Organism Overview: Photodesmus katoptron


 
grpE protein networkhttps://string-db.org/network/28176.CF66_0101Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the n [...]
dnaK protein networkhttps://string-db.org/network/28176.CF66_0102Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
dnaL protein networkhttps://string-db.org/network/28176.CF66_0103Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an auton [...]
tadA protein networkhttps://string-db.org/network/28176.CF66_0104tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
purL protein networkhttps://string-db.org/network/28176.CF66_0105Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ri [...]
proS protein networkhttps://string-db.org/network/28176.CF66_0106prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
dxs protein networkhttps://string-db.org/network/28176.CF66_01071-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (D [...]
ispA protein networkhttps://string-db.org/network/28176.CF66_0108Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
xseB protein networkhttps://string-db.org/network/28176.CF66_0109Exodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleo [...]
pomA protein networkhttps://string-db.org/network/28176.CF66_0110Flagellar motor protein.
motB protein networkhttps://string-db.org/network/28176.CF66_0112Flagellar motor protein.
thiI protein networkhttps://string-db.org/network/28176.CF66_0113tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the tran [...]
gmhB protein networkhttps://string-db.org/network/28176.CF66_0114D,D-heptose 1,7-bisphosphate phosphatase.
CF66_0115 protein networkhttps://string-db.org/network/28176.CF66_0115Membrane protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
CF66_0116 protein networkhttps://string-db.org/network/28176.CF66_0116Membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
glyA protein networkhttps://string-db.org/network/28176.CF66_0117Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
lipA protein networkhttps://string-db.org/network/28176.CF66_0118Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, there [...]
lipB protein networkhttps://string-db.org/network/28176.CF66_0119Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also ac [...]
dacC protein networkhttps://string-db.org/network/28176.CF66_0121D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
rlpA protein networkhttps://string-db.org/network/28176.CF66_0122rlpA-like lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
rodA protein networkhttps://string-db.org/network/28176.CF66_0123Rod shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
mrdA protein networkhttps://string-db.org/network/28176.CF66_0124Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
holA protein networkhttps://string-db.org/network/28176.CF66_0125DNA polymerase III subunit delta.
lptE protein networkhttps://string-db.org/network/28176.CF66_0126LPS-assembly lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and [...]
leuS protein networkhttps://string-db.org/network/28176.CF66_0128leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
lnt protein networkhttps://string-db.org/network/28176.CF66_0129Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrol [...]
corC protein networkhttps://string-db.org/network/28176.CF66_0130Magnesium and cobalt efflux protein.
ybeY protein networkhttps://string-db.org/network/28176.CF66_0131Putative rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
miaB protein networkhttps://string-db.org/network/28176.CF66_0132(dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine ( [...]
ubiF protein networkhttps://string-db.org/network/28176.CF66_01332-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
ptgA protein networkhttps://string-db.org/network/28176.CF66_0135Glucose-specific phosphotransferase enzyme IIA component.
ptsI protein networkhttps://string-db.org/network/28176.CF66_0136Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate ac [...]
ptsH protein networkhttps://string-db.org/network/28176.CF66_0137Phosphocarrier protein.
zipA protein networkhttps://string-db.org/network/28176.CF66_0139Cell division protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required [...]
ligA protein networkhttps://string-db.org/network/28176.CF66_0140DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy sourc [...]
grxD protein networkhttps://string-db.org/network/28176.CF66_0141Glutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily.
sodB protein networkhttps://string-db.org/network/28176.CF66_0142Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
rne protein networkhttps://string-db.org/network/28176.CF66_0143Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation [...]
rluC protein networkhttps://string-db.org/network/28176.CF66_0144Ribosomal large subunit pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
asd1 protein networkhttps://string-db.org/network/28176.CF66_0145Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family.
CF66_0146 protein networkhttps://string-db.org/network/28176.CF66_0146Oligoendopeptidase F.
CF66_0147 protein networkhttps://string-db.org/network/28176.CF66_0147Conserved conserved hypothetical protein.
wcaJ protein networkhttps://string-db.org/network/28176.CF66_0148Putative colanic biosynthesis UDP-glucose lipid carrier transferase.
CF66_0149 protein networkhttps://string-db.org/network/28176.CF66_0149Glycotransferase.
CF66_0150 protein networkhttps://string-db.org/network/28176.CF66_0150Glycosyltransferase.
CF66_0151 protein networkhttps://string-db.org/network/28176.CF66_0151Chain length determinant protein.
CF66_0153 protein networkhttps://string-db.org/network/28176.CF66_0153Putative glycosyltransferase.
exoQ protein networkhttps://string-db.org/network/28176.CF66_0155Exopolysaccharide production protein.
exoT protein networkhttps://string-db.org/network/28176.CF66_0157Succinoglycan biosynthesis transport protein.
CF66_0158 protein networkhttps://string-db.org/network/28176.CF66_0158Lipopolysaccharide synthesis protein.
CF66_0159 protein networkhttps://string-db.org/network/28176.CF66_0159Glycosyltransferase.
ispD protein networkhttps://string-db.org/network/28176.CF66_0160Glycosyltransferase.
CF66_0162 protein networkhttps://string-db.org/network/28176.CF66_0162Chromosome partitioning ATPase.
CF66_0163 protein networkhttps://string-db.org/network/28176.CF66_0163Polysaccharide export protein.
paI protein networkhttps://string-db.org/network/28176.CF66_0165Peptidoglycan-associated lipoprotein.
spoIIAA protein networkhttps://string-db.org/network/28176.CF66_0166Anti-sigma F factor regulatory protein.
norM protein networkhttps://string-db.org/network/28176.CF66_0167Multidrug resistance protein.
ribE protein networkhttps://string-db.org/network/28176.CF66_0168Riboflavin synthase alpha chain.
topA protein networkhttps://string-db.org/network/28176.CF66_0170DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of [...]
aroA protein networkhttps://string-db.org/network/28176.CF66_01713-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
infA protein networkhttps://string-db.org/network/28176.CF66_0172Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
cysS protein networkhttps://string-db.org/network/28176.CF66_0173cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
ipxH protein networkhttps://string-db.org/network/28176.CF66_0174UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water [...]
cmoB protein networkhttps://string-db.org/network/28176.CF66_0175tRNA (mo5U34)-methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 [...]
cmoA protein networkhttps://string-db.org/network/28176.CF66_0177tRNA (cmo5U34)-methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
aspS protein networkhttps://string-db.org/network/28176.CF66_0178aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor [...]
ruvC protein networkhttps://string-db.org/network/28176.CF66_0179Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands [...]
ruvA protein networkhttps://string-db.org/network/28176.CF66_0180Holliday junction ATP-dependent DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promo [...]
ruvB protein networkhttps://string-db.org/network/28176.CF66_0181Holliday junction ATP-dependent DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promo [...]
tolQ protein networkhttps://string-db.org/network/28176.CF66_0183Protein tolQ.
tolR protein networkhttps://string-db.org/network/28176.CF66_0184Protein tolR.
fusA1 protein networkhttps://string-db.org/network/28176.CF66_1001Elongation factor G 1; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the pos [...]
rpsG protein networkhttps://string-db.org/network/28176.CF66_100230S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit inte [...]
rpsL protein networkhttps://string-db.org/network/28176.CF66_100330S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S an [...]
tusB protein networkhttps://string-db.org/network/28176.CF66_1004tusB protein.
tusC protein networkhttps://string-db.org/network/28176.CF66_1005Protein TusC; Belongs to the DsrF/TusC family.
tusD protein networkhttps://string-db.org/network/28176.CF66_1006Sulfurtransferase TusD.
fkpA protein networkhttps://string-db.org/network/28176.CF66_1007FKBP-type peptidyl-prolyl cis-trans isomerase fkpA.
hflC protein networkhttps://string-db.org/network/28176.CF66_1008Protein HflC; HflC and HflK could regulate a protease.
hflK protein networkhttps://string-db.org/network/28176.CF66_1009Protein HflK; HflC and HflK could encode or regulate a protease.
miaA protein networkhttps://string-db.org/network/28176.CF66_1010tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(di [...]
mutL protein networkhttps://string-db.org/network/28176.CF66_1012DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchm [...]
amiB protein networkhttps://string-db.org/network/28176.CF66_1013N-acetylmuramoyl-L-alanine amidase.
yjE protein networkhttps://string-db.org/network/28176.CF66_1014ATP-binding protein yjeE.
CF66_1015 protein networkhttps://string-db.org/network/28176.CF66_1015Cytochrome c5.
hemE protein networkhttps://string-db.org/network/28176.CF66_1016Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
orn protein networkhttps://string-db.org/network/28176.CF66_1017Ligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
psd protein networkhttps://string-db.org/network/28176.CF66_1018Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
CF66_1019 protein networkhttps://string-db.org/network/28176.CF66_1019Putative protease.
rmuC protein networkhttps://string-db.org/network/28176.CF66_1020DNA recombination protein rmuC.
ubiE protein networkhttps://string-db.org/network/28176.CF66_1021Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-m [...]
CF66_1022 protein networkhttps://string-db.org/network/28176.CF66_1022Hypothetical protein.
yfhL protein networkhttps://string-db.org/network/28176.CF66_1023Ferrodoxin.
ubiB protein networkhttps://string-db.org/network/28176.CF66_1024Ubiquinone biosynthesis protein UbiB.
tatA protein networkhttps://string-db.org/network/28176.CF66_1025Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their s [...]
tatC protein networkhttps://string-db.org/network/28176.CF66_1028Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their s [...]
yabD protein networkhttps://string-db.org/network/28176.CF66_1029Deoxyribonuclease YabD.
hemB protein networkhttps://string-db.org/network/28176.CF66_1030Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
polA protein networkhttps://string-db.org/network/28176.CF66_1032DNA polymerase I.
engB protein networkhttps://string-db.org/network/28176.CF66_1033GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPas [...]
cc4 protein networkhttps://string-db.org/network/28176.CF66_1034Cytochrome c4.
hemN protein networkhttps://string-db.org/network/28176.CF66_1035Oxygen-independent coproporphyrinogen-III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
CF66_1036 protein networkhttps://string-db.org/network/28176.CF66_1036Hypothetical protein.
ampP protein networkhttps://string-db.org/network/28176.CF66_1037Xaa-Pro aminopeptidase P.
dnaA protein networkhttps://string-db.org/network/28176.CF66_1101Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically doub [...]
dnaN protein networkhttps://string-db.org/network/28176.CF66_1102DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadin [...]
recF protein networkhttps://string-db.org/network/28176.CF66_1103DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-strand [...]
gyrB protein networkhttps://string-db.org/network/28176.CF66_1104DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
glyS protein networkhttps://string-db.org/network/28176.CF66_1105glycyl-tRNA synthetase beta subunit.
glyQ protein networkhttps://string-db.org/network/28176.CF66_1107glycyl-tRNA synthetase alpha subunit.
aroE protein networkhttps://string-db.org/network/28176.CF66_1201Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshiki [...]
rimN protein networkhttps://string-db.org/network/28176.CF66_1202tRNA threonylcarbamoyladenosine biosynthesis protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenin [...]
purE protein networkhttps://string-db.org/network/28176.CF66_1203N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
purK protein networkhttps://string-db.org/network/28176.CF66_1204N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR [...]
tuF2 protein networkhttps://string-db.org/network/28176.CF66_1501Elongation factor Tu 2; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
pgpA protein networkhttps://string-db.org/network/28176.CF66_2001Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
map protein networkhttps://string-db.org/network/28176.CF66_2002Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharg [...]
rpsB protein networkhttps://string-db.org/network/28176.CF66_200330S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
tsf protein networkhttps://string-db.org/network/28176.CF66_2004Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the [...]
pyrH protein networkhttps://string-db.org/network/28176.CF66_2005Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
frr protein networkhttps://string-db.org/network/28176.CF66_2006Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
uppS protein networkhttps://string-db.org/network/28176.CF66_2007Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E [...]
cdsA protein networkhttps://string-db.org/network/28176.CF66_2008Phosphatidate cytidylyltransferase; Belongs to the CDS family.
dxr protein networkhttps://string-db.org/network/28176.CF66_20091-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Be [...]
CF66_2010 protein networkhttps://string-db.org/network/28176.CF66_2010Zinc metalloprotease.
yaeT protein networkhttps://string-db.org/network/28176.CF66_2011Outer membrane protein assembly factor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
skp protein networkhttps://string-db.org/network/28176.CF66_2012Chaperone protein.
ipxD protein networkhttps://string-db.org/network/28176.CF66_2014UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lip [...]
fabZ protein networkhttps://string-db.org/network/28176.CF66_2015(3R)-hydroxymyristoyl-acyl-carrier-protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated a [...]
ipxA protein networkhttps://string-db.org/network/28176.CF66_2016acyl[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membra [...]
ipxB protein networkhttps://string-db.org/network/28176.CF66_2017lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid t [...]
rnhB protein networkhttps://string-db.org/network/28176.CF66_2018Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
dnaE protein networkhttps://string-db.org/network/28176.CF66_2020DNA polymerase III subunit alpha.
accA protein networkhttps://string-db.org/network/28176.CF66_2021Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on [...]
tilS protein networkhttps://string-db.org/network/28176.CF66_2022tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is c [...]
flhB protein networkhttps://string-db.org/network/28176.CF66_2023Flagellar biosynthetic protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flage [...]
fliR protein networkhttps://string-db.org/network/28176.CF66_2024Flagellar biosynthetic protein; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.
fliQ protein networkhttps://string-db.org/network/28176.CF66_2025Flagellar biosynthesis protein fliQ.
fliP protein networkhttps://string-db.org/network/28176.CF66_2027Flagellar biosynthetic protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
fliO protein networkhttps://string-db.org/network/28176.CF66_2028Flagellar protein.
fliN protein networkhttps://string-db.org/network/28176.CF66_2029Flagellar motor switch protein; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts [...]
fliM protein networkhttps://string-db.org/network/28176.CF66_2030Flagellar motor switch protein; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interact [...]
fliK protein networkhttps://string-db.org/network/28176.CF66_2031Flagellar hook-length control protein.
fliJ protein networkhttps://string-db.org/network/28176.CF66_2032Flagellar protein.
fliI protein networkhttps://string-db.org/network/28176.CF66_2033Flagellum-specific ATP synthase.
fliH protein networkhttps://string-db.org/network/28176.CF66_2034Flagellar assembly protein.
fliG protein networkhttps://string-db.org/network/28176.CF66_2035Flagellar motor switch protein; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interact [...]
fliF protein networkhttps://string-db.org/network/28176.CF66_2036Flagellar M-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
fliE protein networkhttps://string-db.org/network/28176.CF66_2037Flagellar hook-basal body complex protein.
flaK protein networkhttps://string-db.org/network/28176.CF66_2039Polar flagellar protein.
fliS protein networkhttps://string-db.org/network/28176.CF66_2040Flagellar protein.
flaI protein networkhttps://string-db.org/network/28176.CF66_2041Flagellar rod protein.
fliD protein networkhttps://string-db.org/network/28176.CF66_2042Flagellar hook-associated protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filam [...]
flaG protein networkhttps://string-db.org/network/28176.CF66_2043Protein flaG.
ssb protein networkhttps://string-db.org/network/28176.CF66_2044Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of act [...]
nqrA protein networkhttps://string-db.org/network/28176.CF66_2046Na(+)-translocating NADH-quinone reductase subunit A; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from t [...]
nqrB protein networkhttps://string-db.org/network/28176.CF66_2047Na(+)-translocating NADH-quinone reductase subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from t [...]
nqrc protein networkhttps://string-db.org/network/28176.CF66_2048Na(+)-translocating NADH-quinone reductase subunit C; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from t [...]
nqrD protein networkhttps://string-db.org/network/28176.CF66_2049Na(+)-translocating NADH-quinone reductase subunit D; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from t [...]
nqrE protein networkhttps://string-db.org/network/28176.CF66_2050Na(+)-translocating NADH-quinone reductase subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from t [...]
nqrF protein networkhttps://string-db.org/network/28176.CF66_2051Na(+)-translocating NADH-quinone reductase subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from t [...]
apbE protein networkhttps://string-db.org/network/28176.CF66_2052Thiamine biosynthesis lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavop [...]
CF66_2053 protein networkhttps://string-db.org/network/28176.CF66_2053Hypothetical protein.
perM protein networkhttps://string-db.org/network/28176.CF66_2054Permease.
ddI protein networkhttps://string-db.org/network/28176.CF66_2055D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
dapA protein networkhttps://string-db.org/network/28176.CF66_2056Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
CF66_2057 protein networkhttps://string-db.org/network/28176.CF66_2057Thioredoxin peroxidase.
pgk protein networkhttps://string-db.org/network/28176.CF66_2058Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
fba protein networkhttps://string-db.org/network/28176.CF66_2059Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphat [...]
galE protein networkhttps://string-db.org/network/28176.CF66_2060UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
clpP protein networkhttps://string-db.org/network/28176.CF66_2062ATP-dependent Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded pr [...]
dapE protein networkhttps://string-db.org/network/28176.CF66_2063Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in [...]
recC protein networkhttps://string-db.org/network/28176.CF66_2064Exodeoxyribonuclease V gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-depend [...]
recB protein networkhttps://string-db.org/network/28176.CF66_2065Exodeoxyribonuclease V beta chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-depende [...]
recD protein networkhttps://string-db.org/network/28176.CF66_2066exodeoxyribonucleaseV alpha chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-depende [...]
nhaB protein networkhttps://string-db.org/network/28176.CF66_2068Na(+)/H(+) antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
ftsK protein networkhttps://string-db.org/network/28176.CF66_2069DNA translocase; Belongs to the FtsK/SpoIIIE/SftA family.
lrp protein networkhttps://string-db.org/network/28176.CF66_2070Leucine-responsive regulatory protein.
panE protein networkhttps://string-db.org/network/28176.CF66_20712-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
nadC protein networkhttps://string-db.org/network/28176.CF66_2072Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
xerD protein networkhttps://string-db.org/network/28176.CF66_2073Tyrosine recombinase.
recJ protein networkhttps://string-db.org/network/28176.CF66_2074single-stranded-DNA-specific exonuclease.
aceE protein networkhttps://string-db.org/network/28176.CF66_2076Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
aceF protein networkhttps://string-db.org/network/28176.CF66_2077Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
ipd protein networkhttps://string-db.org/network/28176.CF66_2078Dihydrolipoyl dehydrogenase.
ackA1 protein networkhttps://string-db.org/network/28176.CF66_2079Acetate kinase 1; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
pta protein networkhttps://string-db.org/network/28176.CF66_2080Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
groS protein networkhttps://string-db.org/network/28176.CF66_208210 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
groL1 protein networkhttps://string-db.org/network/28176.CF66_208360 kDa chaperonin 1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
gltX protein networkhttps://string-db.org/network/28176.CF66_2085glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
copA protein networkhttps://string-db.org/network/28176.CF66_2086Copper-translocating P-type ATPase.
fadR protein networkhttps://string-db.org/network/28176.CF66_2087Fatty acid metabolism regulator protein; Multifunctional regulator of fatty acid metabolism.
zapB protein networkhttps://string-db.org/network/28176.CF66_2088Cell division protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulatin [...]
CF66_2089 protein networkhttps://string-db.org/network/28176.CF66_2089Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
luxR protein networkhttps://string-db.org/network/28176.CF66_2090Transcriptional regulator.
vvpD protein networkhttps://string-db.org/network/28176.CF66_2091Type 4 prepilin-like proteins leader peptide-processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
coaE protein networkhttps://string-db.org/network/28176.CF66_2092dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
rplS protein networkhttps://string-db.org/network/28176.CF66_209350S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
trmD protein networkhttps://string-db.org/network/28176.CF66_2094tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rimM protein networkhttps://string-db.org/network/28176.CF66_2095Ribosome maturation factor; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Esse [...]
rpsP protein networkhttps://string-db.org/network/28176.CF66_209630S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
ffh protein networkhttps://string-db.org/network/28176.CF66_2097Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascen [...]
ypjD protein networkhttps://string-db.org/network/28176.CF66_2098Inner membrane protein.
yfjD protein networkhttps://string-db.org/network/28176.CF66_2099Inner membrane protein.
dksA protein networkhttps://string-db.org/network/28176.CF66_2100dnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several am [...]
gshA protein networkhttps://string-db.org/network/28176.CF66_2101Glutamate-cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
CF66_2102 protein networkhttps://string-db.org/network/28176.CF66_2102Hypothetical protein.
CF66_2103 protein networkhttps://string-db.org/network/28176.CF66_2103Hypothetical protein.
CF66_2104 protein networkhttps://string-db.org/network/28176.CF66_2104Hypothetical protein.
secB protein networkhttps://string-db.org/network/28176.CF66_2105Protein-export protein; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, main [...]
gpsA protein networkhttps://string-db.org/network/28176.CF66_2106Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
crp protein networkhttps://string-db.org/network/28176.CF66_2107Catabolite gene activator.
pabA protein networkhttps://string-db.org/network/28176.CF66_2108Para-aminobenzoate synthase glutamine amidotransferase component II.
truB protein networkhttps://string-db.org/network/28176.CF66_2110tRNA pseudouridine synthase B; Belongs to the pseudouridine synthase TruB family.
rbfA protein networkhttps://string-db.org/network/28176.CF66_2111Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
infB protein networkhttps://string-db.org/network/28176.CF66_2112Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
nusA protein networkhttps://string-db.org/network/28176.CF66_2113Transcription elongation protein; Participates in both transcription termination and antitermination.
rimP protein networkhttps://string-db.org/network/28176.CF66_2114Ribosome maturation factor; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
secG protein networkhttps://string-db.org/network/28176.CF66_2115Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
glmM protein networkhttps://string-db.org/network/28176.CF66_2116Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
folP protein networkhttps://string-db.org/network/28176.CF66_2117Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate [...]
ftsH protein networkhttps://string-db.org/network/28176.CF66_2118ATP-dependent zinc metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane [...]
rlmE protein networkhttps://string-db.org/network/28176.CF66_2119Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
greA protein networkhttps://string-db.org/network/28176.CF66_2120Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a [...]
pssA protein networkhttps://string-db.org/network/28176.CF66_2122CDP-diacylglycerol-serine O-phosphatidyltransferase.
murB protein networkhttps://string-db.org/network/28176.CF66_2123UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
birA protein networkhttps://string-db.org/network/28176.CF66_2125Bifunctional protein.
glmS protein networkhttps://string-db.org/network/28176.CF66_2126Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
pykF protein networkhttps://string-db.org/network/28176.CF66_2128Pyruvate kinase I; Belongs to the pyruvate kinase family.
nadE protein networkhttps://string-db.org/network/28176.CF66_2130NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
nadD protein networkhttps://string-db.org/network/28176.CF66_2131Nicotinate-nucleotide adenylyltransferase; Belongs to the NadD family.
CF66_2132 protein networkhttps://string-db.org/network/28176.CF66_2132Deaminase.
mgtE protein networkhttps://string-db.org/network/28176.CF66_2133Magnesium transporter.
apt protein networkhttps://string-db.org/network/28176.CF66_2134Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
dnaX protein networkhttps://string-db.org/network/28176.CF66_2135DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuc [...]
recR protein networkhttps://string-db.org/network/28176.CF66_2137Recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
pgs1 protein networkhttps://string-db.org/network/28176.CF66_2138CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase.
mfd protein networkhttps://string-db.org/network/28176.CF66_2140Transcription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated tr [...]
CF66_2142 protein networkhttps://string-db.org/network/28176.CF66_2142Hypothetical protein.
lolC protein networkhttps://string-db.org/network/28176.CF66_2143Lipoprotein-releasing system transmembrane protein.
lolD protein networkhttps://string-db.org/network/28176.CF66_2144Lipoprotein-releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.
lolE protein networkhttps://string-db.org/network/28176.CF66_2145Lipoprotein-releasing system transmembrane protein.
aroK protein networkhttps://string-db.org/network/28176.CF66_2147Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
aroB protein networkhttps://string-db.org/network/28176.CF66_21483-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
damX protein networkhttps://string-db.org/network/28176.CF66_2150DamX protein.
dam protein networkhttps://string-db.org/network/28176.CF66_2151DNA adenine methylase.
rpe protein networkhttps://string-db.org/network/28176.CF66_2152Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
hldE protein networkhttps://string-db.org/network/28176.CF66_2153Bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the ca [...]
tolC protein networkhttps://string-db.org/network/28176.CF66_2154Outer membrane protein.
cpdA protein networkhttps://string-db.org/network/28176.CF66_21553',5'-cyclic adenosine monophosphate phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cA [...]
msbA protein networkhttps://string-db.org/network/28176.CF66_2157Lipid A export ATP-binding/permease protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form [...]
ipxK protein networkhttps://string-db.org/network/28176.CF66_2158Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis [...]
CF66_2159 protein networkhttps://string-db.org/network/28176.CF66_2159Hypothetical protein.
kdsB protein networkhttps://string-db.org/network/28176.CF66_21603-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
CF66_2161 protein networkhttps://string-db.org/network/28176.CF66_2161Hypothetical protein.
CF66_2162 protein networkhttps://string-db.org/network/28176.CF66_2162Hypothetical protein; Belongs to the UPF0229 family.
CF66_2163 protein networkhttps://string-db.org/network/28176.CF66_2163Hypothetical protein.
yebA protein networkhttps://string-db.org/network/28176.CF66_2164Metalloprotease.
tyrS2 protein networkhttps://string-db.org/network/28176.CF66_2165tyrosyl-tRNA synthetase 2; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end o [...]
icd2 protein networkhttps://string-db.org/network/28176.CF66_2167Isocitrate dehydrogenase 2; Belongs to the monomeric-type IDH family.
clpA protein networkhttps://string-db.org/network/28176.CF66_2168ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family.
CF66_2169 protein networkhttps://string-db.org/network/28176.CF66_2169Membrane protein.
htpG protein networkhttps://string-db.org/network/28176.CF66_2170Chaperone protein; Molecular chaperone. Has ATPase activity.
adk protein networkhttps://string-db.org/network/28176.CF66_2171Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
hemH protein networkhttps://string-db.org/network/28176.CF66_2172Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
fusA2 protein networkhttps://string-db.org/network/28176.CF66_2174Elongation factor G 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the pos [...]
radA protein networkhttps://string-db.org/network/28176.CF66_2175DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand trans [...]
thiK protein networkhttps://string-db.org/network/28176.CF66_2176Thiamine kinase.
rplY protein networkhttps://string-db.org/network/28176.CF66_217750S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 fa [...]
CF66_2178 protein networkhttps://string-db.org/network/28176.CF66_2178BCCT transporter; Belongs to the BCCT transporter (TC 2.A.15) family.
degQ protein networkhttps://string-db.org/network/28176.CF66_2179Protease; Belongs to the peptidase S1C family.
CF66_2180 protein networkhttps://string-db.org/network/28176.CF66_2180Hypothetical protein.
rplM protein networkhttps://string-db.org/network/28176.CF66_218150S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages [...]
rpsI protein networkhttps://string-db.org/network/28176.CF66_218230S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
petA protein networkhttps://string-db.org/network/28176.CF66_2184Ubiquinol-cytochrome c reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generat [...]
petB protein networkhttps://string-db.org/network/28176.CF66_2185Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled [...]
petC protein networkhttps://string-db.org/network/28176.CF66_2186Cytochrome c1.
sspA protein networkhttps://string-db.org/network/28176.CF66_2187Stringent starvation protein A.
sspB protein networkhttps://string-db.org/network/28176.CF66_2188Stringent starvation protein B.
CF66_2189 protein networkhttps://string-db.org/network/28176.CF66_218925 kDa hemolysin.
diaA protein networkhttps://string-db.org/network/28176.CF66_2190dnaA initiator-associating protein; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
lpoA protein networkhttps://string-db.org/network/28176.CF66_2191Penicillin-binding protein activator.
rsmI protein networkhttps://string-db.org/network/28176.CF66_2192Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
parC protein networkhttps://string-db.org/network/28176.CF66_2193DNA topoisomerase 4 subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular [...]
parE protein networkhttps://string-db.org/network/28176.CF66_2194DNA topoisomerase 4 subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular [...]
gyrA protein networkhttps://string-db.org/network/28176.CF66_2195DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
ubiG protein networkhttps://string-db.org/network/28176.CF66_21963-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG [...]
sppA protein networkhttps://string-db.org/network/28176.CF66_2197Protease 4.
nrdA protein networkhttps://string-db.org/network/28176.CF66_2201Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
nrdB protein networkhttps://string-db.org/network/28176.CF66_2202Ribonucleoside-diphosphate reductase 1 subunit beta.
CF66_2203 protein networkhttps://string-db.org/network/28176.CF66_2203Hypothetical protein.
folB protein networkhttps://string-db.org/network/28176.CF66_2204Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
uppP protein networkhttps://string-db.org/network/28176.CF66_2206Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
ftsB protein networkhttps://string-db.org/network/28176.CF66_2207Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, whi [...]
ispD-2 protein networkhttps://string-db.org/network/28176.CF66_22082-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
ispF protein networkhttps://string-db.org/network/28176.CF66_22092-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid [...]
nlpD protein networkhttps://string-db.org/network/28176.CF66_2210Urein hydrolase activator.
rpoS protein networkhttps://string-db.org/network/28176.CF66_2211Polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master tra [...]
mutS protein networkhttps://string-db.org/network/28176.CF66_2212DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity [...]
recA protein networkhttps://string-db.org/network/28176.CF66_2213Recombinase; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homo [...]
gcp protein networkhttps://string-db.org/network/28176.CF66_2214tRNA threonylcarbamoyladenosine biosynthesis protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenin [...]
rpsU protein networkhttps://string-db.org/network/28176.CF66_221530S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
dnaG protein networkhttps://string-db.org/network/28176.CF66_2216DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpoD protein networkhttps://string-db.org/network/28176.CF66_2217RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primar [...]
folD protein networkhttps://string-db.org/network/28176.CF66_2218Bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofo [...]
CF66_2219 protein networkhttps://string-db.org/network/28176.CF66_2219Hypothetical protein.
CF66_2220 protein networkhttps://string-db.org/network/28176.CF66_2220Hypothetical protein.
trpS protein networkhttps://string-db.org/network/28176.CF66_2221tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
arcA protein networkhttps://string-db.org/network/28176.CF66_2222Arginine deiminase 2.
CF66_2223 protein networkhttps://string-db.org/network/28176.CF66_2223Manganese-dependent inorganic pyrophosphatase.
argS protein networkhttps://string-db.org/network/28176.CF66_2224arginyl-tRNA synthetase.
mreB protein networkhttps://string-db.org/network/28176.CF66_2225Rod shape-determining protein.
mreC protein networkhttps://string-db.org/network/28176.CF66_2226Rod shape-determining protein; Involved in formation and maintenance of cell shape.
mreD protein networkhttps://string-db.org/network/28176.CF66_2227Rod shape-determining protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.
rng protein networkhttps://string-db.org/network/28176.CF66_2228Ribonuclease G.
CF66_2229 protein networkhttps://string-db.org/network/28176.CF66_2229Hypothetical protein.
CF66_2230 protein networkhttps://string-db.org/network/28176.CF66_2230Zn-dependent protease.
rsmH protein networkhttps://string-db.org/network/28176.CF66_2231Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
ftsL protein networkhttps://string-db.org/network/28176.CF66_2232Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, whi [...]
ftsI protein networkhttps://string-db.org/network/28176.CF66_2233Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
murE protein networkhttps://string-db.org/network/28176.CF66_2234UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (U [...]
murF protein networkhttps://string-db.org/network/28176.CF66_2235UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of mure [...]
mraY protein networkhttps://string-db.org/network/28176.CF66_2236phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY s [...]
murD protein networkhttps://string-db.org/network/28176.CF66_2237UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF [...]
ftsW protein networkhttps://string-db.org/network/28176.CF66_2238Cell division protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
murG protein networkhttps://string-db.org/network/28176.CF66_2239Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
murC protein networkhttps://string-db.org/network/28176.CF66_2240UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
ftsQ protein networkhttps://string-db.org/network/28176.CF66_2241Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, whi [...]
ftsA protein networkhttps://string-db.org/network/28176.CF66_2242Cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
ftsZ protein networkhttps://string-db.org/network/28176.CF66_2243Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing a [...]
ipxC protein networkhttps://string-db.org/network/28176.CF66_2244UDP-3-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthe [...]
CF66_2245 protein networkhttps://string-db.org/network/28176.CF66_2245Hypothetical protein.
secA protein networkhttps://string-db.org/network/28176.CF66_2246Protein translocase subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the tran [...]
mutT protein networkhttps://string-db.org/network/28176.CF66_2247Mutator protein; Belongs to the Nudix hydrolase family.
dapB protein networkhttps://string-db.org/network/28176.CF66_2248Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
carA protein networkhttps://string-db.org/network/28176.CF66_2249Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.
carB protein networkhttps://string-db.org/network/28176.CF66_2250Carbamoyl-phosphate synthase large chain; Belongs to the CarB family.
rps protein networkhttps://string-db.org/network/28176.CF66_225130S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
pnp protein networkhttps://string-db.org/network/28176.CF66_2252Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
flhA protein networkhttps://string-db.org/network/28176.CF66_2253Flagellar biosynthesis protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to t [...]
flhF protein networkhttps://string-db.org/network/28176.CF66_2254Flagellar biosynthesis protein.
flhG protein networkhttps://string-db.org/network/28176.CF66_2255Flagellar biosynthesis protein.
cheY protein networkhttps://string-db.org/network/28176.CF66_2257Chemotaxis protein.
cheZ protein networkhttps://string-db.org/network/28176.CF66_2258Chemotaxis phosphatase; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).
cheA protein networkhttps://string-db.org/network/28176.CF66_2259Chemotaxis protein.
cheB1 protein networkhttps://string-db.org/network/28176.CF66_2261Chemotaxis response regulator protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylatio [...]
parA protein networkhttps://string-db.org/network/28176.CF66_2262Replication initiation protein.
CF66_2263 protein networkhttps://string-db.org/network/28176.CF66_2263Hypothetical protein.
cheW protein networkhttps://string-db.org/network/28176.CF66_2264Chemotaxis protein.
CF66_2265 protein networkhttps://string-db.org/network/28176.CF66_2265DNA repair ATPase.
ccmA protein networkhttps://string-db.org/network/28176.CF66_2266Cytochrome c biogenesis ATP-binding export protein; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be t [...]
ccmB protein networkhttps://string-db.org/network/28176.CF66_2267Heme exporter protein B.
ccmC protein networkhttps://string-db.org/network/28176.CF66_2268Heme exporter protein C; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
ccmD protein networkhttps://string-db.org/network/28176.CF66_2269Heme exporter protein D; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
ccmE protein networkhttps://string-db.org/network/28176.CF66_2270Cytochrome c-type biogenesis protein E; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a p [...]
ccmF protein networkhttps://string-db.org/network/28176.CF66_2273Cytochrome c-type biogenesis protein F.
dsbE protein networkhttps://string-db.org/network/28176.CF66_2274Thiol:disulfide interchange protein.
ccmL protein networkhttps://string-db.org/network/28176.CF66_2275Cytochrome c-type biogenesis protein L; Possible subunit of a heme lyase.
ccmH protein networkhttps://string-db.org/network/28176.CF66_2276Cytochrome c-type biogenesis protein H.
vacJ protein networkhttps://string-db.org/network/28176.CF66_2277Phospholipid-binding lipoprotein.
purC protein networkhttps://string-db.org/network/28176.CF66_2280Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family.
CF66_2281 protein networkhttps://string-db.org/network/28176.CF66_2281Hypothetical protein.
glnS protein networkhttps://string-db.org/network/28176.CF66_2282glutaminyl-tRNA synthetase.
fabV protein networkhttps://string-db.org/network/28176.CF66_2285Putative reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is co [...]
ynaI protein networkhttps://string-db.org/network/28176.CF66_2286Inner membrane protein.
CF66_2287 protein networkhttps://string-db.org/network/28176.CF66_2287Hypothetical protein.
hns protein networkhttps://string-db.org/network/28176.CF66_2288DNA-binding protein H-NS; Belongs to the histone-like protein H-NS family.
pgsA protein networkhttps://string-db.org/network/28176.CF66_2289CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
CF66_2290 protein networkhttps://string-db.org/network/28176.CF66_2290Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
mrcA protein networkhttps://string-db.org/network/28176.CF66_2291Penicillin-binding protein 1A.
CF66_2293 protein networkhttps://string-db.org/network/28176.CF66_2293MATE efflux protein.
metG protein networkhttps://string-db.org/network/28176.CF66_2294methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
phaB protein networkhttps://string-db.org/network/28176.CF66_2295acetoacetyl-CoA reductase.
atoB protein networkhttps://string-db.org/network/28176.CF66_2296acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
CF66_2297 protein networkhttps://string-db.org/network/28176.CF66_2297Phasin protein.
phaC protein networkhttps://string-db.org/network/28176.CF66_2298poly(R)-hydroxyalkanoic acid synthase.
fldA protein networkhttps://string-db.org/network/28176.CF66_2300Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
ycnJ protein networkhttps://string-db.org/network/28176.CF66_2301Copper transport protein.
CF66_2302 protein networkhttps://string-db.org/network/28176.CF66_2302Esterase/lipase.
pgm protein networkhttps://string-db.org/network/28176.CF66_2306Phosphoglucomutase.
CF66_2307 protein networkhttps://string-db.org/network/28176.CF66_2307Hypothetical protein.
gltA protein networkhttps://string-db.org/network/28176.CF66_2308Citrate synthase; Belongs to the citrate synthase family.
sdhC protein networkhttps://string-db.org/network/28176.CF66_2309Succinate dehydrogenase cytochrome b556 subunit.
sdhD protein networkhttps://string-db.org/network/28176.CF66_2310Succinate dehydrogenase hydrophobic membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
sdhA protein networkhttps://string-db.org/network/28176.CF66_2311Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
sdhB protein networkhttps://string-db.org/network/28176.CF66_2312Succinate dehydrogenase iron-sulfur subunit.
sucA protein networkhttps://string-db.org/network/28176.CF66_23132-oxoglutarate dehydrogenase E1 component.
sucB protein networkhttps://string-db.org/network/28176.CF66_2314Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex.
sucC protein networkhttps://string-db.org/network/28176.CF66_2315succinyl-CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represen [...]
sucD protein networkhttps://string-db.org/network/28176.CF66_2316succinyl-CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represe [...]
rnt protein networkhttps://string-db.org/network/28176.CF66_2317Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP [...]
motY protein networkhttps://string-db.org/network/28176.CF66_2318Sodium-type flagellar protein.
gloA protein networkhttps://string-db.org/network/28176.CF66_2319Lactoylglutathione lyase.
nth protein networkhttps://string-db.org/network/28176.CF66_2320Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- [...]
rnfE protein networkhttps://string-db.org/network/28176.CF66_2321Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
rnfG protein networkhttps://string-db.org/network/28176.CF66_2322Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.
rnfD protein networkhttps://string-db.org/network/28176.CF66_2323Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.
rnfC protein networkhttps://string-db.org/network/28176.CF66_2324Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin [...]
rnfB protein networkhttps://string-db.org/network/28176.CF66_2325Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin [...]
rnfA protein networkhttps://string-db.org/network/28176.CF66_2326Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
rpmF protein networkhttps://string-db.org/network/28176.CF66_232750S ribosomal protein L32.
plsX protein networkhttps://string-db.org/network/28176.CF66_2328Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but n [...]
fabH1 protein networkhttps://string-db.org/network/28176.CF66_23293-oxoacyl synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction wh [...]
fabD protein networkhttps://string-db.org/network/28176.CF66_2330Malonyl CoA-acyl carrier protein transacylase.
fabG protein networkhttps://string-db.org/network/28176.CF66_23323-oxoacyl reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosy [...]
acpP protein networkhttps://string-db.org/network/28176.CF66_2333Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
fabF protein networkhttps://string-db.org/network/28176.CF66_23343-oxoacyl synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
pabC protein networkhttps://string-db.org/network/28176.CF66_2335Aminodeoxychorismate lyase.
mltG protein networkhttps://string-db.org/network/28176.CF66_2336Periplasmic solute binding protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase [...]
tmk protein networkhttps://string-db.org/network/28176.CF66_2338Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
holB protein networkhttps://string-db.org/network/28176.CF66_2339DNA polymerase III subunit delta'.
ptsG protein networkhttps://string-db.org/network/28176.CF66_2340PTS system glucose-specific EIICB component.
gapA protein networkhttps://string-db.org/network/28176.CF66_2341Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
CF66_2342 protein networkhttps://string-db.org/network/28176.CF66_2342Hypothetical protein; Belongs to the UPF0312 family.
tig protein networkhttps://string-db.org/network/28176.CF66_2344Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs t [...]
clpX protein networkhttps://string-db.org/network/28176.CF66_2346ATP-dependent Clp protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the abs [...]
lon protein networkhttps://string-db.org/network/28176.CF66_2347Protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeosta [...]
ppiD protein networkhttps://string-db.org/network/28176.CF66_2349Peptidyl-prolyl cis-trans isomerase D.
cmk protein networkhttps://string-db.org/network/28176.CF66_2350Cytidylate kinase.
rpsA protein networkhttps://string-db.org/network/28176.CF66_235130S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
ihfB protein networkhttps://string-db.org/network/28176.CF66_2352Integration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in tran [...]
CF66_2353 protein networkhttps://string-db.org/network/28176.CF66_2353Membrane protein.
lapB protein networkhttps://string-db.org/network/28176.CF66_2354Hypothetical protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towa [...]
pyrF protein networkhttps://string-db.org/network/28176.CF66_2355Rotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily [...]
CF66_2356 protein networkhttps://string-db.org/network/28176.CF66_2356Hypothetical protein.
lolA protein networkhttps://string-db.org/network/28176.CF66_2358Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue [...]
serS protein networkhttps://string-db.org/network/28176.CF66_2359seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
pheS protein networkhttps://string-db.org/network/28176.CF66_2361phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
pheT protein networkhttps://string-db.org/network/28176.CF66_2362phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
ihfA protein networkhttps://string-db.org/network/28176.CF66_2363Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in tra [...]
rbgA protein networkhttps://string-db.org/network/28176.CF66_2364Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
sdaA protein networkhttps://string-db.org/network/28176.CF66_2365L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family.
queD protein networkhttps://string-db.org/network/28176.CF66_23676-carboxy-5,6,7,8-tetrahydropterin synthase.
pabB protein networkhttps://string-db.org/network/28176.CF66_2368Para-aminobenzoate synthase.
fumB protein networkhttps://string-db.org/network/28176.CF66_2369Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
ribA protein networkhttps://string-db.org/network/28176.CF66_2371GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family [...]
CF66_2372 protein networkhttps://string-db.org/network/28176.CF66_2372Hypothetical protein.
deaD protein networkhttps://string-db.org/network/28176.CF66_2373Cold-shock protein; Belongs to the DEAD box helicase family.
queC protein networkhttps://string-db.org/network/28176.CF66_23747-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
queE protein networkhttps://string-db.org/network/28176.CF66_2375Queosine biosynthesis; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynt [...]
aroH protein networkhttps://string-db.org/network/28176.CF66_2376Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptuloson [...]
ygaD protein networkhttps://string-db.org/network/28176.CF66_2377Multidrug export ATP-binding/permease protein.
gdhB protein networkhttps://string-db.org/network/28176.CF66_2378NAD-specific glutamate dehydrogenase.
pyrD protein networkhttps://string-db.org/network/28176.CF66_2379Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
CF66_2380 protein networkhttps://string-db.org/network/28176.CF66_2380Hypothetical protein.
fabA protein networkhttps://string-db.org/network/28176.CF66_23813-hydroxydecanoyl dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its iso [...]
tusE protein networkhttps://string-db.org/network/28176.CF66_2384Sulfurtransferase; Part of a sulfur-relay system.
folE protein networkhttps://string-db.org/network/28176.CF66_2385GTP cyclohydrolase 1.
CF66_2387 protein networkhttps://string-db.org/network/28176.CF66_2387Hypothetical protein.
CF66_2388 protein networkhttps://string-db.org/network/28176.CF66_2388Hypothetical protein.
tal protein networkhttps://string-db.org/network/28176.CF66_2390Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
tkt2 protein networkhttps://string-db.org/network/28176.CF66_2391Transketolase 2; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
thrS protein networkhttps://string-db.org/network/28176.CF66_2392threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
infC protein networkhttps://string-db.org/network/28176.CF66_2393Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enha [...]
rpmI protein networkhttps://string-db.org/network/28176.CF66_239450S ribosomal protein L35.
rplT protein networkhttps://string-db.org/network/28176.CF66_239550S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing func [...]
CF66_2396 protein networkhttps://string-db.org/network/28176.CF66_2396Hypothetical protein.
ccoN protein networkhttps://string-db.org/network/28176.CF66_2397Cytochrome c oxidase subunit 1; Belongs to the heme-copper respiratory oxidase family.
ccoO protein networkhttps://string-db.org/network/28176.CF66_2398Cytochrome c oxidase subunit.
ccoQ protein networkhttps://string-db.org/network/28176.CF66_2399Cytochrome c oxidase.
ccoP2 protein networkhttps://string-db.org/network/28176.CF66_2400Cbb3-type cytochrome c oxidase subunit; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
CF66_2401 protein networkhttps://string-db.org/network/28176.CF66_2401Hypothetical protein.
ccoI protein networkhttps://string-db.org/network/28176.CF66_2402Cytochrome c oxidase biogenesis protein.
ccoS protein networkhttps://string-db.org/network/28176.CF66_2403Cytochrome c oxidase maturation protein.
braZ protein networkhttps://string-db.org/network/28176.CF66_2404Branched-chain amino acid transport system 3 carrier protein.
CF66_2405 protein networkhttps://string-db.org/network/28176.CF66_2405Hypothetical protein.
rnb protein networkhttps://string-db.org/network/28176.CF66_2406Exoribonuclease 2; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
ydgI protein networkhttps://string-db.org/network/28176.CF66_2407Arginine/ornithine antiporter.
CF66_2408 protein networkhttps://string-db.org/network/28176.CF66_2408Acyl dehydratase.
purD protein networkhttps://string-db.org/network/28176.CF66_2409Phosphoribosylamine-glycine ligase; Belongs to the GARS family.
purH protein networkhttps://string-db.org/network/28176.CF66_2410Bifunctional purine biosynthesis protein.
asnS protein networkhttps://string-db.org/network/28176.CF66_2412asparaginyl-tRNA synthetase.
aspC protein networkhttps://string-db.org/network/28176.CF66_2413Aspartate aminotransferase.
trxB protein networkhttps://string-db.org/network/28176.CF66_2414Thioredoxin reductase.
cydD protein networkhttps://string-db.org/network/28176.CF66_2415ATP-binding/permease protein.
cydC protein networkhttps://string-db.org/network/28176.CF66_2416ATP-binding/permease protein.
rluB protein networkhttps://string-db.org/network/28176.CF66_2418Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family.
ispZ protein networkhttps://string-db.org/network/28176.CF66_2419Intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
CF66_2420 protein networkhttps://string-db.org/network/28176.CF66_2420Hypothetical protein.
serC protein networkhttps://string-db.org/network/28176.CF66_2421Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belon [...]
CF66_2422 protein networkhttps://string-db.org/network/28176.CF66_2422Hypothetical protein.
CF66_2423 protein networkhttps://string-db.org/network/28176.CF66_2423Signaling protein.
nadA protein networkhttps://string-db.org/network/28176.CF66_2424Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
CF66_2425 protein networkhttps://string-db.org/network/28176.CF66_2425Hypothetical protein.
pal protein networkhttps://string-db.org/network/28176.CF66_2426Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
tolB protein networkhttps://string-db.org/network/28176.CF66_2427Protein tolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
tolA protein networkhttps://string-db.org/network/28176.CF66_2428Protein tolA.
ompH protein networkhttps://string-db.org/network/28176.CF66_3001Porin-like protein H.
aspC-2 protein networkhttps://string-db.org/network/28176.CF66_3003Aspartate/tyrosine/aromatic aminotransferase.
pfkA protein networkhttps://string-db.org/network/28176.CF66_30056-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
CF66_3006 protein networkhttps://string-db.org/network/28176.CF66_3006Hypothetical protein.
uvrD protein networkhttps://string-db.org/network/28176.CF66_3008DNA helicase II.
priA protein networkhttps://string-db.org/network/28176.CF66_3009Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its h [...]
metL protein networkhttps://string-db.org/network/28176.CF66_3010Bifunctional aspartokinase/homoserine dehydrogenase 2; Belongs to the aspartokinase family.
pyrE protein networkhttps://string-db.org/network/28176.CF66_3011Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
gpo protein networkhttps://string-db.org/network/28176.CF66_3012Glutathione peroxidase; Belongs to the glutathione peroxidase family.
CF66_3013 protein networkhttps://string-db.org/network/28176.CF66_3013Hypothetical protein.
CF66_3014 protein networkhttps://string-db.org/network/28176.CF66_3014ABC transporter ATP binding protein; Belongs to the ABC transporter superfamily.
CF66_3015 protein networkhttps://string-db.org/network/28176.CF66_3015ABC transporter membrane protein.
CF66_3016 protein networkhttps://string-db.org/network/28176.CF66_3016ABC transporter binding protein.
luxG protein networkhttps://string-db.org/network/28176.CF66_3017Flavin reductase luxG.
luxE protein networkhttps://string-db.org/network/28176.CF66_3018Acyl protein synthetase LuxE.
luxB protein networkhttps://string-db.org/network/28176.CF66_3019Lkanal monooxygenase beta chain luxB.
luxA protein networkhttps://string-db.org/network/28176.CF66_3020Alkanal monooxygenase alpha chain luxA.
luxD protein networkhttps://string-db.org/network/28176.CF66_3021Acyl transferase luxD.
luxC protein networkhttps://string-db.org/network/28176.CF66_3022acyl-CoA reductase luxC; LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.
pyrB protein networkhttps://string-db.org/network/28176.CF66_3023Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
pyrI protein networkhttps://string-db.org/network/28176.CF66_3024Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase.
dsbD protein networkhttps://string-db.org/network/28176.CF66_3025Thiol:disulfide interchange protein.
accC protein networkhttps://string-db.org/network/28176.CF66_3026Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarbox [...]
accB protein networkhttps://string-db.org/network/28176.CF66_3027Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the c [...]
aroQ protein networkhttps://string-db.org/network/28176.CF66_30283-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
smg protein networkhttps://string-db.org/network/28176.CF66_3030Protein smg; Belongs to the Smg family.
def1 protein networkhttps://string-db.org/network/28176.CF66_3032Peptide deformylase 1; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is [...]
fmt protein networkhttps://string-db.org/network/28176.CF66_3033methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
rsmB protein networkhttps://string-db.org/network/28176.CF66_3034Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
CF66_3035 protein networkhttps://string-db.org/network/28176.CF66_3035Hypothetical protein.
fre protein networkhttps://string-db.org/network/28176.CF66_3036NAD(P)H-flavin reductase.
ubiD protein networkhttps://string-db.org/network/28176.CF66_30373-octaprenyl-4-hydroxybenzoate carboxylyase; Belongs to the UbiD family.
rho protein networkhttps://string-db.org/network/28176.CF66_3038Transcription termination factor rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
trxA protein networkhttps://string-db.org/network/28176.CF66_3039Thioredoxin; Belongs to the thioredoxin family.
rpmB protein networkhttps://string-db.org/network/28176.CF66_304050S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
rpmG protein networkhttps://string-db.org/network/28176.CF66_304150S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
CF66_3042 protein networkhttps://string-db.org/network/28176.CF66_3042Hypothetical protein.
coaD protein networkhttps://string-db.org/network/28176.CF66_3043Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD [...]
CF66_3044 protein networkhttps://string-db.org/network/28176.CF66_3044ADP-heptose-LPS heptosyltransferase II.
CF66_3045 protein networkhttps://string-db.org/network/28176.CF66_3045alpha-L-glycero-D-manno-heptose beta-1,4-glucosyltransferase.
CF66_3046 protein networkhttps://string-db.org/network/28176.CF66_3046Lipopolysaccharide heptosyltransferase I.
kdkA protein networkhttps://string-db.org/network/28176.CF66_30473-deoxy-D-manno-octulosonic acid kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the [...]
purN protein networkhttps://string-db.org/network/28176.CF66_3048Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylg [...]
purM protein networkhttps://string-db.org/network/28176.CF66_3049Phosphoribosylformylglycinamidine cycloligase.
rsmD protein networkhttps://string-db.org/network/28176.CF66_3050Ribosomal RNA small subunit methyltransferase D; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD [...]
ftsY protein networkhttps://string-db.org/network/28176.CF66_3051Cell division protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle [...]
rpoH protein networkhttps://string-db.org/network/28176.CF66_3053RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involve [...]
ubiA protein networkhttps://string-db.org/network/28176.CF66_30544-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubi [...]
hemY protein networkhttps://string-db.org/network/28176.CF66_3055Protein hemY.
hemX protein networkhttps://string-db.org/network/28176.CF66_3056uroporphyrinogen-III C-methyltransferase.
hemD protein networkhttps://string-db.org/network/28176.CF66_3057uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
hemC protein networkhttps://string-db.org/network/28176.CF66_3058Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
cyaA protein networkhttps://string-db.org/network/28176.CF66_3060Adenylate cyclase.
dapF protein networkhttps://string-db.org/network/28176.CF66_3062Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...]
CF66_3063 protein networkhttps://string-db.org/network/28176.CF66_3063Hypothetical protein.
kdsA protein networkhttps://string-db.org/network/28176.CF66_30642-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family.
glnA protein networkhttps://string-db.org/network/28176.CF66_3065Glutamine synthetase.
rpoC protein networkhttps://string-db.org/network/28176.CF66_3067DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/28176.CF66_3068DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplL protein networkhttps://string-db.org/network/28176.CF66_306950S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the ba [...]
rplJ protein networkhttps://string-db.org/network/28176.CF66_307050S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal prot [...]
rplA protein networkhttps://string-db.org/network/28176.CF66_307150S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/28176.CF66_307250S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/28176.CF66_3073Transcription antitermination protein; Participates in transcription elongation, termination and antitermination.
secE protein networkhttps://string-db.org/network/28176.CF66_3074Preprotein translocase subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs [...]
rpsF protein networkhttps://string-db.org/network/28176.CF66_400130S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
rpsR protein networkhttps://string-db.org/network/28176.CF66_400230S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosom [...]
rplI protein networkhttps://string-db.org/network/28176.CF66_400350S ribosomal protein L9; Binds to the 23S rRNA.
dnaB protein networkhttps://string-db.org/network/28176.CF66_4004Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DN [...]
alr protein networkhttps://string-db.org/network/28176.CF66_4005Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
gpmI protein networkhttps://string-db.org/network/28176.CF66_40062,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
tlpA protein networkhttps://string-db.org/network/28176.CF66_4007Methyl-accepting chemotaxis protein tlpA.
rffG protein networkhttps://string-db.org/network/28176.CF66_4008dTDP-glucose 4,6-dehydratase 2.
rfbB1 protein networkhttps://string-db.org/network/28176.CF66_4009dTDP-glucose 4,6-dehydratase.
pgi protein networkhttps://string-db.org/network/28176.CF66_4011Glucose-6-phosphate isomerase; Belongs to the GPI family.
dusA protein networkhttps://string-db.org/network/28176.CF66_4012tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. [...]
waaA protein networkhttps://string-db.org/network/28176.CF66_40133-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV( [...]
rfaF protein networkhttps://string-db.org/network/28176.CF66_4014ADP-heptose--LPS heptosyltransferase 2.
CF66_4017 protein networkhttps://string-db.org/network/28176.CF66_4017Hypothetical protein.
CF66_4019 protein networkhttps://string-db.org/network/28176.CF66_4019Polysaccharide deacetylase.
CF66_4022 protein networkhttps://string-db.org/network/28176.CF66_4022CAAX amino terminal protease.
flgT protein networkhttps://string-db.org/network/28176.CF66_4023Flagellar protein.
flgO protein networkhttps://string-db.org/network/28176.CF66_4024Flagellar protein.
rim protein networkhttps://string-db.org/network/28176.CF66_4025Ribosomal protein S12 methylthiotransferase Rim.
flgN protein networkhttps://string-db.org/network/28176.CF66_4026Flagellar biosynthesis protein.
flgA protein networkhttps://string-db.org/network/28176.CF66_4027Flagellar basal-body P-ring formation protein; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring as [...]
cheV protein networkhttps://string-db.org/network/28176.CF66_4028Chemotaxis protein cheV.
cheR protein networkhttps://string-db.org/network/28176.CF66_4029Chemotaxis protein methyltransferase.
flgB protein networkhttps://string-db.org/network/28176.CF66_4030Flagellar basal-body rod protein flgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
flgC protein networkhttps://string-db.org/network/28176.CF66_4031Flagellar basal-body rod protein flgC; Belongs to the flagella basal body rod proteins family.
flgD protein networkhttps://string-db.org/network/28176.CF66_4032Basal-body rod modification protein flgD; Required for flagellar hook formation. May act as a scaffolding protein.
flgE protein networkhttps://string-db.org/network/28176.CF66_4033Flagellar hook protein flgE.
flgF protein networkhttps://string-db.org/network/28176.CF66_4034Flagellar basal-body rod protein flgF.
flgG protein networkhttps://string-db.org/network/28176.CF66_4035Flagellar basal-body rod protein flgG; Belongs to the flagella basal body rod proteins family.
flgH protein networkhttps://string-db.org/network/28176.CF66_4036Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
flgI protein networkhttps://string-db.org/network/28176.CF66_4038Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
flgJ protein networkhttps://string-db.org/network/28176.CF66_4039Flagellar rod assembly protein/muramidase flgJ.
flgK protein networkhttps://string-db.org/network/28176.CF66_4040Flagellar hook-associated protein 1; Belongs to the flagella basal body rod proteins family.
flgL protein networkhttps://string-db.org/network/28176.CF66_4041Flagellar hook-associated protein 3.
flaA protein networkhttps://string-db.org/network/28176.CF66_4042Flagellin A; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
engD protein networkhttps://string-db.org/network/28176.CF66_4043GTP-dependent nucleic acid-binding protein engD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
pth protein networkhttps://string-db.org/network/28176.CF66_4045peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
prs protein networkhttps://string-db.org/network/28176.CF66_4046Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hy [...]
ispE protein networkhttps://string-db.org/network/28176.CF66_40474-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
lolB protein networkhttps://string-db.org/network/28176.CF66_4048Outer-membrane lipoprotein lolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
hemA protein networkhttps://string-db.org/network/28176.CF66_4049glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
prfa protein networkhttps://string-db.org/network/28176.CF66_4050Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
hemK protein networkhttps://string-db.org/network/28176.CF66_4051Protein methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the pro [...]
tmcA protein networkhttps://string-db.org/network/28176.CF66_4052tRNA(Met) cytidine acetyltransferase.
ung protein networkhttps://string-db.org/network/28176.CF66_4053uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
queA protein networkhttps://string-db.org/network/28176.CF66_4054S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ [...]
tgt protein networkhttps://string-db.org/network/28176.CF66_4055Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in [...]
yajC protein networkhttps://string-db.org/network/28176.CF66_4056Membrane protein yajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and ass [...]
secD protein networkhttps://string-db.org/network/28176.CF66_4057Protein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protei [...]
secF protein networkhttps://string-db.org/network/28176.CF66_4058Protein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protei [...]
hldD protein networkhttps://string-db.org/network/28176.CF66_4059ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the [...]
CF66_4061 protein networkhttps://string-db.org/network/28176.CF66_4061Peroxiredoxin.
dapD protein networkhttps://string-db.org/network/28176.CF66_40622,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using [...]
flaD protein networkhttps://string-db.org/network/28176.CF66_4063Flagellin D; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
ribD protein networkhttps://string-db.org/network/28176.CF66_4064Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal s [...]
ribB protein networkhttps://string-db.org/network/28176.CF66_40653,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
ribH protein networkhttps://string-db.org/network/28176.CF66_40666,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. [...]
nusB protein networkhttps://string-db.org/network/28176.CF66_4068N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of t [...]
thiL protein networkhttps://string-db.org/network/28176.CF66_4069Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thi [...]
pdxB protein networkhttps://string-db.org/network/28176.CF66_5003Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
acnB protein networkhttps://string-db.org/network/28176.CF66_5004Aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family.
pcnB protein networkhttps://string-db.org/network/28176.CF66_5005poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencin [...]
folK protein networkhttps://string-db.org/network/28176.CF66_50062-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.
panC protein networkhttps://string-db.org/network/28176.CF66_5007Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
yciK protein networkhttps://string-db.org/network/28176.CF66_5008Oxidoreductase yciK.
sohB protein networkhttps://string-db.org/network/28176.CF66_5009Protease sohB.
CF66_5011 protein networkhttps://string-db.org/network/28176.CF66_5011Hypothetical protein.
CF66_5012 protein networkhttps://string-db.org/network/28176.CF66_5012Hypothetical protein.
hrpA protein networkhttps://string-db.org/network/28176.CF66_5013ATP-dependent RNA helicase hrpA.
xthA protein networkhttps://string-db.org/network/28176.CF66_5014Exodeoxyribonuclease III.
alaS protein networkhttps://string-db.org/network/28176.CF66_5017alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
coaA protein networkhttps://string-db.org/network/28176.CF66_6001Pantothenate kinase.
tpiA protein networkhttps://string-db.org/network/28176.CF66_6002Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
efp protein networkhttps://string-db.org/network/28176.CF66_6003Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by [...]
CF66_6004 protein networkhttps://string-db.org/network/28176.CF66_6004Hypothetical protein.
galU protein networkhttps://string-db.org/network/28176.CF66_6005UTP--glucose-1-phosphate uridylyltransferase.
hslR protein networkhttps://string-db.org/network/28176.CF66_6006Heat shock protein 15; Belongs to the HSP15 family.
epsC protein networkhttps://string-db.org/network/28176.CF66_6008General secretion pathway protein C.
epsD protein networkhttps://string-db.org/network/28176.CF66_6009General secretion pathway protein D.
epsE protein networkhttps://string-db.org/network/28176.CF66_6010General secretion pathway protein E.
epsF protein networkhttps://string-db.org/network/28176.CF66_6011General secretion pathway protein F.
epsG protein networkhttps://string-db.org/network/28176.CF66_6012General secretion pathway protein G.
epsH protein networkhttps://string-db.org/network/28176.CF66_6013General secretion pathway protein H.
epsI protein networkhttps://string-db.org/network/28176.CF66_6014General secretion pathway protein I.
epsJ protein networkhttps://string-db.org/network/28176.CF66_6015General secretion pathway protein J.
epsK protein networkhttps://string-db.org/network/28176.CF66_6016General secretion pathway protein K.
epsL protein networkhttps://string-db.org/network/28176.CF66_6017General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
epsM protein networkhttps://string-db.org/network/28176.CF66_6018General secretion pathway protein M.
epsN protein networkhttps://string-db.org/network/28176.CF66_6019General secretion pathway protein N.
nudE protein networkhttps://string-db.org/network/28176.CF66_6020ADP compounds hydrolase nudE; Belongs to the Nudix hydrolase family.
nfuA protein networkhttps://string-db.org/network/28176.CF66_6021Fe/S biogenesis protein nfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S protei [...]
gmhA protein networkhttps://string-db.org/network/28176.CF66_6022Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
tusA protein networkhttps://string-db.org/network/28176.CF66_6024Sulfurtransferase TusA; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.
hemG protein networkhttps://string-db.org/network/28176.CF66_6025Protoporphyrinogen IX dehydrogenase.
glmU protein networkhttps://string-db.org/network/28176.CF66_6026Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer [...]
atpC protein networkhttps://string-db.org/network/28176.CF66_6027ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.
atpD protein networkhttps://string-db.org/network/28176.CF66_6028ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
atpG protein networkhttps://string-db.org/network/28176.CF66_6029ATP synthase gamma chain.
atpA protein networkhttps://string-db.org/network/28176.CF66_6030ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
atpH protein networkhttps://string-db.org/network/28176.CF66_6031ATP synthase subunit delta.
atpF protein networkhttps://string-db.org/network/28176.CF66_6032ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
atpE protein networkhttps://string-db.org/network/28176.CF66_6033ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramemb [...]
atpB1 protein networkhttps://string-db.org/network/28176.CF66_6034ATP synthase subunit a 1; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.
atpI protein networkhttps://string-db.org/network/28176.CF66_6035ATP synthase protein I.
parA-2 protein networkhttps://string-db.org/network/28176.CF66_6037parA protein.
rsmG protein networkhttps://string-db.org/network/28176.CF66_6038Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
mnmG protein networkhttps://string-db.org/network/28176.CF66_6040tRNA uridine 5-carboxymethylaminomethyl modification enzyme; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, [...]
CF66_6041 protein networkhttps://string-db.org/network/28176.CF66_6041Hypothetical protein.
fabF-2 protein networkhttps://string-db.org/network/28176.CF66_60423-oxoacyl-[acyl-carrier-protein] synthase 2; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
mnmE protein networkhttps://string-db.org/network/28176.CF66_6043tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
oxaA protein networkhttps://string-db.org/network/28176.CF66_6044Inner membrane protein oxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane protein [...]
CF66_6045 protein networkhttps://string-db.org/network/28176.CF66_6045Membrane insertion efficiency protein.
rnpA protein networkhttps://string-db.org/network/28176.CF66_6046Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. [...]
rpmH protein networkhttps://string-db.org/network/28176.CF66_604750S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
CF66_7001 protein networkhttps://string-db.org/network/28176.CF66_7001Hypothetical protein.
iptG protein networkhttps://string-db.org/network/28176.CF66_7002Lipopolysaccharide export system permease protein lptG.
iptF protein networkhttps://string-db.org/network/28176.CF66_7003Lipopolysaccharide export system permease protein lptF.
pepA protein networkhttps://string-db.org/network/28176.CF66_7004Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
valS protein networkhttps://string-db.org/network/28176.CF66_7005valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
iptD protein networkhttps://string-db.org/network/28176.CF66_7006LPS-assembly protein lptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
surA protein networkhttps://string-db.org/network/28176.CF66_7008Chaperone surA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, whic [...]
pdxA protein networkhttps://string-db.org/network/28176.CF66_70094-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decar [...]
rsmA protein networkhttps://string-db.org/network/28176.CF66_7011Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S part [...]
apaH protein networkhttps://string-db.org/network/28176.CF66_7012Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
CF66_7013 protein networkhttps://string-db.org/network/28176.CF66_7013Dihydrofolate reductase type 3; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
cgtA protein networkhttps://string-db.org/network/28176.CF66_7014GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of [...]
rpmA protein networkhttps://string-db.org/network/28176.CF66_701550S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
rplU protein networkhttps://string-db.org/network/28176.CF66_701650S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
ispB protein networkhttps://string-db.org/network/28176.CF66_7017Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
mdh protein networkhttps://string-db.org/network/28176.CF66_7018Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
metK protein networkhttps://string-db.org/network/28176.CF66_7019S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formati [...]
gshB protein networkhttps://string-db.org/network/28176.CF66_7020Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
ruvX protein networkhttps://string-db.org/network/28176.CF66_7021Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
CF66_7022 protein networkhttps://string-db.org/network/28176.CF66_7022Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
CF66_7023 protein networkhttps://string-db.org/network/28176.CF66_7023Hypothetical protein.
rdgB protein networkhttps://string-db.org/network/28176.CF66_7024Nucleoside 5-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucl [...]
hemN-2 protein networkhttps://string-db.org/network/28176.CF66_7025Oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is [...]
trmB protein networkhttps://string-db.org/network/28176.CF66_7026tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
mutY protein networkhttps://string-db.org/network/28176.CF66_7027A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
CF66_7028 protein networkhttps://string-db.org/network/28176.CF66_7028Fe(2+)-trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzyme [...]
plsC protein networkhttps://string-db.org/network/28176.CF66_70291-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
murA protein networkhttps://string-db.org/network/28176.CF66_7030UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
ttg2F protein networkhttps://string-db.org/network/28176.CF66_7031Toluene transport system; Belongs to the BolA/IbaG family.
rsvB protein networkhttps://string-db.org/network/28176.CF66_7032Anti sigma factor b.
mlaC protein networkhttps://string-db.org/network/28176.CF66_7033Phospholipid ABC transporter protein.
mlaD protein networkhttps://string-db.org/network/28176.CF66_7034Phospholipid ABC transporter-binding protein.
mlaE protein networkhttps://string-db.org/network/28176.CF66_7035Phospholipid ABC transporter permease protein.
mlaF protein networkhttps://string-db.org/network/28176.CF66_7036Phospholipid import ATP-binding protein.
yrbG protein networkhttps://string-db.org/network/28176.CF66_7038Inner membrane protein yrbG.
kdsD protein networkhttps://string-db.org/network/28176.CF66_7039Arabinose 5-phosphate isomerase.
kdsC protein networkhttps://string-db.org/network/28176.CF66_70403-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate [...]
lptC protein networkhttps://string-db.org/network/28176.CF66_7041Lipopolysaccharide export system protein lptC; Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Belongs to the LptC family.
lptA protein networkhttps://string-db.org/network/28176.CF66_7042Lipopolysaccharide export system protein lptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form [...]
lptB protein networkhttps://string-db.org/network/28176.CF66_7043Lipopolysaccharide export system ATP-binding protein.
pmbA protein networkhttps://string-db.org/network/28176.CF66_7045Protein pmbA.
ubiX protein networkhttps://string-db.org/network/28176.CF66_70463-polyprenyl-4-hydroxybenzoate carboxylyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase [...]
rplQ protein networkhttps://string-db.org/network/28176.CF66_704750S ribosomal protein L17.
rpoA protein networkhttps://string-db.org/network/28176.CF66_7048DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpsD protein networkhttps://string-db.org/network/28176.CF66_704930S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpsK protein networkhttps://string-db.org/network/28176.CF66_705030S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
rpsM protein networkhttps://string-db.org/network/28176.CF66_705130S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 [...]
rpmJ protein networkhttps://string-db.org/network/28176.CF66_705250S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
secY protein networkhttps://string-db.org/network/28176.CF66_7053Preprotein translocase subunit secY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at t [...]
rplO protein networkhttps://string-db.org/network/28176.CF66_705450S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
rpmD protein networkhttps://string-db.org/network/28176.CF66_705550S ribosomal protein L30.
rpsE protein networkhttps://string-db.org/network/28176.CF66_705630S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 fam [...]
rplR protein networkhttps://string-db.org/network/28176.CF66_705750S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protubera [...]
rplF protein networkhttps://string-db.org/network/28176.CF66_705850S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the t [...]
rpsH protein networkhttps://string-db.org/network/28176.CF66_705930S ribosomal protein S8.
rpsN protein networkhttps://string-db.org/network/28176.CF66_706030S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the un [...]
rplE protein networkhttps://string-db.org/network/28176.CF66_706150S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [...]
rplX protein networkhttps://string-db.org/network/28176.CF66_706250S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplN protein networkhttps://string-db.org/network/28176.CF66_706350S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rpsQ protein networkhttps://string-db.org/network/28176.CF66_706530S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rpmC protein networkhttps://string-db.org/network/28176.CF66_706650S ribosomal protein L29.
rplP protein networkhttps://string-db.org/network/28176.CF66_706750S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpsC protein networkhttps://string-db.org/network/28176.CF66_706830S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplV protein networkhttps://string-db.org/network/28176.CF66_706950S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wal [...]
rpsS protein networkhttps://string-db.org/network/28176.CF66_707030S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplB protein networkhttps://string-db.org/network/28176.CF66_707150S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rplW protein networkhttps://string-db.org/network/28176.CF66_707250S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main dock [...]
rplD protein networkhttps://string-db.org/network/28176.CF66_707350S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
rplC protein networkhttps://string-db.org/network/28176.CF66_707450S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rpsJ protein networkhttps://string-db.org/network/28176.CF66_707530S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
rlmB protein networkhttps://string-db.org/network/28176.CF66_707623S rRNA (guanosine-2'-O-)-methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
rnr protein networkhttps://string-db.org/network/28176.CF66_7077Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
motX protein networkhttps://string-db.org/network/28176.CF66_7078sSodium-type polar flagellar protein motX.
purA protein networkhttps://string-db.org/network/28176.CF66_7079Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
iaaA protein networkhttps://string-db.org/network/28176.CF66_7080Isoaspartyl peptidase.
kefB protein networkhttps://string-db.org/network/28176.CF66_7081Glutathione-regulated potassium-efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
purH-2 protein networkhttps://string-db.org/network/28176.CF66_7082Bifunctional purine biosynthesis protein.
erpA protein networkhttps://string-db.org/network/28176.CF66_7083Iron-sulfur cluster insertion protein erpA; Required for insertion of 4Fe-4S clusters for at least IspG.
pntA protein networkhttps://string-db.org/network/28176.CF66_7085NAD(P) transhydrogenase subunit alpha.
pntB protein networkhttps://string-db.org/network/28176.CF66_7087NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the [...]
coaBC protein networkhttps://string-db.org/network/28176.CF66_7088Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopan [...]
htrB protein networkhttps://string-db.org/network/28176.CF66_7089Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
gmk protein networkhttps://string-db.org/network/28176.CF66_7090Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
rpoZ protein networkhttps://string-db.org/network/28176.CF66_7091DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alp [...]
spoT protein networkhttps://string-db.org/network/28176.CF66_7092Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cell [...]
recG protein networkhttps://string-db.org/network/28176.CF66_7093ATP-dependent DNA helicase recG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwindin [...]
yocR protein networkhttps://string-db.org/network/28176.CF66_7094Sodium-dependent transporter yocR.
mnmA protein networkhttps://string-db.org/network/28176.CF66_7095tRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
hflD protein networkhttps://string-db.org/network/28176.CF66_7096High frequency lysogenization protein hflD.
purB protein networkhttps://string-db.org/network/28176.CF66_7097Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
htpX protein networkhttps://string-db.org/network/28176.CF66_7098Protease htpX; Belongs to the peptidase M48B family.
ftsN protein networkhttps://string-db.org/network/28176.CF66_7099Cell division protein.
csrA protein networkhttps://string-db.org/network/28176.CF66_7100Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid g [...]
cspV protein networkhttps://string-db.org/network/28176.CF66_7101Cold shock protein.
fieF protein networkhttps://string-db.org/network/28176.CF66_7102Cation-efflux pump; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
pyrC protein networkhttps://string-db.org/network/28176.CF66_7103Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
znuA protein networkhttps://string-db.org/network/28176.CF66_7105High-affinity zinc uptake system protein.
znuC protein networkhttps://string-db.org/network/28176.CF66_7106Zinc import ATP-binding protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superf [...]
znuB protein networkhttps://string-db.org/network/28176.CF66_7108High-affinity zinc uptake system membrane protein.
purF protein networkhttps://string-db.org/network/28176.CF66_7110Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine p [...]
cvpA protein networkhttps://string-db.org/network/28176.CF66_7111Colicin V production protein.
dedD protein networkhttps://string-db.org/network/28176.CF66_7112Protein dedD.
folC protein networkhttps://string-db.org/network/28176.CF66_7113Bifunctional protein folC; Belongs to the folylpolyglutamate synthase family.
accD1 protein networkhttps://string-db.org/network/28176.CF66_7114Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 1; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on i [...]
truA protein networkhttps://string-db.org/network/28176.CF66_7115tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
ppnK protein networkhttps://string-db.org/network/28176.CF66_9001Band 7 family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-h [...]
smpA protein networkhttps://string-db.org/network/28176.CF66_9002Small protein A.
CF66_9003 protein networkhttps://string-db.org/network/28176.CF66_9003Hypothetical protein.
ratA protein networkhttps://string-db.org/network/28176.CF66_9004Ribosome association toxin.
smpB protein networkhttps://string-db.org/network/28176.CF66_9005ssrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
CF66_9006 protein networkhttps://string-db.org/network/28176.CF66_9006Kef-type potassium channel.
agcS protein networkhttps://string-db.org/network/28176.CF66_9007Sodium/alanine symporter.
guaA protein networkhttps://string-db.org/network/28176.CF66_9008GMP synthase; Catalyzes the synthesis of GMP from XMP.
guaB protein networkhttps://string-db.org/network/28176.CF66_9009Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesi [...]
xseA protein networkhttps://string-db.org/network/28176.CF66_9010Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleo [...]
der protein networkhttps://string-db.org/network/28176.CF66_9011GTPase; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
yfgL protein networkhttps://string-db.org/network/28176.CF66_9012Lipoprotein yfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
CF66_9013 protein networkhttps://string-db.org/network/28176.CF66_9013Membrane protein.
hisS protein networkhttps://string-db.org/network/28176.CF66_9014histidyl-tRNA synthetase.
ispG protein networkhttps://string-db.org/network/28176.CF66_90154-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG fa [...]
CF66_9016 protein networkhttps://string-db.org/network/28176.CF66_9016Hypothetical protein.
rlmN protein networkhttps://string-db.org/network/28176.CF66_9017Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial [...]
ndk protein networkhttps://string-db.org/network/28176.CF66_9018Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, [...]
iscX protein networkhttps://string-db.org/network/28176.CF66_9019Protein iscX.
fdx protein networkhttps://string-db.org/network/28176.CF66_90202Fe-2S ferredoxin.
hscA protein networkhttps://string-db.org/network/28176.CF66_9021Chaperone protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
hscB protein networkhttps://string-db.org/network/28176.CF66_9022Co-chaperone protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
iscA protein networkhttps://string-db.org/network/28176.CF66_9023Iron-binding protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. [...]
iscU protein networkhttps://string-db.org/network/28176.CF66_9024nifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S cluster [...]
iscs protein networkhttps://string-db.org/network/28176.CF66_9025Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental [...]
iscR protein networkhttps://string-db.org/network/28176.CF66_9026HTH-type transcriptional regulator.
CF66_9027 protein networkhttps://string-db.org/network/28176.CF66_9027Inositol-1-monophosphatase.
clpB protein networkhttps://string-db.org/network/28176.CF66_9028Chaperone protein ClpB; Belongs to the ClpA/ClpB family.
yfiH protein networkhttps://string-db.org/network/28176.CF66_9029Laccase domain protein yfiH; Belongs to the multicopper oxidase YfiH/RL5 family.
rluD protein networkhttps://string-db.org/network/28176.CF66_9030Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
bamD protein networkhttps://string-db.org/network/28176.CF66_9031Lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
cca protein networkhttps://string-db.org/network/28176.CF66_9032Multifunctional CCA protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
eno protein networkhttps://string-db.org/network/28176.CF66_9033Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
pyrG protein networkhttps://string-db.org/network/28176.CF66_9034CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the fo [...]
relA protein networkhttps://string-db.org/network/28176.CF66_9035GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to chan [...]
acpS protein networkhttps://string-db.org/network/28176.CF66_9036Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
pdxJ protein networkhttps://string-db.org/network/28176.CF66_9037Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amin [...]
recO protein networkhttps://string-db.org/network/28176.CF66_9038DNA repair protein; Involved in DNA repair and RecF pathway recombination.
era protein networkhttps://string-db.org/network/28176.CF66_9039GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cyc [...]
rnc protein networkhttps://string-db.org/network/28176.CF66_9040Ribonuclease 3; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRN [...]
lepB protein networkhttps://string-db.org/network/28176.CF66_9041Signal peptidase I; Belongs to the peptidase S26 family.
lepA protein networkhttps://string-db.org/network/28176.CF66_9042Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon bac [...]
rseC protein networkhttps://string-db.org/network/28176.CF66_9044Sigma factor RpoE regulatory protein.
nadB protein networkhttps://string-db.org/network/28176.CF66_9045L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
CF66_9046 protein networkhttps://string-db.org/network/28176.CF66_9046Hypothetical protein.
ygfZ protein networkhttps://string-db.org/network/28176.CF66_9047tRNA-modifying protein ygfZ; Belongs to the GcvT family.
visC protein networkhttps://string-db.org/network/28176.CF66_9048Protein visC.
ubiH protein networkhttps://string-db.org/network/28176.CF66_90492-octaprenyl-6-methoxyphenol hydroxylase.
zapA protein networkhttps://string-db.org/network/28176.CF66_9050Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation [...]
ygfA protein networkhttps://string-db.org/network/28176.CF66_90515,10-methenyltetrahydrofolate synthetase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
rpiA protein networkhttps://string-db.org/network/28176.CF66_9052Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
tyrA protein networkhttps://string-db.org/network/28176.CF66_9053T-protein.
ispH protein networkhttps://string-db.org/network/28176.CF66_90544-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethyl [...]
ispA-2 protein networkhttps://string-db.org/network/28176.CF66_9055Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
ileS protein networkhttps://string-db.org/network/28176.CF66_9056isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
ribF protein networkhttps://string-db.org/network/28176.CF66_9057Riboflavin biosynthesis protein ribF; Belongs to the ribF family.
mviN protein networkhttps://string-db.org/network/28176.CF66_9058Membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
rpsT protein networkhttps://string-db.org/network/28176.CF66_905930S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
thyA protein networkhttps://string-db.org/network/28176.CF66_9060Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate ( [...]
lgt protein networkhttps://string-db.org/network/28176.CF66_9061Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
rppH protein networkhttps://string-db.org/network/28176.CF66_9062RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can [...]
mutH protein networkhttps://string-db.org/network/28176.CF66_9063DNA mismatch repair protein mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.
holD protein networkhttps://string-db.org/network/28176.CF66_9064DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuc [...]
polC protein networkhttps://string-db.org/network/28176.CF66_9065DNA polymerase III epsilon subunit.
braB protein networkhttps://string-db.org/network/28176.CF66_9068Branched-chain amino acid transport system 2 carrier protein; Component of the transport system for branched-chain amino acids.
prfB protein networkhttps://string-db.org/network/28176.CF66_9069Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
lysS protein networkhttps://string-db.org/network/28176.CF66_9070lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
CF66_9071 protein networkhttps://string-db.org/network/28176.CF66_9071Membrane protein.
pdxH protein networkhttps://string-db.org/network/28176.CF66_9073Pyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
CF66_9076 protein networkhttps://string-db.org/network/28176.CF66_9076RNA-binding protein.
murI protein networkhttps://string-db.org/network/28176.CF66_9077Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
aroC protein networkhttps://string-db.org/network/28176.CF66_9078Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
mltD protein networkhttps://string-db.org/network/28176.CF66_9079Embrane-bound lytic murein transglycosylase D.
rnhA protein networkhttps://string-db.org/network/28176.CF66_9081Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
dnaQ protein networkhttps://string-db.org/network/28176.CF66_9082DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing funct [...]
CF66_9084 protein networkhttps://string-db.org/network/28176.CF66_9084Hypothetical protein.
dsbA protein networkhttps://string-db.org/network/28176.CF66_9085Thiol:disulfide interchange protein DsbA.
fixG protein networkhttps://string-db.org/network/28176.CF66_9087NADH:ubiquinone oxidoreductase subunit I.
spoOM protein networkhttps://string-db.org/network/28176.CF66_9089Sporulation related protein spoOM.