Organism Overview: Blochmannia pennsylvanicus


 
gidA protein networkhttps://string-db.org/network/291272.BPEN_001Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s( [...]
atpB protein networkhttps://string-db.org/network/291272.BPEN_002ATP synthase, F0 sector, subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
atpE protein networkhttps://string-db.org/network/291272.BPEN_003ATP synthase, F0 sector, subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing t [...]
atpF protein networkhttps://string-db.org/network/291272.BPEN_004ATP synthase, F0 sector, subunit b; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing t [...]
atpH protein networkhttps://string-db.org/network/291272.BPEN_005ATP synthase, F1 sector, delta-subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containi [...]
atpA protein networkhttps://string-db.org/network/291272.BPEN_006ATP synthase, F1 sector, alpha-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta c [...]
atpG protein networkhttps://string-db.org/network/291272.BPEN_007ATP synthase, F1 sector, gamma-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity a [...]
atpD protein networkhttps://string-db.org/network/291272.BPEN_008ATP synthase, F1 sector, beta-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to th [...]
atpC protein networkhttps://string-db.org/network/291272.BPEN_009ATP synthase, F1 sector, epsilon-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
glmU protein networkhttps://string-db.org/network/291272.BPEN_010N-acetyl glucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domai [...]
trmE protein networkhttps://string-db.org/network/291272.BPEN_011GTPase for tRNA modification and thiophene and furan oxidation; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the w [...]
yidCD protein networkhttps://string-db.org/network/291272.BPEN_012Putative protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
rnpA protein networkhttps://string-db.org/network/291272.BPEN_013RNase P, protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The p [...]
rmpH protein networkhttps://string-db.org/network/291272.BPEN_01450S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 famil [...]
dnaN protein networkhttps://string-db.org/network/291272.BPEN_015DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadi [...]
gyrB protein networkhttps://string-db.org/network/291272.BPEN_016DNA gyrase, subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in [...]
ibpA protein networkhttps://string-db.org/network/291272.BPEN_017Heat shock protein A; Ortholog to Escherichia coli bnum: b3687; MultiFun: Cell processes 5.5.2, 5.5.6; Belongs to the small heat shock protein (HSP20) family.
BPEN_018 protein networkhttps://string-db.org/network/291272.BPEN_018Probable transmembrane protein.
glyQ protein networkhttps://string-db.org/network/291272.BPEN_019glycine-tRNA synthetase, alpha subunit; Ortholog to Escherichia coli bnum: b3560; MultiFun: Information transfer 2.3.1.
glyS protein networkhttps://string-db.org/network/291272.BPEN_020glycine-tRNA synthetase, beta subunit; Ortholog to Escherichia coli bnum: b3559; MultiFun: Information transfer 2.3.1.
sodA protein networkhttps://string-db.org/network/291272.BPEN_021Superoxide dismutase (Mn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
pitA protein networkhttps://string-db.org/network/291272.BPEN_024Low-affinity phosphate transport protein (PiT family); Ortholog to Escherichia coli bnum: b3493; MultiFun: Cell structure 6.1; Metabolism 1.8.1; Transport 4.2.A.20, 4.S.155.
ubiA protein networkhttps://string-db.org/network/291272.BPEN_0254-hydroxybenzoate octaprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ub [...]
zur protein networkhttps://string-db.org/network/291272.BPEN_026Transcriptional repressor of Zn transport system (Fur family); Ortholog to Escherichia coli bnum: b4046; MultiFun: Information transfer 2.2.2; Regulation 3.1.1, 3.1.2.3, 3.3.1; Belongs to the Fur [...]
dnaB protein networkhttps://string-db.org/network/291272.BPEN_027Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DN [...]
ssb protein networkhttps://string-db.org/network/291272.BPEN_028ssDNA-binding protein controls activity of RecBCD nuclease; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit the [...]
yjcE protein networkhttps://string-db.org/network/291272.BPEN_029Putative sodium:hydrogen antiporter (CPA1 family); Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transpo [...]
gltP protein networkhttps://string-db.org/network/291272.BPEN_030Glutamate:aspartate symporter (DAACS family); Catalyzes the proton-dependent transport of glutamate and aspartate; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) fam [...]
yjgF protein networkhttps://string-db.org/network/291272.BPEN_031Putative translation initiation inhibitor; Ortholog to Escherichia coli bnum: b4243.
argI protein networkhttps://string-db.org/network/291272.BPEN_032Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs t [...]
valS protein networkhttps://string-db.org/network/291272.BPEN_033Valine tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such error [...]
holC protein networkhttps://string-db.org/network/291272.BPEN_034DNA polymerase III, chi subunit; Ortholog to Escherichia coli bnum: b4259; MultiFun: Information transfer 2.1.1.
pepA protein networkhttps://string-db.org/network/291272.BPEN_035Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
yjgP protein networkhttps://string-db.org/network/291272.BPEN_036Putative transmembrane protein, transport; Ortholog to Escherichia coli bnum: b4261; MultiFun: Cell structure 6.1; Transport 4.
yjgQ protein networkhttps://string-db.org/network/291272.BPEN_037Putative transmembrane protein, transport; Ortholog to Escherichia coli bnum: b4262; MultiFun: Cell structure 6.1.
yidZ protein networkhttps://string-db.org/network/291272.BPEN_038Putative transcriptional regulator with periplasmic binding protein domain (LysR family); Ortholog to Escherichia coli bnum: b3711; MultiFun: Information transfer 2.2.2; Regulation 3.1.2.2, 3.1.2 [...]
BPEN_040 protein networkhttps://string-db.org/network/291272.BPEN_040Conserved hypothetical protein (NT02BF0038).
znuC protein networkhttps://string-db.org/network/291272.BPEN_041High-affinity Zn transport protein (ABC superfamily, atp_bind); Ortholog to Escherichia coli bnum: b1858; MultiFun: Metabolism 1.5.3.12; Transport 4.3.A.1.a, 4.S.191.
znuB protein networkhttps://string-db.org/network/291272.BPEN_042High-affinity Zn transport protein (ABC superfamily, membrane); Ortholog to Escherichia coli bnum: b1859; MultiFun: Cell structure 6.1; Transport 4.3.A.1.m, 4.S.191.
yhbG protein networkhttps://string-db.org/network/291272.BPEN_043Putative transport protein (ABC superfamily, atp_bind); Ortholog to Escherichia coli bnum: b3201; MultiFun: Transport 4.3.A.1.a.
yhbN protein networkhttps://string-db.org/network/291272.BPEN_044Putative transport protein (ABC superfamily, peri_bind); Ortholog to Escherichia coli bnum: b3200; MultiFun: Transport 4.3.A.1.p.
yrbK protein networkhttps://string-db.org/network/291272.BPEN_045Possible exported protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of L [...]
yrbA protein networkhttps://string-db.org/network/291272.BPEN_046Putative transcriptional regulator (BolA family); Ortholog to Escherichia coli bnum: b3190; MultiFun: Regulation 3.1.2; Belongs to the BolA/IbaG family.
murA protein networkhttps://string-db.org/network/291272.BPEN_047UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
degQ protein networkhttps://string-db.org/network/291272.BPEN_048Serine protease; Ortholog to Escherichia coli bnum: b3234; MultiFun: Metabolism 1.2.3; Belongs to the peptidase S1C family.
yhcB protein networkhttps://string-db.org/network/291272.BPEN_049Conserved hypothetical protein; Ortholog to Escherichia coli bnum: b3233.
rplM protein networkhttps://string-db.org/network/291272.BPEN_05050S ribosomal subunitprotein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early [...]
rpsI protein networkhttps://string-db.org/network/291272.BPEN_05130S ribosomal subunit protein S9; Ortholog to Escherichia coli bnum: b3230; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the universal ribosomal protein uS9 family.
yraP protein networkhttps://string-db.org/network/291272.BPEN_052Putative periplasmic protein; Ortholog to Escherichia coli bnum: b3150; MultiFun: Transport 4.9.B.
yraL protein networkhttps://string-db.org/network/291272.BPEN_053Conserved hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
rpoD protein networkhttps://string-db.org/network/291272.BPEN_057RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the pri [...]
dnaG protein networkhttps://string-db.org/network/291272.BPEN_058DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpsU protein networkhttps://string-db.org/network/291272.BPEN_05930S ribosomal subunit protein S21; Ortholog to Escherichia coli bnum: b3065; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bS21 famil [...]
gcp protein networkhttps://string-db.org/network/291272.BPEN_060Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is invo [...]
ygiH protein networkhttps://string-db.org/network/291272.BPEN_061Putative membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-ph [...]
folB protein networkhttps://string-db.org/network/291272.BPEN_062Dihydroneopterin aldolase, also has dihydroneopterin triphosphate; Ortholog to Escherichia coli bnum: b3058; MultiFun: Metabolism 1.5.3.2.
bacA protein networkhttps://string-db.org/network/291272.BPEN_063Bacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
cca protein networkhttps://string-db.org/network/291272.BPEN_064tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order [...]
hldE protein networkhttps://string-db.org/network/291272.BPEN_065ADP-heptose synthase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-te [...]
ribB protein networkhttps://string-db.org/network/291272.BPEN_0673,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
plsC protein networkhttps://string-db.org/network/291272.BPEN_0681-acyl-glycerol-3-phosphate acyltransferase; Ortholog to Escherichia coli bnum: b3018; MultiFun: Cell structure 6.1; Metabolism 1.5.4; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferas [...]
metC protein networkhttps://string-db.org/network/291272.BPEN_069Beta-cystathionase; Ortholog to Escherichia coli bnum: b3008; MultiFun: Metabolism 1.5.1.9.
cutA protein networkhttps://string-db.org/network/291272.BPEN_071Periplasmic divalent cation tolerance protein; Ortholog to Escherichia coli bnum: b4137; MultiFun: Cell processes 5.5.6; Metabolism 1.6.15.1.
groES protein networkhttps://string-db.org/network/291272.BPEN_072GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
groEL protein networkhttps://string-db.org/network/291272.BPEN_073GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
efp protein networkhttps://string-db.org/network/291272.BPEN_074Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by [...]
yjeP protein networkhttps://string-db.org/network/291272.BPEN_075Putative membrane protein; Ortholog to Escherichia coli bnum: b4159; MultiFun: Transport 4.9.B.
psd protein networkhttps://string-db.org/network/291272.BPEN_076Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
orn protein networkhttps://string-db.org/network/291272.BPEN_077Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
yjeE protein networkhttps://string-db.org/network/291272.BPEN_079Putative enzyme with nucleoside triP hydrolase domain; Ortholog to Escherichia coli bnum: b4168.
amiB protein networkhttps://string-db.org/network/291272.BPEN_080N-acetylmuramoyl-L-alanine amidase; Ortholog to Escherichia coli bnum: b4169; MultiFun: Cell processes 5.1; Cell structure 6.2; Metabolism 1.6.7.
miaA protein networkhttps://string-db.org/network/291272.BPEN_081Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, lea [...]
hfq protein networkhttps://string-db.org/network/291272.BPEN_082Host factor I; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in meta [...]
hflX protein networkhttps://string-db.org/network/291272.BPEN_083HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX [...]
hflK protein networkhttps://string-db.org/network/291272.BPEN_084HflK; HflC and HflK could encode or regulate a protease.
hflC protein networkhttps://string-db.org/network/291272.BPEN_085HflC; HflC and HflK could regulate a protease.
purA protein networkhttps://string-db.org/network/291272.BPEN_086Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
rlmB protein networkhttps://string-db.org/network/291272.BPEN_087Probable tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransfera [...]
rpsF protein networkhttps://string-db.org/network/291272.BPEN_08830S ribosomal subunit protein S6; Binds together with S18 to 16S ribosomal RNA.
rpsR protein networkhttps://string-db.org/network/291272.BPEN_08930S ribosomal subunit protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial [...]
rplI protein networkhttps://string-db.org/network/291272.BPEN_09050S ribosomal subunit protein L9; Binds to the 23S rRNA.
cysQ protein networkhttps://string-db.org/network/291272.BPEN_091CysQ; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.
ytfM protein networkhttps://string-db.org/network/291272.BPEN_092Putative outer membrane protein; Ortholog to E. coli bnum: b4220; in-frame premature UAG termination codon is located within the ytfM sequence, and a -1 frameshift would be required for synthesis [...]
ytfN protein networkhttps://string-db.org/network/291272.BPEN_093Putative exported protein; Ortholog to Escherichia coli bnum: b4221.
ppa protein networkhttps://string-db.org/network/291272.BPEN_094Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
ispB protein networkhttps://string-db.org/network/291272.BPEN_095Octaprenyl-diphosphate synthase; Ortholog to Escherichia coli bnum: b3187; MultiFun: Metabolism 1.5.3.19; Belongs to the FPP/GGPP synthase family.
rplU protein networkhttps://string-db.org/network/291272.BPEN_09650S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
rpmA protein networkhttps://string-db.org/network/291272.BPEN_09750S ribosomal subunit protein L27; Ortholog to Escherichia coli bnum: b3185; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL27 famil [...]
cgtA protein networkhttps://string-db.org/network/291272.BPEN_098Putative GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Play [...]
greA protein networkhttps://string-db.org/network/291272.BPEN_099Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a [...]
rrmJ protein networkhttps://string-db.org/network/291272.BPEN_100Ribosomal RNA large subunit (23S) methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal sub [...]
hflB protein networkhttps://string-db.org/network/291272.BPEN_101HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA A [...]
folP protein networkhttps://string-db.org/network/291272.BPEN_1027,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immedi [...]
mrsA protein networkhttps://string-db.org/network/291272.BPEN_103PGM/PMM-family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
secG protein networkhttps://string-db.org/network/291272.BPEN_104Preprotein translocase, membrane component; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
nusA protein networkhttps://string-db.org/network/291272.BPEN_107L factor; Participates in both transcription termination and antitermination.
infB protein networkhttps://string-db.org/network/291272.BPEN_108Translation initiation factor IF2-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
rbfA protein networkhttps://string-db.org/network/291272.BPEN_10930S ribosome-binding factor; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but [...]
truB protein networkhttps://string-db.org/network/291272.BPEN_110tRNA pseudouridine 5S synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
rpsO protein networkhttps://string-db.org/network/291272.BPEN_11130S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridg [...]
pnp protein networkhttps://string-db.org/network/291272.BPEN_112Polynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
deaD protein networkhttps://string-db.org/network/291272.BPEN_113Cold-shock DeaD box ATP-dependent RNA helicase; Ortholog to Escherichia coli bnum: b3162; MultiFun: Information transfer 2.2.3; Belongs to the DEAD box helicase family.
holD protein networkhttps://string-db.org/network/291272.BPEN_114DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonu [...]
thrA protein networkhttps://string-db.org/network/291272.BPEN_115Bifunctional; ortholog to Escherichia coli bnum: b0002; MultiFun: Metabolism 1.5.1.21, 1.5.1.8; homoserine dehydrogenase I, threonine sensitive; In the C-terminal section; belongs to the homoseri [...]
thrB protein networkhttps://string-db.org/network/291272.BPEN_116Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
thrC protein networkhttps://string-db.org/network/291272.BPEN_117Threonine synthase; Ortholog to Escherichia coli bnum: b0004; MultiFun: Metabolism 1.5.1.8.
dnaK protein networkhttps://string-db.org/network/291272.BPEN_118DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
dnaJ protein networkhttps://string-db.org/network/291272.BPEN_119DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-i [...]
rpsT protein networkhttps://string-db.org/network/291272.BPEN_12030S ribosomal subunit protein S20; Binds directly to 16S ribosomal RNA.
ribF protein networkhttps://string-db.org/network/291272.BPEN_121Bifunctional: flavokinase; Ortholog to Escherichia coli bnum: b0025; MultiFun: Metabolism 1.5.3.9; Belongs to the ribF family.
ileS protein networkhttps://string-db.org/network/291272.BPEN_122isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
lspA protein networkhttps://string-db.org/network/291272.BPEN_123Prolipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
ispH protein networkhttps://string-db.org/network/291272.BPEN_1241-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, 4Fe-4S protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosph [...]
dapB protein networkhttps://string-db.org/network/291272.BPEN_125Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
carA protein networkhttps://string-db.org/network/291272.BPEN_126Carbamoyl-phosphate synthase, small chain; Ortholog to Escherichia coli bnum: b0032; MultiFun: Metabolism 1.5.1.3, 1.5.2.2; Belongs to the CarA family.
carB protein networkhttps://string-db.org/network/291272.BPEN_127Carbamoyl-phosphate synthase, large chain; Ortholog to Escherichia coli bnum: b0033; MultiFun: Metabolism 1.5.1.3, 1.5.2.2.
folA protein networkhttps://string-db.org/network/291272.BPEN_128Dihydrofolate reductase type I; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
apaH protein networkhttps://string-db.org/network/291272.BPEN_129Bis(5'-nucleosyl)-tetraphosphatase; Ortholog to Escherichia coli bnum: b0049; MultiFun: Metabolism 1.7.33.
ksgA protein networkhttps://string-db.org/network/291272.BPEN_130Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a c [...]
pdxA protein networkhttps://string-db.org/network/291272.BPEN_1314-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decar [...]
surA protein networkhttps://string-db.org/network/291272.BPEN_132Peptidyl-prolyl cis-trans isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of th [...]
imp protein networkhttps://string-db.org/network/291272.BPEN_133Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
leuD protein networkhttps://string-db.org/network/291272.BPEN_1343-isopropylmalate dehydratase subunit 1; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD ty [...]
leuC protein networkhttps://string-db.org/network/291272.BPEN_1353-isopropylmalate dehydratase subunit 2; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
leuB protein networkhttps://string-db.org/network/291272.BPEN_1363-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-met [...]
leuA protein networkhttps://string-db.org/network/291272.BPEN_1372-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isoprop [...]
mraW protein networkhttps://string-db.org/network/291272.BPEN_138S-adenosyl-dependent methyl transferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
ftsL protein networkhttps://string-db.org/network/291272.BPEN_139Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, whi [...]
ftsI protein networkhttps://string-db.org/network/291272.BPEN_140Division-specific transpeptidase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
murE protein networkhttps://string-db.org/network/291272.BPEN_141UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG [...]
murF protein networkhttps://string-db.org/network/291272.BPEN_142D-alanine:D-alanine-adding enzyme; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF [...]
mraY protein networkhttps://string-db.org/network/291272.BPEN_143phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY su [...]
murD protein networkhttps://string-db.org/network/291272.BPEN_144UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDE [...]
ftsW protein networkhttps://string-db.org/network/291272.BPEN_145Cell division protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
murG protein networkhttps://string-db.org/network/291272.BPEN_146Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
murC protein networkhttps://string-db.org/network/291272.BPEN_147UDP-N-acetyl-muramate:alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
ftsQ protein networkhttps://string-db.org/network/291272.BPEN_148Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, whi [...]
ftsA protein networkhttps://string-db.org/network/291272.BPEN_149Cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
ftsZ protein networkhttps://string-db.org/network/291272.BPEN_150Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing a [...]
lpxC protein networkhttps://string-db.org/network/291272.BPEN_151UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed st [...]
secA protein networkhttps://string-db.org/network/291272.BPEN_152Preprotein translocase, ATPase secretion component; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrol [...]
coaE protein networkhttps://string-db.org/network/291272.BPEN_153Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
dksA protein networkhttps://string-db.org/network/291272.BPEN_154Dosage-dependent dnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulat [...]
folK protein networkhttps://string-db.org/network/291272.BPEN_1552-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Ortholog to Escherichia coli bnum: b0142; MultiFun: Metabolism 1.5.3.2.
lpdA protein networkhttps://string-db.org/network/291272.BPEN_156Dihydrolipoyl dehydrogenase; Ortholog to Escherichia coli bnum: b0116; MultiFun: Metabolism 1.1.1.20, 1.1.3.5, 1.3.3, 1.3.4, 1.3.6, 1.3.7, 1.7.17, 1.7.21.
aceF protein networkhttps://string-db.org/network/291272.BPEN_157Pyruvate dehydrogenase, dihydrolipoyltransacetylase subunit (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
aceE protein networkhttps://string-db.org/network/291272.BPEN_158Pyruvate dehydrogenase, decarboxylase subunit (E1), thiamin-binding; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO( [...]
mrcB protein networkhttps://string-db.org/network/291272.BPEN_159Penicillin-binding protein 1b: glycosyl transferase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycos [...]
yadR protein networkhttps://string-db.org/network/291272.BPEN_160Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG.
pyrG protein networkhttps://string-db.org/network/291272.BPEN_161CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the [...]
eno protein networkhttps://string-db.org/network/291272.BPEN_162Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
cysJ protein networkhttps://string-db.org/network/291272.BPEN_163Sulfite reductase, alpha subunit (flavoprotein); Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities requir [...]
cysI protein networkhttps://string-db.org/network/291272.BPEN_164Sulfite reductase, beta subunit, NADPH-dependent hemoprotein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several acti [...]
cysH protein networkhttps://string-db.org/network/291272.BPEN_1653'-phosphoadenosine 5'-phosphosulfate (PAPS) reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
cysG protein networkhttps://string-db.org/network/291272.BPEN_166Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form [...]
cysD protein networkhttps://string-db.org/network/291272.BPEN_167ATP-sulfurylase, subunit 2; Ortholog to Escherichia coli bnum: b2752; MultiFun: Metabolism 1.8.2; ATP:sulfate adenylyltransferase.
cysN protein networkhttps://string-db.org/network/291272.BPEN_168ATP-sulfurylase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. Cy [...]
cysC protein networkhttps://string-db.org/network/291272.BPEN_169Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate.
ygbQ protein networkhttps://string-db.org/network/291272.BPEN_170Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, whi [...]
ispD protein networkhttps://string-db.org/network/291272.BPEN_1714-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to the I [...]
ispF protein networkhttps://string-db.org/network/291272.BPEN_1722C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid [...]
nlpD protein networkhttps://string-db.org/network/291272.BPEN_173Lipoprotein NlpD precursor; Ortholog to Escherichia coli bnum: b2742; MultiFun: Cell structure 6.1.
alaS protein networkhttps://string-db.org/network/291272.BPEN_174alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
csrA protein networkhttps://string-db.org/network/291272.BPEN_175Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid g [...]
ffh protein networkhttps://string-db.org/network/291272.BPEN_1784.5S-RNP protein; GTP-binding export factor; part of signal recognition particle with 4.5 RNA; ortholog to Escherichia coli bnum: b2610; MultiFun: Transport 4.3.A.5; Transport 4.S.160.
rpsP protein networkhttps://string-db.org/network/291272.BPEN_17930S ribosomal subunit protein S16; Ortholog to Escherichia coli bnum: b2609; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bS16 famil [...]
rimM protein networkhttps://string-db.org/network/291272.BPEN_18016S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Ess [...]
trmD protein networkhttps://string-db.org/network/291272.BPEN_181tRNA(guanine-N1)methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rplS protein networkhttps://string-db.org/network/291272.BPEN_18250S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
aroF protein networkhttps://string-db.org/network/291272.BPEN_183Phospho-2-dehydro-3-deoxyheptonate aldolase, tyr-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptuloson [...]
tyrA protein networkhttps://string-db.org/network/291272.BPEN_184Chorismate mutase T; Bifunctional; ortholog to Escherichia coli bnum: b2600; MultiFun: Metabolism 1.5.1.13, 1.5.1.14; prephenate dehydrogenase.
pheA protein networkhttps://string-db.org/network/291272.BPEN_185Chorismate mutase P; Bifunctional; ortholog to Escherichia coli bnum: b2599; MultiFun: Metabolism 1.5.1.13, 1.5.1.14; prephenate dehydratase.
yfiO protein networkhttps://string-db.org/network/291272.BPEN_186Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the [...]
rluD protein networkhttps://string-db.org/network/291272.BPEN_187Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
clpB protein networkhttps://string-db.org/network/291272.BPEN_188ATP-dependent protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to t [...]
murB protein networkhttps://string-db.org/network/291272.BPEN_189UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
birA protein networkhttps://string-db.org/network/291272.BPEN_190biotin-[acetylCoA carboxylase] holoenzyme synthetase; Bifunctional; ortholog to Escherichia coli bnum: b3973; MultiFun: Information transfer 2.2.2; Metabolism 1.5.3.1; Regulation 3.1.2.3, 3.3.1; [...]
coaA protein networkhttps://string-db.org/network/291272.BPEN_191Pantothenate kinase; Ortholog to Escherichia coli bnum: b3974; MultiFun: Metabolism 1.5.3.5.
bfr protein networkhttps://string-db.org/network/291272.BPEN_196Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation wit [...]
rpsJ protein networkhttps://string-db.org/network/291272.BPEN_19730S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
rplC protein networkhttps://string-db.org/network/291272.BPEN_19850S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rplD protein networkhttps://string-db.org/network/291272.BPEN_19950S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. [...]
rplW protein networkhttps://string-db.org/network/291272.BPEN_20050S ribosomal subunit protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the m [...]
rplB protein networkhttps://string-db.org/network/291272.BPEN_20150S ribosomal subunit protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond format [...]
rpsS protein networkhttps://string-db.org/network/291272.BPEN_20230S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplV protein networkhttps://string-db.org/network/291272.BPEN_20350S ribosomal subunit protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stag [...]
rpsC protein networkhttps://string-db.org/network/291272.BPEN_20430S ribosomal subunit protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 fami [...]
rplP protein networkhttps://string-db.org/network/291272.BPEN_20550S ribosomal subunit protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpmC protein networkhttps://string-db.org/network/291272.BPEN_20650S ribosomal subunit protein L29; Ortholog to Escherichia coli bnum: b3312; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the universal ribosomal protein uL29 famil [...]
rpsQ protein networkhttps://string-db.org/network/291272.BPEN_20730S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rplN protein networkhttps://string-db.org/network/291272.BPEN_20850S ribosomal subunit protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rplX protein networkhttps://string-db.org/network/291272.BPEN_20950S ribosomal subunit protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rplE protein networkhttps://string-db.org/network/291272.BPEN_21050S ribosomal subunit protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central prot [...]
rpsN protein networkhttps://string-db.org/network/291272.BPEN_21130S ribosomal subunit protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs t [...]
rpsH protein networkhttps://string-db.org/network/291272.BPEN_21230S ribosomal subunit protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Bel [...]
rplF protein networkhttps://string-db.org/network/291272.BPEN_21350S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and ne [...]
rplR protein networkhttps://string-db.org/network/291272.BPEN_21450S ribosomal subunit protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central p [...]
rpsE protein networkhttps://string-db.org/network/291272.BPEN_21530S ribosomal subunit protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
rplO protein networkhttps://string-db.org/network/291272.BPEN_21750S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
secY protein networkhttps://string-db.org/network/291272.BPEN_218Preprotein translocase, membrane component; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral ga [...]
rmpJ protein networkhttps://string-db.org/network/291272.BPEN_21950S ribosomal subunit protein L36; Ortholog to Escherichia coli bnum: b3299; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL36 famil [...]
rpsM protein networkhttps://string-db.org/network/291272.BPEN_22030S ribosomal subunit protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and pr [...]
rpsK protein networkhttps://string-db.org/network/291272.BPEN_22130S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosom [...]
rpsD protein networkhttps://string-db.org/network/291272.BPEN_22230S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpoA protein networkhttps://string-db.org/network/291272.BPEN_223RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplQ protein networkhttps://string-db.org/network/291272.BPEN_22450S ribosomal subunit protein L17; Ortholog to Escherichia coli bnum: b3294; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8.
fmt protein networkhttps://string-db.org/network/291272.BPEN_225methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
def protein networkhttps://string-db.org/network/291272.BPEN_226Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine i [...]
yrdC protein networkhttps://string-db.org/network/291272.BPEN_227Putative RNA-binding protein with unique protein fold, with YrdC/RibB domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codo [...]
aroE protein networkhttps://string-db.org/network/291272.BPEN_228Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshi [...]
gloB protein networkhttps://string-db.org/network/291272.BPEN_230Probable hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
rnhA protein networkhttps://string-db.org/network/291272.BPEN_231Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
dnaQ protein networkhttps://string-db.org/network/291272.BPEN_232DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing func [...]
gmhA protein networkhttps://string-db.org/network/291272.BPEN_233Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
ahpC protein networkhttps://string-db.org/network/291272.BPEN_235Alkyl hydroperoxide reductase C22 protein; Ortholog to Escherichia coli bnum: b0605; MultiFun: Cell processes 5.6.2.
tgt protein networkhttps://string-db.org/network/291272.BPEN_236tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in t [...]
yajC protein networkhttps://string-db.org/network/291272.BPEN_237Preprotein translocase, auxillary membrane component; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of p [...]
secD protein networkhttps://string-db.org/network/291272.BPEN_238Preprotein translocase, auxillary membrane component; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF [...]
secF protein networkhttps://string-db.org/network/291272.BPEN_239Preprotein translocase, auxillary membrane component; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF [...]
ribD protein networkhttps://string-db.org/network/291272.BPEN_240Pyrimidine deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal se [...]
ribH protein networkhttps://string-db.org/network/291272.BPEN_2416,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. [...]
nusB protein networkhttps://string-db.org/network/291272.BPEN_242L factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) op [...]
pgpA protein networkhttps://string-db.org/network/291272.BPEN_243Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
dxs protein networkhttps://string-db.org/network/291272.BPEN_2441-deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP) [...]
ispA protein networkhttps://string-db.org/network/291272.BPEN_245Geranyltranstransferase; Ortholog to Escherichia coli bnum: b0421; MultiFun: Metabolism 1.5.3.19; Belongs to the FPP/GGPP synthase family.
thiI protein networkhttps://string-db.org/network/291272.BPEN_246Sulfur transfer protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the tra [...]
yajR protein networkhttps://string-db.org/network/291272.BPEN_247Putative transport protein (MFS family); Ortholog to Escherichia coli bnum: b0427; MultiFun: Cell processes 5.6.4; Cell structure 6.1; Transport 4.2.A.1,4.S.49.
cyoE protein networkhttps://string-db.org/network/291272.BPEN_248Protohaeme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
cyoD protein networkhttps://string-db.org/network/291272.BPEN_249Cytochrome o ubiquinol oxidase, subunit IV; Ortholog to Escherichia coli bnum: b0429; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2.
cyoC protein networkhttps://string-db.org/network/291272.BPEN_250Cytochrome o ubiquinol oxidase, subunit III; Ortholog to Escherichia coli bnum: b0430; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82.
cyoB protein networkhttps://string-db.org/network/291272.BPEN_251Cytochrome o ubiquinol oxidase, subunit I; Ortholog to Escherichia coli bnum: b0431; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82; Belongs to the heme-copper r [...]
cyoA protein networkhttps://string-db.org/network/291272.BPEN_252Cytochrome o ubiquinol oxidase, subunit II; Ortholog to Escherichia coli bnum: b0432; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82.
clpP protein networkhttps://string-db.org/network/291272.BPEN_253ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degrada [...]
clpX protein networkhttps://string-db.org/network/291272.BPEN_254ATP-dependent Clp protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the abs [...]
yggX protein networkhttps://string-db.org/network/291272.BPEN_255Protein involved in oxidative damage control; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in b [...]
mutY protein networkhttps://string-db.org/network/291272.BPEN_256Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.
yqgF protein networkhttps://string-db.org/network/291272.BPEN_257Putative endonuclease involved in recombination; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.
yqgE protein networkhttps://string-db.org/network/291272.BPEN_258Putative transcriptional regulator; Ortholog to Escherichia coli bnum: b2948; Belongs to the UPF0301 (AlgH) family.
metK protein networkhttps://string-db.org/network/291272.BPEN_259S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet forma [...]
speB protein networkhttps://string-db.org/network/291272.BPEN_260Agmatinase; Ortholog to Escherichia coli bnum: b2937; MultiFun: Metabolism 1.7.14; Belongs to the arginase family.
pgk protein networkhttps://string-db.org/network/291272.BPEN_261Phosphoglycerate kinase; Ortholog to Escherichia coli bnum: b2926; MultiFun: Metabolism 1.1.1.23, 1.3.1, 1.7.8; Belongs to the phosphoglycerate kinase family.
fbaA protein networkhttps://string-db.org/network/291272.BPEN_262Fructose 1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphos [...]
rpiA protein networkhttps://string-db.org/network/291272.BPEN_263Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
ygfA protein networkhttps://string-db.org/network/291272.BPEN_264Putative ligase; Ortholog to Escherichia coli bnum: b2912; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
ygfE protein networkhttps://string-db.org/network/291272.BPEN_265Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the forma [...]
ubiH protein networkhttps://string-db.org/network/291272.BPEN_2662-octaprenyl-6-methoxyphenol hydroxylase; Ortholog to Escherichia coli bnum: b2907; MultiFun: Metabolism 1.3.6, 1.5.3.11.
visC protein networkhttps://string-db.org/network/291272.BPEN_267Putative monooxygenase, FAD/NAD(P)-binding domain; Ortholog to Escherichia coli bnum: b2906.
ygfZ protein networkhttps://string-db.org/network/291272.BPEN_268Putative aminomethyltransferase; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that [...]
prfB protein networkhttps://string-db.org/network/291272.BPEN_269Peptide chain release factor 2 (RF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
lysS protein networkhttps://string-db.org/network/291272.BPEN_270lysyl-tRNA synthetase; Ortholog to Escherichia coli bnum: b2890; MultiFun: Information transfer 2.3.1; Belongs to the class-II aminoacyl-tRNA synthetase family.
lysA protein networkhttps://string-db.org/network/291272.BPEN_271Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
ygdP protein networkhttps://string-db.org/network/291272.BPEN_272Nucleotide hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can sti [...]
lgt protein networkhttps://string-db.org/network/291272.BPEN_273Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
recC protein networkhttps://string-db.org/network/291272.BPEN_274Exonuclease V, gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidi [...]
recD protein networkhttps://string-db.org/network/291272.BPEN_275Exonuclease V, alpha chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidi [...]
recB protein networkhttps://string-db.org/network/291272.BPEN_276Exonuclease V; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional hel [...]
dapD protein networkhttps://string-db.org/network/291272.BPEN_2772,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Ortholog to Escherichia coli bnum: b0166; MultiFun: Metabolism 1.5.1.7; Belongs to the transferase hexapeptide repeat family.
map protein networkhttps://string-db.org/network/291272.BPEN_278Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharg [...]
rpsB protein networkhttps://string-db.org/network/291272.BPEN_27930S ribosomal subunit protein S2; Ortholog to Escherichia coli bnum: b0169; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the universal ribosomal protein uS2 family.
tsf protein networkhttps://string-db.org/network/291272.BPEN_280Protein chain elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysi [...]
pyrH protein networkhttps://string-db.org/network/291272.BPEN_281Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
frr protein networkhttps://string-db.org/network/291272.BPEN_282Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
dxr protein networkhttps://string-db.org/network/291272.BPEN_2831-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).
uppS protein networkhttps://string-db.org/network/291272.BPEN_284Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,3 [...]
cdsA protein networkhttps://string-db.org/network/291272.BPEN_285Phosphatidate cytidylyltransferase; Ortholog to Escherichia coli bnum: b0175; MultiFun: Cell structure 6.1; Metabolism 1.6.1; Belongs to the CDS family.
ecfE protein networkhttps://string-db.org/network/291272.BPEN_286Putative membrane protein; Ortholog to Escherichia coli bnum: b0176; MultiFun: Cell processes 5.5; Cell structure 6.1; Regulation 3.1.3.4.
yaeT protein networkhttps://string-db.org/network/291272.BPEN_287Outer membrane protein precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, wi [...]
hlpA protein networkhttps://string-db.org/network/291272.BPEN_288Histone-like protein; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the perip [...]
lpxD protein networkhttps://string-db.org/network/291272.BPEN_289UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved [...]
fabZ protein networkhttps://string-db.org/network/291272.BPEN_290(3R)-hydroxymyristol acyl carrier protein dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and [...]
lpxA protein networkhttps://string-db.org/network/291272.BPEN_291UDP-N-acetylglucosamine acetyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
lpxB protein networkhttps://string-db.org/network/291272.BPEN_292lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid t [...]
rnhB protein networkhttps://string-db.org/network/291272.BPEN_293Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
dnaE protein networkhttps://string-db.org/network/291272.BPEN_294DNA polymerase III, alpha chain; Ortholog to Escherichia coli bnum: b0184; MultiFun: Information transfer 2.1.1.
accA protein networkhttps://string-db.org/network/291272.BPEN_295acetylCoA carboxylase, carboxytransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carri [...]
tilS protein networkhttps://string-db.org/network/291272.BPEN_296tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is [...]
proS protein networkhttps://string-db.org/network/291272.BPEN_297prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
gmhB protein networkhttps://string-db.org/network/291272.BPEN_298D,D-heptose 1,7-bisphosphate phosphatase; Ortholog to Escherichia coli bnum: b0200; MultiFun: Metabolism 1.6.3.2.
accC protein networkhttps://string-db.org/network/291272.BPEN_299Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier [...]
accB protein networkhttps://string-db.org/network/291272.BPEN_300acetylCoA carboxylase, BCCP subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and the [...]
aroQ protein networkhttps://string-db.org/network/291272.BPEN_3013-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
mreB protein networkhttps://string-db.org/network/291272.BPEN_302Rod shape-determining protein; Ortholog to Escherichia coli bnum: b3251; MultiFun: Cell processes 5.1; Cell processes 5.6.4.
mreC protein networkhttps://string-db.org/network/291272.BPEN_303Rod shape-determining protein; Involved in formation and maintenance of cell shape.
mreD protein networkhttps://string-db.org/network/291272.BPEN_304Rod shape-determining protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.
tldD protein networkhttps://string-db.org/network/291272.BPEN_305TldD; Putative enzyme for maturation of Microcin B17 and degradation of CcdA with winged helix domain; ortholog to Escherichia coli bnum: b3244; MultiFun: Cell processes 5.1; Information transfer [...]
pmbA protein networkhttps://string-db.org/network/291272.BPEN_306PmbA; Putative enzyme for maturation of Microcin B17 and degradation of CcdA; ortholog to Escherichia coli bnum: b4235; MultiFun: Cell processes 5.1, 5.6.3; Information transfer 2.3.5.
lon protein networkhttps://string-db.org/network/291272.BPEN_307DNA-binding ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. R [...]
apt protein networkhttps://string-db.org/network/291272.BPEN_308Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
dnaX protein networkhttps://string-db.org/network/291272.BPEN_309DNA polymerase III, tau and gamma subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' [...]
adk protein networkhttps://string-db.org/network/291272.BPEN_310Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
lpxH protein networkhttps://string-db.org/network/291272.BPEN_311UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water [...]
cysS protein networkhttps://string-db.org/network/291272.BPEN_312cysteinyl-tRNA synthetase; Ortholog to Escherichia coli bnum: b0526; MultiFun: Information transfer 2.3.1; Belongs to the class-I aminoacyl-tRNA synthetase family.
folD protein networkhttps://string-db.org/network/291272.BPEN_3135,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate [...]
ytfF protein networkhttps://string-db.org/network/291272.BPEN_315Putative cationic amino acid transport protein; Ortholog to Escherichia coli bnum: b4210; MultiFun: Transport 4, 4.S.12.
mrdB protein networkhttps://string-db.org/network/291272.BPEN_316Rod shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
mrdA protein networkhttps://string-db.org/network/291272.BPEN_317Cell elongation-specific transpeptidase of penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
ybeB protein networkhttps://string-db.org/network/291272.BPEN_318Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 3 [...]
holA protein networkhttps://string-db.org/network/291272.BPEN_319DNA polymerase III, delta subunit; Ortholog to Escherichia coli bnum: b0640; MultiFun: Information transfer 2.1.1.
rlpB protein networkhttps://string-db.org/network/291272.BPEN_320Rare lipoprotein B precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS [...]
leuS protein networkhttps://string-db.org/network/291272.BPEN_321leucyl-tRNA synthetase; Ortholog to Escherichia coli bnum: b0642; MultiFun: Information transfer 2.3.1; Belongs to the class-I aminoacyl-tRNA synthetase family.
lnt protein networkhttps://string-db.org/network/291272.BPEN_322Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrol [...]
ybeX protein networkhttps://string-db.org/network/291272.BPEN_323Putative integral membrane protein with CBS regulatory domain; Ortholog to Escherichia coli bnum: b0658; MultiFun: Cell structure 6.1.
ybeY protein networkhttps://string-db.org/network/291272.BPEN_324Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
phoL protein networkhttps://string-db.org/network/291272.BPEN_325Putative ATP-binding protein in pho regulon; Ortholog to Escherichia coli bnum: b0660; MultiFun: Transport 4.9.B.
ubiF protein networkhttps://string-db.org/network/291272.BPEN_3262-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol oxygenase; Ortholog to E. coli bnum: b0662; in-frame premature UAA termination codon is located within the ubiF sequence, and a +1 frameshift would [...]
nagA protein networkhttps://string-db.org/network/291272.BPEN_330N-acetylglucosamine-6-phosphate deacetylase; Ortholog to Escherichia coli bnum: b0677; MultiFun: Metabolism 1.7.12.
nagB protein networkhttps://string-db.org/network/291272.BPEN_331Glucosamine-6-phosphate isomerase; Ortholog to Escherichia coli bnum: b0678; MultiFun: Metabolism 1.7.12.
glnS protein networkhttps://string-db.org/network/291272.BPEN_332glutaminyl-tRNA synthetase; Ortholog to Escherichia coli bnum: b0680; MultiFun: Information transfer 2.3.1.
fldA protein networkhttps://string-db.org/network/291272.BPEN_333Flavodoxin 1; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
ybfF protein networkhttps://string-db.org/network/291272.BPEN_334Putative enzyme with alpha/beta-Hydrolase domain; Ortholog to Escherichia coli bnum: b0686.
pgm protein networkhttps://string-db.org/network/291272.BPEN_335Phosphoglucomutase; Ortholog to Escherichia coli bnum: b0688; MultiFun: Metabolism 1.1.1,1.7.9.
sdhC protein networkhttps://string-db.org/network/291272.BPEN_337Succinate dehydrogenase cytochrome b-556 subunit; Ortholog to Escherichia coli bnum: b0721; MultiFun: Cell structure 6.1; Metabolism 1.3.4, 1.3.6, 1.4.1, 1.4.3, 1.6.15.1.
sdhD protein networkhttps://string-db.org/network/291272.BPEN_338Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
sdhA protein networkhttps://string-db.org/network/291272.BPEN_339Succinate dehydrogenase catalytic and flavoprotein subunit; Ortholog to Escherichia coli bnum: b0723; MultiFun: Metabolism 1.3.4, 1.3.6, 1.4.1; Belongs to the FAD-dependent oxidoreductase 2 famil [...]
sdhB protein networkhttps://string-db.org/network/291272.BPEN_340Succinate dehydrogenase iron-sulfur protein; Ortholog to Escherichia coli bnum: b0724; MultiFun: Metabolism 1.3.4, 1.3.6, 1.4.1.
sucA protein networkhttps://string-db.org/network/291272.BPEN_3412-oxoglutarate dehydrogenase E1 component; Ortholog to Escherichia coli bnum: b0726; MultiFun: Metabolism 1.3.4.
sucB protein networkhttps://string-db.org/network/291272.BPEN_342Dihydrolipoamide succinyltransferase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl [...]
sucC protein networkhttps://string-db.org/network/291272.BPEN_343succinyl-CoA synthetase, beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus repre [...]
sucD protein networkhttps://string-db.org/network/291272.BPEN_344succinyl-CoA synthetase, alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus repr [...]
tolQ protein networkhttps://string-db.org/network/291272.BPEN_345TolQ; Inner membrane protein required for outer membrane integrity, uptake of group A colicins and phage DNA; ortholog to Escherichia coli bnum: b0737; MultiFun: Cell structure 6.1.
tolR protein networkhttps://string-db.org/network/291272.BPEN_346TolR; Role in outer membrane integrity, uptake of group A colicins (TonB-independent), and phage DNA; ortholog to Escherichia coli bnum: b0738; MultiFun: Cell structure 6.1.
tolA protein networkhttps://string-db.org/network/291272.BPEN_347TolA; Required for outer membrane integrity, uptake of group A colicins, role in translocation of filamenous phage DNA to cytoplasm, role in surface expression of O-antigen; ortholog to Escherich [...]
tolB protein networkhttps://string-db.org/network/291272.BPEN_348TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediar [...]
pal protein networkhttps://string-db.org/network/291272.BPEN_349Pal; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
ybgF protein networkhttps://string-db.org/network/291272.BPEN_350Putative periplasmic protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
ybhE protein networkhttps://string-db.org/network/291272.BPEN_351Putative isomerase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate.
gpmA protein networkhttps://string-db.org/network/291272.BPEN_352Phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
ybhL protein networkhttps://string-db.org/network/291272.BPEN_353Putative transport protein; Ortholog to Escherichia coli bnum: b0786; MultiFun: Cell structure 6.1; Transport 4; Belongs to the BI1 family.
ychF protein networkhttps://string-db.org/network/291272.BPEN_354Putative GTP-binding protein with nucleoside triP hydrolase domain; Ortholog to Escherichia coli bnum: b1203.
pth protein networkhttps://string-db.org/network/291272.BPEN_355peptidyl-tRNA hydrolase; Ortholog to Escherichia coli bnum: b1204; MultiFun: Information transfer 2.3.1.
prsA protein networkhttps://string-db.org/network/291272.BPEN_356Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to [...]
ispE protein networkhttps://string-db.org/network/291272.BPEN_3574-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. I [...]
lolB protein networkhttps://string-db.org/network/291272.BPEN_358Outer membrane lipoprotein precursor; Ortholog to Escherichia coli bnum: b1209; MultiFun: Cell structure 6.1.
prfA protein networkhttps://string-db.org/network/291272.BPEN_359Peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
hemK protein networkhttps://string-db.org/network/291272.BPEN_360N5-glutamine methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to th [...]
kdsA protein networkhttps://string-db.org/network/291272.BPEN_3613-deoxy-D-manno-octulosonic acid 8-P synthetase; Ortholog to Escherichia coli bnum: b1215; MultiFun: Cell structure 6.1, 6.2, 6.3, 6.7; Metabolism 1.6.5; Belongs to the KdsA family.
thrS protein networkhttps://string-db.org/network/291272.BPEN_362threonyl-tRNA synthetase; Ortholog to Escherichia coli bnum: b1719; MultiFun: Information transfer 2.3.1.
infC protein networkhttps://string-db.org/network/291272.BPEN_363Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enha [...]
rpmI protein networkhttps://string-db.org/network/291272.BPEN_36450S ribosomal subunit protein L35; Ortholog to Escherichia coli bnum: b1717; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL35 famil [...]
rplT protein networkhttps://string-db.org/network/291272.BPEN_36550S ribosomal subunit protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesiz [...]
pheS protein networkhttps://string-db.org/network/291272.BPEN_366Phenylalanine tRNA synthetase, alpha-subunit; Ortholog to Escherichia coli bnum: b1714; MultiFun: Information transfer 2.3.1; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA sy [...]
pheT protein networkhttps://string-db.org/network/291272.BPEN_367Phenylalanine tRNA synthetase, beta-subunit; Ortholog to Escherichia coli bnum: b1713; MultiFun: Information transfer 2.3.1; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type [...]
lplA protein networkhttps://string-db.org/network/291272.BPEN_368Lipoate-protein ligase A; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dep [...]
sufA protein networkhttps://string-db.org/network/291272.BPEN_369Fe-S cluster assembly protein; Ortholog to Escherichia coli bnum: b1684; MultiFun: Metabolism 1.7.19; Belongs to the HesB/IscA family.
sufB protein networkhttps://string-db.org/network/291272.BPEN_370Putative transport protein associated with Fe-S cluster assembly; Ortholog to Escherichia coli bnum: b1683; MultiFun: Information transfer 2.3.4.
sufC protein networkhttps://string-db.org/network/291272.BPEN_371Putative transport protein associated with Fe-S cluster assembly (ABC superfamily, atp_bind); Ortholog to Escherichia coli bnum: b1682; MultiFun: Transport 4.3.A.1.a.
sufD protein networkhttps://string-db.org/network/291272.BPEN_372SufD; Required for stability of iron-sulfur component of FhuF; ortholog to Escherichia coli bnum: b1681; MultiFun: Metabolism 1.7.19.
sufS protein networkhttps://string-db.org/network/291272.BPEN_373Selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomo [...]
sufE protein networkhttps://string-db.org/network/291272.BPEN_374SufE; Ortholog to Escherichia coli bnum: b1679; MultiFun: Regulation 3.1.3.
lpp protein networkhttps://string-db.org/network/291272.BPEN_375Murein lipoprotein; Ortholog to Escherichia coli bnum: b1677; MultiFun: Cell structure 6.1, 6.2; Metabolism 1.6.7.
ribE protein networkhttps://string-db.org/network/291272.BPEN_377Riboflavin synthase, alpha chain; Ortholog to Escherichia coli bnum: b1662; MultiFun: Metabolism 1.5.3.9.
ydhD protein networkhttps://string-db.org/network/291272.BPEN_378Conserved protein with thioredoxin-like domain; Ortholog to Escherichia coli bnum: b1654; Belongs to the glutaredoxin family. Monothiol subfamily.
rnt protein networkhttps://string-db.org/network/291272.BPEN_379Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP [...]
slyA protein networkhttps://string-db.org/network/291272.BPEN_380Transcriptional activator for hemolysin (MarR family); Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.
pdxH protein networkhttps://string-db.org/network/291272.BPEN_381Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
tyrS protein networkhttps://string-db.org/network/291272.BPEN_382tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
nth protein networkhttps://string-db.org/network/291272.BPEN_383Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- [...]
fumC protein networkhttps://string-db.org/network/291272.BPEN_384Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily [...]
eaeH protein networkhttps://string-db.org/network/291272.BPEN_385Putative adhesin; Ortholog to Escherichia coli bnum: b0297; MultiFun: Cell structure 6.1.
ubiX protein networkhttps://string-db.org/network/291272.BPEN_3863-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylas [...]
kdsB protein networkhttps://string-db.org/network/291272.BPEN_3873-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
ycaR protein networkhttps://string-db.org/network/291272.BPEN_388Conserved hypothetical protein; Ortholog to Escherichia coli bnum: b0917; Belongs to the UPF0434 family.
lpxK protein networkhttps://string-db.org/network/291272.BPEN_389Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis [...]
msbA protein networkhttps://string-db.org/network/291272.BPEN_390Lipid transport protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner [...]
rpsA protein networkhttps://string-db.org/network/291272.BPEN_39130S ribosomal subunit protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
cmk protein networkhttps://string-db.org/network/291272.BPEN_392Cytidine monophosphate (CMP) kinase; Ortholog to Escherichia coli bnum: b0910; MultiFun: Metabolism 1.5.2.4, 1.7.33.
aroA protein networkhttps://string-db.org/network/291272.BPEN_3933-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
serC protein networkhttps://string-db.org/network/291272.BPEN_3943-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phos [...]
serS protein networkhttps://string-db.org/network/291272.BPEN_395seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
lolA protein networkhttps://string-db.org/network/291272.BPEN_396LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an as [...]
ftsK protein networkhttps://string-db.org/network/291272.BPEN_397Cell division protein; Ortholog to Escherichia coli bnum: b0890; MultiFun: Cell processes 5.1, 5.8; Cell structure 6.1; Transport 4.9.A.16; Belongs to the FtsK/SpoIIIE/SftA family.
trxB protein networkhttps://string-db.org/network/291272.BPEN_398Thioredoxin reductase; Ortholog to Escherichia coli bnum: b0888; MultiFun: Metabolism 1.7.1.
infA protein networkhttps://string-db.org/network/291272.BPEN_399Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
oprC protein networkhttps://string-db.org/network/291272.BPEN_400OprC; Outer membrane protein.
yqeI protein networkhttps://string-db.org/network/291272.BPEN_401Cholera toxin transcriptional activator; Ortholog to Escherichia coli bnum: b2847.
emtA protein networkhttps://string-db.org/network/291272.BPEN_402Membrane-bound lytic murein transglycosylase E; Ortholog to Escherichia coli bnum: b1193; MultiFun: Cell structure 6.1, 6.2; Metabolism 1.6.7.
mntR protein networkhttps://string-db.org/network/291272.BPEN_403Transcriptional regulator of mntH, Mn(2+) responsive; Ortholog to Escherichia coli bnum: b0817; MultiFun: Regulation 3.1.2, 3.3.1.
trmU protein networkhttps://string-db.org/network/291272.BPEN_404tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of [...]
purB protein networkhttps://string-db.org/network/291272.BPEN_405Adenylosuccinate lyase; Ortholog to Escherichia coli bnum: b1131; MultiFun: Metabolism 1.5.2.1; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
lolE protein networkhttps://string-db.org/network/291272.BPEN_406Transport protein of outer membrane lipoproteins (ABC superfamily, membrane); Ortholog to Escherichia coli bnum: b1118; MultiFun: Cell structure 6.1; Transport 4.3.A.1.m, 4.S.106.
lolD protein networkhttps://string-db.org/network/291272.BPEN_407Transport protein of outer membrane lipoproteins (ABC superfamily, atp_bind); Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoprotei [...]
lolC protein networkhttps://string-db.org/network/291272.BPEN_408Transport protein of outer membrane lipoproteins (ABC superfamily, membrane); Ortholog to Escherichia coli bnum: b1116; MultiFun: Cell structure 6.1; Transport 4.3.A.1.m, 4.S.106.
ycfM protein networkhttps://string-db.org/network/291272.BPEN_409Putative fibronectin-binding protein; Ortholog to Escherichia coli bnum: b1105.
ycfF protein networkhttps://string-db.org/network/291272.BPEN_410Putative protein kinase C inhibitor; Ortholog to Escherichia coli bnum: b1103; MultiFun: Information transfer 2.3.
ycfH protein networkhttps://string-db.org/network/291272.BPEN_411Putative metallo-dependent hydrolase; Ortholog to Escherichia coli bnum: b1100.
holB protein networkhttps://string-db.org/network/291272.BPEN_412DNA polymerase III, delta prime subunit; Ortholog to Escherichia coli bnum: b1099; MultiFun: Information transfer 2.1.1.
tmk protein networkhttps://string-db.org/network/291272.BPEN_413Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
pabC protein networkhttps://string-db.org/network/291272.BPEN_4144-amino-4-deoxychorismate lyase; Ortholog to Escherichia coli bnum: b1096; MultiFun: Metabolism 1.5.3.2.
acpP protein networkhttps://string-db.org/network/291272.BPEN_415Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
fabG protein networkhttps://string-db.org/network/291272.BPEN_4163-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cy [...]
fabD protein networkhttps://string-db.org/network/291272.BPEN_417Malonyl CoA-acyl carrier protein transacylase; Ortholog to Escherichia coli bnum: b1092; MultiFun: Metabolism 1.5.4.
fabH protein networkhttps://string-db.org/network/291272.BPEN_4183-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first [...]
plsX protein networkhttps://string-db.org/network/291272.BPEN_419Fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty a [...]
rpmF protein networkhttps://string-db.org/network/291272.BPEN_42050S ribosomal subunit protein L32; Ortholog to Escherichia coli bnum: b1089; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL32 famil [...]
rluC protein networkhttps://string-db.org/network/291272.BPEN_421Ribosomal large subunit (23S) pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
rne protein networkhttps://string-db.org/network/291272.BPEN_422Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation [...]
lpxL protein networkhttps://string-db.org/network/291272.BPEN_423Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
ybiS protein networkhttps://string-db.org/network/291272.BPEN_424Putative exported protein; Ortholog to E. coli bnum: b0819; in-frame premature UAG termination codon is located within the ybiS sequence, and a +1 frameshift would be required for synthesis of yb [...]
pgsA protein networkhttps://string-db.org/network/291272.BPEN_427Phosphotidylglycerophosphate synthetase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
yccK protein networkhttps://string-db.org/network/291272.BPEN_430Putative sulfite reductase; Part of a sulfur-relay system.
yccV protein networkhttps://string-db.org/network/291272.BPEN_431Conserved hypothetical protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.
fabA protein networkhttps://string-db.org/network/291272.BPEN_432D-3-hydroxydecanoyl-(acyl carrier-protein); Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and [...]
asnS protein networkhttps://string-db.org/network/291272.BPEN_433asparaginyl-tRNA synthetase; Ortholog to Escherichia coli bnum: b0930; MultiFun: Information transfer 2.3.1.
aspC protein networkhttps://string-db.org/network/291272.BPEN_434Aspartate aminotransferase; Ortholog to Escherichia coli bnum: b0928; MultiFun: Metabolism 1.1.3, 1.5.1.5.
ycbL protein networkhttps://string-db.org/network/291272.BPEN_435Putative enzyme with metallo-hydrolase/oxidoreductase domain; Ortholog to Escherichia coli bnum: b0927.
fabI protein networkhttps://string-db.org/network/291272.BPEN_436Enoyl-[acyl-carrier-protein] reductase (NADH); Ortholog to Escherichia coli bnum: b1288; MultiFun: Metabolism 1.5.4.
ribA protein networkhttps://string-db.org/network/291272.BPEN_437GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
trpE protein networkhttps://string-db.org/network/291272.BPEN_438Anthranilate synthase component I; Ortholog to Escherichia coli bnum: b1264; MultiFun: Metabolism 1.5.1.15.
trpG protein networkhttps://string-db.org/network/291272.BPEN_439Anthranilate synthase component II: glutamine amidotransferase; Ortholog to Escherichia coli bnum: b1263; MultiFun: Metabolism 1.5.1.15.
trpD protein networkhttps://string-db.org/network/291272.BPEN_440Anthranilate synthase component II: anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yie [...]
trpC protein networkhttps://string-db.org/network/291272.BPEN_441Indole-3-glycerolphosphate synthetase; Bifunctional; ortholog to Escherichia coli bnum: b1262; MultiFun: Metabolism 1.5.1.15; N-(5-phosphoribosyl)anthranilate isomerase; Belongs to the TrpC famil [...]
trpB protein networkhttps://string-db.org/network/291272.BPEN_442Tryptophan synthase, beta protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpA protein networkhttps://string-db.org/network/291272.BPEN_443Tryptophan synthase, alpha protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
yciC protein networkhttps://string-db.org/network/291272.BPEN_444Putative membrane protein, transport; Ortholog to Escherichia coli bnum: b1255; MultiFun: Cell structure 6.1.
tonB protein networkhttps://string-db.org/network/291272.BPEN_445Energy transducer; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act [...]
cls protein networkhttps://string-db.org/network/291272.BPEN_446Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
tdk protein networkhttps://string-db.org/network/291272.BPEN_447Thymidine kinase; Ortholog to Escherichia coli bnum: b1238; MultiFun: Metabolism 1.7.33.
hns protein networkhttps://string-db.org/network/291272.BPEN_448DNA-binding protein HLP-II (HU, BH2, HD, NS); Ortholog to Escherichia coli bnum: b1237; MultiFun: Cell processes 5.3; Cell structure 6.4; Information transfer 2.2.2, 2.3.7; Regulation 3.1.2; Belo [...]
xthA protein networkhttps://string-db.org/network/291272.BPEN_449Exonuclease III; Ortholog to Escherichia coli bnum: b1749; MultiFun: Cell processes 5.6.1; Information transfer 2.1.5; Metabolism 1.2.2.
sppA protein networkhttps://string-db.org/network/291272.BPEN_450Protease IV; Signal peptide peptidase; ortholog to Escherichia coli bnum: b1766; MultiFun: Metabolism 1.2.3.
gapA protein networkhttps://string-db.org/network/291272.BPEN_451Glyceraldehyde 3-phosphate dehydrogenase A; Ortholog to Escherichia coli bnum: b1779; MultiFun: Metabolism 1.1.1.23, 1.3.1, 1.5.3.6, 1.7.8; Belongs to the glyceraldehyde-3-phosphate dehydrogenase [...]
dsbB protein networkhttps://string-db.org/network/291272.BPEN_452Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
minC protein networkhttps://string-db.org/network/291272.BPEN_453MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature [...]
minD protein networkhttps://string-db.org/network/291272.BPEN_454MinD; Cell division inhibitor; septum site determining protein; ortholog to Escherichia coli bnum: b1175; MultiFun: Cell processes 5.1; Cell structure 6.1.
minE protein networkhttps://string-db.org/network/291272.BPEN_455Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures c [...]
yeaZ protein networkhttps://string-db.org/network/291272.BPEN_456Putative glycoprotein endopeptidase, actin-like ATPase domain; Ortholog to Escherichia coli bnum: b1807; MultiFun: Metabolism 1.2.3.
pabB protein networkhttps://string-db.org/network/291272.BPEN_457Component of p-aminobenzoate synthase multienzyme complex; ortholog to Escherichia coli bnum: b1812; MultiFun: Metabolism 1.5.3.2.
yoaE protein networkhttps://string-db.org/network/291272.BPEN_458Putative transmembrane protein; Ortholog to Escherichia coli bnum: b1816; MultiFun: Cell structure 6.1.
manX protein networkhttps://string-db.org/network/291272.BPEN_459PTS family enzyme IIA/enzyme IIB, mannose-specific; Ortholog to Escherichia coli bnum: b1817; MultiFun: Metabolism 1.1.1; Transport 4.4.A.6, 4.S.116.
manY protein networkhttps://string-db.org/network/291272.BPEN_460PTS family enzyme IIC, mannose-specific; Ortholog to Escherichia coli bnum: b1818; MultiFun: Cell structure 6.1; Metabolism 1.1.1; Transport 4.4.A.6, 4.S.116.
manZ protein networkhttps://string-db.org/network/291272.BPEN_461PTS family enzyme IID, mannose-specific; Ortholog to Escherichia coli bnum: b1819; MultiFun: Cell structure 6.1; Metabolism 1.1.1; Transport 4.4.A.6, 4.S.116.
cspC protein networkhttps://string-db.org/network/291272.BPEN_462Cold shock-like protein; Ortholog to Escherichia coli bnum: b1823; MultiFun: Cell processes 5.5.2; Information transfer 2.2.2; Regulation 3.1.2.2.
htpX protein networkhttps://string-db.org/network/291272.BPEN_463Heat shock protein; Integral membrane protein; ortholog to Escherichia coli bnum: b1829; MultiFun: Cell processes 5.5.2; Cell structure 6.1.
zwf protein networkhttps://string-db.org/network/291272.BPEN_464Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
pykA protein networkhttps://string-db.org/network/291272.BPEN_465Pyruvate kinase A; Ortholog to Escherichia coli bnum: b1854; MultiFun: Metabolism 1.1.1.23, 1.3.1, 1.3.5, 1.3.7; Belongs to the pyruvate kinase family.
yebA protein networkhttps://string-db.org/network/291272.BPEN_466Conserved protein with LysM domain; Ortholog to Escherichia coli bnum: b1856.
aspS protein networkhttps://string-db.org/network/291272.BPEN_467aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor [...]
argS protein networkhttps://string-db.org/network/291272.BPEN_468arginyl-tRNA synthetase; Ortholog to Escherichia coli bnum: b1876; MultiFun: Information transfer 2.3.1.
mviN protein networkhttps://string-db.org/network/291272.BPEN_469Putative virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
yceL protein networkhttps://string-db.org/network/291272.BPEN_470Putative membrane transporter (MFS family); Ortholog to Escherichia coli bnum: b1065; MultiFun: Cell processes 5.6.4; Cell structure 6.1; Transport 4.2.A.1, 4.S.126.
gutQ protein networkhttps://string-db.org/network/291272.BPEN_474Putative phosphosugar binding protein; Ortholog to Escherichia coli bnum: b2708; MultiFun: Cell structure 6.7; Regulation 3.1.4.
yeeX protein networkhttps://string-db.org/network/291272.BPEN_475Conserved hypothetical protein; Ortholog to Escherichia coli bnum: b2007; Belongs to the UPF0265 family.
sbcB protein networkhttps://string-db.org/network/291272.BPEN_476Ortholog to Escherichia coli bnum: b2011; MultiFun: Information transfer 2.1.4, 2.1.5; Metabolism 1.2.2.
hisG protein networkhttps://string-db.org/network/291272.BPEN_477ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate [...]
hisD protein networkhttps://string-db.org/network/291272.BPEN_478L-histidinal:NAD+ dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
hisC protein networkhttps://string-db.org/network/291272.BPEN_479Histidinol-phosphate aminotransferase; Ortholog to Escherichia coli bnum: b2021; MultiFun: Metabolism 1.5.1.16; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Hist [...]
hisB protein networkhttps://string-db.org/network/291272.BPEN_480Histidinol-phosphatase; Bifunctional; ortholog to Escherichia coli bnum: b2022; MultiFun: Metabolism 1.5.1.16; imidazoleglycerol-phosphate dehydratase; In the N-terminal section; belongs to the h [...]
hisH protein networkhttps://string-db.org/network/291272.BPEN_481Glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as pa [...]
hisA protein networkhttps://string-db.org/network/291272.BPEN_482Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide; Ortholog to Escherichia coli bnum: b2024; MultiFun: Metabolism 1.5.1.16.
hisF protein networkhttps://string-db.org/network/291272.BPEN_483Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and [...]
hisI protein networkhttps://string-db.org/network/291272.BPEN_484phosphoribosyl-AMP cyclohydrolase; Bifunctional; ortholog to Escherichia coli bnum: b2026; MultiFun: Metabolism 1.5.1.16; phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to [...]
gnd protein networkhttps://string-db.org/network/291272.BPEN_4856-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
metG protein networkhttps://string-db.org/network/291272.BPEN_486methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
folE protein networkhttps://string-db.org/network/291272.BPEN_487GTP cyclohydrolase I; Ortholog to Escherichia coli bnum: b2153; MultiFun: Metabolism 1.5.3.2.
rplY protein networkhttps://string-db.org/network/291272.BPEN_48850S ribosomal subunit protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein [...]
ddlA protein networkhttps://string-db.org/network/291272.BPEN_490D-alanine:D-alanine ligase A; Cell wall formation.
omp protein networkhttps://string-db.org/network/291272.BPEN_491Outer membrane protein; Ortholog to Escherichia coli bnum: b2215; MultiFun: Cell structure 6.1; Transport 4.1.B.1, 4.S.92.
gyrA protein networkhttps://string-db.org/network/291272.BPEN_492DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in [...]
ubiG protein networkhttps://string-db.org/network/291272.BPEN_4933-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG [...]
nrdA protein networkhttps://string-db.org/network/291272.BPEN_494Ribonucleoside diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotid [...]
nrdB protein networkhttps://string-db.org/network/291272.BPEN_495Ribonucleoside-diphosphate reductase 1, beta subunit; Ortholog to Escherichia coli bnum: b2235; MultiFun: Metabolism 1.7.15, 1.7.33.
yfaE protein networkhttps://string-db.org/network/291272.BPEN_496Conserved hypothetical protein with 2Fe-2S ferredoxin-like domain; Ortholog to Escherichia coli bnum: b2236.
nuoN protein networkhttps://string-db.org/network/291272.BPEN_497NADH dehydrogenase I chain N, membrane subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor f [...]
nuoM protein networkhttps://string-db.org/network/291272.BPEN_498NADH dehydrogenase I chain M, membrane subunit; Ortholog to Escherichia coli bnum: b2277; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.3.7, 1.4.1; Transport 4.3.D.1, 4.S.130.
nuoL protein networkhttps://string-db.org/network/291272.BPEN_499NADH dehydrogenase I chain L, membrane subunit; Ortholog to Escherichia coli bnum: b2278; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.3.7, 1.4.1; Transport 4.3.D.1, 4.S.130.
nuoK protein networkhttps://string-db.org/network/291272.BPEN_500NADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoJ protein networkhttps://string-db.org/network/291272.BPEN_501NADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation [...]
nuoI protein networkhttps://string-db.org/network/291272.BPEN_502NADH dehydrogenase I chain I, 2Fe-2S ferredoxin-related; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron a [...]
nuoH protein networkhttps://string-db.org/network/291272.BPEN_503NADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoG protein networkhttps://string-db.org/network/291272.BPEN_504NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation [...]
nuoF protein networkhttps://string-db.org/network/291272.BPEN_505NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
nuoE protein networkhttps://string-db.org/network/291272.BPEN_506NADH dehydrogenase I chain E; Ortholog to Escherichia coli bnum: b2285; MultiFun: Metabolism 1.3.6; Metabolism 1.3.7, 1.4.1; Transport 4.3.D.1, 4.S.130.
nuoCD protein networkhttps://string-db.org/network/291272.BPEN_507NADH dehydrogenase I chain C, D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme i [...]
nuoB protein networkhttps://string-db.org/network/291272.BPEN_508NADH dehydrogenase I chain B, binds FeS cluster N2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron accept [...]
nuoA protein networkhttps://string-db.org/network/291272.BPEN_509NADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
folC protein networkhttps://string-db.org/network/291272.BPEN_510Folylpolyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate [...]
accD protein networkhttps://string-db.org/network/291272.BPEN_511acetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and [...]
truA protein networkhttps://string-db.org/network/291272.BPEN_512tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
pdxB protein networkhttps://string-db.org/network/291272.BPEN_513Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
fabB protein networkhttps://string-db.org/network/291272.BPEN_5143-oxoacyl-[acyl-carrier-protein] synthase I; Ortholog to Escherichia coli bnum: b2323; MultiFun: Metabolism 1.5.4; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
yfcB protein networkhttps://string-db.org/network/291272.BPEN_515N5-glutamine methyltransferase, modifies ribosomal protein L3; Ortholog to Escherichia coli bnum: b2330; MultiFun: Information transfer 2.3.2, 2.3.3; Belongs to the protein N5-glutamine methyltra [...]
aroC protein networkhttps://string-db.org/network/291272.BPEN_516Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
mntH protein networkhttps://string-db.org/network/291272.BPEN_518Manganese/divalent cation transport protein (NRAMP family); H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
nupC protein networkhttps://string-db.org/network/291272.BPEN_519Nucleoside transport protein (NUP family); Ortholog to Escherichia coli bnum: b2393; MultiFun: Cell structure 6.1; Metabolism 1.7.33; Transport 4.2.A.41, 4.S.146.
gltX protein networkhttps://string-db.org/network/291272.BPEN_521Glutamate tRNA synthetase, catalytic subunit; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred [...]
ligA protein networkhttps://string-db.org/network/291272.BPEN_524DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy sourc [...]
cysK protein networkhttps://string-db.org/network/291272.BPEN_525Cysteine synthase A; Ortholog to Escherichia coli bnum: b2414; MultiFun: Metabolism 1.5.1.12; Belongs to the cysteine synthase/cystathionine beta- synthase family.
ptsH protein networkhttps://string-db.org/network/291272.BPEN_526PTS family Hpr protein, phosphohistidinoprotein-hexose phosphotransferase; Ortholog to Escherichia coli bnum: b2415; MultiFun: Metabolism 1.1.1; Transport 4.8.A.8, 4.S.173.
ptsI protein networkhttps://string-db.org/network/291272.BPEN_527PTS family enzyme I and Hpr components, PEP-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). Th [...]
cysA protein networkhttps://string-db.org/network/291272.BPEN_528Sulfate permease A protein, chromate resistance (ABC superfamily, atp_bind); Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to [...]
cysW protein networkhttps://string-db.org/network/291272.BPEN_529Thiosulfate permease W protein (ABC superfamily, membrane); Ortholog to Escherichia coli bnum: b2423; MultiFun: Cell structure 6.1; Metabolism 1.8.2; Transport 4.3.A.1.m, 4.S.178.
cysU protein networkhttps://string-db.org/network/291272.BPEN_530Thiosulfate transport protein (ABC superfamily, membrane); Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent tran [...]
cysP protein networkhttps://string-db.org/network/291272.BPEN_531Thiosulfate transport protein (ABC superfamily, peri_bind); Ortholog to Escherichia coli bnum: b2425; MultiFun: Metabolism 1.8.2; Transport 4.3.A.1.p, 4.S.178.
talA protein networkhttps://string-db.org/network/291272.BPEN_532Ortholog to Escherichia coli bnum: b2464; MultiFun: Metabolism 1.7.3.
tktA protein networkhttps://string-db.org/network/291272.BPEN_533Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
dapE protein networkhttps://string-db.org/network/291272.BPEN_534Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in [...]
BPEN_535 protein networkhttps://string-db.org/network/291272.BPEN_535Conserved hypothetical protein (NT02BF0496).
dapA protein networkhttps://string-db.org/network/291272.BPEN_536Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
bcp protein networkhttps://string-db.org/network/291272.BPEN_537Bacterioferritin comigratory protein; Ortholog to Escherichia coli bnum: b2480; MultiFun: Cell processes 5.6.2.
upp protein networkhttps://string-db.org/network/291272.BPEN_538Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
BPEN_539 protein networkhttps://string-db.org/network/291272.BPEN_539Conserved hypothetical protein.
ureG protein networkhttps://string-db.org/network/291272.BPEN_540Putative urease accessory protein G; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
ureF protein networkhttps://string-db.org/network/291272.BPEN_541Putative urease accessory protein F; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
ureC protein networkhttps://string-db.org/network/291272.BPEN_542Putative urease structural subunit C (alpha); Ortholog to Escherichia coli bnum: ECs1324; MultiFun: Metabolism1.1.4.4; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subuni [...]
ureB protein networkhttps://string-db.org/network/291272.BPEN_543Putative urease structural subunit B (beta); Ortholog to Escherichia coli bnum: ECs1323; MultiFun: Metabolism1.1.4.4; Belongs to the urease beta subunit family.
ureA protein networkhttps://string-db.org/network/291272.BPEN_544Putative urease structural subunit A (gamma); Ortholog to Escherichia coli bnum: ECs1322; MultiFun: Metabolism1.1.4.4; Belongs to the urease gamma subunit family.
ureD protein networkhttps://string-db.org/network/291272.BPEN_545Putative urease accessory protein D; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
guaA protein networkhttps://string-db.org/network/291272.BPEN_546GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
guaB protein networkhttps://string-db.org/network/291272.BPEN_547Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesi [...]
mqo protein networkhttps://string-db.org/network/291272.BPEN_548Probable malate:quinone oxidoreductase; Ortholog to Escherichia coli bnum: b2210; MultiFun: Metabolism 1.3.4; malate dehydrogenase.
engA protein networkhttps://string-db.org/network/291272.BPEN_549Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (De [...]
hisS protein networkhttps://string-db.org/network/291272.BPEN_550histidyl-tRNA synthetase; Ortholog to Escherichia coli bnum: b2514; MultiFun: Information transfer 2.3.1.
ispG protein networkhttps://string-db.org/network/291272.BPEN_5511-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG [...]
yfgB protein networkhttps://string-db.org/network/291272.BPEN_552Putative pyruvate formate lyase activating enzyme 2; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a cru [...]
ndk protein networkhttps://string-db.org/network/291272.BPEN_553Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, [...]
nifS protein networkhttps://string-db.org/network/291272.BPEN_554Putative L-cysteine desulfurase; Ortholog to Escherichia coli bnum: b2530; MultiFun: Information transfer 2.3.3.
suhB protein networkhttps://string-db.org/network/291272.BPEN_555Putative myo-inositol-1(or 4)-monophosphatase; Ortholog to Escherichia coli bnum: b2533; MultiFun: Information transfer 2.2.2; Regulation 3.1.3.2; Belongs to the inositol monophosphatase superfam [...]
glyA protein networkhttps://string-db.org/network/291272.BPEN_556Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
tadA protein networkhttps://string-db.org/network/291272.BPEN_557tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
acpS protein networkhttps://string-db.org/network/291272.BPEN_558Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
pdxJ protein networkhttps://string-db.org/network/291272.BPEN_559Putative pyridoxal phosphate biosynthetic protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl [...]
rnc protein networkhttps://string-db.org/network/291272.BPEN_560RNase III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, a [...]
lepB protein networkhttps://string-db.org/network/291272.BPEN_561Signal peptidase I; Ortholog to Escherichia coli bnum: b2568; MultiFun: Cell structure 6.1; Information transfer 2.3.5; Transport 4.S.160; Belongs to the peptidase S26 family.
lepA protein networkhttps://string-db.org/network/291272.BPEN_562GTP-binding elongation factor; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one [...]
ung protein networkhttps://string-db.org/network/291272.BPEN_563uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
grpE protein networkhttps://string-db.org/network/291272.BPEN_564Heat shock protein 24; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is th [...]
yfjB protein networkhttps://string-db.org/network/291272.BPEN_565Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically t [...]
smpA protein networkhttps://string-db.org/network/291272.BPEN_566Small membrane protein A; Ortholog to Escherichia coli bnum: b2617; MultiFun: Cell structure 6.1.
yfjG protein networkhttps://string-db.org/network/291272.BPEN_567Conserved hypothetical protein; Ortholog to Escherichia coli bnum: b2619.
smpB protein networkhttps://string-db.org/network/291272.BPEN_568Small protein B; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA a [...]
emrE protein networkhttps://string-db.org/network/291272.BPEN_570Auxillary multidrug transport protein (SMR family); Ortholog to Escherichia coli bnum: b0543; MultiFun: Cell processes 5.6.4; Cell structure 6.1; Transport 4.2.A.7, 4.S.126.
pssA protein networkhttps://string-db.org/network/291272.BPEN_571Phosphatidylserine synthase; Ortholog to Escherichia coli bnum: b2585; MultiFun: Cell structure 6.1; Metabolism 1.6.1; CDP-diacylglycerol-serine O-phosphatidyltransferase.
purH protein networkhttps://string-db.org/network/291272.BPEN_575IMP cyclohydrolase; Bifunctional; ortholog to Escherichia coli bnum: b4006; MultiFun: Metabolism 1.5.2.1; Metabolism 1.7.33; phosphoribosylaminoimidazolecarboxamide formyltransferase.
rpoC protein networkhttps://string-db.org/network/291272.BPEN_576DNA-directed RNA polymerase, beta-prime-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/291272.BPEN_577DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplL protein networkhttps://string-db.org/network/291272.BPEN_57850S ribosomal subunit protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs t [...]
rplJ protein networkhttps://string-db.org/network/291272.BPEN_57950S ribosomal subunit protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal riboso [...]
rplA protein networkhttps://string-db.org/network/291272.BPEN_58050S ribosomal subunit protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/291272.BPEN_58150S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/291272.BPEN_582Transcription antitermination protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA [...]
secE protein networkhttps://string-db.org/network/291272.BPEN_583Preprotein translocase, membrane component; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocat [...]
tuf protein networkhttps://string-db.org/network/291272.BPEN_584Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
fusA protein networkhttps://string-db.org/network/291272.BPEN_585Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- [...]
rpsG protein networkhttps://string-db.org/network/291272.BPEN_58630S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subu [...]
rpsL protein networkhttps://string-db.org/network/291272.BPEN_58730S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.
pabA protein networkhttps://string-db.org/network/291272.BPEN_588Aminodeoxychorismate synthase subunit II; Component of p-aminobenzoate synthase multienzyme complex; ortholog to Escherichia coli bnum: b3360; MultiFun: Metabolism 1.5.3.2.
trpS protein networkhttps://string-db.org/network/291272.BPEN_589tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
rpe protein networkhttps://string-db.org/network/291272.BPEN_590Ribulose-phosphate 3-epimerase; Ortholog to Escherichia coli bnum: b3386; MultiFun: Metabolism 1.1.1, 1.7.3; Belongs to the ribulose-phosphate 3-epimerase family.
aroB protein networkhttps://string-db.org/network/291272.BPEN_5913-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquin [...]
aroK protein networkhttps://string-db.org/network/291272.BPEN_592Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
gntY protein networkhttps://string-db.org/network/291272.BPEN_593Membrane-bound protein in GNT I transport system; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the matur [...]
asd protein networkhttps://string-db.org/network/291272.BPEN_594Aspartate-semialdehyde dehydrogenase; Ortholog to Escherichia coli bnum: b3433; MultiFun: Metabolism 1.5.1.21; Metabolism 1.5.1.7, 1.5.1.8, 1.5.1.9; Belongs to the aspartate-semialdehyde dehydrog [...]
yhgN protein networkhttps://string-db.org/network/291272.BPEN_595Putative integral membrane protein; Ortholog to Escherichia coli bnum: b3434; MultiFun: Cell structure 6.1.
yigL protein networkhttps://string-db.org/network/291272.BPEN_596Putative hydrolase of the HAD superfamily; Ortholog to Escherichia coli bnum: b3826.
corA protein networkhttps://string-db.org/network/291272.BPEN_597Mg2+/Ni2+/Co2+ transport protein (Mg transport system I) (MIT family); Mediates influx of magnesium ions. Can also mediate cobalt and manganese uptake (By similarity). Alternates between open and [...]
yigB protein networkhttps://string-db.org/network/291272.BPEN_599Putative hydrolase of the HAD superfamily; Ortholog to Escherichia coli bnum: b3812.
dapF protein networkhttps://string-db.org/network/291272.BPEN_600Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...]
hemC protein networkhttps://string-db.org/network/291272.BPEN_601Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
hemD protein networkhttps://string-db.org/network/291272.BPEN_602Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
rho protein networkhttps://string-db.org/network/291272.BPEN_607Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
trxA protein networkhttps://string-db.org/network/291272.BPEN_608Thioredoxin 1, redox factor; Ortholog to Escherichia coli bnum: b3781; MultiFun: Metabolism 1.6.15.2; Belongs to the thioredoxin family.
ilvC protein networkhttps://string-db.org/network/291272.BPEN_609Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yie [...]
ilvA protein networkhttps://string-db.org/network/291272.BPEN_610Threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production [...]
ilvD protein networkhttps://string-db.org/network/291272.BPEN_611Dihydroxyacid dehydratase; Ortholog to Escherichia coli bnum: b3771; MultiFun: Metabolism 1.5.1.18; Belongs to the IlvD/Edd family.
ilvE protein networkhttps://string-db.org/network/291272.BPEN_612Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
ilvM protein networkhttps://string-db.org/network/291272.BPEN_613Acetolactate synthase II, small subunit; Ortholog to Escherichia coli bnum: b3769; MultiFun: Metabolism 1.5.1.18.
ilvG protein networkhttps://string-db.org/network/291272.BPEN_614Acetolactate synthase II, large subunit; Ortholog to Escherichia coli bnum: b3767; MultiFun: Metabolism 1.5.1.18; cryptic genes 10.
murI protein networkhttps://string-db.org/network/291272.BPEN_618Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
metF protein networkhttps://string-db.org/network/291272.BPEN_6195,10 methylenetetrahydrofolate reductase; Ortholog to Escherichia coli bnum: b3941; MultiFun: Metabolism 1.7.17; Belongs to the methylenetetrahydrofolate reductase family.
metB protein networkhttps://string-db.org/network/291272.BPEN_620Cystathionine gamma-synthase; Ortholog to Escherichia coli bnum: b3939; MultiFun: Metabolism 1.1.3.7, 1.5.1.9, 1.7.30.
rpmE protein networkhttps://string-db.org/network/291272.BPEN_62150S ribosomal subunit protein L31; Binds the 23S rRNA.
fpr protein networkhttps://string-db.org/network/291272.BPEN_622ferredoxin-NADP reductase; Ortholog to Escherichia coli bnum: b3924; MultiFun: Cell processes 5.6.2; Metabolism 1.7.1.
tpiA protein networkhttps://string-db.org/network/291272.BPEN_623Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
pfkA protein networkhttps://string-db.org/network/291272.BPEN_6246-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
cysE protein networkhttps://string-db.org/network/291272.BPEN_625Serine acetyltransferase; Ortholog to Escherichia coli bnum: b3607; MultiFun: Metabolism 1.5.1.12; Belongs to the transferase hexapeptide repeat family.
gpsA protein networkhttps://string-db.org/network/291272.BPEN_626Glycerol-3-phosphate dehydrogenase; Ortholog to Escherichia coli bnum: b3608; MultiFun: Metabolism 1.1.1.23, 1.7.6, 1.8.1; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
secB protein networkhttps://string-db.org/network/291272.BPEN_627Molecular chaperone in protein export; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor [...]
grxC protein networkhttps://string-db.org/network/291272.BPEN_628Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
yibN protein networkhttps://string-db.org/network/291272.BPEN_629Putative Rhodanese-related sulfurtransferases; Ortholog to Escherichia coli bnum: b3611.
hldD protein networkhttps://string-db.org/network/291272.BPEN_630ADP-L-Glycero-D-mannoheptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the [...]
rfaF protein networkhttps://string-db.org/network/291272.BPEN_631ADP-heptose; Ortholog to Escherichia coli bnum: b3620; MultiFun: Cell structure 6.3; Metabolism 1.6.3.2.
rfaC protein networkhttps://string-db.org/network/291272.BPEN_632ADP-heptose; Ortholog to Escherichia coli bnum: b3621; MultiFun: Cell structure 6.3; Metabolism 1.6.3.2.
kdtA protein networkhttps://string-db.org/network/291272.BPEN_633Kdo transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide [...]
coaD protein networkhttps://string-db.org/network/291272.BPEN_634CMP-deoxy-D-manno-octulosonate-lipid A transferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bac [...]
rpmG protein networkhttps://string-db.org/network/291272.BPEN_63550S ribosomal subunit protein L33; Ortholog to Escherichia coli bnum: b3636; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL33 famil [...]
rpmB protein networkhttps://string-db.org/network/291272.BPEN_63650S ribosomal subunit protein L28; Ortholog to Escherichia coli bnum: b3637; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL28 famil [...]
dfp protein networkhttps://string-db.org/network/291272.BPEN_6374'-phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothen [...]
dut protein networkhttps://string-db.org/network/291272.BPEN_638Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intrace [...]
yicC protein networkhttps://string-db.org/network/291272.BPEN_639Putative stress-induced protein; Ortholog to Escherichia coli bnum: b3644.
BPEN_640 protein networkhttps://string-db.org/network/291272.BPEN_640Putative transcriptional regulator protein (MarR family).
gmk protein networkhttps://string-db.org/network/291272.BPEN_641Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
rpoZ protein networkhttps://string-db.org/network/291272.BPEN_642DNA-directed RNA polymerase, subunit K/omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and [...]
glnA protein networkhttps://string-db.org/network/291272.BPEN_643Glutamine synthetase; Ortholog to Escherichia coli bnum: b3870; MultiFun: Metabolism 1.5.1.2, 1.8.3.
yihA protein networkhttps://string-db.org/network/291272.BPEN_644Probable GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB G [...]
polA protein networkhttps://string-db.org/network/291272.BPEN_645DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
dsbA protein networkhttps://string-db.org/network/291272.BPEN_646Periplasmic protein disulfide isomerase I, disulfide bond formation; Ortholog to Escherichia coli bnum: b3860; MultiFun: Cell processes 5.5; Information transfer 2.3.4.
ubiD protein networkhttps://string-db.org/network/291272.BPEN_6473-octaprenyl-4-hydroxybenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
ubiB protein networkhttps://string-db.org/network/291272.BPEN_6482-octaprenylphenol hydroxylase of ubiquinone biosynthetic pathway; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
ubiE protein networkhttps://string-db.org/network/291272.BPEN_6492-octaprenyl-6-methoxy-1,4-benzoquinone methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1, [...]
yigN protein networkhttps://string-db.org/network/291272.BPEN_650Putative membrane protein; Ortholog to Escherichia coli bnum: b3832.
udp protein networkhttps://string-db.org/network/291272.BPEN_651Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as c [...]
metE protein networkhttps://string-db.org/network/291272.BPEN_6525-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; [...]
rpoH protein networkhttps://string-db.org/network/291272.BPEN_653RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involve [...]
ftsY protein networkhttps://string-db.org/network/291272.BPEN_654Cell division protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle [...]
yhhF protein networkhttps://string-db.org/network/291272.BPEN_655Putative methyltransferase with SAM-dependent methyltransferase domain; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransfe [...]
pgi protein networkhttps://string-db.org/network/291272.BPEN_656Glucose-6-phosphate isomerase; Ortholog to Escherichia coli bnum: b4025; MultiFun: Metabolism 1.3.1, 1.7.8.
metA protein networkhttps://string-db.org/network/291272.BPEN_657Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.