Organism Overview: Mycobacterium leprae


 
dnaA protein networkhttps://string-db.org/network/272631.gene:17573810Putative chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically [...]
dnaN protein networkhttps://string-db.org/network/272631.gene:17573811Putative DNA polymerase III, [beta] subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the [...]
recF protein networkhttps://string-db.org/network/272631.gene:17573812Putative DNA replication and SOS induction protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to si [...]
ML0004 protein networkhttps://string-db.org/network/272631.gene:17573813Similar to hypothetical proteins from mycobacteria e.g. M. tuberculosis Rv0004, ypothetical protein, TR:P71573 (EMBL:AL123456) (187 aa); Fasta score E(): 0, 77.2% identity in 167 aa overlap. Prev [...]
gyrB protein networkhttps://string-db.org/network/272631.gene:17573814Putative DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromos [...]
gyrA protein networkhttps://string-db.org/network/272631.gene:17573815Putative DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromos [...]
ML0007 protein networkhttps://string-db.org/network/272631.gene:17573816Putative membrane protein; Similar to M. tuberculosis Rv0007, hypothetical protein, TR:P71575 (EMBL:AL123456) (304 aa); Fasta score E(): 0, 53.8% identity in 316 aa overlap. Previously sequenced [...]
ML0008 protein networkhttps://string-db.org/network/272631.gene:17573819Hypothetical protein; Unknown function.
ppiA protein networkhttps://string-db.org/network/272631.gene:17573822Putative peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity) [...]
ML0012 protein networkhttps://string-db.org/network/272631.gene:17573823Putative membrane protein; Similar to M. tuberculosis Rv0010c, hypothetical protein, SW:Y010_MYCTU (P71580) (141 aa); Fasta score E(): 0, 71.5% identity in 137 aa overlap. Contains hydrophobic, p [...]
ML0013 protein networkhttps://string-db.org/network/272631.gene:17573824Conserved hypothetical protein; Involved in cell division; Belongs to the CrgA family.
pabA protein networkhttps://string-db.org/network/272631.gene:17573826EC_number=4.1.3.-; Similar to M. tuberculosis pabA, p-aminobenzoate synthase glutamine amidotransferase, TR:Q50183 (EMBL:Z70722) (232 aa); Fasta score E(): 0, 100.0% identity in 232 aa overlap (E [...]
pknB protein networkhttps://string-db.org/network/272631.gene:17573827Putative serine/threonine protein kinase; Protein kinase that regulates many aspects of mycobacterial physiology. Is a key component of a signal transduction pathway that regulates cell growth, c [...]
pknA protein networkhttps://string-db.org/network/272631.gene:17573828Putative serine/threonine protein kinase; Protein kinase that regulates many aspects of mycobacterial physiology. Is a key component of a signal transduction pathway that regulates cell growth, c [...]
pbpA protein networkhttps://string-db.org/network/272631.gene:17573829Similar to M. tuberculosis pbpA, penicillin-binding protein, TR:P71586 (EMBL:AL123456) (491 aa); Fasta score E(): 0, 85.7% identity in 490 aa overlap. Also similar to Bacillus subtilis penicillin [...]
rodA protein networkhttps://string-db.org/network/272631.gene:17573830Similar to M. tuberculosis ftsW, cell-division protein, SW:FTSW_MYCTU (P71587) (469 aa); Fasta score E(): 0, 82.3% identity in 469 aa overlap and to Streptomyces coelicolor ftsW, cell-division pr [...]
ML0020 protein networkhttps://string-db.org/network/272631.gene:17573831Conserved hypothetical protein; Similar to M. tuberculosis ppp, putative protein phosphatase, TR:P71588 (EMBL:AL123456) (514 aa); Fasta score E(): 0, 76.4% identity in 513 aa overlap and to Strep [...]
ML0021 protein networkhttps://string-db.org/network/272631.gene:17573832Similar to M. tuberculosis Rv0019c, hypothetical protein, TR:P71589 and to Streptomyces coelicolor SCH69.14, hypothetical protein, TR:Q9XA20 (EMBL:AL079308) (172 aa); Fasta score E(): 2e-21, 44.4 [...]
ML0022 protein networkhttps://string-db.org/network/272631.gene:17573833Similar to M. tuberculosis Rv0020c, hypothetical protein, TR:P71590 (EMBL:AL123456) (527 aa); Fasta score E(): 0, 71.9% identity in 531 aa overlap. Previously sequenced as TR:Q50190 (EMBL:Z70722) [...]
ML0023 protein networkhttps://string-db.org/network/272631.gene:17573835Hypothetical protein; Improbable CDS, possibly the remains of a disrupted gene.
ML0028 protein networkhttps://string-db.org/network/272631.gene:17573840Similar to M. tuberculosis Rv0038, hypothetical protein, TR:P71608 (EMBL:AL123456) (202 aa); Fasta score E(): 0, 88.1% identity in 202 aa overlap. Similar to Streptomyces coelicolor SCE59.07C, hy [...]
ML0029 protein networkhttps://string-db.org/network/272631.gene:17573841Possible membrane protein; Contains a region similar to part of several bacterial hypothetical membrane proteins e.g. Streptomyces coelicolor SC4B5.06, putative transmembrane protein, TR:Q9ZBW2 ( [...]
ML0030 protein networkhttps://string-db.org/network/272631.gene:17573842Putative membrane protein; Similar to M. tuberculosis Rv0039c, hypothetical protein, TR:P71696 (EMBL:AL123456) (115 aa); Fasta score E(): 2.2e-25, 63.2% identity in 114 aa overlap. Previously seq [...]
ML0031 protein networkhttps://string-db.org/network/272631.gene:17573843Similar to M. tuberculosis MTC28, Rv0040c, proline rich 28 KDa antigen precursoR, SW:PR28_MYCTU (P71697) (311 aa); Fasta score E(): 0, 65.1% identity in 258 aa overlap. Previously sequenced as TR [...]
leuS protein networkhttps://string-db.org/network/272631.gene:17573844leucyl-tRNA synthase; Similar to M. tuberculosis leuS, leucyl-tRNA synthetase, SW:SYL_MYCTU (P71698) (969 aa); Fasta score E(): 0, 83.6% identity in 972 aa overlap and to Bacillus subtilis leuS, [...]
ML0041 protein networkhttps://string-db.org/network/272631.gene:17573853Probable secreted protease; Similar to M. tuberculosis putative proteases e.g. Rv3883c, probable secreted protease, TR:O05461 (EMBL:AL123456) (446 aa); Fasta score E(): 0, 79.1% identity in 446 a [...]
ML0042 protein networkhttps://string-db.org/network/272631.gene:17573854Putative membrane protein; Similar to M. tuberculosis Rv3882c, conserved hypothetical protein, TR:O05462 (EMBL:AL123456) (462 aa); Fasta score E(): 0, 72.1% identity in 462 aa overlap. Shows weak [...]
ML0044 protein networkhttps://string-db.org/network/272631.gene:17573856Conserved hypothetical protein (pseudogene); Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the Y [...]
ML0047 protein networkhttps://string-db.org/network/272631.gene:17573859Similar to M. tuberculosis putative membrane protein e.g. Rv3877, hypothetical protein, TR:O69741 (EMBL:AL123456) (511 aa); Fasta score E(): 0, 74.0% identity in 512 aa overlap. Similarity is wea [...]
ML0048 protein networkhttps://string-db.org/network/272631.gene:17573860Conserved hypothetical protein; Has a proline-rich N-terminus. Similar to several proteins from M. tuberculosis, some of which also contain proline-rich regions e.g. M.tuberculosis Rv3876, hypoth [...]
ML0049 protein networkhttps://string-db.org/network/272631.gene:17573861Possible secreted protein; A secreted protein that might play a role in virulence.
ML0050 protein networkhttps://string-db.org/network/272631.gene:17573862Possible secreted protein; A secreted protein that might play a role in virulence. Might serve as a chaperone to prevent uncontrolled membrane lysis by its partner EsxA.
ML0051 protein networkhttps://string-db.org/network/272631.gene:17573863Similar to PPE-family proteins from M. tuberculosis e.g. Rv3873, PPE-family protein, TR:O69738 (EMBL:AL123456) (368 aa); Fasta score E(): 6.1e-32, 46.2% identity in 288 aa overlap. Lacks the PPE [...]
ML0052 protein networkhttps://string-db.org/network/272631.gene:17573864Conserved hypothetical protein; Similar to putative ATP/GTP-binding proteins from M. tuberculosis and Streptomyces coelicolor e.g. M. tuberculosis Rv3871, hypothetical protein, TR:O69736 (EMBL:AL [...]
ML0053 protein networkhttps://string-db.org/network/272631.gene:17573865Similar to putative ATP/GTP-binding proteins from M. tuberculosis and Streptomyces coelicolor e.g. M. tuberculosis Rv3870, hypothetical protein, TR:O69735 (EMBL:AL123456) (747 aa); Fasta score E( [...]
ML0054 protein networkhttps://string-db.org/network/272631.gene:17573866Putative membrane protein; Similar to several M. tuberculosis hypothetical proteins e.g. Rv3869, conserved hypothetical protein, TR:O69734 (EMBL:AL123456) (480 aa); Fasta score E(): 0, 75.7% iden [...]
ML0055 protein networkhttps://string-db.org/network/272631.gene:17573867Conserved hypothetical protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. EccA1 exhibits ATPase activity and may pr [...]
ML0056 protein networkhttps://string-db.org/network/272631.gene:17573868Similar to M. tuberculosis Rv3867, conserved hypothetical protein, TR:O06269 (EMBL:AL123456) (184 aa); Fasta score E(): 1.1e-12, 38.4% identity in 172 aa overlap and to Rv3614c, hypothetical prot [...]
gltB protein networkhttps://string-db.org/network/272631.gene:17573873Similar to M. tuberculosis Rv3859c, putative ferredoxin-dependent glutamate synthase, TR:P96218 (EMBL:Al123456) (1527 aa); Fasta score E(): 0, 90.2% identity in 1527 aa overlap and to Synechocyst [...]
gltD protein networkhttps://string-db.org/network/272631.gene:17573874Similar to M. tuberculosis Rv3858c, gltD, putative NADH-dependent glutamate synthase small subunit, TR:P96219 (EMBL:Al123456) (488 aa); Fasta score E(): 0, 87.7% identity in 488 aa overlap and to [...]
ML0064 protein networkhttps://string-db.org/network/272631.gene:17573876Similar to M. tuberculosis Rv3855, putative transcriptional regulator, TR:P96222 (EMBL:Al123456) (216 aa); Fasta score E(): 0, 77.0% identity in 213 aa overlap. Contains a probable helix-turn-hel [...]
ML0065 protein networkhttps://string-db.org/network/272631.gene:17573877Similar to putative monooxygenases from M. tuberculosis e.g. Rv3854c, probable monooxygenase, TR:P96223 (EMBL:AL123456) (489 aa); Fasta score E(): 0, 80.1% identity in 488 aa overlap. Others are [...]
menG protein networkhttps://string-db.org/network/272631.gene:17573878Putative S-adenosylmethionine:2-demethylmenaquinone methyltransferase; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secon [...]
hns protein networkhttps://string-db.org/network/272631.gene:17573879Histone-like protein; Similar to M. tuberculosis Rv3852, hns, HU-histone protein, TR:P96225 (EMBL:AL123456) (134 aa); Fasta score E(): 6.1e-12, 51.5% identity in 134 aa overlap. Contains PAKKX re [...]
ML0068 protein networkhttps://string-db.org/network/272631.gene:17573880Similar to M. tuberculosis Rv3850, hypothetical protein, TR:P96227 (EMBL:AL123456) (218 aa); Fasta score E(): 0, 78.3% identity in 217 aa overlap.
ML0069 protein networkhttps://string-db.org/network/272631.gene:17573881Similar to M. tuberculosis Rv3849, hypothetical protein, TR:P96228 (EMBL:AL123456) (132 aa); Fasta score E(): 0, 84.0% identity in 131 aa overlap.
ML0071 protein networkhttps://string-db.org/network/272631.gene:17573883Similar to M. tuberculosis Rv3847, hypothetical protein, TR:P96230 (EMBL:AL123456) (177 aa); Fasta score E(): 0, 96.6% identity in 177 aa overlap.
sodA protein networkhttps://string-db.org/network/272631.gene:17573884Superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
ML0073 protein networkhttps://string-db.org/network/272631.gene:17573885Putative membrane protein; Similar to M. tuberculosis Rv3843c, putative membrane protein, TR:P96235 (EMBL:Z83864) (342 aa); Fasta score E(): 0, 63.0% identity in 349 aa overlap. Contains hydropho [...]
glpQ protein networkhttps://string-db.org/network/272631.gene:17573886Similar to M. tuberculosis Rv3842c, glpQ1, glycerophosphoryl diester phosphodiesterase, TR:P96236 (EMBL:AL123456) (274 aa); Fasta score E(): 0, 88.8% identity in 269 aa overlap. Similar to Bacill [...]
pheA protein networkhttps://string-db.org/network/272631.gene:17573890Putative prephenate dehydratase; Similar to M. tuberculosis Rv3838c, pheA, prephenate dehydratase, TR:P96240 (EMBL:AL123456) (321 aa); Fasta score E(): 0, 83.9% identity in 311 aa overlap. Simila [...]
ML0079 protein networkhttps://string-db.org/network/272631.gene:17573891Similar to M. tuberculosis Rv3837c, putative phosphoglycerate mutase, TR:P96241 (EMBL:AL123456) (232 aa); Fasta score E(): 0, 71.6% identity in 232 aa overlap. Similar to Amycolatopsis methanolic [...]
ML0081 protein networkhttps://string-db.org/network/272631.gene:17573893Putative membrane protein; Similar to M. tuberculosis Rv3835c, hypothetical protein, TR:P96243 (EMBL:AL123456) (449 aa); Fasta score E(): 0, 69.4% identity in 457 aa overlap. Contains hydrophobic [...]
serS protein networkhttps://string-db.org/network/272631.gene:17573894Putative seryl-tRNA synthase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be f [...]
ML0087 protein networkhttps://string-db.org/network/272631.gene:17573899Putative acyltransferase; Similar to M. tuberculosis Rv3816c, probable acyltransferase, TR:O07807 (EMBL:AL123456) (259 aa); Fasta score E(): 0, 81.5% identity in 254 aa overlap. Also similar to t [...]
ML0091 protein networkhttps://string-db.org/network/272631.gene:1757390328 KDa antigen precursor; Similar to M. tuberculosis Rv3810, erp, pirG, exported repetitive protein precursor, SW:ERP_MYCTU (Q50793) (284 aa); Fasta score E(): 1.8e-23, 52.7% identity in 281 aa o [...]
glf protein networkhttps://string-db.org/network/272631.gene:17573904Similar to M. tuberculosis Rv3809c, glf, UDP-galactopyranose mutase, TR:O06934 (EMBL:U96128) (399 aa); Fasta score E(): 0, 86.6% identity in 396 aa overlap. Similar to e.g. Escherichia coli glf, [...]
ML0093 protein networkhttps://string-db.org/network/272631.gene:17573905Similar to M. tuberculosis Rv3808c, hypothetical protein, TR:O53585 (EMBL:AL123456) (637 aa); Fasta score E(): 0, 85.4% identity in 643 aa overlap.
ML0094 protein networkhttps://string-db.org/network/272631.gene:17573906Putative membrane protein; Similar to M. tuberculosis Rv3807c, possible membrane protein, TR:O53584 (EMBL:AL123456) (165 aa); Fasta score E(): 0, 72.8% identity in 151 aa overlap and to Streptomy [...]
ML0095 protein networkhttps://string-db.org/network/272631.gene:17573907Similar to M. tuberculosis Rv3806c, possible integral membrane protein, TR:O53583 (EMBL:AL123456) (302 aa); Fasta score E(): 0, 83.8% identity in 302 aa overlap and to bacterial putative membrane [...]
ML0096 protein networkhttps://string-db.org/network/272631.gene:17573908Putative membrane protein; Similar to M. tuberculosis Rv3805c, possible membrane protein, TR:O53582 (EMBL:AL123456) (627 aa); Fasta score E(): 0, 80.9% identity in 629 aa overlap. Contains hydrop [...]
fbpA protein networkhttps://string-db.org/network/272631.gene:17573909Antigen 85A, mycolytransferase; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates [...]
fbpC protein networkhttps://string-db.org/network/272631.gene:17573910Antigen 85C, mycolyltransferase; May have a role in host tissue attachment, whereby ligands may include the serum protein fibronectin and small sugars.
ML0099 protein networkhttps://string-db.org/network/272631.gene:17573911Similar to M. tuberculosis Rv3802c, hypothetical protein, TR:O53581 (EMBL:AL123456) (336 aa); Fasta score E(): 0, 75.5% identity in 335 aa overlap.
fadD32 protein networkhttps://string-db.org/network/272631.gene:17573912Similar to several putative acyl-CoA synthases from M. tuberculosis e.g. M. tuberculosis Rv3801c, fadD32, putative acyl-CoA synthase, TR:O53580 (EMBL:AL123456) (637 aa); Fasta score E(): 0, 93.2% [...]
pks13 protein networkhttps://string-db.org/network/272631.gene:17573913Similar to many polyketide synthases from M. tuberculosis e.g. ppsA, M. tuberculosis phenolpthiocerol synthesis polyketide synthase, SW:PPSA_MYCTU (Q10977) (1876 aa); Fasta score E(): 0, 36.1% id [...]
accD4 protein networkhttps://string-db.org/network/272631.gene:17573914Similar to many acyl-CoA carboxylase subunits e.g. M. tuberculosis pccB, acetyl/propionyl-CoA carboxylase [beta] subunit, TR:O53578 (EMBL:AL123456) (518 aa); Fasta score E(): 0, 91.2% identity in [...]
embB protein networkhttps://string-db.org/network/272631.gene:17573916Putative arabinosyl transferase; Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan; Belongs to the emb family.
embA protein networkhttps://string-db.org/network/272631.gene:17573917Putative arabinosyl transferase; Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan; Belongs to the emb family.
embC protein networkhttps://string-db.org/network/272631.gene:17573918Putative arabinosyl transferase; Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan; Belongs to the emb family.
ML0107 protein networkhttps://string-db.org/network/272631.gene:17573919Putative membrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial [...]
ML0108 protein networkhttps://string-db.org/network/272631.gene:17573920Similar To M. tuberculosis Rv3791, putative oxidoreductase, SW:Y1J1_MYCTU (P72057) (254 aa); Fasta score E(): 0, 89.0% identity in 254 aa overlap and to other putative oxidoreductases from the sa [...]
ML0109 protein networkhttps://string-db.org/network/272631.gene:17573921Similar to M. tuberculosis Rv3790, putative oxidoreductase, TR:P72056 (EMBL:AL123456) (461 aa); Fasta score E(): 0, 86.6% identity in 461 aa overlap. Also similar to many bacterial putative oxido [...]
ML0110 protein networkhttps://string-db.org/network/272631.gene:17573922Possible membrane protein; Required for arabinosylation of arabinogalactan (AG), an essential component of the mycobacterial cell wall. Probably acts as an anchor protein recruiting AftA, the fir [...]
ML0112 protein networkhttps://string-db.org/network/272631.gene:17573924Putative ABC transporter component; Similar to M. tuberculosis Rv3783, integral membrane protein, TR:P72049 (EMBL:AL123456) (280 aa); Fasta score E(): 0, 84.3% identity in 280 aa overlap. Similar [...]
rfbE protein networkhttps://string-db.org/network/272631.gene:17573925Similar to M. tuberculosis Rv3782, putative glycosyl transferase, TR:P72048. Shows very weak similarity to proteins involved in lipopolysaccharide biosynthesis.
ML0114 protein networkhttps://string-db.org/network/272631.gene:17573926Similar to M. tuberculosis Rv3781, putative ABC transporter component, TR:P72047 (EMBL:AL123456) (273 aa); Fasta score E(): 0, 91.4% identity in 267 aa overlap. Similar to Yersinia enterocolitica [...]
ML0115 protein networkhttps://string-db.org/network/272631.gene:17573927Conserved hypothetical protein; Interacts with the core proteasome alpha-subunit (PrcA) through its C-terminal hydrophobic-tyrosine-X motif (HbYX motif). Interaction of Bpa with the proteasome st [...]
ML0116 protein networkhttps://string-db.org/network/272631.gene:17573928Putative membrane protein; Similar to M. tuberculosis Rv3779, unknown membrane protein, TR:P72045 (EMBL:AL123456) (666 aa); Fasta score E(): 0, 66.5% identity in 666 aa overlap. Contains hydropho [...]
ML0117 protein networkhttps://string-db.org/network/272631.gene:17573929Similar to M. tuberculosis Rv3778c, conserved hypothetical protein, TR:P72044 (EMBL:AL123456) (398 aa); Fasta score E(): 0, 83.4% identity in 398 aa overlap. Also similar to many bacterial hypoth [...]
ML0118 protein networkhttps://string-db.org/network/272631.gene:17573930Similar to M. tuberculosis Rv3777, putative oxidireductase, TR:P72043. Similar to many oxidoreductases from both bacteria and higher organisms e.g. Mus musculus cryZ, quinone oxidoreductase, SW:Q [...]
lipE protein networkhttps://string-db.org/network/272631.gene:17573932Probable hydrolase; Similar to M. tuberculosis Rv3775, probable hydrolase, TR:P72041 (EMBL:AL123456) (415 aa); Fasta score E(): 0, 84.7% identity in 406 aa overlap. Similar to bacterial esterases [...]
echA1 protein networkhttps://string-db.org/network/272631.gene:17573933Similar to M. tuberculosis Rv3774, putative enoyl-CoA hydratase, TR:P75019 (EMBL:AL123456) (274 aa); Fasta score E(): 0, 88.3% identity in 274 aa overlap. Similar to many e.g. Rattus norvegicus e [...]
ML0121 protein networkhttps://string-db.org/network/272631.gene:17573934Hypothetical protein; Shares region of weak similarity with Streptomyces coelicolor SC6A5.32C, hypothetical protein, TR:Q9X7X8 (EMBL:AL049485) (155 aa); Fasta score E(): 0.0056, 43.1% identity in [...]
ML0124 protein networkhttps://string-db.org/network/272631.gene:17573939Conserved hypothetical protein; Shows weak similarity to M. tuberculosis Rv2186c, hypothetical protein, TR:O53519 (EMBL:AL123456) (144 aa); Fasta score E(): 3.7e-06, 27.5% identity in 131 aa over [...]
ML0125 protein networkhttps://string-db.org/network/272631.gene:17573940Similar to M. tuberculosis Rv2958c, putative glycosyl transferase, TR:P95134 (EMBL:AL123456) (428 aa); Fasta score E(): 0, 74.6% identity in 418 aa overlap and Rv2962c, putative glycosyl transfer [...]
ML0126 protein networkhttps://string-db.org/network/272631.gene:17573941Hypothetical protein; Unknown function.
ML0127 protein networkhttps://string-db.org/network/272631.gene:17573942Hypothetical protein; Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosate [...]
ML0128 protein networkhttps://string-db.org/network/272631.gene:17573943Similar to M. tuberculosis Rv2958c, putative glycosyl transferase, TR:P95134 (EMBL:AL123456) (428 aa); Fasta score E(): 0, 75.1% identity in 417 aa overlap and Rv2962c, putative glycosyl transfer [...]
ML0129 protein networkhttps://string-db.org/network/272631.gene:17573944Conserved hypothetical protein; Involved in the reduction of the double bond between C-4 and C-5 during phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL [...]
ML0130 protein networkhttps://string-db.org/network/272631.gene:17573945Conserved hypothetical protein; Catalyzes the methylation of the lipid moiety of the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycoserosates to form phthiocerol dimy [...]
ML0131 protein networkhttps://string-db.org/network/272631.gene:17573946Putative oxidoreductase; Catalyzes the reduction of the keto moiety of phthiodiolone dimycocerosates (DIM B) and glycosylated phenolphthiodiolone dimycocerosates to form the intermediate compound [...]
fadD29 protein networkhttps://string-db.org/network/272631.gene:17573947Similar to several putative acyl-CoA synthases from M. tuberculosis e.g. M. tuberculosis Rv2950c, fadD29, putative acyl-CoA synthase, TR:P95141 (EMBL:AL123456) (619 aa); Fasta score E(): 0, 80.2% [...]
ML0133 protein networkhttps://string-db.org/network/272631.gene:17573948Conserved hypothetical protein; Removes the pyruvyl group from chorismate to provide 4- hydroxybenzoate (4HB). Involved in the synthesis of glycosylated p- hydroxybenzoic acid methyl esters (p-HB [...]
fadD22 protein networkhttps://string-db.org/network/272631.gene:17573949Putative acyl-CoA synthetase; Similar to M. tuberculosis Rv2948c, acyl-CoA synthase, TR:P96283 (EMBL:AL123456) (705 aa); Fasta score E(): 0, 75.9% identity in 705 aa overlap. Similar to many acyl [...]
ML0135 protein networkhttps://string-db.org/network/272631.gene:17573950Similar to many polyketide synthases from M. tuberculosis e.g. N-terminus is similar to Rv2947c, pks15, probable polyketide synthase, TR:P96284 (EMBL:Z83858) (496 aa); Fasta score E(): 0, 90.5% i [...]
lppX protein networkhttps://string-db.org/network/272631.gene:17573951Putative lipoprotein; Might be involved in translocating phthiocerol dimycocerosates (PDIM) from the cell membrane to the outer membrane; PDIM forms part of the cell wall; Belongs to the LppX/Lpr [...]
mmpL7 protein networkhttps://string-db.org/network/272631.gene:17573952Putative membrane protein; Similar to members of the M. tuberculosis mmpL family of membrane proteins e.g. Rv2942, mmpL7, putative membrane protein, SW:MML7_MYCTU (P96289) (920 aa); Fasta score E [...]
fadD28 protein networkhttps://string-db.org/network/272631.gene:17573953Similar to several putative acyl-CoA synthases from M. tuberculosis e.g. M. tuberculosis Rv2941, fadD29, putative acyl-CoA synthase, TR:P96290 (EMBL:AL123456) (580 aa); Fasta score E(): 0, 81.9% [...]
mas protein networkhttps://string-db.org/network/272631.gene:17573954Putative mycocerosic synthase; Similar to many polyketide synthases from M. tuberculosis e.g. Rv2940c, mas, mycocerosic acid synthase, TR:P96291 (EMBL:AL123456) (2111 aa); Fasta score E(): 0, 88. [...]
ML0141 protein networkhttps://string-db.org/network/272631.gene:17573956Hypothetical protein; Improbable CDS suggested by GC frameplot. Possibly the remains of a disrupted gene.
ML0142 protein networkhttps://string-db.org/network/272631.gene:17573957Possible membrane protein; Unknown function. Contains hydrophobic, possible membrane-spanning region.
pgi protein networkhttps://string-db.org/network/272631.gene:17573965Glucose-6-phosphate isomerase; Similar to M. tuberculosis Rv0946c, pgi, glucose-6-phosphate isomerase, SW:G6PI_MYCTU (P77895) (553 aa); Fasta score E(): 0, 85.5% identity in 552 aa overlap and My [...]
ML0151 protein networkhttps://string-db.org/network/272631.gene:17573966Similar to M. tuberculosis Rv0948c, hypothetical protein, SW:Y948_MYCTU (P71562) (105 aa); Fasta score E(): 1.9e-32, 83.8% identity in 105 aa overlap. Also similar to Streptomyces coelicolor SCD6 [...]
ML0152 protein networkhttps://string-db.org/network/272631.gene:17573967Hypothetical protein; Improbable CDS suggested by GC frameplot. Possibly the remains of a disrupted gene.
uvrD protein networkhttps://string-db.org/network/272631.gene:17573968Putative ATP-dependent DNA helicase; DNA-dependent ATPase, acting on dsDNA with a 3'-ssDNA tail, unwinding with 3'-to 5'-polarity. Also highly efficient on nicked DNA. Involved in the post-incisi [...]
ML0154 protein networkhttps://string-db.org/network/272631.gene:17573969Similar to M. tuberculosis Rv0950c, hypothetical protein, TR:P71560 (EMBL:AL123456) (332 aa); Fasta score E(): 0, 71.0% identity in 331 aa overlap. Shows weaker similarity to many bacterial hypot [...]
sucC protein networkhttps://string-db.org/network/272631.gene:17573970succinyl-CoA synthase [beta] chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus repres [...]
sucD protein networkhttps://string-db.org/network/272631.gene:17573971succinyl-CoA synthase [alpha] chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus repre [...]
ML0158 protein networkhttps://string-db.org/network/272631.gene:1757397334 kDa antigen; Similar to M. tuberculosis Rv0954, 34 kDa antigenic protein homologue, SW:34KD_MYCTU (P71556) (303 aa); Fasta score E(): 0, 55.8% identity in 312 aa overlap and to Mycobacterium p [...]
ML0159 protein networkhttps://string-db.org/network/272631.gene:17573974Putative membrane protein; Similar to M. tuberculosis Rv0955, possible membrane protein, SW:Y955_MYCTU (P71555) (455 aa); Fasta score E(): 0, 75.9% identity in 419 aa overlap. Previously sequence [...]
purN protein networkhttps://string-db.org/network/272631.gene:17573975Putative phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl- [...]
purH protein networkhttps://string-db.org/network/272631.gene:17573976Similar to M. tuberculosis Rv0957, purH, putative phosphoribosylaminoimidazolecarboxamide formyltransferase.
ML0169 protein networkhttps://string-db.org/network/272631.gene:17573984Similar to M. tuberculosis Rv0966c, hypothetical protein, SW:Y966_MYCTU (P71544) (230 aa); Fasta score E(): 0, 79.5% identity in 200 aa overlap. Also similar to Streptomyces coelicolor SCE6.30C, [...]
rpmF protein networkhttps://string-db.org/network/272631.gene:17573988Hypothetical protein (pseudogene); Probable ribosomal protein L32, rpmF,similar to many e.g. tr|Q9RL50|Q9RL50 PROBABLE 50S RIBOSOMAL PROTEIN (56 aa) E(): 1.5e-09; 63.462% identity in 52 aa overla [...]
ML0174 protein networkhttps://string-db.org/network/272631.gene:17573989Putative two-component response regulator; Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance a [...]
ML0175 protein networkhttps://string-db.org/network/272631.gene:17573990Putative two-component system sensor kinase; Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance [...]
ML0176 protein networkhttps://string-db.org/network/272631.gene:17573991Similar to M.tuberculosis Rv0983, probable serine protease, TR:O53896 (EMBL:AL123456) (464 aa); Fasta score E(): 0, 80.7% identity in 383 aa overlap and in part to M.tuberculosis htrA, putative s [...]
moaB protein networkhttps://string-db.org/network/272631.gene:17573992Similar to M.tuberculosis moaB2, putative molybdenum cofactor biosynthesis protein, TR:O53897 (EMBL:AL123456) (181 aa); Fasta score E(): 0, 92.7% identity in 179 aa overlap. Similar to many e.g. [...]
mscL protein networkhttps://string-db.org/network/272631.gene:17573993Putative mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the [...]
ML0180 protein networkhttps://string-db.org/network/272631.gene:17573995Similar to M.tuberculosis Rv0991c, hypothetical protein with Ser-rich C-terminus, TR:O05574 (EMBL:AL123456) (110 aa); Fasta score E(): 1.1e-23, 78.5% identity in 93 aa overlap. Similar to other b [...]
ML0181 protein networkhttps://string-db.org/network/272631.gene:17573996Similar to M.tuberculosis Rv0992c, conserved hypothetical protein, TR:O05575 (EMBL:AL123456) (197 aa); Fasta score E(): 0, 72.6% identity in 197 aa overlap. Similar to many hypothetical proteins [...]
galU protein networkhttps://string-db.org/network/272631.gene:17573997Similar to M.tuberculosis galU, Rv0993, UTP-glucose-1-phosphate uridylyltransferase, TR:O05576 (EMBL:AL123456) (306 aa); Fasta score E(): 0, 89.7% identity in 302 aa overlap. Similar to many e.g. [...]
moeA protein networkhttps://string-db.org/network/272631.gene:17573998Putative molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
rimJ protein networkhttps://string-db.org/network/272631.gene:17573999Similar to M.tuberculosis rimJ, Rv0995, possible acetyltransferase, TR:O05578 (EMBL:AL123456) (203 aa); Fasta score E(): 0, 86.0% identity in 200 aa overlap. Similar to Escherichia coli rimJ, rib [...]
ML0185 protein networkhttps://string-db.org/network/272631.gene:17574000Putative membrane protein; Similar to M.tuberculosis Rv0996, hypothetical protein, TR:O05579 (EMBL:AL123456) (358 aa); Fasta score E(): 0, 66.4% identity in 360 aa overlap. Previously sequenced a [...]
ML0187 protein networkhttps://string-db.org/network/272631.gene:17574003Similar to M. tuberculosis Rv0998, hypothetical protein, TR:O05581 (EMBL:AL123456) (333 aa); Fasta score E(): 0, 69.7% identity in 330 aa overlap. Contains Pfam match to entry PF00027 cNMP_bindin [...]
ML0188 protein networkhttps://string-db.org/network/272631.gene:17574004Hypothetical protein; Unknown function. Contains PS01047 Heavy-metal-associated domain.
ML0190 protein networkhttps://string-db.org/network/272631.gene:17574006Conserved hypothetical protein; Unknown but orthologue of equivalent to new M. tuberculosis CDS, Rv1000. Very similar to conserved hypothetical proteins in various bacteria e.g. Streptomyces coel [...]
ML0192 protein networkhttps://string-db.org/network/272631.gene:17574008Putative membrane protein; Similar to M. tuberculosis Rv1002c, probable membrane protein, TR:O05586 (EMBL:AL123456) (503 aa); Fasta score E(): 0, 80.4% identity in 510 aa overlap. Also similar to [...]
ML0193 protein networkhttps://string-db.org/network/272631.gene:17574009Conserved hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
cspA protein networkhttps://string-db.org/network/272631.gene:17574014Putative cold shock protein; Similar to M. tuberculosis cspA, Rv3648c, probable cold shock protein, SW:CSPA_MYCTU (O06360) (67 aa); Fasta score E(): 3.9e-27, 97.0% identity in 67 aa overlap. Simi [...]
ML0199 protein networkhttps://string-db.org/network/272631.gene:17574015ML0199 protein; Similar to M. tuberculosis Rv3647c, hypothetical protein, TR:O06361 (EMBL:AL123456) (192 aa); Fasta score E(): 0, 80.4% identity in 199 aa overlap. Previously sequenced as TR:O695 [...]
topA protein networkhttps://string-db.org/network/272631.gene:17574016Putative DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one s [...]
ML0201 protein networkhttps://string-db.org/network/272631.gene:17574017Putative membrane protein; Similar to M. tuberculosis Rv3645, probable transmembrane protein, TR:O06362 (EMBL:AL123456) (549 aa); Fasta score E(): 0, 85.3% identity in 530 aa overlap and to sever [...]
ML0202 protein networkhttps://string-db.org/network/272631.gene:17574018Similar to M. tuberculosis Rv3644c, hypothetical protein, TR:O06363 (EMBL:AL123456) (401 aa); Fasta score E(): 0, 84.4% identity in 404 aa overlap. Similar to the N-termini of many DNA polymerase [...]
ML0203 protein networkhttps://string-db.org/network/272631.gene:17574020Putative membrane protein; Similar to M. tuberculosis Rv3635, probable membrane protein, TR:O06372 (EMBL:AL123456) (591 aa); Fasta score E(): 0, 77.2% identity in 569 aa overlap. Previously seque [...]
rmlB2 protein networkhttps://string-db.org/network/272631.gene:17574021Putative sugar-nucleotide dehydratase; Similar to M. tuberculosis rmlB2, possible dTDP-Glucose 4,6-dehydratase, TR:O06373 (EMBL:AL123456) (314 aa); Fasta score E(): 0, 86.1% identity in 309 aa ov [...]
ML0205 protein networkhttps://string-db.org/network/272631.gene:17574022Putative membrane protein; Similar to M. tuberculosis Rv3629c, possible membrane protein, TR:O06378 (EMBL:AL123456) (365 aa); Fasta score E(): 0, 66.2% identity in 361 aa overlap. Similar to othe [...]
ML0207 protein networkhttps://string-db.org/network/272631.gene:17574024Putative glycosyltransferase; Similar to M. tuberculosis Rv3631, possible glycosyltransferase, TR:O06376 (EMBL:AL123456) (241 aa); Fasta score E(): 0, 80.8% identity in 239 aa overlap. Similar to [...]
ML0208 protein networkhttps://string-db.org/network/272631.gene:17574025Putative membrane protein; Similar to M. tuberculosis Rv3632, hypothetical protein, TR:O06375 (EMBL:AL123456) (114 aa); Fasta score E(): 0, 82.0% identity in 111 aa overlap. Previously sequenced [...]
ppa protein networkhttps://string-db.org/network/272631.gene:17574027Putative inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
ML0211 protein networkhttps://string-db.org/network/272631.gene:17574028Putative carboxypeptidase; Similar to M. tuberculosis Rv3627c, possible penicillin-binding protein, TR:O06380 (EMBL:AL123456) (461 aa); Fasta score E(): 0, 76.0% identity in 462 aa overlap. Shows [...]
mesJ protein networkhttps://string-db.org/network/272631.gene:17574030Conserved hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine i [...]
hpt protein networkhttps://string-db.org/network/272631.gene:17574031Putative hypoxanthine phosphoribosyltransferase; Similar to M. tuberculosis hpt, Rv3624c, probable hypoxanthine-guanine phosphoribosyltransferase, SW:HPRT_MYCTU (O06383) (216 aa); Fasta score E() [...]
ftsH protein networkhttps://string-db.org/network/272631.gene:17574039Putative integral membrane peptidase; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membran [...]
folE protein networkhttps://string-db.org/network/272631.gene:17574040Similar to M. tuberculosis folE, Rv3609c, GTP cyclohydrolase I, SW:GCH1_MYCTU (O06273) (202 aa); Fasta score E(): 0, 82.0% identity in 205 aa overlap. Similar to many e.g. Bacillus subtilis mtrA, [...]
folP protein networkhttps://string-db.org/network/272631.gene:17574041Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate, the immediate precurso [...]
folB protein networkhttps://string-db.org/network/272631.gene:17574042Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin, 7,8-dihydromonapterin and 7,8- dihydroxanthopterin, respectively, in eq [...]
folK protein networkhttps://string-db.org/network/272631.gene:17574043Similar to M. tuberculosis folK, Rv3607c, probable 2-amino-4-hydroxy-6-hydroxymethyldihydropterine pyrophosphokinase, SW:HPPK_MYCTU (O06276) (188 aa); Fasta score E(): 0, 63.2% identity in 190 aa [...]
ML0227 protein networkhttps://string-db.org/network/272631.gene:17574044Putative membrane protein; Similar to M. tuberculosis Rv3605c, hypothetical protein, TR:O06277 (EMBL:AL123456) (158 aa); Fasta score E(): 0, 85.4% identity in 158 aa overlap. Previously sequenced [...]
ML0228 protein networkhttps://string-db.org/network/272631.gene:17574045Putative membrane protein; Similar to M. tuberculosis Rv3604c, putative membrane protein, TR:O06278 (EMBL:AL123456) (462 aa); Fasta score E(): 0, 59.7% identity in 432 aa overlap. Previously sequ [...]
ML0229 protein networkhttps://string-db.org/network/272631.gene:17574046Similar to M. tuberculosis Rv3603c, hypothetical protein, TR:O06279 (EMBL:AL123456) (303 aa); Fasta score E(): 0, 67.8% identity in 311 aa overlap. Similar to the N-terminal half of Streptomyces [...]
panC protein networkhttps://string-db.org/network/272631.gene:17574047Putative pantoate-[beta]-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate sy [...]
panD protein networkhttps://string-db.org/network/272631.gene:17574048Putative aspartate-1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
ML0232 protein networkhttps://string-db.org/network/272631.gene:17574049Conserved hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
lysS protein networkhttps://string-db.org/network/272631.gene:17574050Putative lysyl-tRNA synthase; Similar to M. tuberculosis lysS, Rv3598c, putative lysyl-tRNA synthase, SW:SYK_MYCTU (O06284) (505 aa); Fasta score E(): 0, 85.4% identity in 501 aa overlap. Similar [...]
lsr2 protein networkhttps://string-db.org/network/272631.gene:17574051Lsr2 protein (15 kDa antigen); DNA-bridging protein that has both architectural and regulatory roles. Influences the organization of chromatin and gene expression by binding non-specifically to D [...]
clpC protein networkhttps://string-db.org/network/272631.gene:17574052Similar to M. tuberculosis clpC, ATP-dependent Clp protease, SW:CLPC_MYCTU (O06286) (848 aa); Fasta score E(): 0, 97.2% identity in 845 aa overlap. Similar to many e.g. Bacillus subtilis clpC, ne [...]
pabB protein networkhttps://string-db.org/network/272631.gene:17574053EC_number=4.1.3.-; Similar to M. tuberculosis pabB, Rv1005c, putative para-aminobenzoate synthase component I, TR:O05591 (EMBL:Z94752) (458 aa); Fasta score E(): 0, 79.1% identity in 412 aa overl [...]
metS protein networkhttps://string-db.org/network/272631.gene:17574055Putative methionyl-tRNA synthase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs [...]
ML0239 protein networkhttps://string-db.org/network/272631.gene:17574056Conserved hypothetical protein; Similar to M. tuberculosis ycfH, Rv1008, conserved hypothetical protein, TR:O08343 (EMBL:AL123456) (264 aa); Fasta score E(): 0, 82.3% identity in 260 aa overlap. [...]
ML0240 protein networkhttps://string-db.org/network/272631.gene:17574057Similar to M. tuberculosis Rv1009, conserved hypothetical protein, TR:O05594 (EMBL:AL123456) (362 aa); Fasta score E(): 0, 82.3% identity in 361 aa overlap. The C-terminus is similar to a region [...]
ksgA protein networkhttps://string-db.org/network/272631.gene:17574058Putative dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May [...]
ML0242 protein networkhttps://string-db.org/network/272631.gene:17574059Putative isopentenyl monophosphate kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
ML0243 protein networkhttps://string-db.org/network/272631.gene:17574060Similar to several putative acyl-CoA synthases from M.tuberculosis e.g. pks16, Rv1013, possible polyketide synthase, TR:O05598 (EMBL:AL123456) (544 aa); Fasta score E(): 0, 82.2% identity in 544 [...]
pth protein networkhttps://string-db.org/network/272631.gene:17574061Putative peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
rplY protein networkhttps://string-db.org/network/272631.gene:17574062Putative 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protei [...]
lpqT protein networkhttps://string-db.org/network/272631.gene:17574063Putative lipoprotein; Similar to M. tuberculosis lpqT, putative lipoprotein, SW:LPQT_MYCTU (P96384) (226 aa); Fasta score E(): 0, 67.1% identity in 213 aa overlap. Also similar to M. tuberculosis [...]
arsC protein networkhttps://string-db.org/network/272631.gene:17574064Putative arsenate reductase; Similar to many e.g. Escherichia coli arsC, arsenate reductase, SW:ARC1_ECOLI (P08692) (141 aa); Fasta score E(): 1.7e-07, 38.8% identity in 103 aa overlap. Similar t [...]
prsA protein networkhttps://string-db.org/network/272631.gene:17574065Putative ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from AT [...]
glmU protein networkhttps://string-db.org/network/272631.gene:17574066Putative UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domai [...]
mfd protein networkhttps://string-db.org/network/272631.gene:17574070Putative transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its tru [...]
eno protein networkhttps://string-db.org/network/272631.gene:17574073Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase f [...]
ML0256 protein networkhttps://string-db.org/network/272631.gene:17574074Putative membrane protein; Similar to M. tuberculosis Rv1024, hypothetical protein, TR:P96376 (EMBL:AL123456) (228 aa); Fasta score E(): 0, 70.5% identity in 220 aa overlap. Contains hydrophobic, [...]
ML0257 protein networkhttps://string-db.org/network/272631.gene:17574075Similar to M. tuberculosis Rv1025, hypothetical protein, TR:P96375 (EMBL:AL123456) (155 aa); Fasta score E(): 0, 85.1% identity in 154 aa overlap. Also similar to hypothetical proteins from Therm [...]
ML0258 protein networkhttps://string-db.org/network/272631.gene:17574076Hypothetical protein; Similar to M. tuberculosis Rv1026, hypothetical protein, TR:P96374 (EMBL:AL123456) (319 aa); Fasta score E(): 0, 77.6% identity in 321 aa overlap. Similar to many bacterial [...]
ML0269 protein networkhttps://string-db.org/network/272631.gene:17574088Putative F420-dependent glucose-6-phosphate dehydrogenase; Catalyzes the coenzyme F420-dependent oxidation of glucose 6- phosphate (G6P) to 6-phosphogluconolactone. Appears to have a role in resi [...]
ML0270 protein networkhttps://string-db.org/network/272631.gene:17574089Similar to M. tuberculosis Rv0406c, hypothetical protein, TR:O86336 (EMBL:AL123456) (272 aa); Fasta score E(): 0, 74.9% identity in 243 aa overlap. Shows similarity to members of the metallo-beta [...]
ML0271 protein networkhttps://string-db.org/network/272631.gene:17574090Putative membrane protein; Similar to M. tuberculosis Rv0401, putative membrane protein, TR:P95210 (EMBL:AL123456) (123 aa); Fasta score E(): 1.9e-32, 66.9% identity in 121 aa overlap. Similar to [...]
metZ protein networkhttps://string-db.org/network/272631.gene:17574094Putative o-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
ML0276 protein networkhttps://string-db.org/network/272631.gene:17574095Similar to M. tuberculosis Rv0390, hypothetical protein, TR:P95198 (AL123456) (140 aa); Fasta score E(): 0, 79.0% identity in 138 aa overlap. Also similar to Rickettsia prowazekii RP600, hypothet [...]
ML0279 protein networkhttps://string-db.org/network/272631.gene:17574098Similar to M. tuberculosis Rv0356c, hypothetical protein, TR:O06307 (EMBL:AL123456) (214 aa); Fasta score E(): 0, 73.4% identity in 214 aa overlap. Previously sequenced as TR:O69594 (EMBL:AL02351 [...]
purA protein networkhttps://string-db.org/network/272631.gene:17574099Putative adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belon [...]
ML0281 protein networkhttps://string-db.org/network/272631.gene:17574100Similar to M. tuberculosis Rv0358, hypothetical protein, TR:O06308 (EMBL:AL123456) (215 aa); Fasta score E(): 0, 62.4% identity in 229 aa overlap. Previously sequenced as TR:O69596 (EMBL:AL023514 [...]
ML0283 protein networkhttps://string-db.org/network/272631.gene:17574102Similar to many cation-efflux transporter components e.g. Alcaligenes eutrophus czcD, cobalt-zinc-cadmium resistance protein, SW:CZCD_ALCEU (P13512) (316 aa); Fasta score E(): 3.8e-22, 36.4% iden [...]
ML0284 protein networkhttps://string-db.org/network/272631.gene:17574103Similar to M. tuberculosis Rv0360c, hypothetical protein, TR:O06310 (EMBL:AL123456) (145 aa); Fasta score E(): 0, 85.4% identity in 137 aa overlap and Streptomyces coelicolor SCH10.25C, hypotheti [...]
ML0285 protein networkhttps://string-db.org/network/272631.gene:17574104Putative membrane protein; Similar to M. tuberculosis Rv0361, possible membrane protein, TR:O06311 (EMBL:AL123456) (275 aa); Fasta score E(): 0, 58.6% identity in 292 aa overlap. Previously seque [...]
fba protein networkhttps://string-db.org/network/272631.gene:17574105Putative fructose bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bi [...]
ML0287 protein networkhttps://string-db.org/network/272631.gene:17574106Putative membrane protein; Similar to M. tuberculosis Rv0364, hypothetical protein, SW:Y364_MYCTU (O06314) (227 aa); Fasta score E(): 0, 66.1% identity in 227 aa overlap. Similar to many dedA-fam [...]
thiC protein networkhttps://string-db.org/network/272631.gene:17574113Putative thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-me [...]
thiD protein networkhttps://string-db.org/network/272631.gene:17574114Putative phosphomethylpyrimidine kinase; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.
thiG protein networkhttps://string-db.org/network/272631.gene:17574116Putative thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocar [...]
ML0298 protein networkhttps://string-db.org/network/272631.gene:17574117Similar to M. tuberculosis Rv0416, conserved hypothetical protein, TR:P96262 (EMBL:AL123456) (68 aa); Fasta score E(): 5.9e-17, 71.6% identity in 74 aa overlap. Similar to bacterial hypothetical [...]
ML0299 protein networkhttps://string-db.org/network/272631.gene:17574118Putative oxidoreductase; Similar to M. tuberculosis Rv0415, conserved hypothetical protein, TR:P96261 (EMBL:AL123456) (340 aa); Fasta score E(): 0, 82.0% identity in 338 aa overlap. Shows weak si [...]
thiE protein networkhttps://string-db.org/network/272631.gene:17574119Putative thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to for [...]
glnH protein networkhttps://string-db.org/network/272631.gene:17574122Similar to M. tuberculosis glnH, Rv0411c, putative glutamine-binding protein, TR:P96257 (EMBL:AL123456) (328 aa); Fasta score E(): 0, 79.3% identity in 328 aa overlap. Similar to many bacterial s [...]
pknG protein networkhttps://string-db.org/network/272631.gene:17574123Similar to M. tuberculosis pknG, Rv0410c, putative serine/threonine protein kinase, TR:P96256 (EMBL:AL123456) (750 aa); Fasta score E(): 0, 83.1% identity in 756 aa overlap. Similar to many bacte [...]
ML0308 protein networkhttps://string-db.org/network/272631.gene:17574127Similar to hypothetical proteins from methanobacteria e.g. Methanobacterium thermoautotrophicum MTH1801, hypothetical protein, TR:O27829 (EMBL:AE000934) (224 aa); Fasta score E(): 3.6e-24, 39.3% [...]
pssA protein networkhttps://string-db.org/network/272631.gene:17574129Similar to M. tuberculosis pssA, Rv0436c, CDP-diacylglycerol-serine o-phosphatidyltransferase, SW:PSS_MYCTU (P96282) (286 aa); Fasta score E(): 0, 77.9% identity in 285 aa overlap. Similar to man [...]
ML0311 protein networkhttps://string-db.org/network/272631.gene:17574130Conserved hypothetical protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
ML0314 protein networkhttps://string-db.org/network/272631.gene:17574133Putative esterase; Similar to M. tuberculosis lipU, Rv1076, probable esterase, TR:O53424 (EMBL:AL123456) (297 aa); Fasta score E(): 0, 79.7% identity in 296 aa overlap. Also similar to other puta [...]
ML0315 protein networkhttps://string-db.org/network/272631.gene:17574134Similar to M. tuberculosis Rv0068, putative oxidoreductase, TR:O53613 (EMBL:AL123456) (303 aa); Fasta score E(): 0, 73.9% identity in 306 aa overlap and to other M. tuberculosis putative oxidored [...]
ML0316 protein networkhttps://string-db.org/network/272631.gene:17574135Similar to M. tuberculosis Rv0067c, putative transcriptional regulator, TR:O53612 (EMBL:AL123456) (189 aa); Fasta score E(): 0, 68.8% identity in 189 aa overlap. Similar to many putative transcri [...]
groEL2 protein networkhttps://string-db.org/network/272631.gene:1757413660 kDa chaperonin 2; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
lpqE protein networkhttps://string-db.org/network/272631.gene:17574138Putative lipoprotein; Similar to M. tuberculosis lpqE, Rv3584, putative lipoprotein, TR:O53569 (EMBL:AL123456) (182 aa); Fasta score E(): 0, 63.4% identity in 175 aa overlap. Previously sequenced [...]
ML0320 protein networkhttps://string-db.org/network/272631.gene:17574139Similar to M. tuberculosis Rv3583c, putative transcription factor, TR:O53568 (EMBL:AL123456) (162 aa); Fasta score E(): 0, 97.5% identity in 162 aa overlap. Shows weak similarity to Myxococcus xa [...]
ML0321 protein networkhttps://string-db.org/network/272631.gene:17574140Putative 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
ML0322 protein networkhttps://string-db.org/network/272631.gene:17574141Putative 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of i [...]
cysS protein networkhttps://string-db.org/network/272631.gene:17574142Putative cysteinyl-tRNA synthase; Similar to M. tuberculosis cysS, Rv3580c, cysteinyl-tRNA synthetase, SW:SYC1_MYCTU (P96862) (469 aa); Fasta score E(): 0, 86.5% identity in 467 aa overlap. Simil [...]
ML0324 protein networkhttps://string-db.org/network/272631.gene:17574143Similar to M. tuberculosis Rv3579c, putative methyltransferase, TR:P96861 (EMBL:AL123456) (322 aa); Fasta score E(): 0, 84.1% identity in 277 aa overlap. Similar Streptomyces actuosus nhs, 23S rR [...]
ML0325 protein networkhttps://string-db.org/network/272631.gene:17574144Hypothetical protein; Unknown function. Possibly the remains of a disrupted gene.
ML0333 protein networkhttps://string-db.org/network/272631.gene:17574152Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
ML0335 protein networkhttps://string-db.org/network/272631.gene:17574154Putative ABC-transporter transmembrane protein; Similar in part to M. tuberculosis Rv2060, conserved hypothetical protein, TR:O86339 (EMBL:AL123456) (133 aa); Fasta score E(): 0, 80.3% identity i [...]
ML0336 protein networkhttps://string-db.org/network/272631.gene:17574155Similar to many putative ABC-tranporter ATP-binding proteins e.g. Chlamydia trachomatis troB, ABC transporter ATPase, TR:O87477 (EMBL:AF077010) (286 aa); Fasta score E(): 4.7e-16, 31.4% identity [...]
ML0337 protein networkhttps://string-db.org/network/272631.gene:17574156Shows weak similarity to periplasmic solute-binding proteins e.g. Synechocystis sp. (strain PCC 6803) mntC, periplasmic-binding protein, TR:Q55280 (EMBL:L34630) (330 aa); Fasta score E(): 0.0001, [...]
ML0348 protein networkhttps://string-db.org/network/272631.gene:17574167Similar to M. tuberculosis Rv3520c, possible coenzyme F420-dependent enzyme, TR:O53565 (EMBL:AL123456) (347 aa); Fasta score E(): 0, 86.8% identity in 342 aa overlap. Shows weak similarity to Met [...]
ilvX protein networkhttps://string-db.org/network/272631.gene:17574173Similar to M. tuberculosis ilvX, putative acetohydroxyacid synthase I large subunit, TR:O53554 (EMBL:AL123456) (515 aa); Fasta score E(): 0, 82.9% identity in 515 aa overlap. Similar to Escherich [...]
ML0363 protein networkhttps://string-db.org/network/272631.gene:17574182Possible secreted protein; Similar to M. tuberculosis Rv3444c, esat6-family protein, TR:O06261 (EMBL:Al123456) (100 aa); Fasta score E(): 3.3e-20, 71.2% identity in 73 aa overlap and others of th [...]
rplM protein networkhttps://string-db.org/network/272631.gene:1757418350S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages [...]
rpsI protein networkhttps://string-db.org/network/272631.gene:17574184Similar to M. tuberculosis rpsI, 30S ribosomal protein S9, SW:RS9_MYCTU (O06259) (151 aa); Fasta score E(): 0, 83.2% identity in 155 aa overlap. Previously sequenced as SW:RS9_MYCLE (P40828) (153 [...]
mrsA protein networkhttps://string-db.org/network/272631.gene:17574185Putative phosphoglucomutase/phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
ML0369 protein networkhttps://string-db.org/network/272631.gene:17574188Hypothetical protein; Unknown function. Previously sequenced as TR:Q49877 (EMBL:U00020) (118 aa); Fasta score E(): 0, 100.0% identity in 118 aa overlap.
ML0370 protein networkhttps://string-db.org/network/272631.gene:17574189Similar to M. tuberculosis Rv3438, conserved hypothetical protein, TR:O06255 (EMBL:AL123456) (280 aa); Fasta score E(): 0, 80.6% identity in 279 aa overlap. Previously sequenced as TR:Q49872 (EMB [...]
glmS protein networkhttps://string-db.org/network/272631.gene:17574190Putative glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
ML0373 protein networkhttps://string-db.org/network/272631.gene:17574192Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which i [...]
alr protein networkhttps://string-db.org/network/272631.gene:17574194Putative alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
ML0376 protein networkhttps://string-db.org/network/272631.gene:17574195Putative membrane protein; Unknown function. Contains hydrophobic, possible membrane-spanning region near the N-terminus.
ML0377 protein networkhttps://string-db.org/network/272631.gene:17574196tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with a [...]
ML0378 protein networkhttps://string-db.org/network/272631.gene:17574197Similar to M. tuberculosis rimI, Rv3420c, putative ribosomal protein S18 acetyltransferase, TR:Q50708 (EMBL:Z77165) (158 aa); Fasta score E(): 0, 72.1% identity in 154 aa overlap in the C-terminu [...]
gcp protein networkhttps://string-db.org/network/272631.gene:17574198Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is invo [...]
groES protein networkhttps://string-db.org/network/272631.gene:1757419910 kD chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
groEL1 protein networkhttps://string-db.org/network/272631.gene:1757420060 kDa chaperonin 1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
whiB3 protein networkhttps://string-db.org/network/272631.gene:17574201Putative transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
ML0383 protein networkhttps://string-db.org/network/272631.gene:17574202Similar to M. tuberculosis Rv3415c, conserved hypothetical protein, TR:Q50711 (EMBL:AL123456) (275 aa); Fasta score E(): 0, 73.6% identity in 277 aa overlap. Previously sequenced as TR:Q49858 (EM [...]
ML0386 protein networkhttps://string-db.org/network/272631.gene:17574205Similar to M. tuberculosis Rv3412, conserved hypothetical protein, SW:YY12_MYCTU (Q50714) (136 aa); Fasta score E(): 0, 93.4% identity in 136 aa overlap. Previously sequenced as SW:YY12_MYCLE (Q4 [...]
guaB2 protein networkhttps://string-db.org/network/272631.gene:17574206Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo [...]
guaB3 protein networkhttps://string-db.org/network/272631.gene:17574207Similar to M. tuberculosis guaB3, Rv3410c, putative inosine-5'-monophosphate dehydrogenase, SW:YY10_MYCTU (Q50716) (375 aa); Fasta score E(): 0, 90.5% identity in 368 aa overlap. This ORF is simi [...]
choD protein networkhttps://string-db.org/network/272631.gene:17574208Putative cholesterol oxidase; Similar to M. tuberculosis choD, Rv3409c, putative cholesterol oxidase, TR:Q57307 (EMBL:Al123456) (578 aa); Fasta score E(): 0, 88.6% identity in 569 aa overlap. Sim [...]
ML0392 protein networkhttps://string-db.org/network/272631.gene:17574211Putative sugar phosphorylase; Similar to M. tuberculosis Rv3401, conserved hypothetical protein, SW:YY01_MYCTU (Q50724) (786 aa); Fasta score E(): 0, 91.4% identity in 782 aa overlap. Shows weak [...]
ML0393 protein networkhttps://string-db.org/network/272631.gene:17574212Putative hydrolase; Similar to M. tuberculosis Rv3400, hypothetical protein, SW:YY00_MYCTU (Q50725) (262 aa); Fasta score E(): 0, 74.4% identity in 262 aa overlap. Previously sequenced as SW:YY00 [...]
guaA protein networkhttps://string-db.org/network/272631.gene:17574214Putative GMP synthase; Catalyzes the synthesis of GMP from XMP.
ML0396 protein networkhttps://string-db.org/network/272631.gene:17574215Similar to M. tuberculosis Rv0046c, conserved hypothetical protein, TR:P71703 (EMBL:AL123456) (367 aa); Fasta score E(): 0, 91.8% identity in 366 aa overlap. Similar to other bacterial hypothetic [...]
ML0397 protein networkhttps://string-db.org/network/272631.gene:17574216Putative transporter protein; C-terminal half is similar to sugar permeases e.g. Escherichia coli AraH, L-arabinose transport system permease protein, SW:ARAH_ECOLI (P08532) (329 aa); Fasta score [...]
ML0398 protein networkhttps://string-db.org/network/272631.gene:17574217Similar to many D-ribose-binding proteins e.g. Bacillus subtilis rbsB, D-ribose-binding protein precursor, SW:RBSB_BACSU (P36949) (305 aa); Fasta score E(): 2e-16, 32.6% identity in 273 aa overla [...]
ML0405 protein networkhttps://string-db.org/network/272631.gene:17574224Similar to M. tuberculosis Rv3616c, conserved hypothetical protein, TR:O06267 (EMBL:AL123456) (392 aa); Fasta score E(): 0, 62.7% identity in 394 aa overlap and to Rv3864, hypothetical protein, T [...]
ML0406 protein networkhttps://string-db.org/network/272631.gene:17574225Similar to M. tuberculosis Rv3615c, conserved hypothetical protein, TR:O06268 (EMBL:AL123456) (103 aa); Fasta score E(): 4.1e-19, 60.9% identity in 92 aa overlap and to Rv3865, hypothetical prote [...]
ML0407 protein networkhttps://string-db.org/network/272631.gene:17574226Similar to M. tuberculosis Rv3614c, conserved hypothetical protein, TR:O06269 (EMBL:AL123456) (184 aa); Fasta score E(): 0, 71.5% identity in 186 aa overlap and to Rv3867, hypothetical protein, T [...]
ML0410 protein networkhttps://string-db.org/network/272631.gene:17574229Similar to M. tuberculosis PE-family proteins e.g. Rv2107, PE-family protein, TR:O33243 (EMBL:AL123456) (98 aa); Fasta score E(): 4.7e-08, 44.7% identity in 85 aa overlap. Contains Pfam match to [...]
ML0411 protein networkhttps://string-db.org/network/272631.gene:17574230Serine-rich antigen; Similar to M. tuberculosis PPE-family proteins e.g. Rv2108, PPE-family protein, TR:P95315 (EMBL:AL123456) (243 aa); Fasta score E(): 5.8e-17, 34.4% identity in 212 aa overlap [...]
otsB2 protein networkhttps://string-db.org/network/272631.gene:17574233Putative trehalose-6-phosphate phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
ML0418 protein networkhttps://string-db.org/network/272631.gene:17574237Putative oxidoreductase; Similar to M. tuberculosis Rv3368c, conserved hypothetical protein, TR:O50397 (EMBL:AL123456) (214 aa); Fasta score E(): 0, 81.9% identity in 210 aa overlap. Shows weak s [...]
ML0419 protein networkhttps://string-db.org/network/272631.gene:17574238Putative tRNA/rRNA methyltransferase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltr [...]
bcp protein networkhttps://string-db.org/network/272631.gene:17574243Putative antioxidant protein; Similar to M. tuberculosis bcp, Rv2521, bacterioferritin comigratory protein, TR:O5322 (EMBL:AL123456) (157 aa); Fasta score E(): 0, 79.6% identity in 157 aa overlap [...]
ML0425 protein networkhttps://string-db.org/network/272631.gene:17574244Putative membrane protein; Similar to M. tuberculosis Rv2520c, hypothetical protein, TR:O53225 (EMBL:AL123456) (75 aa); Fasta score E(): 2.2e-15, 57.3% identity in 75 aa overlap. Previously seque [...]
lppS protein networkhttps://string-db.org/network/272631.gene:17574246Putative secreted protein; Similar to M. tuberculosis lppS, Rv2518c, putative lipoprotein, TR:O53223 (EMBL:AL021185) (408 aa); Fasta score E(): 0, 82.6% identity in 403 aa overlap. Does not conta [...]
ML0427 protein networkhttps://string-db.org/network/272631.gene:17574248Putative oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
ML0429 protein networkhttps://string-db.org/network/272631.gene:17574250Similar to M. tuberculosis Rv2509, putative oxidoreductase, TR:O06172 (EMBL:AL123456) (268 aa); Fasta score E(): 0, 88.8% identity in 267 aa overlap. Similar to many putative dehydrogenases. Prev [...]
ML0430 protein networkhttps://string-db.org/network/272631.gene:17574251Putative membrane protein; Similar to M. tuberculosis Rv2508c, putative membrane protein, TR:O06171 (EMBL:AL123456) (445 aa); Fasta score E(): 0, 75.7% identity in 441 aa overlap. Also similar to [...]
ML0447 protein networkhttps://string-db.org/network/272631.gene:17574268Hypothetical protein; Similar to region of cytochrome P450s e.g. Bacillus megaterium CYP102A1, cytochrome P450(BM-3), SW:CPXB_BACME (P14779) (1048 aa); Fasta score E(): 0.00033, 31.8% identity in [...]
ML0448 protein networkhttps://string-db.org/network/272631.gene:17574269Hypothetical protein; Unknown function. Previously sequenced as TR:O07143 (EMBL:Z96801) (90 aa); Fasta score E(): 0, 100.0% identity in 90 aa overlap.
ML0450 protein networkhttps://string-db.org/network/272631.gene:17574271Putative pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by [...]
ML0451 protein networkhttps://string-db.org/network/272631.gene:17574272Similar to M. tuberculosis Rv2609c, conserved hypothetical protein, TR:O06205 (EMBL:AL123456) (351 aa); Fasta score E(): 0, 77.7% identity in 336 aa overlap. Similar, in part, to hypothetical pro [...]
ML0452 protein networkhttps://string-db.org/network/272631.gene:17574273Putative glycosyltransferase; Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans [...]
ML0453 protein networkhttps://string-db.org/network/272631.gene:17574274Similar to M. tuberculosis Rv2611c, conserved hypothetical protein, TR:O06203 (EMBL:AL123456) (316 aa); Fasta score E(): 0, 71.5% identity in 312 aa overlap. Shows weak similarity to putative acy [...]
pgsA protein networkhttps://string-db.org/network/272631.gene:17574275Similar to M. tuberculosis pgsA, Rv2612c, putative CDP-alcohol phosphatidyltransferases, TR:O06202 (EMBL:AL123456) (217 aa); Fasta score E(): 0, 79.3% identity in 213 aa overlap. Shows weak simil [...]
ML0455 protein networkhttps://string-db.org/network/272631.gene:17574276Similar to M. tuberculosis Rv2613c, conserved hypothetical protein, TR:O06201 (EMBL:AL123456) (195 aa); Fasta score E(): 0, 84.7% identity in 196 aa overlap. Similar to many HIT-family hypothetic [...]
thrS protein networkhttps://string-db.org/network/272631.gene:17574277threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor en [...]
ML0458 protein networkhttps://string-db.org/network/272631.gene:17574279Similar to putative oxidoreductases from both bacteria and eukaryotes e.g. Schizosaccharomyces pombe SPBC215.11C, putative aldo-keto reductase, TR:O94315 (EMBL:AL033534) (306 aa); Fasta score E() [...]
ML0466 protein networkhttps://string-db.org/network/272631.gene:17574287Possible secreted protein; Similar to Streptomyces coelicolor SC6A5.23, hypothetical protein, TR:Q9X7W9 (EMBL:AL049485) (261 aa); Fasta score E(): 9.5e-26, 36.4% identity in 253 aa overlap. Previ [...]
dedA protein networkhttps://string-db.org/network/272631.gene:17574288Putative membrane protein; Similar to M. tuberculosis dedA, Rv2637, dedA-family protein, SW:YQ37_MYCTU (P71936) (218 aa); Fasta score E(): 0, 82.8% identity in 209 aa overlap. Similar to many ded [...]
ML0468 protein networkhttps://string-db.org/network/272631.gene:17574289Putative membrane protein; Similar to bacterial hypothetical proteins e.g. Aeropyrum pernix APE0183, hypothetical protein, TR:Q9YFR6 (EMBL:AP000058) (270 aa); Fasta score E(): 7.2e-07, 26.2% iden [...]
ML0470 protein networkhttps://string-db.org/network/272631.gene:17574291Hypothetical protein; Unknown function. Previously sequenced as TR:O07161 (EMBL:Z96801) (96 aa); Fasta score E(): 0, 100.0% identity in 96 aa overlap.
ML0472 protein networkhttps://string-db.org/network/272631.gene:17574293Hypothetical protein; Improbable CDS suggested by GC frameplot and codon usage plots. Possibly the remains of a disrupted gene.
ML0473 protein networkhttps://string-db.org/network/272631.gene:17574294Hypothetical protein; Improbable CDS suggested by GC frameplot and codon usage plots. Possibly the remains of a disrupted gene.
ML0474 protein networkhttps://string-db.org/network/272631.gene:17574295Conserved hypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled t [...]
ML0475 protein networkhttps://string-db.org/network/272631.gene:17574296Similar to M. tuberculosis Rv2603c, conserved hypothetical protein, SW:YQ03_MYCTU (O33214) (251 aa); Fasta score E(): 0, 92.4% identity in 251 aa overlap. Similar to many bacterial hypothetical p [...]
ruvC protein networkhttps://string-db.org/network/272631.gene:17574302Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands [...]
ruvA protein networkhttps://string-db.org/network/272631.gene:17574303Holliday junction DNA helicase component; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote s [...]
ruvB protein networkhttps://string-db.org/network/272631.gene:17574304Holliday junction helicase component; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote stran [...]
fadD9 protein networkhttps://string-db.org/network/272631.gene:17574305Putative acyl-CoA synthetase; Similar to M. tuberculosis fadD9, Rv2590, putative acyl-CoA synthetase, TR:Q5063 (EMBL:Al123456) (1168 aa); Fasta score E(): 0, 68.0% identity in 1178 aa overlap1. S [...]
gabT protein networkhttps://string-db.org/network/272631.gene:17574306Similar to M. tuberculosis gabT, Rv2589, 4-aminobutyrate aminotransferase, SW:GABT_MYCTU (Q50632) (449 aa); Fasta score E(): 0, 83.7% identity in 449 aa overlap. Similar to many e.g. Escherichia [...]
ML0486 protein networkhttps://string-db.org/network/272631.gene:17574307Putative secreted protein; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and [...]
secD protein networkhttps://string-db.org/network/272631.gene:17574308Putative protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complet [...]
secF protein networkhttps://string-db.org/network/272631.gene:17574309Putative protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complet [...]
ML0489 protein networkhttps://string-db.org/network/272631.gene:17574310Putative lipoprotein; Similar to M. tuberculosis Rv2585c, hypothetical protein, SW:YP85_MYCTU (Q50636) (557 aa); Fasta score E(): 0, 78.9% identity in 546 aa overlap. Previously sequenced as SW:Y [...]
relA protein networkhttps://string-db.org/network/272631.gene:17574312Putative GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in respons [...]
ppiB protein networkhttps://string-db.org/network/272631.gene:17574313Putative peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity) [...]
ML0493 protein networkhttps://string-db.org/network/272631.gene:17574314Putative hydrolase; Similar to M. tuberculosis Rv2581c, hypothetical protein, SW:YP81_MYCTU (Q50640) (224 aa); Fasta score E(): 0, 82.0% identity in 222 aa overlap. Similar to many bacterial hypo [...]
hisS protein networkhttps://string-db.org/network/272631.gene:17574315histidyl-tRNA synthase; Similar to M. tuberculosis hisS, Rv2580c, histidyl-tRNA synthase, SW:SYH_MYCTU (Q50641) (423 aa); Fasta score E(): 0, 85.9% identity in 417 aa overlap. Similar to many e.g [...]
aspS protein networkhttps://string-db.org/network/272631.gene:17574322aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: [...]
ML0508 protein networkhttps://string-db.org/network/272631.gene:17574329Similar to M. tuberculosis Rv2569c, conserved hypothetical protein, SW:YP69_MYCTU (Q50652) (314 aa); Fasta score E(): 0, 84.4% identity in 301 aa overlap and to other hypothetical proteins from M [...]
ML0510 protein networkhttps://string-db.org/network/272631.gene:17574331Similar to M. tuberculosis Rv2559c, conserved hypothetical protein, SW:YP59_MYCT (Q50739) (452 aa); Fasta score E(): 0, 83.4% identity in 452 aa overlapU. Similar to many hypothetical proteins in [...]
alaS protein networkhttps://string-db.org/network/272631.gene:17574333alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
ML0513 protein networkhttps://string-db.org/network/272631.gene:17574334Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.
ML0514 protein networkhttps://string-db.org/network/272631.gene:17574335Putative membrane protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG fami [...]
aroE protein networkhttps://string-db.org/network/272631.gene:17574336Similar to M. tuberculosis aroE, Rv2552c, shikimate 5-dehydrogenase, TR:P95001 (EMBL:AL123456) (269 aa); Fasta score E(): 0, 81.5% identity in 270 aa overlap. Similar to many e.g. Neisseria menin [...]
aroF protein networkhttps://string-db.org/network/272631.gene:17574337Putative chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the br [...]
aroK protein networkhttps://string-db.org/network/272631.gene:17574338Putative shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
aroB protein networkhttps://string-db.org/network/272631.gene:17574339Putative 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. De [...]
aroD protein networkhttps://string-db.org/network/272631.gene:175743403-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
ML0520 protein networkhttps://string-db.org/network/272631.gene:17574341Putative membrane protein; Similar to M. tuberculosis Rv2536, possible membrane protein, TR:P95017 (EMBL:AL123456) (230 aa); Fasta score E(): 0, 63.2% identity in 201 aa overlap. Contains hydroph [...]
pepQ protein networkhttps://string-db.org/network/272631.gene:17574342Putative cytoplasmic peptidase; Similar to M. tuberculosis pepQ, Rv2535c, putative cytoplasmic peptidase, TR:P95018 (EMBL:AL123456) (372 aa); Fasta score E(): 0, 83.0% identity in 376 aa overlap. [...]
efp protein networkhttps://string-db.org/network/272631.gene:17574343Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirect [...]
nusB protein networkhttps://string-db.org/network/272631.gene:17574344Putative transcription termination protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequ [...]
adi protein networkhttps://string-db.org/network/272631.gene:17574345Putative amino acid decarboxylase; Similar to M. tuberculosis adi, Rv2531c, putative ornithine/arginine decarboxylase, TR:P95022 (EMBL:AL123456) (947 aa); Fasta score E(): 0, 86.4% identity in 95 [...]
ML0525 protein networkhttps://string-db.org/network/272631.gene:17574346Conserved hypothetical protein; Unknown function. Similar to M. tuberculosis Rv2493, hypothetical protein, TR:O53218 (EMBL:AL123456) (73 aa); Fasta score E(): 0.059, 47.7% identity in 44 aa overl [...]
pyrB protein networkhttps://string-db.org/network/272631.gene:17574353Similar to M. tuberculosis pyrB, Rv1380, aspartate carbamoyltransferase, SW:PYRB_MYCTU (P71808) (319 aa); Fasta score E(): 0, 89.9% identity in 318 aa overlap. Similar to many e.g. Pseudomonas pu [...]
pyrC protein networkhttps://string-db.org/network/272631.gene:17574354Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subf [...]
carA protein networkhttps://string-db.org/network/272631.gene:17574356Similar to M. tuberculosis carA, Rv1383, carbamoyl-phosphate synthase subunit, TR:P71811 (EMBL:AL123456) (376 aa); Fasta score E(): 0, 85.4% identity in 377 aa overlap. Similar to many e.g. Esche [...]
carB protein networkhttps://string-db.org/network/272631.gene:17574357Similar to M. tuberculosis carB, Rv1384, carbamoyl-phosphate synthase subunit. Similar to many e.g. Escherichia coli carB, carbamoyl-phosphate synthase subunit, SW:CARB_ECOLI (P00968) (1072 aa); [...]
pyrF protein networkhttps://string-db.org/network/272631.gene:17574358Similar to M. tuberculosis pyrF, Rv1385, orotidine 5'-phosphate decarboxylase, SW:DCOP_MYCTU (P77898) (274 aa); Fasta score E(): 0, 77.3% identity in 282 aa overlap. Similar to many e.g. Mycobact [...]
PE protein networkhttps://string-db.org/network/272631.gene:17574359PE-family protein; Similar to M. tuberculosis PE, Rv1386, PE-family protein, SW:YD86_MYCTU (P71656) (102 aa); Fasta score E(): 2.8e-25, 72.5% identity in 102 aa overlap; Similar to ML452, ML1183 [...]
PPE protein networkhttps://string-db.org/network/272631.gene:17574360PPE-family protein; Similar to M. tuberculosis PPE, Rv1387, PPE-family protein, TR:P71657 (EMBL:AL123456) (539 aa); Fasta score E(): 0, 69.5% identity in 544 aa overlap. Contains Pfam match to en [...]
mihF protein networkhttps://string-db.org/network/272631.gene:17574361Putative integration host factor; Similar to M. tuberculosis mihF, Rv1388, possible integration host factor, TR:P71658 (EMBL:AL123456) (190 aa); Fasta score E(): 0, 98.1% identity in 105 aa overl [...]
gmk protein networkhttps://string-db.org/network/272631.gene:17574362Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
ML0542 protein networkhttps://string-db.org/network/272631.gene:17574363Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits [...]
dfp protein networkhttps://string-db.org/network/272631.gene:17574364Putative flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the lat [...]
metK protein networkhttps://string-db.org/network/272631.gene:17574365Putative S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMe [...]
priA protein networkhttps://string-db.org/network/272631.gene:17574369Putative primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, [...]
ML0550 protein networkhttps://string-db.org/network/272631.gene:17574371Similar to M. tuberculosis Rv1404, putative marR-family transcriptional regulator, TR:P71672 (EMBL:AL123456) (160 aa); Fasta score E(): 0, 79.1% identity in 158 aa overlap. Shows weak similarity [...]
ML0551 protein networkhttps://string-db.org/network/272631.gene:17574372Putative methyltransferase; Similar to M. tuberculosis Rv1405c, hypothetical protein, SW:YE05_MYCTU (P71673) (274 aa); Fasta score E(): 0, 78.0% identity in 273 aa overlap. Shows weak similarity [...]
fmt protein networkhttps://string-db.org/network/272631.gene:17574373Putative methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-fo [...]
rpe protein networkhttps://string-db.org/network/272631.gene:17574375Putatibe ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
ribG protein networkhttps://string-db.org/network/272631.gene:17574376Putative bifunctional riboflavin-specific deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- [...]
ML0556 protein networkhttps://string-db.org/network/272631.gene:17574377Putative integral membrane drug transport protein; In association with lipoprotein LprG probably transports triacylglycerides (TAG) across the inner cell membrane into the periplasm; TAG probably [...]
lprG protein networkhttps://string-db.org/network/272631.gene:17574378Putative lipoprotein; Probably helps membrane protein ML0556 (P55) transport triacylglycerides (TAG) across the inner cell membrane into the periplasm and probably ultimately to the outer membran [...]
ribC protein networkhttps://string-db.org/network/272631.gene:17574379Similar to M. tuberculosis ribC, Rv1412, riboflavin synthase [alpha] chain, SW:RISA_MYCTU (P71680) (201 aa); Fasta score E(): 0, 82.4% identity in 199 aa overlap. Similar to many e.g. Bacillus su [...]
ribA protein networkhttps://string-db.org/network/272631.gene:17574380Putative GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-term [...]
ribH protein networkhttps://string-db.org/network/272631.gene:175743816,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. [...]
ML0561 protein networkhttps://string-db.org/network/272631.gene:17574382Putative membrane protein; Similar to M. tuberculosis Rv1417, hypothetical protein, SW:YE17_MYCTU (P71686) (154 aa); Fasta score E(): 0, 75.5% identity in 143 aa overlap. Similar to other hypothe [...]
uvrC protein networkhttps://string-db.org/network/272631.gene:17574383Putative excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is [...]
ML0563 protein networkhttps://string-db.org/network/272631.gene:17574384Conserved hypothetical protein; Displays ATPase and GTPase activities.
ML0564 protein networkhttps://string-db.org/network/272631.gene:17574385Conserved hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
ML0565 protein networkhttps://string-db.org/network/272631.gene:17574386Putative transcriptional regulator; Involved in cell division and chromosome segregation.
ML0569 protein networkhttps://string-db.org/network/272631.gene:17574390Putative membrane protein; Similar to M. tuberculosis Rv1433, putative membrane protein, TR:O06825 (EMBL:AL123456) (271 aa); Fasta score E(): 0, 68.3% identity in 271 aa overlap. Shows weak simil [...]
gap protein networkhttps://string-db.org/network/272631.gene:17574391Glyceraldehyde 3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction [...]
pgk protein networkhttps://string-db.org/network/272631.gene:17574392Phosphoglycerate kinase; Similar to M. tuberculosis pgk, Rv1437, phosphoglycerate kinase, SW:PGK_MYCTU (O06821) (412 aa); Fasta score E(): 0, 80.6% identity in 412 aa overlap. Similar to many e.g [...]
tpi protein networkhttps://string-db.org/network/272631.gene:17574393Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
ML0573 protein networkhttps://string-db.org/network/272631.gene:17574394Hypothetical protein; Unknown function. Previously sequenced as TR:Q49684 (EMBL:U00013) (91 aa); Fasta score E(): 0, 98.9% identity in 91 aa overlap. Contains Pfam match to entry PF00121 TIM, Tri [...]
ML0574 protein networkhttps://string-db.org/network/272631.gene:17574395Hypothetical protein; Unknown function. Previously sequenced as TR:Q49680 (EMBL:U00013) (105 aa); Fasta score E(): 0, 99.0% identity in 105 aa overlap.
ML0575 protein networkhttps://string-db.org/network/272631.gene:17574396Hypothetical protein; Unknown function.
ML0576 protein networkhttps://string-db.org/network/272631.gene:17574397Hypothetical protein; Unknown function. Previously sequenced as TR:Q49681 (EMBL:U00013) (76 aa); Fasta score E(): 1.5e-31, 100.0% identity in 76 aa overlap.
ML0577 protein networkhttps://string-db.org/network/272631.gene:17574398Putative protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family.
ppc protein networkhttps://string-db.org/network/272631.gene:17574399Putative phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
pgl protein networkhttps://string-db.org/network/272631.gene:17574400Putative 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
ML0580 protein networkhttps://string-db.org/network/272631.gene:17574401Similar to M. tuberculosis Rv1446c, hypothetical protein, TR:O06813 (EMBL:AL123456) (303 aa); Fasta score E(): 0, 70.3% identity in 239 aa overlap. Similar to hypothetical proteins from Streptomy [...]
tal protein networkhttps://string-db.org/network/272631.gene:17574403Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
tkt protein networkhttps://string-db.org/network/272631.gene:17574404Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
ctaB protein networkhttps://string-db.org/network/272631.gene:17574405Putative protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group [...]
ML0587 protein networkhttps://string-db.org/network/272631.gene:17574408Putative membrane protein; Similar to M. tuberculosis Rv1456c, putative membrane protein, TR:O53148 (EMBL:AL123456) (310 aa); Fasta score E(): 0, 83.3% identity in 300 aa overlap. Similar to bact [...]
ML0588 protein networkhttps://string-db.org/network/272631.gene:17574409Hypothetical protein; Unknown function. Previously sequenced as TR:Q49686 (EMBL:U00013) (80 aa); Fasta score E(): 0, 98.8% identity in 80 aa overlap.
ML0589 protein networkhttps://string-db.org/network/272631.gene:17574410Putative membrane protein; Similar to M. tuberculosis Rv1457c, putative membrane protein, TR:O86349 (EMBL:AL123456) (261 aa); Fasta score E(): 0, 83.1% identity in 260 aa overlap. Similar to bact [...]
ML0590 protein networkhttps://string-db.org/network/272631.gene:17574411Similar to M. tuberculosis Rv1458c, ABC-transporter ATP-binding protein, TR:O53149 (EMBL:AL123456) (313 aa); Fasta score E(): 0, 88.0% identity in 308 aa overlap. Similar to many e.g. Rhizobium s [...]
ML0591 protein networkhttps://string-db.org/network/272631.gene:17574412Putative membrane protein; Similar to M. tuberculosis Rv1459c, conserved hypothetical protein, TR:O53150 (EMBL:AL123456) (591 aa); Fasta score E(): 0, 78.6% identity in 585 aa overlap and to Rv21 [...]
ML0592 protein networkhttps://string-db.org/network/272631.gene:17574413Putative DNA-binding protein; Similar to M. tuberculosis Rv1460, hypothetical protein, TR:O53151 (EMBL:AL123456) (278 aa); Fasta score E(): 0, 79.6% identity in 250 aa overlap. Similar to other b [...]
ML0593 protein networkhttps://string-db.org/network/272631.gene:17574414Similar to M. tuberculosis Rv1461, hypothetical protein, SW:YE61_MYCTU (O53152) (846 aa); Fasta score E(): 0, 54.3% identity in 920 aa overlap. N- and C-termini are similar to various bacterial h [...]
ML0594 protein networkhttps://string-db.org/network/272631.gene:17574415Similar to M. tuberculosis Rv1462, conserved hypothetical protein, SW:YE62_MYCTU (O53153) (397 aa); Fasta score E(): 0, 80.4% identity in 392 aa overlap. Similar to many bacterial hypothetical pr [...]
ML0595 protein networkhttps://string-db.org/network/272631.gene:17574416Similar to M. tuberculosis Rv1463, putative ABC transporter ATP-binding protein, TR:O53154 (EMBL:AL123456) (266 aa); Fasta score E(): 0, 85.8% identity in 267 aa overlap. Similar to many members [...]
ML0596 protein networkhttps://string-db.org/network/272631.gene:17574417Putative aminotransferase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
ML0597 protein networkhttps://string-db.org/network/272631.gene:17574418Similar to M. tuberculosis Rv1465, conserved hypothetical protein, TR:O53156 (EMBL:AL123456) (162 aa); Fasta score E(): 0, 79.4% identity in 165 aa overlap. Similar to many hypothetical proteins [...]
ML0598 protein networkhttps://string-db.org/network/272631.gene:17574419Similar to M. tuberculosis Rv1466, conserved hypothetical protein, TR:O53157 (EMBL:AL123456) (115 aa); Fasta score E(): 0, 82.6% identity in 115 aa overlap. Similar to hypothetical proteins locat [...]
ML0603 protein networkhttps://string-db.org/network/272631.gene:17574424Putative lipoprotein; Similar to M. tuberculosis Rv2413c, conserved hypothetical protein, TR:P71730 (EMBL:AL123456) (316 aa); Fasta score E(): 0, 83.5% identity in 316 aa overlap. Also similar to [...]
rpsT protein networkhttps://string-db.org/network/272631.gene:1757442530S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
ML0605 protein networkhttps://string-db.org/network/272631.gene:17574426Similar to M. tuberculosis Rv2411c, conserved hypothetical protein, SW:YO11_MYCTU (P71732) (551 aa); Fasta score E(): 0, 87.4% identity in 554 aa overlap. Similar to other bacterial hypothetical [...]
ML0606 protein networkhttps://string-db.org/network/272631.gene:17574427Similar to M. tuberculosis Rv2410c, conserved hypothetical protein, TR:P71733 (EMBL:AL123456) (325 aa); Fasta score E(): 0, 90.8% identity in 325 aa overlap. Similar to other bacterial hypothetic [...]
ML0607 protein networkhttps://string-db.org/network/272631.gene:17574428Similar to M. tuberculosis Rv2409c, conserved hypothetical protein, TR:P71734 (EMBL:AL123456) (279 aa); Fasta score E(): 0, 82.1% identity in 279 aa overlap and to Rv2569c, hypothetical protein, [...]
lepA protein networkhttps://string-db.org/network/272631.gene:17574432Putative GTP-binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one- [...]
ML0614 protein networkhttps://string-db.org/network/272631.gene:17574435Hypothetical protein; Unknown function. Previously sequenced as TR:Q49760 (EMBL:U00016) (95 aa); Fasta score E(): 0, 100.0% identity in 95 aa overlap.
subI protein networkhttps://string-db.org/network/272631.gene:17574436Putative sulphate-binding protein; Similar to M. tuberculosis subI, Rv2400c, putative sulphate binding protein, TR:P71744 (EMBL:AL123456) (356 aa); Fasta score E(): 0, 76.5% identity in 340 aa ov [...]
mtb12 protein networkhttps://string-db.org/network/272631.gene:17574441Putative secreted protein; Similar to M. tuberculosis mtb12, Rv2376c, low molecular weight antigen, SW:MB12_MYCTU (O05822) (168 aa); Fasta score E(): 0, 65.5% identity in 165 aa overlap. Previous [...]
hrcA protein networkhttps://string-db.org/network/272631.gene:17574445Putative heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
dnaJ2 protein networkhttps://string-db.org/network/272631.gene:17574446DnaJ homologue; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomo [...]
ML0626 protein networkhttps://string-db.org/network/272631.gene:17574447Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
phoH protein networkhttps://string-db.org/network/272631.gene:17574448phoH-family protein; Similar to M. tuberculosis phoH, Rv2372c, phoH-family protein, SW:PHOL_MYCTU (O05830) (352 aa); Fasta score E(): 0, 88.9% identity in 352 aa overlap. Similar to many hypothet [...]
ML0628 protein networkhttps://string-db.org/network/272631.gene:17574449Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
ML0630 protein networkhttps://string-db.org/network/272631.gene:17574451Similar to M. tuberculosis Rv2365c, hypothetical protein, TR:O05833 (EMBL:AL123456) (113 aa); Fasta score E(): 1.5e-22, 67.9% identity in 106 aa overlap. Similar to Streptomyces coelicolor SCC77. [...]
era protein networkhttps://string-db.org/network/272631.gene:17574452Putative Era-family GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis [...]
ML0633 protein networkhttps://string-db.org/network/272631.gene:17574454Conserved hypothetical protein; Involved in DNA repair and RecF pathway recombination.
ML0634 protein networkhttps://string-db.org/network/272631.gene:17574455Putative undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) in the cis configuration with (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP) [...]
uvrD2 protein networkhttps://string-db.org/network/272631.gene:17574459Putative ATP-dependent DNA helicase; DNA-dependent ATPase, stimulated equally by ss- and dsDNA. Has both ATPase and helicase activities (By similarity).
ML0638 protein networkhttps://string-db.org/network/272631.gene:17574460Putative secreted protein; Unknown function. Previously sequenced as TR:Q49769 (EMBL:U00016) (100 aa); Fasta score E(): 0, 99.0% identity in 100 aa overlap. Contains a possible N-terminal signal [...]
whiB7 protein networkhttps://string-db.org/network/272631.gene:17574461Putative transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
ML0640 protein networkhttps://string-db.org/network/272631.gene:17574462Conserved hypothetical protein; Similar to M. tuberculosis Rv3197, putative ABC transporter, TR:O53343 (EMBL:AL123456) (447 aa); Fasta score E(): 0, 83.0% identity in 447 aa overlap. Similar to m [...]
ML0642 protein networkhttps://string-db.org/network/272631.gene:17574464Similar to M. tuberculosis Rv3195, conserved hypothetical protein, TR:O53341 (EMBL:AL123456) (472 aa); Fasta score E(): 0, 79.2% identity in 475 aa overlap. Similar to Streptomyces coelicolor SCE [...]
ML0643 protein networkhttps://string-db.org/network/272631.gene:17574465Putative secreted protein; Similar to M. tuberculosis Rv3194c, conserved hypothetical protein, TR:O53340 (EMBL:AL123456) (340 aa); Fasta score E(): 0, 80.3% identity in 340 aa overlap. Similar to [...]
ML0644 protein networkhttps://string-db.org/network/272631.gene:17574466Similar to M. tuberculosis Rv3193c, putative integral membrane protein, TR:O53339 (EMBL:AL123456) (992 aa); Fasta score E(): 0, 86.1% identity in 989 aa overlap and to Rv0064, putative membrane p [...]
ML0659 protein networkhttps://string-db.org/network/272631.gene:17574482Hypothetical protein; Unknown function. Previously sequenced as TR:O32892 (EMBL:Z98271) (108 aa); Fasta score E(): 0, 100.0% identity in 108 aa overlap.
fadE23 protein networkhttps://string-db.org/network/272631.gene:17574483Putative acyl-CoA dehydrogenase; Similar to M. tuberculosis fadE23, Rv3140, acyl-CoA dehydrogenase, TR:P95186 (EMBL:AL123456) (401 aa); Fasta score E(): 0, 89.5% identity in 401 aa overlap. Simil [...]
fadE24 protein networkhttps://string-db.org/network/272631.gene:17574484Putative acyl-CoA dehydrogenase; Similar to M. tuberculosis fadE24, Rv3139, acyl-CoA dehydrogenase, TR:P95187 (EMBL:AL123456) (468 aa); Fasta score E(): 0, 83.6% identity in 464 aa overlap. Simil [...]
ML0662 protein networkhttps://string-db.org/network/272631.gene:17574485Similar to M. tuberculosis Rv3137, putative monophosphatase, TR:P95189 (EMBL:AL123456) (260 aa); Fasta score E(): 0, 81.8% identity in 253 aa overlap. Similar to putative N-amidino-scyllo-inosami [...]
ML0663 protein networkhttps://string-db.org/network/272631.gene:17574486Hypothetical protein; Unknown function. Previously sequenced as TR:O32888 (EMBL:Z98271) (104 aa); Fasta score E(): 0, 99.0% identity in 104 aa overlap.
ML0664 protein networkhttps://string-db.org/network/272631.gene:17574487Hypothetical protein; Unknown function.
fprA protein networkhttps://string-db.org/network/272631.gene:17574489Putative NADPH-ferredoxin reductase; May serve as electron transfer protein and supply electrons to P450 systems; Belongs to the ferredoxin--NADP reductase type 1 family.
prfB protein networkhttps://string-db.org/network/272631.gene:17574490Putative peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
ftsE protein networkhttps://string-db.org/network/272631.gene:17574492Putative cell division ATP-binding protein; Part of the ABC transporter FtsEX involved in cellular division.
ftsX protein networkhttps://string-db.org/network/272631.gene:17574493Putative membrane protein; Part of the ABC transporter FtsEX involved in cellular division.
smpB protein networkhttps://string-db.org/network/272631.gene:17574494Putative SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribo [...]
folD protein networkhttps://string-db.org/network/272631.gene:17574498Putative methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the h [...]
ML0675 protein networkhttps://string-db.org/network/272631.gene:17574499Similar to M. tuberculosis Rv3346c, conserved hypothetical protein, TR:O50384 (EMBL:AL123456) (97 aa); Fasta score E(): 1.2e-24, 77.9% identity in 95 aa overlap (EMBL:AL123456) (97 aa); Fasta sco [...]
ML0676 protein networkhttps://string-db.org/network/272631.gene:17574500Hypothetical protein; Similar to M. tuberculosis Rv3354, conserved hypothetical protein, TR:O50383 (EMBL:AL123456) (129 aa); Fasta score E(): 6.2e-24, 55.9% identity in 127 aa overlap and Rv1690, [...]
ML0678 protein networkhttps://string-db.org/network/272631.gene:17574502Hypothetical protein; Unknown function. Previously sequenced as TR:O32876 (EMBL:Z98271) (175 aa); Fasta score E(): 0, 99.4% identity in 175 aa overlap.
ML0679 protein networkhttps://string-db.org/network/272631.gene:17574503Hypothetical protein; Unknown function.
metA protein networkhttps://string-db.org/network/272631.gene:17574506Putative homoserine o-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
ML0685 protein networkhttps://string-db.org/network/272631.gene:17574509Putative hydrolase; Similar to M. tuberculosis Rv3337, conserved hypothetical protein, TR:O53387 (EMBL:AL123456) (82 aa); Fasta score E(): 2.8e-17, 74.3% identity in 70 aa overlap and Rv3338, con [...]
trpS protein networkhttps://string-db.org/network/272631.gene:17574510Tryptophanyl tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
ML0687 protein networkhttps://string-db.org/network/272631.gene:17574511Putative membrane protein; Similar to M. tuberculosis Rv3335c, conserved hypothetical protein, TR:O53385 (EMBL:AL123456) (289 aa); Fasta score E(): 0, 68.8% identity in 288 aa overlap. Similar to [...]
ML0691 protein networkhttps://string-db.org/network/272631.gene:17574515Putative D-alanyl-D-alanine carboxypeptidase; Similar to M. tuberculosis Rv3330, putative penicillin binding protein, TR:O53380 (EMBL:AL123456) (405 aa); Fasta score E(): 0, 77.2% identity in 416 [...]
sdhB protein networkhttps://string-db.org/network/272631.gene:17574520Similar to M. tuberculosis sdhB, Rv3319, succinate dehydrogenase subunit B, TR:O53371 (EMBL:AL123456) (263 aa); Fasta score E(): 0, 89.8% identity in 264 aa overlap. Similar to many e.g. Escheric [...]
sdhA protein networkhttps://string-db.org/network/272631.gene:17574521Similar to M. tuberculosis sdhA, Rv3318, succinate dehydrogenase subunit A, TR:O53370 (EMBL:AL123456) (590 aa); Fasta score E(): 0, 92.5% identity in 590 aa overlap. Similar to many e.g. Escheric [...]
sdhD protein networkhttps://string-db.org/network/272631.gene:17574522Similar to M. tuberculosis sdhD, Rv3317, putative membrane anchor of succinate dehydrogenase, TR:O53369 (EMBL:AL123456) (144 aa); Fasta score E(): 0, 85.2% identity in 142 aa overlap. Shows weak [...]
sdhC protein networkhttps://string-db.org/network/272631.gene:17574523Similar to M. tuberculosis sdhC, Rv3316, putative membrane anchor of succinate dehydrogenase, TR:O53368 (EMBL:AL123456) (112 aa); Fasta score E(): 0, 88.4% identity in 112 aa overlap. Similar to [...]
add protein networkhttps://string-db.org/network/272631.gene:17574524Putative adenosine deaminase; Similar to M. tuberculosis add, Rv3313c, probable adenosine deaminase, TR:O53365 (EMBL:AL123456) (365 aa); Fasta score E(): 0, 88.2% identity in 356 aa overlap. Simi [...]
ML0703 protein networkhttps://string-db.org/network/272631.gene:17574527Similar to M. tuberculosis Rv3311, conserved hypothetical protein, TR:O53362 (EMBL:AL123456) (420 aa); Fasta score E(): 0, 77.5% identity in 423 aa overlap.
pmmB protein networkhttps://string-db.org/network/272631.gene:17574530Putative phospho-sugar mutase; Similar to M. tuberculosis pmmB, putative phosphomannomutase, TR:O53360 (EMBL:AL123456) (534 aa); Fasta score E(): 0, 76.8% identity in 538 aa overlap. Similar to m [...]
deoD protein networkhttps://string-db.org/network/272631.gene:17574531Putative purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with th [...]
ML0711 protein networkhttps://string-db.org/network/272631.gene:17574535Similar to M. tuberculosis Rv3304, conserved hypothetical protein, TR:O53356 (EMBL:AL123456) (159 aa); Fasta score E(): 0, 91.8% identity in 159 aa overlap. Shows weak similarity to Azotobacter v [...]
glpD protein networkhttps://string-db.org/network/272631.gene:17574537Similar to M. tuberculosis glpD2, Rv3302c, glycerol-3-phosphate dehydrogenase, TR:O07168 (EMBL:AL123456) (585 aa); Fasta score E(): 0, 90.8% identity in 584 aa overlap. Similar to many e.g. Esche [...]
ML0717 protein networkhttps://string-db.org/network/272631.gene:17574541Similar to M. tuberculosis Rv3295, putative TetR-family transcriptional regulator, TR:P96900 (EMBL:AL123456) (221 aa); Fasta score E(): 0, 85.5% identity in 220 aa overlap. Similar to many putati [...]
bccA protein networkhttps://string-db.org/network/272631.gene:17574550Acetyl/propionyl CoA carboxylase [alpha] subunit; This protein carries two functions: biotin carboxyl carrier protein and biotin carboxyltransferase.
sseA protein networkhttps://string-db.org/network/272631.gene:17574552Similar to M. tuberculosis sseA, Rv3283, putative thiosulfate sulfurtransferase, SW:THT2_MYCTU (P96888) (297 aa); Fasta score E(): 0, 83.4% identity in 296 aa overlap. Similar to many e.g. Azotob [...]
ML0729 protein networkhttps://string-db.org/network/272631.gene:17574553Conserved hypothetical protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nuc [...]
ML0730 protein networkhttps://string-db.org/network/272631.gene:17574554ML0730 protein; Similar to Mycobacterium tuberculosis hypothetical 19.0 kda protein RV3281 OR MTCY71.21 TR:P96886 (EMBL:Z92771) fasta scores: E(): 2.4e-22, 69.0% id in 87 aa. Previously sequenced [...]
accD5 protein networkhttps://string-db.org/network/272631.gene:17574555Acetyl/propionyl CoA carboxylase [beta] subunit; Similar to Mycobacterium tuberculosis pccb PCCB OR RV3280 OR MTCY71.20 TR:P96885 (EMBL:Z92771) fasta scores: E(): 0, 88.7% id in 549 aa, and to Sa [...]
birA protein networkhttps://string-db.org/network/272631.gene:17574556Biotin apo-protein ligase; Similar to Mycobacterium tuberculosis birA OR RV3279C OR MTCY71.19C TR:P96884 (EMBL:Z92771) fasta scores: E(): 0, 71.2% id in 271 aa, and to Escherichia coli birA bifun [...]
ML0733 protein networkhttps://string-db.org/network/272631.gene:17574557Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 19.8 kda protein RV3278C OR MTCY71.18C TR:P96883 (EMBL:Z92771) fasta scores: E(): 0, 83.1% id in 172 aa. Previously s [...]
ML0734 protein networkhttps://string-db.org/network/272631.gene:17574558Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 30.1 kDa protein RV3277 OR MTCY71.17 TR:P96882 (EMBL:Z92771) fasta scores: E(): 0, 84.6% id in 228 aa. Previously seq [...]
purK protein networkhttps://string-db.org/network/272631.gene:17574559Phosphoribosylaminoimidazole carboxylase ATPase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) [...]
purE protein networkhttps://string-db.org/network/272631.gene:17574560Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
fadE25 protein networkhttps://string-db.org/network/272631.gene:17574561Putative acyl-CoA dehydrogenase; Similar to Mycobacterium tuberculosis RV3274C OR MTCY71.14C, putative acyl-CoA dehydrogenase, TR:P96879 (EMBL:Z92771) fasta scores: E(): 0, 92.0% id in 389 aa, an [...]
ctpC protein networkhttps://string-db.org/network/272631.gene:17574571Putative cation transport ATPase; High affinity, slow turnover Mn(2+) transporting ATPase.
ML0748 protein networkhttps://string-db.org/network/272631.gene:17574572Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 9.8 kDa protein irpA OR RV3269 OR MTCY71.09 TR:P96874 (EMBL:Z92771) fasta scores: E(): 5.5e-23, 73.6% id in 91 a [...]
ML0750 protein networkhttps://string-db.org/network/272631.gene:17574574Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 51.3 kDa protein RV3267 OR MTCY71.07 TR:P96872 (EMBL:Z92771) fasta scores: E(): 0, 78.9% id in 498 aa, and to My [...]
rmlD protein networkhttps://string-db.org/network/272631.gene:17574575Putative dTDP-rhamnose modification protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
wbbL protein networkhttps://string-db.org/network/272631.gene:17574576Similar to Mycobacterium tuberculosis putative dTDP-rhamnosyl transferase RV3265C OR MTCY71.05C TR:P96870 (EMBL:Z92771) fasta scores: E(): 0, 84.7% id in 301 aa, and to Mycobacterium smegmatis dT [...]
rmlA2 protein networkhttps://string-db.org/network/272631.gene:17574577Putative sugar-phosphate nucleotidyl transferase; Similar to Mycobacterium tuberculosis hypothetical protein RV3264C OR MTCY71.04C TR:P96869 (EMBL:Z92771) fasta scores: E(): 0, 86.9% id in 359 aa [...]
ML0755 protein networkhttps://string-db.org/network/272631.gene:17574579Hypothetical protein; Unknown function.
ML0756 protein networkhttps://string-db.org/network/272631.gene:17574580Probable DNA methylase; Similar to Mycobacterium tuberculosis putative DNA methylase RV3263 OR MTCY71.03 TR:P96868 (EMBL:Z92771) fasta scores: E(): 0, 81.9% id in 541 aa and to Escherichia coli m [...]
ML0757 protein networkhttps://string-db.org/network/272631.gene:17574581Hypothetical protein; Unknown function.
ML0758 protein networkhttps://string-db.org/network/272631.gene:17574582Putative oxidoreductase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy [...]
ML0759 protein networkhttps://string-db.org/network/272631.gene:17574583Conserved hypothetical protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) wit [...]
whiB2 protein networkhttps://string-db.org/network/272631.gene:17574584Putative transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
ML0761 protein networkhttps://string-db.org/network/272631.gene:17574585Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 15.6 kDa protein RV3259 OR MTV015.04 TR:O53352 (EMBL:AL021840) fasta scores: E(): 0, 89.2% id in 139 aa and to M [...]
ML0762 protein networkhttps://string-db.org/network/272631.gene:17574586Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 16.8 kDa protein RV3258C OR MTV015.03C TR:O53351 (EMBL:AL021840) fasta scores: E(): 0, 76.9% id in 169 aa, and t [...]
pmmA protein networkhttps://string-db.org/network/272631.gene:17574587Putative phosphomannomutase; Similar to Mycobacterium tuberculosis pmmA, RV3257C, putative phosphomannomutase, TR:O86374 (EMBL:Z95121) fasta scores: E(): 0, 83.1% id in 468 aa and to Escherichia [...]
ML0764 protein networkhttps://string-db.org/network/272631.gene:17574588Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 35.3 kDa protein RV3256C OR MTV015.01C-MTCY20B11.31C TR:O05899 (EMBL:Z95121) fasta scores: E(): 0, 75.3% id in 3 [...]
manA protein networkhttps://string-db.org/network/272631.gene:17574589Putative mannose-6-phosphate isomerase; Similar to Mycobacterium tuberculosis manA OR RV3255C OR MTCY20B11.30C, putative mannose-6-phosphate isomerase, TR:O05898 (EMBL:Z95121) fasta scores: E(): [...]
sahH protein networkhttps://string-db.org/network/272631.gene:17574595Putative S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
tmk protein networkhttps://string-db.org/network/272631.gene:17574596Putative thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
mtrA protein networkhttps://string-db.org/network/272631.gene:17574597Putative two-component response regulator; Member of the two-component regulatory system MtrA/MtrB.
mtrB protein networkhttps://string-db.org/network/272631.gene:17574598Putative two-component system sensor kinase; Member of the two-component regulatory system MtrA/MtrB. Seems to function as a membrane-associated protein kinase that phosphorylates MtrA in respons [...]
lpqB protein networkhttps://string-db.org/network/272631.gene:17574599Putative lipoprotein; Similar to Mycobacterium tuberculosis putative lipoprotein RV3244C OR MTCY20B11.19C TR:O05889 (EMBL:Z95121) fasta scores: E(): 0, 87.9% id in 579 aa, and to Streptomyces coe [...]
ML0776 protein networkhttps://string-db.org/network/272631.gene:17574600ML0776 protein; Similar to the N-terminal half of Mycobacterium tuberculosis hypothetical 22.5 kDa protein RV3242C OR MTCY20B11.17C TR:O05887 (EMBL:Z95121) fasta scores: E(): 6.8e-18, 78.1% id in [...]
ML0777 protein networkhttps://string-db.org/network/272631.gene:17574601Hypothetical protein; Unknown function.
ML0778 protein networkhttps://string-db.org/network/272631.gene:17574602Conserved hypothetical protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during [...]
secA protein networkhttps://string-db.org/network/272631.gene:17574603Putative preprotein translocase subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP [...]
ML0781 protein networkhttps://string-db.org/network/272631.gene:17574605Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 17.2 kDa protein RV3237C OR MTCY20B11.12C TR:O05882 (EMBL:Z95121) fasta scores: E(): 0, 80.6% id in 160 aa, to D [...]
ML0782 protein networkhttps://string-db.org/network/272631.gene:17574606Similar to Mycobacterium tuberculosis putative transmembrane transport protein RV3236C OR MTCY20B11.11C TR:O05881 (EMBL:Z95121) fasta scores: E(): 0, 81.8% id in 385 aa, and to Escherichia coli g [...]
ML0791 protein networkhttps://string-db.org/network/272631.gene:17574615Conserved hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May [...]
aroA protein networkhttps://string-db.org/network/272631.gene:17574616Putative 3-phosphoshikimate 1-carboxyvinyl transferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce e [...]
ML0793 protein networkhttps://string-db.org/network/272631.gene:17574617Putative bacteriophage protein; Similar to Mycobacterium tuberculosis hypothetical 27.6 kDa protein RV3226C OR MTCY20B11.01C TR:O05872 (EMBL:Z95121) fasta scores: E(): 0, 70.6% id in 252 aa, and [...]
ML0796 protein networkhttps://string-db.org/network/272631.gene:17574620Hypothetical protein; Similar to the N-termini of Mycobacterium tuberculosis putative response regulator RV0844C OR MTV043.37C TR:O53856 (EMBL:AL022004) fasta scores: E(): 0.2, 39.7% id in 63 aa [...]
ML0798 protein networkhttps://string-db.org/network/272631.gene:17574622Conserved hypothetical protein; Similar to Mycobacterium tuberculosis ATP/GTP binding protein Rv2787 or MTV002.52 TR:O33329 (EMBL:AL008967) fasta scores: E(): 0, 76.5% id in 587 aa and to other M [...]
ML0799 protein networkhttps://string-db.org/network/272631.gene:17574623Conserved hypothetical protein; Similar to Mycobacterium smegmatis hypothetical 19.1 kDa protein TR:Q9XCD9 (EMBL:AF144091) fasta scores: E(): 1e-15, 60.2% id in 93 aa and to other hypothetical pr [...]
ML0802 protein networkhttps://string-db.org/network/272631.gene:17574627Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 7.3 kDa protein Rv3221c or MTCY07d11.05 TR:O05845 (EMBL:Z95120) fasta scores: E(): 6.2e-19, 90.1% id in 71 aa an [...]
ML0803 protein networkhttps://string-db.org/network/272631.gene:17574628Putative two-component system sensor kinase; Similar to Mycobacterium tuberculosis hypothetical 54.0 kDa protein Rv3220c or MTCY07D11.06 TR:O05846 (EMBL:Z95120) fasta scores: E(): 0, 81.8% id in [...]
whiB1 protein networkhttps://string-db.org/network/272631.gene:17574629Putative transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
ML0806 protein networkhttps://string-db.org/network/272631.gene:17574631Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 14.3 kDa protein Rv3217c or MTCY07D11.09 TR:O05849 (EMBL:Z95120) fasta scores: E(): 0, 77.1% id in 140 aa. Contains h [...]
entC protein networkhttps://string-db.org/network/272631.gene:17574633Similar to Mycobacterium tuberculosis putative isochorismate synthase entC or Rv3215 or MTCY07D11.11c (372 aa) TR:O05851 (EMBL:Z95120) fasta scores: E(): 0, 73.5% id in 366 aa and to Bacillus sub [...]
ML0810 protein networkhttps://string-db.org/network/272631.gene:17574635Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 42.5 kDa protein Rv3212 or MTCY07D11.14c (407 aa) TR:O05854 (EMBL:Z95120) fasta scores: E(): 0, 79.9% id in 407 aa. C [...]
rhlE protein networkhttps://string-db.org/network/272631.gene:17574636Similar to Mycobacterium tuberculosis putative ATP-dependent RNA helicase Rv3211 or MTCY07D11.15c (407 aa) TR:O05855 (EMBL:Z95120) fasta scores: E(): 0, 74.8% id in 531 aa, and to Klebsiella pneu [...]
ML0813 protein networkhttps://string-db.org/network/272631.gene:17574638Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 19.1 kDa protein Rv3209 or MTCY07D11.17c (186 aa) TR:O05857 (EMBL:Z95120) fasta scores: E(): 8.5e-23, 58.4% id in 185 [...]
ML0814 protein networkhttps://string-db.org/network/272631.gene:17574639Conserved hypothetical protein; Unknown but equivalent to M.tuberculosis Rv3208c and similar to Streptomyces coelicolor hypothetical protein. FASTA scores: Rv3208c, E(): 3e-32, 82% identity in 82 [...]
ML0815 protein networkhttps://string-db.org/network/272631.gene:17574640Similar to Mycobacterium tuberculosis putative TetR-family transcriptional regulator Rv3208 or MTCY07D11.18c (228 aa) TR:O05858 (EMBL:Z95120) fasta scores: E(): 0, 82.4% id in 227 aa. Contains a [...]
ML0816 protein networkhttps://string-db.org/network/272631.gene:17574641Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 31.0 kDa protein Rv3207c or MTCY07D11.19 (285 aa) TR:O05859 (EMBL:Z95120) fasta scores: E(): 0, 80.6% id in 284 [...]
moeZ protein networkhttps://string-db.org/network/272631.gene:17574642Probably involved in molybdopterin biosynthesis; Similar to M. tuberculosis moeZ, Rv3206c, moeB homologue, TR:O05860 (EMBL:AL123456) (392 aa); Fasta score E(): 0, 86.4% identity in 391 aa overlap [...]
ML0818 protein networkhttps://string-db.org/network/272631.gene:17574643Similar to M. tuberculosis Rv3205c, hypothetical protein, TR:O05861 (EMBL:AL123456) (292 aa); Fasta score E(): 0, 87.3% identity in 291 aa overlap.
furB protein networkhttps://string-db.org/network/272631.gene:17574649Putative ferric uptake regulatory protein; Similar to Mycobacterium tuberculosis cosmid y27 fur or Rv2359 or MTCY27.21c TR:O05839 (EMBL:Z95208) (130 aa) fasta scores: E(): 0, 86.9% id in 130 aa, [...]
ML0825 protein networkhttps://string-db.org/network/272631.gene:17574650Similar to Mycobacterium tuberculosis putative transcriptional regulator Rv2358 or MTCY27.22c TR:O05840 (EMBL:Z95208) (135 aa) fasta scores: E(): 0, 72.9% id in 140 aa. Contains a probable helix- [...]
glyS protein networkhttps://string-db.org/network/272631.gene:17574651Putative glycyl-tRNA synthase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
dgt protein networkhttps://string-db.org/network/272631.gene:17574656Similar to Mycobacterium tuberculosis deoxyguanosinetriphosphate triphosphohydrolase dgt or Rv2344c or MTCY98.13c SW:DGTP_MYCTU (P95240) (431 aa) fasta scores: E(): 0, 83.8% id in 421 aa and to m [...]
dnaG protein networkhttps://string-db.org/network/272631.gene:17574658DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
ML0834 protein networkhttps://string-db.org/network/272631.gene:17574659Similar to Mycobacterium tuberculosis hypothetical protein Rv2342 or MTCY98.11 TR:P95238 (EMBL:Z83860) (85 aa) fasta scores: E(): 3e-21, 76.9% id in 78 aa and shows weak similarity to Streptomyce [...]
ML0837 protein networkhttps://string-db.org/network/272631.gene:17574663Hypothetical protein; Similar to part of Streptomyces coelicolor putative aldolase SCI8.29C TR:Q9RJ24 (EMBL:AL132644) (240 aa) fasta scores: E(): 0.001, 32.5% id in 120 aa.
cysE protein networkhttps://string-db.org/network/272631.gene:17574664Similar to Mycobacterium tuberculosis putative serine acetyltransferase cysE or Rv2335 or MTCY98.0031C TR:P95231 (EMBL:Z83860) (229 aa) fasta scores: E(): 0, 76.4% id in 229 aa, and to Bacillus s [...]
cysK protein networkhttps://string-db.org/network/272631.gene:17574665Putative cysteine synthase; Catalyzes the conversion of O-acetylserine (OAS) to cysteine through the elimination of acetate and addition of hydrogen sulfide.
ML0840 protein networkhttps://string-db.org/network/272631.gene:17574666Hypothetical protein; Unknown function. Previously sequenced as TR:O32977 (EMBL:Z98741).
ML0841 protein networkhttps://string-db.org/network/272631.gene:17574667Major membrane protein I; Similar to Mycobacterium paratuberculosis 35 kDa protein TR:Q9RAJ4 (EMBL:AJ250887) (307 aa) fasta scores: E(): 0, 92.2% id in 307 aa and to Mycobacterium avium major mem [...]
ML0842 protein networkhttps://string-db.org/network/272631.gene:17574668Conserved hypothetical protein; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
narK protein networkhttps://string-db.org/network/272631.gene:17574670Similar to Mycobacterium tuberculosis putative nitrite extrusion protein narK1 or Rv2329c or MTCY3G12.05 TR:P71883 (EMBL:Z79702) (515 aa) fasta scores: E(): 0, 69.3% id in 488 aa and to Escherich [...]
ML0845 protein networkhttps://string-db.org/network/272631.gene:17574671Hypothetical protein; Unknown function. Similar to part of some acyl-CoA oxidases e.g. Arabidopsis thaliana acyl-CoA oxidase cx2 TR:O65201 (EMBL:AF057043) (692 aa) fasta scores: E(): 1.5e-06, 35. [...]
ML0848 protein networkhttps://string-db.org/network/272631.gene:17574674ABC transporter; Similar to Mycobacterium tuberculosis hypothetical ABC transporter ATP-binding protein Rv2326c or MTCY3G12.08 SW:YN26_MYCTU (P71886) (697 aa) fasta scores: E(): 0, 76.9% id in 69 [...]
ML0849 protein networkhttps://string-db.org/network/272631.gene:17574675Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 30.0 kDa protein Rv2325c or MTCY3G12.09 SW:YN25_MYCTU (P71887) (282 aa) fasta scores: E(): 0, 77.3% id in 282 aa [...]
ribF protein networkhttps://string-db.org/network/272631.gene:17574678Putative riboflavin kinase; Similar to Mycobacterium tuberculosis riboflavin kinase ribF or Rv2786c or MTV002.51C TR:O33328 (EMBL:AL008967) (331 aa) fasta scores: E(): 0, 87.5% id in 327 aa and t [...]
rpsO protein networkhttps://string-db.org/network/272631.gene:1757467930S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging seve [...]
gpsI protein networkhttps://string-db.org/network/272631.gene:17574680Putative polyribonucleotide phosphorylase / guanosine pentaphosphate synthetase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in [...]
pepR protein networkhttps://string-db.org/network/272631.gene:17574681Putative zinc protease; EC_number=3.4.99.-; Similar to Mycobacterium tuberculosis hypothetical zinc protease Rv2782c or MTV002.47C SW:YR82_MYCTU (O33324) (438 aa) fasta scores: E(): 0, 84.3% id i [...]
ML0857 protein networkhttps://string-db.org/network/272631.gene:17574683Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 26.9 kDa protein Rv2219 or MTCY190.30 SW:YM19_MYCTU (Q10405) (250 aa) fasta scores: E(): 0, 80.8% id in 250 aa. Simil [...]
lipA protein networkhttps://string-db.org/network/272631.gene:17574684Putative lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependen [...]
lipB protein networkhttps://string-db.org/network/272631.gene:17574685Putative lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-A [...]
ML0860 protein networkhttps://string-db.org/network/272631.gene:17574686Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 31.7 kDa protein Rv2216 or MTCY190.27 SW:YM16_MYCTU (Q10403) (301 aa) fasta scores: E(): 0, 84.2% id in 297 aa. [...]
ML0861 protein networkhttps://string-db.org/network/272631.gene:17574687Putative dihydrolipoamide acyltransferase; Similar to Mycobacterium tuberculosis dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex sucB or Rv2215 or MTCY190.2 [...]
ephD protein networkhttps://string-db.org/network/272631.gene:17574688Putative oxidoreductase; Similar to Mycobacterium tuberculosis probable oxidoreductase ephD or Rv2214c or MTCY190.25C SW:EPHD_MYCTU (Q10402) (592 aa) fasta scores: E(): 0, 80.4% id in 596 aa. Sim [...]
ML0863 protein networkhttps://string-db.org/network/272631.gene:17574689Hypothetical protein; Unknown function. Previously sequenced as TR:O32957 (EMBL:Z98741).
pepA protein networkhttps://string-db.org/network/272631.gene:17574690Putative aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides [...]
gcvT protein networkhttps://string-db.org/network/272631.gene:17574691Putative aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
ilvE protein networkhttps://string-db.org/network/272631.gene:17574692Putative branched-chain-amino-acid transaminase; Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
cobT protein networkhttps://string-db.org/network/272631.gene:17574694Putative nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzim [...]
ML0869 protein networkhttps://string-db.org/network/272631.gene:17574695Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 14.0 kDa protein Rv2206 or MTCY190.17 SW:YM06_MYCTU (Q10395) (124 aa) fasta scores: E(): 0, 76.6% id in 124 aa a [...]
ML0871 protein networkhttps://string-db.org/network/272631.gene:17574697Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 12.5 kDa protein Rv2204c or MTCY190.15C SW:YM04_MYCTU (Q10393) (118 aa) fasta scores: E(): 0, 92.4% id in 118 aa [...]
ML0872 protein networkhttps://string-db.org/network/272631.gene:17574698Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 24.4 kDa protein Rv2203 or MYCY190.14 SW:YM03_MYCTU (Q10392) (230 aa) fasta scores: E(): 0, 61.7% id in 230 aa. Conta [...]
ML0873 protein networkhttps://string-db.org/network/272631.gene:17574699Putative carbohydrate kinase; Similar to Mycobacterium tuberculosis hypothetical sugar kinase Rv2202c or MTCY190.13C SW:YM02_MYCTU (Q10391) (324 aa) fasta scores: E(): 0, 83.3% id in 324 aa, and [...]
asnB protein networkhttps://string-db.org/network/272631.gene:17574700Similar to Mycobacterium tuberculosis putative asparagine synthetase [glutamine-hydrolyzing] Rv2201 or mtcy190.12 SW:ASNH_MYCTU (Q10374) (652 aa) fasta scores: E(): 0, 83.3% id in 659 aa and to B [...]
ctaC protein networkhttps://string-db.org/network/272631.gene:17574701Putative cytochrome C oxidase chain II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binucle [...]
ML0876 protein networkhttps://string-db.org/network/272631.gene:17574702Putative membrane protein; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
mmpS3 protein networkhttps://string-db.org/network/272631.gene:17574703Putative membrane protein; Similar to Mycobacterium tuberculosis putative membrane protein mmpS3 or Rv2198c or MTCY190.09C SW:MMS3_MYCTU (Q10390) (299 aa) fasta scores: E(): 0, 69.8% id in 308 aa [...]
ML0878 protein networkhttps://string-db.org/network/272631.gene:17574704Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 15.7 kDa protein Rv0008c or MTCY10H4.07C SW:Y008_MYCTU (P71577) (214 aa) fasta scores: E(): 0, 62.6% id in 211 a [...]
qcrB protein networkhttps://string-db.org/network/272631.gene:17574705Putative cytochrome B; Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes [...]
qcrA protein networkhttps://string-db.org/network/272631.gene:17574706Putative Rieske iron-sulphur reductase component; Similar to Mycobacterium tuberculosis putative ubiquinol-cytochrome C reductase iron-sulfur subunit qcrA or Rv2195 or MTCY190.06 SW:QCRA_MYCTU (Q [...]
qcrC protein networkhttps://string-db.org/network/272631.gene:17574707Putative cytochrome C reductase cytochrome C component; Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP syn [...]
ctaE protein networkhttps://string-db.org/network/272631.gene:17574708Cytochrome C oxidase subunit III; Similar to Mycobacterium tuberculosis probable cytochrome C oxidase polypeptide III ctaE or Rv2193 or MTCY190.04 SW:COX3_MYCTU (Q10385) (203 aa) fasta scores: E( [...]
trpD protein networkhttps://string-db.org/network/272631.gene:17574709Putative anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-a [...]
ML0885 protein networkhttps://string-db.org/network/272631.gene:17574711Putative secreted protein; Similar to Mycobacterium tuberculosis putative secreted protein Rv2190c or MTCY190.01c or MTV021.23C SW:YL90_MYCTU (Q10383; O53524) (385 aa) fasta scores: E(): 0, 69.2% [...]
ML0886 protein networkhttps://string-db.org/network/272631.gene:17574712Possible glycosyl transferase; Previously sequenced Mycobacterium leprae hypothetical protein TR:O69579 (EMBL:AL022602) (384 aa); Fasta score E(): 0, 99.7% identity in 384 aa overlap(EMBL:AL02260 [...]
ML0887 protein networkhttps://string-db.org/network/272631.gene:17574713Putative long-chain-fatty-acid-CoA ligase; The C-terminus of the predicted product of this CDS is identical to the previously sequenced Mycobacterium leprae putative long-chain- fatty-acid-CoA li [...]
ML0888 protein networkhttps://string-db.org/network/272631.gene:17574714Conserved hypothetical protein; Previously sequenced Mycobacterium leprae hypothetical protein TR:O69576 (EMBL:AL022602) (135 aa); Fasta score E(): 0, 100.0% identity in 135 aa overlap(EMBL:AL022 [...]
ML0889 protein networkhttps://string-db.org/network/272631.gene:17574715Conserved hypothetical protein; Previously sequenced Mycobacterium leprae hypothetical protein TR:O53519 (EMBL:AL021957) (144 aa); Fasta score E(): 0, 84.7% identity in 144 aa overlap (EMBL:AL021 [...]
ML0890 protein networkhttps://string-db.org/network/272631.gene:17574716Possible membrane transport ATPase; Previously sequenced Mycobacterium leprae hypothetical protein TR:O69574 (EMBL:AL022602) (415 aa); Fasta score E(): 0, 99.8% identity in 415 aa overlap(EMBL:AL [...]
ML0891 protein networkhttps://string-db.org/network/272631.gene:17574717Conserved hypothetical protein; Previously sequenced Mycobacterium leprae hypothetical protein TR:O69573 (EMBL:AL022602) (130 aa); Fasta score E(): 0, 100.0% identity in 130 aa overlap. Also high [...]
ML0892 protein networkhttps://string-db.org/network/272631.gene:17574718Possible acyltransferase; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:O69572 (EMBL:AL022602) (244 aa); Fasta score E(): 0, 100.0% identity in 244 aa overlap [...]
ML0893 protein networkhttps://string-db.org/network/272631.gene:17574719Probable conserved integral membrane protein; Identical to the previously sequenced Mycobacterium leprae putative integral membrane protein TR:O69571 (EMBL:AL022602) (428 aa); Fasta score E(): 0, [...]
ML0895 protein networkhttps://string-db.org/network/272631.gene:17574721Conserved hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
aroG protein networkhttps://string-db.org/network/272631.gene:17574722Identical to the previously sequenced Mycobacterium leprae 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase TR:O69569 (EMBL:AL022602) (462 aa); Fasta score E(): 0, 100.0% identity in 462 aa o [...]
ML0897 protein networkhttps://string-db.org/network/272631.gene:17574723Serine-threonine protein kinase; Identical to the previously sequenced Mycobacterium leprae putative serine/threonine protein kinase TR:O69568 (EMBL:AL022602) (400 aa); Fasta score E(): 0, 99.8% [...]
ML0898 protein networkhttps://string-db.org/network/272631.gene:17574724Putative DNA-binding protein; Identical to the previously sequenced Mycobacterium leprae putative transcriptional regulator TR:O69567 (EMBL:AL022602) (134 aa); Fasta score E(): 0, 99.3% identity [...]
ML0899 protein networkhttps://string-db.org/network/272631.gene:17574725Probable integral-membrane protein; Identical to the previously sequenced Mycobacterium leprae putative integral membrane protein TR:O69566 (EMBL:AL022602) (505 aa); Fasta score E(): 0, 100.0% id [...]
ML0901 protein networkhttps://string-db.org/network/272631.gene:17574727Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:O69565 (EMBL:AL022602) (304 aa); Fasta score E(): 0, 99.7% identity in 304 aa ov [...]
ML0902 protein networkhttps://string-db.org/network/272631.gene:17574728Probable lipoprotein; Identical to the previously sequenced Mycobacterium leprae putative lipoprotein TR:O69564 (EMBL:AL022602) (239 aa); Fasta score E(): 0, 99.6% identity in 239 aa overlap(EMBL [...]
ML0903 protein networkhttps://string-db.org/network/272631.gene:17574729Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:O69563 (EMBL:AL022602) (210 aa); Fasta score E(): 0, 99.5% identity in 210 aa ov [...]
ML0904 protein networkhttps://string-db.org/network/272631.gene:17574730Probable membrane protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:O69562 (EMBL:AL022602) (134 aa); Fasta score E(): 0, 100.0% identity in 134 aa overla [...]
ML0905 protein networkhttps://string-db.org/network/272631.gene:17574731Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YL66_MYCLE (SW:O69561) (143 aa); Fasta score E(): 0, 99.3% identity in 143 aa ov [...]
ML0906 protein networkhttps://string-db.org/network/272631.gene:17574732Conserved hypothetical protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
ML0907 protein networkhttps://string-db.org/network/272631.gene:17574733Putative conserved membrane protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:O69559 (EMBL:AL022602) (377 aa); Fasta score E(): 0, 100.0% identity in 377 [...]
pbpB protein networkhttps://string-db.org/network/272631.gene:17574734Penicillin-binding protein 2; Identical to the previously sequenced Mycobacterium leprae penicillin binding protein 2 TR:O69558 (EMBL:AL022602) (675 aa); Fasta score E(): 0, 99.9% identity in 675 [...]
murE protein networkhttps://string-db.org/network/272631.gene:17574735UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UM [...]
murF protein networkhttps://string-db.org/network/272631.gene:17574736UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murei [...]
mraY protein networkhttps://string-db.org/network/272631.gene:17574737phospho-N-acetylmuramoyl- pentapeptidetransferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY su [...]
murD protein networkhttps://string-db.org/network/272631.gene:17574738UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF f [...]
ftsW protein networkhttps://string-db.org/network/272631.gene:17574739Putative cell division protein FtsW; Identical to the previously sequenced Mycobacterium leprae cell division protein, FtsW, TR:O69553 (EMBL:AL022602) (534 aa); Fasta score E(): 0, 99.8% identity [...]
murG protein networkhttps://string-db.org/network/272631.gene:17574740Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide [...]
murC protein networkhttps://string-db.org/network/272631.gene:17574741UDP-N-acetyl-muramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
ML0916 protein networkhttps://string-db.org/network/272631.gene:17574742Putative FtsQ-family protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
ftsZ protein networkhttps://string-db.org/network/272631.gene:17574743Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing a [...]
ML0918 protein networkhttps://string-db.org/network/272631.gene:17574744Conserved hypothetical protein; Multicopper oxidase with polyphenol oxidase activity.
ML0919 protein networkhttps://string-db.org/network/272631.gene:17574745Possible DNA-binding protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
ML0920 protein networkhttps://string-db.org/network/272631.gene:17574746Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of F [...]
ML0921 protein networkhttps://string-db.org/network/272631.gene:17574747Possible membrane protein; Similar to several proteins of unknown function e.g. Mycobacterium tuberculosis TR:O06230 (EMBL:Z95388) (96 aa); Fasta score E(): 2.8e-32, 88.5% identity in 96 aa overl [...]
ag84 protein networkhttps://string-db.org/network/272631.gene:17574748Immunogenic protein, antigen 84; Important for maintaining cell shape and cell wall integrity by localizing peptidoglycan synthesis to the cell poles; Belongs to the DivIVA family.
ML0923 protein networkhttps://string-db.org/network/272631.gene:17574749Possible membrane protein; Highly similar to Mycobacterium tuberculosis hypothetical protein TR:O06231 (EMBL:Z95388) (118 aa); Fasta score E(): 1.3e-12, 50.4% identity in 129 aa overlap. Contains [...]
glnA protein networkhttps://string-db.org/network/272631.gene:17574751Highly similar to many glutamine synthetases (EC 6.3.1.2) including examples from: Mycobacterium tuberculosis SW:GLN1_MYCTU (Q10377) (478 aa); Fasta score E(): 0, 91.8% identity in 478 aa overlap [...]
ML0926 protein networkhttps://string-db.org/network/272631.gene:17574752Hypothetical protein; Weakly similar, in parts, to Mycobacterium tuberculosis SW:Y940_MYCTU (P71569) (288 aa); Fasta score E(): 0.0071, 30.4% identity in 112 aa overlap.
ML0927 protein networkhttps://string-db.org/network/272631.gene:17574753Hypothetical protein.
ML0938 protein networkhttps://string-db.org/network/272631.gene:17574764Hypothetical protein.
ML0939 protein networkhttps://string-db.org/network/272631.gene:17574765Hypothetical protein.
ML0949 protein networkhttps://string-db.org/network/272631.gene:17574775Hypothetical protein; Unknown function.
ML0950 protein networkhttps://string-db.org/network/272631.gene:17574776Hypothetical protein; Unknown function.
ML0953 protein networkhttps://string-db.org/network/272631.gene:17574779Hypothetical protein; Unknown function.
ppdK protein networkhttps://string-db.org/network/272631.gene:17574781Pyruvate, phosphate dikinase; Identical to the previously sequenced Mycobacterium leprae pyruvate, phosphate dikinase TR:O05566 (EMBL:Z94723) (601 aa); Fasta score E(): 0, 99.8% identity in 601 a [...]
ML0956 protein networkhttps://string-db.org/network/272631.gene:17574782Putative integral membrane protein; Almost identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:O05565 (EMBL:Z94723) (214 aa); Fasta score E(): 0, 100.0% identity in [...]
ML0957 protein networkhttps://string-db.org/network/272631.gene:17574783Hypothetical protein; Unknown function.
ML0958 protein networkhttps://string-db.org/network/272631.gene:17574784Possible membrane protein which contains a potential membrane spanning hydrophobic domain.
ML0959 protein networkhttps://string-db.org/network/272631.gene:17574785Hypothetical protein; Unknown function.
metE protein networkhttps://string-db.org/network/272631.gene:175747875-methyltetrahydropteroyltriglutamate- homocysteinmethyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation.; Be [...]
ML0963 protein networkhttps://string-db.org/network/272631.gene:17574789Hypothetical protein; Unknown function.
ML0964 protein networkhttps://string-db.org/network/272631.gene:17574790Hypothetical protein; Unknown function.
ftsK protein networkhttps://string-db.org/network/272631.gene:17574803Cell division protein; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-term [...]
ML0978 protein networkhttps://string-db.org/network/272631.gene:17574804Putative acetyltransferase; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:O05559 (EMBL:Z94723) (180 aa); Fasta score E(): 0, 100.0% identity in 180 aa overlap [...]
ML0979 protein networkhttps://string-db.org/network/272631.gene:17574805CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Identical to the previously sequenced Mycobacterium leprae TR:Q49839 (EMBL:U00019) (193 aa); Fasta score E(): 0, 100.0% identit [...]
ML0984 protein networkhttps://string-db.org/network/272631.gene:17574810Conserved hypothetical protein; Almost identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49850 (EMBL:U00019) (178 aa); Fasta score E(): 0, 100.0% identity in 149 [...]
ML0985 protein networkhttps://string-db.org/network/272631.gene:17574811Possible glycosyltransferase; Identical to the previously sequenced Mycobacterium leprae possible glycosyl transferase TR:Q49841 (EMBL:Z94723) (392 aa); Fasta score E(): 0, 100.0% identity in 392 [...]
ML0986 protein networkhttps://string-db.org/network/272631.gene:17574812Conserved hypothetical protein; Highly similar to proteins of undefined function from Mycobacterium tuberculosis Rv2738c TR:O33281 (EMBL:AL008967) (68 aa); Fasta score E(): 7.9e-24, 85.1% identit [...]
recA protein networkhttps://string-db.org/network/272631.gene:17574813RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of hom [...]
recX protein networkhttps://string-db.org/network/272631.gene:17574814Putative regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family.
ML0989 protein networkhttps://string-db.org/network/272631.gene:17574815Conserved hypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at positi [...]
ML0990 protein networkhttps://string-db.org/network/272631.gene:17574816Possible conserved membrane protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49834 (EMBL:U00019) (209 aa); Fasta score E(): 0, 100.0% identity in 209 a [...]
ML0994 protein networkhttps://string-db.org/network/272631.gene:17574820Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49835 (EMBL:U00019) (232 aa); Fasta score E(): 0, 99.6% identity in 232 aa over [...]
miaA protein networkhttps://string-db.org/network/272631.gene:17574821tRNA [delta](2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to [...]
dapF protein networkhttps://string-db.org/network/272631.gene:17574822Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...]
ML0997 protein networkhttps://string-db.org/network/272631.gene:17574823Possible ATP/GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-l [...]
ML1001 protein networkhttps://string-db.org/network/272631.gene:17574827Hypothetical protein; Doubful CDS. Similar in the N-terminus to Mycobacterium tuberculosis TR:O33227 (EMBL:Z98209) (82 aa); Fasta score E(): 4.4e-05, 37.5% identity in 88 aa overlap.
ML1002 protein networkhttps://string-db.org/network/272631.gene:17574828Possible conserved membrane protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49837 (EMBL:U00019) (687 aa); Fasta score E(): 0, 99.9% identity in 687 aa [...]
lexA protein networkhttps://string-db.org/network/272631.gene:17574829LexA, SOS repressor protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts wit [...]
ML1004 protein networkhttps://string-db.org/network/272631.gene:17574830Possible conserved membrane protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49846 (EMBL:U00019) (164 aa); Fasta score E(): 0, 100.0% identity in 164 a [...]
ML1005 protein networkhttps://string-db.org/network/272631.gene:17574831Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
ML1006 protein networkhttps://string-db.org/network/272631.gene:17574832Conserved hypothetical protein; May play a role in the intracellular transport of hydrophobic ligands.
ML1009 protein networkhttps://string-db.org/network/272631.gene:17574835Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49847 (EMBL:U00019) (326 aa); Fasta score E(): 0, 100.0% identity in 326 aa ove [...]
ML1010 protein networkhttps://string-db.org/network/272631.gene:17574836Hypothetical protein; Function unknown.
ML1011 protein networkhttps://string-db.org/network/272631.gene:17574837Hypothetical protein; Function unknown.
ML1013 protein networkhttps://string-db.org/network/272631.gene:17574839Iron dependent repressor; Metal-dependent DNA-binding protein that controls transcription of many genes involved in iron metabolism.
ML1014 protein networkhttps://string-db.org/network/272631.gene:17574840RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
ML1015 protein networkhttps://string-db.org/network/272631.gene:17574841Possible conserved membrane protein; Almost identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49983 (EMBL:U15181) (162 aa); Fasta score E(): 0, 100.0% identity i [...]
ML1016 protein networkhttps://string-db.org/network/272631.gene:17574842Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae TR:Q49984 (EMBL:U15181) (107 aa); Fasta score E(): 0, 99.1% identity in 107 aa overlap. Also highly simi [...]
ML1017 protein networkhttps://string-db.org/network/272631.gene:17574843Possible conserved integral membrane protein; Identical to the previously sequenced Mycobacterium leprae TR:Q49985 (EMBL:U15181) (330 aa); Fasta score E(): 0, 100.0% identity in 330 aa overlap. A [...]
ML1018 protein networkhttps://string-db.org/network/272631.gene:17574844Hypothetical protein; Unknown function.
rpoT protein networkhttps://string-db.org/network/272631.gene:17574848RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primar [...]
ppgK protein networkhttps://string-db.org/network/272631.gene:17574849Polyphosphate glucokinase; Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor.
suhB protein networkhttps://string-db.org/network/272631.gene:17574850Putative inositol monophosphatase; Identical to the previously sequenced Mycobacterium leprae extragenic suppressor protein SuhB homologue SW:SUHB_MYCLE (P46813) (291 aa); Fasta score E(): 0, 99. [...]
ML1025 protein networkhttps://string-db.org/network/272631.gene:17574851Possible secreted protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49989 (EMBL:U15181) (216 aa); Fasta score E(): 0, 99.5% identity in 216 aa overlap. [...]
ML1026 protein networkhttps://string-db.org/network/272631.gene:17574852Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q4998. Also highly similar to hypothetical proteins from Mycobacterium tuberculo [...]
ML1027 protein networkhttps://string-db.org/network/272631.gene:17574853Possible membrane protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49991 (EMBL:U15181) (157 aa); Fasta score E(): 0, 99.4% identity in 157 aa overlap. [...]
dut protein networkhttps://string-db.org/network/272631.gene:17574854Probable deoxyuridine triphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular conce [...]
ML1029 protein networkhttps://string-db.org/network/272631.gene:17574855Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49993 (EMBL:U15181) (273 aa); Fasta score E(): 0, 99.6% identity in 273 aa over [...]
ML1030 protein networkhttps://string-db.org/network/272631.gene:17574856Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49994 (EMBL:U15181) (232 aa); Fasta score E(): 0, 99.6% identity in 232 aa over [...]
ML1036 protein networkhttps://string-db.org/network/272631.gene:17574862Probable membrane transport protein; Identical to the previously sequenced Mycobacterium leprae probable membrane transport protein SW:AG45_MYCLE (P46838) (429 aa); Fasta score E(): 0, 99.8% iden [...]
ML1037 protein networkhttps://string-db.org/network/272631.gene:17574863Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49999 (EMBL:U15181) (184 aa); Fasta score E(): 0, 99.5% identity in 184 aa over [...]
dxs protein networkhttps://string-db.org/network/272631.gene:175748641-deoxy-D-xylulose 5-phosphate synthase (DXP synthase); Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose [...]
ML1040 protein networkhttps://string-db.org/network/272631.gene:17574866Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q50004 (EMBL:U15181) (429 aa); Fasta score E(): 0, 100.0% identity in 429 aa ove [...]
ML1041 protein networkhttps://string-db.org/network/272631.gene:17574867Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q50005 (EMBL:U15181) (196 aa); Fasta score E(): 0, 99.5% identity in 196 aa over [...]
hemE protein networkhttps://string-db.org/network/272631.gene:17574869Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
hemY protein networkhttps://string-db.org/network/272631.gene:17574870Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
ML1045 protein networkhttps://string-db.org/network/272631.gene:17574871Conserved hypothetical protein; Identical, apart from N-terminus, to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q50009 (EMBL:U15181) (297 aa); Fasta score E(): 0, 100.0 [...]
xclC protein networkhttps://string-db.org/network/272631.gene:17574877acyl-CoA synthase; Identical to the previously sequenced Mycobacterium leprae XclC TR:Q50017 (EMBL:U15181) (476 aa); Fasta score E(): 0, 99.8% identity in 476 aa overlap. Also highly similar to m [...]
ML1052 protein networkhttps://string-db.org/network/272631.gene:17574878Conserved hypothetical protein; Previously sequenced Mycobacterium leprae hypothetical protein TR:Q50018 (EMBL:U15181) (517 aa); Fasta score E(): 0, 100.0% identity in 421 aa overlap. Also highly [...]
ML1053 protein networkhttps://string-db.org/network/272631.gene:17574879Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49943 (EMBL:U15180) (99 aa); Fasta score E(): 0, 100.0% identity in 99 aa overl [...]
ML1055 protein networkhttps://string-db.org/network/272631.gene:17574881Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49945 (EMBL:U15180) (100 aa); Fasta score E(): 0, 100.0% identity in 100 aa ove [...]
ML1056 protein networkhttps://string-db.org/network/272631.gene:17574882Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49946 (EMBL:U15180) (95 aa); Fasta score E(): 0, 100.0% identity in 95 aa overl [...]
ML1057 protein networkhttps://string-db.org/network/272631.gene:17574883Hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49947 (EMBL:U15180) (117 aa); Fasta score E(): 0, 99.1% identity in 117 aa overlap.
ML1058 protein networkhttps://string-db.org/network/272631.gene:17574884Possible tranferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
dapE protein networkhttps://string-db.org/network/272631.gene:17574885Succinyl-diaminopimelate desuccinylase; Identical to the previously sequenced Mycobacterium leprae TR:Q49949 (EMBL:U15180) (400 aa); Fasta score E(): 0, 100.0% identity in 354 aa overlap. Also hi [...]
ML1061 protein networkhttps://string-db.org/network/272631.gene:17574887Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49952 (EMBL:U15180) (187 aa); Fasta score E(): 0, 100.0% identity in 187 aa ove [...]
folP2 protein networkhttps://string-db.org/network/272631.gene:17574889Dihydropteroate synthase; Has very low affinity for the DHPS substrate 6-hydroxymethyl- 7,8-dihydropterin-pyrophosphate, but can bind the inhibitor dapsone. Seems to lack dihydropteroate synthase [...]
ML1064 protein networkhttps://string-db.org/network/272631.gene:17574890Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49955 (EMBL:U15180) (318 aa); Fasta score E(): 0, 100.0% identity in 317 aa ove [...]
ML1065 protein networkhttps://string-db.org/network/272631.gene:17574891Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49955. Also highly similar to Mycobacterium tuberculosis hypothetical protein R [...]
tagA protein networkhttps://string-db.org/network/272631.gene:17574892DNA-3-methyladenine glycosidase I; Identical to the previously sequenced Mycobacterium leprae TR:Q49957 (EMBL:U15180) (192 aa); Fasta score E(): 0, 99.5% identity in 192 aa overlap. Also highly s [...]
ML1067 protein networkhttps://string-db.org/network/272631.gene:17574893Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49958 (EMBL:U15180) (75 aa); Fasta score E(): 1.9e-29, 100.0% identity in 75 aa [...]
glgC protein networkhttps://string-db.org/network/272631.gene:17574895Probable glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation re [...]
ML1070 protein networkhttps://string-db.org/network/272631.gene:17574896Putative TetR-family transcriptional regulator; Identical to the previously sequenced Mycobacterium leprae TR:Q49962 (EMBL:U15180) (217 aa); Fasta score E(): 0, 100.0% identity in 217 aa overlap. [...]
ML1075 protein networkhttps://string-db.org/network/272631.gene:17574901Probable O-methyltransferase; Previously sequenced Mycobacterium leprae TR:Q49969 (EMBL:U15180) (136 aa); Fasta score E(): 0, 100.0% identity in 136 aa overlap. Also highly similar to Mycobacteri [...]
sigE protein networkhttps://string-db.org/network/272631.gene:17574902ECF subfamily sigma subunit; Highly similar to many proposed ECF-family RNA-polymerase sigma factors including: Mycobacterium tuberculosis SigE TR:O06289 (EMBL:U87242) (257 aa); Fasta score E(): [...]
ML1077 protein networkhttps://string-db.org/network/272631.gene:17574903Conserved hypothetical protein; Highly similar to several proteins of undefined function e.g. from Mycobacterium avium TR:O05736 (EMBL:U87308) (133 aa); Fasta score E(): 0, 71.7% identity in 138 [...]
htrA protein networkhttps://string-db.org/network/272631.gene:17574904Possinble serine protease; Identical to the previously sequenced Mycobacterium leprae TR:Q49972 (EMBL:U15180) (533 aa); Fasta score E(): 0, 99.8% identity in 533 aa overlap. Also highly similar t [...]
ML1079 protein networkhttps://string-db.org/network/272631.gene:17574905Possible secreted protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide acro [...]
mrp protein networkhttps://string-db.org/network/272631.gene:17574906MRP-family ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; In the N-terminal section; belongs to the MIP18 family.
ML1086 protein networkhttps://string-db.org/network/272631.gene:17574912Probable solute-binding transport lipoprotein; Previously sequenced Mycobacterium leprae TR:Q49975 (EMBL:U15180) (469 aa); Fasta score E(): 0, 100.0% identity in 468 aa overlap. Also similar to m [...]
ML1087 protein networkhttps://string-db.org/network/272631.gene:17574913Probable ABC-transport protein, inner membrane component; Previously sequenced Mycobacterium leprae MalF TR:Q49976 (EMBL:U15180) (310 aa); Fasta score E(): 0, 100.0% identity in 304 aa overlap. A [...]
ML1088 protein networkhttps://string-db.org/network/272631.gene:17574914Probable ABC-transport protein, inner membrane component; Previously sequenced Mycobacterium leprae MalG TR:Q49977 (EMBL:U15180) (296 aa); Fasta score E(): 0, 100.0% identity in 287 aa overlap. A [...]
ML1089 protein networkhttps://string-db.org/network/272631.gene:17574915Probable ABC-transport protein, ATP-binding component; Identical to the previously sequenced Mycobacterium leprae TR:Q49978 (EMBL:U15180) (392 aa); Fasta score E(): 0, 100.0% identity in 392 aa o [...]
ML1090 protein networkhttps://string-db.org/network/272631.gene:17574916Probable membrane transport protein; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
mdh protein networkhttps://string-db.org/network/272631.gene:17574917Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
ML1093 protein networkhttps://string-db.org/network/272631.gene:17574919Lipoprotein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49982 (EMBL:U15180) (227 aa); Fasta score E(): 0, 100.0% identity in 227 aa overlap. Also highly s [...]
ML1094 protein networkhttps://string-db.org/network/272631.gene:17574920Short chain alcohol dehydrogenase; Highly similar to several Mycobacterium tuberculosis putative oxidoreductases e.g. Rv1245c TR:O50460 (EMBL:AL021006) (276 aa); Fasta score E(): 0, 78.3% identit [...]
odhA protein networkhttps://string-db.org/network/272631.gene:175749212-oxoglutarate dehydrogenase, E1 and E2 components; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading [...]
ML1096 protein networkhttps://string-db.org/network/272631.gene:17574922Putative membrane protein; Highly similar to Mycobacterium tuberculosis Rv1249c TR:O50464 (EMBL:AL021006) (262 aa); Fasta score E(): 0, 67.3% identity in 223 aa overlap. Contains multiple possibl [...]
ML1098 protein networkhttps://string-db.org/network/272631.gene:17574924Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein Rv1251c TR:O50466 (EMBL:AL021006) (1139 aa); Fasta score E(): 0, 75.5% identity in 1141 aa overla [...]
ML1099 protein networkhttps://string-db.org/network/272631.gene:17574925Putative lipoprotein; Highly similar to Mycobacterium tuberculosis putative lipoprotein SW:LPRE_MYCTU (Q11065) (202 aa); Fasta score E(): 0, 71.3% identity in 202 aa overlap. Contains a possible [...]
ML1101 protein networkhttps://string-db.org/network/272631.gene:17574927Similar to several acyltransferases including: Streptomyces thermotolerans macrolide antibiotics 3-O-acyltransferase TR:Q56074 (EMBLD30759:) (389 aa); Fasta score E(): 1.3e-14, 29.4% identity in [...]
ML1103 protein networkhttps://string-db.org/network/272631.gene:17574929Similar to many putative oxidoreductase subunits including: Escherichia coli glycolate oxidase subunit GlcD SW:GLCD_ECOLI (P52075) (499 aa); Fasta score E(): 0, 38.8% identity in 456 aa overlap a [...]
ML1105 protein networkhttps://string-db.org/network/272631.gene:17574931Conserved hypothetical protein; DNA glycosylase with broad substrate specificity.
ML1106 protein networkhttps://string-db.org/network/272631.gene:17574932Hypothetical protein; Unknown function.
ML1113 protein networkhttps://string-db.org/network/272631.gene:17574939Probable ABC transporter, ATP-binding component; Highly similar to many proposed ABC transporter proteins including: Mycobacterium tuberculosis Rv1272c SW:YC72_MYCTU (Q11047) (631 aa); Fasta scor [...]
ML1114 protein networkhttps://string-db.org/network/272631.gene:17574940Probable ABC transporter protein, ATP-binding component; Highly similar to many proposed ABC transporter proteins including: Mycobacterium tuberculosis Rv1273c SW:YC73_MYCTU (Q11046) (582 aa); Fa [...]
ML1115 protein networkhttps://string-db.org/network/272631.gene:17574941Possible lipoprotein; Highly similar to Mycobacterium tuberculosis possible lipoprotein Rv1274 SW:LPRB_MYCTU (Q11045) (185 aa); Fasta score E(): 0, 78.2% identity in 188 aa overlap. Contains a po [...]
ML1116 protein networkhttps://string-db.org/network/272631.gene:17574942Lipoprotein; Highly similar to Mycobacterium tuberculosis putative lipoprotein LrpC Rv1275 TR:O86337 (EMBL:Z77137) (180 aa); Fasta score E(): 0, 82.7% identity in 179 aa overlap. Contains a possi [...]
ML1117 protein networkhttps://string-db.org/network/272631.gene:17574943Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis Rv1276c SW:YC76_MYCTU (Q11043) (158 aa); Fasta score E(): 0, 65.4% identity in 162 aa overlap; Belongs to the SixA pho [...]
ML1119 protein networkhttps://string-db.org/network/272631.gene:17574945Hypothetical protein; Highly similar, in parts,to Mycobacterium tuberculosis hypothetical protein Rv1277 TR:Q50699 (EMBL:Z77137) (417 aa); Fasta score E(): 0, 82.0% identity in 383 aa overlap.
ML1120 protein networkhttps://string-db.org/network/272631.gene:17574946Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein Rv1278 SW:YC78_MYCTU (Q11042) (875 aa); Fasta score E(): 0, 69.5% identity in 872 aa overlap. Con [...]
ML1121 protein networkhttps://string-db.org/network/272631.gene:17574947Probable extracellular solute-binding dependent transport lipoprotein; Similar to several including: Mycobacterium tuberculosis extracellular solute-binding Rv1280c SW:YC80_MYCTU (Q11041) (591 aa [...]
ML1122 protein networkhttps://string-db.org/network/272631.gene:17574948Probable ABC transport protein, ATP-binding component; Highly similar to many putative ABC transport proteins e.g. Escherichia coli SW:YLIA_ECOLI (P75796) (269 aa); BlastP Expect 4.0e-28 Mycobact [...]
ML1123 protein networkhttps://string-db.org/network/272631.gene:17574949Probable binding-protein dependent transport protein; Highly similar to many membrane transport proteins e.g. Mycobacterium tuberculosis putative peptide transport permease Rv1282c SW:YC82_MYCTU [...]
ML1124 protein networkhttps://string-db.org/network/272631.gene:17574950Probable binding-protein dependent transport protein; Highly similar to many membrane transport proteins e.g. Mycobacterium tuberculosis putative peptide transport permease protein Rv1283c SW:YC8 [...]
argS protein networkhttps://string-db.org/network/272631.gene:17574954arginyl-tRNA synthase; Identical to the previously sequenced Mycobacterium leprae arginyl-tRNA synthetase (EC 6.1.1.19) (arginine--tRNA ligase) SW:SYR_MYCLE (P45840) (550 aa); Fasta score E(): 0, [...]
lysA protein networkhttps://string-db.org/network/272631.gene:17574955Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
hom protein networkhttps://string-db.org/network/272631.gene:17574956Homoserine dehydrogenase; Identical to the previously sequenced Mycobacterium leprae homoserine dehydrogenase (EC 1.1.1.3) SW:DHOM_MYCLE (P46806) (441 aa); Fasta score E(): 0, 99.8% identity in 4 [...]
thrC protein networkhttps://string-db.org/network/272631.gene:17574957Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
thrB protein networkhttps://string-db.org/network/272631.gene:17574958Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
rho protein networkhttps://string-db.org/network/272631.gene:17574959Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
rpmE protein networkhttps://string-db.org/network/272631.gene:1757496050S ribosomal protein L31; Binds the 23S rRNA.
prfA protein networkhttps://string-db.org/network/272631.gene:17574961Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
ML1135 protein networkhttps://string-db.org/network/272631.gene:17574962Possible protoporphyrinogen oxidase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs [...]
ML1136 protein networkhttps://string-db.org/network/272631.gene:17574963Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conve [...]
ML1137 protein networkhttps://string-db.org/network/272631.gene:17574964Possible glycosyltransferase; Involved in the biosynthesis of the disaccharide D-N- acetylglucosamine-L-rhamnose which plays an important role in the mycobacterial cell wall as a linker connectin [...]
ML1138 protein networkhttps://string-db.org/network/272631.gene:17574965Possible integral membrane protein; Identical to the previously sequenced Mycobacterium leprae SW:YD03_MYCLE (P53431) (153 aa); Fasta score E(): 0, 99.3% identity in 153 aa overlap. Also highly s [...]
atpB protein networkhttps://string-db.org/network/272631.gene:17574966Probable ATP synthase A chain protein; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
atpE protein networkhttps://string-db.org/network/272631.gene:17574967Probable ATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the ex [...]
atpF protein networkhttps://string-db.org/network/272631.gene:17574968Probable ATP synthase B chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the ex [...]
atpH protein networkhttps://string-db.org/network/272631.gene:17574969Bi-domained ATP synthase B, [Delta] chain protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F( [...]
atpA protein networkhttps://string-db.org/network/272631.gene:17574970ATP synthase [alpha] chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family [...]
atpG protein networkhttps://string-db.org/network/272631.gene:17574971ATP synthase [gamma] chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow [...]
atpD protein networkhttps://string-db.org/network/272631.gene:17574972ATP synthase [beta] chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alp [...]
atpC protein networkhttps://string-db.org/network/272631.gene:17574973ATP synthase [epsilon] chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.
ML1147 protein networkhttps://string-db.org/network/272631.gene:17574974Possible secreted protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD12_MYCLE (P53432) (147 aa); Fasta score E(): 0, 100.0% identity in 147 aa overlap. [...]
ML1148 protein networkhttps://string-db.org/network/272631.gene:17574975Doubtful CDS; Identical to the previously sequenced Mycobacterium leprae TR:Q50137 (EMBL:U15186) (51 aa); Fasta score E(): 4.9e-22, 100.0% identity in 51 aa overlap.
ML1149 protein networkhttps://string-db.org/network/272631.gene:17574976Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD14_MYCLE (P53523) (191 aa); Fasta score E(): 0, 100.0% identity in 191 aa over [...]
murA protein networkhttps://string-db.org/network/272631.gene:17574977UDP-N-acetylglucosamine-1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
ogt protein networkhttps://string-db.org/network/272631.gene:17574981Probable methylated-DNA-protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repa [...]
ML1155 protein networkhttps://string-db.org/network/272631.gene:17574985Conserved hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
ML1157 protein networkhttps://string-db.org/network/272631.gene:17574987Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae TR:Q49717 (EMBL:U00014) (155 aa); Fasta score E(): 0, 99.4% identity in 155 aa overlap. Also similar to [...]
fadA4 protein networkhttps://string-db.org/network/272631.gene:17574988Possible acetyl-CoA C-acetyltransferase; Identical to the previously sequenced Mycobacterium leprae probable acetyl-CoA acetyltransferase (EC 2.3.1.9) SW:THIL_MYCLE (P46707) (393 aa); Fasta score [...]
ML1159 protein networkhttps://string-db.org/network/272631.gene:17574989Conserved hypothetical protein; Previously sequenced Mycobacterium leprae TR:Q49716 (EMBL:U00014) (255 aa); Fasta score E(): 0, 100.0% identity in 217 aa overlap. Highly similar to Mycobacterium [...]
ML1165 protein networkhttps://string-db.org/network/272631.gene:17574995Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
ML1166 protein networkhttps://string-db.org/network/272631.gene:17574996Conserved hypothetical protein; Previously sequenced Mycobacterium leprae hypothetical protein SW:YD32_MYCLE (P53424) (222 aa); Fasta score E(): 0, 100.0% identity in 195 aa overlap. Also highly [...]
ML1167 protein networkhttps://string-db.org/network/272631.gene:17574997Possible hydrolase; Aminopeptidase; Belongs to the peptidase S58 family.
ML1171 protein networkhttps://string-db.org/network/272631.gene:17575001Possible conserved integral membrane protein; Previously sequenced Mycobacterium leprae hypothetical protein SW:YD37_MYCLE (P53426) (251 aa); Fasta score E(): 0, 100.0% identity in 238 aa overlap [...]
murI protein networkhttps://string-db.org/network/272631.gene:17575002Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
ML1173 protein networkhttps://string-db.org/network/272631.gene:17575003Conserved hypothetical protein; Previously sequenced Mycobacterium leprae hypothetical protein SW:YD39_MYCLE (P50474) (284 aa); Fasta score E(): 0, 100.0% identity in 260 aa overlap. Also highly [...]
rphA protein networkhttps://string-db.org/network/272631.gene:17575004Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucl [...]
ML1175 protein networkhttps://string-db.org/network/272631.gene:17575005Conserved hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine n [...]
ML1176 protein networkhttps://string-db.org/network/272631.gene:17575006Possible conserved membrane protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD42_MYCLE (P54133) (119 aa); Fasta score E(): 0, 100.0% identity in 119 aa [...]
ML1177 protein networkhttps://string-db.org/network/272631.gene:17575007Possible lipoprotein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YD43_MYCLE (P54134) (126 aa); Fasta score E(): 0, 99.2% identity in 126 aa overlap. Also h [...]
ML1180 protein networkhttps://string-db.org/network/272631.gene:17575011Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49946 (EMBL:U15180) (95 aa); Fasta score E(): 0, 100.0% identity in 95 aa overl [...]
ML1181 protein networkhttps://string-db.org/network/272631.gene:17575012Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49945 (EMBL:U15180) (100 aa); Fasta score E(): 0, 100.0% identity in 100 aa ove [...]
ML1182 protein networkhttps://string-db.org/network/272631.gene:17575013PPE-family protein; Identical to the previously sequenced Mycobacterium leprae putative PPE protein TR:Q9Z5K0 (EMBL:AL049191) (421 aa); Fasta score E(): 0, 100.0% identity in 421 aa overlap. Also [...]
ML1183 protein networkhttps://string-db.org/network/272631.gene:17575014Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49943 (EMBL:AL049191) (99 aa); Fasta score E(): 0, 100.0% identity in 99 aa ove [...]
ML1188 protein networkhttps://string-db.org/network/272631.gene:17575019Hypothetical protein; Unknown function.
ML1189 protein networkhttps://string-db.org/network/272631.gene:17575020Hypothetical protein; Unknown function, identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q9X7D8.
ML1190 protein networkhttps://string-db.org/network/272631.gene:17575021Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q9X7E1 (EMBL:AL049478) (239 aa); Fasta score E(): 0, 100.0% identity in 239 aa o [...]
fas protein networkhttps://string-db.org/network/272631.gene:17575022Fatty acid synthase; Identical to the previously sequenced Mycobacterium leprae putative type I fatty acid synthase TR:Q9X7E2 (EMBL:AL049478) (3076 aa); Fasta score E(): 0, 100.0% identity in 307 [...]
acpS protein networkhttps://string-db.org/network/272631.gene:17575023Holo-[acyl-carrier protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
ML1193 protein networkhttps://string-db.org/network/272631.gene:17575024Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q9X7E4 (EMBL:AL049478) (442 aa); Fasta score E(): 0, 100.0% identity in 442 aa o [...]
ileS protein networkhttps://string-db.org/network/272631.gene:17575026isoleucyl-tRNA synthase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such err [...]
ansA protein networkhttps://string-db.org/network/272631.gene:17575029L-asparaginase/L-glutaminase; Identical to the previously sequenced Mycobacterium leprae probable L-asparaginase (EC 3.5.1.1) SW:ASPG_MYCLE (Q9X7E6) (310 aa); Fasta score E(): 0, 100.0% identity [...]
lspA protein networkhttps://string-db.org/network/272631.gene:17575030Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
ML1200 protein networkhttps://string-db.org/network/272631.gene:17575031Putative pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
dnaE protein networkhttps://string-db.org/network/272631.gene:17575038DNA polymerase III, [alpha] subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' e [...]
ilvA protein networkhttps://string-db.org/network/272631.gene:17575040Threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production [...]
ML1213 protein networkhttps://string-db.org/network/272631.gene:17575044Conserved membrane protein; Previously sequenced Mycobacterium leprae putative membrane protein (fragment) TR:Q9X7F3 (EMBL:AL049478) (274 aa); Fasta score E(): 0, 100.0% identity in 274 aa overla [...]
ML1214 protein networkhttps://string-db.org/network/272631.gene:17575045Putative secreted p60-family protein; Previously sequenced Mycobacterium leprae TR:Q49634 (EMBL:U00010) (246 aa); Fasta score E(): 0, 100.0% identity in 206 aa overlap. This predicted product of [...]
bioA protein networkhttps://string-db.org/network/272631.gene:17575047Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8 [...]
bioF protein networkhttps://string-db.org/network/272631.gene:175750488-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and [...]
bioD protein networkhttps://string-db.org/network/272631.gene:17575049Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an urei [...]
bioB protein networkhttps://string-db.org/network/272631.gene:17575051Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily [...]
ML1221 protein networkhttps://string-db.org/network/272631.gene:17575052Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49616 (EMBL:U00010) (80 aa); Fasta score E(): 0, 98.8% identity in 80 aa overla [...]
ML1222 protein networkhttps://string-db.org/network/272631.gene:17575053Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49626 (EMBL:U00010) (198 aa); Fasta score E(): 0, 99.5% identity in 198 aa over [...]
ML1224 protein networkhttps://string-db.org/network/272631.gene:17575055Conserved hypothetical protein; Previously sequenced Mycobacterium leprae hypothetical protein TR:Q49628 (EMBL:U00010) (286 aa); Fasta score E(): 0, 100.0% identity in 233 aa overlap. Also highly [...]
nadA protein networkhttps://string-db.org/network/272631.gene:17575056Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
nadB protein networkhttps://string-db.org/network/272631.gene:17575057L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
nadC protein networkhttps://string-db.org/network/272631.gene:17575058Nicotinate-nucleotide pyrophosphatase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
pks3 protein networkhttps://string-db.org/network/272631.gene:17575060Mycocerosic acid synthase (polyketide synthase); Identical to many polyketide synthases involved in the biosynthesis of mycocerosyl lipids e.g. Mycobacterium tuberculosis probable mycocerosic aci [...]
papA3 protein networkhttps://string-db.org/network/272631.gene:17575061PKS-associated protein, unknown function; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49618 (EMBL:U00010) (471 aa); Fasta score E(): 0, 99.8% identity in 4 [...]
mmpL10 protein networkhttps://string-db.org/network/272631.gene:17575062Previously sequenced Mycobacterium leprae membrane protein MMPL10 SW:MMLA_MYCLE (Q49619) (1008 aa); Fasta score E(): 0, 100.0% identity in 983 aa overlap. Also highly similar to many MMPL-family [...]
ML1232 protein networkhttps://string-db.org/network/272631.gene:17575063Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49633 (EMBL:U00010) (391 aa); Fasta score E(): 0, 100.0% identity in 358 aa ove [...]
ML1233 protein networkhttps://string-db.org/network/272631.gene:17575064Conserved membrane protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49630 (EMBL:U00010) (230 aa); Fasta score E(): 0, 100.0% identity in 230 aa overlap [...]
ML1234 protein networkhttps://string-db.org/network/272631.gene:17575065Highly similar to acyl-CoA synthases from Mycobacterium tuberculosis Rv1185c TR:O50441 (EMBL:AL010186) (578 aa); Fasta score E(): 0, 72.4% identity in 579 aa overlap and Mycobacterium bovis TR:P7 [...]
ML1241 protein networkhttps://string-db.org/network/272631.gene:17575072Possible enoyl-CoA hydratase/isomerase; Could possibly oxidize fatty acids using specific components.
ML1243 protein networkhttps://string-db.org/network/272631.gene:17575075Hypothetical protein; Function unknown.
ML1244 protein networkhttps://string-db.org/network/272631.gene:17575076Conserved membrane protein; Highly similar to a family of Mycobacterium tuberculosis proteins e.g. Rv2484c SW:YO84_MYCTU (O53209) (491 aa); Fasta score E(): 0, 75.2% identity in 483 aa overlap. C [...]
ML1245 protein networkhttps://string-db.org/network/272631.gene:17575077Possible transferase; The N-terminus is similar to several phosphoserine phosphatases e.g. Haemophilus influenzae SW:SERB_HAEIN (P44997) (795 aa); BlastP Expect 9.8 and the C-terminus is similar [...]
plsB protein networkhttps://string-db.org/network/272631.gene:17575078Highly similar to many acyltransferases including: Escherichia coli glycerol-3-phosphate acyltransferase (EC 2.3.1.15) SW:PLSB_ECOLI (P00482) (806 aa); Fasta score E(): 1.5e-27, 24.4% identity in [...]
ML1248 protein networkhttps://string-db.org/network/272631.gene:17575080Highly similar to many proposed ABC-transporter ATP-binding proteins including:Escherichia coli SW: YJJK_ECOLI and Mycobacterium tuberculosis RV2477C TR:O53204 (EMBL:AL021246) (558 aa); Fasta sco [...]
ML1249 protein networkhttps://string-db.org/network/272631.gene:17575081Conserved hypothetical protein; Similar to several proteins of undefined function including: Mycobacterium tuberculosis RV2476C TR:O53203 (EMBL:AL021246) (1624 aa); Fasta score E(): 0, 81.5% iden [...]
glbO protein networkhttps://string-db.org/network/272631.gene:17575085Hemoglobin-like, oxygen carrier; Highly similar to putative globins from Mycobacterium tuberculosis RV2470 TR:O53197 (EMBL:AL021246) (128 aa); Fasta score E(): 0, 88.7% identity in 124 aa overlap [...]
ML1254 protein networkhttps://string-db.org/network/272631.gene:17575086Conserved hypothetical protein; Highly similar to several proteins of unknown function including: Mycobacterium tuberculosis RV2469C TR:O53196 (EMBL:AL021246) (222 aa); Fasta score E(): 0, 77.9% [...]
ML1255 protein networkhttps://string-db.org/network/272631.gene:17575087Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2468C TR:O53195 (EMBL:AL021246) (167 aa); Fasta score E(): 0, 81.2% identity in 165 aa overlap.
hisD protein networkhttps://string-db.org/network/272631.gene:17575089Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
hisC protein networkhttps://string-db.org/network/272631.gene:17575090Highly similar to many histidinol-phosphate aminotransferases (EC 2.6.1.9) involved in histidine biosynthesis e.g. Mycobacterium tuberculosis RV1600 TR:SW:HIS8_MYCTU (O06591) (380 aa); Fasta scor [...]
hisB protein networkhttps://string-db.org/network/272631.gene:17575091Highly similar to many imidazoleglycerol-phosphate dehydratases (EC 4.2.1.19) involved in histidine biosynthesis e.g. from Mycobacterium tuberculosis RV1601 SW:HIS7_MYCTU (O06590) (210 aa); Fasta [...]
hisH protein networkhttps://string-db.org/network/272631.gene:17575092Glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as pa [...]
hisA protein networkhttps://string-db.org/network/272631.gene:17575093Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family.
hisF protein networkhttps://string-db.org/network/272631.gene:17575095Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the amm [...]
hisI protein networkhttps://string-db.org/network/272631.gene:17575096phosphoribosyl-AMP 1,6 cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
ML1267 protein networkhttps://string-db.org/network/272631.gene:17575099Highly similar to many antiporters e.g. Mycobacterium tuberculosis RV1607 TR:O53910 (EMBL:AL022001) (360 aa); Fasta score E(): 0, 77.7% identity in 364 aa overlap and Escherichia coli SW:CHAA_ECO [...]
trpE protein networkhttps://string-db.org/network/272631.gene:17575101Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first [...]
ML1270 protein networkhttps://string-db.org/network/272631.gene:17575102Possible conserved membrane protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV1610 TR:O06128 (EMBL:Z95554) (235 aa); Fasta score E(): 0, 65.8% identity in 231 aa overla [...]
trpC protein networkhttps://string-db.org/network/272631.gene:17575103Highly similar to many indole-3-glycerol phosphate synthases (EC 4.1.1.48) involved in tryptophan biosynthesis e.g. Mycobacterium tuberculosis Rv1611 SW:TRPC_MYCTU (O06129) (272 aa); Fasta score [...]
trpB protein networkhttps://string-db.org/network/272631.gene:17575104Tryptophan synthase [beta] chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpA protein networkhttps://string-db.org/network/272631.gene:17575105Tryptophan synthase [alpha] chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
ML1274 protein networkhttps://string-db.org/network/272631.gene:17575106Possible prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipopro [...]
ML1275 protein networkhttps://string-db.org/network/272631.gene:17575107Hypothetical protein; Unknown function.
ML1276 protein networkhttps://string-db.org/network/272631.gene:17575108Conserved membrane protein; Similar to several proteins of undefined function including: Mycobacterium tuberculosis RV1616 TR:O06133 (EMBL:Z95554) (132 aa); Fasta score E(): 0, 68.5% identity in [...]
pykA protein networkhttps://string-db.org/network/272631.gene:17575109Pyruvate kinase; Highly similar to many pyruvate kinases (EC 2.7.1.40) including: Mycobacterium tuberculosis RV1617 SW:KPYK_MYCTU (O06134) (472 aa); Fasta score E(): 0, 90.7% identity in 472 aa o [...]
tesB protein networkhttps://string-db.org/network/272631.gene:17575110Highly similar to many acyl CoA thioesterases including: Escherichia coli SW:TESB_ECOLI (P23911) (285 aa); Fasta score E(): 5.6e-26, 32.1% identity in 287 aa overlap and Mycobacterium tuberculosi [...]
ML1286 protein networkhttps://string-db.org/network/272631.gene:17575119Possible two-component response regulatory protein; Similar to many proposed two-component response regulators including: Streptomyces coelicolor TR:Q9S2J0 (EMBL:AL109732) (218 aa); Fasta score E [...]
ML1288 protein networkhttps://string-db.org/network/272631.gene:17575122Possible peptidase; Similar to several members of the ARGE/DAPE/ACY1 protein family including: Mycobacterium tuberculosis DapE, RV2141C, TR:O06234 (EMBL:Z95388) (448 aa); Fasta score E(): 0, 83.9 [...]
ML1289 protein networkhttps://string-db.org/network/272631.gene:17575123Conserved hypothetical protein; Similar to many proteins of undefined function including: Mycobacterium tuberculosis Rv2140c SW:YL40_MYCTU (O06235) (176 aa); Fasta score E(): 0, 86.3% identity in [...]
pyrD protein networkhttps://string-db.org/network/272631.gene:17575127Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
ML1294 protein networkhttps://string-db.org/network/272631.gene:17575128Hypothetical protein; Unknown function.
ML1296 protein networkhttps://string-db.org/network/272631.gene:17575130Similar to Mycobacterium tuberculosis hypothetical protein RV2137C TR:O06238 (EMBL:Z95388) (137 aa); Fasta score E(): 1.3e-28, 75.5% identity in 106 aa overlap.
ML1297 protein networkhttps://string-db.org/network/272631.gene:17575131Possible undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
ML1298 protein networkhttps://string-db.org/network/272631.gene:17575132Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2135C TR:O06240 (EMBL:Z95388) (236 aa); Fasta score E(): 0, 75.2% identity in 250 aa overlap. A [...]
ML1299 protein networkhttps://string-db.org/network/272631.gene:17575133Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2134C TR:O06241 (EMBL:Z95388) (195 aa); Fasta score E(): 0, 91.1% identity in 192 aa overlap.
ML1300 protein networkhttps://string-db.org/network/272631.gene:17575134Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2133C TR:O06242 (EMBL:Z95388) (262 aa); Fasta score E(): 0, 79.4% identity in 262 aa overlap.
ML1301 protein networkhttps://string-db.org/network/272631.gene:17575135Possible inositol monophosphatase family protein; Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'- phosphate (PAP) and 3'-pho [...]
cysS2 protein networkhttps://string-db.org/network/272631.gene:17575136cysteinyl-tRNA synthase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
ansP1 protein networkhttps://string-db.org/network/272631.gene:17575138Probable L-asparagine permease; Highly similar to many L-asparagine transport proteins including: Salmonella typhimurium AnsP SW:ANSP_SALTY (P40812) (497 aa); Fasta score E(): 0, 58.7% identity i [...]
ansP2 protein networkhttps://string-db.org/network/272631.gene:17575139Probable L-asparagine permease; Highly similar to many L-asparagine transport proteins including: Salmonella typhimurium AnsP SW:ANSP_SALTY (P40812) (497 aa); Fasta score E(): 0, 58.9% identity i [...]
ML1306 protein networkhttps://string-db.org/network/272631.gene:17575140Conserved hypothetical protein; Similar to several proteins of unkown function including: Mycobacterium tuberculosis RV2125 TR:O33260 (EMBL:Z97559) (292 aa); Fasta score E(): 0, 85.0% identity in [...]
metH protein networkhttps://string-db.org/network/272631.gene:175751415-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subseq [...]
hisE protein networkhttps://string-db.org/network/272631.gene:17575143Highly similar to several phosphoribosyl-ATP pyrophosphatases (EC 3.6.1.31) involved in histidine biosynthesis, including: Sulfolobus solfataricus HisE SW:HIS2_SULSO (O33776) (94 aa); Fasta score [...]
hisG protein networkhttps://string-db.org/network/272631.gene:17575144ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate [...]
ML1312 protein networkhttps://string-db.org/network/272631.gene:17575146Conserved hypothetical protein; Highly similar to several proteins of unknown function e.g. Mycobacterium tuberculosis RV2119 TR:O33254 (EMBL:Z97559) (278 aa); Fasta score E(): 0, 79.9% identity [...]
ML1313 protein networkhttps://string-db.org/network/272631.gene:17575147Conserved hypothetical protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
ML1314 protein networkhttps://string-db.org/network/272631.gene:17575148Conserved hypothetical protein; Highly similar to several proteins of unknown function e.g. Mycobacterium tuberculosis RV2117 TR:O33252 (EMBL:Z97559) (97 aa); Fasta score E(): 0, 85.6% identity i [...]
ML1315 protein networkhttps://string-db.org/network/272631.gene:17575149Probable lipoprotein; Highly similar to Mycobacterium tuberculosis putative lipoprotein LppK (RV2116) SW:LPPK_MYCTU (O33251) (189 aa); Fasta score E(): 1.4e-29, 51.6% identity in 188 aa overlap. [...]
ML1316 protein networkhttps://string-db.org/network/272631.gene:17575150Probable AAA-family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essenti [...]
ML1320 protein networkhttps://string-db.org/network/272631.gene:17575154Conserved hypothetical protein; Highly similar to many proteins of undefined function including: Rhodococcus sp. TR:Q53081 (EMBL:U26422) (499 aa); Fasta score E(): 0, 83.5% identity in 502 aa ove [...]
ML1321 protein networkhttps://string-db.org/network/272631.gene:17575155Conserved hypothetical protein; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is te [...]
prcB protein networkhttps://string-db.org/network/272631.gene:17575156Proteasome [beta]-type subunit 2; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
prcA protein networkhttps://string-db.org/network/272631.gene:17575157Proteasome [alpha]-type subunit 1; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
ML1328 protein networkhttps://string-db.org/network/272631.gene:17575162Possible DNA-binding protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasoma [...]
ML1329 protein networkhttps://string-db.org/network/272631.gene:17575163Conserved hypothetical protein; Does not seem to be involved in pupylation or substrate degradation; Belongs to the PafB family.
ML1330 protein networkhttps://string-db.org/network/272631.gene:17575164Possible DNA-binding protein; Does not seem to be involved in pupylation or substrate degradation; Belongs to the PafC family.
ML1331 protein networkhttps://string-db.org/network/272631.gene:17575165Possible secreted protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide acro [...]
ML1332 protein networkhttps://string-db.org/network/272631.gene:17575166Membrane transport protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide acr [...]
helY protein networkhttps://string-db.org/network/272631.gene:17575167Probable helicase, Ski2 subfamily; Highly similar to many proposed Prokaryotic and Eukaryotic helicases including: Mycobacterium tuberculosis RV2092C SW:HELY_MYCTU (Q10701) (906 aa); Fasta score [...]
ML1334 protein networkhttps://string-db.org/network/272631.gene:17575168Possible conserved membrane protein; Highly similar to several e.g. Mycobacterium tuberculosis hypothetical protein RV2091C SW:YK91_MYCTU (Q10700) (244 aa); Fasta score E(): 0, 62.9% identity in [...]
ML1338 protein networkhttps://string-db.org/network/272631.gene:17575172Possible conserved integral membrane protein; Similar to several membrane proteins e.g. Mycobacterium tuberculosis RV2673 TR:P71970 (EMBL:Z80225) (433 aa); Fasta score E(): 0, 82.0% identity in 4 [...]
ML1339 protein networkhttps://string-db.org/network/272631.gene:17575173Putative secreted protease; Highly similar to several proteases including: Streptomyces lividans TR:Q54399 (EMBL:L42759) (513 aa); Fasta score E(): 2.7e-19, 25.7% identity in 548 aa overlap and M [...]
ML1340 protein networkhttps://string-db.org/network/272631.gene:17575174Possible reductase; Similar to several including: the C-terminal reductase domains of several riboflavin biosynthetic proteins e.g. Escherichia coli RibD SW:RIBD_ECOLI (X64395) (367 aa); Fasta sc [...]
ML1344 protein networkhttps://string-db.org/network/272631.gene:17575182Doubtful CDS; Unknown function, weakly similar, in parts, to several transposases e.g. Synechocystis sp. TR:Q55831 (EMBL:D64004) (259 aa); Fasta score E(): 2.6, 28.4% identity in 88 aa overlap.
ML1346 protein networkhttps://string-db.org/network/272631.gene:17575184Similar to many Prokaryotic and Eukaryotic long-chain acyl-CoA synthetases including: Mus musculus SW:VLCS_MOUSE (O35488) (620 aa); Fasta score E(): 1.5e-20, 24.7% identity in 570 aa overlap and [...]
ML1347 protein networkhttps://string-db.org/network/272631.gene:17575185Conserved hypothetical protein; Highly similar to proteins of unknown function from Mycobacterium tuberculosis RV1684 TR:O33186 (EMBL:Z98268) (74 aa); Fasta score E(): 6.9e-20, 70.1% identity in [...]
ML1351 protein networkhttps://string-db.org/network/272631.gene:17575189Similar to several DNA-3-methyladenine glycosylases from both Prokaryotes and Eukaryotes e.g. Bacillus subtilis SW:3MGH_BACSU (P94378) (196 aa); Fasta score E(): 7.7e-13, 38.4% identity in 185 aa [...]
tyrS protein networkhttps://string-db.org/network/272631.gene:17575190tyrosyl-tRNA synthase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tR [...]
ML1357 protein networkhttps://string-db.org/network/272631.gene:17575195Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis RV1693 TR:O33195 (EMBL:Z98268) (58 aa); Fasta score E(): 9.7e-13, 73.8% identity in 61 aa overlap.
tlyA protein networkhttps://string-db.org/network/272631.gene:17575196Cytotoxin/hemolysin; Highly similar to several proposed hemolysins including: Mycobacterium ulcerans TlyA TR:CAB83047 (EMBL:AJ271681) (281 aa); Fasta score E(): 0, 81.0% identity in 268 aa overla [...]
ML1359 protein networkhttps://string-db.org/network/272631.gene:17575197Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylatio [...]
recN protein networkhttps://string-db.org/network/272631.gene:17575198Recombination and DNA repair; May be involved in recombinational repair of damaged DNA.
ML1361 protein networkhttps://string-db.org/network/272631.gene:17575199Conserved membrane protein; Highly similar to Mycobacterium tuberculosis hypothetical protein Rv1697 TR:O33198 (EMBL:Z98268) (393 aa); Fasta score E(): 0, 90.6% identity in 393 aa overlap. Contai [...]
ML1362 protein networkhttps://string-db.org/network/272631.gene:17575200Possible conserved secreted protein; Pore-forming protein, which is involved in efflux of copper across the outer membrane. Essential for copper resistance and maintenance of a low intracellular [...]
pyrG protein networkhttps://string-db.org/network/272631.gene:17575201CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the fo [...]
ML1365 protein networkhttps://string-db.org/network/272631.gene:17575203Integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dime [...]
ML1367 protein networkhttps://string-db.org/network/272631.gene:17575205Possible regulatory protein; Similar to several proteins involved in plasmid/chromosome partioning or regulation of sporulation e.g. Neisseria meningitidis ParA family protein TR:CAB83392 (EMBL:A [...]
ML1368 protein networkhttps://string-db.org/network/272631.gene:17575206Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from m [...]
ML1369 protein networkhttps://string-db.org/network/272631.gene:17575207Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from m [...]
ML1370 protein networkhttps://string-db.org/network/272631.gene:17575208Possible pseudouridine synthase; Highly similar to several pseudouridylate synthases involved in the modification of ribosomal RNA e.g. Bacillus subtilis ribosomal large subunit pseudouridine syn [...]
cmk protein networkhttps://string-db.org/network/272631.gene:17575209Cytidylate kinase; Highly similar to several cytidylate kinases (EC 2.7.4.14) including: Bacillus subtilis SW:KCY_BACSU (P38493) (224 aa); Fasta score E(): 1.9e-28, 42.7% identity in 218 aa overl [...]
ML1372 protein networkhttps://string-db.org/network/272631.gene:17575210Possible GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (De [...]
ML1380 protein networkhttps://string-db.org/network/272631.gene:17575219Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV1780 TR:O53931 (EMBL:AL022021) (187 aa); Fasta score E(): 0, 82.4% identity in 187 aa overlap.
polA protein networkhttps://string-db.org/network/272631.gene:17575220DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
rpsA protein networkhttps://string-db.org/network/272631.gene:1757522130S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
ML1383 protein networkhttps://string-db.org/network/272631.gene:17575222Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; In the C-terminal section; belongs to the UPF0157 (GrpB) family.
uvrB protein networkhttps://string-db.org/network/272631.gene:17575226Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abn [...]
ML1389 protein networkhttps://string-db.org/network/272631.gene:17575228Conserved membrane protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV1635C TR:O06152 (EMBL:Z95554) (556 aa); Fasta score E(): 0, 71.6% identity in 528 aa overlap. Conta [...]
ML1390 protein networkhttps://string-db.org/network/272631.gene:17575229Conserved hypothetical protein; Highly similar to several proteins of undefined function e.g. Mycobacterium tuberculosis RV1636 TR:O06153 (EMBL:Z95554) (146 aa); Fasta score E(): 0, 89.0% identit [...]
ML1391 protein networkhttps://string-db.org/network/272631.gene:17575230Conserved hypothetical protein; Similar to several including: Streptomyces coelicolor putative hydrolase TR:Q9Z505 (EMBL:AL035591) (218 aa); Fasta score E(): 0, 50.9% identity in 224 aa overlap a [...]
uvrA protein networkhttps://string-db.org/network/272631.gene:17575231Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of [...]
lysX protein networkhttps://string-db.org/network/272631.gene:17575232C-term lysyl-tRNA synthase; Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produ [...]
InfC protein networkhttps://string-db.org/network/272631.gene:17575233Initiation factor 3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the avail [...]
rpmI protein networkhttps://string-db.org/network/272631.gene:17575234Highly similar to many 50s ribosomal L35 proteins, including: Escherichia coli SW:RL35_ECOLI (P07085) (64 aa); Fasta score E(): 2.3e-05, 43.4% identity in 53 aa overlap and Mycobacterium tubercul [...]
rplT protein networkhttps://string-db.org/network/272631.gene:1757523550S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing func [...]
tsnR protein networkhttps://string-db.org/network/272631.gene:17575236Putative rRNA methyltransferase; Similar to several proposed rRNA methylases (SpoU family) e.g. Mycobacterium tuberculosis Rv1644 TR:P94978 (EMBL:Z85982) (260 aa); Fasta score E(): 0, 72.8% ident [...]
ML1399 protein networkhttps://string-db.org/network/272631.gene:17575238Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV1647 TR:P94982 (EMBL:Z85982) (316 aa); Fasta score E(): 0, 74.0% identity in 312 aa overlap.
pheS protein networkhttps://string-db.org/network/272631.gene:17575240phenylalanyl-tRNA synthase [alpha] subunit; Highly similar to many phenylalanyl-tRNA synthetase alpha chains including: Escherichia coli SW:SYFA_ECOLI (P08312) (327 aa); Fasta score E(): 0, 45.9% [...]
pheT protein networkhttps://string-db.org/network/272631.gene:17575241phenylalanyl-tRNA synthase [beta] subunit; Highly similar to many phenylalanyl-tRNA synthetase beta chains including: Escherichia coli SW:SYFB_ECOLI (P07395) (795 aa); Fasta score E(): 0, 31.0% i [...]
argC protein networkhttps://string-db.org/network/272631.gene:17575245N-acetyl-[gamma]-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydro [...]
argJ protein networkhttps://string-db.org/network/272631.gene:17575246Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the [...]
argB protein networkhttps://string-db.org/network/272631.gene:17575247Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
argD protein networkhttps://string-db.org/network/272631.gene:17575248Highly similar to many acetylornithine aminotransferases (EC 2.6.1.11) involved in arginine biosynthesis, including: Escherichia coli SW:ARGD_ECOLI (P18335) (405 aa); Fasta score E(): 0, 38.7% id [...]
argF protein networkhttps://string-db.org/network/272631.gene:17575249Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs t [...]
argR protein networkhttps://string-db.org/network/272631.gene:17575250Arginine repressor; Regulates arginine biosynthesis genes.
argG protein networkhttps://string-db.org/network/272631.gene:17575251Arginosuccinate synthase; Highly similar to many argininosuccinate synthases (EC 6.3.4.5) involved in arginine biosynthesis, including: Streptomyces clavuligerus SW:ASSY_STRCL (P50986) (397 aa); [...]
argH protein networkhttps://string-db.org/network/272631.gene:17575252Arginosuccinate lyase; Highly similar to many argininosuccinate lyases (EC 4.3.2.1) involved in arginine biosynthesis, including: Escherichia coli SW:ARLY_ECOLI (P11447) (172 aa); BlastP Expect 9 [...]
ML1417 protein networkhttps://string-db.org/network/272631.gene:17575256Similar to several CDP-diacylglycerol pyrophosphatases (EC 3.6.1.26) involved in phospholipid biosynthesis, including: Salmonella typhimurium SW:CDH_SALTY (P26219) (251 aa); Fasta score E(): 1.6e [...]
ML1418 protein networkhttps://string-db.org/network/272631.gene:17575257Conserved hypothetical protein; Highly similar to several proteins of undefined function including: Mycobacterium tuberculosis TR:P71990 (EMBL:Z81360) (182 aa); Fasta score E(): 0, 86.3% identity [...]
ML1419 protein networkhttps://string-db.org/network/272631.gene:17575258Possible regulatory protein; The N-terminus is similar to several two component sensor histidine kinases e.g. Bacillus subtilis SW:KINA_BACSU (P16497) (634 aa); BlastP Expect 9.0. The C-terminus [...]
ML1420 protein networkhttps://string-db.org/network/272631.gene:17575259Hypothetical protein; Unknown function.
ML1423 protein networkhttps://string-db.org/network/272631.gene:17575262Conserved hypothetical protein; Highly similar to several proteins of undefined function including: Bacillus subtilis SW:YQHO_BACSU (P54513) (291 aa); Fasta score E(): 2.8e-24, 37.3% identity in [...]
ML1424 protein networkhttps://string-db.org/network/272631.gene:17575263Highly similar to several binding-protein-dependent transport proteins including: Escherichia coli SN-glycerol-3-phosphate transport ATP-binding protein SW:UGPC_ECOLI (P10907) (356 aa); Fasta sco [...]
ML1425 protein networkhttps://string-db.org/network/272631.gene:17575264Probable ABC-transport protein, inner membrane component; Highly similar to many putative ABC_transport proteins e.g. Mycobacterium tuberculosis sugar transport protein RV2039C TR:O53483 (EMBL:AL [...]
ML1426 protein networkhttps://string-db.org/network/272631.gene:17575265Probable ABC-transport protein, inner membrane component; Highly similar to many putative ABC_transport proteins e.g. Mycobacterium tuberculosis sugar transport protein RV2040C TR:O53484 (EMBL:AL [...]
ML1427 protein networkhttps://string-db.org/network/272631.gene:17575266Possible ABC-transport lipoprotein; Similar to several putative ABC_transport proteins e.g. Mycobacterium tuberculosis lipoprotein component of sugar transport system RV2041C TR:O53485 (EMBL:AL02 [...]
ML1430 protein networkhttps://string-db.org/network/272631.gene:17575268Possible membrane protein; Similar to Streptomyces coelicolor TR:CAB88440 (EMBL:AL353815) (136 aa); Fasta score E(): 9.5e-15, 52.4% identity in 105 aa overlap putative integral membrane protein. [...]
ML1439 protein networkhttps://string-db.org/network/272631.gene:17575277Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein [...]
ML1440 protein networkhttps://string-db.org/network/272631.gene:17575278Possible glycosyl transferase; Highly similar to several Eukaryotic dolichol-phosphate mannose synthases e.g. Saccharomyces cerevisiae SW:DPM1_YEAST (P14020) (267 aa); Fasta score E(): 4.6e-13, 3 [...]
ML1441 protein networkhttps://string-db.org/network/272631.gene:17575279Possible apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the [...]
ML1444 protein networkhttps://string-db.org/network/272631.gene:17575282Possible dienelactone hydrolase; Weakly similar to several carboxymethylenebutenolidases (EC 3.1.1.45) involved in 3-chlorocatechol degradation e.g. Pseudomonas putida SW:CLCD_PSEPU (P11453) (236 [...]
ML1445 protein networkhttps://string-db.org/network/272631.gene:17575283Hypothetical protein; Unknown function.
ML1446 protein networkhttps://string-db.org/network/272631.gene:17575284Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2061C TR:O86340 (EMBL:Z97984) (134 aa); Fasta score E(): 0, 70.2% identity in 131 aa overlap.
ML1448 protein networkhttps://string-db.org/network/272631.gene:17575286Similar to many ECF-subfamily RNA polymerase sigma factors including: Bacillus subtilis SigX SW:SIGX_BACSU (P35165) (194 aa); Fasta score E(): 1.3e-07, 32.0% identity in 128 aa overlap and Mycoba [...]
ML1452 protein networkhttps://string-db.org/network/272631.gene:17575290Possible phosphoglycerate mutase; Similar to several including: Salmonella typhimurium SW:COBC_SALTY (P39701) (234 aa); Fasta score E(): 5.4e-09, 29.4% identity in 197 aa overlap alpha-ribazole-5 [...]
ML1453 protein networkhttps://string-db.org/network/272631.gene:17575291Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 3 [...]
ML1454 protein networkhttps://string-db.org/network/272631.gene:17575292Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
proA protein networkhttps://string-db.org/network/272631.gene:17575296[gamma]-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cycliz [...]
ML1463 protein networkhttps://string-db.org/network/272631.gene:17575301Possible NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
proB protein networkhttps://string-db.org/network/272631.gene:17575302Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
ML1465 protein networkhttps://string-db.org/network/272631.gene:17575303GTP1/Obg-family GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rat [...]
rpmA protein networkhttps://string-db.org/network/272631.gene:17575304Highly similar to many 50s ribosomal proteins (L27) including: Escherichia coli SW:RL27_ECOLI (P02427) (84 aa); Fasta score E(): 5.8e-16, 63.9% identity in 83 aa overlap and Mycobacterium tubercu [...]
rplU protein networkhttps://string-db.org/network/272631.gene:1757530550S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
ML1468 protein networkhttps://string-db.org/network/272631.gene:17575306Possible ribonuclease; Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E (EC 3.1.4.-) SW:RNE_ECOLI (P21513) (1061 aa); Fasta score E(): 1.6e-22, 36.4% identity in [...]
ndk protein networkhttps://string-db.org/network/272631.gene:17575307Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, [...]
ML1470 protein networkhttps://string-db.org/network/272631.gene:17575308Conserved membrane protein; Highly similar to Mycobacterium tuberculosis hypothetical protein TR:O53173 (EMBL:AL021246) (123 aa); Fasta score E(): 1.5e-22, 66.7% identity in 108 aa overlap.
folC protein networkhttps://string-db.org/network/272631.gene:17575309Highly similar to many folylpolyglutamate synthases (EC 6.3.2.17) including: Lactobacillus casei SW:FOLC_LACCA (P15925) (428 aa); Fasta score E(): 0, 34.1% identity in 437 aa overlap and Mycobact [...]
valS protein networkhttps://string-db.org/network/272631.gene:17575310valyl-tRNA synthase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, [...]
clpX protein networkhttps://string-db.org/network/272631.gene:17575315ATP-dependent Clp protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the abs [...]
ML1478 protein networkhttps://string-db.org/network/272631.gene:17575316Highly similar to many transferases e.g. Escherichia coli homocysteine S-methyltransferase (EC 2.1.1.10) involved in methionine biosynthesis SW:MMUM_ECOLI (Q47690) (310 aa); Fasta score E(): 0, 4 [...]
clpP2 protein networkhttps://string-db.org/network/272631.gene:17575317ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degrada [...]
clpP protein networkhttps://string-db.org/network/272631.gene:17575318ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degrada [...]
ML1481 protein networkhttps://string-db.org/network/272631.gene:17575319Possible molecular chaperone; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomer [...]
ML1484 protein networkhttps://string-db.org/network/272631.gene:17575324Possible phosphopentose isomerase; Catalyzes the interconversion of ribulose-5-P and ribose-5-P.
ML1485 protein networkhttps://string-db.org/network/272631.gene:17575325Conserved hypothetical protein; Highly similar to several proteins of undefined function e.g. Mycobacterium tuberculosis RV2466C TR:O53193 (EMBL:AL02124) (207 aa); Fasta score E(): 0, 80.6% ident [...]
ML1486 protein networkhttps://string-db.org/network/272631.gene:17575326Highly similar to many aminopeptidases including: Streptomyces lividans aminopeptidase N (EC 3.4.11.2) SW:AMPN_STRLI (Q11010) (857 aa); Fasta score E(): 0, 51.6% identity in 866 aa overlap and My [...]
ML1488 protein networkhttps://string-db.org/network/272631.gene:17575328Possible aminotransferase; Weakly similar to several putative aminotransferases including: Neisseria meningitidis TR:AAF41303 (EMBL:AE002441) (395 aa); Fasta score E(): 5.1e-13, 29.8% identity in [...]
fdxA protein networkhttps://string-db.org/network/272631.gene:17575329Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
ML1492 protein networkhttps://string-db.org/network/272631.gene:17575332Conserved hypothetical protein; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine; In the C-termina [...]
ML1494 protein networkhttps://string-db.org/network/272631.gene:17575334Conserved membrane protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV1171 TR:O50427 (EMBL:AL010186) (120 aa); Fasta score E(): 7.4e-24, 62.2% identity in 111 aa overlap [...]
ML1495 protein networkhttps://string-db.org/network/272631.gene:17575335Conserved hypothetical protein; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
ML1497 protein networkhttps://string-db.org/network/272631.gene:17575337Possible secreted protein; Similar to several proteins of undefined function e.g. Mycobacterium tuberculosis RV1166 TR:O50422 (EMBL:AL01018) (635 aa); Fasta score E(): 0, 80.4% identity in 632 aa [...]
ML1498 protein networkhttps://string-db.org/network/272631.gene:17575338Possible GTP-binding, protein elongation factor; Highly similar to several GTP-binding proteins including: Escherichia coli SW:TYPA_ECOLI (P32132) (591 aa); Fasta score E(): 0, 46.1% identity in [...]
ML1503A protein networkhttps://string-db.org/network/272631.gene:17575344Conserved hypothetical protein; Unknown but orthologous to M. tuberculosis Rv1159A and similar to hypothetical proteins in Streptomyces coelicolor (SC5C7.25) and archaebacteria. FASTA scores: Rv1 [...]
ML1504 protein networkhttps://string-db.org/network/272631.gene:17575345Probable conserved membrane protein; Highly similar to several proteins of undefined function e.g. Mycobacterium tuberculosis possible membrane protein RV1159 TR:O06557 (EMBL:Z95584) (431 aa); Fa [...]
ML1505 protein networkhttps://string-db.org/network/272631.gene:17575346Conserved hypothetical Proline rich protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV1158C TR:O06556 (EMBL:Z95584) (227 aa); Fasta score E(): 1.1e-16, 51.7% identity i [...]
ML1506 protein networkhttps://string-db.org/network/272631.gene:17575347Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV1157C TR:O06555 (EMBL:Z95584) (371 aa); Fasta score E(): 0, 68.0% identity in 369 aa overlap. N [...]
ML1508 protein networkhttps://string-db.org/network/272631.gene:17575349Conserved hypothetical protein; Highly similar to several proteins of undefined function including M. tuberculosis RV1155 TR:O06553 (EMBL:Z95584) (147 aa); Fasta score E(): 0, 87.8% identity in 1 [...]
ML1511 protein networkhttps://string-db.org/network/272631.gene:17575352Conserved hypothetical protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several pro [...]
ML1512 protein networkhttps://string-db.org/network/272631.gene:17575353Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
dapA protein networkhttps://string-db.org/network/272631.gene:17575354Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
ML1514 protein networkhttps://string-db.org/network/272631.gene:17575355Putative mycobacteriophage protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetr [...]
ML1517 protein networkhttps://string-db.org/network/272631.gene:17575358Hypothetical protein; Function unknown.
folA protein networkhttps://string-db.org/network/272631.gene:17575359Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
thyA protein networkhttps://string-db.org/network/272631.gene:17575360Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate ( [...]
ML1525 protein networkhttps://string-db.org/network/272631.gene:17575366Similar to hypothetical proteins from Streptomyces coelicolor TR:Q9RD46 (EMBL:AL133424) (151 aa); Fasta score E(): 1.3e-28, 56.1% identity in 148 aa overlap and Mycobacterium tuberculosis RV2771C [...]
ML1526 protein networkhttps://string-db.org/network/272631.gene:17575367Conserved membrane protein; Highly similar to many proteins of undefined function e.g. Mycobacterium tuberculosis RV2772C TR:O33314 (EMBL:AL008967) (157 aa); Fasta score E(): 0, 76.6% identity in [...]
ald protein networkhttps://string-db.org/network/272631.gene:17575373Highly similar to many alanine dehydrogenases (EC 1.4.1.1) including: Bacillus sphaericus SW:DHA_BACSH (P175566) (372 aa); Fasta score E(): 0, 53.4% identity in 365 aa overlap and Mycobacterium t [...]
ML1536 protein networkhttps://string-db.org/network/272631.gene:17575377Conserved hypothetical protein; Highly similar to several Mycobacterium tuberculosis proteins of undefined function e.g. SW:YH98_MYCTU (O53947) (610 aa); Fasta score E(): 0, 89.7% identity in 609 [...]
ML1537 protein networkhttps://string-db.org/network/272631.gene:17575378Possible secreted protein; Highly similar to a protein of unknown function from Mycobacterium tuberculosis RV1797 TR:O53946 (EMBL:AL022021) (406 aa); Fasta score E(): 0, 68.5% identity in 406 aa [...]
ML1538 protein networkhttps://string-db.org/network/272631.gene:17575379Possible protease; Highly similar to several from Mycobacterium tuberculosis including: a putative protease RV0291 TR:O53695 (EMBL:AL021930) (461 aa); Fasta score E(): 0, 37.6% identity in 572 aa [...]
ML1539 protein networkhttps://string-db.org/network/272631.gene:17575380Probable membrane protein; Similar to several Mycobacterium tuberculosis proteins of undefined function e.g. putative membrane protein RV1795 TR:O53944 (EMBL:AL022021) (503 aa); Fasta score E(): [...]
ML1540 protein networkhttps://string-db.org/network/272631.gene:17575381Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV1794 TR:O53943 (EMBL:AL022021) (300 aa); Fasta score E(): 0, 88.0% identity in 300 aa overlap.
ML1543 protein networkhttps://string-db.org/network/272631.gene:17575384Possible SpoIIIE-family membrane protein; Highly similar, in parts, to several from Mycobacterium tuberculosis e.g. the C-terminus is similar to hypothetical protein TR:O53935 (EMBL:AL022021) (93 [...]
ML1544 protein networkhttps://string-db.org/network/272631.gene:17575385Conserved membrane protein; Highly similar to many Mycobacterium tuberculosis proteins of unknown function including:RV1782 TR:O53933 (EMBL:AL022021) (506 aa); Fasta score E(): 0, 82.6% identity [...]
truB protein networkhttps://string-db.org/network/272631.gene:17575387tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
ML1547 protein networkhttps://string-db.org/network/272631.gene:17575388Conserved hypothetical protein; Similar to a number of proteins essential for the production of iron chelators e.g. Escherichia coli enterobactin synthetase component D SW:ENTD_ECOLI (P19925) (20 [...]
ML1548 protein networkhttps://string-db.org/network/272631.gene:17575389Conserved hypothetical protein; Highly similar to several proteins of unknown function including: Streptomyces coelicolor TR:O88028 (EMBL:AL031107) (295 aa); Fasta score E(): 0, 54.4% identity in [...]
proS protein networkhttps://string-db.org/network/272631.gene:17575394Prolyl tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
ML1555 protein networkhttps://string-db.org/network/272631.gene:17575396Probable ribosome-binding factor; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits [...]
infB protein networkhttps://string-db.org/network/272631.gene:17575397Initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribo [...]
ML1557 protein networkhttps://string-db.org/network/272631.gene:17575398Conserved hypothetical protein; Highly similar to several proteins of undefined function including: Mycobacterium tuberculosis RV2840C TR:P71612 (EMBL:Z81331) (99 aa); Fasta score E(): 1.7e-30, 8 [...]
nusA protein networkhttps://string-db.org/network/272631.gene:17575399Probable transcription termination/antitermination factor; Participates in both transcription termination and antitermination.
ML1560 protein networkhttps://string-db.org/network/272631.gene:17575401Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2843 TR:O05816 (EMBL:Z95207) (181 aa); Fasta score E(): 2e-31, 70.2% identity in 168 aa overlap [...]
ML1561 protein networkhttps://string-db.org/network/272631.gene:17575402Conserved hypothetical protein; Highly similar to proteins of unknown function from Streptomyces coelicolor TR:CAB91137 (EMBL:AL355913) (167 aa); Fasta score E(): 1.4e-07, 35.8% identity in 137 a [...]
ML1562 protein networkhttps://string-db.org/network/272631.gene:17575403Highly similar to several transmembrane transport proteins including: Streptomyces lipmanii SW:PUR8_STRLP (P42670) (503 aa); Fasta score E(): 0, 33.3% identity in 481 aa overlap and Mycobacterium [...]
ML1572 protein networkhttps://string-db.org/network/272631.gene:17575413Hypothetical protein; Function unknown.
ML1573 protein networkhttps://string-db.org/network/272631.gene:17575414Possible amidotransferase; Similar to several proteins of undefined function e.g. Mycobacterium tuberculosis RV2859C TR:O33341. Also similar in regions to Dictyostelium discoideum GMP synthase (E [...]
mapB protein networkhttps://string-db.org/network/272631.gene:17575417Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharg [...]
ML1577 protein networkhttps://string-db.org/network/272631.gene:17575418Similar to many penecillin binding proteins e.g. Streptomyces clavuligerus high molecular weight group B penicillin binding protein TR:P72405 (EMBL:U56256) (551 aa); Fasta score E(): 6.3e-27, 29. [...]
gcpE protein networkhttps://string-db.org/network/272631.gene:17575422Conserved hypothetical protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
ML1582 protein networkhttps://string-db.org/network/272631.gene:17575423Probable integral membrane protein; A probable intramembrane site-2 protease (S2P) that cleaves type-2 transmembrane proteins within their membrane-spanning domains. Regulated intramembrane prote [...]
ML1583 protein networkhttps://string-db.org/network/272631.gene:17575424Possible 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate [...]
ML1584 protein networkhttps://string-db.org/network/272631.gene:17575425Possible conserved membrane protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2876 SW:YS76_MYCTU (Q10802) (104 aa); Fasta score E(): 3.3e-26, 75.0% identity in 88 aa ov [...]
ML1589 protein networkhttps://string-db.org/network/272631.gene:17575430Possible phosphatidate cytidylyltransferase; The C-terminus of this protein is highly similar to many proteins involved with phospholipid biosynthesis e.g. Escherichia coli phosphatidate cytidyly [...]
frr protein networkhttps://string-db.org/network/272631.gene:17575431Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
ML1591 protein networkhttps://string-db.org/network/272631.gene:17575432Possible uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
ML1596 protein networkhttps://string-db.org/network/272631.gene:17575437Possible amidase; Highly similar to several proposed amidases including: Pseudomonas putida SW:AMID_PSEPU (O69768) (466 aa); Fasta score E(): 2.9e-19, 29.0% identity in 469 aa overlap and Mycobac [...]
tsf protein networkhttps://string-db.org/network/272631.gene:17575438Elongation factor EF-Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on [...]
rpsB protein networkhttps://string-db.org/network/272631.gene:17575439Highly similar to many 30s ribosomal proteins (S2) including: Bacillus subtilis SW:RS2_BACSU (P21464) (245 aa); Fasta score E(): 0, 57.6% identity in 250 aa overlap and Mycobacterium tuberculosis [...]
xerC protein networkhttps://string-db.org/network/272631.gene:17575441Integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dime [...]
ML1602 protein networkhttps://string-db.org/network/272631.gene:17575443Hypothetical protein; Function unknown.
ML1603 protein networkhttps://string-db.org/network/272631.gene:17575444Hypothetical protein; Function unknown.
ML1604 protein networkhttps://string-db.org/network/272631.gene:17575445Hypothetical protein; Function unknown.
ML1607 protein networkhttps://string-db.org/network/272631.gene:17575448Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2898C SW:YS98_MYCTU (Q10819). (128 aa); Fasta score E(): 7.9e-19, 58.3% identity in 96 aa overl [...]
ML1610 protein networkhttps://string-db.org/network/272631.gene:17575451Conserved hypothetical protein; Similar to several proteins of unknown function from Mycobacterium tuberculosis e.g. SW:YT01_MYCTU (Q10822) (101 aa); Fasta score E(): 0, 99.0% identity in 101 aa [...]
rnhB protein networkhttps://string-db.org/network/272631.gene:17575452Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
ML1612 protein networkhttps://string-db.org/network/272631.gene:17575453Similar in parts to many proposed signal peptidases e.g. Bacillus subtilis SW:LEPT_BACSU (P71013) (193 aa); Fasta score E(): 1.1e-07, 31.0% identity in 226 aa overlap and Mycobacterium tuberculos [...]
rplS protein networkhttps://string-db.org/network/272631.gene:1757545450S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
trmD protein networkhttps://string-db.org/network/272631.gene:17575456tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rimM protein networkhttps://string-db.org/network/272631.gene:1757545716S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Ess [...]
ML1617 protein networkhttps://string-db.org/network/272631.gene:17575458Conserved hypothetical protein; Highly similar to many proteins of undefined function e.g. Mycobacterium tuberculosis Rv2908c SW:YT08_MYCTU (Q10826) (80 aa); Fasta score E(): 6.5e-28, 93.8% ident [...]
rpsP protein networkhttps://string-db.org/network/272631.gene:17575459Highly similar to many 30s ribosomal proteins (S16) including: Bacillus subtilis SW:RS16_BACSU (P21474) (89 aa); Fasta score E(): 2.1e-10, 45.1% identity in 82 aa overlap and Mycobacterium tuberc [...]
ffh protein networkhttps://string-db.org/network/272631.gene:17575463Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nasce [...]
htpG protein networkhttps://string-db.org/network/272631.gene:17575464Heat shock protein Hsp90 family; Molecular chaperone. Has ATPase activity.
ML1624 protein networkhttps://string-db.org/network/272631.gene:17575465Conserved hypothetical protein; Highly similar to several proteins of unknown function including: Mycobacterium tuberculosis RV2917 SW:YT17_MYCTU (Q10966) (626 aa); Fasta score E(): 0, 79.8% iden [...]
ML1628 protein networkhttps://string-db.org/network/272631.gene:17575469Possible SRP family of GTP-binding protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal [...]
smc protein networkhttps://string-db.org/network/272631.gene:17575470Possible cell division protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
glnE protein networkhttps://string-db.org/network/272631.gene:17575471Glutamate-ammonia-ligase adenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the [...]
glnA2 protein networkhttps://string-db.org/network/272631.gene:17575472Glutamine synthase class II; Highly similar to many glutamine synthetases (EC 6.3.1.2) including: Bacillus subtilis SW:GLNA_BACSU (P12425) (443 aa); Fasta score E(): 0, 45.4% identity in 445 aa o [...]
ML1632 protein networkhttps://string-db.org/network/272631.gene:17575473Possible hydrolase; Highly similar to several including: Streptomyces lividans tripeptidylaminopeptidase precursor TR:Q54410 (EMBL:L27466) (537 aa); Fasta score E(): 0, 30.9% identity in 489 aa o [...]
ML1633 protein networkhttps://string-db.org/network/272631.gene:17575474Possible secreted hydrolase; Highly similar to several including: Streptomyces lividans tripeptidylaminopeptidase precursor TR:Q54410 (EMBL:L27466) (537 aa); Fasta score E(): 4.3e-23, 30.7% ident [...]
panB protein networkhttps://string-db.org/network/272631.gene:175754763-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to [...]
ML1637 protein networkhttps://string-db.org/network/272631.gene:17575479Conserved hypothetical protein; Similar in parts to many. The N-terminus is similar to several ribonucleases e.g. Escherichia coli ribonuclease HI (EC 3.1.26.4) SW:RNH_ECOLI (P00647) (430 aa); Bl [...]
ML1638 protein networkhttps://string-db.org/network/272631.gene:17575480Conserved hypothetical protein; Highly similar to several proteins of undefined function e.g. Mycobacterium tuberculosis RV2229C SW:YM29_MYCTU (Q10513) (245 aa); Fasta score E(): 0, 60.9% identit [...]
ML1639 protein networkhttps://string-db.org/network/272631.gene:17575481Conserved hypothetical protein; Highly similar to several proteins of undefined function e.g. Mycobacterium tuberculosis RV2230C SW:YM30_MYCTU (Q10514) (379 aa); Fasta score E(): 0, 79.5% identit [...]
ML1644 protein networkhttps://string-db.org/network/272631.gene:17575486Conserved membrane protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2235 SW:YM35_MYCTU (Q10517) (271 aa); Fasta score E(): 0, 74.2% identity in 271 aa overlap. Contain [...]
ML1649 protein networkhttps://string-db.org/network/272631.gene:17575492Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV2239C SW:YM39_MYCTU (Q10521) (158 aa); Fasta score E(): 0, 86.4% identity in 140 aa overlap.
aceE protein networkhttps://string-db.org/network/272631.gene:17575494Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
ML1652 protein networkhttps://string-db.org/network/272631.gene:17575495Conserved hypothetical protein; Highly similar to proteins of unknown function from Streptomyces coelicolor TR:Q9RDP8 (EMBL:AL133423) (401 aa); Fasta score E(): 4.3e-26, 42.0% identity in 383 aa [...]
fabD protein networkhttps://string-db.org/network/272631.gene:17575496Malonyl CoA-[ACP] transacylase; Similar to many malonyl CoA-acyl carrier protein transacylases (EC 2.3.1.39) involved in fatty acid biosynthesis, including: Salmonella typhimurium SW:FABD_SALTY ( [...]
acpM protein networkhttps://string-db.org/network/272631.gene:17575497Acyl carrier protein (meromycolate extension); Acyl carrier protein involved in meromycolate extension.
kasA protein networkhttps://string-db.org/network/272631.gene:175754983-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Belongs to the thiolase [...]
kasB protein networkhttps://string-db.org/network/272631.gene:175754993-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Belongs to the thiolase [...]
ML1657 protein networkhttps://string-db.org/network/272631.gene:17575500Acetyl/propionyl CoA carboxylase [beta] subunit; Highly similar to many propionyl-CoA carboxylases involved in fatty acid catabolism including: Rhodococcus erythropolis SW:PCCB_RHOER (Q06101) (47 [...]
fpg protein networkhttps://string-db.org/network/272631.gene:17575501formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a [...]
rnc protein networkhttps://string-db.org/network/272631.gene:17575502RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, a [...]
ML1660 protein networkhttps://string-db.org/network/272631.gene:17575503Conserved hypothetical protein; Similar to several proteins of undefined function e.g. Mycobacterium tuberculosis RV2926C TR:YT26_MYCTU; To M.tuberculosis Rv2926c.
ML1661 protein networkhttps://string-db.org/network/272631.gene:17575504Conserved hypothetical protein; Similar to several proteins of undefined function e.g. Mycobacterium tuberculosis RV2927C TR:YT27_MYCTU; To M.tuberculosis Rv2927c.
coaD protein networkhttps://string-db.org/network/272631.gene:17575506Probable phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacter [...]
ML1664 protein networkhttps://string-db.org/network/272631.gene:17575507Conserved hypothetical protein; Similar to several proteins of undefined function including: Neisseria meningitidis possible DNA methylase TR:CAB83466 (EMBL:AL162752) (189 aa); Fasta score E(): 3 [...]
ML1666 protein networkhttps://string-db.org/network/272631.gene:17575509Conserved integral membrane protein; Similar to several proteins of undefined function including: Streptomyces coelicolorputative integral membrane protein TR:CAB93387 (EMBL:AL357523) (240 aa); F [...]
ML1667 protein networkhttps://string-db.org/network/272631.gene:17575510Possible conserved membrane protein; Similar to several proteins of undefined function e.g. Mycobacterium tuberculosis RV2969C TR:O33272 (EMBL:Z83018) (255 aa); Fasta score E(): 0, 65.5% identity [...]
ML1669 protein networkhttps://string-db.org/network/272631.gene:17575512Possible oxidoreductase of Aldo/keto reductase family; Highly similar to many putative oxidoreductases including: Escherichia coli SW:YQHE_ECOLI (Q46857) (275 aa); Fasta score E(): 0, 46.1% ident [...]
recG protein networkhttps://string-db.org/network/272631.gene:17575514ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding act [...]
ung protein networkhttps://string-db.org/network/272631.gene:17575518uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
thiL protein networkhttps://string-db.org/network/272631.gene:17575519Probable thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs t [...]
ML1677 protein networkhttps://string-db.org/network/272631.gene:17575520Possible secreted protein; Highly similar to Mycobacterium tuberculosis hypothetical protein Rv2980 TR:P95115 (EMBL:Z83018) (181 aa); Fasta score E(): 0, 67.2% identity in 177 aa overlap. Contain [...]
ddlA protein networkhttps://string-db.org/network/272631.gene:17575521D-alanine-D-alanine ligase A; Cell wall formation.
gpdA protein networkhttps://string-db.org/network/272631.gene:17575522Highly similar to many glycerol-3-phosphate dehydrogenases (EC 1.1.1.8) including: Escherichia coli SW:GPDA_ECOLI (P37606) (339 aa); Fasta score E(): 0, 39.9% identity in 341 aa overlap and Mycob [...]
ML1680 protein networkhttps://string-db.org/network/272631.gene:17575523Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It i [...]
ML1681 protein networkhttps://string-db.org/network/272631.gene:17575524Possible polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family.
ML1682 protein networkhttps://string-db.org/network/272631.gene:17575525Conserved hypothetical protein; Similar to several proteins of undefined function e.g. Mycobacterium tuberculosis TR:P95110 (EMBL:Z83018) (317 aa); Fasta score E(): 0, 71.5% identity in 316 aa ov [...]
ML1683 protein networkhttps://string-db.org/network/272631.gene:17575526Probable histone-like protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
leuD protein networkhttps://string-db.org/network/272631.gene:175755273-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. Leu [...]
leuC protein networkhttps://string-db.org/network/272631.gene:175755283-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
gltS protein networkhttps://string-db.org/network/272631.gene:17575533glutamyl-tRNA synthase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of [...]
ML1689 protein networkhttps://string-db.org/network/272631.gene:17575534Possible hydrolase; Similar in parts to several putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerases including: Methanobacterium thermoautotrophicum TR:O27551 (EMBL:AE000911) (260 aa); Fasta s [...]
leuB protein networkhttps://string-db.org/network/272631.gene:175755363-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-met [...]
serA protein networkhttps://string-db.org/network/272631.gene:17575537D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Als [...]
ilvC protein networkhttps://string-db.org/network/272631.gene:17575539Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yie [...]
ilvN protein networkhttps://string-db.org/network/272631.gene:17575540Highly similar to many acetolactate synthases, small subunit, (EC 4.1.3.18) involved in valine and isoleucine biosynthesis, including: Mycobacterium avium SW:ILVH_MYCAV (Q59499) (167 aa); Fasta s [...]
ilvB protein networkhttps://string-db.org/network/272631.gene:17575541Highly similar to many acetolactate synthases, large subunit, (EC 4.1.3.18) involved in valine and isoleucine biosynthesis, including: Mycobacterium avium SW:ILVB_MYCAV (Q59498) (621 aa); Fasta s [...]
ML1698 protein networkhttps://string-db.org/network/272631.gene:17575543Conserved membrane protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV3005C TR:O53252 (EMBL:AL021287) (279 aa); Fasta score E(): 0, 68.7% identity in 278 aa overlap. Con [...]
ML1699 protein networkhttps://string-db.org/network/272631.gene:17575544Putative lipoprotein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV3006 TR:O53253 (EMBL:AL021287) (373 aa); Fasta score E(): 0, 87.1% identity in 373 aa overlap. Contains p [...]
gatB protein networkhttps://string-db.org/network/272631.gene:17575545glutamyl-tRNA(Gln) amidotransferase, subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) i [...]
pfkA protein networkhttps://string-db.org/network/272631.gene:175755466-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase typ [...]
gatA protein networkhttps://string-db.org/network/272631.gene:17575547glutamyl-tRNA(Gln) amidotransferase, subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl- [...]
gatC protein networkhttps://string-db.org/network/272631.gene:17575548glutamyl-tRNA(Gln) amidotransferase, subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) i [...]
ML1704 protein networkhttps://string-db.org/network/272631.gene:17575549Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV3013 TR:O53260 (EMBL:AL021287) (218 aa); Fasta score E(): 0, 84.3% identity in 216 aa overlap.
ligA protein networkhttps://string-db.org/network/272631.gene:17575550DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy sourc [...]
ML1706 protein networkhttps://string-db.org/network/272631.gene:17575551Conserved hypothetical protein; Highly similar to proteins of undefined function from Streptomyces coelicolor TR:Q9Z586 (EMBL:AL035569) (331 aa); Fasta score E(): 0, 38.6% identity in 337 aa over [...]
ML1707 protein networkhttps://string-db.org/network/272631.gene:17575552Probable tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
ML1708 protein networkhttps://string-db.org/network/272631.gene:17575553Highly similar to many aminotransferases resembling NifS, a protein of unknown function located within many nitrogen fixation gene clusters e.g. Azotobacter vinelandii SW:NIFS_AZOVI (P05341) (402 [...]
eftA protein networkhttps://string-db.org/network/272631.gene:17575556Electron transfer flavoprotein [alpha] subunit; The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respirat [...]
eftB protein networkhttps://string-db.org/network/272631.gene:17575557Electron transfer flavoprotein [beta] subunit; The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respirato [...]
ML1713 protein networkhttps://string-db.org/network/272631.gene:17575558Conserved hypothetical protein; Highly similar to several proteins of unknown function including: Mycobacterium tuberculosis RV3030 TR:O53277 (EMBL:AL021287) (274 aa); Fasta score E(): 0, 78.2% i [...]
ML1714 protein networkhttps://string-db.org/network/272631.gene:17575559Conserved hypothetical protein; Highly similar to several proteins of unknown function including: Mycobacterium tuberculosis hypothetical protein RV3031 TR:O53278 (EMBL:AL021287) (526 aa); Fasta [...]
ML1715 protein networkhttps://string-db.org/network/272631.gene:17575560Putative transferase; Highly similar to several proteins of undefined function including: Mycobacterium tuberculosis hypothetical protein RV3032 TR:O53279 (EMBL:AL021287) (414 aa); Fasta score E( [...]
ML1719 protein networkhttps://string-db.org/network/272631.gene:17575564Conserved hypothetical protein; The C-terminus of this protein is weakly similar to several including: Escherichia coli putative lipopolysaccharide biosynthesis O-acetyl transferase SW:WBBJ_ECOLI [...]
ML1720 protein networkhttps://string-db.org/network/272631.gene:17575565Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV3035 TR:O53282 (EMBL:AL021287) (360 aa); Fasta score E(): 0, 75.8% identity in 363 aa overlap.
ML1723 protein networkhttps://string-db.org/network/272631.gene:17575568Similar to Mycobacterium tuberculosis hypothetical protein RV3038C TR:O53285 (EMBL:AL021287) (327 aa); Fasta score E(): 0, 80.7% identity in 327 aa overlap.
ML1724 protein networkhttps://string-db.org/network/272631.gene:17575569Putative enoyl-CoA hydratase/isomerase; Similar to several proposed enoyl-CoA hydratases (EC 4.2.1.17) including: Rhizobium meliloti SW:ECHH_RHIME (Q52995) (257 aa); Fasta score E(): 1.8e-19, 34. [...]
ML1726 protein networkhttps://string-db.org/network/272631.gene:17575571Highly similar to many putative ABC transport, ATP-binding proteins including:Streptomyces coelicolor TR:CAB76322 (EMBL:AL158060) (279 aa); Fasta score E(): 0, 44.4% identity in 277 aa overlap an [...]
ML1727 protein networkhttps://string-db.org/network/272631.gene:17575572Similar in the C-terminus to many phosphoserine phosphatases (EC 3.1.3.3) including: Escherichia coli SW:SERB_ECOLI (P06862) (322 aa); Fasta score E(): 1.7e-29, 38.5% identity in 309 aa overlap a [...]
ML1728 protein networkhttps://string-db.org/network/272631.gene:17575573Cytochrome C oxidase, polypeptide I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the e [...]
fecB protein networkhttps://string-db.org/network/272631.gene:17575574Putative FeIII-dicitrate transporter lipoprotein; Highly similar to several proteins involved in iron transport including: Mycobacterium avium FecB precursor TR:AAF73189 (EMBL:AF151098) (364 aa); [...]
adhA protein networkhttps://string-db.org/network/272631.gene:17575575Alcohol dehydrogenase; Highly similar to many Prokaryotic and Eukaryotic dehydrogenases including: Mycobacterium tuberculosis RV3045 SW:ADH_MYCTU (P31975) (346 aa); Fasta score E(): 0, 85.8% iden [...]
nrdF protein networkhttps://string-db.org/network/272631.gene:17575576Ribonucleotide reductase small subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similari [...]
ML1733 protein networkhttps://string-db.org/network/272631.gene:17575578Putative TetR-family transcriptional regulator; Similar to Mycobacterium tuberculosis RV3050C TR:O53295 (EMBL:AL021287) (246 aa); Fasta score E(): 0, 86.6% identity in 238 aa overlap. Contains a [...]
nrdE protein networkhttps://string-db.org/network/272631.gene:17575579Ribonucleoside diphosphate reductase [alpha] chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [...]
nrdI protein networkhttps://string-db.org/network/272631.gene:17575580NrdI-family protein; Probably involved in ribonucleotide reductase function.
nrdH protein networkhttps://string-db.org/network/272631.gene:17575581Highly similar to many glutaredoxin-like proteins involved in electron transport for the ribonucleotide reductase system NrdEF, including: Escherichia coli SW:NRDH_ECOLI (Q47414) (81 aa); Fasta s [...]
ML1740 protein networkhttps://string-db.org/network/272631.gene:17575585Possible short chain reductase; Similar to several including: Thermotoga maritima 3-oxoacyl-[acyl-carrier protein] reductase SW:FABG_THEMA (Q9X248) (246 aa); Fasta score E(): 1.4e-18, 33.2% ident [...]
ML1750 protein networkhttps://string-db.org/network/272631.gene:17575595Conserved hypothetical protein; The C-terminus of this protein is highly similar to many including several hypothetical proteins and putative phosphodiesterases e.g. Mycobacterium tuberculosis RV [...]
ML1751 protein networkhttps://string-db.org/network/272631.gene:17575596Conserved hypothetical protein; Similar to several proteins of undefined function e.g. Mycobacterium tuberculosis SW:YD55_MYCTU (Q11025) (715 aa); Fasta score E(): 0, 57.3% identity in 705 aa ove [...]
ML1752 protein networkhttps://string-db.org/network/272631.gene:17575597Conserved hypothetical protein; Similar to many including the C-terminus of several putative phosphodiesterases e.g. Streptomyces coelicolor TR:Q9Z584 (EMBL:AL035569) (746 aa); Fasta score E(): 2 [...]
ML1753 protein networkhttps://string-db.org/network/272631.gene:17575598Possible transcriptional regulator; Highly similar to many from Mycobacterium tuberculosis e.g. probable transcriptional regulatory protein RV1358 TR:Q11028 (EMBL:Z75555) (1159 aa); Fasta score E [...]
sdaA protein networkhttps://string-db.org/network/272631.gene:17575600Highly similar to many L-serine dehydratases (EC 4.2.1.13) including: Escherichia coli SW:TDCG_ECOLI (P42630) (454 aa); Fasta score E(): 0, 53.2% identity in 457 aa overlap and Mycobacterium tube [...]
ML1756 protein networkhttps://string-db.org/network/272631.gene:17575601Probable multidrug resistance protein; Multidrug efflux pump. Confers resistance to tetraphenylphosphonium (TPP), erythromycin, ethidium bromide, acriflavine, safranin O and pyronin Y (By similar [...]
ML1761 protein networkhttps://string-db.org/network/272631.gene:17575608Hypothetical protein; Unknown function.
ML1763 protein networkhttps://string-db.org/network/272631.gene:17575610Hypothetical protein; Unknown function.
uspA protein networkhttps://string-db.org/network/272631.gene:17575615Sugar transport integral membrane protein; Similar to M. tuberculosis Rv2316 TR:P71896 (EMBL:Z79702) (290 aa); Fasta score E(): 0, 82.4% identity in 289 aa overlap probable sugar transport protei [...]
uspE protein networkhttps://string-db.org/network/272631.gene:17575616Sugar transport integral membrane protein; Similar to M. tuberculosis Rv2317 TR:P71895 (EMBL:Z79702) (274 aa); Fasta score E(): 0, 85.0% identity in 274 aa overlap probable sugar transport protei [...]
uspC protein networkhttps://string-db.org/network/272631.gene:17575617Sugar transport periplasmic binding protein; Similar to M. tuberculosis RV2318 TR:P71894 (EMBL:Z79702) (440 aa); Fasta score E(): 0, 74.7% identity in 446 aa overlap probable sugar transport peri [...]
ML1781 protein networkhttps://string-db.org/network/272631.gene:17575628Conserved hypothetical protein; Similar to M. tuberculosis Rv2256c TR:O53530 (EMBL:AL021925) (177 aa); Fasta score E(): 0, 93.5% identity in 170 aa overlap, and to other hypothetical preoteins e. [...]
ML1782 protein networkhttps://string-db.org/network/272631.gene:17575629Conserved hypothetical protein; Similar to M. tuberculosis Rv2257c TR:O53531 (EMBL:AL021925) (272 aa); Fasta score E(): 0, 76.4% identity in 271 aa overlap, and to Streptomyces coelicolor SC4A7.0 [...]
ML1783 protein networkhttps://string-db.org/network/272631.gene:17575630Putative transcriptional regulator; Similar to M. tuberculosis Rv2258c TR:O53532 (EMBL:AL021925) (353 aa); Fasta score E(): 0, 65.2% identity in 273 aa overlap but shorter at N-terminus and frame [...]
adhE2 protein networkhttps://string-db.org/network/272631.gene:17575631Putative alcohol dehydrogenase (Zn dependent); Similar to M. tuberculosis adhE2 Rv2259 TR:O53533 (EMBL:AL021925) (361 aa); Fasta score E(): 0, 88.9% identity in 361 aa overlap, and to other alcoh [...]
ML1791 protein networkhttps://string-db.org/network/272631.gene:17575638Similar to M. tuberculosis hypothetical protein Rv1976c TR:O53977 (EMBL:AL022073) (135 aa); Fasta score E(): 3.5e-28, 65.3% identity in 124 aa overlap, and to Streptomyces coelicolor hypothetical [...]
ML1793 protein networkhttps://string-db.org/network/272631.gene:17575640Hypothetical protein.
ML1794 protein networkhttps://string-db.org/network/272631.gene:17575641Aminotransferase; Similar to M. tuberculosis predicted aminotransferase Rv2294 SW:YM94_MYCTU (Q50672) (407 aa); Fasta score E(): 0, 76.5% identity in 404 aa overlap, and to many others e.g. Esche [...]
hsp18 protein networkhttps://string-db.org/network/272631.gene:1757564218 KDA antigen (HSP 16.7); Not known. This protein is one of the major immune reactive proteins in mycobacteria.
ML1796 protein networkhttps://string-db.org/network/272631.gene:17575643Hypothetical protein; Previously sequenced as SW:Y15K_MYCLE (P13733) (137 aa); Fasta score E(): 0, 100.0% identity in 137 aa overlap; Similar to and.
ML1798 protein networkhttps://string-db.org/network/272631.gene:17575645Putative kinase; Similar to M. tuberculosis Rv1496 SW:YE96_MYCTU (P71777) (334 aa); Fasta score E(): 0, 83.0% identity in 323 aa overlap and to other members of the argK family e.g. SW:ARGK_ECOLI [...]
mutB protein networkhttps://string-db.org/network/272631.gene:17575646methylmalonyl-CoA mutase, [alpha] subunit; Similar to M. tuberculosis mutB SW:MUTB_MYCTU (P71774) (750 aa); Fasta score E(): 0, 88.9% identity in 748 aa overlap, and many other methylmalonyl-CoA [...]
mutA protein networkhttps://string-db.org/network/272631.gene:17575647methylmalonyl-CoA mutase, [beta] subunit; Similar to M. tuberculosis mutA SW:MUTA_MYCTU (P71773) (615 aa); Fasta score E(): 0, 75.3% identity in 636 aa overlap, and many other methylmalonyl-CoA m [...]
ML1802 protein networkhttps://string-db.org/network/272631.gene:17575649Conserved hypothetical protein; Similar to M. tuberculosis Rv1488 SW:YE88_MYCTU (P71768) (381 aa); Fasta score E(): 0, 89.8% identity in 373 aa overlap, and to many others members of the BAND 7 / [...]
ML1803 protein networkhttps://string-db.org/network/272631.gene:17575650Conserved hypothetical protein; Similar to M. tuberculosis Rv1487 TR:P71767 (EMBL:Z79701) (144 aa); Fasta score E(): 0, 74.8% identity in 143 aa overlap, and to many others e.g. Streptomyces coel [...]
ML1804 protein networkhttps://string-db.org/network/272631.gene:17575651Conserved hypothetical protein; Similar to M. tuberculosis Rv1486c SW:YE86_MYCTU (P71766) (302 aa); Fasta score E(): 5.1e-25, 76.7% identity in 300 aa overlap, and to Mycobacterium avium hypothet [...]
hemZ protein networkhttps://string-db.org/network/272631.gene:17575652Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
inhA protein networkhttps://string-db.org/network/272631.gene:17575653enoyl-[ACP] reductase; Similar to M. tuberculosis inhA Rv1484 SW:INHA_MYCTU (P46533) (269 aa); Fasta score E(): 0, 90.3% identity in 269 aa overlap, and to many others e.g. Escherichia coli enoyl [...]
fabG1 protein networkhttps://string-db.org/network/272631.gene:175756543-oxoacyl-[ACP] reductase (aka MabA); Similar to M. tuberculosis fabG Rv1483 SW:FABG_MYCTU (Q48930) (247 aa); Fasta score E(): 0, 68.6% identity in 245 aa overlap, and to many others e.g. Escheri [...]
ML1808 protein networkhttps://string-db.org/network/272631.gene:17575655Possible membrane protein; Similar to M. tuberculosis Rv1481 SW:YE81_MYCTU (P71762) (335 aa); Fasta score E(): 0, 91.0% identity in 335 aa overlap. Contains Pfam match to entry PF00092 vwa, von W [...]
ML1809 protein networkhttps://string-db.org/network/272631.gene:17575656Conserved hypothetical protein; Similar to M. tuberculosis Rv1480 SW:YE80_MYCTU (P71761) (317 aa); Fasta score E(): 0, 87.5% identity in 311 aa overlap. Contains Pfam match to entry PF01882 DUF58 [...]
moxR protein networkhttps://string-db.org/network/272631.gene:17575657MoxR homolog; Similar to M. tuberculosis moxR Rv1479 TR:O53170 (EMBL:AL021184) (377 aa); Fasta score E(): 0, 90.2% identity in 377 aa overlap, to many other moxR homologs and to e.g. Pyrococcus a [...]
ML1811 protein networkhttps://string-db.org/network/272631.gene:17575658Putative exported p60 protein homologue; Similar to M. tuberculosis Rv1478 TR:O53169 (EMBL:AL021184) (241 aa); Fasta score E(): 0, 77.1% identity in 240 aa overlap, and to Listeria innocua protei [...]
ML1812 protein networkhttps://string-db.org/network/272631.gene:17575659Putative exported p60 protein homologue; Similar to M. tuberculosis Rv1477 TR:O53168 (EMBL:AL021184) (472 aa); Fasta score E(): 0, 78.8% identity in 480 aa overlap and to Listeria innocua protein [...]
ML1813 protein networkhttps://string-db.org/network/272631.gene:17575660Similar to M. tuberculosis hypothetical protein Rv1476 TR:O53167 (EMBL:AL021184) (186 aa); Fasta score E(): 0, 78.7% identity in 178 aa overlap.
acn protein networkhttps://string-db.org/network/272631.gene:17575661Similar to M. tuberculosis aconitate hydratase Rv1475c TR:O53166 (EMBL:AL021184) (943 aa); Fasta score E(): 0, 86.8% identity in 948 aa overlap, and to many others e.g. Bacillus subtilis aconitat [...]
ML1816 protein networkhttps://string-db.org/network/272631.gene:17575663ABC transporter ATP-binding protein, possibly in EF-3 subfamily; Similar to M. tuberculosis Rv1473 TR:O53164 (EMBL:AL021184) (542 aa); Fasta score E(): 0, 87.9% identity in 545 aa overlap, and to [...]
trxB protein networkhttps://string-db.org/network/272631.gene:17575665Thioredoxin; Similar to M. tuberculosis thioredoxin trxB Rv1471 TR:O53162 (EMBL:AL021184) (123 aa); Fasta score E(): 2.4e-25, 65.4% identity in 107 aa overlap, and M. tuberculosis thioredoxin trx [...]
PPE-2 protein networkhttps://string-db.org/network/272631.gene:17575675PPE-family protein; Similar to Mycobacterium tuberculosis PPE-family proteins e.g. Rv0256c or MTV034.22C TR:O53678 (EMBL:AL021929) (556 aa) fasta scores: E(): 0, 63.5% id in 564 aa. Previously se [...]
ML1829 protein networkhttps://string-db.org/network/272631.gene:17575677Hypothetical protein; Unknown function.
mapA protein networkhttps://string-db.org/network/272631.gene:17575679Probable methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small an [...]
adk protein networkhttps://string-db.org/network/272631.gene:17575680Probable adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide [...]
secY protein networkhttps://string-db.org/network/272631.gene:17575681SecY subunit of preprotein translocase; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate a [...]
ML1835 protein networkhttps://string-db.org/network/272631.gene:17575683Similar to M. tuberculosis hypothetical protein Rv0730 TR:O53794 (EMBL:AL021958) (242 aa); Fasta score E(): 0, 83.5% identity in 218 aa overlap.
sppA protein networkhttps://string-db.org/network/272631.gene:17575687Similar to M. tuberculosis protease IV, signal peptide peptidase Rv0724, TR:P95072 (EMBL:Z84395) (623 aa); Fasta score E(): 0, 80.2% identity in 602 aa overlap, and to many others e.g. Escherichi [...]
rplO protein networkhttps://string-db.org/network/272631.gene:1757568850S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
rpmD protein networkhttps://string-db.org/network/272631.gene:17575689Similar to M. tuberculosis 50S ribosomal protein L30 Rv0722 SW:RL30_MYCTU (Z84395) (65 aa); Fasta score E(): 1.1e-21, 89.2% identity in 65 aa overlap. Contains Pfam match to entry PF00327 Ribosom [...]
rpsE protein networkhttps://string-db.org/network/272631.gene:1757569030S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
rplR protein networkhttps://string-db.org/network/272631.gene:1757569150S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protubera [...]
rplF protein networkhttps://string-db.org/network/272631.gene:1757569250S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the t [...]
rpsH protein networkhttps://string-db.org/network/272631.gene:1757569330S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to [...]
rpsN protein networkhttps://string-db.org/network/272631.gene:1757569430S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
rplE protein networkhttps://string-db.org/network/272631.gene:1757569550S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [...]
rplX protein networkhttps://string-db.org/network/272631.gene:1757569650S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rplN protein networkhttps://string-db.org/network/272631.gene:1757569750S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rpsQ protein networkhttps://string-db.org/network/272631.gene:1757570230S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rpmC protein networkhttps://string-db.org/network/272631.gene:17575703Similar to M. tuberculosis 50S ribosomal protein L29 Rv0709 SW:RL29_MYCTU (P95057) (77 aa); Fasta score E(): 2.5e-25, 91.9% identity in 74 aa overlap. Contains Pfam match to entry PF00831 Ribosom [...]
rplP protein networkhttps://string-db.org/network/272631.gene:1757570450S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpsC protein networkhttps://string-db.org/network/272631.gene:1757570530S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplV protein networkhttps://string-db.org/network/272631.gene:1757570650S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50 [...]
rpsS protein networkhttps://string-db.org/network/272631.gene:1757570730S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplB protein networkhttps://string-db.org/network/272631.gene:1757570850S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rplW protein networkhttps://string-db.org/network/272631.gene:1757570950S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main dock [...]
rplD protein networkhttps://string-db.org/network/272631.gene:1757571050S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes [...]
rplC protein networkhttps://string-db.org/network/272631.gene:1757571150S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal rib [...]
rpsJ protein networkhttps://string-db.org/network/272631.gene:1757571230S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
tuf protein networkhttps://string-db.org/network/272631.gene:17575725Elongation factor EF-Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
fusA protein networkhttps://string-db.org/network/272631.gene:17575726Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- [...]
rpsG protein networkhttps://string-db.org/network/272631.gene:1757572730S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit inte [...]
rpsL protein networkhttps://string-db.org/network/272631.gene:1757572830S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
ML1889 protein networkhttps://string-db.org/network/272631.gene:17575737Putataive endonuclease IV (apurinase); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'- [...]
rpoC protein networkhttps://string-db.org/network/272631.gene:17575738[beta]' subunit of RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/272631.gene:17575739[beta] subunit of RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
ML1892 protein networkhttps://string-db.org/network/272631.gene:17575740ABC transporter ATP-binding protein; Not known, could be involved in the transport of ribonucleotides.
rplL protein networkhttps://string-db.org/network/272631.gene:1757574350S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the ba [...]
rplJ protein networkhttps://string-db.org/network/272631.gene:1757574450S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal prot [...]
ML1898 protein networkhttps://string-db.org/network/272631.gene:17575746Similar to M. tuberculosis conserved hypothetical protein Rv0647c SW:Y647_MYCTU (P96936) (488 aa); Fasta score E(): 0, 85.3% identity in 448 aa overlap, and to others e.g. Synechocystis sp. SW:YH [...]
lipG protein networkhttps://string-db.org/network/272631.gene:17575747Probable hydrolase; Similar to M. tuberculosis putative hydrolase Rv0646c TR:P96935 (EMBL:Z92772) (301 aa); Fasta score E(): 0, 71.3% identity in 303 aa overlap, and to others e.g. Escherichia co [...]
mmaA1 protein networkhttps://string-db.org/network/272631.gene:17575748Similar to M. tuberculosis methyl mycolic acid synthase 1 Rv0645C TR:P94922 (EMBL:U77466) (286 aa); Fasta score E(): 0, 87.4% identity in 286 aa overlap, and to many others e.g. M. tuberculosis c [...]
mmaA4 protein networkhttps://string-db.org/network/272631.gene:17575751Similar to M. tuberculosis methyl mycolic acid synthase 4 Rv0642C TR:P72028 (EMBL:U66108) (301 aa); Fasta score E(): 0, 87.5% identity in 296 aa overlap, and to many others e.g. M. tuberculosis c [...]
rplA protein networkhttps://string-db.org/network/272631.gene:1757575250S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/272631.gene:1757575350S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/272631.gene:17575754Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination.
secE protein networkhttps://string-db.org/network/272631.gene:17575755SecE preprotein translocase; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
ML1908 protein networkhttps://string-db.org/network/272631.gene:17575757Similar to M. tuberculosis hypothetical protein Rv0637 TR:P96928 (EMBL:Z92772) (166 aa); Fasta score E(): 0, 88.6% identity in 166 aa overlap, and to others e.g. Streptomyces coelicolor SCD82.07 [...]
ML1909 protein networkhttps://string-db.org/network/272631.gene:17575758Similar to M. tuberculosis hypothetical protein Rv0636 TR:P96927 (EMBL:Z92772) (142 aa); Fasta score E(): 0, 93.0% identity in 142 aa overlap. Contains Pfam match to entry PF01575 MaoC_dehydratas [...]
ML1910 protein networkhttps://string-db.org/network/272631.gene:17575759Similar to Mycobacterium tuberculosis hypothetical proteins e.g. Rv0635 or MTCY20H10.16 TR:P96926 (EMBL:Z92772) (158 aa) fasta scores: E(): 0, 84.9% id in 159 aa. Also similar to Streptomyces coe [...]
rpmG2 protein networkhttps://string-db.org/network/272631.gene:17575760Similar to M. tuberculosis 50S ribosomal protein L33 type 2 SW:R332_MYCTU (P96925) (55 aa); Fasta score E(): 5.5e-24, 92.7% identity in 55 aa overlap. Contains PS00582 Ribosomal protein L33 signa [...]
ML1911A protein networkhttps://string-db.org/network/272631.gene:17575763Conserved hypothetical protein; Orthologous to M. tuberculosis Rv0634A but may be pseudogene as Rv0634A is predicted to be 13 aa longer. Also similar to M. tuberculosis Rv1560, sp|Q10771|YF60_MYC [...]
ML1912 protein networkhttps://string-db.org/network/272631.gene:17575764Putative glyoxylase II; Similar to M. tuberculosis putative glyoxylase II Rv0634c, to hypothetical proteins belonging to the glyoxalase II family e.g. Escherichia coli SW:YCBL_ECOLI (P75849) (215 [...]
ML1918 protein networkhttps://string-db.org/network/272631.gene:17575770Similar to M. tuberculosis hypothetical protein Rv3587c TR:O53572 (EMBL:AL022075) (264 aa); Fasta score E(): 0, 77.5% identity in 267 aa overlap. Contains probable transmembrane domain.
ML1919 protein networkhttps://string-db.org/network/272631.gene:17575771Putative carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
mutY protein networkhttps://string-db.org/network/272631.gene:17575772Similar to M. tuberculosis probable DNA glycosylase Rv3589 TR:O53574 (EMBL:AL022075) (304 aa); Fasta score E(): 0, 74.9% identity in 303 aa overlap, and to many others e.g. Escherichia coli A/G-s [...]
ML1921 protein networkhttps://string-db.org/network/272631.gene:17575773Similar to M. tuberculosis conserved hypothetical protein Rv3591c TR:O06157 (EMBL:Z95555) (257 aa); Fasta score E(): 0, 79.0% identity in 248 aa overlap; Similar to and ML2269.
ML1922 protein networkhttps://string-db.org/network/272631.gene:17575774Similar to M. tuberculosis conserved hypothetical protein Rv3592 TR:O06156 (EMBL:Z95555) (105 aa); Fasta score E(): 0, 84.6% identity in 104 aa overlap, and to others e.g. Bacillus subtilis hypot [...]
lpqF protein networkhttps://string-db.org/network/272631.gene:17575775Probale secreted protein; Similar to M. tuberculosis lipoprotein Rv3593 lpqF TR:O06155 (EMBL:Z95555) (452 aa); Fasta score E(): 0, 79.2% identity in 451 aa overlap, and weakly to several beta-lac [...]
sodC protein networkhttps://string-db.org/network/272631.gene:17575777Superoxide dismutase precursor (Cu-Zn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial surviva [...]
ML1926 protein networkhttps://string-db.org/network/272631.gene:17575778Similar to M. tuberculosis tuberculin related peptide (AT103) Rv0431 TR:P96277 (EMBL:Z84724) (164 aa); Fasta score E(): 1.6e-32, 67.5% identity in 163 aa overlap and TR:O69619 (EMBL:D00815) (172 [...]
ML1927 protein networkhttps://string-db.org/network/272631.gene:17575779Similar to M. tuberculosis hypothetical protein Rv0430 TR:P96276 (EMBL:Z84724) (102 aa); Fasta score E(): 0, 93.1% identity in 102 aa overlap, and to Streptomyces coelicolor hypothetical protein [...]
ML1928 protein networkhttps://string-db.org/network/272631.gene:17575780Hypothetical protein; Unknown function.
def protein networkhttps://string-db.org/network/272631.gene:17575781Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine i [...]
ML1936 protein networkhttps://string-db.org/network/272631.gene:17575788Conserved hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
ML1937 protein networkhttps://string-db.org/network/272631.gene:17575789Probable integral membrane protein; Similar to M. tuberculosis hypothetical protein Rv1111c TR:O86351 (EMBL:AL021897) (304 aa); Fasta score E(): 5.6e-31, 45.7% identity in 374 aa overlap. The N-t [...]
lytB2 protein networkhttps://string-db.org/network/272631.gene:17575790LytB homolog; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the [...]
ML1939 protein networkhttps://string-db.org/network/272631.gene:17575791Similar to M. tuberculosis hypothetical protein Rv1109c.
xseA protein networkhttps://string-db.org/network/272631.gene:17575792Exonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; [...]
xseB protein networkhttps://string-db.org/network/272631.gene:17575793Exonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; [...]
ML1942 protein networkhttps://string-db.org/network/272631.gene:17575794Similar to M. tuberculosis cholesterol dehydrogenase Rv1106c TR:O53454 (EMBL:AL021897) (370 aa); Fasta score E(): 0, 75.5% identity in 375 aa overlap, and to Nocardia sp NAD(P)-dependent choleste [...]
ML1945 protein networkhttps://string-db.org/network/272631.gene:17575797Similar to M. tuberculosis conserved hypothetical protein Rv1100 TR:O53448 (EMBL:AL021897) (233 aa); Fasta score E(): 0, 63.8% identity in 257 aa overlap.
ML1946 protein networkhttps://string-db.org/network/272631.gene:17575798Conserved hypothetical protein; Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate.
fum protein networkhttps://string-db.org/network/272631.gene:17575799Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
ML1949 protein networkhttps://string-db.org/network/272631.gene:17575801Hypothetical protein.
ML1950 protein networkhttps://string-db.org/network/272631.gene:17575802Similar to M. tuberculosis carbohydrate degrading enzyme Rv1096 TR:O53444 (EMBL:AL021897) (291 aa); Fasta score E(): 0, 81.3% identity in 289 aa overlap, and to others e.g. Streptomyces lividans [...]
phoH2 protein networkhttps://string-db.org/network/272631.gene:17575803PhoH-like protein; Similar to M. tuberculosis PhoH-like protein phoH2 Rv1095 TR:O53443 (EMBL:AL021897) (433 aa); Fasta score E(): 0, 92.8% identity in 432 aa overlap, and to others e.g. Escherich [...]
desA2 protein networkhttps://string-db.org/network/272631.gene:17575804Similar to M. tuberculosis acyl-[ACP] desaturase desA2 TR:O53442 (EMBL:AL021897) (275 aa); Fasta score E(): 0, 78.1% identity in 274 aa overlap, and to others e.g. Gossypium hirsutum (Upland cott [...]
glyA protein networkhttps://string-db.org/network/272631.gene:17575805Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
coaA protein networkhttps://string-db.org/network/272631.gene:17575806Pantothenate kinase; Similar to M. tuberculosis pantothenate kinase coaA Rv1092c SW:COAA_MYCTU (O53440) (312 aa); Fasta score E(): 0, 93.6% identity in 312 aa overlap, and to many others e.g. Esc [...]
truA protein networkhttps://string-db.org/network/272631.gene:17575807Probable pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
rplQ protein networkhttps://string-db.org/network/272631.gene:17575808Similar to M. tuberculosis 50S ribosomal protein L17 rplQ Rv3456c SW:RL17_MYCTU (O06323) (180 aa); Fasta score E(): 0, 81.9% identity in 171 aa overlap. Contains Pfam match to entry PF01196 Ribos [...]
rpoA protein networkhttps://string-db.org/network/272631.gene:17575809[alpha] subunit of RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpsD protein networkhttps://string-db.org/network/272631.gene:1757581030S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpsK protein networkhttps://string-db.org/network/272631.gene:1757581130S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
rpsM protein networkhttps://string-db.org/network/272631.gene:1757581230S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 [...]
rpmJ protein networkhttps://string-db.org/network/272631.gene:17575813Similar to M. tuberculosis 50S ribosomal protein L36 rpmJ Rv3461c SW:RL36_MYCTU (P45810) (37 aa); Fasta score E(): 1e-15, 86.5% identity in 37 aa overlap. Contains PS00828 Ribosomal protein L36 s [...]
infA protein networkhttps://string-db.org/network/272631.gene:17575814Initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) s [...]
rmlB protein networkhttps://string-db.org/network/272631.gene:17575816Similar to M. tuberculosis dTDP-glucose 4,6-dehydratase rmlB Rv3464 TR:O06329 (EMBL:Z95390) (331 aa); Fasta score E(): 0, 84.0% identity in 331 aa overlap, and TR:Q50556 (EMBL:U43540) (329 aa); F [...]
rmlC protein networkhttps://string-db.org/network/272631.gene:17575817dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehy [...]
lpqH protein networkhttps://string-db.org/network/272631.gene:17575818Possible lipoprotein; Similar to M. tuberculosis 19 kDa lipoprotein antigen precursor lpqH Rv3763. Contains a possible N-terminal signal sequence and a PS00013 Prokaryotic membrane lipoprotein li [...]
ML1974 protein networkhttps://string-db.org/network/272631.gene:17575826Unknown permease; Similar to M. tuberculosis probable permease Rv1979c SW:YJ79_MYCTU (Q10875) (481 aa); Fasta score E(): 0, 76.8% identity in 462 aa overlap, and to e.g. Arabidopsis thaliana puta [...]
ML1976 protein networkhttps://string-db.org/network/272631.gene:17575828Very hypothetical protein; Unknown; questionable CDS.
ML1983 protein networkhttps://string-db.org/network/272631.gene:17575835Conserved hypothetical protein; Similar to M. tuberculosis gene with weak similarity to pollen antigens Rv1919c TR:O53961 (EMBL:AL022020) (154 aa); Fasta score E(): 0, 72.8% identity in 151 aa ov [...]
aceA protein networkhttps://string-db.org/network/272631.gene:17575837Isocitrate lyase; Involved in the persistence and virulence of Mycobacterium. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, w [...]
ctpA protein networkhttps://string-db.org/network/272631.gene:17575839Putative cation-transporting ATPase; Involved in copper export.
ML1988 protein networkhttps://string-db.org/network/272631.gene:17575840Similar to M. tuberculosis probable integral membrane protein Rv0093c SW:Y093_MYCTU (Q10890) E():0 70.3% id in 236 aa. Contains possible membrane spanning hydrophobic domains. Note lacks the N-te [...]
ML1989 protein networkhttps://string-db.org/network/272631.gene:17575841Hypothetical protein.
ML1990 protein networkhttps://string-db.org/network/272631.gene:17575842Putative integral membrane protein; No database matches. Contains possible membrane spanning hydrophobic domains.
PPE-3 protein networkhttps://string-db.org/network/272631.gene:17575843PPE-family protein; Similar to M. tuberculosis PPE-family protein Rv0096 SW:Y096_MYCTU (Q10892) (463 aa); Fasta score E(): 0, 58.6% identity in 466 aa overlap. Contains Pfam match to entry PF0082 [...]
ML1992 protein networkhttps://string-db.org/network/272631.gene:17575844Putative oxidoreductase; Similar to M. tuberculosis hypothetical protein Rv0097 SW:Y097_MYCTU (Q10893) (289 aa); Fasta score E(): 0, 76.4% identity in 288 aa overlap, and to Escherichia coli alph [...]
ML1993 protein networkhttps://string-db.org/network/272631.gene:17575845Conserved hypothetical protein; Similar to M. tuberculosis hypothetiacl protein RV0098 SW:Y098_MYCTU (Q10894) (183 aa); Fasta score E(): 0, 65.6% identity in 180 aa overlap.
fadD10 protein networkhttps://string-db.org/network/272631.gene:17575846acyl-CoA synthase; Similar to Mycobacterium tuberculosis putative acyl-CoA synthases e.g. Rv0099 or MTCY251.18 TR:Q10878 (EMBL:Z74410) (540 aa) fasta scores: E(): 0, 74.6% id in 531 aa. Previousl [...]
ML1995 protein networkhttps://string-db.org/network/272631.gene:17575847Similar to M. tuberculosis hypothetical protein Rv0100 SW:Y100_MYCTU (Q10895) (78 aa); Fasta score E(): 1.1e-18, 69.0% identity in 71 aa overlap. Contains Pfam match to entry PF00550 pp-binding, [...]
nrp protein networkhttps://string-db.org/network/272631.gene:17575848Probable peptide synthase; Similar in N-terminus to M. tuberculosis probable peptide synthetase nrp Rv0101 TR:Q10896 (EMBL:Z74410) (2512 aa); Fasta score E(): 0, 65.7% identity in 1089 aa overlap [...]
ML1997 protein networkhttps://string-db.org/network/272631.gene:17575849Similar to M. tuberculosis probable integral membrane protein Rv0970 SW:Y970_MYCTU (P71541) (210 aa); Fasta score E(): 0, 52.1% identity in 213 aa overlap, and to Streptomyces coelicolor putative [...]
ML1998 protein networkhttps://string-db.org/network/272631.gene:17575850Similar to M. tuberculosis membrane protein Rv0102 SW:Y102_MYCTU (Q10897) (661 aa); Fasta score E(): 0, 70.2% identity in 662 aa overlap. Contains multiple possible membrane spanning hydrophobic [...]
ctpB protein networkhttps://string-db.org/network/272631.gene:17575852Similar to M. tuberculosis cation-transporting ATPase ctpB SW:CTPB_MYCTU (Q10877) (752 aa); Fasta score E(): 0, 77.0% identity in 752 aa overlap, and to many others e.g. Bacillus subtilis potenti [...]
ML2010 protein networkhttps://string-db.org/network/272631.gene:17575862Putative lipoprotein; Similar to M. tuberculosis hypothetical protein Rv1906c TR:O07726 (EMBL:Z97193) (156 aa); Fasta score E(): 2.6e-31, 63.2% identity in 155 aa overlap. Contains a possible N-t [...]
aao protein networkhttps://string-db.org/network/272631.gene:17575863D-amino acid oxidase; Similar to M. tuberculosis putative D-amino acid oxidase aao Rv1905c TR:O07727 (EMBL:Z97193) (320 aa); Fasta score E(): 0, 71.4% identity in 318 aa overlap, and to many othe [...]
ML2012 protein networkhttps://string-db.org/network/272631.gene:17575864Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein Rv1903 or MTCY180.15C TR:O07729 (EMBL:Z97193) (134 aa) fasta scores: E(): 0, 80.6% id in 129 aa and to Strept [...]
ML2013 protein networkhttps://string-db.org/network/272631.gene:17575865Hypothetical protein; No database matches.
cinA protein networkhttps://string-db.org/network/272631.gene:17575867Similar to M. tuberculosis competence damage protein homolog cinA Rv1901 TR:O07731 (EMBL:Z97193) (430 aa); Fasta score E(): 0, 77.0% identity in 431 aa overlap, and to e.g. Streptococcus pneumoni [...]
ML2020 protein networkhttps://string-db.org/network/272631.gene:17575872Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
ML2022 protein networkhttps://string-db.org/network/272631.gene:17575874Similar to M. tuberculosis hypothetical protein Rv1893 TR:O07739 (EMBL:Z97193) (72 aa); Fasta score E(): 3e-13, 69.4% identity in 72 aa overlap.
ML2023 protein networkhttps://string-db.org/network/272631.gene:17575875Putative secreted protein; Similar to M. tuberculosis hypothetical protein Rv1891 TR:O07741 (EMBL:Z97193) (135 aa); Fasta score E(): 0, 79.7% identity in 133 aa overlap. Contains probable N-termi [...]
fbpB protein networkhttps://string-db.org/network/272631.gene:17575880Antigen 85A, mycolyltransferase; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates [...]
ML2030 protein networkhttps://string-db.org/network/272631.gene:17575882Similar to Mycobacterium tuberculosis hypothetical proteins: TR:O07747 (EMBL:Z97193) fasta scores: E(): 0, 70.2% in 141 aa and TR:P71755 (EMBL:Z81368) fasta scores: E(): 2.8e-20, 47.9% in 121 aa; [...]
ML2031 protein networkhttps://string-db.org/network/272631.gene:17575883Similar to Mycobacterium tuberculosis hypothetical protein TR:O07748 (EMBL:Z97193) fasta scores: E(): 0, 76.2% in 151 aa, and to Streptomyces actuosus NSH-OrfB TR:P72384 (EMBL:U75434) fasta score [...]
bfrA protein networkhttps://string-db.org/network/272631.gene:17575890Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation wit [...]
oxyR protein networkhttps://string-db.org/network/272631.gene:17575893Probable LysR-family transcriptional regulator; Required for the induction the katG gene for catalase. Involved in the response to hydrogen peroxide (By similarity).
ahpC protein networkhttps://string-db.org/network/272631.gene:17575894Alkyl hydroperoxide reductase; Similar to Mycobacterium avium alkyl hydroperoxidase C TR:Q57413 (EMBL:U18263) fasta scores: E(): 0, 86.2% in 195 aa, and to Streptomyces viridosporus alkyl hydrope [...]
ML2044 protein networkhttps://string-db.org/network/272631.gene:17575896Hypothetical protein; No database matches.
ML2045 protein networkhttps://string-db.org/network/272631.gene:17575897Hypothetical protein; No database matches.
lldD2 protein networkhttps://string-db.org/network/272631.gene:17575898L-lactate dehydrogenase; Similar to Mycobacterium tuberculosis LLDD2 TR:P95143 (EMBL:AQ102036) fasta scores: E(): 0, 85.0% in 413 aa, and to Escherichia coli L-lactate dehydrogenase SW:LLDD_ECOLI [...]
ML2048 protein networkhttps://string-db.org/network/272631.gene:17575900Similar to Mycobacterium tuberculosis hypothetical protein TR:P95144 (EMBL:AL204060) fasta scores: E(): 4.7e-16, 62.0% in 79 aa, and to Streptomyces coelicolor hypothetical protein TR:CAB88434 (E [...]
ML2053 protein networkhttps://string-db.org/network/272631.gene:17575905Putative alcohol dehydrogenase; Similar to Mycobacterium tuberculosis adhA or Rv1862 or MTCY359.11 TR:P95153 (EMBL:Z83859) (346 aa) fasta scores: E(): 0, 84.5% id in 336 aa. Similar to Rhizobium [...]
ML2054 protein networkhttps://string-db.org/network/272631.gene:17575906Integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein TR:P95154 (EMBL:Z83859) fasta scores: E(): 6.4e-18, 58.4% in 101 aa, and to Escherichia coli transglycosylase [...]
modD protein networkhttps://string-db.org/network/272631.gene:17575907Probable cell surface protein (associated with virulence); Previously sequenced Mycobacterium leprae Fap-l fibronectin attachment protein important in virulence for the efficient invasion of epit [...]
ML2059 protein networkhttps://string-db.org/network/272631.gene:17575911Short-chain dehydrogenase/reductase family; Similar to Mycobacterium tuberculosis hypothetical 23.2 kda protein TR:P95158 (EMBL:Z83859) fasta scores: E(): 0, 80.5% in 220 aa, and to Streptomyces [...]
ML2061 protein networkhttps://string-db.org/network/272631.gene:17575913Possible dehydrogenase; Similar to Mycobacterium tuberculosis hypothetical 49.6 kda protein TR:P95160 (EMBL:Z83859) fasta scores: E(): 0, 90.2% in 460 aa, and to Corynebacterium glutamicum NADH d [...]
ML2063 protein networkhttps://string-db.org/network/272631.gene:17575915Possible regulator; Similar to Mycobacterium tuberculosis hypothetical 15.2 kda protein TR:P95163 (EMBL:AL008609) fasta scores: E(): 0, 95.1% in 123 aa, and weakly to Bacillus licheniformis penic [...]
ML2064 protein networkhttps://string-db.org/network/272631.gene:17575916Integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical 32.7 kda protein TR:P95164 (EMBL:Z83859) fasta scores: E(): 0, 87.6% in 314 aa, and to Streptomyces coelicolor putati [...]
gnd protein networkhttps://string-db.org/network/272631.gene:175759176-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
guaB1 protein networkhttps://string-db.org/network/272631.gene:17575918Inosine-5'-monophosphate dehydrogenase; Previously sequenced as TR:O32912 (EMBL:AL008609) fasta scores: E(): 0, 100.0% in 478 aa. Similar to Mycobacterium tuberculosis inosine-5'-monophosphate de [...]
glcB protein networkhttps://string-db.org/network/272631.gene:17575921Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to t [...]
ML2070 protein networkhttps://string-db.org/network/272631.gene:17575922Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 69.7 kda protein Rv1836c SW:YI36_MYCTU (Q50597) fasta scores: E(): 0, 66.0% in 714 aa.
gcvB protein networkhttps://string-db.org/network/272631.gene:17575924Glycine decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is re [...]
ML2073 protein networkhttps://string-db.org/network/272631.gene:17575925Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 24.0 kda protein Rv1830 SW:YI30_MYCTU (Q50603) fasta scores: E(): 0, 90.0% in 231 aa, and to Streptomyces coelic [...]
ML2074 protein networkhttps://string-db.org/network/272631.gene:17575926Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 18.1 kda protein Rv1829 SW:YI29_MYCTU (Q50604) fasta scores: E(): 0, 95.1% in 164 aa, and to Streptomyces coelic [...]
ML2075 protein networkhttps://string-db.org/network/272631.gene:17575927Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 26.4 kda protein Rv1828 SW:YI28_MYCTU (Q50605) fasta scores: E(): 0, 87.6% in 251 aa, and to Streptomyces coelic [...]
ML2076 protein networkhttps://string-db.org/network/272631.gene:17575928Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 17.3 kda protein Rv1827 SW:YI27_MYCTU (Q50606) fasta scores: E(): 0, 87.0% in 161 aa, and to Streptomyces coelic [...]
gcvH protein networkhttps://string-db.org/network/272631.gene:17575929Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
pgsA2 protein networkhttps://string-db.org/network/272631.gene:17575933CDP-diacylglycerol-glycerol-3-phosphate; Similar to Mycobacterium tuberculosis putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase SW:PGSA_MYCTU (Q50611) fasta scores: E( [...]
secA2 protein networkhttps://string-db.org/network/272631.gene:17575934SecA, preprotein translocase subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to [...]
ilvG protein networkhttps://string-db.org/network/272631.gene:17575935Acetolactate synthase II; Similar to Mycobacterium tuberculosis probable acetolactate synthase SW:ILVG_MYCTU (Q50613) fasta scores: E(): 0, 86.1% in 548 aa, and to Bacillus subtilis acetolactate [...]
ML2084 protein networkhttps://string-db.org/network/272631.gene:17575936Probable multidrug resistance pump; Similar to Mycobacterium tuberculosis hypothetical ABC transporter ATP-binding protein Rv1819c SW:YI19_MYCTU (Q50614) fasta scores: E(): 0, 74.9% in 634 aa, an [...]
ML2088 protein networkhttps://string-db.org/network/272631.gene:17575940Putative cytochrome p450; Similar to Streptomyces coelicolor putative cytochrome p-450 hydroxylase TR:Q9X8Q3 (EMBL:AL049754) fasta scores: E(): 0, 37.4% in 401 aa, and to Mycobacterium tuberculos [...]
pstA1 protein networkhttps://string-db.org/network/272631.gene:17575945Membrane-bound component of phosphate transport; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membr [...]
pstC2 protein networkhttps://string-db.org/network/272631.gene:17575946Membrane-bound component of phosphate transport; Part of a binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membran [...]
phoS2 protein networkhttps://string-db.org/network/272631.gene:17575947PstS component of phosphate uptake; Part of the ABC transporter complex PstSACB involved in phosphate import.
mntH protein networkhttps://string-db.org/network/272631.gene:17575950Probable manganese transport protein; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
ML2113 protein networkhttps://string-db.org/network/272631.gene:17575966Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 15.8 kda protein TR:O05902 (EMBL:Z95210) fasta scores: E(): 0, 83.9% in 143 aa, and to Mycobacterium tuberculosi [...]
ML2114 protein networkhttps://string-db.org/network/272631.gene:17575967Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 6.4 kda protein TR:O05901 (EMBL:Z95210) fasta scores: E(): 1.8e-07, 61.9% in 42 aa, and to Streptomyces coelicol [...]
echA6 protein networkhttps://string-db.org/network/272631.gene:17575971enoyl-CoA hydratase/isomerase superfamily member; Could possibly oxidize fatty acids using specific components.
ML2123 protein networkhttps://string-db.org/network/272631.gene:17575976Two-component response regulator; Member of the two-component regulatory system PrrB/PrrA that is involved specifically in early intracellular multiplication of Mycobacterium and is essential for [...]
ML2124 protein networkhttps://string-db.org/network/272631.gene:17575977Sensor histidine kinase; Member of the two-component regulatory system PrrB/PrrA that is involved specifically in early intracellular multiplication of Mycobacterium and is essential for its viab [...]
gltA2 protein networkhttps://string-db.org/network/272631.gene:17575983Citrate synthase 1; Similar to Mycobacterium tuberculosis citrate synthase 1 SW:CISY_MYCTU (Q10530) fasta scores: E(): 0, 91.0% in 431 aa, and to Corynebacterium glutamicum citrate synthase SW:CI [...]
pdxH protein networkhttps://string-db.org/network/272631.gene:17575984Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
fprB protein networkhttps://string-db.org/network/272631.gene:17575987Ferredoxin, ferredoxin-NADP reductase; Similar to Mycobacterium tuberculosis probable ferredoxin/ferredoxin--NADP reductase SW:FPRB_MYCTU (Q10547) fasta scores: E(): 0, 76.6% in 560 aa, and to Ho [...]
ML2135 protein networkhttps://string-db.org/network/272631.gene:17575988Possible transmembrane protein; Similar to Mycobacterium tuberculosis hypothetical 39.8 kda protein rv0885 SW:Y885_MYCTU (Q10546) fasta scores: E(): 0, 83.9% in 341 aa, and to Streptomyces coelic [...]
serC protein networkhttps://string-db.org/network/272631.gene:17575989Putative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreoni [...]
ML2137 protein networkhttps://string-db.org/network/272631.gene:17575990Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 27.4 kda protein rv0883c SW:Y883_MYCTU (Q10545) fasta scores: E(): 0, 79.4% in 253 aa, and to Streptomyces coeli [...]
ML2140 protein networkhttps://string-db.org/network/272631.gene:17575993Putative MarR-family protein; Similar to Mycobacterium tuberculosis hypothetical 15.6 kda protein Rv0880 SW:Y880_MYCTU (Q10542) fasta scores: E(): 0, 90.2% in 143 aa, and to Streptomyces coelicol [...]
ML2141 protein networkhttps://string-db.org/network/272631.gene:17575994Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 9.5 kda protein Rv0879c SW:Y879_MYCTU (Q10541) fasta scores: E(): 6.6e-25, 76.9% in 91 aa.
ML2142 protein networkhttps://string-db.org/network/272631.gene:17575995Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 27.5 kda protein rv0877 SW:Y877_MYCTU (Q10539) fasta scores: E(): 0, 80.5% in 257 aa, and to Streptomyces coelic [...]
ML2143 protein networkhttps://string-db.org/network/272631.gene:17575996Possible membrane protein; Similar to Mycobacterium tuberculosis hypothetical 57.9 kda protein rv0876c SW:Y876_MYCTU (Q10564) fasta scores: E(): 0, 81.2% in 568 aa, and to Streptomyces coelicolor [...]
ML2144 protein networkhttps://string-db.org/network/272631.gene:17575997Possible exported protein; Similar to Mycobacterium tuberculosis hypothetical 17.8 kda protein Rv0875c precursor SW:Y875_MYCTU (Q10537) fasta scores: E(): 0, 73.5% in 155 aa. Contains a possible [...]
cspB protein networkhttps://string-db.org/network/272631.gene:17576000Similar to Mycobacterium tuberculosis cold shock protein b TR:O53883 (EMBL:AL022004) fasta scores: E(): 0, 86.0% in 136 aa, and to Bacillus cereus cold shock-like protein cspc SW:CSPC_BACCE (Q450 [...]
ML2151 protein networkhttps://string-db.org/network/272631.gene:17576004Conserved hypothetical protein; Similar to C-terminus of Mycobacterium tuberculosis hypothetical 40.0 kda protein TR:O53879 (EMBL:AL022004) fasta scores: E(): 4.8e-29, 63.0% in 200 aa. Contains N [...]
ML2155 protein networkhttps://string-db.org/network/272631.gene:17576008Conserved hypothetical protein; Similar to C-terminus of Mycobacterium tuberculosis hypothetical 10.1 kda protein TR:O53875 (EMBL:AL022004) fasta scores: E(): 1.5e-21, 74.0% in 73 aa.
ML2156 protein networkhttps://string-db.org/network/272631.gene:17576009Possible DNA-binding protein; Similar to Mycobacterium tuberculosis hypothetical 79.7 kda protein TR:O53874 (EMBL:AL022004) fasta scores: E(): 0, 77.6% in 753 aa, and to Streptomyces coelicolor h [...]
ML2157 protein networkhttps://string-db.org/network/272631.gene:17576010Probable DNA helicase; Similar to Mycobacterium tuberculosis putative DNA helicase TR:O53873 (EMBL:AL022004) fasta scores: E(): 0, 91.1% in 542 aa, and to Saccharomyces cerevisiae DNA repair heli [...]
ML2158 protein networkhttps://string-db.org/network/272631.gene:17576011Hypothetical protein; No database matches.
fadB protein networkhttps://string-db.org/network/272631.gene:17576014Putative fatty oxidation complex alpha subunit; Similar to Mycobacterium tuberculosis hypothetical 76.1 kda protein TR:O53872 (EMBL:AL022004) fasta scores: E(): 0, 88.6% in 719 aa, and to Escheri [...]
fadA protein networkhttps://string-db.org/network/272631.gene:17576015Similar to Mycobacterium tuberculosis putative beta-ketoadipyl CoA thiolase TR:O53871 (EMBL:AL022004) fasta scores: E(): 0, 94.5% in 403 aa, and to Escherichia coli acetyl-coa acetyltransferase T [...]
pdc protein networkhttps://string-db.org/network/272631.gene:17576020Pyruvate (or indolepyruvate) decarboxylase; Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.
ML2170 protein networkhttps://string-db.org/network/272631.gene:17576023Hypothetical protein; No database matches.
ML2172 protein networkhttps://string-db.org/network/272631.gene:17576025Hypothetical protein; No database matches.
cdd protein networkhttps://string-db.org/network/272631.gene:17576027Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
ML2177 protein networkhttps://string-db.org/network/272631.gene:17576030Similar to Mus musculus uridine phosphorylase SW:UDP_MOUSE () fasta scores: E(): 1.9e-21, 34.0% in 268 aa, and to Homo sapiens uridine phosphorylase SW:UDP_HUMAN () fasta scores: E(): 2.2e-19, 32 [...]
ML2178 protein networkhttps://string-db.org/network/272631.gene:17576031Hypothetical protein; No database matches.
desA1 protein networkhttps://string-db.org/network/272631.gene:17576042acyl-[ACP] desaturase; Similar to Mycobacterium tuberculosis protein desA1 TR:Q50824 (EMBL:U49839) fasta scores: E(): 0, 79.9% in 338 aa, and to Oryza sativa acyl-[acyl-carrier protein] desaturas [...]
ML2186 protein networkhttps://string-db.org/network/272631.gene:17576043Transcriptional regulator (NifR3/Smm1 family); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in [...]
phoY1 protein networkhttps://string-db.org/network/272631.gene:17576045Phosphate transport system regulator; Plays a role in the regulation of phosphate uptake.
phoT protein networkhttps://string-db.org/network/272631.gene:17576046Phosphate transport system ABC transporter; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC t [...]
phoS3 protein networkhttps://string-db.org/network/272631.gene:17576049Phosphate-binding protein 3 precursor; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
ML2193 protein networkhttps://string-db.org/network/272631.gene:17576050Putative acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
ML2195 protein networkhttps://string-db.org/network/272631.gene:17576052Probable exported protein; Similar to Mycobacterium tuberculosis hypothetical 28.6 kda protein TR:O53829 (EMBL:AL022004) fasta scores: E(): 0, 73.0% in 270 aa. Contains a possible N-terminal sign [...]
thiX protein networkhttps://string-db.org/network/272631.gene:17576053Thiredoxin; Similar to Mycobacterium tuberculosis putative thioredoxin TR:O53828 (EMBL:AL022004) fasta scores: E(): 1.1e-30, 63.8% in 141 aa, and to Anacystis nidulans thioredoxin 1 SW:THI1_ANANI [...]
ML2197 protein networkhttps://string-db.org/network/272631.gene:17576054Integral membrane protein; Similar to Saccharopolyspora erythraea hypothetical 16.0 kda protein TR:Q54082 (EMBL:M29612) fasta scores: E(): 4.9e-15, 43.9% in 139 aa. Contains possible membrane spa [...]
cysA3 protein networkhttps://string-db.org/network/272631.gene:17576055Thiosulfate sulfurtransferase; May be a sulfotransferase involved in the formation of thiosulfate.
ML2199 protein networkhttps://string-db.org/network/272631.gene:17576056Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 10.2 kda protein TR:O05794 (EMBL:Z95150) fasta scores: E(): 6.5e-33, 84.0% in 100 aa, and to Saccharopolyspora e [...]
ML2200 protein networkhttps://string-db.org/network/272631.gene:17576057Conserved hypothetical protein; May play a role in the intracellular transport of hydrophobic ligands.
ML2203 protein networkhttps://string-db.org/network/272631.gene:17576060Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 39.4 kda protein RV0811C TR:O53825 (EMBL:AL022004) fasta scores: E(): 0, 77.4% id in 367 aa, and to Corynebacter [...]
ML2204 protein networkhttps://string-db.org/network/272631.gene:17576061Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 6.9 kda protein RV0810C TR:O53824 (EMBL:AL022004) fasta scores: E(): 9.9e-17, 77.8% id in 63 aa, and to Streptom [...]
purM protein networkhttps://string-db.org/network/272631.gene:17576062Similar to Mycobacterium tuberculosis 5'-phosphoribosyl-5-aminoimidazole synthetase RV0809 TR:O53823 (EMBL:AL022004) fasta scores: E(): 0, 87.1% id in 364 aa, and to Bacillus subtilis phosphoribo [...]
purF protein networkhttps://string-db.org/network/272631.gene:17576063Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
ML2207 protein networkhttps://string-db.org/network/272631.gene:17576064Similar to Mycobacterium tuberculosis hypothetical protein Rv0807 or MTCY07H7A.02C TR:O06627 (EMBL:Z95618) (129 aa) fasta scores: E(): 0, 73.4% id in 128 aa. Similar to Corynebacterium ammoniagen [...]
cpsY protein networkhttps://string-db.org/network/272631.gene:17576066Probable UDP-glucose-4-epimerase; Similar to Mycobacterium tuberculosis hypothetical 60.3 kda protein RV0806C TR:O06628 (EMBL:Z95618) fasta scores: E(): 0, 82.3% id in 530 aa, and to Neisseria me [...]
ML2210 protein networkhttps://string-db.org/network/272631.gene:17576067Conserved hypothetical protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
purL protein networkhttps://string-db.org/network/272631.gene:17576068Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion [...]
pepC protein networkhttps://string-db.org/network/272631.gene:17576070Similar to Mycobacterium tuberculosis hypothetical 46.0 kda protein RV0800 OR MTCY07H7A.09C TR:O06634 (EMBL:Z95618) fasta scores: E(): 0, 78.3% id in 433 aa, and to Saccharomyces cerevisiae vacuo [...]
purQ protein networkhttps://string-db.org/network/272631.gene:17576076Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion o [...]
ML2219A protein networkhttps://string-db.org/network/272631.gene:17576077Conserved hypothetical protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycin [...]
ptrB protein networkhttps://string-db.org/network/272631.gene:17576084Protease II; Similar to Mycobacterium tuberculosis hypothetical 60.9 kda protein cy369.26 RV0782 OR MTCY369.26 TR:P71835 (EMBL:Z80226) fasta scores: E(): 0, 77.8% id in 519 aa, and to Escherichia [...]
purC protein networkhttps://string-db.org/network/272631.gene:17576085Similar to Mycobacterium tuberculosis phosphoribosylaminoimidazole-succinocarboxamide synthase PURC OR RV0780 OR MTCY369.24 SW:PUR7_MYCTU (Q59566; P77904) fasta scores: E(): 0, 81.5% id in 297 aa [...]
ML2228 protein networkhttps://string-db.org/network/272631.gene:17576086Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 21.6 kda protein cy369.23c precursor RV0779C OR MTCY369.23C TR:P71833 (EMBL:Z80226) fasta scores: E(): 0, 67.2% [...]
purB protein networkhttps://string-db.org/network/272631.gene:17576088Adenylosuccinate lyase; Similar to Mycobacterium tuberculosis hypothetical 51.0 kda protein cy369.21b RV0777 OR MTCY369.21B TR:P71832 (EMBL:Z80226) fasta scores: E(): 0, 86.4% id in 472 aa, and t [...]
purD protein networkhttps://string-db.org/network/272631.gene:17576093Phosphoribosylamine-glycine ligase; Similar to Mycobacterium tuberculosis phosphoribosylamine--glycine ligase PurD OR RV0772 OR MTCY369.17 SW:PUR2_MYCTU (P71827) fasta scores: E(): 0, 81.8% id in [...]
ML2237 protein networkhttps://string-db.org/network/272631.gene:17576095Conserved hypothetical protein (HIT family); Similar to Mycobacterium leprae hypothetical 14.7 kda protein MLCB5.04C TR:Q9R734 (EMBL:Z95151) fasta scores: E(): 0, 100.0% id in 134 aa, and to Borr [...]
ML2242 protein networkhttps://string-db.org/network/272631.gene:17576101Conserved hypothetical protein; Similar to Mycobacterium fortuitum plasmid pAL5000 hypothetical 26.6 kda protein TR:Q52145 (EMBL:M23557) fasta scores: E(): 9.9e-05, 27.2% id in 250 aa.
ML2244 protein networkhttps://string-db.org/network/272631.gene:17576103Hypothetical protein; No database matches.
cpsA protein networkhttps://string-db.org/network/272631.gene:17576106Conserved hypothetical protein; Similar to Mycobacterium tuberculosis cpsa CPSA OR RV3484 OR MTCY13E12.37 TR:O06347 (EMBL:Z95390) fasta scores: E(): 0, 74.9% id in 518 aa, and to Streptococcus ag [...]
ML2252 protein networkhttps://string-db.org/network/272631.gene:17576111Hypothetical protein; No database matches.
ML2253 protein networkhttps://string-db.org/network/272631.gene:17576112Antigen 84 homolog; Similar to Mycobacterium tuberculosis antigen 84 AG84 OR WAG31 OR RV2145C OR MTCY270.23 SW:AG84_MYCTU (P46816) fasta scores: E(): 2.2e-05, 50.0% id in 54 aa, and to Mycobacter [...]
otsA protein networkhttps://string-db.org/network/272631.gene:17576113Probable trehalose-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose and in the production of glycogen and alpha-glucan via the TreS-Pep2 branch involv [...]
menE protein networkhttps://string-db.org/network/272631.gene:17576116O-succinylbenzoic acid-CoA ligase; Similar to Mycobacterium tuberculosis MenE or RV0542C or MTCY25D10.21C TR:O06408 (EMBL:Z95558) fasta scores: E(): 0, 78.3% id in 359 aa, and to Escherichia coli [...]
ML2258 protein networkhttps://string-db.org/network/272631.gene:17576117Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 11.3 kda protein RV0543C OR MTCY25D10.22C TR:O06409 (EMBL:Z95558) fasta scores: E(): 1.4e-27, 73.5% id in 98 aa, [...]
ML2259 protein networkhttps://string-db.org/network/272631.gene:17576118Possible membrane protein; Similar to Mycobacterium tuberculosis hypothetical 9.7 kda protein RV0544C OR MTCY25D10.23C TR:O06410 (EMBL:Z95558) fasta scores: E(): 3.3e-22, 64.6% id in 96 aa. Conta [...]
pitA protein networkhttps://string-db.org/network/272631.gene:17576119Low-affinity inorganic phosphate transporter; Low-affinity inorganic phosphate transport; Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
ML2261 protein networkhttps://string-db.org/network/272631.gene:17576120Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 14.3 kda protein RV0546C OR MTCY25D10.25C TR:O06412 (EMBL:Z95558) fasta scores: E(): 0, 84.7% id in 131 aa. Also [...]
menB protein networkhttps://string-db.org/network/272631.gene:17576122Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
ML2264 protein networkhttps://string-db.org/network/272631.gene:17576123Hypothetical protein; Unknown function.
ML2265 protein networkhttps://string-db.org/network/272631.gene:17576124Hypothetical protein; Unknown function.
ML2268 protein networkhttps://string-db.org/network/272631.gene:17576127Putative isomerase/racemase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
ML2269 protein networkhttps://string-db.org/network/272631.gene:17576128Putative hydrolase; Similar to Mycobacterium tuberculosis hypothetical protein Rv0554 or MTCY25D10.33 TR:O06420 (EMBL:Z95558) (262 aa) fasta scores: E(): 0, 83.5% id in 261 aa. Shows weak similar [...]
menD protein networkhttps://string-db.org/network/272631.gene:175761292-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resultin [...]
ML2271 protein networkhttps://string-db.org/network/272631.gene:17576130Putative membrane protein; Similar to Mycobacterium tuberculosis putative membrane protein Rv0556 or MTCY25D10.35 TR:O06422 (EMBL:Z95558) (171 aa) fasta scores: E(): 0, 79.2% id in 168 aa. Contai [...]
ML2273 protein networkhttps://string-db.org/network/272631.gene:17576132Putative ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
ML2276 protein networkhttps://string-db.org/network/272631.gene:17576135Putative FAD-linked oxidoreductase; Similar to Mycobacterium tuberculosis hypothetical protein Rv0561c or MTCY25D10.40C TR:O06427 (EMBL:Z95558) (408 aa) fasta scores: E(): 0, 84.5% id in 406 aa. [...]
ML2277 protein networkhttps://string-db.org/network/272631.gene:17576136Similar to Mycobacterium tuberculosis putative heptaprenyl diphosphate synthase Rv0562 or MTCY25D10.41 TR:O06428 (EMBL:Z95558) (335 aa) fasta scores: E(): 0, 76.4% id in 335 aa and to Mycobacteri [...]
htpX protein networkhttps://string-db.org/network/272631.gene:17576137Putative peptidase; Similar to Mycobacterium tuberculosis probable protease htpX or Rv0563 or MTV039.01 or MTCY25D10.42 SW:HTPX_MYCTU (O06429) (286 aa) fasta scores: E(): 0, 88.5% id in 286 aa. S [...]
ML2279 protein networkhttps://string-db.org/network/272631.gene:17576138Similar to Mycobacterium tuberculosis putative membrane protein Rv3273 or MTCY71.13 TR:P96878 (EMBL:Z92771) (764 aa) fasta scores: E(): 0, 59.4% id in 483 aa. Similar to many putative membrane pr [...]
ML2283 protein networkhttps://string-db.org/network/272631.gene:17576143Hypothetical protein; Unknown function.
ML2284 protein networkhttps://string-db.org/network/272631.gene:17576144Hypothetical protein; Unknown function.
ML2288 protein networkhttps://string-db.org/network/272631.gene:17576148Hypothetical protein; Unknown function.
ML2289 protein networkhttps://string-db.org/network/272631.gene:17576149Similar to Mycobacterium tuberculosis hypothetical protein Rv3662c or MTV025.010C TR:O69630 (EMBL:AL022121) (256 aa) fasta scores: E(): 0, 78.0% id in 255 aa and to Streptomyces coelicolor putati [...]
ML2295 protein networkhttps://string-db.org/network/272631.gene:17576155Conserved hypothetical protein; Similar to Mycobacterium tuberculosis putative alkaline serine protease Rv3668c or MTV025.016C TR:O69636 (EMBL:AL022121) (232 aa) fasta scores: E(): 0, 77.1% id in [...]
ML2296 protein networkhttps://string-db.org/network/272631.gene:17576156Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein Rv3669 or MTV025.017 TR:O69637 (EMBL:AL022121) (172 aa) fasta scores: E(): 0, 77.9% id in 181 aa. Similar to [...]
ML2297 protein networkhttps://string-db.org/network/272631.gene:17576157Putative hydrolase; Similar to Mycobacterium tuberculosis putative epoxide hydrolase Rv3670 or MTV025.018 TR:O69638 (EMBL:AL022121) (327 aa) fasta scores: E(): 0, 80.6% id in 324 aa. Similar many [...]
ML2298 protein networkhttps://string-db.org/network/272631.gene:17576158Similar to Mycobacterium tuberculosis putative serine protease Rv3671c or MTV025.019C TR:O69639 (EMBL:AL022121) (397 aa) fasta scores: E(): 0, 80.9% id in 398 aa. Similar to many putative serine [...]
ML2299 protein networkhttps://string-db.org/network/272631.gene:17576159Similar to Mycobacterium tuberculosis hypothetical protein Rv3672c or MTV025.020C TR:O69640 (EMBL:AL022121) (273 aa) fasta scores: E(): 0, 76.4% id in 267 aa. Similar to hypothetical proteins e.g [...]
ML2300 protein networkhttps://string-db.org/network/272631.gene:17576160Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein Rv3673c or MTV025.021C TR:O69641 (EMBL:AL022121) (227 aa) fasta scores: E(): 0, 71.2% id in 215 aa. Shows wea [...]
nth protein networkhttps://string-db.org/network/272631.gene:17576161Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleavi [...]
ML2302 protein networkhttps://string-db.org/network/272631.gene:17576162Similar to Mycobacterium tuberculosis putative transcriptional regulator Rv3676 or MTV025.024 TR:O69644 (EMBL:AL022121) (224 aa) fasta scores: E(): 0, 96.0% id in 224 aa. Similar to many e.g. Hae [...]
ML2303 protein networkhttps://string-db.org/network/272631.gene:17576163Putative hydrolase; Similar to Mycobacterium tuberculosis putative hydrolase Rv3677c or MTV025.025C TR:O69645 (EMBL:AL022121) (264 aa) fasta scores: E(): 0, 83.9% id in 255 aa. Shows similarity t [...]
ML2304 protein networkhttps://string-db.org/network/272631.gene:17576164Conserved hypothetical protein; Similar to Mycobacterium tuberculosis putative transcriptional regulator Rv3678c or MTV025.026C TR:O69646 (EMBL:AL022121) (151 aa) fasta scores: E(): 0, 78.1% id i [...]
ML2305 protein networkhttps://string-db.org/network/272631.gene:17576165Probable anion transporter protein; Similar to Mycobacterium tuberculosis putative ATPase Rv3679 SW:Y0H9_MYCTU (O69647) (340 aa) fasta scores: E(): 0, 84.2% id in 341 aa, and to Streptomyces coel [...]
ML2306 protein networkhttps://string-db.org/network/272631.gene:17576166Probable anion transporter protein; Similar to Mycobacterium tuberculosis putative anion transporting ATPase Rv3680 TR:O69648 (EMBL:AL022121) (386 aa) fasta scores: E(): 0, 88.1% id in 370 aa, an [...]
ML2307 protein networkhttps://string-db.org/network/272631.gene:17576167Hypothetical protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
pon1 protein networkhttps://string-db.org/network/272631.gene:17576168Previously characterised Mycobacterium leprae penicillin-binding protein Pon1 TR:P72351 (EMBL:S82044) (821 aa) fasta scores: E(): 0, 98.6% id in 783 aa. Contains a possible N-terminal signal sequ [...]
ML2309 protein networkhttps://string-db.org/network/272631.gene:17576169Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 34.4 kDa protein Rv3683 TR:O69651 (EMBL:AL022121) (319 aa) fasta scores: E(): 0, 85.8% id in 298 aa, and to Stre [...]
ML2312 protein networkhttps://string-db.org/network/272631.gene:17576173Possible membrane protein; Similar to the C-terminus of Mycobacterium tuberculosis hypothetical protein Rv3695 TR:O69663 (EMBL:AL022121) (310 aa) fasta scores: E(): 0, 71.1% id in 190 aa and Stre [...]
ML2313 protein networkhttps://string-db.org/network/272631.gene:17576174Hypothetical protein; Unknown function.
glpK protein networkhttps://string-db.org/network/272631.gene:17576175Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
ML2321 protein networkhttps://string-db.org/network/272631.gene:17576182Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 36.5 kDa protein Rv3707c TR:O69675 (EMBL:AL022121) (336 aa) fasta scores: E(): 0, 81.6% id in 332 aa, and to Myc [...]
asd protein networkhttps://string-db.org/network/272631.gene:17576183Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the as [...]
ask protein networkhttps://string-db.org/network/272631.gene:17576184Aspartokinase; Similar to Mycobacterium tuberculosis aspartokinase ask or rv3709c or mtv025.057C SW:AK_MYCTU (P97048; O69676; P97181) (421 aa) fasta scores: E(): 0, 92.6% id in 421 aa, and to Myc [...]
leuA protein networkhttps://string-db.org/network/272631.gene:175761852-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isoprop [...]
ML2326 protein networkhttps://string-db.org/network/272631.gene:17576187Possible ligase; Similar to several MurCDEF-family proteins e.g. Mycobacterium tuberculosis UDP-N-acetylmuramate--alanine ligase Rv2152c SW:MURC_MYCTU (O06225) (494 aa) fasta scores: E(): 0.0013, [...]
ML2327 protein networkhttps://string-db.org/network/272631.gene:17576188Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 24.2 kDa protein Rv3713 TR:O69680 (EMBL:AL022121) (231 aa) fasta scores: E(): 0, 86.5% id in 230 aa. Also weakly [...]
recR protein networkhttps://string-db.org/network/272631.gene:17576190DNA repair protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
ML2330 protein networkhttps://string-db.org/network/272631.gene:17576191Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
ML2331 protein networkhttps://string-db.org/network/272631.gene:17576192Possible secreted protein; Similar to Mycobacterium tuberculosis hypothetical 24.8 kDa protein Rv3717 TR:O69684 (EMBL:AL022121) (241 aa) fasta scores: E(): 0, 82.0% id in 244 aa, and to Streptomy [...]
ML2332 protein networkhttps://string-db.org/network/272631.gene:17576193Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 15.7 kDa protein Rv3718c TR:O69685 (EMBL:AL022121) (147 aa) fasta scores: E(): 0, 81.9% id in 144 aa and Strepto [...]
ML2333 protein networkhttps://string-db.org/network/272631.gene:17576194Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 53.0 kDa protein Rv3719 TR:O69686 (EMBL:AL022121) (470 aa) fasta scores: E(): 0, 82.8% id in 458 aa.
ML2334 protein networkhttps://string-db.org/network/272631.gene:17576195Hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 46.9 kDa protein Rv3720 TR:O69687 (EMBL:AL022121) (420 aa) fasta scores: E(): 0, 86.4% id in 420 aa. The C-terminus is sim [...]
dnaZX protein networkhttps://string-db.org/network/272631.gene:17576196DNA polymerase III, subunit [gamma/tau]; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to [...]
ML2336 protein networkhttps://string-db.org/network/272631.gene:17576197Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 44.4 kDa protein Rv3722c TR:O69689 (EMBL:AL022121) (408 aa) fasta scores: E(): 0, 87.6% id in 396 aa, and to Dei [...]
ML2337 protein networkhttps://string-db.org/network/272631.gene:17576199Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein Rv3723 TR:O69690 (EMBL:AL022121) (254 aa) fasta scores: E(): 0, 64.4% id in 253 aa. Contains possible membran [...]
ML2341 protein networkhttps://string-db.org/network/272631.gene:17576203Possible regulatory protein; The N-terminus of the predicted product of this CDS is similar to many adenylate cyclases e.g. Stigmatella aurantiaca adenylate cyclase 2 CyaB SW:CYAB_STIAU (P40138; [...]
ML2346 protein networkhttps://string-db.org/network/272631.gene:17576208Hypothetical protein; Function unknown. Note the G+C content of this CDS (54%).
ML2347 protein networkhttps://string-db.org/network/272631.gene:17576209Putative membrane protein; Function unknown. Note the low G+C content of this CDS (46%). Contains a possible membrane spanning hydrophobic domain.
ML2348 protein networkhttps://string-db.org/network/272631.gene:17576210Similar to many proposed glycosyl transferases including: Mycobacterium tuberculosis hypothetical protein Rv1524 SW:YF24_MYCTU (Q50583) (414 aa) fasta scores: E(): 0, 62.6% id in 420 aa, and to M [...]
ML2349 protein networkhttps://string-db.org/network/272631.gene:17576211Conserved hypothetical protein; Catalyzes diesterification of phthiocerol, phthiodiolone, and phenolphthiocerol with mycocerosic acids, the final step in the phthiocerol, phthiodiolone and phenol [...]
ML2350 protein networkhttps://string-db.org/network/272631.gene:17576212Probable antibiotic resistance membrane protein; Similar to several antibiotic resistant proteins including: Mycobacterium tuberculosis rv2938 TR:P96207 (EMBL:Z83857) (276 aa) fasta scores: E(): [...]
ML2351 protein networkhttps://string-db.org/network/272631.gene:17576213Probable antibiotic resistance membrane protein; Similar to several antibiotic resistant proteins including: Mycobacterium tuberculosis Rv2937 TR:P96206 (EMBL:Z83857) (289 aa) fasta scores: E(): [...]
ML2352 protein networkhttps://string-db.org/network/272631.gene:17576214Probable antibiotic resistance efflux protein; Similar to several antibiotic resistant proteins including: Mycobacterium tuberculosis Rv2936 TR:P96205 (EMBL:Z83857) (331 aa) fasta scores: E(): 0, [...]
ML2353 protein networkhttps://string-db.org/network/272631.gene:17576215Similar to many polyketide synthases e.g. Mycobacterium tuberculosis Rv2935 TR:P96204 (EMBL:Z83857) (1488 aa) fasta scores: E(): 0, 82.0% id in 1493 aa. Contains Pfam match to entry PF00109 ketoa [...]
ML2354 protein networkhttps://string-db.org/network/272631.gene:17576216Similar to many polyketide synthases e.g.Mycobacterium tuberculosis Rv2934 TR:P96203 (EMBL:Z83857) (1827 aa) fasta scores: E(): 0, 80.3% id in 1836 aa, and to Mycobacterium bovis mycocerosic acid [...]
ML2355 protein networkhttps://string-db.org/network/272631.gene:17576217Similar to several polyketide synthases e.g. Mycobacterium tuberculosis Rv2933 TR:P96202 (EMBL:Z83857) (2188 aa) fasta scores: E(): 0, 82.3% id in 2217 aa. Contains Pfam match to entry PF00109 ke [...]
ML2356 protein networkhttps://string-db.org/network/272631.gene:17576218Similar to many polyketide synthases including: Mycobacterium tuberculosis phenolpthiocerol synthesis polyketide synthase Rv2932 SW:PPSB_MYCTU (Q10978; O53234) (1538 aa) fasta scores: E(): 0, 76. [...]
ML2357 protein networkhttps://string-db.org/network/272631.gene:17576219Polyketide synthase; Highly similar to many Prokaryotic and Eukaryotic polyketide synthases including: Mycobacterium tuberculosis phenolpthiocerol synthase rv2931 SW:PPSA_MYCTU (Q10977) (1876 aa) [...]
fadD26 protein networkhttps://string-db.org/network/272631.gene:17576220Probable acyl-CoA synthase; Similar to Mycobacterium tuberculosis acyl-CoA synthase Rv1185c TR:O50441 (EMBL:AL010186) (578 aa) fasta scores: E(): 0, 56.9% id in 580 aa, and to Myxococcus xanthus [...]
ML2359 protein networkhttps://string-db.org/network/272631.gene:17576221Thioesterase; Involved in the synthesis of both phthiocerol dimycocerosates (PDIMs) and phenolic glycolipids (PGLs), which are structurally related lipids non-covalently bound to the outer cell w [...]
ML2366 protein networkhttps://string-db.org/network/272631.gene:17576228Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 10.6 kDa protein rv3760 or mtv025.108 TR:O69726 (EMBL:AL022121) (100 aa) fasta scores: E(): 1.9e-19, 67.7% id in 99 a [...]
ML2377 protein networkhttps://string-db.org/network/272631.gene:17576239Similar to Mycobacterium tuberculosis putative membrane protein Rv0451c SW:MMS4_MYCTU (O53736) (140 aa) fasta scores: E(): 0, 75.0% id in 140 aa, and to Mycobacterium avium TmtpA TR:Q9XCF4 (EMBL: [...]
ML2378 protein networkhttps://string-db.org/network/272631.gene:17576240Similar to many membrane proteins including: Mycobacterium tuberculosis putative membrane protein Mmpl4 or Rv0450c SW:MML4_MYCTU (O53735) (967 aa) fasta scores: E(): 0, 78.4% id in 962 aa, and to [...]
ML2379 protein networkhttps://string-db.org/network/272631.gene:17576241Hypothetical protein; Unknown function.
ML2380 protein networkhttps://string-db.org/network/272631.gene:17576242Possible secreted protein; Similar to Mycobacterium tuberculosis hypothetical protein Rv0455c TR:O53740 (EMBL:AL021932) (148 aa) fasta scores: E(): 0, 66.4% id in 152 aa. Contains a possible N-te [...]
lpd protein networkhttps://string-db.org/network/272631.gene:17576249Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes. Catalyzes the reoxidation of dihydrolipoyl groups which are covalently attach [...]
ML2388 protein networkhttps://string-db.org/network/272631.gene:17576250Possible membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein Rv0463 TR:O53748 (EMBL:AL021933) (97 aa) fasta scores: E(): 1.1e-18, 57.9% id in 95 aa. Contains possible mem [...]
ML2390 protein networkhttps://string-db.org/network/272631.gene:17576252Possible secreted protein; Similar to Mycobacterium tuberculosis hypothetical protein Rv1083 TR:O53431 (EMBL:AL021897) (88 aa) fasta scores: E(): 4.9e-15, 57.4% id in 101 aa. Contains a possible [...]
ML2391 protein networkhttps://string-db.org/network/272631.gene:17576253Conserved hypothetical protein; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, [...]
ML2392 protein networkhttps://string-db.org/network/272631.gene:17576254Conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein Rv1081c TR:O53429 (EMBL:AL021897) (144 aa) fasta scores: E(): 0, 69.0% id in 142 aa. Contains a possible mem [...]
greA protein networkhttps://string-db.org/network/272631.gene:17576255Transcription elongation factor G; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping [...]
metB protein networkhttps://string-db.org/network/272631.gene:17576256Cystathionine [gamma]-synthase; Catalyzes the formation of L-cystathionine from O-succinyl-L- homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyze [...]
Ag36 protein networkhttps://string-db.org/network/272631.gene:17576257Previously characterised Mycobacterium leprae proline-rich antigen Ag36 SW:PRA_MYCLE (P41484) (249 aa) fasta scores: E(): 0, 99.2% id in 249 aa. Note the N-terminus of this protein is extremely r [...]
cysM2 protein networkhttps://string-db.org/network/272631.gene:17576258Similar to Prokaryotic and Eukaryotic cystathionine beta-synthases including: Mycobacterium tuberculosis Rv1077 TR:O53425 (EMBL:AL021897) (464 aa) fasta scores: E(): 0, 90.1% id in 464 aa and Hom [...]
ML2400 protein networkhttps://string-db.org/network/272631.gene:17576262Probable transmembrane protein; Similar to Mycobacterium tuberculosis putative transmembrane protein rv1072 or mtv017.25 TR:O53420 (EMBL:AL021897) (278 aa) fasta scores: E(): 0, 77.5% id in 285 a [...]
ML2401 protein networkhttps://string-db.org/network/272631.gene:17576263Similar to several putative Prokaryotic and Eukaryotic enoyl-CoA hydratases including: Mycobacterium tuberculosis Rv1071c TR:O53419 (EMBL:AL021897) (345 aa) fasta scores: E(): 0, 77.7% id in 345 [...]
ML2402 protein networkhttps://string-db.org/network/272631.gene:17576264Putative enoyl-CoA hydratase/isomerase; Could possibly oxidize fatty acids using specific components.
ML2406 protein networkhttps://string-db.org/network/272631.gene:17576268Probable 4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
ML2407 protein networkhttps://string-db.org/network/272631.gene:17576269Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 11.4 kDa protein rv0531 or mtcy25d10.10 TR:O06397 (EMBL:Z95558) (105 aa) fasta scores: E(): 2.4e-24, 73.1% id in 93 a [...]
ML2409 protein networkhttps://string-db.org/network/272631.gene:17576271Similar to many cytochrome C biogenesis proteins including Mycobacterium tuberculosis Rv0529 TR:O06395 (EMBL:Z95558) (324 aa) fasta scores: E(): 0, 83.2% id in 327 aa, and to Guillardia theta Ccs [...]
ML2410 protein networkhttps://string-db.org/network/272631.gene:17576272Conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein Rv0528 TR:O06394 (EMBL:Z95558) (529 aa) fasta scores: E(): 0, 80.9% id in 530 aa. Contains multiple possible [...]
ML2411 protein networkhttps://string-db.org/network/272631.gene:17576273Possible cytochrome C-type biogenesis protein; Similar to Mycobacterium tuberculosis hypothetical protein Rv0527 TR:O06393 (EMBL:Z95558) (259 aa) fasta scores: E(): 0, 79.0% id in 262 aa, and to [...]
ML2412 protein networkhttps://string-db.org/network/272631.gene:17576274Similar to Mycobacterium tuberculosis hypothetical protein Rv0526 TR:O06392 (EMBL:Z95558) (216 aa) fasta scores: E(): 0, 78.5% id in 214 aa.
ML2413 protein networkhttps://string-db.org/network/272631.gene:17576275Possible phosphoglycerate mutase; Similar to Mycobacterium tuberculosis protein Rv0525 TR:O06391 (EMBL:Z95558) (202 aa) fasta scores: E(): 0, 82.5% id in 200 aa, and to Escherichia coli probable [...]
hemL protein networkhttps://string-db.org/network/272631.gene:17576276Similar to Mycobacterium tuberculosis glutamate-1-semialdehyde 2,1-aminomutase HemL Rv0524 SW:GSA_MYCTU (O06390) (462 aa) fasta scores: E(): 0, 82.4% id in 460 aa, and to Escherichia coli glutama [...]
hemB protein networkhttps://string-db.org/network/272631.gene:17576281[delta]-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes [...]
hemD protein networkhttps://string-db.org/network/272631.gene:17576282Possible uroporphyrin-III C-methyltransferase; Similar to Mycobacterium tuberculosis Rv0511 TR:P95077 (EMBL:Z83865) (565 aa) fasta scores: E(): 0, 85.7% id in 565 aa and to Clostridium josui porp [...]
hemC protein networkhttps://string-db.org/network/272631.gene:17576283Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
hemA protein networkhttps://string-db.org/network/272631.gene:17576284glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
ML2424 protein networkhttps://string-db.org/network/272631.gene:17576286Conserved hypothetical protein; Similar to several including: Mycobacterium tuberculosis phosphoserine phosphatase SerB Rv0505c SW:Y505_MYCTU (Q11169) (373 aa) fasta scores: E(): 0, 83.0% id in 3 [...]
ML2425 protein networkhttps://string-db.org/network/272631.gene:17576287Similar to Mycobacterium tuberculosis hypothetical protein Rv0504c SW:Y504_MYCTU (Q11168) (166 aa) fasta scores: E(): 0, 83.1% id in 166 aa; Similar to ML1908 and ML1910; Belongs to the UPF0336 f [...]
cmaA2 protein networkhttps://string-db.org/network/272631.gene:17576288Cyclopropane mycolic acid synthase; Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal [...]
ML2427 protein networkhttps://string-db.org/network/272631.gene:17576289Similar to Mycobacterium tuberculosis hypothetical protein Rv0502 SW:Y502_MYCTU (Q11167) (358 aa) fasta scores: E(): 0, 85.2% id in 359 aa. Contains a Pfam match to PF01553 Acyltransferase. Conta [...]
ML2428 protein networkhttps://string-db.org/network/272631.gene:17576290Possible glucose epimerase/dehydratase; Similar to Mycobacterium tuberculosis UDP-glucose 4-epimerase Rv0501 SW:Y501_MYCTU (Q11166) (376 aa) fasta scores: E(): 0, 84.0% id in 368 aa, and to Strep [...]
ML2428A protein networkhttps://string-db.org/network/272631.gene:17576291Uncharacterized protein ML2428.1; ML2428A. Orthologue of M. tuberculosis Rv0500B. Conserved hypothetical protein, strongly basic. Also similar to Streptomyces coelicolor SCE68.25c, hypothetical p [...]
ML2429 protein networkhttps://string-db.org/network/272631.gene:17576292Possible DNA-binding protein; Weakly similar to several including: Streptomyces coelicolor hypothetical protein TR:Q9WX06 (EMBL:AL079345) (70 aa) fasta scores: E(): 3.4e-14, 68.3% id in 63 aa. Co [...]
proC protein networkhttps://string-db.org/network/272631.gene:17576293Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
ML2432 protein networkhttps://string-db.org/network/272631.gene:17576295Similar to Mycobacterium tuberculosis hypothetical protein Rv0498 SW:Y498_MYCTU (Q11163) (280 aa) fasta scores: E(): 0, 89.3% id in 280 aa, and to Streptomyces coelicolor hypothetical protein TR: [...]
ML2433 protein networkhttps://string-db.org/network/272631.gene:17576296Conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical 33.1 kda protein Rv0497 SW:Y497_MYCTU (Q11162) (310 aa) fasta scores: E(): 4.6e-21, 54.2% id in 356 aa. Contains mul [...]
ML2434 protein networkhttps://string-db.org/network/272631.gene:17576297Conserved hypothetical protein; Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain.
ML2435 protein networkhttps://string-db.org/network/272631.gene:17576298Similar to Mycobacterium tuberculosis hypothetical protein Rv0495c SW:Y495_MYCTU (Q11160) (296 aa) fasta scores: E(): 0, 82.7% id in 271 aa, and to Streptomyces coelicolor hypothetical protein TR [...]
ML2439 protein networkhttps://string-db.org/network/272631.gene:17576302Probable two-component system response regulator; Probably forms part of a two-component regulatory system RegX3/SenX3.
ML2440 protein networkhttps://string-db.org/network/272631.gene:17576303Probable two-component system sensor histidine kinase; Probably forms part of a two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 (Probable).
gpm protein networkhttps://string-db.org/network/272631.gene:17576304Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
ML2442 protein networkhttps://string-db.org/network/272631.gene:17576305Similar to Mycobacterium tuberculosis hypothetical protein Rv0487 SW:Y487_MYCTU (Q11153) (183 aa) fasta scores: E(): 0, 69.2% id in 172 aa; To M.tuberculosis Rv0487.
ML2443 protein networkhttps://string-db.org/network/272631.gene:17576306Possible glycosyl transferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate i [...]
ML2446 protein networkhttps://string-db.org/network/272631.gene:17576309Possible lipoprotein; Similar to Mycobacterium tuberculosis hypothetical protein Rv0483 SW:Y483_MYCTU (Q11149) fasta scores: E(): 0, 79.3% id in 439 aa, and to Streptomyces coelicolor putative li [...]
murB protein networkhttps://string-db.org/network/272631.gene:17576310UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
ML2449 protein networkhttps://string-db.org/network/272631.gene:17576312Putative hydrolase; Similar to several including: Mycobacterium tuberculosis hypothetical protein Rv0480c SW:Y480_MYCTU (Q11146) fasta scores: E(): 0, 81.9% id in 270 aa, and to Streptomyces coel [...]
ML2450 protein networkhttps://string-db.org/network/272631.gene:17576313Possible secreted protein; Similar to the C-terminal region of Mycobacterium tuberculosis hypothetical protein Rv0479c SW:Y479_MYCTU (Q11145) fasta scores: E(): 0, 70.0% id in 243 aa. Contains a [...]
deoC protein networkhttps://string-db.org/network/272631.gene:17576314Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB ald [...]
ML2452 protein networkhttps://string-db.org/network/272631.gene:17576315Hypothetical protein; Weakly similar in parts to Mycobacterium tuberculosis hypothetical protein Rv0477 SW:Y477_MYCTU (Q11144) fasta scores: E(): 1.8e-23, 57.3% id in 110 aa; To M.tuberculosis Rv [...]
ML2453 protein networkhttps://string-db.org/network/272631.gene:17576316Conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical rv0476 precursor rv0476 or mtcy20g9.02 SW:Y476_MYCTU (Q11143) fasta scores: E(): 1.6e-24, 83.9% id in 87 aa. Contain [...]
ML2454 protein networkhttps://string-db.org/network/272631.gene:17576317Possible hemagglutinin; Might mediate adherence to host cells by binding sulfated glycoconjugates.
ML2457 protein networkhttps://string-db.org/network/272631.gene:17576320Possible TetR-family transcriptional regulator; Similar several putative trancriptional regulators e.g. Mycobacterium tuberculosis putative regulatory protein Rv0472c TR:O53757 (EMBL:AL021933) fa [...]
umaA2 protein networkhttps://string-db.org/network/272631.gene:17576322Mycolic acid synthase; Highly similar to many mycobacterial mycolic acid synthases including: Mycobacterium tuberculosis cyclopropane-fatty-acyl-phospholipid synthase 1 Rv3392c SW:CFA1_MYCTU (Q11 [...]
fadB2 protein networkhttps://string-db.org/network/272631.gene:175763243-hydroxyacyl-CoA dehydrogenase; Similar to Mycobacterium tuberculosis putative 3-hydroxyacyl-CoA dehydrogenase Rv0468 TR:O53753 (EMBL:AL021933) fasta scores: E(): 0, 89.5% id in 287 aa, and to C [...]
ML2463 protein networkhttps://string-db.org/network/272631.gene:17576326Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 30.2 kda protein Rv0466 TR:O53751 (EMBL:AL021933) fasta scores: E(): 0, 87.1% id in 264 aa.
ML2465 protein networkhttps://string-db.org/network/272631.gene:17576328Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 21.3 kda protein Rv0464c TR:O53749 (EMBL:AL021933) fasta scores: E(): 0, 67.4% id in 187 aa.
ML2467 protein networkhttps://string-db.org/network/272631.gene:17576330Possible undecaprenyl pyrophosphate synthetase; Generates Z-farnesyl diphosphate (Z-FPP) from isopentenyl pyrophosphate (IPP). Z-FPP is the precursor of decaprenyl diphosphate, which has a centra [...]
ML2472 protein networkhttps://string-db.org/network/272631.gene:17576335Possible prephenate dehydrogenase; Similar to Mycobacterium tuberculosis putative oxidoreductase Rv3754 TR:O69721 (EMBL:AL022121) fasta scores: E(): 0, 80.0% id in 300 aa and to Bacillus subtilis [...]
ML2473 protein networkhttps://string-db.org/network/272631.gene:17576336Similar to Mycobacterium tuberculosis hypothetical protein Rv3753c TR:O69720 (EMBL:AL022121) fasta scores: E(): 0, 88.3% id in 163 aa.
ML2474 protein networkhttps://string-db.org/network/272631.gene:17576337Possible cytidine/deoxycytidylate deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase famil [...]
ML2476 protein networkhttps://string-db.org/network/272631.gene:17576340Similar in parts to several proteins of undefined function e.g. Streptomyces coelicolor hypothetical protein TR:Q9X8J2 (EMBL:AL049841) fasta scores: E(): 5.6e-10, 53.1% id in 64 aa.
ML2478 protein networkhttps://string-db.org/network/272631.gene:17576342Hypothetical protein; Doubtful CDS.
ML2485 protein networkhttps://string-db.org/network/272631.gene:17576349Possible RNA methyltransferase; Similar to Mycobacterium tuberculosis hypothetical protein Rv0380c TR:O53715 (EMBL:AL021931) fasta scores: E(): 0, 89.0% id in 182 aa, and to Escherichia coli SpoU [...]
ML2487 protein networkhttps://string-db.org/network/272631.gene:17576351Probable purine/pyrimidine phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine mon [...]
ML2489 protein networkhttps://string-db.org/network/272631.gene:17576353Possible secreted protein; Similar to Mycobacterium tuberculosis hypothetical 31.8 kda protein rv0383c or mtv036.18c TR:O53718 (EMBL:AL021931) fasta scores: E(): 0, 82.2% id in 286 aa. Contains a [...]
clpB protein networkhttps://string-db.org/network/272631.gene:17576354Heat shock protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK [...]
ML2491 protein networkhttps://string-db.org/network/272631.gene:17576355Hypothetical protein; Similar to the C-terminus of Mycobacterium tuberculosis hypothetical protein RV1754C TR:O06790 (EMBL:Z95890) (563 aa) fasta scores: E(): 0, 71.1% id in 336 aa, and to Mycoba [...]
hspR protein networkhttps://string-db.org/network/272631.gene:17576357Heat shock regulator; Similar to Mycobacterium tuberculosis HspR OR RV0353 TR:O06302 (EMBL:Z95324) fasta scores: E(): 0, 80.0% id in 125 aa, and to Streptomyces albus TR:P96458 (EMBL:U43299) fast [...]
dnaJ protein networkhttps://string-db.org/network/272631.gene:17576358Hsp70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomo [...]
grpE protein networkhttps://string-db.org/network/272631.gene:17576359Hsp70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucle [...]
dnaK protein networkhttps://string-db.org/network/272631.gene:1757636070 kD heat shock protein (molecular chaperone); Acts as a chaperone; Belongs to the heat shock protein 70 family.
ML2497 protein networkhttps://string-db.org/network/272631.gene:17576361Hypothetical protein; Unknown function.
ML2498 protein networkhttps://string-db.org/network/272631.gene:17576362Possible enoyl-CoA hydratase; Similar to several proteins belonging to the enoyl-CoA hydratase/isomerase family e.g. Arabidopsis thaliana carnitine racemase homolog TR:O23300 (EMBL:Z97336) fasta [...]
ML2501 protein networkhttps://string-db.org/network/272631.gene:17576365Probable iron-sulphur-binding reductase; Similar to Mycobacterium tuberculosis hypothetical protein RV0338C TR:O33268 (EMBL:Z97991) fasta scores: E(): 0, 78.1% id in 894 aa, and to Streptomyces c [...]
ML2502 protein networkhttps://string-db.org/network/272631.gene:17576366Similar to Mycobacterium tuberculosis probable aspartate aminotransferase RV0337C SW:AAT_MYCTU (O33267) fasta scores: E(): 0, 91.4% id in 429 aa and to Bacillus stearothermophilus aspartate amino [...]
rfbA protein networkhttps://string-db.org/network/272631.gene:17576367Glucose-1-phosphate thymidyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidyl [...]
ML2507 protein networkhttps://string-db.org/network/272631.gene:17576371Probable deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermed [...]
ML2522 protein networkhttps://string-db.org/network/272631.gene:17576387Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 22.5 kda protein RV0309 TR:O07236 (EMBL:Z96800) fasta scores: E(): 0, 78.0% id in 218 aa, and to Streptomyces coelico [...]
ML2527 protein networkhttps://string-db.org/network/272631.gene:17576392Conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein RV0292 TR:O53696 (EMBL:AL021930) fasta scores: E(): 0, 61.6% id in 333 aa. Contains possible membrane spanni [...]
ML2528 protein networkhttps://string-db.org/network/272631.gene:17576393Similar to many proposed proteases e.g. Mycobacterium tuberculosis putative protease RV0291 TR:O53695 (EMBL:AL021930) fasta scores: E(): 0, 69.9% id in 468 aa. Contains 2 Pfam matches to entry PF [...]
ML2529 protein networkhttps://string-db.org/network/272631.gene:17576394Conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein RV0290 TR:O86362 (EMBL:AL021930) fasta scores: E(): 0, 76.4% id in 471 aa, and to Streptomyces coelicolor pu [...]
ML2530 protein networkhttps://string-db.org/network/272631.gene:17576395Possible DNA-binding protein; Similar to Mycobacterium tuberculosis hypothetical protein RV0289 TR:O53694 (EMBL:AL021930) fasta scores: E(): 0, 75.9% id in 295 aa. Contains a probable helix-turn- [...]
ML2531 protein networkhttps://string-db.org/network/272631.gene:17576396Possible cell surface protein; Similar to Mycobacterium tuberculosis 10 kda antigenic protein RV0288 SW:CFP7_MYCTU (O53693) fasta scores: E(): 6.1e-29, 70.5% id in 95 aa.
ML2532 protein networkhttps://string-db.org/network/272631.gene:17576397PE-family protein; Similar to Mycobacterium tuberculosis PE-family protein RV3020C TR:O53267 (EMBL:AL021287) fasta scores: E(): 5.5e-26, 73.7% id in 95 aa; Belongs to the WXG100 family.
ML2534 protein networkhttps://string-db.org/network/272631.gene:17576399PE-family protein; Similar to Mycobacterium tuberculosis PE-family protein RV0285 OR MTV035.13 TR:O53690 (EMBL:AL021930) fasta scores: E(): 2.1e-23, 73.0% id in 100 aa.
ML2535 protein networkhttps://string-db.org/network/272631.gene:17576400Similar to Mycobacterium tuberculosis hypothetical protein RV0284 TR:O53689 (EMBL:AL021930) fasta scores: E(): 0, 84.2% id in 1318 aa and to Streptomyces coelicolor ATP/GTP binding protein SC3C3. [...]
ML2536 protein networkhttps://string-db.org/network/272631.gene:17576401Conserved membrane protein; Similar to several Mycobacterium tuberculosis hypothetical proteins e.g. RV0283 TR:O53688 (EMBL:AL021930) fasta scores: E(): 0, 70.8% id in 552 aa. Contains a possible [...]
ML2537 protein networkhttps://string-db.org/network/272631.gene:17576402Conserved hypothetical protein; Part of an ESX-3 / type VII specialized secretion system (T7SS), which exports several proteins. EccA3 exhibits ATPase activity and may provide energy for the expo [...]
fadD2 protein networkhttps://string-db.org/network/272631.gene:17576411acyl-CoA synthase; Similar to Rhizobium trifolii malonyl CoA synthetase MATB TR:Q9ZIP5 (EMBL:AF117694) fasta scores: E(): 2.4e-31, 31.2% id in 507 aa and Mycobacterium tuberculosis hypothetical 5 [...]
ML2549 protein networkhttps://string-db.org/network/272631.gene:17576414Conserved hypothetical protein; Similar to several proteins of undefined function including: Mycobacterium tuberculosis hypothetical protein RV0264C TR:P95221 (EMBL:Z86089) fasta scores: E(): 0, [...]
ML2550 protein networkhttps://string-db.org/network/272631.gene:17576415Conserved hypothetical protein; Similar to many proteins of undefined function including: Mycobacterium tuberculosis hypothetical 32.2 kDa protein RV0263C TR:P95220 (EMBL:Z86089) fasta scores: E( [...]
aac protein networkhttps://string-db.org/network/272631.gene:17576416Highly similar to several mycobacterial aminoglycoside-resistance determinants e.g. Mycobacterium tuberculosis aminoglycoside 2'-n-acetyltransferase Aac OR RV0262C SW:AAC2_MYCTU (P95219; P72033) [...]
ML2557 protein networkhttps://string-db.org/network/272631.gene:17576422Similar to Mycobacterium tuberculosis hypothetical protein RV0250c TR:O53672 (EMBL:AL021929) fasta scores: E(): 2e-26, 72.6% id in 95 aa.
ML2561 protein networkhttps://string-db.org/network/272631.gene:17576426Probable oxidoreductase; Similar to many including: Mycobacterium tuberculosis hypothetical 17.0 kda protein RV0245 OR MTV034.11 TR:O53667 (EMBL:AL021929) fasta scores: E(): 0, 82.0% id in 161 aa [...]
fadE5 protein networkhttps://string-db.org/network/272631.gene:17576428acyl-CoA dehydrogenase; Similar to Mycobacterium tuberculosis putative acyl-CoA dehydrogenase RV0244C TR:O53666 (EMBL:AL021929) fasta scores: E(): 0, 89.4% id in 611 aa. Contains 2 Pfam matches t [...]
fadA2 protein networkhttps://string-db.org/network/272631.gene:17576429acetyl-CoA C-acetyltransferase; Similar to many Prokaryotic and Eukaryotic thiolases including: Escherichia coli probable 3-ketoacyl-coa thiolase YFCY SW:YFCY_ECOLI (P76503) fasta scores: E(): 0, [...]
fabG4 protein networkhttps://string-db.org/network/272631.gene:17576430Possible oxidoreductase; The C-terminal portion of the predicted product of this CDS is highly similar to many 3-oxoacyl-[acyl-carrier protein] reductases e.g. Vibrio harveyi FabG SW:FABG_VIBHA ( [...]
ML2566 protein networkhttps://string-db.org/network/272631.gene:17576431Similar to Mycobacterium tuberculosis hypothetical protein RV0241C TR:O53664 (EMBL:AL021929) fasta scores: E(): 0, 81.8% id in 280 aa, and to Streptomyces coelicolor putative dehydratase TR:CAB77 [...]
ML2567 protein networkhttps://string-db.org/network/272631.gene:17576432Hypothetical protein; Function unknown.
ML2568 protein networkhttps://string-db.org/network/272631.gene:17576433Similar to several putative transcriptional regulators e.g. Mycobacterium tuberculosis RV0238 TR:O53661 (EMBL:AL021929) fasta scores: E(): 0, 80.9% id in 199 aa, and to Streptomyces coelicolor TR [...]
ML2569 protein networkhttps://string-db.org/network/272631.gene:17576434Putative secreted glycosyl hydrolase; Similar to Mycobacterium tuberculosis putative lipoprotein RV0237 TR:O53660 (EMBL:AL021929) fasta scores: E(): 0, 73.2% id in 392 aa. Also similar in regions [...]
ML2569A protein networkhttps://string-db.org/network/272631.gene:17576435Putative secreted protein; Orthologue of Mycobacterium tuberculosis, Rv0236A, small secreted protein with typical N-terminal signal peptide. See J. Bacteriol. 177(1):59-65(1995).
ML2570 protein networkhttps://string-db.org/network/272631.gene:17576436Possible integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein RV0236C TR:P96419 (EMBL:Z92669) fasta scores: E(): 0, 78.7% id in 1397 aa. Contains a possible N-ter [...]
gabD protein networkhttps://string-db.org/network/272631.gene:17576439Succinate-semialdehyde dehydrogenase; Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate. It is believed to be the main source of succinate semialdehyde dehydrogenas [...]
ML2580 protein networkhttps://string-db.org/network/272631.gene:17576446Possible acyltransferase; Similar to Mycobacterium tuberculosis hypothetical protein RV0228 TR:P96410 (EMBL:Z92669) fasta scores: E(): 0, 79.5% id in 381 aa, and to Streptomyces mycarofaciens acy [...]
ML2581 protein networkhttps://string-db.org/network/272631.gene:17576447Putative integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein RV0227C TR:P96409 (EMBL:Z92669) fasta scores: E(): 0, 76.6% id in 423 aa. Contains a possible N-term [...]
ML2582 protein networkhttps://string-db.org/network/272631.gene:17576448Conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical 59.1 kda protein RV0226C OR MTCY08D5.21C TR:P96408 (EMBL:Z92669) fasta scores: E(): 0, 70.1% id in 581 aa. Contains [...]
ML2583 protein networkhttps://string-db.org/network/272631.gene:17576449Putative glycosyl transferase; Similar to Mycobacterium tuberculosis hypothetical protein RV0225 TR:P96407 (EMBL:Z92669) fasta scores: E(): 0, 84.9% id in 383 aa and to Methanobacterium thermoaut [...]
ML2584 protein networkhttps://string-db.org/network/272631.gene:17576450Similar to Mycobacterium tuberculosis hypothetical protein RV0224C TR:P96406 (EMBL:Z92669) fasta scores: E(): 0, 82.9% id in 252 aa. Also weakly to several putative methyltransferases e.g. Synech [...]
yrbE1A protein networkhttps://string-db.org/network/272631.gene:17576453Conserved membrane protein; Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. RV0167 TR:O07412 (EMBL:Z9705 [...]
yrbE1B protein networkhttps://string-db.org/network/272631.gene:17576454Conserved membrane protein; Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. RV0168 TR:O07413 (EMBL:Z9705 [...]
mce1A protein networkhttps://string-db.org/network/272631.gene:17576455Putative cell invasion protein; Highly similar to Mycobacterium tuberculosis Mce proteins associated with entry and survival inside macrophage e.g. RV0169 ORMTCI28.08 TR:P72013 (EMBL:Z97050) fast [...]
mce1B protein networkhttps://string-db.org/network/272631.gene:17576456Putative secreted protein; Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. RV0170 TR:O07414 (EMBL:Z97050 [...]
mce1C protein networkhttps://string-db.org/network/272631.gene:17576457Putative secreted protein; Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g.RV0171 TR:O07415 (EMBL:Z97050) [...]
mce1D protein networkhttps://string-db.org/network/272631.gene:17576458Putative secreted protein; Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. RV0172 TR:O07416 (EMBL:Z97050 [...]
lprK protein networkhttps://string-db.org/network/272631.gene:17576459Putative lipoprotein; Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. RV0173 TR:O07417 (EMBL:Z97050) fas [...]
mce1F protein networkhttps://string-db.org/network/272631.gene:17576460Putative secreted protein; Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. RV0174 TR:O07418 (EMBL:Z97050 [...]
ML2595 protein networkhttps://string-db.org/network/272631.gene:17576461Possible membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein RV0175 TR:O07419 (EMBL:Z97050) fasta scores: E(): 0, 70.5% id in 166 aa. Orthologue of M. tuberculosis Rv0175 [...]
ML2596 protein networkhttps://string-db.org/network/272631.gene:17576462Conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein RV0176 TR:O07420 (EMBL:Z97050) fasta scores: E(): 0, 54.9% id in 319 aa. Contains multiple possible membrane [...]
ML2597 protein networkhttps://string-db.org/network/272631.gene:17576463Conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein RV0177 TR:O07421 (EMBL:Z97050) fasta scores: E(): 0, 60.9% id in 184 aa. Contains a possible membrane spanni [...]
ML2598 protein networkhttps://string-db.org/network/272631.gene:17576464Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 25.9 kda protein RV0178 TR:O07422 (EMBL:Z97050) fasta scores: E(): 0, 65.6% id in 244 aa. Contains a possible N-termi [...]
ML2600 protein networkhttps://string-db.org/network/272631.gene:17576466Probable conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical 47.6 kda protein RV0180C TR:O07424 (EMBL:Z97050) fasta scores: E(): 0, 76.7% id in 447 aa. Contains multipl [...]
ML2603 protein networkhttps://string-db.org/network/272631.gene:17576469Hypothetical protein; Similar to Mycobacterium tuberculosis possible oxidoreductase RV0183 TR:O07427 (EMBL:Z97050) fasta scores: E(): 0, 74.9% id in 279 aa, and to several putative lipases e.g. D [...]
ML2604 protein networkhttps://string-db.org/network/272631.gene:17576470Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 26.8 kda protein RV0184 TR:O07428 (EMBL:Z97050) fasta scores: E(): 0, 81.9% id in 249 aa.
ML2605 protein networkhttps://string-db.org/network/272631.gene:17576471Similar to Mycobacterium tuberculosis hypothetical protein RV0185 TR:O07429 (EMBL:Z97050) fasta scores: E(): 0, 76.4% id in 165 aa.
ilvD protein networkhttps://string-db.org/network/272631.gene:17576474Dihydroxy-acid dehydratase; Similar to many Prokaryotic and Eukaryotic dihydroxy-acid dehydratases involved in valine and isoleucine biosynthesis e.g. Mycobacterium tuberculosis RV0189C SW:ILVD_M [...]
ML2609 protein networkhttps://string-db.org/network/272631.gene:17576475Conserved hypothetical protein; Similar in parts to several proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical protein RV0190 TR:O07434 (EMBL:Z97050) fasta scores: E(): 6 [...]
ML2613 protein networkhttps://string-db.org/network/272631.gene:17576479Similar to Mycobacterium tuberculosis zinc metalloprotease RV0198C TR:O53649 (EMBL:AL021928) fasta scores: E(): 0, 80.8% id in 667 aa. Also similar to many Eukaryotic metalloproteases denoted end [...]
ML2614 protein networkhttps://string-db.org/network/272631.gene:17576480Conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein RV0199 TR:O53650 (EMBL:AL021928) fasta scores: E(): 0, 67.6% id in 219 aa. Contains possible membrane spanni [...]
ML2615 protein networkhttps://string-db.org/network/272631.gene:17576481Probable membrane protein; Similar to several Mycobacterium tuberculosis hypothetical proteins e.g. RV0200 TR:O53651 (EMBL:AL021928) fasta scores: E(): 0, 74.7% id in 229 aa. Contains a possible [...]
ML2616 protein networkhttps://string-db.org/network/272631.gene:17576482Similar to Mycobacterium tuberculosis hypothetical protein RV0201C TR:O53652 (EMBL:AL021928) fasta scores: E(): 0, 63.9% id in 158 aa. Contains PS00402 Binding-protein-dependent transport systems [...]
ML2617 protein networkhttps://string-db.org/network/272631.gene:17576483Similar to Mycobacterium tuberculosis putative membrane protein Mmpl11 RV0202C SW:MMLB_MYCTU (O53653) fasta scores: E(): 0, 72.8% id in 1017 aa, and to Streptomyces coelicolor putative integral m [...]
ML2618 protein networkhttps://string-db.org/network/272631.gene:17576484Probable integral membrane protein; Similar to several proteins of undefined function including: Mycobacterium tuberculosis RV0204C TR:O53655 (EMBL:AL021928) fasta scores: E(): 0, 82.6% id in 374 [...]
ML2620 protein networkhttps://string-db.org/network/272631.gene:17576486Conserved integral membrane protein; Transports trehalose monomycolate (TMM) across the inner membrane; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
ML2621 protein networkhttps://string-db.org/network/272631.gene:17576487Hypothetical protein; Some similarity in regions to Mycobacterium tuberculosis hypothetical protein RV0207C TR:P96389 (EMBL:Z92669) fasta scores: E(): 0, 60.8% id in 199 aa, and to Schizosaccharo [...]
ML2622 protein networkhttps://string-db.org/network/272631.gene:17576488Conserved hypothetical protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
pckA protein networkhttps://string-db.org/network/272631.gene:17576490Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate [...]
ML2627 protein networkhttps://string-db.org/network/272631.gene:17576493Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 35.8 kda protein RV0216 OR MTCY08D5.11 TR:P96398 (EMBL:Z92669) fasta scores: E(): 0, 74.0% id in 338 aa.
ML2629 protein networkhttps://string-db.org/network/272631.gene:17576495Weakly similar to a number of proteins of undefined function e.g. Mycobacterium tuberculosis RV0854 TR:O53866 (EMBL:AL022004) fasta scores: E(): 7.1e-07, 24.6% id in 134 aa; Similar to ML0124.
ML2630 protein networkhttps://string-db.org/network/272631.gene:17576496Hypothetical protein; Highly similar in parts to another Mycobacterium leprae hypothetical protein TR:O32870 (EMBL:Z70722) fasta scores: E(): 2.7e-28, 96.6% id in 88 aa. Note this is a possible p [...]
ML2631 protein networkhttps://string-db.org/network/272631.gene:17576497Possible oxidoreductase; Similar to Mycobacterium tuberculosis hypothetical protein RV0161 TR:O07406 (EMBL:Z97050) fasta scores: E(): 0, 78.8% id in 449 aa, and to Escherichia coli glycolate oxid [...]
pntB protein networkhttps://string-db.org/network/272631.gene:17576500Pyridine transhydrogenase subunit [beta]; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to [...]
pntAB protein networkhttps://string-db.org/network/272631.gene:17576501Pyridine transhydrogenase subunit [alpha]2; Similar to Mycobacterium tuberculosis PntAB OR RV0156 TR:P96833 (EMBL:Z92770) fasta scores: E(): 3.5e-30, 83.0% id in 100 aa, and to Rhodospirillum rub [...]
pntAA protein networkhttps://string-db.org/network/272631.gene:17576502Pyridine transhydrogenase subunit [alpha]1; Similar to Mycobacterium tuberculosis PntAA OR RV0155 TR:P96832 (EMBL:Z92770) fasta scores: E(): 0, 87.9% id in 365 aa, Haemophilus influenzae NAD PntA [...]
ML2639 protein networkhttps://string-db.org/network/272631.gene:17576505Aldehyde dehydrogenase; Similar to many Prokaryotic and Eukaryotic aldehyde dehydrogenases including: Mycobacterium tuberculosis hypothetical 55.0 kda protein RV0147 TR:P96824 (EMBL:Z92770) fasta [...]
ML2640 protein networkhttps://string-db.org/network/272631.gene:17576506Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
ML2647 protein networkhttps://string-db.org/network/272631.gene:17576513Putative peptide methionine sulfoxide; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionin [...]
ML2649 protein networkhttps://string-db.org/network/272631.gene:17576515Hypothetical protein; Weakly similar to Streptomyces coelicolor putative oligosaccharide deacetylase TR:Q9RCX4 (EMBL:AL133469) fasta scores: E(): 4.5e-10, 30.9% in 165 aa, and to Bacillus cereus [...]
ML2654 protein networkhttps://string-db.org/network/272631.gene:17576520Conserved hypotehical protein; Similar to many proteins of undefined function e.g. Streptomyces coelicolor hypothetical 18.3 kda protein TR:Q9RJE5 (EMBL:AL133171) fasta scores: E(): 0, 60.1% in 1 [...]
fbpC2 protein networkhttps://string-db.org/network/272631.gene:17576521Secreted antigen 85A, mycolyltransferase; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria to fibronectin, a large adhesive glycoprotein, which fac [...]
ML2659 protein networkhttps://string-db.org/network/272631.gene:17576525Probable secreted serine protease; Similar to many including: Mycobacterium paratuberculosis 34 kda protein precursor TR:Q50320 (EMBL:Z23092) fasta scores: E(): 0, 71.4% in 364 aa, Mycobacterium [...]
ML2661 protein networkhttps://string-db.org/network/272631.gene:17576527acyl-CoA synthase; Similar to many Prokaryotic and Eukaryotic acyl-CoA synthases including: Mycobacterium tuberculosis fadd7 protein TR:O07169 (EMBL:Z96071) fasta scores: E(): 0, 71.3% in 520 aa, [...]
oxyS protein networkhttps://string-db.org/network/272631.gene:17576529Probable LysR family transcriptional regulator; Similar to Mycobacterium tuberculosis OxyS protein TR:O33175 (EMBL:AJ000188) fasta scores: E(): 0, 81.5% in 314 aa, and to Streptomyces coelicolor [...]
ML2664 protein networkhttps://string-db.org/network/272631.gene:17576530Possible secreted protein; Similar to Mycobacterium tuberculosis hypothetical 26.9 kda protein TR:O53638 (EMBL:AL021926) fasta scores: E(): 0, 76.0% in 250 aa, and to Streptomyces coelicolor puta [...]
ML2666 protein networkhttps://string-db.org/network/272631.gene:17576532Hypothetical protein; Function unknown.
ML2667 protein networkhttps://string-db.org/network/272631.gene:17576533Similar to Pseudomonas aeruginosa manganese transport protein MntH1 SW:MNT1_PSEAE (Q9RPF3) fasta scores: E(): 6.5e-13, 27.4% in 420 aa, and to Deinococcus radiodurans probable manganese transport [...]
ML2670 protein networkhttps://string-db.org/network/272631.gene:17576536Conserved integral membrane protein; Similar to Mycobacterium tuberculosis putative acetyltransferase TR:O53633 (EMBL:AL021926) fasta scores: E(): 0, 78.6% in 681 aa. Also similar to Salmonella t [...]
ML2671 protein networkhttps://string-db.org/network/272631.gene:17576537Similar to Mycobacterium tuberculosis probable cation-transporting ATPase I SW:CTPI_MYCTU (Q10900) fasta scores: E(): 0, 81.9% in 1573 aa, and the C-terminal region is similar to to Synechococcus [...]
icd2 protein networkhttps://string-db.org/network/272631.gene:17576538Isocitrate dehydrogenase [NADP]; EC_number=EC 1.1.1.42; Similar to Vibrio sp isocitrate dehydrogenase [NADP] 2 SW:IDH2_VIBA1 (P41561) fasta scores: E(): 0, 59.6% in 741 aa and to Mycobacterium tu [...]
ML2677 protein networkhttps://string-db.org/network/272631.gene:17576543Similar to several putative transcriptional regulators including: Mycobacterium tuberculosis transcriptional regulator Rv0078 TR:O53623 (EMBL:AL021428) fasta scores: E(): 0, 71.4% in 175 aa, and [...]
ML2678 protein networkhttps://string-db.org/network/272631.gene:17576544Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 124.5 kda protein cy9c4.02c TR:Q50732 (EMBL:Z77250) fasta scores: E(): 0, 50.3% in 1128 aa.
ML2679 protein networkhttps://string-db.org/network/272631.gene:17576545Conserved hypothetical protein; Similar in parts to many proteins of undefined function e.g. Mycobacterium tuberculosis hypothetical 95.4 kda protein rv2567 SW:YP67_MYCTU (Q50654; Q50731) fasta s [...]
dnaB protein networkhttps://string-db.org/network/272631.gene:17576546Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.
rplI protein networkhttps://string-db.org/network/272631.gene:1757654850S ribosomal protein L9; Binds to the 23S rRNA.
rpsR protein networkhttps://string-db.org/network/272631.gene:1757654930S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosom [...]
ssb protein networkhttps://string-db.org/network/272631.gene:17576550Similar to Escherichia coli single-strand binding protein SW:SSB_ECOLI (P02339) fasta scores: E(): 1.4e-09, 32.6% in 172 aa, and to Mycobacterium tuberculosis single-strand binding protein SW:SSB [...]
rpsF protein networkhttps://string-db.org/network/272631.gene:1757655130S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
ML2687 protein networkhttps://string-db.org/network/272631.gene:17576553Conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical 61.2 kda protein cy21d4.14 TR:P71708 (EMBL:Z80775) fasta scores: E(): 0, 78.7% in 531 aa, and to Streptomyces coelic [...]
ponA protein networkhttps://string-db.org/network/272631.gene:17576554Penicillin-bonding protein; Similar to Mycobacterium tuberculosis probable penicillin-binding proteins 1a/1b TR:P71707 (EMBL:Z80775) fasta scores: E(): 0, 82.6% in 679 aa, and to Bacillus subtili [...]
ML2689 protein networkhttps://string-db.org/network/272631.gene:17576555Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 15.0 kda protein Rv0049 SW:Y049_MYCTU (P71706) fasta scores: E(): 0, 83.2% in 137 aa.
ML2691 protein networkhttps://string-db.org/network/272631.gene:17576557Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 20.4 kda protein cy21d4.10c precursor TR:P71704 (EMBL:Z80775) fasta scores: E(): 0, 89.4% in 180 aa, and to Stre [...]
ML2692 protein networkhttps://string-db.org/network/272631.gene:17576558Similar to Mycobacterium tuberculosis hypothetical protein Rv0046c TR:P71703 (EMBL:Z80775) fasta scores: E(): 0, 91.8% in 366 aa, and to Streptomyces coelicolor hypothetical 39.2 kda protein TR:Q [...]
ML2696 protein networkhttps://string-db.org/network/272631.gene:17576562Putative MarR-family regulatory protein; Similar to Mycobacterium tuberculosis hypothetical 22.4 kda protein TR:P71699 (EMBL:Z80775) fasta scores: E(): 0, 77.4% in 190 aa, and weakly similar to S [...]
pcnA protein networkhttps://string-db.org/network/272631.gene:17576563pcnA; Similar to several polynucleotide polymerases (EC 2.7.7.19) including Mycobacterium tuberculosis TR:O05438 (EMBL:Z94121) fasta scores: E(): 0, 83.9% in 478 aa, and Bacillus subtilis poly SW [...]
ML2698 protein networkhttps://string-db.org/network/272631.gene:17576564Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 27.1 kda protein TR:O05437 (EMBL:Z94121) fasta scores: E(): 0, 78.6% in 248 aa. Contains Pfam match to entry PF0 [...]
ML2699 protein networkhttps://string-db.org/network/272631.gene:17576565Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 83.9 kda protein TR:O05436 (EMBL:Z94121) fasta scores: E(): 0, 72.4% in 803 aa. Contains a possible N-terminal signal [...]
ML2700 protein networkhttps://string-db.org/network/272631.gene:17576566Possible conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical 123.6 kda protein TR:O05435 (EMBL:Z94121) fasta scores: E(): 0, 75.1% in 1182 aa. Also the N-terminus is si [...]
trxB-2 protein networkhttps://string-db.org/network/272631.gene:17576569Bifunctional thioredoxin reductase/thioredoxin; EC_number=EC 1.6.4.5; Previously sequenced and characterised: Mycobacterium leprae bifunctional thioredoxin reductase/thioredoxin [includes: thiore [...]
ML2704 protein networkhttps://string-db.org/network/272631.gene:17576570Putative hydrolase; Similar to Mycobacterium tuberculosis putative hydrolase TR:O53593 (EMBL:AL021426) fasta scores: E(): 0, 86.9% in 406 aa. Contains 2 Pfam matches to entry PF01471 PG_binding_1 [...]
ML2705 protein networkhttps://string-db.org/network/272631.gene:17576571Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 26.6 kda protein Rv3916c TR:O53594 (EMBL:AL021426) fasta scores: E(): 0, 76.4% in 250 aa, and to Streptomyces co [...]
parB protein networkhttps://string-db.org/network/272631.gene:17576572Putative cell division protein; Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication [...]
parA protein networkhttps://string-db.org/network/272631.gene:17576573Putative cell division protein; Similar to many proteins thought to be involved with chromosome partitioning e.g. Mycobacterium tuberculosis hypothetical 37.5 kda protein TR:O53596 (EMBL:AL021426 [...]
ML2708 protein networkhttps://string-db.org/network/272631.gene:17576574Conserved hypothetical protein; Specifically methylates the N7 position of guanine in position 518 of 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
ML2709 protein networkhttps://string-db.org/network/272631.gene:17576575Conserved hypothetical protein; Similar to Mycobacterium paratuberculosis hypothetical 20.1 kda protein TR:AAF33691 (EMBL:AF222789) fasta scores: E(): 0, 76.0% in 183 aa, and to Mycobacterium tub [...]
ML2710 protein networkhttps://string-db.org/network/272631.gene:17576576Putative conserved membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane [...]
rnpA protein networkhttps://string-db.org/network/272631.gene:17576578Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. [...]
rpmH protein networkhttps://string-db.org/network/272631.gene:17576579Highly similar to many 50s ribosomal proteins (L34) e.g. Mycobacterium avium SW:RL34_MYCAV (Q9ZB91) (46 aa); Fasta score E(): 1.4e-15, 83.0% identity in 47 aa overlap and Mycobacterium tuberculos [...]