nuclease); By degrading DNA that enters the cell, plays a role in the competence of cells to be transformed; Belongs to the DNA/RNA non-specific endonuclea [...]
epuA protein networkhttps://string-db.org/network/171101.spr1780Hypothetical protein.
murA protein networkhttps://string-db.org/network/171101.spr1781UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
spr1782 protein networkhttps://string-db.org/network/171101.spr1782Conserved hypothetical protein.
kdtB protein networkhttps://string-db.org/network/171101.spr1783Lipopolysaccharide core biosynthesis protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial [...]
spr1784 protein networkhttps://string-db.org/network/171101.spr1784Conserved hypothetical protein; Probable methylase.
asnA protein networkhttps://string-db.org/network/171101.spr1785Aspartate--ammonia ligase (asparagine synthetase A).
spr1787 protein networkhttps://string-db.org/network/171101.spr1787Conserved hypothetical protein; Putative transmembrane protein; Belongs to the BI1 family.
yjfA protein networkhttps://string-db.org/network/171101.spr1788Possible rRNA/tRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
acyP protein networkhttps://string-db.org/network/171101.spr1789Acylphosphate phosphohydrolase.
yidC1 protein networkhttps://string-db.org/network/171101.spr1790Conserved hypothetical protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane prot [...]
pflC protein networkhttps://string-db.org/network/171101.spr1791Pyruvate-formate lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodo [...]
lysA protein networkhttps://string-db.org/network/171101.spr1792Diaminopimelate decarboxylase.
purR protein networkhttps://string-db.org/network/171101.spr1793Activator of purine biosynthetic genes; Controls the transcription of the pur operon for purine biosynthetic genes.
cbf1 protein networkhttps://string-db.org/network/171101.spr1794Cmp-binding-factor 1.
spr1795 protein networkhttps://string-db.org/network/171101.spr1795Conserved hypothetical protein.
spr1796 protein networkhttps://string-db.org/network/171101.spr1796Conserved hypothetical protein.
rpe protein networkhttps://string-db.org/network/171101.spr1797Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
rsgA protein networkhttps://string-db.org/network/171101.spr1798Conserved hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May [...]
ksgA protein networkhttps://string-db.org/network/171101.spr1799Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a c [...]
spr1800 protein networkhttps://string-db.org/network/171101.spr1800Hypothetical protein.
ABC-NBD-28 protein networkhttps://string-db.org/network/171101.spr1801ABC transporter ATP-binding protein - unknown substrate.
spr1802 protein networkhttps://string-db.org/network/171101.spr1802Conserved hypothetical protein; Putative immunity protein.
plcR-2 protein networkhttps://string-db.org/network/171101.spr1803Transcriptional activator.
rnmV protein networkhttps://string-db.org/network/171101.spr1804Conserved hypothetical protein; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step [...]
spr1805 protein networkhttps://string-db.org/network/171101.spr1805Conserved hypothetical protein.
spr1806 protein networkhttps://string-db.org/network/171101.spr1806Hypothetical protein.
rpmH protein networkhttps://string-db.org/network/171101.spr180750S Ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
aspC-2 protein networkhttps://string-db.org/network/171101.spr1808Potential aminotransferase; See also SPR0035.
spr1809 protein networkhttps://string-db.org/network/171101.spr1809Hypothetical protein.
spr1810 protein networkhttps://string-db.org/network/171101.spr1810Conserved hypothetical protein.
spr1811 protein networkhttps://string-db.org/network/171101.spr1811Conserved hypothetical protein.
ansB protein networkhttps://string-db.org/network/171101.spr1812L-asparaginase (L-asparagine amidohydrolase).
ccpA-2 protein networkhttps://string-db.org/network/171101.spr1813Catabolite control protein A.
rr11 protein networkhttps://string-db.org/network/171101.spr1814Response regulator.
hk11 protein networkhttps://string-db.org/network/171101.spr1815Histidine kinase.
spr1816 protein networkhttps://string-db.org/network/171101.spr1816Conserved hypothetical protein.
ABC-NBD-29 protein networkhttps://string-db.org/network/171101.spr1817ABC transporter ATP binding protein - unknown substrate.
spr1818 protein networkhttps://string-db.org/network/171101.spr1818Hypothetical protein.
comX2 protein networkhttps://string-db.org/network/171101.spr1819Competence-specific global transcription modulator; Putative sigma factor.
nusG protein networkhttps://string-db.org/network/171101.spr1820Transcription antitermination factor; Participates in transcription elongation, termination and antitermination.
secE protein networkhttps://string-db.org/network/171101.spr1821Preprotein translocase secE component; Belongs to the SecE/SEC61-gamma family.
rpmG-2 protein networkhttps://string-db.org/network/171101.spr182250S Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
pbp2a protein networkhttps://string-db.org/network/171101.spr1823Penicillin-binding protein 2a.
rluD-3 protein networkhttps://string-db.org/network/171101.spr1824Ribosomal large subunit pseudouridine synthase D.
gapA protein networkhttps://string-db.org/network/171101.spr1825Glyceraldehyde 3-phosphate dehydrogenase (phosphorylating); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
spr1826 protein networkhttps://string-db.org/network/171101.spr1826Conserved hypothetical protein.
spr1827 protein networkhttps://string-db.org/network/171101.spr1827Transposase.
spr1828 protein networkhttps://string-db.org/network/171101.spr1828Transposase.
nadC protein networkhttps://string-db.org/network/171101.spr1829Probable nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
spr1830 protein networkhttps://string-db.org/network/171101.spr1830Conserved hypothetical protein; Putative integral membrane protein.
spr1832 protein networkhttps://string-db.org/network/171101.spr1832Conserved hypothetical protein; Putative transcription regulator.
bgl2 protein networkhttps://string-db.org/network/171101.spr1833Beta-glucosidase; Belongs to the glycosyl hydrolase 1 family.
ptcC protein networkhttps://string-db.org/network/171101.spr1834Phosphotransferase system system, cellobiose-specific IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, cataly [...]
ptcB protein networkhttps://string-db.org/network/171101.spr1835Phosphotransferase system system, cellobiose-specific IIB component.
ptcA protein networkhttps://string-db.org/network/171101.spr1836Phosphotransferase system system, cellobiose-specific IIA component.
adhE protein networkhttps://string-db.org/network/171101.spr1837Alcohol-acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
spr1838 protein networkhttps://string-db.org/network/171101.spr1838Hypothetical protein.
spr1839 protein networkhttps://string-db.org/network/171101.spr1839Conserved hypothetical protein; Putative protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
YajC protein networkhttps://string-db.org/network/171101.spr1840Conserved hypothetical protein.
tktA protein networkhttps://string-db.org/network/171101.spr1841Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
spr1842 protein networkhttps://string-db.org/network/171101.spr1842Conserved hypothetical protein.
spr1843 protein networkhttps://string-db.org/network/171101.spr1843Conserved hypothetical protein; Putative transcriptional regulator.
araD protein networkhttps://string-db.org/network/171101.spr1844L-ribulose 5-phosphate 4-epimerase.
sga protein networkhttps://string-db.org/network/171101.spr1845Hexulose-6-phosphate isomerase.
sgh protein networkhttps://string-db.org/network/171101.spr1846Hexulose-6-phosphate synthase (HumpS).
PTS-EII-16 protein networkhttps://string-db.org/network/171101.spr1847Phosphotransferase system sugar-specific EII component.
PTS-EII-17 protein networkhttps://string-db.org/network/171101.spr1848Phosphotransferase system sugar-specific EII component.
PTS-EII-18 protein networkhttps://string-db.org/network/171101.spr1849Phosphotransferase system sugar-specific EII component.
spr1850 protein networkhttps://string-db.org/network/171101.spr1850Hypothetical protein.
spr1851 protein networkhttps://string-db.org/network/171101.spr1851Hypothetical protein.
yidC2 protein networkhttps://string-db.org/network/171101.spr1852Conserved hypothetical protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane prot [...]
rnpA protein networkhttps://string-db.org/network/171101.spr1853Ribonuclease P - protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RN [...]
ackA protein networkhttps://string-db.org/network/171101.spr1854Acetate kinase (acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
spr1855 protein networkhttps://string-db.org/network/171101.spr1855Conserved hypothetical protein.
spr1856 protein networkhttps://string-db.org/network/171101.spr1856Hypothetical protein.
spr1857 protein networkhttps://string-db.org/network/171101.spr1857Hypothetical protein.
spr1858 protein networkhttps://string-db.org/network/171101.spr1858Hypothetical protein.
spr1859 protein networkhttps://string-db.org/network/171101.spr1859Conserved hypothetical protein; Competence induced; related to comYD.
cglD protein networkhttps://string-db.org/network/171101.spr1861Competence induced; comG-like protein D.
cglC protein networkhttps://string-db.org/network/171101.spr1862Competence induced; comG-like protein C.
cglB protein networkhttps://string-db.org/network/171101.spr1863Competence induced; comG-like protein B.
cglA protein networkhttps://string-db.org/network/171101.spr1864Competence induced; comG-like protein A; Also known as cilD.
spr1865 protein networkhttps://string-db.org/network/171101.spr1865Conserved hypothetical protein; Putative DNA binding protein.
adh protein networkhttps://string-db.org/network/171101.spr1866Putative alcohol dehydrogenase.
nagA protein networkhttps://string-db.org/network/171101.spr1867N-acetylglucosamine-6-phosphate deacetylase.
spr1868 protein networkhttps://string-db.org/network/171101.spr1868Hypothetical protein.
tgt protein networkhttps://string-db.org/network/171101.spr1869tRNA-guanine transglycosylase (guanine insertion enzyme); Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anti [...]
spr1870 protein networkhttps://string-db.org/network/171101.spr1870Hypothetical protein.
spr1871 protein networkhttps://string-db.org/network/171101.spr1871Pyrrolidone carboxyl peptidase, truncation.
spr1872 protein networkhttps://string-db.org/network/171101.spr1872Pyrrolidone carboxyl peptidase, truncation.
spr1873 protein networkhttps://string-db.org/network/171101.spr1873Conserved hypothetical protein.
marR-2 protein networkhttps://string-db.org/network/171101.spr1874Transcriptional regulator - MarR family.
spr1875 protein networkhttps://string-db.org/network/171101.spr1875Conserved hypothetical protein; Probable group B streptococcal surface immunogenic protein.
spr1876 protein networkhttps://string-db.org/network/171101.spr1876Hypothetical protein; Low similarity to phosphoglycolate phosphatase.
spr1877 protein networkhttps://string-db.org/network/171101.spr1877Multi antimicrobial extrusion (MATE) family transporter.
thrC protein networkhttps://string-db.org/network/171101.spr1878Threonine synthase.
spr1879 protein networkhttps://string-db.org/network/171101.spr1879Hypothetical protein.
spr1880 protein networkhttps://string-db.org/network/171101.spr1880Conserved hypothetical protein; Low similarity to cytidine/deoxycytidylate deaminases.
gltX protein networkhttps://string-db.org/network/171101.spr1881Glutamyl-tRNA synthetase (glutamate--tRNA ligase); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transfe [...]
gpi protein networkhttps://string-db.org/network/171101.spr1882Glucose-6-phosphate isomerase.
spr1883 protein networkhttps://string-db.org/network/171101.spr1883Hypothetical protein.
guaA-2 protein networkhttps://string-db.org/network/171101.spr1884Glutamine amidotransferase.
ABC-NP-3 protein networkhttps://string-db.org/network/171101.spr1885ABC transporter ATP-binding/membrane spanning protein - unknown substrate.
spr1886 protein networkhttps://string-db.org/network/171101.spr1886Degenerate transposase.
ABC-NP-4 protein networkhttps://string-db.org/network/171101.spr1887ABC transporter ATP-binding/membrane spanning protein - unknown substrate.
hexA protein networkhttps://string-db.org/network/171101.spr1888DNA mismatch repair protein HexA; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step.
argR-2 protein networkhttps://string-db.org/network/171101.spr1889Arginine repressor; Regulates arginine biosynthesis genes.
argS protein networkhttps://string-db.org/network/171101.spr1890Arginyl-tRNA synthetase(arginine--tRNA ligase) (ARGRS).
IS1381-5 protein networkhttps://string-db.org/network/171101.spr1891Tranposase (orf2).
spr1892 protein networkhttps://string-db.org/network/171101.spr1892Conserved hypothetical protein.
phoP protein networkhttps://string-db.org/network/171101.spr1893Response regulator.
phoR protein networkhttps://string-db.org/network/171101.spr1894Histidine kinase.
pstS-2 protein networkhttps://string-db.org/network/171101.spr1895ABC transporter substrate-binding protein - phosphate transport; Part of the ABC transporter complex PstSACB involved in phosphate import.
pstC-2 protein networkhttps://string-db.org/network/171101.spr1896ABC transporter membrane-spanning permease - phosphate transport; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate [...]
pstA-2 protein networkhttps://string-db.org/network/171101.spr1897ABC transporter membrane-spanning permease - phosphate transport.
pstB-3 protein networkhttps://string-db.org/network/171101.spr1898ABC transporter ATP-binding protein - phosphate transport; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belon [...]
phoU-2 protein networkhttps://string-db.org/network/171101.spr1899Negative regulator of pho regulon for phosphate transport; Plays a role in the regulation of phosphate uptake.
spr1900 protein networkhttps://string-db.org/network/171101.spr1900Transposase, IS1380-Spn1 related, truncation.
spr1901 protein networkhttps://string-db.org/network/171101.spr1901Hypothetical protein; Possible transcriptional regulator.
gpdA protein networkhttps://string-db.org/network/171101.spr1902Glycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
galU protein networkhttps://string-db.org/network/171101.spr1903UTP-glucose-1-phosphate uridylyltransferase.
spr1904 protein networkhttps://string-db.org/network/171101.spr1904Conserved hypothetical protein.
spr1905 protein networkhttps://string-db.org/network/171101.spr1905Conserved hypothetical protein; Similar to 5-formyltetrahydrofolate cyclo-ligase.
hipO protein networkhttps://string-db.org/network/171101.spr1906Similar to several hippurate hydrolases and amino acid amidohydrolases; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
dapD protein networkhttps://string-db.org/network/171101.spr19072,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase-related protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
spr1908 protein networkhttps://string-db.org/network/171101.spr1908Conserved hypothetical protein.
pbp1b protein networkhttps://string-db.org/network/171101.spr1909Penicillin-binding protein 1b.
tyrS protein networkhttps://string-db.org/network/171101.spr1910Tyrosyl-tRNA synthetase 1; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end o [...]
ctpC protein networkhttps://string-db.org/network/171101.spr1911P-type ATPase - metal/cation transport.
spr1912 protein networkhttps://string-db.org/network/171101.spr1912Hypothetical protein.
rrmA protein networkhttps://string-db.org/network/171101.spr191323S rRNA m1G745 methyltransferase.
spr1914 protein networkhttps://string-db.org/network/171101.spr1914Hypothetical protein.
spr1915 protein networkhttps://string-db.org/network/171101.spr1915Hypothetical protein.
malP protein networkhttps://string-db.org/network/171101.spr1916Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural s [...]
malM protein networkhttps://string-db.org/network/171101.spr19174-alpha-glucanotransferase (amylomaltase); Belongs to the disproportionating enzyme family.
malX protein networkhttps://string-db.org/network/171101.spr1918ABC transporter substrate-binding protein - maltose/maltodextrin; Binding protein for maltose and maltodextrin; involved in its cellular uptake.
malC protein networkhttps://string-db.org/network/171101.spr1919ABC transporter membrane-spanning permease - maltose/maltodextrin; Part of the binding-protein-dependent transport system for maltodextrin; probably responsible for the translocation of the subst [...]
malD protein networkhttps://string-db.org/network/171101.spr1920ABC transporter membrane-spanning permease - maltose/maltodextrin; Part of the binding-protein-dependent transport system for maltodextrin; probably responsible for the translocation of the subst [...]
malA protein networkhttps://string-db.org/network/171101.spr1921MalA protein; Has a role in maltotetraose utilization.
malR protein networkhttps://string-db.org/network/171101.spr1922Maltose operon transcriptional repressor; Transcriptional repressor of the maltosaccharide utilization operons malxCD and malMP.
spr1923 protein networkhttps://string-db.org/network/171101.spr1923Conserved hypothetical protein.
aspS protein networkhttps://string-db.org/network/171101.spr1924Aspartyl-tRNA synthetase (aspartate-tRNA ligase); Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then tran [...]
spr1925 protein networkhttps://string-db.org/network/171101.spr1925Hypothetical protein.
spr1926 protein networkhttps://string-db.org/network/171101.spr1926Hypothetical protein.
spr1927 protein networkhttps://string-db.org/network/171101.spr1927Hypothetical protein.
spr1928 protein networkhttps://string-db.org/network/171101.spr1928Hypothetical protein.
spr1929 protein networkhttps://string-db.org/network/171101.spr1929Conserved hypothetical protein; Putative transcriptional repressor protein.
spr1930 protein networkhttps://string-db.org/network/171101.spr1930Hypothetical protein.
hisS protein networkhttps://string-db.org/network/171101.spr1931Histidyl-tRNA synthetase.
spr1932 protein networkhttps://string-db.org/network/171101.spr1932Conserved hypothetical protein; Putative permease.
rgg protein networkhttps://string-db.org/network/171101.spr1933Positive transcriptional regulator of glucosyltransferase and Spp phenotype.
spr1934 protein networkhttps://string-db.org/network/171101.spr1934Conserved hypothetical protein.
ilvD protein networkhttps://string-db.org/network/171101.spr1935Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
tktC protein networkhttps://string-db.org/network/171101.spr1936Putative transketolase c-terminal section.
tktN protein networkhttps://string-db.org/network/171101.spr1937Putative transketolase n-terminal section.
UlaA protein networkhttps://string-db.org/network/171101.spr1938Conserved hypothetical protein; Putative transporter.
spr1939 protein networkhttps://string-db.org/network/171101.spr1939Hypothetical protein.
spr1940 protein networkhttps://string-db.org/network/171101.spr1940Conserved hypothetical protein; Probable transcriptional antiterminator, bglG family.
spr1941 protein networkhttps://string-db.org/network/171101.spr1941Hypothetical protein.
spr1942 protein networkhttps://string-db.org/network/171101.spr1942Hypothetical protein.
rpmF protein networkhttps://string-db.org/network/171101.spr194350S Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
rpmG3 protein networkhttps://string-db.org/network/171101.spr194450S Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
pcpA protein networkhttps://string-db.org/network/171101.spr1945Choline-binding protein.
spr1946 protein networkhttps://string-db.org/network/171101.spr1946Degenerate transposase (orf1).
IS1381-6 protein networkhttps://string-db.org/network/171101.spr1947Tranposase (orf2).
spr1949 protein networkhttps://string-db.org/network/171101.spr1949Hypothetical protein.
spr1950 protein networkhttps://string-db.org/network/171101.spr1950Conserved hypothetical protein; Putative sugar operon regulatory protein.
spr1951 protein networkhttps://string-db.org/network/171101.spr1951Conserved hypothetical protein; Probable sugar hydrolase.
spr1952 protein networkhttps://string-db.org/network/171101.spr1952Conserved hypothetical protein.
spr1953 protein networkhttps://string-db.org/network/171101.spr1953Conserved hypothetical protein; Similar to a sugar hydrolase in Lactococcus lactis subsp. lactis.
spr1954 protein networkhttps://string-db.org/network/171101.spr1954Hypothetical protein.
spr1955 protein networkhttps://string-db.org/network/171101.spr1955Arginine deiminase, truncation.
spr1956 protein networkhttps://string-db.org/network/171101.spr1956Arginine deiminase, truncation.
arcB protein networkhttps://string-db.org/network/171101.spr1957Ornithine transcarbamoylase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to t [...]
arcC protein networkhttps://string-db.org/network/171101.spr1958Carbamate kinase; Belongs to the carbamate kinase family.
spr1959 protein networkhttps://string-db.org/network/171101.spr1959Conserved hypothetical integral membrane protein.
spr1960 protein networkhttps://string-db.org/network/171101.spr1960Conserved hypothetical protein; Probable Xaa-His dipeptidase.
spr1961 protein networkhttps://string-db.org/network/171101.spr1961Hypothetical protein.
spr1962 protein networkhttps://string-db.org/network/171101.spr1962Conserved hypothetical protein; Probable member of SPFH domain/Band 7 family.
adh2 protein networkhttps://string-db.org/network/171101.spr1963Probable alcohol dehydrogenase.
fucI protein networkhttps://string-db.org/network/171101.spr1964L-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose.
spr1965 protein networkhttps://string-db.org/network/171101.spr1965Hypothetical protein.
spr1966 protein networkhttps://string-db.org/network/171101.spr1966Conserved hypothetical protein.
PTS-EII-19 protein networkhttps://string-db.org/network/171101.spr1967Phosphotransferase system sugar-specific EII component.
PTS-EII-20 protein networkhttps://string-db.org/network/171101.spr1968Phosphotransferase system sugar-specific EII component.
PTS-EII-21 protein networkhttps://string-db.org/network/171101.spr1969Phosphotransferase system sugar-specific EII component.
PTS-EII-22 protein networkhttps://string-db.org/network/171101.spr1970Phosphotransferase system sugar-specific EII component.
fucU protein networkhttps://string-db.org/network/171101.spr1971Fucose pathway protein, function unknown; Belongs to the RbsD / FucU family.
fucA protein networkhttps://string-db.org/network/171101.spr1972L-fuculose phosphate aldolase.
fcsK protein networkhttps://string-db.org/network/171101.spr1973Fucose kinase.
fcsR protein networkhttps://string-db.org/network/171101.spr1974Regulator of fucose operon.
adcA protein networkhttps://string-db.org/network/171101.spr1975ABC transporter substrate-binding protein - Zinc (Zn2+) transport; Part of the ATP-driven transport system AdcABC for zinc. Required for transformability; Belongs to the bacterial solute-binding [...]
adcB protein networkhttps://string-db.org/network/171101.spr1976ABC transporter membrane-spanning permease - Zinc (Zn2+) transport.
adcC protein networkhttps://string-db.org/network/171101.spr1977ABC transporter ATP-binding domain - Zinc (Zn2+) permease; Part of the ATP-driven transport system AdcABC for zinc. Required for transformability (By similarity).
adcR protein networkhttps://string-db.org/network/171101.spr1978Transcriptional repressor for Zn(2+)-responsive expression.
dltD protein networkhttps://string-db.org/network/171101.spr1979D-alanine transfer from undecaprenol-phosphate to the poly(glycerophosphate) chain.
dltC protein networkhttps://string-db.org/network/171101.spr1980D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier [...]
dltB protein networkhttps://string-db.org/network/171101.spr1981D-alanine transfer from Dcp to undecaprenol-phosphate; Could be involved in the transport of activated D-alanine through the membrane.
dltA protein networkhttps://string-db.org/network/171101.spr1982D-alanine-D-alanyl carrier protein ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protei [...]
spr1983 protein networkhttps://string-db.org/network/171101.spr1983Conserved hypothetical protein.
spr1984 protein networkhttps://string-db.org/network/171101.spr1984Transposase, uncharacterized, truncation.
spr1985 protein networkhttps://string-db.org/network/171101.spr1985Transposase, uncharacterized, truncation.
spr1987 protein networkhttps://string-db.org/network/171101.spr1987Hypothetical protein, truncation.
glpF-2 protein networkhttps://string-db.org/network/171101.spr1988Glycerol uptake facilitator protein; Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic mem [...]
spr1989 protein networkhttps://string-db.org/network/171101.spr1989Glycerol-3-phosphate dehydrogenase, truncation.
spr1990 protein networkhttps://string-db.org/network/171101.spr1990Glycerol-3-phosphate dehydrogenase, truncation.
glpK protein networkhttps://string-db.org/network/171101.spr1991Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
spr1992 protein networkhttps://string-db.org/network/171101.spr1992Hypothetical protein.
hsp33 protein networkhttps://string-db.org/network/171101.spr1993Chaperonin (heat shock protein 33); Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role [...]
spr1994 protein networkhttps://string-db.org/network/171101.spr1994Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines [...]
pspC protein networkhttps://string-db.org/network/171101.spr1995Choline binding protein A.
spr1996 protein networkhttps://string-db.org/network/171101.spr1996Conserved hypothetical protein.
hk06 protein networkhttps://string-db.org/network/171101.spr1997Histidine kinase.
rr06 protein networkhttps://string-db.org/network/171101.spr1998Response regulator.
spr1999 protein networkhttps://string-db.org/network/171101.spr1999Class III stress response-related ATPase, truncation.
spr2000 protein networkhttps://string-db.org/network/171101.spr2000Class III stress response-related ATPase, truncation; Belongs to the ClpA/ClpB family.
ctsR protein networkhttps://string-db.org/network/171101.spr2001Transcriptional regulator CtsR; Belongs to the CtsR family.
ABC-NBD-30 protein networkhttps://string-db.org/network/171101.spr2002ABC transporter ATP-binding protein - anion transport.
spr2003 protein networkhttps://string-db.org/network/171101.spr2003Conserved hypothetical protein.
ABC-MSP-21 protein networkhttps://string-db.org/network/171101.spr2004ABC transporter membrane-spanning permease - unknown substrate.
spr2005 protein networkhttps://string-db.org/network/171101.spr2005Conserved hypothetical protein.
cbpD protein networkhttps://string-db.org/network/171101.spr2006Choline binding protein D.
spr2007 protein networkhttps://string-db.org/network/171101.spr2007Conserved hypothetical protein.
dnaC protein networkhttps://string-db.org/network/171101.spr2008Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
rplI protein networkhttps://string-db.org/network/171101.spr200950S Ribosomal protein subunit L9; Binds to the 23S rRNA.
spr2010 protein networkhttps://string-db.org/network/171101.spr2010Conserved hypothetical protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
hpf protein networkhttps://string-db.org/network/171101.spr2011Conserved hypothetical protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during [...]
comFC protein networkhttps://string-db.org/network/171101.spr2012Involved in transformation (competence for DNA uptake).
comFA protein networkhttps://string-db.org/network/171101.spr2013Involved in transformation; required for DNA uptake but not for binding; Related to ATP-dependent RNA/DNA helicases.
spr2014 protein networkhttps://string-db.org/network/171101.spr2014Conserved hypothetical protein.
cycK protein networkhttps://string-db.org/network/171101.spr2015Cysteine synthase, O-acetylserine sulfhydrylase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
Transposase_G protein networkhttps://string-db.org/network/171101.spr2016Transposase, uncharacterized, truncation.
spr2017 protein networkhttps://string-db.org/network/171101.spr2017Degenerate transposase.
spr2018 protein networkhttps://string-db.org/network/171101.spr2018Degenerate transposase.
tsf protein networkhttps://string-db.org/network/171101.spr2019Elongation factor TS; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the [...]
rpsB protein networkhttps://string-db.org/network/171101.spr202030S Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
gsp-781 protein networkhttps://string-db.org/network/171101.spr2021General stress protein GSP-781.
mreD protein networkhttps://string-db.org/network/171101.spr2022Cell-shape determining protein MreD.
mreC protein networkhttps://string-db.org/network/171101.spr2023Cell shape determining protein MreC; Involved in formation and maintenance of cell shape.
ABC-MSP-22 protein networkhttps://string-db.org/network/171101.spr2024ABC transporter membrane-spanning permease - unknown substrate; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF tr [...]
ABC-NBP protein networkhttps://string-db.org/network/171101.spr2025ABC transporter ATP-binding protein - unknown substrate; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF trans [...]
stpA protein networkhttps://string-db.org/network/171101.spr2026ABC transporter ATP-binding protein - unknown substrate; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF trans [...]
pgsA protein networkhttps://string-db.org/network/171101.spr2027Phosphotidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
spr2028 protein networkhttps://string-db.org/network/171101.spr2028Conserved hypothetical protein.
spr2029 protein networkhttps://string-db.org/network/171101.spr2029Conserved hypothetical protein; Probable protease/peptidase.
spr2030 protein networkhttps://string-db.org/network/171101.spr2030Conserved hypothetical protein.
spr2031 protein networkhttps://string-db.org/network/171101.spr2031Conserved hypothetical protein.
recF protein networkhttps://string-db.org/network/171101.spr2032Recombination protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DN [...]
imdH protein networkhttps://string-db.org/network/171101.spr2033Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesi [...]
trpS protein networkhttps://string-db.org/network/171101.spr2034Tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
ABC-NBD-31 protein networkhttps://string-db.org/network/171101.spr2035ABC transporter ATP-binding protein - unknown substrate.
spr2036 protein networkhttps://string-db.org/network/171101.spr2036Conserved hypothetical protein.
spr2037 protein networkhttps://string-db.org/network/171101.spr2037Conserved hypothetical protein, truncation.
spr2038 protein networkhttps://string-db.org/network/171101.spr2038Conserved hypothetical protein, truncation.
spr2039 protein networkhttps://string-db.org/network/171101.spr2039Conserved hypothetical protein, truncation.
spr2040 protein networkhttps://string-db.org/network/171101.spr2040Conserved hypothetical protein; Probable transcriptional regulator of TetR family.
comE protein networkhttps://string-db.org/network/171101.spr2041Response regulator; Required for induction of competence.
comD protein networkhttps://string-db.org/network/171101.spr2042Histidine protein kinase; Required for induction of competence.
comC protein networkhttps://string-db.org/network/171101.spr2043Competence stimulating peptide precursor (CSP); Acts as a pheromone, induces cells to develop competence for genetic transformation; Belongs to the ComC family.
rlmH protein networkhttps://string-db.org/network/171101.spr2044Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
sphtra protein networkhttps://string-db.org/network/171101.spr2045Serine protease.
spo0J protein networkhttps://string-db.org/network/171101.spr2046Chromosome segregation protein; Belongs to the ParB family.