Organism Overview: Buchnera aphidicola Bp


 
gidA protein networkhttps://string-db.org/network/224915.bbp_001Glucose inhibited division protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2) [...]
atpB protein networkhttps://string-db.org/network/224915.bbp_002ATP synthase A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
atpE protein networkhttps://string-db.org/network/224915.bbp_003ATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembra [...]
atpF protein networkhttps://string-db.org/network/224915.bbp_004ATP synthase B chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembra [...]
atpH protein networkhttps://string-db.org/network/224915.bbp_005ATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extrame [...]
atpA protein networkhttps://string-db.org/network/224915.bbp_006ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family [...]
atpG protein networkhttps://string-db.org/network/224915.bbp_007ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of [...]
atpD protein networkhttps://string-db.org/network/224915.bbp_008ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha [...]
atpC protein networkhttps://string-db.org/network/224915.bbp_009ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.
gyrB protein networkhttps://string-db.org/network/224915.bbp_010Putative DNA gyrase subunit b; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromos [...]
dnaN protein networkhttps://string-db.org/network/224915.bbp_011Putative DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp [...]
dnaA protein networkhttps://string-db.org/network/224915.bbp_012Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically doub [...]
rpmH protein networkhttps://string-db.org/network/224915.bbp_01350S ribosomal protein L34; COG0230; Belongs to the bacterial ribosomal protein bL34 family.
rnpA protein networkhttps://string-db.org/network/224915.bbp_014Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. [...]
yidD protein networkhttps://string-db.org/network/224915.bbp_015Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
yidC protein networkhttps://string-db.org/network/224915.bbp_016Putative membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins [...]
thdF protein networkhttps://string-db.org/network/224915.bbp_017Putative tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of [...]
mutH protein networkhttps://string-db.org/network/224915.bbp_018MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family.
mopB protein networkhttps://string-db.org/network/224915.bbp_020Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
mopA protein networkhttps://string-db.org/network/224915.bbp_021Chaperonin GroEL protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
yjeK protein networkhttps://string-db.org/network/224915.bbp_022Putative aminomutase; With EpmA is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. EpmB appears to act before E [...]
efp protein networkhttps://string-db.org/network/224915.bbp_023Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by [...]
dnaC protein networkhttps://string-db.org/network/224915.bbp_024Putative DNA replication protein; This protein is required for chromosomal replication. It forms, in concert with DnaB protein and other prepriming proteins DnaT, N, N', N'' a prepriming protein [...]
yhhF protein networkhttps://string-db.org/network/224915.bbp_025Putative methylase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.
ftsY protein networkhttps://string-db.org/network/224915.bbp_026FtsY protei; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and [...]
rpoH protein networkhttps://string-db.org/network/224915.bbp_027RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involve [...]
glmS protein networkhttps://string-db.org/network/224915.bbp_028Glucosamine-fructose-6-phosphate aminotransferase isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
glmU protein networkhttps://string-db.org/network/224915.bbp_029UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyz [...]
yigL protein networkhttps://string-db.org/network/224915.bbp_030Putative haloacid dehalogenase-like hydrolase; COG0561; YigL.
metE protein networkhttps://string-db.org/network/224915.bbp_0315-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; B [...]
purH protein networkhttps://string-db.org/network/224915.bbp_032Phosphoribosylaminoimidazolecarboxamide formyltransferase; COG0138; bifunctional purine biosynthesis protein PurH; AICAR transformylase; inosinicase; IMP synthetase; ATIC.
hupA protein networkhttps://string-db.org/network/224915.bbp_033DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to [...]
rpoC protein networkhttps://string-db.org/network/224915.bbp_034DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/224915.bbp_035DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplL protein networkhttps://string-db.org/network/224915.bbp_03650S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the ba [...]
rplJ protein networkhttps://string-db.org/network/224915.bbp_03750S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal prot [...]
rplA protein networkhttps://string-db.org/network/224915.bbp_03850S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/224915.bbp_03950S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/224915.bbp_040Transcription antitermination protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA [...]
secE protein networkhttps://string-db.org/network/224915.bbp_041Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
murB protein networkhttps://string-db.org/network/224915.bbp_046UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
metF protein networkhttps://string-db.org/network/224915.bbp_0475,10-methylenetetrahydrofolate reductase; COG0685; Belongs to the methylenetetrahydrofolate reductase family.
argG protein networkhttps://string-db.org/network/224915.bbp_048Argininosuccinate synthase; COG0137; citrulline--aspartate ligase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
argH protein networkhttps://string-db.org/network/224915.bbp_049Argininosuccinate lyase; COG0165; arginosuccinase; ASAL.
yibN protein networkhttps://string-db.org/network/224915.bbp_050Hypothetical protein; COG0607.
cysE protein networkhttps://string-db.org/network/224915.bbp_051Serine acetyltransferase; COG1045; SAT.
rpoD protein networkhttps://string-db.org/network/224915.bbp_052RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the p [...]
dnaG protein networkhttps://string-db.org/network/224915.bbp_053DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpsU protein networkhttps://string-db.org/network/224915.bbp_05430S ribosomal protein S21; COG0828; Belongs to the bacterial ribosomal protein bS21 family.
gcp protein networkhttps://string-db.org/network/224915.bbp_055Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is invo [...]
ribB protein networkhttps://string-db.org/network/224915.bbp_0563,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
cca protein networkhttps://string-db.org/network/224915.bbp_057tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order [...]
bacA protein networkhttps://string-db.org/network/224915.bbp_058Bacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
crr protein networkhttps://string-db.org/network/224915.bbp_059PTS system glucose-specific IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylati [...]
ptsI protein networkhttps://string-db.org/network/224915.bbp_060Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate ac [...]
ptsH protein networkhttps://string-db.org/network/224915.bbp_061Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport syste [...]
lig protein networkhttps://string-db.org/network/224915.bbp_062DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy sourc [...]
gltX protein networkhttps://string-db.org/network/224915.bbp_065glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
fliE protein networkhttps://string-db.org/network/224915.bbp_067Flagellar hook-basal body complex protein FliE; COG1677.
fliF protein networkhttps://string-db.org/network/224915.bbp_068Flagellar M-ring protein; The M ring may be actively involved in energy transduction.
fliG protein networkhttps://string-db.org/network/224915.bbp_069Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex int [...]
fliH protein networkhttps://string-db.org/network/224915.bbp_070Flagellar assembly protein FliH; Needed for flagellar regrowth and assembly; Belongs to the FliH family.
fliI protein networkhttps://string-db.org/network/224915.bbp_071Flagellum-specific ATP synthase; Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum. May be inv [...]
fliJ protein networkhttps://string-db.org/network/224915.bbp_072Flagellar FliJ protein; Flagellar protein that affects chemotactic events. Belongs to the FliJ family.
fliK protein networkhttps://string-db.org/network/224915.bbp_073Flagellar FliK protein; Controls the length of the flagellar hook; Belongs to the FliK family.
fliM protein networkhttps://string-db.org/network/224915.bbp_074Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex int [...]
fliN protein networkhttps://string-db.org/network/224915.bbp_075Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex inte [...]
fliOP protein networkhttps://string-db.org/network/224915.bbp_076Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
fliQ protein networkhttps://string-db.org/network/224915.bbp_077Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis; Belongs to the FliQ/MopD/SpaQ family.
fliR protein networkhttps://string-db.org/network/224915.bbp_078Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis; Belongs to the FliR/MopE/SpaR family.
rpmG protein networkhttps://string-db.org/network/224915.bbp_07950S ribosomal protein L33; COG0267; Belongs to the bacterial ribosomal protein bL33 family.
rpmB protein networkhttps://string-db.org/network/224915.bbp_08050S ribosomal protein L28; COG0227; Belongs to the bacterial ribosomal protein bL28 family.
ytfN protein networkhttps://string-db.org/network/224915.bbp_081RpoD protein; COG2911.
ppa protein networkhttps://string-db.org/network/224915.bbp_082Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
pmbA protein networkhttps://string-db.org/network/224915.bbp_083PmbA protein; Probable metalloprotease; Belongs to the peptidase U62 family.
yraL protein networkhttps://string-db.org/network/224915.bbp_085Putative tetrapyrrole methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
fabB protein networkhttps://string-db.org/network/224915.bbp_0863-oxoacyl-[acyl-carrier-protein] synthase I; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongati [...]
talA protein networkhttps://string-db.org/network/224915.bbp_087Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
tktB protein networkhttps://string-db.org/network/224915.bbp_088Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
dapE protein networkhttps://string-db.org/network/224915.bbp_089Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in [...]
dapA protein networkhttps://string-db.org/network/224915.bbp_090Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
aroC protein networkhttps://string-db.org/network/224915.bbp_091Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
yb2331 protein networkhttps://string-db.org/network/224915.bbp_092Hypothetical protein; COG2840; Belongs to the UPF0115 family.
hisG protein networkhttps://string-db.org/network/224915.bbp_093ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate [...]
hisD protein networkhttps://string-db.org/network/224915.bbp_094Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
hisC protein networkhttps://string-db.org/network/224915.bbp_095Histidinol-phosphate aminotransferase; COG0079; imidazole; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
hisB protein networkhttps://string-db.org/network/224915.bbp_096Histidinol-phosphatase; COG0241; COG0131; histidine biosynthesis bifunctional protein HisB; IGPD; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
hisH protein networkhttps://string-db.org/network/224915.bbp_097Amidotransferase HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of [...]
hisA protein networkhttps://string-db.org/network/224915.bbp_098Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; COG0106.
hisF protein networkhttps://string-db.org/network/224915.bbp_099HisF protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using th [...]
hisI protein networkhttps://string-db.org/network/224915.bbp_100phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family.
gnd protein networkhttps://string-db.org/network/224915.bbp_1016-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
dcd protein networkhttps://string-db.org/network/224915.bbp_102Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
metG protein networkhttps://string-db.org/network/224915.bbp_103methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
mesJ protein networkhttps://string-db.org/network/224915.bbp_104Putative cell cycle protein MesJ; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine [...]
norM protein networkhttps://string-db.org/network/224915.bbp_106Multidrug resistance protein NorM; Multidrug efflux pump; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
ribE protein networkhttps://string-db.org/network/224915.bbp_107Riboflavin synthase alpha chain; Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil.
rnfA protein networkhttps://string-db.org/network/224915.bbp_108Electron transport complex protein RnfA; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
rnfB protein networkhttps://string-db.org/network/224915.bbp_109Electron transport complex protein RnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferred [...]
rnfC protein networkhttps://string-db.org/network/224915.bbp_110Electron transport complex protein RnfC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferred [...]
rnfD protein networkhttps://string-db.org/network/224915.bbp_111Electron transport complex protein RnfD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.
rnfG protein networkhttps://string-db.org/network/224915.bbp_112Electron transport complex protein RnfG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.
ydgQ protein networkhttps://string-db.org/network/224915.bbp_113Electron transport complex protein rnfE; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
nth protein networkhttps://string-db.org/network/224915.bbp_114Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- [...]
tyrS protein networkhttps://string-db.org/network/224915.bbp_115tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
ydiC protein networkhttps://string-db.org/network/224915.bbp_116Conserved hypothetical protein; COG0316; Belongs to the HesB/IscA family.
yb1688 protein networkhttps://string-db.org/network/224915.bbp_117Putative membrane protein; COG0628.
aroH protein networkhttps://string-db.org/network/224915.bbp_118Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate [...]
thrS protein networkhttps://string-db.org/network/224915.bbp_119threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor en [...]
infC protein networkhttps://string-db.org/network/224915.bbp_120Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enha [...]
rpmI protein networkhttps://string-db.org/network/224915.bbp_121COG0291; ribosomal protein A; Belongs to the bacterial ribosomal protein bL35 family.
rplT protein networkhttps://string-db.org/network/224915.bbp_12250S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing func [...]
pheS protein networkhttps://string-db.org/network/224915.bbp_123COG0016; phenylalanine-tRNA ligase alpha chain; PheRS; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
pheT protein networkhttps://string-db.org/network/224915.bbp_124COG0073; COG0072; phenylalanine-tRNA ligase beta chain; PheRS; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
yajC protein networkhttps://string-db.org/network/224915.bbp_125Putative membrane protein YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes [...]
glyS protein networkhttps://string-db.org/network/224915.bbp_126glycyl-tRNA synthetase beta chain (Glycine--tRNA ligase beta chain) (GlyRS); COG0751.
glyQ protein networkhttps://string-db.org/network/224915.bbp_127COG0752; glycine--tRNA ligase alpha chain; GlyRS.
nfo protein networkhttps://string-db.org/network/224915.bbp_128Putative endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal suga [...]
rplY protein networkhttps://string-db.org/network/224915.bbp_12950S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 fa [...]
yabI protein networkhttps://string-db.org/network/224915.bbp_130Putative DedA-family membrane protein; COG0586.
ksgA protein networkhttps://string-db.org/network/224915.bbp_131Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a c [...]
apaH protein networkhttps://string-db.org/network/224915.bbp_132Bis 5'-nucleosyl-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
folA protein networkhttps://string-db.org/network/224915.bbp_133Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
carB protein networkhttps://string-db.org/network/224915.bbp_134COG0458; carbamoyl- phosphate synthase (ammonia); carbamoyl-phosphate synthetase (ammonia); carbamoyl-phosphate synthetase I; carbon-dioxide-ammonia ligase; CARB.
carA protein networkhttps://string-db.org/network/224915.bbp_135Carbamoyl-phosphate synthase small chain; COG0505; carbamoyl- phosphate synthetase glutamine chain; Belongs to the CarA family.
dapB protein networkhttps://string-db.org/network/224915.bbp_136Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
lytB protein networkhttps://string-db.org/network/224915.bbp_137LytB-like protein; COG0761.
lspA protein networkhttps://string-db.org/network/224915.bbp_138Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
ileS protein networkhttps://string-db.org/network/224915.bbp_139isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
rpsT protein networkhttps://string-db.org/network/224915.bbp_14030S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
dnaJ protein networkhttps://string-db.org/network/224915.bbp_141Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an [...]
dnaK protein networkhttps://string-db.org/network/224915.bbp_142Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
nuoA protein networkhttps://string-db.org/network/224915.bbp_143NADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoB protein networkhttps://string-db.org/network/224915.bbp_144NADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation [...]
nuoCD protein networkhttps://string-db.org/network/224915.bbp_145NADH dehydrogenase I chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in [...]
nuoE protein networkhttps://string-db.org/network/224915.bbp_146NADH dehydrogenase I chain E; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation [...]
nuoF protein networkhttps://string-db.org/network/224915.bbp_147NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation [...]
nuoG protein networkhttps://string-db.org/network/224915.bbp_148NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation [...]
nuoH protein networkhttps://string-db.org/network/224915.bbp_149NADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoI protein networkhttps://string-db.org/network/224915.bbp_150NADH dehydrogenase I chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoJ protein networkhttps://string-db.org/network/224915.bbp_151NADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation [...]
nuoK protein networkhttps://string-db.org/network/224915.bbp_152NADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoL protein networkhttps://string-db.org/network/224915.bbp_153NADH dehydrogenase I chain L; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation [...]
nuoM protein networkhttps://string-db.org/network/224915.bbp_154NADH dehydrogenase subunit 4; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation [...]
nuoN protein networkhttps://string-db.org/network/224915.bbp_155NADH dehydrogenase subunit 2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
ygjT protein networkhttps://string-db.org/network/224915.bbp_156Putative transport protein; COG0861.
folC protein networkhttps://string-db.org/network/224915.bbp_157Folylpolyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate [...]
cvpA protein networkhttps://string-db.org/network/224915.bbp_158Colicin V production-like protein; COG1286.
prsA protein networkhttps://string-db.org/network/224915.bbp_159Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hy [...]
prfA protein networkhttps://string-db.org/network/224915.bbp_161Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
hemK protein networkhttps://string-db.org/network/224915.bbp_162HemK; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine met [...]
ychA protein networkhttps://string-db.org/network/224915.bbp_163Hypothetical protein ychA; COG2912; Belongs to the UPF0162 family.
ackA protein networkhttps://string-db.org/network/224915.bbp_164Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
pta protein networkhttps://string-db.org/network/224915.bbp_165Phosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family.
yfaE protein networkhttps://string-db.org/network/224915.bbp_166Putative iron-sulphur binding protein; COG0633; putative ferredoxin.
nrdB protein networkhttps://string-db.org/network/224915.bbp_167Ribonucleoside-diphosphate reductase 1 beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides ( [...]
nrdA protein networkhttps://string-db.org/network/224915.bbp_168Ribonucleoside-diphosphate reductase 1 alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [...]
gyrA protein networkhttps://string-db.org/network/224915.bbp_169DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
yba2 protein networkhttps://string-db.org/network/224915.bbp_170Hypothetical protein; COG3416.
ahpC protein networkhttps://string-db.org/network/224915.bbp_171Peroxiredoxin 2; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection agains [...]
ung protein networkhttps://string-db.org/network/224915.bbp_172uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
grpE protein networkhttps://string-db.org/network/224915.bbp_173GrpE protein 2; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucle [...]
ppnK protein networkhttps://string-db.org/network/224915.bbp_174Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically t [...]
ydhD protein networkhttps://string-db.org/network/224915.bbp_176Thioredoxin-like protein 2; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters.
rnt protein networkhttps://string-db.org/network/224915.bbp_177Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP [...]
sodA protein networkhttps://string-db.org/network/224915.bbp_178Superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase [...]
pth protein networkhttps://string-db.org/network/224915.bbp_179peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
ychF protein networkhttps://string-db.org/network/224915.bbp_180Hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OB [...]
thrC protein networkhttps://string-db.org/network/224915.bbp_181Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
thrB protein networkhttps://string-db.org/network/224915.bbp_182Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
thrA protein networkhttps://string-db.org/network/224915.bbp_183Aspartokinase; COG0527; COG0460; bifunctional aspartokinase/homoserine dehydrogenase (AK-HD); In the C-terminal section; belongs to the homoserine dehydrogenase family.
dksA protein networkhttps://string-db.org/network/224915.bbp_184DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several am [...]
truA protein networkhttps://string-db.org/network/224915.bbp_185tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
mrcB protein networkhttps://string-db.org/network/224915.bbp_186Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domai [...]
secA protein networkhttps://string-db.org/network/224915.bbp_187Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer [...]
guaC protein networkhttps://string-db.org/network/224915.bbp_188GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and [...]
aceE protein networkhttps://string-db.org/network/224915.bbp_189Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
aceF protein networkhttps://string-db.org/network/224915.bbp_190Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contain [...]
lpdA protein networkhttps://string-db.org/network/224915.bbp_191Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
pfs protein networkhttps://string-db.org/network/224915.bbp_1925'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) [...]
yadR protein networkhttps://string-db.org/network/224915.bbp_193HesB/YadR/YfhF family protein; Required for insertion of 4Fe-4S clusters for at least IspG.
ftsZ protein networkhttps://string-db.org/network/224915.bbp_194Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...]
ftsA protein networkhttps://string-db.org/network/224915.bbp_195Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
ddlB protein networkhttps://string-db.org/network/224915.bbp_196D-alanine-D-alanine ligase; Cell wall formation.
murC protein networkhttps://string-db.org/network/224915.bbp_197UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
murG protein networkhttps://string-db.org/network/224915.bbp_198Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
ftsW protein networkhttps://string-db.org/network/224915.bbp_199Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
murD protein networkhttps://string-db.org/network/224915.bbp_200UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF f [...]
mraY protein networkhttps://string-db.org/network/224915.bbp_201phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY s [...]
murF protein networkhttps://string-db.org/network/224915.bbp_202UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D- alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapepti [...]
murE protein networkhttps://string-db.org/network/224915.bbp_203UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) [...]
ftsI protein networkhttps://string-db.org/network/224915.bbp_204Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
ftsL protein networkhttps://string-db.org/network/224915.bbp_205Cell division protein FtsL-like protein; Essential cell division protein; Belongs to the FtsL family.
yabC protein networkhttps://string-db.org/network/224915.bbp_206Hypothetical protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
ilvH protein networkhttps://string-db.org/network/224915.bbp_207COG0440; AHAS; acetohydroxy-acid synthase small subunit; ALS.
ilvI protein networkhttps://string-db.org/network/224915.bbp_208COG0028; AHAS; acetohydroxy-acid synthase large subunit; ALS.
apbE protein networkhttps://string-db.org/network/224915.bbp_209Putative thiamine biosynthesis protein ApbE precursor; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residu [...]
htrA protein networkhttps://string-db.org/network/224915.bbp_210Serine protease; Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.
dapD protein networkhttps://string-db.org/network/224915.bbp_2112,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; COG2171; AHAS; acetohydroxy-acid synthase large subunit; ALS; Belongs to the transferase hexapeptide repeat family.
map protein networkhttps://string-db.org/network/224915.bbp_212Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharg [...]
rpsB protein networkhttps://string-db.org/network/224915.bbp_213Ribosomal protein S2; COG0052; Belongs to the universal ribosomal protein uS2 family.
tsf protein networkhttps://string-db.org/network/224915.bbp_214Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the [...]
pyrH protein networkhttps://string-db.org/network/224915.bbp_215Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
frr protein networkhttps://string-db.org/network/224915.bbp_216Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
uppS protein networkhttps://string-db.org/network/224915.bbp_218Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,3 [...]
fabZ protein networkhttps://string-db.org/network/224915.bbp_219(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated [...]
dnaE protein networkhttps://string-db.org/network/224915.bbp_220DNA polymerase III alpha subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exon [...]
proS protein networkhttps://string-db.org/network/224915.bbp_221prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
flhB protein networkhttps://string-db.org/network/224915.bbp_222Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of [...]
flhA protein networkhttps://string-db.org/network/224915.bbp_223Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin (By simi [...]
argS protein networkhttps://string-db.org/network/224915.bbp_224arginyl-tRNA synthetase; COG0018; arginine-tRNA ligase; ARGRS.
gloB protein networkhttps://string-db.org/network/224915.bbp_228Putative hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
rnhA protein networkhttps://string-db.org/network/224915.bbp_229Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
dnaQ protein networkhttps://string-db.org/network/224915.bbp_230Putative DNA polymerase III epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editin [...]
gpt protein networkhttps://string-db.org/network/224915.bbp_232Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
grpE1 protein networkhttps://string-db.org/network/224915.bbp_233GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleot [...]
yfjF protein networkhttps://string-db.org/network/224915.bbp_234Hypothetical protein; COG2914; Belongs to the UPF0125 (RnfH) family.
smpB protein networkhttps://string-db.org/network/224915.bbp_235SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
yfhC protein networkhttps://string-db.org/network/224915.bbp_236Putative deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
acpS protein networkhttps://string-db.org/network/224915.bbp_237Holo-[acyl-carrier protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
era protein networkhttps://string-db.org/network/224915.bbp_238GTP-binding protein era-like protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and [...]
rnc protein networkhttps://string-db.org/network/224915.bbp_239Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some m [...]
lepB protein networkhttps://string-db.org/network/224915.bbp_240COG0681; SPase I; leader peptidase I; Belongs to the peptidase S26 family.
lepA protein networkhttps://string-db.org/network/224915.bbp_241GTP-Binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codo [...]
trmU protein networkhttps://string-db.org/network/224915.bbp_242Putative tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the for [...]
ycfC protein networkhttps://string-db.org/network/224915.bbp_243Hypothetical protein YcfC; COG2915.
purB protein networkhttps://string-db.org/network/224915.bbp_244Adenylosuccinate lyase; COG0015; adenylosuccinase; ASL.
mltE protein networkhttps://string-db.org/network/224915.bbp_245Membrane-bound lytic murein transglycosylase E; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division (By similarity); Belongs to the t [...]
fabI protein networkhttps://string-db.org/network/224915.bbp_246Enoyl-[acyl-carrier-protein] reductase (NADH); Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in th [...]
rnb protein networkhttps://string-db.org/network/224915.bbp_247Exoribonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity).
ychE protein networkhttps://string-db.org/network/224915.bbp_248Putative membrane protein; COG2095.
lipB protein networkhttps://string-db.org/network/224915.bbp_249Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can al [...]
lipA protein networkhttps://string-db.org/network/224915.bbp_250Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes [...]
pyrF protein networkhttps://string-db.org/network/224915.bbp_251Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamil [...]
ribA protein networkhttps://string-db.org/network/224915.bbp_252GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
cls protein networkhttps://string-db.org/network/224915.bbp_253Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
yciA protein networkhttps://string-db.org/network/224915.bbp_254Putative acyl-CoA thioester hydrolase YciA; COG1607; P14 protein; Belongs to the acyl coenzyme A hydrolase family.
ispZ protein networkhttps://string-db.org/network/224915.bbp_255Putative intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
yciC protein networkhttps://string-db.org/network/224915.bbp_256Hypothetical protein.
trpA protein networkhttps://string-db.org/network/224915.bbp_257Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
trpB protein networkhttps://string-db.org/network/224915.bbp_258Putative tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpC protein networkhttps://string-db.org/network/224915.bbp_259Indole-3-glycerol phosphate synthase; Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the Tr [...]
trpD protein networkhttps://string-db.org/network/224915.bbp_260Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranila [...]
yciL protein networkhttps://string-db.org/network/224915.bbp_262Ribosomal large subunit pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family.
sohB protein networkhttps://string-db.org/network/224915.bbp_263Putative protease SohB; Possible protease; Belongs to the peptidase S49 family.
suhB protein networkhttps://string-db.org/network/224915.bbp_264Myo-inositol-1(or 4)-monophosphatase; COG0483; IMPase; IMP; inositol monophosphatase; lithium-sensitive myo-inositol monophosphatase A1.
yfgB protein networkhttps://string-db.org/network/224915.bbp_265Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proo [...]
hisS protein networkhttps://string-db.org/network/224915.bbp_267histidyl-tRNA synthetase; COG0124; histidine-tRNA ligase; HisRS.
glyA protein networkhttps://string-db.org/network/224915.bbp_268Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
bioD protein networkhttps://string-db.org/network/224915.bbp_269Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ur [...]
bioC protein networkhttps://string-db.org/network/224915.bbp_270Biotin synthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesi [...]
bioF protein networkhttps://string-db.org/network/224915.bbp_2718-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and [...]
bioB protein networkhttps://string-db.org/network/224915.bbp_272Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily [...]
bioA protein networkhttps://string-db.org/network/224915.bbp_273Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8 [...]
ybhE protein networkhttps://string-db.org/network/224915.bbp_274Conserved hypothetical protein; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate.
mfd protein networkhttps://string-db.org/network/224915.bbp_275Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated tr [...]
gapA protein networkhttps://string-db.org/network/224915.bbp_276Glyceraldehyde 3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction [...]
fldA protein networkhttps://string-db.org/network/224915.bbp_277Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
phrB protein networkhttps://string-db.org/network/224915.bbp_278Deoxyribodipyrimidine photolyase; Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn conf [...]
ybgI protein networkhttps://string-db.org/network/224915.bbp_279Conserved hypothetical protein; COG0327.
sucA protein networkhttps://string-db.org/network/224915.bbp_280Oxoglutarate dehydrogenase; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutara [...]
sucB protein networkhttps://string-db.org/network/224915.bbp_281Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conv [...]
pal protein networkhttps://string-db.org/network/224915.bbp_282Peptidoglycan-associated lipoprotein precursor; COG2885; surface antigen; PPL.
gpmA protein networkhttps://string-db.org/network/224915.bbp_283Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
pfkA protein networkhttps://string-db.org/network/224915.bbp_2846-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
tpiA protein networkhttps://string-db.org/network/224915.bbp_285Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
rpsA protein networkhttps://string-db.org/network/224915.bbp_28630S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
cmk protein networkhttps://string-db.org/network/224915.bbp_287Cytidylate kinase; COG0283; CK; cytidine monophosphate kinase; CMP kinase; (MssA protein; P25.
aroA protein networkhttps://string-db.org/network/224915.bbp_2883-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
serC protein networkhttps://string-db.org/network/224915.bbp_289Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belon [...]
serS protein networkhttps://string-db.org/network/224915.bbp_290seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
trxB protein networkhttps://string-db.org/network/224915.bbp_291Thioredoxin reductase; COG0492; TRXR.
infA protein networkhttps://string-db.org/network/224915.bbp_292Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
aspS protein networkhttps://string-db.org/network/224915.bbp_293aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor [...]
znuB protein networkhttps://string-db.org/network/224915.bbp_294High-affinity zinc uptake system membrane protein ZnuB; Involved in the high-affinity zinc uptake transport system. Belongs to the ABC-3 integral membrane protein family.
znuC protein networkhttps://string-db.org/network/224915.bbp_295High-affinity zinc uptake system ATP-binding protein ZnuC; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to [...]
yebA protein networkhttps://string-db.org/network/224915.bbp_296Metalloendopeptidases-like membrane protein; COG0739; Belongs to the peptidase M23B family.
pykA protein networkhttps://string-db.org/network/224915.bbp_297Pyruvate kinase; COG0469; PK; Belongs to the pyruvate kinase family.
zwf protein networkhttps://string-db.org/network/224915.bbp_298Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
htpX protein networkhttps://string-db.org/network/224915.bbp_299Putative protease HtpX; COG0501; heat shock protein HtpX; Belongs to the peptidase M48B family.
yoaE protein networkhttps://string-db.org/network/224915.bbp_300Putative membrane protein; COG1253; COG0861.
yeaZ protein networkhttps://string-db.org/network/224915.bbp_301Putative protease precursor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the tra [...]
minE protein networkhttps://string-db.org/network/224915.bbp_302Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures c [...]
minD protein networkhttps://string-db.org/network/224915.bbp_303Septum site-determining protein; ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking for [...]
minC protein networkhttps://string-db.org/network/224915.bbp_304Putative septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ fila [...]
rsmC protein networkhttps://string-db.org/network/224915.bbp_305Ribosomal RNA small subunit methyltransferase C; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.
mviN protein networkhttps://string-db.org/network/224915.bbp_309Virulence factor MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
flgB protein networkhttps://string-db.org/network/224915.bbp_310Flagellar basal-body rod protein Flgb; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity).
flgC protein networkhttps://string-db.org/network/224915.bbp_311Flagellar basal-body rod protein FlgC; COG1558; putative proximal rod protein; Belongs to the flagella basal body rod proteins family.
flgF protein networkhttps://string-db.org/network/224915.bbp_312Flagellar basal-body rod protein FlgF; COG1749; Belongs to the flagella basal body rod proteins family.
flgG protein networkhttps://string-db.org/network/224915.bbp_313Flagellar basal-body rod protein FlgG; COG1749; distal rod protein; Belongs to the flagella basal body rod proteins family.
flgH protein networkhttps://string-db.org/network/224915.bbp_314Flagellar L-ring protein precursor; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
flgI protein networkhttps://string-db.org/network/224915.bbp_315Flagellar P-ring protein precursor; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
flgJ protein networkhttps://string-db.org/network/224915.bbp_316Flagellar protein FlgJ-like protein; COG1705.
rne protein networkhttps://string-db.org/network/224915.bbp_317Ribonuclease G; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation [...]
rluC protein networkhttps://string-db.org/network/224915.bbp_318Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA; Belongs to the pseudouridine synthas [...]
rpmF protein networkhttps://string-db.org/network/224915.bbp_31950S ribosomal protein L32; COG0333; Belongs to the bacterial ribosomal protein bL32 family.
fabD protein networkhttps://string-db.org/network/224915.bbp_320Malonyl CoA-acyl carrier protein transacylase; COG0331; MCT; Belongs to the FabD family.
fabG protein networkhttps://string-db.org/network/224915.bbp_3213-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cy [...]
acpP protein networkhttps://string-db.org/network/224915.bbp_322Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
tmk protein networkhttps://string-db.org/network/224915.bbp_323Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
holB protein networkhttps://string-db.org/network/224915.bbp_324DNA polymerase III delta' subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exo [...]
ycfH protein networkhttps://string-db.org/network/224915.bbp_325Putative deoxyribonuclease; COG0084.
ptsG protein networkhttps://string-db.org/network/224915.bbp_326PTS system glucose-specific IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylat [...]
ycfF protein networkhttps://string-db.org/network/224915.bbp_327Hypothetical HIT-like protein; COG0537.
asnS protein networkhttps://string-db.org/network/224915.bbp_329asparaginyl-tRNA synthetase; COG0017; asparagine-tRNA ligase; ASNRS.
yceA protein networkhttps://string-db.org/network/224915.bbp_330Conserved hypothetical protein; COG1054; Belongs to the UPF0176 family.
valS protein networkhttps://string-db.org/network/224915.bbp_331valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
pepA protein networkhttps://string-db.org/network/224915.bbp_332Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
argF protein networkhttps://string-db.org/network/224915.bbp_333Ornithine carbamoyltransferase anabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; [...]
yhaR protein networkhttps://string-db.org/network/224915.bbp_334Translational inhibitor protein; COG0251; p14.5; UK114 antigen homolog; Belongs to the RutC family.
deaD protein networkhttps://string-db.org/network/224915.bbp_335ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
pnp protein networkhttps://string-db.org/network/224915.bbp_336Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
rpsO protein networkhttps://string-db.org/network/224915.bbp_33730S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging seve [...]
truB protein networkhttps://string-db.org/network/224915.bbp_338tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
rbfA protein networkhttps://string-db.org/network/224915.bbp_339Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
infB protein networkhttps://string-db.org/network/224915.bbp_340Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
nusA protein networkhttps://string-db.org/network/224915.bbp_341N utilization substance protein A; Participates in both transcription termination and antitermination.
mrsA protein networkhttps://string-db.org/network/224915.bbp_344Putative phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
hflB protein networkhttps://string-db.org/network/224915.bbp_345Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In [...]
ftsJ protein networkhttps://string-db.org/network/224915.bbp_346Ribosomal RNA large subunit methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
greA protein networkhttps://string-db.org/network/224915.bbp_347Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...]
yrbA protein networkhttps://string-db.org/network/224915.bbp_348YrbA; COG0271; Belongs to the BolA/IbaG family.
murA protein networkhttps://string-db.org/network/224915.bbp_349UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
rplU protein networkhttps://string-db.org/network/224915.bbp_35050S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
rpmA protein networkhttps://string-db.org/network/224915.bbp_35150S ribosomal protein L27; COG0211; BL30; BL24; Belongs to the bacterial ribosomal protein bL27 family.
yhbZ protein networkhttps://string-db.org/network/224915.bbp_352GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role [...]
rpsI protein networkhttps://string-db.org/network/224915.bbp_353Ribosomal protein S9; COG0103; BS10; Belongs to the universal ribosomal protein uS9 family.
rplM protein networkhttps://string-db.org/network/224915.bbp_35450S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages [...]
pheA protein networkhttps://string-db.org/network/224915.bbp_355P-protein; Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
ffh protein networkhttps://string-db.org/network/224915.bbp_356Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nasce [...]
rpsP protein networkhttps://string-db.org/network/224915.bbp_35730S ribosomal protein S16; COG0228; BS17; Belongs to the bacterial ribosomal protein bS16 family.
rimM protein networkhttps://string-db.org/network/224915.bbp_35816S rRNA processing protein rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19 [...]
trmD protein networkhttps://string-db.org/network/224915.bbp_359tRNA (Guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rplS protein networkhttps://string-db.org/network/224915.bbp_36050S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
tldD protein networkhttps://string-db.org/network/224915.bbp_361TldD protein; Probable metalloprotease.
aroQ protein networkhttps://string-db.org/network/224915.bbp_3623-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
rluD protein networkhttps://string-db.org/network/224915.bbp_363Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; Belongs to the pseudouridine syntha [...]
alaS protein networkhttps://string-db.org/network/224915.bbp_364alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
csrA protein networkhttps://string-db.org/network/224915.bbp_365Carbon storage regulator-like protein; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting [...]
gshA protein networkhttps://string-db.org/network/224915.bbp_368Glutamate-cysteine ligase; COG2918; gamma-glutamylcysteine synthetase; gamma-ECS; GCS; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
endA protein networkhttps://string-db.org/network/224915.bbp_369Endonuclease I; Has double-strand break activity; Belongs to the EndA/NucM nuclease family.
ygfA protein networkhttps://string-db.org/network/224915.bbp_3705-formyltetrahydrofolate cyclo-ligase; COG0212; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
rpiA protein networkhttps://string-db.org/network/224915.bbp_371Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
glnS protein networkhttps://string-db.org/network/224915.bbp_375glutaminyl-tRNA synthetase; COG0008; glutamine-tRNA ligase; GLNRS.
pyrG protein networkhttps://string-db.org/network/224915.bbp_376CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the fo [...]
eno protein networkhttps://string-db.org/network/224915.bbp_377Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
mutS protein networkhttps://string-db.org/network/224915.bbp_380DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase act [...]
dsbA protein networkhttps://string-db.org/network/224915.bbp_381Thiol:disulfide interchange protein DsbA precursor; Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins (By similarity).
polA protein networkhttps://string-db.org/network/224915.bbp_382Putative 5'-3' exonuclease; 5'-3' exonuclease acting preferentially on double-stranded DNA.
engB protein networkhttps://string-db.org/network/224915.bbp_383Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. E [...]
typA protein networkhttps://string-db.org/network/224915.bbp_384GTP-binding protein TYPA/BIPA; A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP [...]
gmk protein networkhttps://string-db.org/network/224915.bbp_385Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
thyA protein networkhttps://string-db.org/network/224915.bbp_386Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate ( [...]
lgt protein networkhttps://string-db.org/network/224915.bbp_387Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
lysA protein networkhttps://string-db.org/network/224915.bbp_388Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
lysS protein networkhttps://string-db.org/network/224915.bbp_389lysyl-tRNA synthetase; COG1190; lysine-tRNA ligase; LYSRS; Belongs to the class-II aminoacyl-tRNA synthetase family.
prfB protein networkhttps://string-db.org/network/224915.bbp_390Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
ygfZ protein networkhttps://string-db.org/network/224915.bbp_391Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that [...]
yleA protein networkhttps://string-db.org/network/224915.bbp_392Hypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in t [...]
ybeY protein networkhttps://string-db.org/network/224915.bbp_393Hypothetical protein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
corC protein networkhttps://string-db.org/network/224915.bbp_394Magnesium and cobalt efflux protein CorC; Plays a role in the transport of magnesium and cobalt ions.
leuS protein networkhttps://string-db.org/network/224915.bbp_395leucyl-tRNA synthetase; COG0495; leucine-tRNA ligase; LEURS; Belongs to the class-I aminoacyl-tRNA synthetase family.
holA protein networkhttps://string-db.org/network/224915.bbp_396DNA polymerase III delta subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exon [...]
sirA protein networkhttps://string-db.org/network/224915.bbp_397SirA protein; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble b [...]
asd protein networkhttps://string-db.org/network/224915.bbp_398Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the as [...]
yhgN protein networkhttps://string-db.org/network/224915.bbp_399Putative membrane protein; COG2095.
pgk protein networkhttps://string-db.org/network/224915.bbp_400Phosphoglycerate kinase; COG0126; Belongs to the phosphoglycerate kinase family.
fba protein networkhttps://string-db.org/network/224915.bbp_401Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bi [...]
yggB protein networkhttps://string-db.org/network/224915.bbp_402Putative membrane protein; COG0668.
recC protein networkhttps://string-db.org/network/224915.bbp_403Exodeoxyribonuclease V gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-depend [...]
recB protein networkhttps://string-db.org/network/224915.bbp_404Exodeoxyribonuclease V beta chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-depende [...]
recD protein networkhttps://string-db.org/network/224915.bbp_405Exodeoxyribonuclease V alpha chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-depend [...]
ribH protein networkhttps://string-db.org/network/224915.bbp_4076,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. [...]
ribD protein networkhttps://string-db.org/network/224915.bbp_408Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphat [...]
nusB protein networkhttps://string-db.org/network/224915.bbp_409N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of t [...]
yajR protein networkhttps://string-db.org/network/224915.bbp_411Putative transport protein; COG0477.
yccK protein networkhttps://string-db.org/network/224915.bbp_412Putative sulfite reductase subunit protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulf [...]
cyoE protein networkhttps://string-db.org/network/224915.bbp_413Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
cyoD protein networkhttps://string-db.org/network/224915.bbp_414Cytochrome O ubiquinol oxidase protein CyoD; Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high [...]
cyoC protein networkhttps://string-db.org/network/224915.bbp_415Cytochrome O ubiquinol oxidase subunit III; Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high [...]
cyoB protein networkhttps://string-db.org/network/224915.bbp_416Ubiquinol oxidase polypeptide I; Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. H [...]
cyoA protein networkhttps://string-db.org/network/224915.bbp_417Ubiquinol oxidase polypeptide II precursor; Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high [...]
bolA protein networkhttps://string-db.org/network/224915.bbp_418BolA; COG0271; Belongs to the BolA/IbaG family.
clpP protein networkhttps://string-db.org/network/224915.bbp_419ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degrada [...]
clpX protein networkhttps://string-db.org/network/224915.bbp_420Putative ATP-dependent protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
lon protein networkhttps://string-db.org/network/224915.bbp_421ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for [...]
ppiD protein networkhttps://string-db.org/network/224915.bbp_422Peptidyl-prolyl cis-trans isomerase D; PPIases accelerate the folding of proteins.
mdlA protein networkhttps://string-db.org/network/224915.bbp_423Putative ABC transporter; COG1132; ATP-binding protein; Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
mdlB protein networkhttps://string-db.org/network/224915.bbp_424Putative ATP transporter; COG1132; ATP-binding protein; Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
dnaX protein networkhttps://string-db.org/network/224915.bbp_425DNA polymerase III subunit gamma; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exon [...]
ybaB protein networkhttps://string-db.org/network/224915.bbp_426Hypothetical protein YbaB; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
htpG protein networkhttps://string-db.org/network/224915.bbp_427Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
adk protein networkhttps://string-db.org/network/224915.bbp_428Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
folD protein networkhttps://string-db.org/network/224915.bbp_430Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10 [...]
cysS protein networkhttps://string-db.org/network/224915.bbp_431cysteinyl-tRNA synthetase; COG0215; cysteine-tRNA ligase; CysRS; Belongs to the class-I aminoacyl-tRNA synthetase family.
ybeD protein networkhttps://string-db.org/network/224915.bbp_432Hypothetical protein YbeD; COG2921; Belongs to the UPF0250 family.
cspE protein networkhttps://string-db.org/network/224915.bbp_433COG1278; CSP-A; cold shock protein; CS7.4.
aroE protein networkhttps://string-db.org/network/224915.bbp_437Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshi [...]
yrdC protein networkhttps://string-db.org/network/224915.bbp_438Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conve [...]
def protein networkhttps://string-db.org/network/224915.bbp_439Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine i [...]
fmt protein networkhttps://string-db.org/network/224915.bbp_440methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
rplQ protein networkhttps://string-db.org/network/224915.bbp_44150S ribosomal protein L17; COG0203.
rpoA protein networkhttps://string-db.org/network/224915.bbp_442DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpsD protein networkhttps://string-db.org/network/224915.bbp_443Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpsK protein networkhttps://string-db.org/network/224915.bbp_44430S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
rpsM protein networkhttps://string-db.org/network/224915.bbp_44530S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 [...]
rpmJ protein networkhttps://string-db.org/network/224915.bbp_446COG0257; ribosomal protein II; ribosomal protein B; BL38; Belongs to the bacterial ribosomal protein bL36 family.
secY protein networkhttps://string-db.org/network/224915.bbp_447Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at t [...]
rplO protein networkhttps://string-db.org/network/224915.bbp_44850S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
rpmD protein networkhttps://string-db.org/network/224915.bbp_44950S ribosomal protein L30; COG1841.
rpsE protein networkhttps://string-db.org/network/224915.bbp_45030S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
rplR protein networkhttps://string-db.org/network/224915.bbp_45150S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protubera [...]
rplF protein networkhttps://string-db.org/network/224915.bbp_45250S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the t [...]
rpsH protein networkhttps://string-db.org/network/224915.bbp_45330S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to [...]
rpsN protein networkhttps://string-db.org/network/224915.bbp_45430S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the un [...]
rplE protein networkhttps://string-db.org/network/224915.bbp_45550S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [...]
rplX protein networkhttps://string-db.org/network/224915.bbp_456Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rplN protein networkhttps://string-db.org/network/224915.bbp_45750S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rpsQ protein networkhttps://string-db.org/network/224915.bbp_45830S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rpmC protein networkhttps://string-db.org/network/224915.bbp_45950S ribosomal protein L29; COG0255; Belongs to the universal ribosomal protein uL29 family.
rplP protein networkhttps://string-db.org/network/224915.bbp_46050S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpsC protein networkhttps://string-db.org/network/224915.bbp_46130S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplV protein networkhttps://string-db.org/network/224915.bbp_46250S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50 [...]
rpsS protein networkhttps://string-db.org/network/224915.bbp_463S19 ribosomal protein; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplB protein networkhttps://string-db.org/network/224915.bbp_46450S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rplW protein networkhttps://string-db.org/network/224915.bbp_46550S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main dock [...]
rplD protein networkhttps://string-db.org/network/224915.bbp_46650S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes [...]
rplC protein networkhttps://string-db.org/network/224915.bbp_46750S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rpsJ protein networkhttps://string-db.org/network/224915.bbp_46830S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
tuf protein networkhttps://string-db.org/network/224915.bbp_469Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
fusA protein networkhttps://string-db.org/network/224915.bbp_470Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- [...]
rpsG protein networkhttps://string-db.org/network/224915.bbp_47130S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit inte [...]
rpsL protein networkhttps://string-db.org/network/224915.bbp_47230S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
yheL protein networkhttps://string-db.org/network/224915.bbp_473Hypothetical protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
yheM protein networkhttps://string-db.org/network/224915.bbp_474Conserved hypothetical protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
yheN protein networkhttps://string-db.org/network/224915.bbp_475Conserved hypothetical protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and [...]
fkpA protein networkhttps://string-db.org/network/224915.bbp_476FKBP-type peptidyl-prolyl cis-trans isomerase FkpA; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs [...]
yhfC protein networkhttps://string-db.org/network/224915.bbp_477Putative transport; COG0477.
trpS protein networkhttps://string-db.org/network/224915.bbp_478tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
rpe protein networkhttps://string-db.org/network/224915.bbp_479Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
aroB protein networkhttps://string-db.org/network/224915.bbp_4803-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquin [...]
aroK protein networkhttps://string-db.org/network/224915.bbp_481Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
deoD protein networkhttps://string-db.org/network/224915.bbp_483Purine nucleoside phosphorylase; COG0813; inosine phosphorylase; PNP.
deoB protein networkhttps://string-db.org/network/224915.bbp_484Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
prfC protein networkhttps://string-db.org/network/224915.bbp_485Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for U [...]
yhgI protein networkhttps://string-db.org/network/224915.bbp_486YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a [...]
bioH protein networkhttps://string-db.org/network/224915.bbp_487Putative biotin biosynthesis protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP vi [...]
ssb protein networkhttps://string-db.org/network/224915.bbp_488Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action du [...]
dnaB protein networkhttps://string-db.org/network/224915.bbp_489Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DN [...]
gshB protein networkhttps://string-db.org/network/224915.bbp_490COG0189; glutathione synthase; GSH synthetase; GSH-S; GSHASE.
yqgE protein networkhttps://string-db.org/network/224915.bbp_491Conserved hypothetical protein; COG1678; Belongs to the UPF0301 (AlgH) family.
yqgF protein networkhttps://string-db.org/network/224915.bbp_492Hypothetical 16.0 kDa protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.
leuA protein networkhttps://string-db.org/network/224915.bbp_4932-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isoprop [...]
leuD protein networkhttps://string-db.org/network/224915.bbp_4943-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. Leu [...]
leuC protein networkhttps://string-db.org/network/224915.bbp_4953-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
leuB protein networkhttps://string-db.org/network/224915.bbp_4963-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-met [...]
yggS protein networkhttps://string-db.org/network/224915.bbp_497Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
yggW protein networkhttps://string-db.org/network/224915.bbp_498Putative oxidase; Might be a heme chaperone; in E.coli heme binds independently of binding to [4Fe-4S] or S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. [...]
yggH protein networkhttps://string-db.org/network/224915.bbp_499Hypothetical methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
mutY protein networkhttps://string-db.org/network/224915.bbp_500A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine [...]
yggX protein networkhttps://string-db.org/network/224915.bbp_501Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic en [...]
murI protein networkhttps://string-db.org/network/224915.bbp_502Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
sbcB protein networkhttps://string-db.org/network/224915.bbp_503Exodeoxyribonuclease I; Degrades single-stranded DNA (ssDNA) in a highly processive manner. Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties followi [...]
pyrE protein networkhttps://string-db.org/network/224915.bbp_506Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
dut protein networkhttps://string-db.org/network/224915.bbp_507Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intrace [...]
rplI protein networkhttps://string-db.org/network/224915.bbp_50850S ribosomal protein L9; Binds to the 23S rRNA.
rpsR protein networkhttps://string-db.org/network/224915.bbp_50930S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosom [...]
rpsF protein networkhttps://string-db.org/network/224915.bbp_51030S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
purA protein networkhttps://string-db.org/network/224915.bbp_511Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
hflC protein networkhttps://string-db.org/network/224915.bbp_512HflC; HflC and HflK could regulate a protease.
hflK protein networkhttps://string-db.org/network/224915.bbp_513HflK; HflC and HflK could encode or regulate a protease.
miaA protein networkhttps://string-db.org/network/224915.bbp_514tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to th [...]
mutL protein networkhttps://string-db.org/network/224915.bbp_515DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchm [...]
mtlD protein networkhttps://string-db.org/network/224915.bbp_516Mannitol-1-phosphate dehydrogenase; COG0246.
mtlA protein networkhttps://string-db.org/network/224915.bbp_517PTS system mannitol-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphoryl [...]
pgi protein networkhttps://string-db.org/network/224915.bbp_518COG0166; GPI; phosphoglucose isomerase; PGI; phosphohexose isomerase; PHI.
orn protein networkhttps://string-db.org/network/224915.bbp_519Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
amiB protein networkhttps://string-db.org/network/224915.bbp_521Putative N-acetylmuramoyl-L-alanine amidase; Cell-wall hydrolase involved in septum cleavage during cell division.
rpmE protein networkhttps://string-db.org/network/224915.bbp_52250S ribosomal protein L31; Binds the 23S rRNA.
hslV protein networkhttps://string-db.org/network/224915.bbp_523ATP-dependent protease HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
hslU protein networkhttps://string-db.org/network/224915.bbp_524ATP-dependent hsl protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis [...]
trpG protein networkhttps://string-db.org/network/224915.bbp_525Anthranilate synthase component II; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first [...]
trpE protein networkhttps://string-db.org/network/224915.bbp_526Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first [...]
fpr protein networkhttps://string-db.org/network/224915.bbp_527ferredoxin-NADP reductase; Transports electrons between flavodoxin or ferredoxin and NADPH.
yjeA protein networkhttps://string-db.org/network/224915.bbp_528Putative lysyl-tRNA synthetase; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-dependent ac [...]
uspA protein networkhttps://string-db.org/network/224915.bbp_530Universal stress protein; Required for resistance to DNA-damaging agents.
pitA protein networkhttps://string-db.org/network/224915.bbp_531Putative phosphate transporter; Low-affinity inorganic phosphate transport; Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
ynfM protein networkhttps://string-db.org/network/224915.bbp_532Putative transport protein; COG0477.
dapF protein networkhttps://string-db.org/network/224915.bbp_533Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...]
cyaY protein networkhttps://string-db.org/network/224915.bbp_534CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
rho protein networkhttps://string-db.org/network/224915.bbp_538Rranscription termination factor rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
trxA protein networkhttps://string-db.org/network/224915.bbp_539Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
rep protein networkhttps://string-db.org/network/224915.bbp_540ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded [...]
ilvC protein networkhttps://string-db.org/network/224915.bbp_541Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yie [...]
ilvD protein networkhttps://string-db.org/network/224915.bbp_542Dihydroxy-acid dehydratase; COG0129; DAD; Belongs to the IlvD/Edd family.
nifS protein networkhttps://string-db.org/network/224915.bbp_544Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental [...]
iscU protein networkhttps://string-db.org/network/224915.bbp_545Putative NifU; A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the role of t [...]
hscB protein networkhttps://string-db.org/network/224915.bbp_546Chaperone protein HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
hscA protein networkhttps://string-db.org/network/224915.bbp_547Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the [...]
fdx protein networkhttps://string-db.org/network/224915.bbp_548Ferredoxin; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions; Belongs to the adrenodoxin/putidaredoxin family.
engA protein networkhttps://string-db.org/network/224915.bbp_549Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (De [...]
yfgM protein networkhttps://string-db.org/network/224915.bbp_550Hypothetical protein.