Organism Overview: Haemophilus influenzae


 
gapA protein networkhttps://string-db.org/network/71421.HI_0001Glyceraldehyde-3-phosphate dehydrogenase (gapdH); Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first r [...]
HI_0002 protein networkhttps://string-db.org/network/71421.HI_0002Long chain fatty acid coA ligase, putative; Similar to GB:AE000782 percent identity: 34.58; identified by sequence similarity; putative.
HI_0003 protein networkhttps://string-db.org/network/71421.HI_0003Conserved hypothetical protein; Similar to GB:L10328 SP:P09997 PID:290545 PID:41648 GB:U00096 percent identity: 32.69; identified by sequence similarity; putative.
ybeY protein networkhttps://string-db.org/network/71421.HI_0004Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
fdhD protein networkhttps://string-db.org/network/71421.HI_0005fdhD protein (fdhD); Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH [...]
fdxH protein networkhttps://string-db.org/network/71421.HI_0007Formate dehydrogenase, beta subunit (fdxH); Allows to use formate as major electron donor during aerobic respiration. The beta chain is an electron transfer unit containing 4 cysteine clusters in [...]
fdxI protein networkhttps://string-db.org/network/71421.HI_0008Formate dehydrogenase, gamma subunit (fdxI); Allows to use formate as major electron donor during anaerobic respiration. Subunit gamma is probably the cytochrome b556(FDO) component of the format [...]
fdhE protein networkhttps://string-db.org/network/71421.HI_0009fdhE protein (fdhE); Necessary for formate dehydrogenase activity; Belongs to the FdhE family.
rimI protein networkhttps://string-db.org/network/71421.HI_0010Ribosomal-protein-alanine acetyltransferase (rimI); Acetylates the N-terminal alanine of ribosomal protein S18.
holD protein networkhttps://string-db.org/network/71421.HI_0011DNA polymerase III, psi subunit (holD); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5 [...]
rsmC protein networkhttps://string-db.org/network/71421.HI_0012Conserved hypothetical protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.
era protein networkhttps://string-db.org/network/71421.HI_0013GTP-binding protein (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly a [...]
rnc protein networkhttps://string-db.org/network/71421.HI_0014Ribonuclease III (rnc); Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes [...]
lepB protein networkhttps://string-db.org/network/71421.HI_0015Signal peptidase I (lepB); Similar to GB:K00426 SP:P00803 PID:146600 PID:987643 GB:U00096 percent identity: 46.31; identified by sequence similarity; putative; Belongs to the peptidase S26 family [...]
lepA protein networkhttps://string-db.org/network/71421.HI_0016GTP-binding membrane protein (lepA); Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing [...]
grcA protein networkhttps://string-db.org/network/71421.HI_0017Conserved hypothetical protein; Acts as a radical domain for damaged PFL and possibly other radical proteins.
ung protein networkhttps://string-db.org/network/71421.HI_0018Uracil DNA glycosylase (ung); Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
miaB protein networkhttps://string-db.org/network/71421.HI_0019Conserved hypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at positi [...]
HI_0020 protein networkhttps://string-db.org/network/71421.HI_0020Transport protein, putative; Similar to GB:U00096 SP:P75763 PID:1786986 percent identity: 59.91; identified by sequence similarity; putative.
citXG protein networkhttps://string-db.org/network/71421.HI_0021citG protein (citG); Bifunctional enzyme that catalyzes formation of 2-(5''- triphosphoribosyl)-3'-dephosphocoenzyme-A, and then the transfer of this prosthetic group precursor to the apo-acyl ca [...]
citF protein networkhttps://string-db.org/network/71421.HI_0022Citrate lyase, alpha chain (citF); Represents a citrate:acetyl-ACP transferase.
citE protein networkhttps://string-db.org/network/71421.HI_0023Citrate lyase, beta chain (citE); Represents a citryl-ACP lyase; Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
citD protein networkhttps://string-db.org/network/71421.HI_0024Citrate lyase, gamma chain (citD); Covalent carrier of the coenzyme of citrate lyase.
citC protein networkhttps://string-db.org/network/71421.HI_0025Citrate lyase ligase (citC); Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.
lipA protein networkhttps://string-db.org/network/71421.HI_0026Lipoate biosynthesis protein A (lipA); Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-de [...]
lipB protein networkhttps://string-db.org/network/71421.HI_0027Lipoate biosynthesis protein B (lipB); Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipo [...]
HI_0028 protein networkhttps://string-db.org/network/71421.HI_0028Conserved hypothetical protein; Similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548 percent identity: 50.59; identified by sequence similarity; putative; Belongs to the UPF0250 family [...]
dacA protein networkhttps://string-db.org/network/71421.HI_0029Penicillin-binding protein 5 (dacA); Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Belongs to the peptidase S11 family.
rlpA protein networkhttps://string-db.org/network/71421.HI_0030Lipoprotein, putative; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
mrdB protein networkhttps://string-db.org/network/71421.HI_0031Rod shape-determining protein (rodA); Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
mrdA protein networkhttps://string-db.org/network/71421.HI_0032Penicillin-binding protein 2 (pbp2); Catalyzes cross-linking of the peptidoglycan cell wall.
rlmH protein networkhttps://string-db.org/network/71421.HI_0033Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
rsfS protein networkhttps://string-db.org/network/71421.HI_0034Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 3 [...]
HI_0035 protein networkhttps://string-db.org/network/71421.HI_0035Conserved hypothetical protein; Similar to GB:L10328 SP:P29211 GB:M94104 PID:290534 PID:147371 percent identity: 63.41; identified by sequence similarity; putative.
HI_0036 protein networkhttps://string-db.org/network/71421.HI_0036ABC transporter, ATP-binding protein; Similar to SP:Q50614 PID:1483552 percent identity: 42.52; identified by sequence similarity; putative.
mreB protein networkhttps://string-db.org/network/71421.HI_0037Rod shape-determining protein (mreB); Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and [...]
mreC protein networkhttps://string-db.org/network/71421.HI_0038Rod shape-determining protein (mreC); Involved in formation and maintenance of cell shape.
mreD protein networkhttps://string-db.org/network/71421.HI_0039Rod shape-determining protein (mreD); Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins (By similarity); Belongs to [...]
HI_0040 protein networkhttps://string-db.org/network/71421.HI_0040Conserved hypothetical protein; Similar to PID:1944176 percent identity: 47.58; identified by sequence similarity; putative.
xthA protein networkhttps://string-db.org/network/71421.HI_0041Exodeoxyribonuclease III (xthA); Major apurinic-apyrimidinic endonuclease of E.coli. It removes the damaged DNA at cytosines and guanines by cleaving on the 3'-side of the AP site by a beta-elimi [...]
HI_0042 protein networkhttps://string-db.org/network/71421.HI_0042Conserved hypothetical protein; Similar to SP:P39219 GB:U00096 PID:1786244 percent identity: 34.95; identified by sequence similarity; putative.
HI_0043 protein networkhttps://string-db.org/network/71421.HI_0043Conserved hypothetical transmembrane protein; Similar to SP:P45525 GB:U00096 PID:1787582 percent identity: 42.69; identified by sequence similarity; putative.
HI_0044 protein networkhttps://string-db.org/network/71421.HI_0044Conserved hypothetical transmembrane protein; Similar to SP:P06967 GB:X00547 PID:41284 GB:U00096 PID:1787205 percent identity: 61.47; identified by sequence similarity; putative.
HI_0045 protein networkhttps://string-db.org/network/71421.HI_0045Conserved hypothetical protein; Similar to GB:U14003 SP:P39187 PID:471102 PID:537057 GB:U00096 percent identity: 40.66; identified by sequence similarity; putative.
yjdM protein networkhttps://string-db.org/network/71421.HI_0046Alkylphosphonate uptake protein (phnA); Similar to SP:P16680 GB:U14003 PID:147194 PID:536952 GB:U00096 percent identity: 61.32; identified by sequence similarity; putative; Belongs to the YjdM fa [...]
eda protein networkhttps://string-db.org/network/71421.HI_00474-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase (eda); Similar to GB:L20897 GB:M87458 GB:X63694 GB:X68871 PID:145827 percent identity: 37.31; identified by sequence si [...]
HI_0048 protein networkhttps://string-db.org/network/71421.HI_0048Oxidoreductase; Similar to GB:AL009126 percent identity: 48.39; identified by sequence similarity; putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
kdgK protein networkhttps://string-db.org/network/71421.HI_00492-dehydro-3-deoxygluconokinase (kdgK); Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG).
HI_0050 protein networkhttps://string-db.org/network/71421.HI_0050Conserved hypothetical transmembrane protein; Similar to SP:P37675 PID:466716 GB:U00096 PID:1790003 percent identity: 47.93; identified by sequence similarity; putative.
HI_0051 protein networkhttps://string-db.org/network/71421.HI_0051Conserved hypothetical transmembrane protein; Similar to SP:P37674 PID:466715 GB:U00096 PID:1790002 percent identity: 28.15; identified by sequence similarity; putative.
HI_0052 protein networkhttps://string-db.org/network/71421.HI_0052Conserved hypothetical protein; Similar to SP:P37676 PID:466717 GB:U00096 PID:1790004 percent identity: 27.19; identified by sequence similarity; putative.
HI_0053 protein networkhttps://string-db.org/network/71421.HI_0053Zinc-type alcohol dehydrogenase; Similar to GB:M96947 SP:Q06004 PID:304153 GB:AL009126 percent identity: 34.47; identified by sequence similarity; putative.
uxuR protein networkhttps://string-db.org/network/71421.HI_0054Uxu operon regulator (uxuR); Repressor for the uxuRBA operon.
uxuA protein networkhttps://string-db.org/network/71421.HI_0055Mannonate dehydratase (uxuA); Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
HI_0056 protein networkhttps://string-db.org/network/71421.HI_0056Conserved hypothetical transmembrane protein; Similar to PID:882725 GB:U00096 PID:1789197 percent identity: 61.70; identified by sequence similarity; putative.
uvrC protein networkhttps://string-db.org/network/71421.HI_0057Excinuclease ABC, subunit C (uvrC); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is r [...]
kdsB protein networkhttps://string-db.org/network/71421.HI_00583-deoxy-D-manno-octulosonate cytidylyltransferase (kdsB); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
lpxK protein networkhttps://string-db.org/network/71421.HI_0059Conserved hypothetical protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis- [...]
msbA protein networkhttps://string-db.org/network/71421.HI_0060ABC transporter, ATP-binding protein (msbA); Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form [...]
rec2 protein networkhttps://string-db.org/network/71421.HI_0061Recombination protein (rec2); Might contribute to transformation as a member of a membrane- bound pore complex at the base of the transformasome. It could directly interact with transforming DNA [...]
dksA protein networkhttps://string-db.org/network/71421.HI_0062dnaK suppressor protein (dksA); Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of sev [...]
pcnB protein networkhttps://string-db.org/network/71421.HI_0063poly(A) polymerase (pcnB); Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through inf [...]
folK protein networkhttps://string-db.org/network/71421.HI_00642-amino-4-hydroxy-6- hydroxymethyldihydropteridine-pyrophosphokinase (folK); Similar to GB:D26562 SP:P26281 GB:L06495 PID:146013 PID:473801 percent identity: 56.33; identified by sequence similar [...]
tsaE protein networkhttps://string-db.org/network/71421.HI_0065Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the [...]
amiB protein networkhttps://string-db.org/network/71421.HI_0066N-acetylmuramoyl-L-alanine amidase, putative; Cell-wall hydrolase involved in septum cleavage during cell division; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
mutL protein networkhttps://string-db.org/network/71421.HI_0067DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matc [...]
miaA protein networkhttps://string-db.org/network/71421.HI_0068tRNA delta(2)-isopentenylpyrophosphate transferase (trpX); Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leadin [...]
glnE protein networkhttps://string-db.org/network/71421.HI_0069Glutamate-ammonia-ligase adenylyltransferase (glnE); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are [...]
recN protein networkhttps://string-db.org/network/71421.HI_0070DNA repair protein (recN); May be involved in recombinational repair of damaged DNA.
grpE protein networkhttps://string-db.org/network/71421.HI_0071Heat shock protein (grpE); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It i [...]
nadK protein networkhttps://string-db.org/network/71421.HI_0072Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylatio [...]
HI_0073 protein networkhttps://string-db.org/network/71421.HI_0073Predicted coding region HI0073; Hypothetical protein; identified by GeneMark; putative.
HI_0074 protein networkhttps://string-db.org/network/71421.HI_0074Predicted coding region HI0074; Hypothetical protein; identified by GeneMark; putative.
nrdD protein networkhttps://string-db.org/network/71421.HI_0075Anaerobic ribonucleoside-triphosphate reductase (nrdD); Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. Belongs to the anae [...]
tesB protein networkhttps://string-db.org/network/71421.HI_0076acyl-CoA thioesterase II (tesB); Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known (By similarity); Belongs to the C/M/P thioester hydrolase family.
HI_0077 protein networkhttps://string-db.org/network/71421.HI_0077Predicted coding region HI0077; Hypothetical protein; identified by GeneMark; putative.
cysS protein networkhttps://string-db.org/network/71421.HI_0078cysteinyl-tRNA synthetase (cysS); Similar to GB:M59381 SP:P21888 GB:X56234 GB:X59293 PID:145692 percent identity: 75.65; identified by sequence similarity; putative; Belongs to the class-I aminoa [...]
ppiB protein networkhttps://string-db.org/network/71421.HI_0079Peptidyl-prolyl cis-trans isomerase B (ppiB); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
HI_0080 protein networkhttps://string-db.org/network/71421.HI_0080Conserved hypothetical protein; Similar to GB:U00096 PID:2367279 percent identity: 43.04; identified by sequence similarity; putative; To E.coli YifN.
HI_0081 protein networkhttps://string-db.org/network/71421.HI_0081Conserved hypothetical protein; Similar to GB:U14003 SP:P39408 PID:537218 GB:U00096 PID:1790838 percent identity: 54.82; identified by sequence similarity; putative.
HI_0082 protein networkhttps://string-db.org/network/71421.HI_0082Predicted coding region HI0082; Hypothetical protein; identified by GeneMark; putative.
HI_0083 protein networkhttps://string-db.org/network/71421.HI_0083Predicted coding region HI0083; Hypothetical protein; identified by GeneMark; putative.
trxA protein networkhttps://string-db.org/network/71421.HI_0084Thioredoxin (trxM); Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
ddh protein networkhttps://string-db.org/network/71421.HI_0085D-lactate dehydrogenase, fermentative (ldhA); Similar to PID:1049265 SP:P52643 GB:U00096 PID:1742253 PID:1742259 percent identity: 70.86; identified by sequence similarity; putative; Belongs to t [...]
metB protein networkhttps://string-db.org/network/71421.HI_0086Cystathionine gamma-synthase (metB); Catalyzes the formation of L-cystathionine from O-succinyl-L- homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, cat [...]
thrC protein networkhttps://string-db.org/network/71421.HI_0087Threonine synthase (thrC); Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
thrB protein networkhttps://string-db.org/network/71421.HI_0088Homoserine kinase (thrB); Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
thrA protein networkhttps://string-db.org/network/71421.HI_0089Aspartokinase I / homoserine dehydrogenase I (thrA); Similar to SP:P00561 GB:M10644 GB:V00360 GB:V00361 PID:147979 percent identity: 62.21; identified by sequence similarity; putative; In the C-t [...]
HI_0090 protein networkhttps://string-db.org/network/71421.HI_0090Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
glxK protein networkhttps://string-db.org/network/71421.HI_0091Conserved hypothetical protein; Similar to SP:P42100 PID:563934 PID:904179 GB:AL009126 percent identity: 59.46; identified by sequence similarity; putative.
HI_0092 protein networkhttps://string-db.org/network/71421.HI_0092Predicted coding region HI0092; Hypothetical protein; identified by GeneMark; putative.
HI_0093 protein networkhttps://string-db.org/network/71421.HI_0093Conserved hypothetical protein; Similar to SP:P37047 GB:U00096 PID:1552740 PID:1786357 percent identity: 35.90; identified by sequence similarity; putative; Belongs to the CdaR family.
HI_0094 protein networkhttps://string-db.org/network/71421.HI_0094Predicted coding region HI0094; Hypothetical protein; identified by GeneMark; putative.
HI_0095 protein networkhttps://string-db.org/network/71421.HI_0095Conserved hypothetical protein; Similar to GP:2104289 percent identity: 34.43; identified by sequence similarity; putative.
HI_0096 protein networkhttps://string-db.org/network/71421.HI_0096Predicted coding region HI0096; Hypothetical protein; identified by GeneMark; putative.
fbpA protein networkhttps://string-db.org/network/71421.HI_0097iron(III) ABC transporter, periplasmic-binding protein (hitA); Part of the ABC transporter complex FbpABC (TC 3.A.1.10.1) involved in Fe(3+) ions import. This protein specifically binds Fe(3+) an [...]
fbpB2 protein networkhttps://string-db.org/network/71421.HI_0098iron(III) ABC transporter, permease protein (hitB); Part of the ABC transporter complex FbpABC (TC 3.A.1.10.1) involved in Fe(3+) ions import. Probably responsible for the translocation of the su [...]
fbpC2 protein networkhttps://string-db.org/network/71421.HI_0099iron(III) ABC transporter, ATP-binding protein (hitC); Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.
HI_0100 protein networkhttps://string-db.org/network/71421.HI_0100Predicted coding region HI0100; Hypothetical protein; identified by GeneMark; putative.
HI_0101 protein networkhttps://string-db.org/network/71421.HI_0101Predicted coding region HI0101; Hypothetical protein; identified by GeneMark; putative.
dapE protein networkhttps://string-db.org/network/71421.HI_0102Succinyl-diaminopimelate desuccinylase (dapE); Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate invo [...]
HI_0103 protein networkhttps://string-db.org/network/71421.HI_0103Conserved hypothetical protein; Similar to SP:P24178 GB:X57403 PID:41233 GB:U00096 PID:1788815 percent identity: 48.70; identified by sequence similarity; putative; Belongs to the ArsC family.
htpG protein networkhttps://string-db.org/network/71421.HI_0104Heat shock protein (htpG); Molecular chaperone. Has ATPase activity.
HI_0105 protein networkhttps://string-db.org/network/71421.HI_0105Conserved hypothetical protein; Similar to GB:U00096 SP:P75743 PID:1786928 percent identity: 64.26; identified by sequence similarity; putative.
ffh protein networkhttps://string-db.org/network/71421.HI_0106Signal recognition particle protein (ffh); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome [...]
HI_0107 protein networkhttps://string-db.org/network/71421.HI_0107Conserved hypothetical protein; Similar to GB:U00096 PID:1788966 percent identity: 64.81; identified by sequence similarity; putative.
HI_0108 protein networkhttps://string-db.org/network/71421.HI_0108Conserved hypothetical protein; Similar to GB:U14003 SP:P39402 PID:537207 GB:U00096 PID:1790826 percent identity: 39.25; identified by sequence similarity; putative.
HI_0109 protein networkhttps://string-db.org/network/71421.HI_0109Predicted coding region HI0109; Hypothetical protein; identified by GeneMark; putative.
serS protein networkhttps://string-db.org/network/71421.HI_0110seryl-tRNA synthetase (serS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be f [...]
gst protein networkhttps://string-db.org/network/71421.HI_0111Glutathione transferase (bphH); Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Beta family.
HI_0112 protein networkhttps://string-db.org/network/71421.HI_0112Predicted coding region HI0112; Hypothetical protein; identified by GeneMark; putative; Belongs to the IS150/IS1296 orfA family.
tdhA protein networkhttps://string-db.org/network/71421.HI_0113Hemin receptor (hemR); Heme receptor; Belongs to the TonB-dependent receptor family.
tcdA protein networkhttps://string-db.org/network/71421.HI_0118Conserved hypothetical protein; Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginnin [...]
znuA protein networkhttps://string-db.org/network/71421.HI_0119Conserved hypothetical protein; Involved in the high-affinity zinc uptake transport system. Belongs to the bacterial solute-binding protein 9 family.
HI_0120 protein networkhttps://string-db.org/network/71421.HI_0120Predicted coding region HI0120; Hypothetical protein; identified by GeneMark; putative.
mpl protein networkhttps://string-db.org/network/71421.HI_0121Conserved hypothetical protein; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamil [...]
metC protein networkhttps://string-db.org/network/71421.HI_0122Cystathionine beta-lyase (metC); Catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis.
pgsA protein networkhttps://string-db.org/network/71421.HI_0123Phosphatidylglycerophosphate synthase (pgsA); This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I fa [...]
ppa protein networkhttps://string-db.org/network/71421.HI_0124Inorganic pyrophosphatase (ppa); Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
HI_0125 protein networkhttps://string-db.org/network/71421.HI_0125Conserved hypothetical protein; Similar to SP:P32702 PID:396399 GB:U00096 PID:1790499 percent identity: 75.90; identified by sequence similarity; putative.
fbpC1 protein networkhttps://string-db.org/network/71421.HI_0126Ferric ABC transporter, ATP-binding protein (afuC); Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.
fbpB1 protein networkhttps://string-db.org/network/71421.HI_0129Predicted coding region HI0129; Part of the ABC transporter complex FbpABC (TC 3.A.1.10.1) involved in Fe(3+) ions import. Probably responsible for the translocation of the substrate across the m [...]
HI_0131 protein networkhttps://string-db.org/network/71421.HI_0131afuA protein; Similar to PID:1469286 PID:1477455 percent identity: 74.57; identified by sequence similarity; putative.
udk protein networkhttps://string-db.org/network/71421.HI_0132Uridine kinase (udk); Similar to SP:P31218 GB:X71492 PID:296947 GB:U00096 PID:1736770 percent identity: 67.82; identified by sequence similarity; putative.
dcd protein networkhttps://string-db.org/network/71421.HI_0133Deoxycytidine triphosphate deaminase (dcd); Catalyzes the deamination of dCTP to dUTP.
HI_0134 protein networkhttps://string-db.org/network/71421.HI_0134Predicted coding region HI0134; Hypothetical protein; identified by GeneMark; putative.
sotB protein networkhttps://string-db.org/network/71421.HI_0135Conserved hypothetical transmembrane protein; Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites [...]
der protein networkhttps://string-db.org/network/71421.HI_0136GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase [...]
dnaQ protein networkhttps://string-db.org/network/71421.HI_0137DNA polymerase III, epsilon subunit (dnaQ); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editi [...]
rnhA protein networkhttps://string-db.org/network/71421.HI_0138Ribonuclease H (rnh); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
ompP2 protein networkhttps://string-db.org/network/71421.HI_0139Outer membrane protein P2 (ompP2); Forms pores that allow passive diffusion of small molecules across the outer membrane.
nagA protein networkhttps://string-db.org/network/71421.HI_0140N-acetylglucosamine-6-phosphate deacetylase (nagA); Involved in the first committed step in the biosynthesis of amino-sugar-nucleotides. Catalyzes the hydrolysis of the N-acetyl group of N-acetyl [...]
nagB protein networkhttps://string-db.org/network/71421.HI_0141Glucosamine-6-phosphate isomerase (nagB); Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
nanA protein networkhttps://string-db.org/network/71421.HI_0142N-acetylneuraminate lyase (nanA); Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base inte [...]
HI_0143 protein networkhttps://string-db.org/network/71421.HI_0143Conserved hypothetical protein; Similar to GB:M81878 SP:P26833 PID:144859 percent identity: 34.08; identified by sequence similarity; putative.
nanK protein networkhttps://string-db.org/network/71421.HI_0144Glucose kinase, putative; Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P; Belongs to the ROK (NagC/XylR) family. NanK subfamily.
nanE protein networkhttps://string-db.org/network/71421.HI_0145Conserved hypothetical protein; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
siaP protein networkhttps://string-db.org/network/71421.HI_0146Conserved hypothetical protein; Part of the tripartite ATP-independent periplasmic (TRAP) transport system SiaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [...]
siaT protein networkhttps://string-db.org/network/71421.HI_0147Conserved hypothetical transmembrane protein; Part of the tripartite ATP-independent periplasmic (TRAP) transport system SiaPT involved in the uptake of sialic acid. In the N-terminal section; be [...]
nanM protein networkhttps://string-db.org/network/71421.HI_0148Conserved hypothetical protein; Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta- anomer, accelerating the equilibrium between the alpha- and beta- anomers. Probably facilitates sialid [...]
HI_0148.1 protein networkhttps://string-db.org/network/71421.HI_0148.1Predicted coding region HI0148.1; Brute Force ORF; identified by GeneMark; putative.
HI_0149 protein networkhttps://string-db.org/network/71421.HI_0149Predicted coding region HI0149; Hypothetical protein; identified by GeneMark; putative.
hflC protein networkhttps://string-db.org/network/71421.HI_0150hflC protein (hflC); HflC and HflK could regulate a protease.
hflK protein networkhttps://string-db.org/network/71421.HI_0151hflK protein (hflK); HflC and HflK could encode or regulate a protease.
HI_0152 protein networkhttps://string-db.org/network/71421.HI_0152Predicted coding region HI0152; May transfer the 4'-phosphopantetheine moiety from coenzyme A (CoA) to a serine residue of a carrier protein domain; Belongs to the P-Pant transferase superfamily. [...]
acpP protein networkhttps://string-db.org/network/71421.HI_0154Acyl carrier protein (acpP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
fabG protein networkhttps://string-db.org/network/71421.HI_01553-ketoacyl-acyl carrier protein reductase (fabG); Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongat [...]
fabD protein networkhttps://string-db.org/network/71421.HI_0156Malonyl CoA-acyl carrier protein transacylase (fabD); Similar to GB:M87040 SP:P25715 GB:Z11565 PID:145887 PID:41364 percent identity: 70.97; identified by sequence similarity; putative; Belongs t [...]
fabH protein networkhttps://string-db.org/network/71421.HI_0157beta-ketoacyl-ACP synthase III (fabH); Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condens [...]
rpmF protein networkhttps://string-db.org/network/71421.HI_0158Ribosomal protein L32 (rpL32); Similar to GB:M29698 SP:P02435 PID:147712 GB:U00096 PID:1651531 percent identity: 77.19; identified by sequence similarity; putative; Belongs to the bacterial ribos [...]
yceD protein networkhttps://string-db.org/network/71421.HI_0159Conserved hypothetical protein; Plays a role in synthesis, processing and/or stability of 23S rRNA.
psd protein networkhttps://string-db.org/network/71421.HI_0160Phosphatidylserine decarboxylase proenzyme (psd); Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
gor protein networkhttps://string-db.org/network/71421.HI_0161Glutathione reductase (gor); Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
HI_0162 protein networkhttps://string-db.org/network/71421.HI_0162Lipoprotein, putative; Similar to GB:U00096 PID:1773118 PID:1786637 percent identity: 25.82; identified by sequence similarity; putative.
bolA protein networkhttps://string-db.org/network/71421.HI_0163Transcriptional regulator, putative (bolA); Transcriptional regulator that plays an important role in general stress response.
nqrA protein networkhttps://string-db.org/network/71421.HI_0164NADH:ubiquinone oxidoreducatase subunit A, Na translocating; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions [...]
nqrB protein networkhttps://string-db.org/network/71421.HI_0166NADH:ubiquinone oxidoreductase, subunit B (nqrB); NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the c [...]
nqrC protein networkhttps://string-db.org/network/71421.HI_0167NADH:ubiquinone oxidoreductase, Na translocating; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the c [...]
nqrD protein networkhttps://string-db.org/network/71421.HI_0168NADH:ubiquinone oxidoreductase, Na translocating; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the c [...]
nqrE protein networkhttps://string-db.org/network/71421.HI_0170NADH:ubiquinone oxidoreductase, Na translocating; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the c [...]
nqrF protein networkhttps://string-db.org/network/71421.HI_0171Nqr6 subunit of Na-translocating NADH-quinone reductase complex beta-subunit (nqr6); NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the [...]
apbE protein networkhttps://string-db.org/network/71421.HI_0172Lipoprotein, putative; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein such [...]
HI_0173 protein networkhttps://string-db.org/network/71421.HI_0173Predicted coding region HI0173; Hypothetical protein; identified by GeneMark; putative.
mnmA protein networkhttps://string-db.org/network/71421.HI_0174Conserved hypothetical protein; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
HI_0175 protein networkhttps://string-db.org/network/71421.HI_0175Conserved hypothetical protein; Multicopper oxidase with polyphenol oxidase activity.
rluD protein networkhttps://string-db.org/network/71421.HI_0176sfhB protein (sfhB); Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family.
bamD protein networkhttps://string-db.org/network/71421.HI_0177Lipoprotein, putative; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
pe protein networkhttps://string-db.org/network/71421.HI_0178Predicted coding region HI0178; Acts as a multifunctional adhesin involved in direct interactions with host epithelial cells and host proteins.
pflA protein networkhttps://string-db.org/network/71421.HI_0179Pyruvate formate-lyase activating enzyme (act); Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced [...]
pflB protein networkhttps://string-db.org/network/71421.HI_0180Formate acetyltransferase (pfl); Similar to GB:X08035 SP:P09373 PID:42370 GB:U00096 PID:1651427 percent identity: 86.09; identified by sequence similarity; putative.
focA protein networkhttps://string-db.org/network/71421.HI_0181Formate transporter; Involved in the bidirectional transport of formate. Belongs to the FNT transporter (TC 2.A.44) family.
nagK protein networkhttps://string-db.org/network/71421.HI_0182Sugar kinase, putative; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
HI_0183 protein networkhttps://string-db.org/network/71421.HI_0183Amino acid carrier protein, putative; Similar to PID:757741 SP:Q45068 PID:1405464 GB:AL009126 percent identity: 47.97; identified by sequence similarity; putative.
HI_0184 protein networkhttps://string-db.org/network/71421.HI_0184Esterase; Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
frmA protein networkhttps://string-db.org/network/71421.HI_0185Alcohol dehydrogenase, class III (adhC); Similar to SP:P25437 PID:887431 GB:U00096 PID:1786552 PID:2443392 percent identity: 89.97; identified by sequence similarity; putative; Belongs to the zin [...]
HI_0186 protein networkhttps://string-db.org/network/71421.HI_0186Transcriptional regulator, putative; Similar to GB:D26185 SP:P37510 PID:467364 GB:AL009126 percent identity: 43.40; identified by sequence similarity; putative.
tatC protein networkhttps://string-db.org/network/71421.HI_0188Conserved hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide [...]
gdhA protein networkhttps://string-db.org/network/71421.HI_0189Glutamate dehydrogenase (gdhA); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.
fur protein networkhttps://string-db.org/network/71421.HI_0190Ferric uptake regulation protein (fur); Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
fldA protein networkhttps://string-db.org/network/71421.HI_0191Flavodoxin (fldA); Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
seqA protein networkhttps://string-db.org/network/71421.HI_0192seqA protein (seqA); Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome pe [...]
HI_0193 protein networkhttps://string-db.org/network/71421.HI_0193Esterase/lipase, putative; Similar to GB:U00096 PID:1786902 percent identity: 43.65; identified by sequence similarity; putative; Belongs to the DmpD/TodF/XylF esterase family.
menE protein networkhttps://string-db.org/network/71421.HI_0194O-succinylbenzoate--CoA ligase (menE); Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
HI_0195.1 protein networkhttps://string-db.org/network/71421.HI_0195.1Conserved hypothetical transmembrane protein (aefA); Similar to GB:U00096 SP:P77338 PID:1707458 PID:1773147 PID:1786670 percent identity: 37.35; identified by sequence similarity; putative.
aroC protein networkhttps://string-db.org/network/71421.HI_0196Chorismate synthase (aroC); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the bran [...]
mepA protein networkhttps://string-db.org/network/71421.HI_0197Penicillin-insensitive murein endopeptidase (mepA); Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in [...]
HI_0198 protein networkhttps://string-db.org/network/71421.HI_0198Conserved hypothetical transmembrane protein; Similar to SP:P14008 PID:41996 GB:U00096 PID:1788667 percent identity: 53.69; identified by sequence similarity; putative.
lpxM protein networkhttps://string-db.org/network/71421.HI_0199Lipid A biosynthesis (kdo)2-(lauroyl)-lipid IVA acyltransferase (msbB); Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2 [...]
selD protein networkhttps://string-db.org/network/71421.HI_0200Selenide, water dikinase (selD); Synthesizes selenophosphate from selenide and ATP.
rplS protein networkhttps://string-db.org/network/71421.HI_0201Ribosomal protein L19 (rpL19); This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
trmD protein networkhttps://string-db.org/network/71421.HI_0202tRNA (guanine-N1)-methyltransferase (trmD); Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rimM protein networkhttps://string-db.org/network/71421.HI_0203Conserved hypothetical protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. [...]
rpsP protein networkhttps://string-db.org/network/71421.HI_0204Ribosomal protein S16 (rpS16); Similar to SP:P02372 PID:43143 GB:U00096 PID:1788961 percent identity: 70.73; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protei [...]
HI_0205 protein networkhttps://string-db.org/network/71421.HI_0205Predicted coding region HI0205; Hypothetical protein; identified by GeneMark; putative.
HI_0206 protein networkhttps://string-db.org/network/71421.HI_02065'-nucleotidase, putative; Degrades NAD into adenosine and nicotinamide riboside, the latter being subsequently internalized by a specific permease. Also endowed with NAD(P) pyrophosphatase activ [...]
aroK protein networkhttps://string-db.org/network/71421.HI_0207Shikimic acid kinase I (aroK); Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
aroB protein networkhttps://string-db.org/network/71421.HI_02083-dehydroquinate synthase (aroB); Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehy [...]
dam protein networkhttps://string-db.org/network/71421.HI_0209DNA adenine methylase (dam); Methylates DNA within the sequence GATC. Directly involved in methyl-directed DNA mismatch repair; Belongs to the N(4)/N(6)-methyltransferase family.
pgpB protein networkhttps://string-db.org/network/71421.HI_0211Phosphatidylglycerophosphatase B (pgpB); Catalyzes the dephosphorylation of diacylglycerol diphosphate (DGPP) to phosphatidate (PA) and the subsequent dephosphorylation of PA to diacylglycerol (D [...]
ribA protein networkhttps://string-db.org/network/71421.HI_0212GTP cyclohydrolase II (ribA); Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase I [...]
HI_0213 protein networkhttps://string-db.org/network/71421.HI_0213Oligopeptide transporter, periplasmic-binding protein, putative; Part of a binding-protein-dependent transport system. Belongs to the bacterial solute-binding protein 5 family.
HI_0213.1 protein networkhttps://string-db.org/network/71421.HI_0213.1Predicted coding region HI0213.1; Brute Force ORF; identified by GeneMark; putative.
prlC protein networkhttps://string-db.org/network/71421.HI_0214Oligopeptidase A (prlC); May play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. Can cleave N-acetyl-L-Ala(4) (By similar [...]
HI_0216 protein networkhttps://string-db.org/network/71421.HI_0216Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipar [...]
HI_0217 protein networkhttps://string-db.org/network/71421.HI_0217Conserved hypothetical protein; Similar to PID:984584 GB:U00096 SP:Q47152 PID:1552796 PID:1786422 percent identity: 48.05; identified by sequence similarity; putative; Belongs to the transposase [...]
HI_0219 protein networkhttps://string-db.org/network/71421.HI_0219Conserved hypothetical transmembrane protein; Similar to GB:S68137 SP:P46928 PID:469476 percent identity: 84.69; identified by sequence similarity; putative.
birA protein networkhttps://string-db.org/network/71421.HI_0220.1Biotin operon repressor/biotin acetyl coenzyme A carboxylase synthetase (birA); Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA [...]
HI_0220.2 protein networkhttps://string-db.org/network/71421.HI_0220.2Predicted coding region HI0220.2; Hypothetical protein; identified by GeneMark; putative; Belongs to the uracil-DNA glycosylase (UDG) superfamily.
guaB protein networkhttps://string-db.org/network/71421.HI_0221Inosine-5'-monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo s [...]
HI_0221.1 protein networkhttps://string-db.org/network/71421.HI_0221.1Predicted coding region HI0221.1; Brute Force ORF; identified by GeneMark; putative; Belongs to the IMPDH/GMPR family.
guaA protein networkhttps://string-db.org/network/71421.HI_0222GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP.
HI_0223 protein networkhttps://string-db.org/network/71421.HI_0223rarD protein, putative; Similar to SP:P27844 percent identity: 25.08; identified by sequence similarity; putative.
HI_0224 protein networkhttps://string-db.org/network/71421.HI_0224Transcriptional regulator, putative; Similar to SP:P55658 PID:2182633 percent identity: 38.19; identified by sequence similarity; putative.
nhaA protein networkhttps://string-db.org/network/71421.HI_0225Na+/H+ antiporter (nhaA); Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
brnQ protein networkhttps://string-db.org/network/71421.HI_0226Branched chain amino acid transport system II carrier protein (brnQ); Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine) Which is coupled to a proto [...]
HI_0227 protein networkhttps://string-db.org/network/71421.HI_0227Conserved hypothetical protein; Similar to SP:P37673 PID:466714 GB:U00096 PID:1790001 percent identity: 31.37; identified by sequence similarity; putative; Belongs to the TabA/YhcH/YiaL family.
HI_0228 protein networkhttps://string-db.org/network/71421.HI_0228Predicted coding region HI0228; Hypothetical protein; identified by GeneMark; putative.
pnp protein networkhttps://string-db.org/network/71421.HI_0229Polynucleotide phosphorylase (pnp); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
nlpI protein networkhttps://string-db.org/network/71421.HI_0230Conserved hypothetical protein; May be involved in cell division.
deaD protein networkhttps://string-db.org/network/71421.HI_0231ATP-dependent RNA helicase (deaD); DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
mltF protein networkhttps://string-db.org/network/71421.HI_0232Conserved hypothetical protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromur [...]
HI_0233 protein networkhttps://string-db.org/network/71421.HI_0233Predicted coding region HI0233; Hypothetical protein; identified by GeneMark; putative.
HI_0234 protein networkhttps://string-db.org/network/71421.HI_0234Predicted coding region HI0234; Hypothetical protein; identified by GeneMark; putative.
arfA protein networkhttps://string-db.org/network/71421.HI_0235Conserved hypothetical protein; Rescues ribosomes stalled at the 3' end of non-stop mRNAs. Recruits release factor 2 (RF2) to the stalled ribosome, helping position it correctly in the ribosomal [...]
arsC protein networkhttps://string-db.org/network/71421.HI_0236Arsenate reductase, putative; Reduction of arsenate [As(V)] to arsenite [As(III)]. Belongs to the ArsC family.
secF protein networkhttps://string-db.org/network/71421.HI_0239Protein-export membrane protein (secF); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete [...]
secD protein networkhttps://string-db.org/network/71421.HI_0240Protein-export membrane protein (secD); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete [...]
yajC protein networkhttps://string-db.org/network/71421.HI_0241Conserved hypothetical protein; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes [...]
HI_0242 protein networkhttps://string-db.org/network/71421.HI_0242Conserved hypothetical protein; Similar to GB:L77117 SP:Q58397 PID:1591652 percent identity: 35.71; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family.
HI_0243 protein networkhttps://string-db.org/network/71421.HI_0243Predicted coding region HI0243; Hypothetical protein; identified by GeneMark; putative.
tgt protein networkhttps://string-db.org/network/71421.HI_0244tRNA-guanine transglycosylase (tgt); Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position [...]
queA protein networkhttps://string-db.org/network/71421.HI_0245Queuosine biosynthesis protein (queA); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
HI_0246 protein networkhttps://string-db.org/network/71421.HI_0246Predicted coding region HI0246; Hypothetical protein; identified by GeneMark; putative.
uvrA protein networkhttps://string-db.org/network/71421.HI_0249Excinuclease ABC, subunit A (uvrA); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex com [...]
ssb protein networkhttps://string-db.org/network/71421.HI_0250Single-stranded DNA binding protein (ssb); Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites [...]
tonB protein networkhttps://string-db.org/network/71421.HI_0251tonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to t [...]
exbD protein networkhttps://string-db.org/network/71421.HI_0252Biopolymer transport protein (exbD); Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
exbB protein networkhttps://string-db.org/network/71421.HI_0253Biopolymer transport protein (exbB); Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally st [...]
bcp protein networkhttps://string-db.org/network/71421.HI_0254Bacterioferritin comigratory protein (bcp); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a rol [...]
dapA protein networkhttps://string-db.org/network/71421.HI_0255Dihydrodipicolinate synthetase (dapA); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
HI_0256 protein networkhttps://string-db.org/network/71421.HI_0256Lipoprotein, putative; Similar to SP:P21167 PID:147409 PID:42126 GB:U00096 PID:1788822 percent identity: 28.37; identified by sequence similarity; putative.
yfiA protein networkhttps://string-db.org/network/71421.HI_0257Sigma(54) modulation protein, putative; During stationary phase, prevents 70S dimer formation, probably in order to regulate translation efficiency during transition between the exponential and t [...]
HI_0258 protein networkhttps://string-db.org/network/71421.HI_0258Glycosyl transferase, putative; Similar to PID:1857120 percent identity: 38.06; identified by sequence similarity; putative; Belongs to the glycosyltransferase 8 family.
HI_0260 protein networkhttps://string-db.org/network/71421.HI_0260Conserved hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine n [...]
kdkA protein networkhttps://string-db.org/network/71421.HI_0260.1Predicted coding region HI0260.1; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position. To a lesser extent, c [...]
opsX protein networkhttps://string-db.org/network/71421.HI_0261Lipopolysaccharide biosynthesis protein, putative; Catalyzes heptose transfer to the lipopolysaccharide core. It transfers the first L-glycero-D-manno-heptose to the phosphorylated 3- deoxy-alpha [...]
hxuC protein networkhttps://string-db.org/network/71421.HI_0262Heme-hemopexin utilization protein C; Required for utilization of free heme at low concentrations. Belongs to the TonB-dependent receptor family.
hxuB protein networkhttps://string-db.org/network/71421.HI_0263Heme-hemopexin utilization protein B (hxuB); Likely functions in the release of soluble HxuA from the cell; Belongs to the TPS (TC 1.B.20) family.
hxuA protein networkhttps://string-db.org/network/71421.HI_0264Heme-hemopexin utilization protein A (hxuA); Binds heme/hemopexin complexes.
folB protein networkhttps://string-db.org/network/71421.HI_0265Dihydroneopterin aldolase, putative; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. Can use L-threo-dihydroneopterin and D-erythro-dihydroneopterin as sub [...]
plsY protein networkhttps://string-db.org/network/71421.HI_0266Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes ac [...]
narQ protein networkhttps://string-db.org/network/71421.HI_0267Nitrate/nitrite sensor protein (narQ); Probable member of a two-component regulatory system. It is not known what protein it phosphorylates and in which regulatory pathway it acts, as the narL an [...]
murB protein networkhttps://string-db.org/network/71421.HI_0268UDP-N-acetylenolpyruvoylglucosamine reductase (murB); Cell wall formation.
rpoH protein networkhttps://string-db.org/network/71421.HI_0269RNA polymerase sigma-32 factor (rpoH); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is [...]
dusC protein networkhttps://string-db.org/network/71421.HI_0270Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines [...]
djlA protein networkhttps://string-db.org/network/71421.HI_0271Conserved hypothetical protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic a [...]
pyrE protein networkhttps://string-db.org/network/71421.HI_0272Orotate phosphoribosyltransferase (pyrE); Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate ( [...]
rph protein networkhttps://string-db.org/network/71421.HI_0273Ribonuclease PH (rph); Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also ad [...]
gltX protein networkhttps://string-db.org/network/71421.HI_0274glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the accept [...]
HI_0276 protein networkhttps://string-db.org/network/71421.HI_0276Ribonuclease BN (rbn); Similar to GB:L19201 SP:P32146 PID:304990 GB:U00096 PID:1790319 percent identity: 45.06; identified by sequence similarity; putative.
HI_0277 protein networkhttps://string-db.org/network/71421.HI_0277Conserved hypothetical protein; Similar to GB:L20251 SP:P37052 PID:410154 GB:U00096 PID:1787484 percent identity: 37.16; identified by sequence similarity; putative; Belongs to the UPF0225 family [...]
HI_0278 protein networkhttps://string-db.org/network/71421.HI_0278Predicted coding region HI0278; Hypothetical protein; identified by GeneMark; putative.
HI_0279 protein networkhttps://string-db.org/network/71421.HI_0279Predicted coding region HI0279; Hypothetical protein; identified by GeneMark; putative.
udp protein networkhttps://string-db.org/network/71421.HI_0280Uridine phosphorylase (udp); Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilize [...]
HI_0281 protein networkhttps://string-db.org/network/71421.HI_0281Transport protein, putative; Similar to SP:P37643 PID:466660 GB:U00096 PID:1789941 percent identity: 55.42; identified by sequence similarity; putative.
menH protein networkhttps://string-db.org/network/71421.HI_0282Conserved hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) [...]
menD protein networkhttps://string-db.org/network/71421.HI_02832-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase/2-oxoglutarate decarboxylase (menD); Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequ [...]
menF protein networkhttps://string-db.org/network/71421.HI_0285Menaquinone-specific isochorismate synthase (menF); Catalyzes the conversion of chorismate to isochorismate.
alaA protein networkhttps://string-db.org/network/71421.HI_0286Aminotransferase; Involved in the biosynthesis of alanine.
mtr protein networkhttps://string-db.org/network/71421.HI_0287Tryptophan-specific transport protein (mtr); Involved in transporting tryptophan across the cytoplasmic membrane; Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease [...]
sdaA protein networkhttps://string-db.org/network/71421.HI_0288L-serine deaminase (sdaA); Similar to GB:M28695 SP:P16095 PID:290464 GB:U00096 PID:1736451 percent identity: 68.79; identified by sequence similarity; putative.
sdaC protein networkhttps://string-db.org/network/71421.HI_0289Serine transporter (sdaC); Involved in the import of serine into the cell. Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
HI_0290 protein networkhttps://string-db.org/network/71421.HI_0290Potassium/copper-transporting ATPase, putative; Similar to GB:AL009126 percent identity: 39.57; identified by sequence similarity; putative; Belongs to the cation transport ATPase (P-type) (TC 3. [...]
HI_0291 protein networkhttps://string-db.org/network/71421.HI_0291Predicted coding region HI0291; Hypothetical protein; identified by GeneMark; putative.
HI_0292 protein networkhttps://string-db.org/network/71421.HI_0292Mercuric ion scavenger protein (merP); Similar to GB:X73112 PID:483769 SP:Q51770 percent identity: 32.84; identified by sequence similarity; putative.
HI_0293 protein networkhttps://string-db.org/network/71421.HI_0293Transcriptional regulator, merR family, putative; Could be a copper-dependent transcriptional activator of the ATPase HI_0290.
metJ protein networkhttps://string-db.org/network/71421.HI_0294Met repressor (metJ); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs [...]
rho protein networkhttps://string-db.org/network/71421.HI_0295Transcription termination factor (rho); Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and [...]
hofD protein networkhttps://string-db.org/network/71421.HI_0296Type 4 prepilin-like protein specific leader peptidase (hopD); Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
hofC protein networkhttps://string-db.org/network/71421.HI_0297Protein transport protein; Similar to GB:M32066 SP:P22609 PID:151066 percent identity: 29.18; identified by sequence similarity; putative.
hofB protein networkhttps://string-db.org/network/71421.HI_0298Protein transport protein; Similar to GB:M32066 SP:P22608 GB:S43866 PID:151065 percent identity: 41.16; identified by sequence similarity; putative; Belongs to the GSP E family.
ppdD protein networkhttps://string-db.org/network/71421.HI_0299Prepilin peptidase dependent protein D; Similar to GB:D26562 SP:P36647 GB:L28105 PID:473777 PID:456042 percent identity: 41.54; identified by sequence similarity; putative.
ampD protein networkhttps://string-db.org/network/71421.HI_0300ampD signalling protein (ampD); Involved in cell wall peptidoglycan recycling. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of th [...]
corC protein networkhttps://string-db.org/network/71421.HI_0301Hemolysin, putative; Plays a role in the transport of magnesium and cobalt ions.
lnt protein networkhttps://string-db.org/network/71421.HI_0302Apolipoprotein N-acyltransferase (cutE); Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN [...]
rsmE protein networkhttps://string-db.org/network/71421.HI_0303Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) [...]
HI_0304 protein networkhttps://string-db.org/network/71421.HI_0304Conserved hypothetical protein; Similar to PID:882477 SP:P52049 GB:U00096 PID:1789317 percent identity: 44.57; identified by sequence similarity; putative; Belongs to the UPF0301 (AlgH) family.
HI_0305 protein networkhttps://string-db.org/network/71421.HI_0305Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
rdgC protein networkhttps://string-db.org/network/71421.HI_0306Conserved hypothetical protein; May be involved in recombination; Belongs to the RdgC family.
proC protein networkhttps://string-db.org/network/71421.HI_0307Pyrroline-5-carboxylate reductase (proC); Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
hcaT protein networkhttps://string-db.org/network/71421.HI_0308Conserved hypothetical transmembrane protein; Probable permease involved in the uptake of 3-phenylpropionic acid; Belongs to the major facilitator superfamily. Phenyl propionate permease (PPP) (T [...]
xerD protein networkhttps://string-db.org/network/71421.HI_0309Integrase/recombinase (xerD); Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to conve [...]
HI_0310 protein networkhttps://string-db.org/network/71421.HI_0310Predicted coding region HI0310; Hypothetical protein; identified by GeneMark; putative.
ruvB protein networkhttps://string-db.org/network/71421.HI_0312Holliday junction DNA helicase (ruvB); The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote stra [...]
ruvA protein networkhttps://string-db.org/network/71421.HI_0313Holliday junction DNA helicase (ruvA); The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote stra [...]
ruvC protein networkhttps://string-db.org/network/71421.HI_0314Crossover junction endodeoxyribonuclease (ruvC); Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to [...]
HI_0315 protein networkhttps://string-db.org/network/71421.HI_0315Conserved hypothetical protein; Similar to GB:D10165 SP:P24237 PID:216652 PID:42173 GB:U00096 percent identity: 75.20; identified by sequence similarity; putative.
nudB protein networkhttps://string-db.org/network/71421.HI_0316datP pyrophosphohydrolase (ntpA); Catalyzes the hydrolysis of dihydroneopterin triphosphate to dihydroneopterin monophosphate and pyrophosphate. Required for efficient folate biosynthesis. Can al [...]
aspS protein networkhttps://string-db.org/network/71421.HI_0317aspartyl-tRNA synthetase (aspS); Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the ac [...]
HI_0318 protein networkhttps://string-db.org/network/71421.HI_0318Conserved hypothetical protein; Similar to SP:P54158 PID:1256620 GB:AL009126 percent identity: 23.78; identified by sequence similarity; putative.
cmoA protein networkhttps://string-db.org/network/71421.HI_0319Conserved hypothetical protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
vapB1 protein networkhttps://string-db.org/network/71421.HI_0321Virulence associated protein B (vapB); Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of toxin VapC1 (By similarity).
vapC1 protein networkhttps://string-db.org/network/71421.HI_0322Virulence associated protein C, putative; Toxic component of a type II toxin-antitoxin (TA) system. Acts as an RNase, its toxic effect is neutralized by VapB1 antitoxin (By similarity); Belongs t [...]
gloA protein networkhttps://string-db.org/network/71421.HI_0323Lactoylglutathione lyase (gloA); Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
rnt protein networkhttps://string-db.org/network/71421.HI_0324Ribonuclease T (rnt); Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the termina [...]
HI_0325 protein networkhttps://string-db.org/network/71421.HI_0325Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 52.27; identified by sequence similarity; putative.
HI_0326 protein networkhttps://string-db.org/network/71421.HI_0326Predicted coding region HI0326; Hypothetical protein; identified by GeneMark; putative.
efp protein networkhttps://string-db.org/network/71421.HI_0328Elongation factor P (efp); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possib [...]
epmB protein networkhttps://string-db.org/network/71421.HI_0329Conserved hypothetical protein; With EpmA is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. EpmB appears to ac [...]
oapA protein networkhttps://string-db.org/network/71421.HI_0330Opacity associated protein (oapA); Cell envelope protein involved in phase variation, confers opaque colony phenotype; Belongs to the OapA family.
oapB protein networkhttps://string-db.org/network/71421.HI_0331Opacity associated protein (oapB); Similar to GB:L42023 SP:P44416 PID:1003553 PID:1222256 PID:595943 percent identity: 100.00; identified by sequence similarity; putative.
recO protein networkhttps://string-db.org/network/71421.HI_0332DNA repair protein (recO); Involved in DNA repair and RecF pathway recombination.
rlmD protein networkhttps://string-db.org/network/71421.HI_0333RNA methyltransferase, putative; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U [...]
relA protein networkhttps://string-db.org/network/71421.HI_0334GTP pyrophosphokinase (relA); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response [...]
dgkA protein networkhttps://string-db.org/network/71421.HI_0335Diacylglycerol kinase (dgkA); Recycling of diacylglycerol produced during the turnover of membrane phospholipid.
mog protein networkhttps://string-db.org/network/71421.HI_0336Molybdopeterin biosynthesis protein (mog); Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor.
glnB protein networkhttps://string-db.org/network/71421.HI_0337Nitrogen regulatory protein P-II (glnB); P-II indirectly controls the transcription of the glutamine synthetase gene (GlnA). P-II prevents NR-II-catalyzed conversion of NR- I to NR-I-phosphate, t [...]
HI_0338 protein networkhttps://string-db.org/network/71421.HI_0338Conserved hypothetical transmembrane protein; Similar to GB:U00096 PID:1787885 percent identity: 42.60; identified by sequence similarity; putative.
priA protein networkhttps://string-db.org/network/71421.HI_0339Primosomal protein N' (priA); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, v [...]
trmB protein networkhttps://string-db.org/network/71421.HI_0340Conserved hypothetical protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
HI_0341 protein networkhttps://string-db.org/network/71421.HI_0341Conserved hypothetical protein; Similar to SP:P38521 PID:882488 GB:U00096 PID:1789329 percent identity: 55.65; identified by sequence similarity; putative; To E.coli YggL.
napF protein networkhttps://string-db.org/network/71421.HI_0342Ferredoxin-type protein (napF); Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF [...]
napD protein networkhttps://string-db.org/network/71421.HI_0343napD protein (napD); Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing pr [...]
napG protein networkhttps://string-db.org/network/71421.HI_0345Ferredoxin-type protein (napG); Required for electron transfer from ubiquinol, via NapC, to the periplasmic nitrate reductase NapAB complex.
napH protein networkhttps://string-db.org/network/71421.HI_0346Ferredoxin-type protein (napH); Required for electron transfer from ubiquinol, via NapC, to the periplasmic nitrate reductase NapAB complex.
napB protein networkhttps://string-db.org/network/71421.HI_0347Periplasmic nitrate reductase (napB); Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type NapC protein and [...]
napC protein networkhttps://string-db.org/network/71421.HI_0348Cytochrome C-type protein (napC); Mediates electron flow from quinones to the NapAB complex.
adk protein networkhttps://string-db.org/network/71421.HI_0349Adenylate kinase (adk); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide met [...]
HI_0350 protein networkhttps://string-db.org/network/71421.HI_0350Permease, putative; Similar to GB:U00096 SP:P36670 PID:1773117 PID:1786636 PID:563855 percent identity: 38.06; identified by sequence similarity; putative.
galE protein networkhttps://string-db.org/network/71421.HI_0351UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient r [...]
HI_0352 protein networkhttps://string-db.org/network/71421.HI_0352Conserved hypothetical protein; Similar to SP:P24324 GB:X57315 PID:43588 percent identity: 98.23; identified by sequence similarity; putative.
HI_0354 protein networkhttps://string-db.org/network/71421.HI_0354ABC transporter, ATP-binding protein; Similar to PID:1184189 GB:U00096 SP:Q47538 PID:1384059 PID:1657561 percent identity: 41.09; identified by sequence similarity; putative; Belongs to the ABC t [...]
HI_0355 protein networkhttps://string-db.org/network/71421.HI_0355ABC transporter, permease protein; Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane; Belongs to the b [...]
HI_0357 protein networkhttps://string-db.org/network/71421.HI_0357Thiamine biosynthesis protein, putative; Probably involved in thiamine biosynthesis.
HI_0358 protein networkhttps://string-db.org/network/71421.HI_0358Transcriptional activator, putative; Similar to GB:AE000511 PID:2314455 percent identity: 34.29; identified by sequence similarity; putative; Belongs to the thiaminase-2 family.
HI_0359 protein networkhttps://string-db.org/network/71421.HI_0359Iron (chelated) ABC transporter, permease protein (yfeD); Part of an ATP-driven transport system HI_0359/HI_0360/HI_0361/HI_0362 for iron; Belongs to the ABC-3 integral membrane protein family.
HI_0360 protein networkhttps://string-db.org/network/71421.HI_0360Iron (chelated) ABC transporter, permease protein (yfeC); Part of an ATP-driven transport system HI_0359/HI_0360/HI_0361/HI_0362 for iron; Belongs to the ABC-3 integral membrane protein family.
HI_0361 protein networkhttps://string-db.org/network/71421.HI_0361Iron (chelated) transporter, ATP-binding protein (yfeB); Part of an ATP-driven transport system HI_0359/HI_0360/HI_0361/HI_0362 for iron. Probably responsible for energy coupling to the transport [...]
HI_0362 protein networkhttps://string-db.org/network/71421.HI_0362Iron (chelated) ABC transporter, periplasmic-binding protein (yfeA); Part of an ATP-driven transport system HI_0359/HI_0360/HI_0361/HI_0362 for iron. Metal-binding component (Potential); Belongs [...]
pbpG protein networkhttps://string-db.org/network/71421.HI_0364Penicillin-binding protein 7, putative; Cell wall formation. May play a specialized role in remodeling the cell wall. Specifically hydrolyzes the DD- diaminopimelate-alanine bonds in high-molecul [...]
rlmN protein networkhttps://string-db.org/network/71421.HI_0365Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proo [...]
HI_0366 protein networkhttps://string-db.org/network/71421.HI_0366Fimbrial biogenesis and twitching motility protein, putative; Similar to PID:1162960 percent identity: 33.59; identified by sequence similarity; putative.
HI_0367 protein networkhttps://string-db.org/network/71421.HI_0367Conserved hypothetical protein; Similar to SP:P27434 GB:D21149 GB:U02965 GB:X64451 PID:41541 percent identity: 26.33; identified by sequence similarity; putative.
ispG protein networkhttps://string-db.org/network/71421.HI_0368gcpE protein (gcpE); Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
hisS protein networkhttps://string-db.org/network/71421.HI_0369histidyl-tRNA synthetase (hisS); Similar to GB:M11843 SP:P04804 PID:146372 GB:U00096 PID:1788861 percent identity: 66.82; identified by sequence similarity; putative.
HI_0370 protein networkhttps://string-db.org/network/71421.HI_0370Conserved hypothetical protein; Similar to GB:U00096 PID:1788860 percent identity: 36.50; identified by sequence similarity; putative.
iscX protein networkhttps://string-db.org/network/71421.HI_0371Conserved hypothetical protein; May function as iron donor in the assembly of iron-sulfur clusters.
fdx protein networkhttps://string-db.org/network/71421.HI_0372Ferredoxin (fdx-1); Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions; Belongs to the adrenodoxin/putidaredoxin family.
hscA protein networkhttps://string-db.org/network/71421.HI_0373Heat shock protein (hscA); Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB (By similarit [...]
HI_0374 protein networkhttps://string-db.org/network/71421.HI_0374Predicted coding region HI0374; Hypothetical protein; identified by GeneMark; putative; To E.coli YbfG.
hscB protein networkhttps://string-db.org/network/71421.HI_0375Conserved hypothetical protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity); Belo [...]
iscA protein networkhttps://string-db.org/network/71421.HI_0376Conserved hypothetical protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catal [...]
iscU protein networkhttps://string-db.org/network/71421.HI_0377iscU protein (iscU); A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the rol [...]
iscS protein networkhttps://string-db.org/network/71421.HI_0378nifS protein (nifS); Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental s [...]
HI_0379 protein networkhttps://string-db.org/network/71421.HI_0379Conserved hypothetical protein; Similar to GB:U00096 PID:1788880 percent identity: 63.38; identified by sequence similarity; putative.
HI_0380 protein networkhttps://string-db.org/network/71421.HI_0380Conserved hypothetical protein; Similar to GB:U00096 PID:1788881 percent identity: 54.43; identified by sequence similarity; putative; Belongs to the class IV-like SAM-binding methyltransferase s [...]
pal protein networkhttps://string-db.org/network/71421.HI_0381Peptidoglycan-associated outer membrane lipoprotein (pal); Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining oute [...]
tolB protein networkhttps://string-db.org/network/71421.HI_0382Colicin tolerance protein (tolB); Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
tolA protein networkhttps://string-db.org/network/71421.HI_0383Outer membrane integrity protein (tolA); Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integri [...]
tolR protein networkhttps://string-db.org/network/71421.HI_0384Colicin transport protein (tolR); Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
tolQ protein networkhttps://string-db.org/network/71421.HI_0385Colicin transport protein (tolQ); Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
ybgC protein networkhttps://string-db.org/network/71421.HI_0386Conserved hypothetical protein; Displays acyl-CoA thioesterase activity with short chain aliphatic acyl-CoA thioesters, such as propionyl-CoA and butyryl-CoA. Enzyme activity is relatively low, s [...]
HI_0387 protein networkhttps://string-db.org/network/71421.HI_0387ATP-dependent helicase (dinG); Similar to GB:U00096 PID:1736441 PID:1736447 PID:1788110 percent identity: 61.17; identified by sequence similarity; putative; Belongs to the helicase family. DinG [...]
tsaB protein networkhttps://string-db.org/network/71421.HI_0388Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the [...]
HI_0389 protein networkhttps://string-db.org/network/71421.HI_0389Outer membrane protein; Similar to GB:U00039 SP:P37194 GB:L23635 PID:387932 PID:466643 percent identity: 27.33; identified by sequence similarity; putative.
rnd protein networkhttps://string-db.org/network/71421.HI_0390Ribonuclease D (rnd); Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to [...]
fadD protein networkhttps://string-db.org/network/71421.HI_0390.1Long chain fatty acid coenzyme A ligase (fadD); Catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subseque [...]
HI_0391 protein networkhttps://string-db.org/network/71421.HI_0391Predicted coding region HI0391; Hypothetical protein; identified by GeneMark; putative.
HI_0392 protein networkhttps://string-db.org/network/71421.HI_0392O-antigen acetylase, putative; Similar to GP:1518853 percent identity: 31.46; identified by sequence similarity; putative.
ychF protein networkhttps://string-db.org/network/71421.HI_0393Conserved hypothetical GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner (By similarity). Does not hydrolyze GTP; Be [...]
pth protein networkhttps://string-db.org/network/71421.HI_0394peptidyl-tRNA hydrolase (pth); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
HI_0395 protein networkhttps://string-db.org/network/71421.HI_0395Conserved hypothetical protein; Similar to PID:1033114 SP:P52119 GB:U00096 PID:1788971 percent identity: 55.32; identified by sequence similarity; putative; Belongs to the UPF0125 (RnfH) family.
HI_0396 protein networkhttps://string-db.org/network/71421.HI_0396Conserved hypothetical protein; Oxygenase that catalyzes the hydroxylation of a ribosomal protein; Belongs to the ROX family.
xseA protein networkhttps://string-db.org/network/71421.HI_0397Exodeoxyribonuclease VII, large subunit (xseA); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble o [...]
nudF protein networkhttps://string-db.org/network/71421.HI_0398Conserved hypothetical protein; Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeo [...]
cpdA protein networkhttps://string-db.org/network/71421.HI_0399lacZ expression regulator (icc); Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. [...]
HI_0400 protein networkhttps://string-db.org/network/71421.HI_0400Conserved hypothetical protein; Similar to GB:U00096 PID:1788685 percent identity: 42.42; identified by sequence similarity; putative; Belongs to the UPF0381 family.
ompP1 protein networkhttps://string-db.org/network/71421.HI_0401Long-chain fatty acid transport protein (fadL); Similar to GB:M60607 SP:P10384 GB:Y00552 PID:145910 PID:41372 percent identity: 42.79; identified by sequence similarity; putative.
ogt protein networkhttps://string-db.org/network/71421.HI_0402methylated-DNA--protein-cysteine methyltransferase (dat1); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repai [...]
mutH protein networkhttps://string-db.org/network/71421.HI_0403DNA mismatch repair protein (mutH); Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family.
tilS protein networkhttps://string-db.org/network/71421.HI_0404Cell cycle protein (mesJ); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is con [...]
pdxY protein networkhttps://string-db.org/network/71421.HI_0405Pyridoxine kinase, putative; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.
accA protein networkhttps://string-db.org/network/71421.HI_0406acetyl-CoA carboxylase, carboxyl transferase (accA); Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier p [...]
znuB protein networkhttps://string-db.org/network/71421.HI_0407Conserved hypothetical integral membrane protein; Involved in the high-affinity zinc uptake transport system. Belongs to the ABC-3 integral membrane protein family.
znuC protein networkhttps://string-db.org/network/71421.HI_0408ABC transporter, ATP-binding protein (yebM); Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transp [...]
HI_0409 protein networkhttps://string-db.org/network/71421.HI_0409Conserved hypothetical protein; Similar to GB:M77039 SP:P24204 PID:146890 PID:1054957 GB:U00096 percent identity: 49.26; identified by sequence similarity; putative; In the central section; belon [...]
tyrR protein networkhttps://string-db.org/network/71421.HI_0410Transcriptional regulatory protein (tyrR); Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport.
hfq protein networkhttps://string-db.org/network/71421.HI_0411Host factor-I protein (hfq); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and c [...]
rluC protein networkhttps://string-db.org/network/71421.HI_0412Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family.
rne protein networkhttps://string-db.org/network/71421.HI_0413Ribonuclease E (rne); Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degra [...]
HI_0414 protein networkhttps://string-db.org/network/71421.HI_0414Predicted coding region HI0414; Hypothetical protein; identified by GeneMark; putative; Belongs to the opacity porin family.
thiM protein networkhttps://string-db.org/network/71421.HI_0415Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
thiD protein networkhttps://string-db.org/network/71421.HI_0416Phosphomethylpyrimidine kinase (thiD); Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.
thiE protein networkhttps://string-db.org/network/71421.HI_0417Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine [...]
HI_0418 protein networkhttps://string-db.org/network/71421.HI_0418Transport protein, putative; Similar to GB:L42023 SP:P44610 PID:1003458 PID:1222206 PID:1204537 percent identity: 60.92; identified by sequence similarity; putative.
HI_0419 protein networkhttps://string-db.org/network/71421.HI_0419Protease, putative; Similar to GB:U00096 SP:P76403 PID:1736789 PID:1736801 PID:1788397 percent identity: 79.52; identified by sequence similarity; putative; Belongs to the peptidase U32 family.
HI_0420 protein networkhttps://string-db.org/network/71421.HI_0420Predicted coding region HI0420; Hypothetical protein; identified by GeneMark; putative.
srmB protein networkhttps://string-db.org/network/71421.HI_0422ATP-dependent RNA helicase (srmB); DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activit [...]
HI_0423 protein networkhttps://string-db.org/network/71421.HI_0423Conserved hypothetical protein; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
HI_0424 protein networkhttps://string-db.org/network/71421.HI_0424rRNA methylase, putative; Similar to SP:P33635 GB:U00096 PID:1788935 percent identity: 43.03; identified by sequence similarity; putative; Belongs to the class IV-like SAM-binding methyltransfera [...]
pssA protein networkhttps://string-db.org/network/71421.HI_0425Phosphatidylserine synthase (pssA); Similar to GB:M58699 SP:P23830 PID:147389 GB:U00096 PID:1788940 percent identity: 50.33; identified by sequence similarity; putative.
fadR protein networkhttps://string-db.org/network/71421.HI_0426Fatty acid metabolism regulator protein (fadR); Multifunctional regulator of fatty acid metabolism.
nhaB protein networkhttps://string-db.org/network/71421.HI_0427Na+/H+ antiporter (nhaB); Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
dsbB protein networkhttps://string-db.org/network/71421.HI_0428Disulfide bond formation protein B (dsbB); Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
glmS protein networkhttps://string-db.org/network/71421.HI_0429Glucosamine--fructose-6-phosphate aminotransferase (glmS); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
hup protein networkhttps://string-db.org/network/71421.HI_0430DNA-binding protein HU-alpha (hupA); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [...]
HI_0431 protein networkhttps://string-db.org/network/71421.HI_0431Conserved hypothetical protein; Similar to SP:P32680 PID:396338 GB:U00096 PID:1790432 percent identity: 54.59; identified by sequence similarity; putative; To E.coli YjaG.
nudC protein networkhttps://string-db.org/network/71421.HI_0432Conserved hypothetical protein; Similar to SP:P32664 PID:396335 GB:U00096 PID:1790429 percent identity: 47.29; identified by sequence similarity; putative.
nfuA protein networkhttps://string-db.org/network/71421.HI_0433orfG protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also a [...]
comF protein networkhttps://string-db.org/network/71421.HI_0434Competence protein F (comF); Involved in transformation (competence for DNA uptake).
comE protein networkhttps://string-db.org/network/71421.HI_0435Competence protein E (comE); Involved in transformation (competence for DNA uptake); Belongs to the bacterial secretin family. PilQ subfamily.
comD protein networkhttps://string-db.org/network/71421.HI_0436Competence protein D (comD); Involved in transformation (competence for DNA uptake).
comC protein networkhttps://string-db.org/network/71421.HI_0437Competence protein C (comC); Involved in transformation (competence for DNA uptake).
comB protein networkhttps://string-db.org/network/71421.HI_0438Competence protein B (comB); Involved in transformation (competence for DNA uptake).
comA protein networkhttps://string-db.org/network/71421.HI_0439Competence protein A (comA); Involved in transformation (competence for DNA uptake).
mrcA protein networkhttps://string-db.org/network/71421.HI_0440Penicillin-binding protein 1A (ponA); Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-termina [...]
rlmJ protein networkhttps://string-db.org/network/71421.HI_0441orfJ protein; Specifically methylates the adenine in position 2030 of 23S rRNA.
HI_0442 protein networkhttps://string-db.org/network/71421.HI_0442Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
recR protein networkhttps://string-db.org/network/71421.HI_0443Recombination protein (recR); May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
topB protein networkhttps://string-db.org/network/71421.HI_0444DNA topoisomerase III (topB); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one s [...]
secG protein networkhttps://string-db.org/network/71421.HI_0445Protein-export membrane protein (secG); Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family.
fruA protein networkhttps://string-db.org/network/71421.HI_0446PTS system, fructose-specific IIBC component (fruA); The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the pho [...]
fruK protein networkhttps://string-db.org/network/71421.HI_04471-phosphofructokinase (fruK); Similar to SP:P23539 GB:X53948 PID:405894 PID:41487 GB:U00096 percent identity: 55.41; identified by sequence similarity; putative; Belongs to the carbohydrate kinas [...]
fruB protein networkhttps://string-db.org/network/71421.HI_0448PTS system, fructose-specific IIA/FPr component (fruB); The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the [...]
HI_0449 protein networkhttps://string-db.org/network/71421.HI_0449Predicted coding region HI0449; Hypothetical protein; identified by GeneMark; putative.
vapD protein networkhttps://string-db.org/network/71421.HI_0450Virulence associated protein D (vapD); Cleaves ssRNA, mostly between U:A; Belongs to the VapD ribonuclease family.
HI_0451 protein networkhttps://string-db.org/network/71421.HI_0451Conserved hypothetical protein; Similar to PID:1196479 percent identity: 56.67; identified by sequence similarity; putative.
HI_0452 protein networkhttps://string-db.org/network/71421.HI_0452Conserved hypothetical protein; Similar to GB:U14003 SP:P39319 PID:537059 GB:U00096 PID:1790664 percent identity: 52.57; identified by sequence similarity; putative.
HI_0453 protein networkhttps://string-db.org/network/71421.HI_0453Conserved hypothetical protein; Similar to GB:AE000511 PID:2313105 percent identity: 41.52; identified by sequence similarity; putative.
HI_0454 protein networkhttps://string-db.org/network/71421.HI_0454Conserved hypothetical protein; Similar to SP:P37346 GB:U00096 PID:1787342 percent identity: 59.92; identified by sequence similarity; putative.
holB protein networkhttps://string-db.org/network/71421.HI_0455DNA polymerase III, delta' subunit (holB); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' t [...]
tmk protein networkhttps://string-db.org/network/71421.HI_0456Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
mltG protein networkhttps://string-db.org/network/71421.HI_0457Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG [...]
surA protein networkhttps://string-db.org/network/71421.HI_0458Stationary phase survival protein SurA, putative; Chaperone involved in the folding of extracytoplasmic proteins.
pyrR protein networkhttps://string-db.org/network/71421.HI_0459Pyrimidine operon regulatory protein (pyrR); Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.
mazG protein networkhttps://string-db.org/network/71421.HI_0460mazG protein (mazG); Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed ce [...]
HI_0461 protein networkhttps://string-db.org/network/71421.HI_0461Conserved hypothetical protein; Similar to SP:P32181 percent identity: 35.64; identified by sequence similarity; putative.
lon protein networkhttps://string-db.org/network/71421.HI_0462ATP-dependent proteinase (lon); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required [...]
hemW protein networkhttps://string-db.org/network/71421.HI_0463Oxygen-independent coproporphyrinogen III oxidase, putative; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalent [...]
rpiA protein networkhttps://string-db.org/network/71421.HI_0464Ribose 5-phosphate isomerase A (rpiA); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
serA protein networkhttps://string-db.org/network/71421.HI_0465D-3-phosphoglycerate dehydrogenase (serA); Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathw [...]
HI_0466 protein networkhttps://string-db.org/network/71421.HI_0466Conserved hypothetical protein; Similar to PID:887848 GB:U00096 SP:P39179 PID:1789265 percent identity: 40.36; identified by sequence similarity; putative; To E.coli YgfZ (UP14) and B.aphidicola [...]
HI_0467 protein networkhttps://string-db.org/network/71421.HI_0467Conserved hypothetical protein; Similar to GB:L10328 SP:P23839 GB:X14235 PID:290494 PID:42721 percent identity: 64.81; identified by sequence similarity; putative; Belongs to the UPF0701 family.
hisG protein networkhttps://string-db.org/network/71421.HI_0468ATP phosphoribosyltransferase (hisG); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because t [...]
hisD protein networkhttps://string-db.org/network/71421.HI_0469Histidinol dehydrogenase (hisD); Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
hisC1 protein networkhttps://string-db.org/network/71421.HI_0470Histidinol-phosphate aminotransferase (hisC); Similar to SP:P06986 GB:U02071 GB:X03416 PID:41695 PID:41710 percent identity: 60.40; identified by sequence similarity; putative; Belongs to the cla [...]
hisB protein networkhttps://string-db.org/network/71421.HI_0471Imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase (hisB); Similar to SP:P06987 GB:X03416 PID:41696 PID:41711 GB:U00096 percent identity: 64.97; identified by sequence similarity; p [...]
hisH protein networkhttps://string-db.org/network/71421.HI_0472Amidotransferase (hisH); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part [...]
hisA protein networkhttps://string-db.org/network/71421.HI_0473Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (hisA); Similar to SP:P10371 PID:41713 GB:U00096 PID:1736702 PID:1736711 percent identity: 62.86; identified by sequence si [...]
hisF protein networkhttps://string-db.org/network/71421.HI_0474hisF cyclase (hisF); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR u [...]
hisI protein networkhttps://string-db.org/network/71421.HI_0475phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase (hisIE); Similar to SP:P06989 GB:D43637 GB:U02072 GB:X03974 PID:41700 percent identity: 61.22; identified by sequence s [...]
HI_0476 protein networkhttps://string-db.org/network/71421.HI_0476Predicted coding region HI0476; Hypothetical protein; identified by GeneMark; putative.
tyrP-A protein networkhttps://string-db.org/network/71421.HI_0477Tyrosine-specific transport protein (tyrP); Involved in transporting tyrosine across the cytoplasmic membrane; Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease sub [...]
atpC protein networkhttps://string-db.org/network/71421.HI_0478ATP synthase F1, subunit epsilon (atpC); Produces ATP from ADP in the presence of a proton gradient across the membrane.
atpD protein networkhttps://string-db.org/network/71421.HI_0479ATP synthase F1, subunit beta (atpD); Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the [...]
atpG protein networkhttps://string-db.org/network/71421.HI_0480ATP synthase F1, subunit gamma (atpG); Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity an [...]
atpA protein networkhttps://string-db.org/network/71421.HI_0481ATP synthase F1, subunit alpha (atpA); Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta ch [...]
atpH protein networkhttps://string-db.org/network/71421.HI_0482ATP synthase F1, subunit delta (atpH); F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containin [...]
atpF protein networkhttps://string-db.org/network/71421.HI_0483ATP synthase F0, subunit b (atpF); F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing th [...]
atpE protein networkhttps://string-db.org/network/71421.HI_0484ATP synthase F0, subunit c (atpE); F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing th [...]
atpB protein networkhttps://string-db.org/network/71421.HI_0485ATP synthase F0, subunit a (atpB); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
HI_0485.1 protein networkhttps://string-db.org/network/71421.HI_0485.1Predicted coding region HI0485.1; Brute Force ORF; identified by GeneMark; putative.
rsmG protein networkhttps://string-db.org/network/71421.HI_0486Glucose-inhibited division protein (gidB); Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
HI_0487 protein networkhttps://string-db.org/network/71421.HI_0487Predicted coding region HI0487; Hypothetical protein; identified by GeneMark; putative.
HI_0488 protein networkhttps://string-db.org/network/71421.HI_0488Conserved hypothetical protein; Similar to GB:U00096 PID:1789046 percent identity: 42.25; identified by sequence similarity; putative; Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph [...]
HI_0489 protein networkhttps://string-db.org/network/71421.HI_0489Conserved hypothetical protein; Similar to GB:U00096 PID:1789045 percent identity: 50.38; identified by sequence similarity; putative.
luxS protein networkhttps://string-db.org/network/71421.HI_0491Conserved hypothetical protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the [...]
HI_0493 protein networkhttps://string-db.org/network/71421.HI_0493Conserved hypothetical protein; Similar to GB:M29945 PID:1197032 percent identity: 54.00; identified by sequence similarity; putative; Belongs to the transposase IS3/IS150/IS904 family.
aphA protein networkhttps://string-db.org/network/71421.HI_0494Acid phosphatase; Dephosphorylates several organic phosphate monoesters. Also has a phosphotransferase activity catalyzing the transfer of low-energy phosphate groups from organic phosphate monoe [...]
HI_0495 protein networkhttps://string-db.org/network/71421.HI_0495Acid phosphatase; Similar to SP:P32697 GB:X86971 PID:396390 PID:806548 GB:U00096 percent identity: 45.56; identified by sequence similarity; putative.
hslV protein networkhttps://string-db.org/network/71421.HI_0496Heat shock protein (hslV); Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
hslU protein networkhttps://string-db.org/network/71421.HI_0497Heat shock protein (hslU); ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for [...]
potD-A protein networkhttps://string-db.org/network/71421.HI_0498Spermidine/putrescine ABC transporter, periplasmic-binding protein (potD); Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine. Polyamine binding [...]
ordL protein networkhttps://string-db.org/network/71421.HI_0499Oxidoreductase, putative; Similar to GB:M38433 SP:P37906 PID:1054921 PID:551780 GB:U00096 percent identity: 41.33; identified by sequence similarity; putative.
rmuC protein networkhttps://string-db.org/network/71421.HI_0500Conserved hypothetical protein; Involved in DNA recombination.
rbsD protein networkhttps://string-db.org/network/71421.HI_0501High affinity ribose transport protein (rbsD); Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
rbsA protein networkhttps://string-db.org/network/71421.HI_0502D-ribose ABC transporter, ATP-binding protein (rbsA); Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the [...]
rbsC protein networkhttps://string-db.org/network/71421.HI_0503D-ribose ABC transporter, permease protein (rbsC); Part of the ABC transporter complex RbsABC involved in ribose import. Probably responsible for the translocation of the substrate across the mem [...]
rbsB protein networkhttps://string-db.org/network/71421.HI_0504D-ribose ABC transporter, periplasmic-binding protein (rbsB); Part of the ABC transporter complex RbsABC involved in ribose import. Binds ribose.
rbsK protein networkhttps://string-db.org/network/71421.HI_0505Ribokinase (rbsK); Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides [...]
rbsR protein networkhttps://string-db.org/network/71421.HI_0506Rbs repressor (rbsR); Transcriptional repressor for the ribose rbsDACBK operon.
HI_0507 protein networkhttps://string-db.org/network/71421.HI_0507Conserved hypothetical transmembrane protein; Similar to PID:882531 SP:P52082 GB:U00096 PID:1789376 percent identity: 37.75; identified by sequence similarity; putative.
rraA protein networkhttps://string-db.org/network/71421.HI_0508S-adenosylmethionine:2-demethylmenaquinone methyltransferase (menG); Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne act [...]
menA protein networkhttps://string-db.org/network/71421.HI_05091,4-dihydroxy-2-naphthoate octaprenyltransferase (menA); Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
trmO protein networkhttps://string-db.org/network/71421.HI_0510Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase responsible for the addition of the methyl group in the formation of N6-methyl-N6-threonylcarbamoyladenosine at [...]
tehA protein networkhttps://string-db.org/network/71421.HI_0511Tellurite resistance protein (tehA); Ion channel involved in potassium tellurite resistance. Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
hindIIR protein networkhttps://string-db.org/network/71421.HI_0512Type II restriction endonuclease (HindIIR); Recognizes the double-stranded sequence GTYRAC and cleaves after Y-3.
hindIIM protein networkhttps://string-db.org/network/71421.HI_0513Modification methylase (hindIIM); This methylase recognizes the double-stranded sequence GTYRAC, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the Hind [...]
rpoC protein networkhttps://string-db.org/network/71421.HI_0514DNA-directed RNA polymerase, beta' chain (rpoC); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/71421.HI_0515DNA-directed RNA polymerase, beta chain (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplA protein networkhttps://string-db.org/network/71421.HI_0516Ribosomal protein L1 (rpL1); Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/71421.HI_0517Ribosomal protein L11 (rpL11); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
deoD protein networkhttps://string-db.org/network/71421.HI_0518Purine-nucleoside phosphorylase (deoD); Similar to PID:1732037 percent identity: 88.19; identified by sequence similarity; putative.
HI_0519 protein networkhttps://string-db.org/network/71421.HI_0519Transport protein, putative; Similar to GB:AE000511 PID:2314337 percent identity: 57.49; identified by sequence similarity; putative.
HI_0520 protein networkhttps://string-db.org/network/71421.HI_0520Conserved hypothetical protein; Similar to GB:U14003 SP:P39409 PID:537219 GB:U00096 PID:1790839 percent identity: 36.27; identified by sequence similarity; putative.
HI_0521 protein networkhttps://string-db.org/network/71421.HI_0521Conserved hypothetical protein; Similar to GB:U14003 SP:P37342 PID:537220 GB:U00096 PID:1790840 percent identity: 40.88; identified by sequence similarity; putative; To E.coli YjjI.
HI_0522 protein networkhttps://string-db.org/network/71421.HI_0522Conserved hypothetical protein; Similar to GB:D26185 SP:P37505 PID:467358 GB:AL009126 percent identity: 31.02; identified by sequence similarity; putative.
HI_0523 protein networkhttps://string-db.org/network/71421.HI_0523Conserved hypothetical protein; Similar to GB:AE000511 PID:2314449 percent identity: 36.28; identified by sequence similarity; putative; Belongs to the glycosyltransferase 9 family.
fba protein networkhttps://string-db.org/network/71421.HI_0524Fructose-bisphosphate aldolase (fba); Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisph [...]
pgk protein networkhttps://string-db.org/network/71421.HI_0525Phosphoglycerate kinase (pgk); Similar to SP:P11665 PID:41422 PID:882455 GB:U00096 PID:1789294 percent identity: 81.14; identified by sequence similarity; putative; Belongs to the phosphoglycerat [...]
HI_0526 protein networkhttps://string-db.org/network/71421.HI_0526Predicted coding region HI0526; Hypothetical protein; identified by GeneMark; putative; Belongs to the RNase T2 family.
HI_0527 protein networkhttps://string-db.org/network/71421.HI_0527Ferredoxin (fdx-2); Similar to SP:P00208 percent identity: 59.49; identified by sequence similarity; putative.
tyrP-B protein networkhttps://string-db.org/network/71421.HI_0528Tyrosine-specific transport protein (tyrP); Involved in transporting tyrosine across the cytoplasmic membrane; Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease sub [...]
tdk protein networkhttps://string-db.org/network/71421.HI_0529Thymidine kinase (tdk); Similar to SP:P23331 GB:X51523 GB:X53733 GB:X67326 PID:43047 percent identity: 68.62; identified by sequence similarity; putative.
tsaD protein networkhttps://string-db.org/network/71421.HI_0530O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involve [...]
rpsU protein networkhttps://string-db.org/network/71421.HI_0531Ribosomal protein S21 (rpS21); Similar to GB:J01687 SP:P02379 GB:V00346 PID:147754 PID:42868 percent identity: 83.10; identified by sequence similarity; putative; Belongs to the bacterial ribosom [...]
dnaG protein networkhttps://string-db.org/network/71421.HI_0532DNA primase (dnaG); RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpoD protein networkhttps://string-db.org/network/71421.HI_0533RNA polymerase sigma-70 factor (rpoD); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is [...]
aspA protein networkhttps://string-db.org/network/71421.HI_0534Aspartate ammonia-lyase (aspA); Similar to GB:U14003 SP:P04422 GB:L20944 GB:X02307 GB:X04066 percent identity: 77.85; identified by sequence similarity; putative; Belongs to the class-II fumarase [...]
ureD protein networkhttps://string-db.org/network/71421.HI_0535Urease accessory protein (ureH); Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
ureG protein networkhttps://string-db.org/network/71421.HI_0536Urease accessory protein (ureG); Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
ureF protein networkhttps://string-db.org/network/71421.HI_0537Urease accessory protein (ureF); Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
ureE protein networkhttps://string-db.org/network/71421.HI_0538Urease accessory protein (ureE); Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
ureC protein networkhttps://string-db.org/network/71421.HI_0539Urease, alpha subunit (ureC); Similar to SP:Q07397 PID:216362 percent identity: 67.25; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. Urease [...]
ureB protein networkhttps://string-db.org/network/71421.HI_0540Urease, beta subunit (ureB); Similar to GB:L03307 SP:Q03283 PID:148153 percent identity: 61.76; identified by sequence similarity; putative; Belongs to the urease beta subunit family.
ureA protein networkhttps://string-db.org/network/71421.HI_0541Urease, gamma subunit (ureA); Similar to SP:Q07399 PID:216360 percent identity: 67.00; identified by sequence similarity; putative; Belongs to the urease gamma subunit family.
groS protein networkhttps://string-db.org/network/71421.HI_0542Chaperonin (groES); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
groL protein networkhttps://string-db.org/network/71421.HI_0543Heat shock protein (groEL); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
rplI protein networkhttps://string-db.org/network/71421.HI_0544Ribosomal protein L9 (rpL9); Binds to the 23S rRNA.
rpsR protein networkhttps://string-db.org/network/71421.HI_0545Ribosomal protein S18 (rpS18); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial rib [...]
priB protein networkhttps://string-db.org/network/71421.HI_0546Primosomal replication protein N (priB); Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
rpsF protein networkhttps://string-db.org/network/71421.HI_0547Ribosomal protein S6 (rpS6); Binds together with S18 to 16S ribosomal RNA; Belongs to the bacterial ribosomal protein bS6 family.
infA protein networkhttps://string-db.org/network/71421.HI_0548Translation initiation factor 1 (infA); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethio [...]
rsmA protein networkhttps://string-db.org/network/71421.HI_0549Dimethyladenosine transferase (ksgA); Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May p [...]
lex1 protein networkhttps://string-db.org/network/71421.HI_0550Lipooligosaccharide biosynthesis protein; Involved in extracellular lipooligosaccharide (LOS) biosynthesis and virulence expression. Involved in the synthesis of the oligosaccharide moiety of the [...]
apaH protein networkhttps://string-db.org/network/71421.HI_0551Diadenosine-tetraphosphatase (apaH); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
HI_0552 protein networkhttps://string-db.org/network/71421.HI_0552Predicted coding region HI0552; Hypothetical protein; identified by GeneMark; putative.
gnd protein networkhttps://string-db.org/network/71421.HI_05536-phosphogluconate dehydrogenase, decarboxylating (gnd); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NAD [...]
HI_0554 protein networkhttps://string-db.org/network/71421.HI_0554Predicted coding region HI0554; Hypothetical protein; identified by GeneMark; putative.
HI_0555 protein networkhttps://string-db.org/network/71421.HI_0555Conserved hypothetical protein; Similar to GB:M87483 SP:Q02009 PID:551879 percent identity: 40.21; identified by sequence similarity; putative.
pgl protein networkhttps://string-db.org/network/71421.HI_0556Oxidoreductase, putative (devB); Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
HI_0557 protein networkhttps://string-db.org/network/71421.HI_0557Predicted coding region HI0557; Hypothetical protein; identified by GeneMark; putative.
zwf protein networkhttps://string-db.org/network/71421.HI_0558Glucose-6-phosphate 1-dehydrogenase (zwf); Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
cysQ protein networkhttps://string-db.org/network/71421.HI_0559Sulfite synthesis pathway protein (cysQ); Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.
HI_0559.1 protein networkhttps://string-db.org/network/71421.HI_0559.1Predicted coding region HI0559.1; Brute Force ORF; identified by GeneMark; putative.
HI_0561 protein networkhttps://string-db.org/network/71421.HI_0561Conserved hypothetical protein; Similar to GP:1655665 percent identity: 43.93; identified by sequence similarity; putative.
hslR protein networkhttps://string-db.org/network/71421.HI_0562Conserved hypothetical protein; Involved in the recycling of free 50S ribosomal subunits that still carry a nascent chain. Binds RNA more specifically than DNA. Binds with very high affinity to t [...]
asnC protein networkhttps://string-db.org/network/71421.HI_0563Transcriptional regulatory protein (asnC); Activator of asnA transcription.
asnA protein networkhttps://string-db.org/network/71421.HI_0564Aspartate--ammonia ligase (asnA); Similar to GB:L10328 SP:P00963 GB:J01657 GB:K00826 GB:M10679 percent identity: 63.33; identified by sequence similarity; putative.
gph protein networkhttps://string-db.org/network/71421.HI_0565Phosphoglycolate phosphatase (gph); Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the [...]
rpe protein networkhttps://string-db.org/network/71421.HI_0566Ribulose-phosphate 3-epimerase (dod); Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
gyrB protein networkhttps://string-db.org/network/71421.HI_0567DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromoso [...]
HI_0568 protein networkhttps://string-db.org/network/71421.HI_0568Transcription accessory protein (tex); Similar to SP:Q45388 PID:1477402 percent identity: 58.05; identified by sequence similarity; putative.
greB protein networkhttps://string-db.org/network/71421.HI_0569Transcription elongation factor (greB); Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trap [...]
HI_0570 protein networkhttps://string-db.org/network/71421.HI_0570Conserved hypothetical protein; Similar to GB:U00096 PID:1790401 percent identity: 65.70; identified by sequence similarity; putative.
oxyR protein networkhttps://string-db.org/network/71421.HI_0571Hydrogen peroxide-inducible genes activator (oxyR); Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione-reductase.
PGdx protein networkhttps://string-db.org/network/71421.HI_0572Membrane protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection again [...]
slyX protein networkhttps://string-db.org/network/71421.HI_0573slyX protein (slyX); Similar to GB:L13261 SP:P30857 PID:290468 PID:606282 GB:U00096 percent identity: 50.75; identified by sequence similarity; putative; Belongs to the SlyX family.
HI_0574 protein networkhttps://string-db.org/network/71421.HI_0574FkbP-type peptidyl-prolyl cis-trans isomerase (fkpA); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By sim [...]
HI_0575 protein networkhttps://string-db.org/network/71421.HI_0575Conserved hypothetical protein; Similar to SP:P45533 PID:606280 GB:U00096 PID:1789744 percent identity: 67.42; identified by sequence similarity; putative; To E.coli YheO.
tusD protein networkhttps://string-db.org/network/71421.HI_0576Conserved hypothetical protein; Could be part of a sulfur-relay system; Belongs to the DsrE/TusD family.
tusC protein networkhttps://string-db.org/network/71421.HI_0576.1Conserved hypothetical protein; Could be part of a sulfur-relay system; Belongs to the DsrF/TusC family.
HI_0577 protein networkhttps://string-db.org/network/71421.HI_0577Predicted coding region HI0577; Hypothetical protein; identified by GeneMark; putative.
tufA protein networkhttps://string-db.org/network/71421.HI_0578Elongation factor Tu (tufA); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
fusA protein networkhttps://string-db.org/network/71421.HI_0579Elongation factor G (fusA); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to th [...]
rpsG protein networkhttps://string-db.org/network/71421.HI_0580Ribosomal protein S7 (rpS7); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit i [...]
rpsL protein networkhttps://string-db.org/network/71421.HI_0581Ribosomal protein S12 (rps12); With S4 and S5 plays an important role in translational accuracy.
mnmG protein networkhttps://string-db.org/network/71421.HI_0582Glucose inhibited division protein (gidA); NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm [...]
cpdB protein networkhttps://string-db.org/network/71421.HI_05832',3'-cyclic-nucleotide 2'-phosphodiesterase (cpdB); This bifunctional enzyme catalyzes two consecutive reactions during ribonucleic acid degradation. Converts a 2',3'-cyclic nucleotide to a 3'-n [...]
abgA protein networkhttps://string-db.org/network/71421.HI_0584Hydrolase; Catalyzes the cleavage of p-aminobenzoyl-glutamate (PABA-GLU) to form p-aminobenzoate (PABA) and glutamate.
HI_0585 protein networkhttps://string-db.org/network/71421.HI_0585Predicted coding region HI0585; Hypothetical protein; identified by GeneMark; putative.
HI_0586 protein networkhttps://string-db.org/network/71421.HI_0586Predicted coding region HI0586; Hypothetical protein; identified by GeneMark; putative.
pepE protein networkhttps://string-db.org/network/71421.HI_0587Peptidase E (pepE); Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthe [...]
HI_0588 protein networkhttps://string-db.org/network/71421.HI_0588N-carbamyl-L-amino acid amidohydrolase; Similar to SP:P37113 GB:S67784 GB:X74289 PID:460895 SP:Q53389 percent identity: 35.94; identified by sequence similarity; putative; Belongs to the peptidas [...]
HI_0589 protein networkhttps://string-db.org/network/71421.HI_0589Sigma factor regulatory protein, putative; Similar to SP:P46187 PID:987645 PID:1045631 PID:1050877 GB:U00096 percent identity: 29.01; identified by sequence similarity; putative.
potE protein networkhttps://string-db.org/network/71421.HI_0590Putrescine-ornithine antiporter (potE); Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescin [...]
speF protein networkhttps://string-db.org/network/71421.HI_0591Ornithine decarboxylase (speF); Similar to GB:M64495 SP:P24169 PID:147331 GB:U00096 PID:1651300 percent identity: 66.43; identified by sequence similarity; putative; Belongs to the Orn/Lys/Arg de [...]
HI_0592 protein networkhttps://string-db.org/network/71421.HI_0592Predicted coding region HI0592; Hypothetical protein; identified by GeneMark; putative.
HI_0594 protein networkhttps://string-db.org/network/71421.HI_0594Conserved hypothetical transmembrane protein; Similar to GB:AE000783 percent identity: 35.02; identified by sequence similarity; putative; To B.subtilis YcgA.
arcC protein networkhttps://string-db.org/network/71421.HI_0595Carbamate kinase (arcC); Similar to SP:P13982 GB:X14693 PID:45290 percent identity: 78.32; identified by sequence similarity; putative; Belongs to the carbamate kinase family.
arcB protein networkhttps://string-db.org/network/71421.HI_0596Ornithine carbamoyltransferase (arcB); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Be [...]
HI_0597 protein networkhttps://string-db.org/network/71421.HI_0597Conserved hypothetical protein; Similar to SP:P27848 percent identity: 41.29; identified by sequence similarity; putative.
crcB protein networkhttps://string-db.org/network/71421.HI_0597.1crcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
recX protein networkhttps://string-db.org/network/71421.HI_0599Regulatory protein (recX); Modulates RecA activity; Belongs to the RecX family.
recA protein networkhttps://string-db.org/network/71421.HI_0600recA protein (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization [...]
tfoX protein networkhttps://string-db.org/network/71421.HI_0601DNA transformation protein (tfoX); Required for DNA transformation. Positively regulates genes required for DNA transformation (late competence-specific genes) in association with CRP. Required f [...]
hemY protein networkhttps://string-db.org/network/71421.HI_0602hemY protein (hemY); Involved in a late step of protoheme IX synthesis.
HI_0602.1 protein networkhttps://string-db.org/network/71421.HI_0602.1Predicted coding region HI0602.1; Brute Force ORF; identified by GeneMark; putative; To E.coli HemX C-terminal region.
HI_0603 protein networkhttps://string-db.org/network/71421.HI_0603uroporphyrin-III C-methyltransferase (hemX); Similar to GB:M87049 SP:P09127 GB:X12614 GB:X13406 PID:148202 percent identity: 40.45; identified by sequence similarity; putative; To E.coli HemX N-t [...]
cyaA protein networkhttps://string-db.org/network/71421.HI_0604Adenylate cyclase (cyaA); Plays an essential role in competence development.
gpsA protein networkhttps://string-db.org/network/71421.HI_0605Glycerol-3-phosphate dehydrogenase (NAD+) (gpsA); Similar to SP:P37606 PID:466746 GB:U00096 PID:1657692 PID:1790037 percent identity: 66.57; identified by sequence similarity; putative; Belongs t [...]
cysE protein networkhttps://string-db.org/network/71421.HI_0606Serine acetyltransferase (cysE); Similar to SP:P05796 GB:M15745 GB:M34333 PID:145676 PID:145694 percent identity: 73.05; identified by sequence similarity; putative.
sdhL protein networkhttps://string-db.org/network/71421.HI_0607Shikimate 5-dehydrogenase-related protein; In vitro, is able to catalyze the NADP(+)-dependent oxidation of shikimate to 3-dehydroshikimate. However, has much lower activity than classical shikim [...]
HI_0608 protein networkhttps://string-db.org/network/71421.HI_0608Conserved hypothetical protein; Similar to GB:L77117 SP:Q58086 PID:1591386 percent identity: 40.10; identified by sequence similarity; putative.
folD protein networkhttps://string-db.org/network/71421.HI_0609Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase (folD); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hyd [...]
fucP protein networkhttps://string-db.org/network/71421.HI_0610L-fucose permease (fucP); Transport of L-fucose into the cell; Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
fucA protein networkhttps://string-db.org/network/71421.HI_0611L-fuculose phosphate aldolase (fucA); Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosph [...]
fucU protein networkhttps://string-db.org/network/71421.HI_0612Fucose operon protein (fucU); Involved in the anomeric conversion of L-fucose.
fucK protein networkhttps://string-db.org/network/71421.HI_0613Fuculokinase (fucK); Catalyzes the phosphorylation of L-fuculose. Belongs to the FGGY kinase family.
fucI protein networkhttps://string-db.org/network/71421.HI_0614L-fucose isomerase (fucI); Converts the aldose L-fucose into the corresponding ketose L- fuculose.
fucR protein networkhttps://string-db.org/network/71421.HI_0615L-fucose operon activator (fucR); Transcriptional activator of the fuc operon.
rapA protein networkhttps://string-db.org/network/71421.HI_0616ATP-dependent helicase (hepA); Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high sal [...]
rluA protein networkhttps://string-db.org/network/71421.HI_0617Conserved hypothetical protein; Dual specificity enzyme that catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of tra [...]
glpG protein networkhttps://string-db.org/network/71421.HI_0618Glp protein, putative; Rhomboid-type serine protease that catalyzes intramembrane proteolysis; Belongs to the peptidase S54 family.
glpR protein networkhttps://string-db.org/network/71421.HI_0619Glycerol-3-phosphate regulon repressor (glpR); Repressor of the glycerol-3-phosphate regulon.
metQ protein networkhttps://string-db.org/network/71421.HI_062028 kDa outer membrane protein (hlpA); This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system; Belongs to the NlpA lipoprotein family.
metN protein networkhttps://string-db.org/network/71421.HI_0621ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
gmhB protein networkhttps://string-db.org/network/71421.HI_0621.1Conserved hypothetical protein; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C- [...]
def protein networkhttps://string-db.org/network/71421.HI_0622Polypeptide deformylase (def); Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methio [...]
fmt protein networkhttps://string-db.org/network/71421.HI_0623methionyl-tRNA formyltransferase (fmt); Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formy [...]
rsmB protein networkhttps://string-db.org/network/71421.HI_0624Sun protein (sun); Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
trkA protein networkhttps://string-db.org/network/71421.HI_0625TRK system potassium uptake protein (trkA); Part of a potassium transport system.
mscL protein networkhttps://string-db.org/network/71421.HI_0626Large conductance mechanosensitive channel (mscL); Channel that opens in response to stretch forces in the membrane lipid bilayer. Forms a nonselective ion channel with a conductance of about 4 n [...]
sdhE protein networkhttps://string-db.org/network/71421.HI_0627Conserved hypothetical protein; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogen [...]
rpoE protein networkhttps://string-db.org/network/71421.HI_0628RNA polymerase sigma-E factor (rpoE); Sigma factors are initiation factors that promote the attachment of RNA polymerase (RNAP) to specific initiation sites and are then released. Extracytoplasmi [...]
rseA protein networkhttps://string-db.org/network/71421.HI_0629sigma-E factor negative regulatory protein (mclA); An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti- [...]
rseB protein networkhttps://string-db.org/network/71421.HI_0630sigma-E factor regulatory protein (rseB); Negatively modulates the activity of sigma-E (RpoE) by stabilizing RseA under non-stress conditions. Although not essential for association of sigma-E wi [...]
coaA protein networkhttps://string-db.org/network/71421.HI_0631Pantothenate kinase (coaA); Similar to GB:M36321 SP:P15044 GB:M90071 PID:145560 PID:145561 percent identity: 64.10; identified by sequence similarity; putative.
HI_0632 protein networkhttps://string-db.org/network/71421.HI_0632Elongation factor Tu (tufB); Similar to GB:U00006 SP:P02990 GB:J01717 GB:M10459 GB:X57091 percent identity: 92.64; identified by sequence similarity; putative.
HI_0633 protein networkhttps://string-db.org/network/71421.HI_0633Predicted coding region HI0633; Hypothetical protein; identified by GeneMark; putative.
dusA protein networkhttps://string-db.org/network/71421.HI_0634Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines [...]
HI_0635 protein networkhttps://string-db.org/network/71421.HI_0635Hemoglobin-binding protein; Acts as a receptor for hemoglobin or the hemoglobin/haptoglobin complex of the human host and is required for heme uptake.
HI_0636 protein networkhttps://string-db.org/network/71421.HI_0636Conserved hypothetical protein; Similar to GB:U00096 PID:1788685 percent identity: 42.50; identified by sequence similarity; putative; Belongs to the UPF0381 family.
trpS protein networkhttps://string-db.org/network/71421.HI_0637tryptophanyl-tRNA synthetase (trpS); Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
hflD protein networkhttps://string-db.org/network/71421.HI_0638Conserved hypothetical protein; Similar to SP:P25746 PID:581207 GB:U00096 PID:1787377 percent identity: 51.21; identified by sequence similarity; putative.
purB protein networkhttps://string-db.org/network/71421.HI_0639Adenylosuccinate lyase (purB); Similar to GB:M74924 SP:P25739 PID:145203 PID:42585 GB:U00096 percent identity: 76.97; identified by sequence similarity; putative.
rplJ protein networkhttps://string-db.org/network/71421.HI_0640Ribosomal protein L10 (rpL10); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal [...]
rplL protein networkhttps://string-db.org/network/71421.HI_0641Ribosomal protein L7/L12 (rpL7/L12); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to [...]
glmU protein networkhttps://string-db.org/network/71421.HI_0642UDP-N-acetylglucosamine pyrophosphorylase (glmU); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain [...]
torZ protein networkhttps://string-db.org/network/71421.HI_0643Biotin sulfoxide reductase (bisC); Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.
torY protein networkhttps://string-db.org/network/71421.HI_0644Cytochrome C-type protein (yecK); Part of the anaerobic respiratory chain of trimethylamine-N- oxide reductase TorZ. Required for electron transfer to the TorZ terminal enzyme (By similarity).
pldB protein networkhttps://string-db.org/network/71421.HI_0645Lysophospholipase L2 (pldB); Similar to PID:1449198 percent identity: 37.83; identified by sequence similarity; putative.
asd protein networkhttps://string-db.org/network/71421.HI_0646Aspartate-semialdehyde dehydrogenase (asd); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to [...]
HI_0647 protein networkhttps://string-db.org/network/71421.HI_0647Transport protein, putative; Similar to GB:M57715 SP:P22037 PID:154179 percent identity: 42.40; identified by sequence similarity; putative.
mdaB protein networkhttps://string-db.org/network/71421.HI_0648Modulator of drug activity B (mdaB); NADPH-specific quinone reductase.
rep protein networkhttps://string-db.org/network/71421.HI_0649ATP-dependent DNA helicase (rep); Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-strand [...]
HI_0650 protein networkhttps://string-db.org/network/71421.HI_0650Predicted coding region HI0650; Hypothetical protein; identified by GeneMark; putative.
coaD protein networkhttps://string-db.org/network/71421.HI_0651Lipopolysaccharide core biosynthesis protein (kdtB); Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the ba [...]
waaA protein networkhttps://string-db.org/network/71421.HI_06523-deoxy-d-manno-octulosonic-acid transferase (kdtA); Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of a single 3-deoxy-D-manno-octulosonate (Kdo) residue from CMP-Kdo [...]
HI_0653 protein networkhttps://string-db.org/network/71421.HI_0653Lipopolysaccharide biosynthesis protein; Similar to PID:1389735 percent identity: 51.43; identified by sequence similarity; putative; Belongs to the glycosyltransferase 2 family. WaaE/KdtX subfam [...]
tag protein networkhttps://string-db.org/network/71421.HI_0654DNA-3-methyladenine glycosidase I (tagI); Hydrolysis of the deoxyribose N-glycosidic bond to excise 3- methyladenine from the damaged DNA polymer formed by alkylation lesions.
aroE protein networkhttps://string-db.org/network/71421.HI_0655Shikimate 5-dehydrogenase (aroE); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-deh [...]
tsaC protein networkhttps://string-db.org/network/71421.HI_0656Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conve [...]
HI_0656.1 protein networkhttps://string-db.org/network/71421.HI_0656.1Conserved hypothetical protein; Similar to SP:P45771 PID:606217 GB:U00096 PID:1789677 percent identity: 48.32; identified by sequence similarity; putative; To E.coli YrdD.
yheS protein networkhttps://string-db.org/network/71421.HI_0658ABC transporter, ATP-binding protein; Genetic data indicate it may be involved in ribosome assembly or function.
HI_0659 protein networkhttps://string-db.org/network/71421.HI_0659Predicted coding region HI0659; Hypothetical protein; identified by GeneMark; putative.
HI_0660 protein networkhttps://string-db.org/network/71421.HI_0660Predicted coding region HI0660; Hypothetical protein; identified by GeneMark; putative.
HI_0661 protein networkhttps://string-db.org/network/71421.HI_0661Hemoglobin-binding protein; Acts as a receptor for hemoglobin or the hemoglobin/haptoglobin complex of the human host and is required for heme uptake.
HI_0663 protein networkhttps://string-db.org/network/71421.HI_0663ATP-binding transport protein (cydD); Similar to SP:P27299 GB:Z11796 PID:42023 GB:U00096 PID:1651441 percent identity: 27.76; identified by sequence similarity; putative.
HI_0664 protein networkhttps://string-db.org/network/71421.HI_0664ABC transporter, ATP-binding protein; Similar to GB:AL009126 percent identity: 29.51; identified by sequence similarity; putative.
HI_0665 protein networkhttps://string-db.org/network/71421.HI_0665Predicted coding region HI0665; Hypothetical protein; identified by GeneMark; putative; Belongs to the HipA Ser/Thr kinase family.
HI_0666 protein networkhttps://string-db.org/network/71421.HI_0666Predicted coding region HI0666; Hypothetical protein; identified by GeneMark; putative.
HI_0666.1 protein networkhttps://string-db.org/network/71421.HI_0666.1Predicted coding region HI0666.1; Brute Force ORF; identified by GeneMark; putative.
glpX protein networkhttps://string-db.org/network/71421.HI_0667glpX protein (glpX); Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate.
zapB protein networkhttps://string-db.org/network/71421.HI_0668Conserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, s [...]
mioC protein networkhttps://string-db.org/network/71421.HI_0669mioC protein (mioC); Probable electron transporter required for biotin synthase activity; Belongs to the flavodoxin family. MioC subfamily.
dtd protein networkhttps://string-db.org/network/71421.HI_0670Conserved hypothetical protein; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischa [...]
ispF protein networkhttps://string-db.org/network/71421.HI_0671Conserved hypothetical protein; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes t [...]
ispD protein networkhttps://string-db.org/network/71421.HI_0672Conserved hypothetical protein; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
ftsB protein networkhttps://string-db.org/network/71421.HI_0673Conserved hypothetical protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division prot [...]
gpt1 protein networkhttps://string-db.org/network/71421.HI_0674Xanthine-guanine phosphoribosyltransferase (gptA); Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [...]
pepD protein networkhttps://string-db.org/network/71421.HI_0675Aminoacyl-histidine dipeptidase (pepD); Dipeptidase with broad substrate specificity.
xerC protein networkhttps://string-db.org/network/71421.HI_0676Integrase/recombinase (xerC); Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to conve [...]
HI_0677 protein networkhttps://string-db.org/network/71421.HI_0677Predicted coding region HI0677; Hypothetical protein; identified by GeneMark; putative.
tpiA protein networkhttps://string-db.org/network/71421.HI_0678Triosephosphate isomerase (tpiA); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs [...]
glpE protein networkhttps://string-db.org/network/71421.HI_0679glpE protein (glpE); Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
HI_0680 protein networkhttps://string-db.org/network/71421.HI_0680rarD protein, putative; Similar to SP:P27844 percent identity: 27.15; identified by sequence similarity; putative.
ilvY protein networkhttps://string-db.org/network/71421.HI_0681Transcriptional activator (ilvY); This protein activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate. IlvY is also a negative regulator of its own e [...]
ilvC protein networkhttps://string-db.org/network/71421.HI_0682Ketol-acid reductoisomerase (ilvC); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) [...]
glpC protein networkhttps://string-db.org/network/71421.HI_0683Anaerobic glycerol-3-phosphate dehydrogenase, subunit C (glpC); Electron transfer protein; may also function as the membrane anchor for the GlpAB dimer.
glpB protein networkhttps://string-db.org/network/71421.HI_0684Anaerobic glycerol-3-phosphate dehydrogenase, subunit B (glpB); Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor (By similarity).
glpA protein networkhttps://string-db.org/network/71421.HI_0685Anaerobic glycerol-3-phosphate dehydrogenase, subunit A (glpA); Similar to GB:M20938 SP:P13032 PID:146177 GB:U00096 PID:1788574 percent identity: 70.24; identified by sequence similarity; putativ [...]
glpT protein networkhttps://string-db.org/network/71421.HI_0686Glycerol-3-phosphatase transporter (glpT); Responsible for glycerol-3-phosphate uptake; Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
HI_0687 protein networkhttps://string-db.org/network/71421.HI_0687Conserved hypothetical protein; Similar to GB:D26185 SP:P37511 PID:467365 GB:AL009126 percent identity: 24.11; identified by sequence similarity; putative.
HI_0688 protein networkhttps://string-db.org/network/71421.HI_0688Predicted coding region HI0688; Hypothetical protein; identified by GeneMark; putative.
glpQ protein networkhttps://string-db.org/network/71421.HI_0689Glycerophosphoryl diester phosphodiesterase (glpQ); Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols. Has a specific affinity [...]
glpF protein networkhttps://string-db.org/network/71421.HI_0690Glycerol uptake facilitator protein (glpF); Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplas [...]
glpK protein networkhttps://string-db.org/network/71421.HI_0691Glycerol kinase (glpK); Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase fam [...]
HI_0692 protein networkhttps://string-db.org/network/71421.HI_0692Xanthine-guanine phosphoribosyltransferase (gptB); Similar to SP:P26972 GB:X52093 GB:X63336 PID:47695 percent identity: 74.03; identified by sequence similarity; putative.
hel protein networkhttps://string-db.org/network/71421.HI_0693Lipoprotein E (hel); Similar to GB:M68502 SP:P26093 PID:1573696 percent identity: 99.64; identified by sequence similarity; putative.
rluE protein networkhttps://string-db.org/network/71421.HI_0694Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family.
ppx protein networkhttps://string-db.org/network/71421.HI_0695Exopolyphosphatase, putative; Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain.
tamB protein networkhttps://string-db.org/network/71421.HI_0696Conserved hypothetical protein; Part of the translocation and assembly module (TAM) autotransporter assembly complex, which functions in translocation of autotransporters across the outer membran [...]
tama protein networkhttps://string-db.org/network/71421.HI_0698Conserved hypothetical protein; Part of the translocation and assembly module (TAM) autotransporter assembly complex, which functions in translocation of autotransporters across the outer membran [...]
slyD protein networkhttps://string-db.org/network/71421.HI_0699Peptidyl-prolyl cis-trans isomerase, FkbP-type (slyD); Folding helper with both chaperone and peptidyl-prolyl cis- trans isomerase (PPIase) activities. Chaperone activity prevents aggregation of [...]
rraB protein networkhttps://string-db.org/network/71421.HI_0700Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner b [...]
truD protein networkhttps://string-db.org/network/71421.HI_0701Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
surE protein networkhttps://string-db.org/network/71421.HI_0702Stationary-phase survival protein (surE); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
HI_0703 protein networkhttps://string-db.org/network/71421.HI_0703Lipoprotein B (lppB); Similar to GB:L10653 SP:P36684 PID:148929 percent identity: 72.25; identified by sequence similarity; putative.
HI_0704 protein networkhttps://string-db.org/network/71421.HI_0704Predicted coding region HI0704; Hypothetical protein; identified by GeneMark; putative.
lppB protein networkhttps://string-db.org/network/71421.HI_0706Lipoprotein; May be a virulence determinant; Belongs to the E.coli NlpD/Haemophilus LppB family.
mutS protein networkhttps://string-db.org/network/71421.HI_0707DNA mismatch repair protein (mutS); This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase a [...]
selA protein networkhttps://string-db.org/network/71421.HI_0708L-seryl-tRNA selenium transferase (selA); Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
selB protein networkhttps://string-db.org/network/71421.HI_0709Selenocysteine-specific elongation factor (selB); Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocystein [...]
relB protein networkhttps://string-db.org/network/71421.HI_0710Predicted coding region HI0710; Antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is YafQ (By similarity).
yafQ protein networkhttps://string-db.org/network/71421.HI_0711Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its cognate antitoxin is RelB (By similarity).
HI_0712 protein networkhttps://string-db.org/network/71421.HI_0712Hemoglobin-binding protein; Acts as a receptor for hemoglobin or the hemoglobin/haptoglobin complex of the human host and is required for heme uptake.
tig protein networkhttps://string-db.org/network/71421.HI_0713Trigger factor (tig); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By [...]
clpP protein networkhttps://string-db.org/network/71421.HI_0714ATP-dependent Clp protease, proteolytic subunit (clpP); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the [...]
clpX protein networkhttps://string-db.org/network/71421.HI_0715ATP-dependent Clp protease, ATP-binding subunit (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in [...]
secE protein networkhttps://string-db.org/network/71421.HI_0716Preprotein translocase SecE subunit (secE); Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocat [...]
nusG protein networkhttps://string-db.org/network/71421.HI_0717Transcription antitermination protein (nusG); Participates in transcription elongation, termination and antitermination.
mlaA protein networkhttps://string-db.org/network/71421.HI_0718Lipoprotein (vacJ); Involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inn [...]
HI_0719 protein networkhttps://string-db.org/network/71421.HI_0719Conserved hypothetical protein; Similar to GB:U14003 SP:P39330 PID:537085 GB:U00096 PID:1790691 percent identity: 73.72; identified by sequence similarity; putative.
htpX protein networkhttps://string-db.org/network/71421.HI_0720Heat shock protein (htpX); Similar to GB:M58470 SP:P23894 PID:146412 GB:U00096 PID:1736470 percent identity: 66.32; identified by sequence similarity; putative; Belongs to the peptidase M48B fami [...]
tusA protein networkhttps://string-db.org/network/71421.HI_0721Conserved hypothetical protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.
HI_0722 protein networkhttps://string-db.org/network/71421.HI_0722Conserved hypothetical protein; Similar to GB:U00096 PID:1790283 percent identity: 54.15; identified by sequence similarity; putative; Belongs to the IMPACT family.
trkH protein networkhttps://string-db.org/network/71421.HI_0723TRK system potassium uptake protein (trkH); Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA and requires TrkE for transport activity (By similarit [...]
yihI protein networkhttps://string-db.org/network/71421.HI_0724Conserved hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
HI_0725 protein networkhttps://string-db.org/network/71421.HI_0725Conserved hypothetical protein; Similar to PID:1685094 percent identity: 47.62; identified by sequence similarity; putative.
narP protein networkhttps://string-db.org/network/71421.HI_0726Nitrate/nitrite response regulator protein (narP); Could activate the expression of a formate dehydrogenase operon and could repress the transcription of the fumarate reductase (frdABCD) operon.
lysA protein networkhttps://string-db.org/network/71421.HI_0727Diaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
cyaY protein networkhttps://string-db.org/network/71421.HI_0727.1cyaY protein (cyaY); Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
recQ protein networkhttps://string-db.org/network/71421.HI_0728ATP-dependent DNA helicase (recQ); DNA helicase; Belongs to the helicase family. RecQ subfamily.
proS protein networkhttps://string-db.org/network/71421.HI_0729prolyl-tRNA synthetase (proS); Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end [...]
lptD protein networkhttps://string-db.org/network/71421.HI_0730Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
HI_0731 protein networkhttps://string-db.org/network/71421.HI_0731Predicted coding region HI0731; Hypothetical protein; identified by GeneMark; putative.
ftsP protein networkhttps://string-db.org/network/71421.HI_0733sufI protein (sufI); Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By [...]
plsC protein networkhttps://string-db.org/network/71421.HI_07341-acyl-glycerol-3-phosphate acyltransferase (plsC); Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position.
lpxH protein networkhttps://string-db.org/network/71421.HI_0735Conserved hypothetical protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at t [...]
HI_0736 protein networkhttps://string-db.org/network/71421.HI_0736Sodium-dependent transporter, putative; Putative sodium-dependent transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
HI_0737 protein networkhttps://string-db.org/network/71421.HI_0737Acetohydroxy acid synthase II, putative; Truncated acetolactase synthase; no longer catalytically active.
ilvD protein networkhttps://string-db.org/network/71421.HI_0738Dihydroxyacid dehydratase (ilvD); Similar to SP:P05791 GB:M10313 GB:K03503 GB:M32253 GB:X02413 percent identity: 76.87; identified by sequence similarity; putative; Belongs to the IlvD/Edd family [...]
ilvA protein networkhttps://string-db.org/network/71421.HI_0738.1Threonine deaminase (ilvA); Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a pro [...]
dnaE protein networkhttps://string-db.org/network/71421.HI_0739DNA polymerase III, alpha subunit (dnaE); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to [...]
HI_0740 protein networkhttps://string-db.org/network/71421.HI_0740Phosphomannomutase (yhxB); Similar to GB:M34393 SP:P18159 PID:142994 PID:2226139 GB:AL009126 percent identity: 38.72; identified by sequence similarity; putative; Belongs to the phosphohexose mut [...]
HI_0742 protein networkhttps://string-db.org/network/71421.HI_0742Predicted coding region HI0742; Hypothetical protein; identified by GeneMark; putative; To E.coli YtfG C-terminal region.
secB protein networkhttps://string-db.org/network/71421.HI_0743Protein-export protein (secB); One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor protein [...]
HI_0744 protein networkhttps://string-db.org/network/71421.HI_0744Conserved hypothetical protein; Similar to SP:P37688 PID:466749 GB:U00096 PID:1790040 percent identity: 50.74; identified by sequence similarity; putative.
ansB protein networkhttps://string-db.org/network/71421.HI_0745L-asparaginase II (ansB); Similar to GB:M34234 SP:P00805 GB:M34277 PID:145277 PID:146597 percent identity: 70.52; identified by sequence similarity; putative; Belongs to the asparaginase 1 family [...]
dcuB protein networkhttps://string-db.org/network/71421.HI_0746Anaerobic C4-dicarboxylate membrane transporter protein (dcuB); Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transport [...]
ndh protein networkhttps://string-db.org/network/71421.HI_0747NADH dehydrogenase (ndh); Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction [...]
plsB protein networkhttps://string-db.org/network/71421.HI_0748Glycerol-3-phosphate acyltransferase (plsB); Similar to SP:P00482 GB:K00127 PID:147295 PID:148102 PID:148109 percent identity: 57.21; identified by sequence similarity; putative; Belongs to the G [...]
lexA protein networkhttps://string-db.org/network/71421.HI_0749lexA repressor (lexA); Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA [...]
dapF protein networkhttps://string-db.org/network/71421.HI_0750Diaminopimelate epimerase (dapF); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential compone [...]
tpx protein networkhttps://string-db.org/network/71421.HI_0751Thiol peroxidase (tpx); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection [...]
purL protein networkhttps://string-db.org/network/71421.HI_0752Phosphoribosylformylglycinamidine synthase (purL); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycina [...]
anmK protein networkhttps://string-db.org/network/71421.HI_0753Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6 [...]
murQ protein networkhttps://string-db.org/network/71421.HI_0754Conserved hypothetical protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is al [...]
HI_0755 protein networkhttps://string-db.org/network/71421.HI_0755Conserved hypothetical protein; Similar to SP:P37691 PID:912478 GB:U00096 PID:1790043 percent identity: 41.83; identified by sequence similarity; putative; To E.coli YibQ.
HI_0756 protein networkhttps://string-db.org/network/71421.HI_0756Conserved hypothetical protein; Similar to SP:P37690 PID:466751 GB:U00096 PID:1790042 percent identity: 40.55; identified by sequence similarity; putative.
gpmA protein networkhttps://string-db.org/network/71421.HI_0757Phosphoglycerate mutase (gpmA); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
rpmE protein networkhttps://string-db.org/network/71421.HI_0758Ribosomal protein L31 (rpL31); Binds the 23S rRNA.
mutY protein networkhttps://string-db.org/network/71421.HI_0759A/G-specific adenine glycosylase (mutY); Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of [...]
HI_0760 protein networkhttps://string-db.org/network/71421.HI_0760Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic en [...]
mltC protein networkhttps://string-db.org/network/71421.HI_0761Membrane-bound lytic murein transglycosylase C (mltC); Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
HI_0762 protein networkhttps://string-db.org/network/71421.HI_0762Predicted coding region HI0762; Hypothetical protein; identified by GeneMark; putative.
nadR protein networkhttps://string-db.org/network/71421.HI_0763Transcriptional regulator (nadR); This enzyme has two activities: nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The RN kinase activity catalyzes the p [...]
ribB protein networkhttps://string-db.org/network/71421.HI_07643,4-dihydroxy-2-butanone 4-phosphate synthase (ribB); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
HI_0765 protein networkhttps://string-db.org/network/71421.HI_0765Lipooligosaccharide biosynthesis protein; Similar to GB:M37913 GB:L19441 PID:1573535 percent identity: 26.32; identified by sequence similarity; putative; Belongs to the glycosyltransferase 25 fa [...]
trmL protein networkhttps://string-db.org/network/71421.HI_0766rRNA methylase, putative; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- [...]
rsmD protein networkhttps://string-db.org/network/71421.HI_0767Conserved hypothetical protein; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.
ftsY protein networkhttps://string-db.org/network/71421.HI_0768Cell division protein (ftsY); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition p [...]
ftsE protein networkhttps://string-db.org/network/71421.HI_0769Cell division ATP-binding protein (ftsE); Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.
ftsX protein networkhttps://string-db.org/network/71421.HI_0770Cell division protein (ftsX); Part of the ABC transporter FtsEX involved in cellular division.
atoB protein networkhttps://string-db.org/network/71421.HI_0771acetyl-CoA acetyltransferase (atoB); Similar to GB:U00096 SP:P76461 PID:1736879 PID:1788554 PID:1799573 percent identity: 66.92; identified by sequence similarity; putative.
atoE protein networkhttps://string-db.org/network/71421.HI_0772Short-chain fatty acids transporter (atoE); May be responsible for the uptake of short-chain fatty acids.
atoA protein networkhttps://string-db.org/network/71421.HI_0773Acetate CoA-transferase, beta subunit (atoA); Similar to GB:U00096 SP:P76459 PID:1736877 PID:1788552 percent identity: 70.14; identified by sequence similarity; putative.
atoD protein networkhttps://string-db.org/network/71421.HI_0774Acetate CoA-transferase, alpha subunit; Similar to GB:U00096 SP:P76458 PID:1736876 PID:1788551 percent identity: 63.13; identified by sequence similarity; putative.
HI_0775 protein networkhttps://string-db.org/network/71421.HI_0775Transcriptional regulator; Similar to GB:X73124 SP:P39592 PID:413948 GB:AL009126 percent identity: 30.80; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulato [...]
rpsJ protein networkhttps://string-db.org/network/71421.HI_0776Ribosomal protein S10 (rpS10); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
rplC protein networkhttps://string-db.org/network/71421.HI_0777Ribosomal protein L3 (rpL3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rplD protein networkhttps://string-db.org/network/71421.HI_0778Ribosomal protein L4 (rpL4); One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It ma [...]
rplW protein networkhttps://string-db.org/network/71421.HI_0779Ribosomal protein L23 (rpL23); One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main [...]
rplB protein networkhttps://string-db.org/network/71421.HI_0780Ribosomal protein L2 (rpL2); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. [...]
rpsS protein networkhttps://string-db.org/network/71421.HI_0781Ribosomal protein S19 (rpS19); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplV protein networkhttps://string-db.org/network/71421.HI_0782Ribosomal protein L22 (rpL22); This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages o [...]
rpsC protein networkhttps://string-db.org/network/71421.HI_0783Ribosomal protein S3 (rpS3); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplP protein networkhttps://string-db.org/network/71421.HI_0784Ribosomal protein L16 (rpL16); Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpmC protein networkhttps://string-db.org/network/71421.HI_0785Ribosomal protein L29 (rpL29); Similar to SP:P55840 PID:1841330 percent identity: 90.48; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uL29 family.
rpsQ protein networkhttps://string-db.org/network/71421.HI_0786Ribosomal protein S17 (rpS17); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
HI_0787 protein networkhttps://string-db.org/network/71421.HI_0787Predicted coding region HI0787; Hypothetical protein; identified by GeneMark; putative.
rplN protein networkhttps://string-db.org/network/71421.HI_0788Ribosomal protein L14 (rpL14); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rplX protein networkhttps://string-db.org/network/71421.HI_0789Ribosomal protein L24 (rpL24); One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rplE protein networkhttps://string-db.org/network/71421.HI_0790Ribosomal protein L5 (rpL5); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protubera [...]
rpsN protein networkhttps://string-db.org/network/71421.HI_0791Ribosomal protein S14 (rpS14); Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to th [...]
rpsH protein networkhttps://string-db.org/network/71421.HI_0792Ribosomal protein S8 (rpS8); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs [...]
rplF protein networkhttps://string-db.org/network/71421.HI_0793Ribosomal protein L6 (rpL6); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near th [...]
rplR protein networkhttps://string-db.org/network/71421.HI_0794Ribosomal protein L18 (rpL18); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protu [...]
rpsE protein networkhttps://string-db.org/network/71421.HI_0795Ribosomal protein S5 (rpS5); With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
rpmD protein networkhttps://string-db.org/network/71421.HI_0796Ribosomal protein L30 (rpL30); Similar to GB:X01563 SP:P02430 GB:M24532 PID:42987 PID:606236 percent identity: 79.66; identified by sequence similarity; putative.
rplO protein networkhttps://string-db.org/network/71421.HI_0797Ribosomal protein L15 (rpL15); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
secY protein networkhttps://string-db.org/network/71421.HI_0798Preprotein translocase SecY subunit (secY); The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral ga [...]
rpmJ protein networkhttps://string-db.org/network/71421.HI_0798.1Ribosomal protein L36 (rpL36); Similar to SP:P21194 GB:M12432 PID:42990 PID:606233 PID:1128970 percent identity: 84.21; identified by sequence similarity; putative; Belongs to the bacterial ribos [...]
rpsM protein networkhttps://string-db.org/network/71421.HI_0799Ribosomal protein S13 (rpS13); Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protei [...]
rpsK protein networkhttps://string-db.org/network/71421.HI_0800Ribosomal protein S11 (rpS11); Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; B [...]
rpsD protein networkhttps://string-db.org/network/71421.HI_0801Ribosomal protein S4 (rpS4); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpoA protein networkhttps://string-db.org/network/71421.HI_0802DNA-directed RNA polymerase, alpha chain (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplQ protein networkhttps://string-db.org/network/71421.HI_0803Ribosomal protein L17 (rplQ); Similar to GB:J01685 SP:P02416 GB:X00766 PID:147716 PID:42800 percent identity: 89.76; identified by sequence similarity; putative.
HI_0804 protein networkhttps://string-db.org/network/71421.HI_0804Predicted coding region HI0804; Hypothetical protein; identified by GeneMark; putative.
HI_0806 protein networkhttps://string-db.org/network/71421.HI_0806Conserved hypothetical protein; Similar to GB:L77117 SP:Q57883 PID:1591145 percent identity: 26.80; identified by sequence similarity; putative.
dxr protein networkhttps://string-db.org/network/71421.HI_0807Conserved hypothetical protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR [...]
frr protein networkhttps://string-db.org/network/71421.HI_0808Ribosome releasing factor (rrf); Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ri [...]
pckA protein networkhttps://string-db.org/network/71421.HI_0809Phosphoenolpyruvate carboxykinase (pckA); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between t [...]
hslO protein networkhttps://string-db.org/network/71421.HI_0810Conserved hypothetical protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in t [...]
argH protein networkhttps://string-db.org/network/71421.HI_0811Argininosuccinate lyase (argH); Similar to SP:P11447 GB:J01590 GB:M21446 PID:145335 PID:396307 percent identity: 73.52; identified by sequence similarity; putative.
galU protein networkhttps://string-db.org/network/71421.HI_0812Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family.
csrA protein networkhttps://string-db.org/network/71421.HI_0813Carbon storage regulator (csrA); A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from [...]
alaS protein networkhttps://string-db.org/network/71421.HI_0814alanyl-tRNA synthetase (alaS); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end [...]
uspA protein networkhttps://string-db.org/network/71421.HI_0815Universal stress protein A (uspA); Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.
pepP protein networkhttps://string-db.org/network/71421.HI_0816Aminopeptidase P (pepP); Similar to GB:D00398 SP:P15034 PID:216529 PID:216627 PID:882438 percent identity: 54.59; identified by sequence similarity; putative.
HI_0817 protein networkhttps://string-db.org/network/71421.HI_0817Conserved hypothetical protein; Similar to GB:D90281 SP:P25533 PID:216626 PID:882439 GB:U00096 percent identity: 46.41; identified by sequence similarity; putative; Belongs to the UPF0149 family.
galM protein networkhttps://string-db.org/network/71421.HI_0818Aldose 1-epimerase (galM); Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity).
galK protein networkhttps://string-db.org/network/71421.HI_0819Galactokinase (galK); Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
galT protein networkhttps://string-db.org/network/71421.HI_0820Galactose-1-phosphate uridylyltransferase (galT); Similar to SP:P31764 GB:X65934 PID:1573833 percent identity: 99.14; identified by sequence similarity; putative.
galR protein networkhttps://string-db.org/network/71421.HI_0821Galactose operon repressor (galR); Repressor of the galactose operon. Binds galactose as an inducer.
mglB protein networkhttps://string-db.org/network/71421.HI_0822Galactose ABC transporter, periplasmic-binding protein (mglB); This protein is involved in the active transport of galactose and glucose.
mglA protein networkhttps://string-db.org/network/71421.HI_0823Galactoside ABC transporter, ATP-binding protein (mglA); Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transpo [...]
mglC protein networkhttps://string-db.org/network/71421.HI_0824Galactoside ABC transporter, permease protein (mglC); Part of the binding-protein-dependent transport system for galactoside. Probably responsible for the translocation of the substrate across th [...]
HI_0825 protein networkhttps://string-db.org/network/71421.HI_0825Predicted coding region HI0825; Hypothetical protein; identified by GeneMark; putative.
HI_0826 protein networkhttps://string-db.org/network/71421.HI_0826Conserved hypothetical transmembrane protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
HI_0827 protein networkhttps://string-db.org/network/71421.HI_0827Conserved hypothetical; Similar to GB:K00431 SP:P04379 PID:455187 PID:902382 PID:902391 percent identity: 69.35; identified by sequence similarity; putative; Belongs to the acyl coenzyme A hydrol [...]
HI_0828 protein networkhttps://string-db.org/network/71421.HI_0828Conserved hypothetical protein; Similar to SP:P31070 percent identity: 67.35; identified by sequence similarity; putative.
slt protein networkhttps://string-db.org/network/71421.HI_0829Soluble lytic murein transglycosylase, putative; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division (By similarity).
trpR protein networkhttps://string-db.org/network/71421.HI_0830Trp operon repressor (trpR); This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription (By sim [...]
mtgA protein networkhttps://string-db.org/network/71421.HI_0831Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 fam [...]
frdD protein networkhttps://string-db.org/network/71421.HI_0832Fumarate reductase, 13 kDa hydrophobic protein (frdD); Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
frdC protein networkhttps://string-db.org/network/71421.HI_0833Fumarate reductase, 15 kDa hydrophobic protein (frdC); Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
frdB protein networkhttps://string-db.org/network/71421.HI_0834Fumarate reductase, iron-sulfur protein (frdB); Similar to GB:U14003 SP:P00364 GB:J01611 PID:145264 PID:536997 percent identity: 75.51; identified by sequence similarity; putative.
frdA protein networkhttps://string-db.org/network/71421.HI_0835Fumarate reductase, flavoprotein subunit (frdA); Similar to GB:U14003 SP:P00363 GB:J01611 PID:145263 PID:536998 percent identity: 75.54; identified by sequence similarity; putative.
epmA protein networkhttps://string-db.org/network/71421.HI_0836lysyl-tRNA synthetase analog (genX); With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-depende [...]
cpxR protein networkhttps://string-db.org/network/71421.HI_0837Response regulator (cpxR); Member of a two-component regulatory system.
bamE protein networkhttps://string-db.org/network/71421.HI_0838Small protein A, putative; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
HI_0839 protein networkhttps://string-db.org/network/71421.HI_0839Conserved hypothetical protein; Similar to SP:P33920 PID:405914 GB:U00096 PID:1788513 percent identity: 52.38; identified by sequence similarity; putative.
HI_0840 protein networkhttps://string-db.org/network/71421.HI_0840Conserved hypothetical protein; Similar to SP:P33921 PID:405915 GB:U00096 PID:1788514 percent identity: 45.71; identified by sequence similarity; putative; Belongs to the UPF0352 family.
HI_0841 protein networkhttps://string-db.org/network/71421.HI_0841Conserved hypothetical protein; Similar to SP:P33922 PID:453987 GB:U00096 PID:1788515 percent identity: 41.57; identified by sequence similarity; putative; To E.coli YejM.
HI_0842 protein networkhttps://string-db.org/network/71421.HI_0842Predicted coding region HI0842; Hypothetical protein; identified by GeneMark; putative; Belongs to the metallo-dependent hydrolases superfamily.
HI_0843 protein networkhttps://string-db.org/network/71421.HI_0843Predicted coding region HI0843; Hypothetical protein; identified by GeneMark; putative.
mobA protein networkhttps://string-db.org/network/71421.HI_0844Molybdopterin-guanine dinucleotide biosynthesis protein (mob); Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine [...]
HI_0845 protein networkhttps://string-db.org/network/71421.HI_0845Conserved hypothetical protein; Similar to GB:L19201 SP:P32126 PID:304964 GB:U00096 PID:1790289 percent identity: 65.91; identified by sequence similarity; putative; To E.coli YihD.
dsbA protein networkhttps://string-db.org/network/71421.HI_0846Periplasmic oxidoreductase (por); Involved in disulfide-bond formation. Required for HI transformation. Acts by transferring its disulfide bond to other proteins; Belongs to the thioredoxin famil [...]
HI_0847 protein networkhttps://string-db.org/network/71421.HI_0847Conserved hypothetical protein; Not known, a mutation in ORF3 causes a slight decrease in transformation efficiency.
trmA protein networkhttps://string-db.org/network/71421.HI_0848tRNA (uracil-5-)-methyltransferase (trmA); Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341 [...]
rsmJ protein networkhttps://string-db.org/network/71421.HI_0849Conserved hypothetical protein; Specifically methylates the guanosine in position 1516 of 16S rRNA.
HI_0850 protein networkhttps://string-db.org/network/71421.HI_0850sigma-E factor regulatory protein, putative; Similar to SP:P46187 PID:987645 PID:1045631 PID:1050877 GB:U00096 percent identity: 35.66; identified by sequence similarity; putative.
mobB protein networkhttps://string-db.org/network/71421.HI_0851Molybdopterin-guanine dinucleotide biosynthesis protein B (mobB); GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor, and not [...]
hsrA protein networkhttps://string-db.org/network/71421.HI_0852Conserved hypothetical transmembrane protein; Similar to GB:L10328 SP:P31474 PID:290604 GB:U00096 PID:1790195 percent identity: 44.91; identified by sequence similarity; putative.
hbpA protein networkhttps://string-db.org/network/71421.HI_0853Heme-binding lipoprotein (dppA); Important role in heme acquisition or metabolism; Belongs to the bacterial solute-binding protein 5 family.
HI_0854 protein networkhttps://string-db.org/network/71421.HI_0854Conserved hypothetical protein; Involved in heme iron utilization. Catalyzes the degradation of heme to biliverdin, with the release of iron and carbon monoxide.
HI_0855 protein networkhttps://string-db.org/network/71421.HI_0855Conserved hypothetical protein; Similar to SP:P42627 PID:606050 GB:U00096 PID:1789496 percent identity: 65.43; identified by sequence similarity; putative; Belongs to the UPF0597 family.
polA protein networkhttps://string-db.org/network/71421.HI_0856DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
zapA protein networkhttps://string-db.org/network/71421.HI_0857Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the forma [...]
HI_0858 protein networkhttps://string-db.org/network/71421.HI_0858Conserved hypothetical protein; Involved in the removal of 5-formyltetrahydrofolate. In vitro, it is a potent inhibitor of various folate-dependent enzymes in the C1 metabolism network and in viv [...]
clpB protein networkhttps://string-db.org/network/71421.HI_0859ATP-dependent Clp protease, ATPase subunit (clpB); Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, [...]
rlmB protein networkhttps://string-db.org/network/71421.HI_0860Conserved hypothetical protein; Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
rnr protein networkhttps://string-db.org/network/71421.HI_0861Virulence-associated protein (vacB); 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
HI_0862 protein networkhttps://string-db.org/network/71421.HI_0862Conserved hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q pre [...]
pdxH protein networkhttps://string-db.org/network/71421.HI_0863Pyridoxamine phosphate oxidase (pdxH); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
bipA protein networkhttps://string-db.org/network/71421.HI_0864GTP-binding protein; A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analo [...]
glnA protein networkhttps://string-db.org/network/71421.HI_0865Glutamine synthetase (glnA); Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.
HI_0866 protein networkhttps://string-db.org/network/71421.HI_0866Predicted coding region HI0866; Hypothetical protein; identified by GeneMark; putative.
HI_0867 protein networkhttps://string-db.org/network/71421.HI_0867Lipopolysaccharide biosynthesis protein, putative; Similar to SP:P37781 PID:454902 percent identity: 23.26; identified by sequence similarity; putative.
HI_0868 protein networkhttps://string-db.org/network/71421.HI_0868Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 35.37; identified by sequence similarity; putative; Belongs to the glycosyltransferase 2 family.
HI_0869 protein networkhttps://string-db.org/network/71421.HI_0869Predicted coding region HI0869; Hypothetical protein; identified by GeneMark; putative.
HI_0870 protein networkhttps://string-db.org/network/71421.HI_0870Predicted coding region HI0870; Hypothetical protein; identified by GeneMark; putative.
HI_0870.1 protein networkhttps://string-db.org/network/71421.HI_0870.1Predicted coding region HI0870.1; Brute Force ORF; identified by GeneMark; putative.
HI_0871 protein networkhttps://string-db.org/network/71421.HI_0871Predicted coding region HI0871; Hypothetical protein; identified by GeneMark; putative.
HI_0872 protein networkhttps://string-db.org/network/71421.HI_0872Undecaprenyl-phosphate galactosephosphotransferase (rfbP); May function as a sugar transferase.
rffG protein networkhttps://string-db.org/network/71421.HI_0873DTDP-glucose 4,6-dehydratase (rffG); Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6- deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction; B [...]
HI_0874 protein networkhttps://string-db.org/network/71421.HI_0874Predicted coding region HI0874; Hypothetical protein; identified by GeneMark; putative.
ndk protein networkhttps://string-db.org/network/71421.HI_0876Nucleoside diphosphate kinase (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mecha [...]
obg protein networkhttps://string-db.org/network/71421.HI_0877GTP-binding protein (yhbZ); An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays [...]
HI_0878 protein networkhttps://string-db.org/network/71421.HI_0878Conserved hypothetical protein; Similar to SP:P28636 PID:216638 PID:606122 GB:U00096 PID:1789575 percent identity: 49.34; identified by sequence similarity; putative.
rpmA protein networkhttps://string-db.org/network/71421.HI_0879Ribosomal protein L27 (rpL27); Similar to GB:D13267 SP:P02427 PID:216637 PID:606123 GB:U00096 percent identity: 87.06; identified by sequence similarity; putative; Belongs to the bacterial riboso [...]
rplU protein networkhttps://string-db.org/network/71421.HI_0880Ribosomal protein L21 (rpL21); This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
ispB protein networkhttps://string-db.org/network/71421.HI_0881Octaprenyl-diphosphate synthase (ispB); Supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone and menaquinone.
queH protein networkhttps://string-db.org/network/71421.HI_0882Predicted coding region HI0882; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) an [...]
HI_0883 protein networkhttps://string-db.org/network/71421.HI_0883Amino acid carrier protein, putative; Similar to PID:757741 SP:Q45068 PID:1405464 GB:AL009126 percent identity: 39.09; identified by sequence similarity; putative.
arcA protein networkhttps://string-db.org/network/71421.HI_0884Aerobic respiration control protein ARCA (arcA); Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions (By similarity).
dsbD protein networkhttps://string-db.org/network/71421.HI_0885Thiol:disulfide interchange protein (dsbD); Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes [...]
HI_0886 protein networkhttps://string-db.org/network/71421.HI_0886Predicted coding region HI0886; Hypothetical protein; identified by GeneMark; putative.
purH protein networkhttps://string-db.org/network/71421.HI_0887Phosphoribosylaminoimidazolecarboxamide formyltransferase (purH); Similar to SP:P15639 GB:J05126 GB:X51950 PID:147420 PID:396345 percent identity: 77.19; identified by sequence similarity; putati [...]
purD protein networkhttps://string-db.org/network/71421.HI_0888Phosphoribosylamine--glycine ligase (purD); Similar to SP:P15640 GB:J05126 GB:X51950 PID:147421 PID:396344 percent identity: 75.18; identified by sequence similarity; putative.
glyA protein networkhttps://string-db.org/network/71421.HI_0889Serine hydroxymethyltransferase (serine methylase) (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This react [...]
coaE protein networkhttps://string-db.org/network/71421.HI_0890Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
yacG protein networkhttps://string-db.org/network/71421.HI_0891Conserved hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which proba [...]
rhlB protein networkhttps://string-db.org/network/71421.HI_0892ATP-dependent RNA helicase (rhlB); DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. [...]
HI_0893 protein networkhttps://string-db.org/network/71421.HI_0893Transcriptional repressor (Bm3R1); Similar to GB:S87512 SP:P43506 PID:623036 PID:247052 percent identity: 23.89; identified by sequence similarity; putative.
HI_0894 protein networkhttps://string-db.org/network/71421.HI_0894Lipoprotein, putative; Similar to GB:U14993 SP:P43505 PID:438192 PID:550460 percent identity: 30.92; identified by sequence similarity; putative.
HI_0895 protein networkhttps://string-db.org/network/71421.HI_0895Acriflavine resistance protein (acrB); Could be a drug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
HI_0896 protein networkhttps://string-db.org/network/71421.HI_0896Cell division protein (ftsN); Similar to GB:L19201 SP:P29131 GB:L14281 PID:290448 PID:305036 percent identity: 29.08; identified by sequence similarity; putative; To E.coli FtsN repeat regions.
emrB protein networkhttps://string-db.org/network/71421.HI_0897Multidrug resistance protein B (emrB); Confers resistance to antibiotics; Belongs to the major facilitator superfamily. EmrB family.
emrA protein networkhttps://string-db.org/network/71421.HI_0898Multidrug resistance protein A (emrA); Confers resistance to antibiotics; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
folA protein networkhttps://string-db.org/network/71421.HI_0899Dihydrofolate reductase (folA); Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity); Belongs [...]
proB protein networkhttps://string-db.org/network/71421.HI_0900Glutamate 5-kinase (gamma-glutamyl kinase) (proB); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
rppH protein networkhttps://string-db.org/network/71421.HI_0901Conserved hypothetical protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state th [...]
HI_0902 protein networkhttps://string-db.org/network/71421.HI_0902Conserved hypothetical protein; Similar to GB:L77117 SP:Q57883 PID:1591145 percent identity: 28.84; identified by sequence similarity; putative.
lgt protein networkhttps://string-db.org/network/71421.HI_0904Prolipoprotein diacylglyceryl transferase (lgt); Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotei [...]
thyA protein networkhttps://string-db.org/network/71421.HI_0905Thymidylate synthetase (thyA); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydr [...]
tadA protein networkhttps://string-db.org/network/71421.HI_0906Conserved hypothetical protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
HI_0907 protein networkhttps://string-db.org/network/71421.HI_0907Predicted coding region HI0907; Hypothetical protein; identified by GeneMark; putative.
HI_0908 protein networkhttps://string-db.org/network/71421.HI_0908Predicted coding region HI0908; Hypothetical protein; identified by GeneMark; putative.
secA protein networkhttps://string-db.org/network/71421.HI_0909Preprotein translocase SecA subunit (secA); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of [...]
mutT protein networkhttps://string-db.org/network/71421.HI_0910Mutator mutT protein (mutT); Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool. 8-oxo-dGTP is i [...]
kefBC protein networkhttps://string-db.org/network/71421.HI_0911Glutathione-regulated potassium efflux system protein (kefC); Transport system that facilitate potassium-efflux, possibly by potassium-proton antiport; Belongs to the monovalent cation:proton ant [...]
HI_0912 protein networkhttps://string-db.org/network/71421.HI_0912Predicted coding region HI0912; Hypothetical protein; identified by GeneMark; putative.
rpsB protein networkhttps://string-db.org/network/71421.HI_0913Ribosomal protein S2 (rpS2); Similar to GB:D26562 SP:P02351 GB:V00343 PID:42842 PID:473824 percent identity: 82.16; identified by sequence similarity; putative; Belongs to the universal ribosomal [...]
tsf protein networkhttps://string-db.org/network/71421.HI_0914Elongation factor Ts (tsf); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage [...]
lpxD protein networkhttps://string-db.org/network/71421.HI_0915UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase (lpxD); Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis [...]
omp26 protein networkhttps://string-db.org/network/71421.HI_0916Outer membrane protein, putative; Similar to PID:1935023 percent identity: 37.58; identified by sequence similarity; putative.
bamA protein networkhttps://string-db.org/network/71421.HI_0917Protective surface antigen D15; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
rsep protein networkhttps://string-db.org/network/71421.HI_0918Conserved hypothetical transmembrane protein; A site-2 regulated intramembrane protease (S2P) that cleaves a peptide bond in the transmembrane region of RseA. Part of a regulated intramembrane pr [...]
cdsA protein networkhttps://string-db.org/network/71421.HI_0919CDP-diglyceride synthetase (cdsA); Similar to GB:M11330 SP:P06466 PID:1208947 PID:145476 GB:U00096 percent identity: 48.39; identified by sequence similarity; putative.
uppS protein networkhttps://string-db.org/network/71421.HI_0920Conserved hypothetical protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E) [...]
leuS protein networkhttps://string-db.org/network/71421.HI_0921leucyl-tRNA synthetase (leuS); Similar to SP:P07813 GB:X06331 PID:41916 GB:U00096 PID:1651269 percent identity: 72.64; identified by sequence similarity; putative; Belongs to the class-I aminoacy [...]
lptE protein networkhttps://string-db.org/network/71421.HI_0922Rare lipoprotein B, putative; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS [...]
holA protein networkhttps://string-db.org/network/71421.HI_0923DNA polymerase III, delta subunit (holA); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to [...]
glyS protein networkhttps://string-db.org/network/71421.HI_0924glycyl-tRNA synthetase, beta chain (glyS); Similar to SP:P00961 GB:J01622 PID:146223 PID:466697 GB:U00096 percent identity: 69.67; identified by sequence similarity; putative.
HI_0925 protein networkhttps://string-db.org/network/71421.HI_0925Conserved hypothetical protein; Similar to SP:P45736 GB:U00096 PID:1279405 PID:1787546 percent identity: 41.75; identified by sequence similarity; putative; To E.coli YcjD and H.influenzae HI_116 [...]
HI_0926 protein networkhttps://string-db.org/network/71421.HI_0926Predicted coding region HI0926; Hypothetical protein; identified by GeneMark; putative.
glyQ protein networkhttps://string-db.org/network/71421.HI_0927glycyl-tRNA synthetase, alpha chain (glyQ); Similar to SP:P00960 GB:J01622 PID:146222 PID:146225 PID:466698 percent identity: 90.64; identified by sequence similarity; putative.
katA protein networkhttps://string-db.org/network/71421.HI_0928Catalase (hktE); Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; Belongs to the catalase family.
HI_0929 protein networkhttps://string-db.org/network/71421.HI_0929Conserved hypothetical protein; May be a ligase forming an amide bond. Shows ATPase activity (By similarity).
HI_0930 protein networkhttps://string-db.org/network/71421.HI_0930Predicted coding region HI0930; Hypothetical protein; identified by GeneMark; putative.
HI_0931 protein networkhttps://string-db.org/network/71421.HI_0931Predicted coding region HI0931; Hypothetical protein; identified by GeneMark; putative.
eno protein networkhttps://string-db.org/network/71421.HI_0932Enolase (eno); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
HI_0933 protein networkhttps://string-db.org/network/71421.HI_0933Conserved hypothetical transmembrane protein; Similar to SP:P37631 PID:912464 GB:U00096 PID:2367234 percent identity: 58.35; identified by sequence similarity; putative; To E.coli YhiN.
nrfF protein networkhttps://string-db.org/network/71421.HI_0934Cytochrome C-type biogenesis protein (nrfF); Possible subunit of a heme lyase; Belongs to the CcmH/CycL/Ccl2/NrfF family.
nrfX protein networkhttps://string-db.org/network/71421.HI_0935Thiol:disulfide interchange protein (dsbE); Could be involved in disulfide bond formation. Could catalyzes a late, reductive step in the assembly of periplasmic NrfA c- type cytochrome, probably [...]
nrfE protein networkhttps://string-db.org/network/71421.HI_0936Cytochrome C-type biogenesis; Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase (By similarity); Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
suhB protein networkhttps://string-db.org/network/71421.HI_0937Extragenic suppressor (suhB); Similar to GB:M34828 SP:P22783 PID:147899 GB:U00096 PID:1788882 percent identity: 65.12; identified by sequence similarity; putative; Belongs to the inositol monopho [...]
HI_0938 protein networkhttps://string-db.org/network/71421.HI_0938Predicted coding region HI0938; Hypothetical protein; identified by GeneMark; putative.
HI_0939 protein networkhttps://string-db.org/network/71421.HI_0939Predicted coding region HI0939; Hypothetical protein; identified by GeneMark; putative.
HI_0940 protein networkhttps://string-db.org/network/71421.HI_0940Predicted coding region HI0940; Hypothetical protein; identified by GeneMark; putative.
HI_0941 protein networkhttps://string-db.org/network/71421.HI_0941Predicted coding region HI0941; Hypothetical protein; identified by GeneMark; putative.
recC protein networkhttps://string-db.org/network/71421.HI_0942Exodeoxyribonuclease V, gamma chain (recC); A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive AT [...]
nrdR protein networkhttps://string-db.org/network/71421.HI_0943Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
ribD protein networkhttps://string-db.org/network/71421.HI_0944Riboflavin biosynthesis protein (ribD); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the N-ter [...]
degS protein networkhttps://string-db.org/network/71421.HI_0945Protease (degS); A site-1 protease (S1P) that cleaves the peptide bond between 'Val-148' and 'Ser-149' in RseA. Part of a regulated intramembrane proteolysis (RIP) cascade. When heat shock or oth [...]
mutM protein networkhttps://string-db.org/network/71421.HI_0946formamidopyrimidine-DNA glycosylase (fpg); Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. [...]
ddc protein networkhttps://string-db.org/network/71421.HI_0946.1L-2,4-diaminobutyrate decarboxylase; Similar to PID:893355 percent identity: 75.54; identified by sequence similarity; putative.
vapC2 protein networkhttps://string-db.org/network/71421.HI_0947Virulence associated protein C (vapC); Toxic component of a type II toxin-antitoxin (TA) system. An RNase. Its cognate antitoxin is VapB2 (By similarity). Belongs to the PINc/VapC protein family.
vapB2 protein networkhttps://string-db.org/network/71421.HI_0948Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of toxin VapC2 (By similarity).
dat protein networkhttps://string-db.org/network/71421.HI_0949Aminotransferase; Similar to PID:2340815 percent identity: 71.85; identified by sequence similarity; putative.
rpmG protein networkhttps://string-db.org/network/71421.HI_0950Ribosomal protein L33 (rpL33); Similar to GB:J01677 SP:P02436 PID:147709 PID:290486 GB:U00096 percent identity: 81.48; identified by sequence similarity; putative; Belongs to the bacterial riboso [...]
rpmB protein networkhttps://string-db.org/network/71421.HI_0951Ribosomal protein L28 (rpL28); Similar to GB:J01677 SP:P02428 PID:147708 PID:290487 GB:U00096 percent identity: 85.71; identified by sequence similarity; putative; Belongs to the bacterial riboso [...]
HI_0952 protein networkhttps://string-db.org/network/71421.HI_0952DNA repair protein (radC); Similar to GB:L10328 SP:P25531 GB:X63366 GB:X63367 PID:290488 percent identity: 49.77; identified by sequence similarity; putative; Belongs to the UPF0758 family.
coaBC protein networkhttps://string-db.org/network/71421.HI_0953DNA/pantothenate metabolism flavoprotein (dfp); Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'- phosphopantothenate to form 4-pho [...]
dut protein networkhttps://string-db.org/network/71421.HI_0954Deoxyuridinetriphosphatase (dut); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentra [...]
slmA protein networkhttps://string-db.org/network/71421.HI_0955Transcriptional regulator (ttk); Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhib [...]
HI_0956 protein networkhttps://string-db.org/network/71421.HI_0956Conserved hypothetical protein; Similar to SP:P45536 PID:606288 GB:U00096 PID:1789753 percent identity: 50.70; identified by sequence similarity; putative; Belongs to the UPF0270 family.
crp protein networkhttps://string-db.org/network/71421.HI_0957Catabolite gene activator (crp); A global transcription regulator required for bacterial competence. Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding (to consensus sequ [...]
rlmC protein networkhttps://string-db.org/network/71421.HI_0958RNA methyltransferase, putative; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U m [...]
nagZ protein networkhttps://string-db.org/network/71421.HI_0959Beta-hexosaminidase (exoII); Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving ris [...]
HI_0960 protein networkhttps://string-db.org/network/71421.HI_0960Predicted coding region HI0960; Hypothetical protein; identified by GeneMark; putative.
HI_0961 protein networkhttps://string-db.org/network/71421.HI_0961Hit-related protein; Hydrolyzes purine nucleotide phosphoramidates, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monophosphomorpholidate (AMP-morpholidate), guanosine 5'monoph [...]
ribF protein networkhttps://string-db.org/network/71421.HI_0963Riboflavin kinase / FMN adenylyltransferase (ribF); Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.
murJ protein networkhttps://string-db.org/network/71421.HI_0964Virulence factor (mviN); Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
rpsT protein networkhttps://string-db.org/network/71421.HI_0965Ribosomal protein S20 (rpS20); Binds directly to 16S ribosomal RNA.
HI_0966 protein networkhttps://string-db.org/network/71421.HI_0966Predicted coding region HI0966; Hypothetical protein; identified by GeneMark; putative.
menB protein networkhttps://string-db.org/network/71421.HI_0968Naphthoate synthase (menB); Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
menC protein networkhttps://string-db.org/network/71421.HI_0969O-succinylbenzoate-CoA synthase (menC); Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
aroQ protein networkhttps://string-db.org/network/71421.HI_09703-dehydroquinase (aroQ); Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
accB protein networkhttps://string-db.org/network/71421.HI_0971acetyl-CoA carboxylase, biotin carboxyl carrier protein (accB); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of [...]
accC protein networkhttps://string-db.org/network/71421.HI_0972acetyl-CoA carboxylase, biotin carboxylase (accC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier p [...]
HI_0973 protein networkhttps://string-db.org/network/71421.HI_0973Predicted coding region HI0973; Hypothetical protein; identified by GeneMark; putative.
HI_0974 protein networkhttps://string-db.org/network/71421.HI_0974Predicted coding region HI0974; Hypothetical protein; identified by GeneMark; putative.
HI_0974.1 protein networkhttps://string-db.org/network/71421.HI_0974.1Conserved hypothetical protein; Similar to SP:P45566 PID:606197 GB:U00096 PID:1789655 percent identity: 46.15; identified by sequence similarity; putative.
panF protein networkhttps://string-db.org/network/71421.HI_0975Sodium/pantothenate symporter (panF); Catalyzes the sodium-dependent uptake of extracellular pantothenate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
HI_0976 protein networkhttps://string-db.org/network/71421.HI_0976Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 25.21; identified by sequence similarity; putative.
HI_0976.1 protein networkhttps://string-db.org/network/71421.HI_0976.1Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 24.90; identified by sequence similarity; putative.
HI_0977 protein networkhttps://string-db.org/network/71421.HI_0977Cell filamentation protein (fic); Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
prmA protein networkhttps://string-db.org/network/71421.HI_0978Ribosomal protein L11 methyltransferase (prmA); Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
dusB protein networkhttps://string-db.org/network/71421.HI_0979Nitrogen fixation protein (nifR3); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridi [...]
fis protein networkhttps://string-db.org/network/71421.HI_0980Hin recombinational enhancer binding protein (fis); Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory [...]
smpB protein networkhttps://string-db.org/network/71421.HI_0981Small protein B (smpB); Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. [...]
pfkA protein networkhttps://string-db.org/network/71421.HI_09826-phosphofructokinase (pfkA); Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
HI_0983 protein networkhttps://string-db.org/network/71421.HI_0983Predicted coding region HI0983; Hypothetical protein; identified by GeneMark; putative.
HI_0984 protein networkhttps://string-db.org/network/71421.HI_0984Conserved hypothetical protein; Similar to GB:D10483 SP:P11288 PID:216438 PID:537248 PID:1128976 percent identity: 62.20; identified by sequence similarity; putative; Belongs to the UPF0246 famil [...]
dprA protein networkhttps://string-db.org/network/71421.HI_0985DNA processing chain A (dprA); Essential for efficient chromosomal DNA transformation but not required for plasmid transformation. Its disruption can be partially complemented by the smf gene of [...]
leuA protein networkhttps://string-db.org/network/71421.HI_09862-isopropylmalate synthase (leuA); Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2- [...]
leuB protein networkhttps://string-db.org/network/71421.HI_09873-isopropylmalate dehydrogenase (beta-IPM dehydrogenase) (leuB); Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The [...]
leuC protein networkhttps://string-db.org/network/71421.HI_09883-isopropylmalate dehydratase, alpha subunit (leuC); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
leuD protein networkhttps://string-db.org/network/71421.HI_09893-isopropylmalate dehydratase small subunit (leuD); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD fami [...]
iga protein networkhttps://string-db.org/network/71421.HI_0990Immunoglobin A1 protease (iga1); Virulence factor; cleaves host immunoglobulin A producing intact Fc and Fab fragments.
recF protein networkhttps://string-db.org/network/71421.HI_0991DNA/ATP binding protein (recF); The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linea [...]
dnaN protein networkhttps://string-db.org/network/71421.HI_0992DNA polymerase III, beta subunit (dnaN); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clam [...]
dnaA protein networkhttps://string-db.org/network/71421.HI_0993Chromosomal replication initiator protein (dnaA); Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically do [...]
tbpA protein networkhttps://string-db.org/network/71421.HI_0994Transferrin-binding protein 1 precursor (tbp1); Acts as a transferrin receptor and is required for transferrin utilization; Belongs to the TonB-dependent receptor family.
tbpB protein networkhttps://string-db.org/network/71421.HI_0995Transferrin-binding protein 2 precursor (tbp2); Acts as a transferrin receptor and is required for transferrin utilization.
HI_0996 protein networkhttps://string-db.org/network/71421.HI_0996Predicted coding region HI0996; Hypothetical protein; identified by GeneMark; putative.
HI_0997 protein networkhttps://string-db.org/network/71421.HI_0997Predicted coding region HI0997; Hypothetical protein; identified by GeneMark; putative.
rpmH protein networkhttps://string-db.org/network/71421.HI_0998Ribosomal protein L34 (rpL34); Similar to GB:L10328 SP:P02437 GB:J01602 GB:M11056 PID:145759 percent identity: 86.36; identified by sequence similarity; putative; Belongs to the bacterial ribosom [...]
rnpA protein networkhttps://string-db.org/network/71421.HI_0999Ribonuclease P (rnpA); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protei [...]
HI_1000 protein networkhttps://string-db.org/network/71421.HI_1000Hemolysin, putative; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
yidC protein networkhttps://string-db.org/network/71421.HI_1001Inner membrane protein, 60 kDa (yidC); Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membra [...]
mnmE protein networkhttps://string-db.org/network/71421.HI_1002Thiophene and furan oxidation protein (thdF); Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U3 [...]
ppiD protein networkhttps://string-db.org/network/71421.HI_1004Peptidyl-prolyl cis-trans isomerse, putative; PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins (By similarity).
HI_1005 protein networkhttps://string-db.org/network/71421.HI_1005Conserved hypothetical protein; Similar to GB:U00096 SP:P75785 PID:1787035 percent identity: 33.76; identified by sequence similarity; putative.
lspA protein networkhttps://string-db.org/network/71421.HI_1006Lipoprotein signal peptidase (lspA); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
ispH protein networkhttps://string-db.org/network/71421.HI_1007Penicillin tolerance protein (lytB); Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphospha [...]
HI_1008 protein networkhttps://string-db.org/network/71421.HI_1008Conserved hypothetical protein; Similar to GB:U00096 SP:P77415 PID:1580713 PID:1773126 PID:1786646 percent identity: 37.04; identified by sequence similarity; putative.
HI_1009 protein networkhttps://string-db.org/network/71421.HI_1009Glycerol-3-phosphate regulon repressor (glpR); Similar to SP:P09392 GB:M96795 PID:146186 PID:606358 GB:U00096 percent identity: 29.37; identified by sequence similarity; putative.
ltnD protein networkhttps://string-db.org/network/71421.HI_10103-hydroxyisobutyrate dehydrogenase, putative; Catalyzes oxidation of L-threonate to 2-oxo-tetronate. Can use either NAD(+) or NADP(+) as cosubstrate, with a preference for NAD(+).
otnK protein networkhttps://string-db.org/network/71421.HI_1011Conserved hypothetical protein; Catalyzes the ATP-dependent phosphorylation of 3-oxo- tetronate to 3-oxo-tetronate 4-phosphate.
otnC protein networkhttps://string-db.org/network/71421.HI_1012Sugar isomerase, putative; Catalyzes the decarboxylation of 3-oxo-tetronate 4-phosphate to dihydroxyacetone phosphate (DHAP) and CO(2). Belongs to the aldolase class II family. AraD/FucA subfamil [...]
otnI protein networkhttps://string-db.org/network/71421.HI_1013Conserved hypothetical protein; Catalyzes the isomerization of 2-oxo-tetronate to 3-oxo- tetronate.
denD protein networkhttps://string-db.org/network/71421.HI_1014Conserved hypothetical protein; Catalyzes oxidation of D-erythronate to 2-oxo-tetronate. Can use either NAD(+) or NADP(+) as cosubstrate, with a preference for NAD(+).
HI_1015 protein networkhttps://string-db.org/network/71421.HI_1015Gluconate permease (gntP); Similar to SP:P39835 PID:606350 GB:U00096 PID:1789820 percent identity: 32.35; identified by sequence similarity; putative.
HI_1016 protein networkhttps://string-db.org/network/71421.HI_1016Predicted coding region HI1016; Hypothetical protein; identified by GeneMark; putative.
HI_1017 protein networkhttps://string-db.org/network/71421.HI_1017Glycerol uptake facilitator protein (glpF); Similar to GB:M99611 SP:P18156 PID:142991 PID:142997 PID:2226136 percent identity: 41.28; identified by sequence similarity; putative; Belongs to the M [...]
thiB protein networkhttps://string-db.org/network/71421.HI_1019Thiamin ABC transporter, periplasmic-binding protein (tbpA); Part of the ABC transporter complex ThiBPQ involved in thiamine import.
thiP protein networkhttps://string-db.org/network/71421.HI_1020Thiamin ABC transporter, permease protein, putative; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Probably responsible for the translocation of the substrate across the [...]
thiQ protein networkhttps://string-db.org/network/71421.HI_1021Thiamin ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to [...]
bioB protein networkhttps://string-db.org/network/71421.HI_1022Biotin synthetase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM su [...]
tktA protein networkhttps://string-db.org/network/71421.HI_1023Transketolase 1 (tktA); Catalyzes the reversible transfer of a two-carbon ketol group from sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate, producing xylulose-5-phosphate and ribose-5-pho [...]
sgbH protein networkhttps://string-db.org/network/71421.HI_1024Hexulose-6-phosphate synthase, putative; Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P; Belongs to the HPS/KGPDC family. KGPDC subfamily.
sgbE protein networkhttps://string-db.org/network/71421.HI_1025L-ribulose-5-phosphate 4-epimerase (araD); Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond [...]
sgbU protein networkhttps://string-db.org/network/71421.HI_1026Hexulose-6-phosphate isomerase, putative; Catalyzes the isomerization of L-xylulose-5-phosphate to L- ribulose-5-phosphate.
lyx protein networkhttps://string-db.org/network/71421.HI_1027L-xylulose kinase (lyx); Similar to SP:P37677 PID:466718 GB:U00096 PID:1790005 percent identity: 53.93; identified by sequence similarity; putative; Belongs to the FGGY kinase family.
HI_1028 protein networkhttps://string-db.org/network/71421.HI_1028Conserved hypothetical protein; Similar to SP:P37676 PID:466717 GB:U00096 PID:1790004 percent identity: 55.80; identified by sequence similarity; putative.
HI_1029 protein networkhttps://string-db.org/network/71421.HI_1029Conserved hypothetical transmembrane protein; Similar to SP:P37675 PID:466716 GB:U00096 PID:1790003 percent identity: 65.88; identified by sequence similarity; putative.
HI_1030 protein networkhttps://string-db.org/network/71421.HI_1030Conserved hypothetical transmembrane protein; Similar to SP:P37674 PID:466715 GB:U00096 PID:1790002 percent identity: 37.50; identified by sequence similarity; putative.
dlgD protein networkhttps://string-db.org/network/71421.HI_1031Conserved hypothetical protein; Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
HI_1032 protein networkhttps://string-db.org/network/71421.HI_1032Transcriptional regulator, putative; Similar to SP:P37671 PID:466712 GB:U00096 PID:1789999 percent identity: 63.74; identified by sequence similarity; putative.
serB protein networkhttps://string-db.org/network/71421.HI_1033Phosphoserine phosphatase (serB); Catalyzes the dephosphorylation of phosphoserine (P-Ser).
HI_1034 protein networkhttps://string-db.org/network/71421.HI_1034Conserved hypothetical protein; Similar to GB:U00096 SP:P77482 PID:1773110 PID:1786629 percent identity: 60.95; identified by sequence similarity; putative; Belongs to the UPF0234 family.
corA protein networkhttps://string-db.org/network/71421.HI_1035Magnesium and cobalt transport protein (corA); Mediates influx of magnesium ions. Can also mediate cobalt and manganese uptake (By similarity). Alternates between open and closed states. Activate [...]
HI_1036 protein networkhttps://string-db.org/network/71421.HI_1036Conserved hypothetical protein; Similar to PID:801880 SP:P52059 PID:801882 percent identity: 41.24; identified by sequence similarity; putative.
HI_1037 protein networkhttps://string-db.org/network/71421.HI_1037Conserved hypothetical protein; Similar to PID:984579 GB:U00096 SP:Q47147 PID:1552793 PID:1786417 percent identity: 47.45; identified by sequence similarity; putative.
HI_1037.1 protein networkhttps://string-db.org/network/71421.HI_1037.1Predicted coding region HI1037.1; Brute Force ORF; identified by GeneMark; putative.
HI_1038 protein networkhttps://string-db.org/network/71421.HI_1038Conserved hypothetical protein; Similar to GB:L77117 PID:1592175 percent identity: 32.34; identified by sequence similarity; putative; To M.jannaschii MJ1544 and MJ1637.
hindVRP protein networkhttps://string-db.org/network/71421.HI_1040Type II restriction enzyme, putative; Similar to SP:P25261 SP:P24599 PID:43474 percent identity: 43.56; identified by sequence similarity; putative.
hindVM protein networkhttps://string-db.org/network/71421.HI_1041Modification methylase; This methylase recognizes the double-stranded sequence GRCGYC, causes specific methylation on C-? on both strands, and protects the DNA from cleavage by the HindV endonucl [...]
HI_1043 protein networkhttps://string-db.org/network/71421.HI_1043Ferredoxin-type protein (napF); Similar to SP:P33939 PID:453990 GB:U00096 PID:1736849 PID:1788536 percent identity: 33.08; identified by sequence similarity; putative.
dmsD protein networkhttps://string-db.org/network/71421.HI_1044Conserved hypothetical protein; Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade [...]
dmsC protein networkhttps://string-db.org/network/71421.HI_1045Anaerobic dimethyl sulfoxide reductase, chain C (dmsC); Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. DmsC anchors the DmsAB dimer to the membrane and sta [...]
dmsB protein networkhttps://string-db.org/network/71421.HI_1046Anaerobic dimethyl sulfoxide reductase, chain B (dmsB); Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.
dmsA protein networkhttps://string-db.org/network/71421.HI_1047Anaerobic dimethyl sulfoxide reductase, chain A (dmsA); Catalyzes the reduction of dimethyl sulfoxide (DMSO) to dimethyl sulfide (DMS). The terminal DMSO reductase can also use various sulfoxides [...]
HI_1048 protein networkhttps://string-db.org/network/71421.HI_1048Predicted coding region HI1048; Hypothetical protein; identified by GeneMark; putative.
HI_1049 protein networkhttps://string-db.org/network/71421.HI_1049Mercuric ion transport protein (merT); Similar to SP:P04140 GB:Z00027 PID:154899 PID:43716 percent identity: 25.00; identified by sequence similarity; putative.
HI_1050 protein networkhttps://string-db.org/network/71421.HI_1050Mercuric ion scavenger protein (merP); Similar to PID:1143574 SP:Q54463 percent identity: 29.89; identified by sequence similarity; putative.
HI_1051 protein networkhttps://string-db.org/network/71421.HI_1051ABC transporter, ATP-binding protein; Similar to GB:AL009126 percent identity: 33.76; identified by sequence similarity; putative.
HI_1052 protein networkhttps://string-db.org/network/71421.HI_1052Transcriptional regulator, araC family, putative; Similar to SP:P35319 PID:581707 percent identity: 25.67; identified by sequence similarity; putative.
HI_1053 protein networkhttps://string-db.org/network/71421.HI_1053Conserved hypothetical protein; Similar to GB:M66060 SP:P27749 PID:141897 percent identity: 31.86; identified by sequence similarity; putative.
HI_1054 protein networkhttps://string-db.org/network/71421.HI_1054Conserved hypothetical protein; Similar to PID:1381738 percent identity: 92.49; identified by sequence similarity; putative.
HI_1055 protein networkhttps://string-db.org/network/71421.HI_1055Predicted coding region HI1055; Hypothetical protein; identified by GeneMark; putative.
HI_1056 protein networkhttps://string-db.org/network/71421.HI_1056Predicted coding region HI1056; Hypothetical protein; identified by GeneMark; putative; Belongs to the N(4)/N(6)-methyltransferase family.
HI_1058 protein networkhttps://string-db.org/network/71421.HI_1058Predicted coding region HI1058; Hypothetical protein; identified by GeneMark; putative.
rnhB protein networkhttps://string-db.org/network/71421.HI_1059Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
lpxB protein networkhttps://string-db.org/network/71421.HI_1060lipid-A-disaccharide synthetase (lpxB); Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated gly [...]
lpxA protein networkhttps://string-db.org/network/71421.HI_1061UDP-N-acetylglucosamine acetyltransferase (lpxA); Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
fabZ protein networkhttps://string-db.org/network/71421.HI_1062(3R)-hydroxymyristol (acyl carrier protein) dehydrase (fabZ); Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain satur [...]
HI_1063 protein networkhttps://string-db.org/network/71421.HI_1063Predicted coding region HI1063; Hypothetical protein; identified by GeneMark; putative.
HI_1064 protein networkhttps://string-db.org/network/71421.HI_1064Conserved hypothetical protein; Similar to GB:U00096 SP:P75785 PID:1787035 percent identity: 30.70; identified by sequence similarity; putative.
pyrH protein networkhttps://string-db.org/network/71421.HI_1065Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.
nrfD protein networkhttps://string-db.org/network/71421.HI_1066Nitrite reductase, transmembrane protein (nrfD); Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes; Belongs to the NrfD family.
nrfC protein networkhttps://string-db.org/network/71421.HI_1067Nitrite reductase, Fe-S protein (nrfC); Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes.
nrfB protein networkhttps://string-db.org/network/71421.HI_1068Nitrite reductase, cytochrome C-type protein (nrfB); Plays a role in nitrite reduction.
nrfA protein networkhttps://string-db.org/network/71421.HI_1069Nitrite reductase, cytochrome C552 (nrfA); Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family.
hrpA protein networkhttps://string-db.org/network/71421.HI_1070ATP-dependent helicase (hrpa); Similar to SP:P43329 PID:806328 GB:U00096 PID:1742299 PID:1742304 percent identity: 70.29; identified by sequence similarity; putative.
HI_1073 protein networkhttps://string-db.org/network/71421.HI_1073Conserved hypothetical protein; Similar to SP:P32065 GB:U01030 GB:X73413 PID:312767 PID:523332 percent identity: 43.55; identified by sequence similarity; putative.
HI_1074 protein networkhttps://string-db.org/network/71421.HI_1074Conserved hypothetical protein; Similar to GB:U00096 PID:1788090 percent identity: 51.37; identified by sequence similarity; putative.
HI_1075 protein networkhttps://string-db.org/network/71421.HI_1075Cytochrome D ubiquinol oxidase, subunit II (cydB); Probable cytochrome oxidase subunit; Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
HI_1076 protein networkhttps://string-db.org/network/71421.HI_1076Cytochrome D ubiquinol oxidase, subunit I (cydA); Probable cytochrome oxidase subunit.
pyrG protein networkhttps://string-db.org/network/71421.HI_1077CTP synthetase (pyrG); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions wi [...]
pnuC protein networkhttps://string-db.org/network/71421.HI_1077.1Predicted coding region HI1077.1; Required for nicotinamide riboside transport across the inner membrane.
HI_1078 protein networkhttps://string-db.org/network/71421.HI_1078Amino acid ABC transporter, ATP-binding protein; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for energy coupling to the transport system; [...]
HI_1079 protein networkhttps://string-db.org/network/71421.HI_1079Amino acid ABC transporter, permease protein; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for the translocation of the substrate across t [...]
HI_1080 protein networkhttps://string-db.org/network/71421.HI_1080Amino acid ABC transporter, periplasmic-binding protein; Probably part of a binding-protein-dependent transport system for an amino acid; Belongs to the bacterial solute-binding protein 3 family.
murA protein networkhttps://string-db.org/network/71421.HI_1081UDP-N-acetylglucosamine 1-carboxyvinyltransferase (murZ); Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
HI_1082 protein networkhttps://string-db.org/network/71421.HI_1082Conserved hypothetical protein; Similar to SP:P43781 PID:606128 GB:U00096 PID:1789581 percent identity: 46.51; identified by sequence similarity; putative; Belongs to the BolA/IbaG family.
mlaB protein networkhttps://string-db.org/network/71421.HI_1083Anti-sigma factor B antagonist, putative; Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane b [...]
mlaC protein networkhttps://string-db.org/network/71421.HI_1084Conserved hypothetical protein; Involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membran [...]
mlaD protein networkhttps://string-db.org/network/71421.HI_1085Conserved hypothetical protein; Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrogra [...]
mlaE protein networkhttps://string-db.org/network/71421.HI_1086Conserved hypothetical protein; Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrogra [...]
mlaF protein networkhttps://string-db.org/network/71421.HI_1087ABC transporter, ATP-binding protein; Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by re [...]
sodA protein networkhttps://string-db.org/network/71421.HI_1088Superoxide dismutase (sodA); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide di [...]
ccmA protein networkhttps://string-db.org/network/71421.HI_1089Heme exporter ATP-binding protein A (ccmA); Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, [...]
ccmB protein networkhttps://string-db.org/network/71421.HI_1090Heme exporter protein B (ccmB); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
ccmC protein networkhttps://string-db.org/network/71421.HI_1091Heme exporter protein C (ccmC); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
ccmD protein networkhttps://string-db.org/network/71421.HI_1092Heme exporter protein D (ccmD); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
ccmE protein networkhttps://string-db.org/network/71421.HI_1093Cytochrome C-type biogenesis protein (ccmE); Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes i [...]
ccmF protein networkhttps://string-db.org/network/71421.HI_1094Cytochrome C-type biogenesis protein (ccmF); Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase; Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
dsbE protein networkhttps://string-db.org/network/71421.HI_1095Thiol:disulfide interchange protein (dsbE); Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of dis [...]
HI_1098 protein networkhttps://string-db.org/network/71421.HI_1098Predicted coding region HI1098; Hypothetical protein; identified by GeneMark; putative.
HI_1099 protein networkhttps://string-db.org/network/71421.HI_1099Predicted coding region HI1099; Hypothetical protein; identified by GeneMark; putative.
ligA protein networkhttps://string-db.org/network/71421.HI_1100DNA ligase (lig); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy [...]
zipA protein networkhttps://string-db.org/network/71421.HI_1101Cell division protein ZipA, putative; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring [...]
cysZ protein networkhttps://string-db.org/network/71421.HI_1102Cysteine synthetase, putative (cysZ); High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pa [...]
cysK protein networkhttps://string-db.org/network/71421.HI_1103Cysteine synthetase (cysK); Similar to GB:M21451 SP:P11096 GB:X12615 PID:145686 PID:41201 percent identity: 70.65; identified by sequence similarity; putative; Belongs to the cysteine synthase/cy [...]
HI_1104 protein networkhttps://string-db.org/network/71421.HI_1104Transporter protein; Similar to PID:1842056 percent identity: 29.56; identified by sequence similarity; putative.
rfaF protein networkhttps://string-db.org/network/71421.HI_1105ADP-heptose--LPS heptosyltransferase II (rfaF); Similar to SP:P37692 PID:466758 GB:U00096 PID:1790050 percent identity: 63.58; identified by sequence similarity; putative.
xylR protein networkhttps://string-db.org/network/71421.HI_1106Xylose operon regluatory protein (xylR); Regulatory protein for the xylBAFGHR operon.
HI_1107 protein networkhttps://string-db.org/network/71421.HI_1107Na+/H+ antiporter (nhaC); Similar to GB:M73530 SP:P27611 PID:143245 PID:2209268 percent identity: 37.50; identified by sequence similarity; putative.
xylH protein networkhttps://string-db.org/network/71421.HI_1109D-xylose ABC transporter, permease protein (xylH); Part of the binding-protein-dependent transport system for D- xylose. Probably responsible for the translocation of the substrate across the mem [...]
xylG protein networkhttps://string-db.org/network/71421.HI_1110D-xylose ABC transporter, ATP-binding protein (xylG); Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the [...]
xylF protein networkhttps://string-db.org/network/71421.HI_1111D-xylose ABC transporter, periplasmic-binding protein (xylF); Involved in the high-affinity D-xylose membrane transport system. Binds with high affinity to xylose (By similarity). Belongs to the [...]
xylA protein networkhttps://string-db.org/network/71421.HI_1112Xylose isomerase (xylA); Similar to GB:X04691 SP:P00944 GB:K01996 GB:S68257 PID:148279 percent identity: 71.30; identified by sequence similarity; putative; Belongs to the xylose isomerase family [...]
xylB protein networkhttps://string-db.org/network/71421.HI_1113Xylulose kinase; Catalyzes the phosphorylation of D-xylulose to D-xylulose 5- phosphate; Belongs to the FGGY kinase family.
hldD protein networkhttps://string-db.org/network/71421.HI_1114ADP-L-glycero-D-mannoheptose-6-epimerase (rfaD); Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 [...]
HI_1115 protein networkhttps://string-db.org/network/71421.HI_1115Thioredoxin, putative; Similar to PID:1213065 SP:P52229 percent identity: 36.36; identified by sequence similarity; putative.
deoC protein networkhttps://string-db.org/network/71421.HI_1116Deoxyribose-phosphate aldolase (deoC); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/F [...]
comM protein networkhttps://string-db.org/network/71421.HI_1117Competence protein (comM); Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step.
engB protein networkhttps://string-db.org/network/71421.HI_1118Conserved hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase super [...]
HI_1119 protein networkhttps://string-db.org/network/71421.HI_1119Membrane protein (lapB); Similar to SP:P32181 GB:M59210 PID:387858 percent identity: 63.13; identified by sequence similarity; putative.
oppF protein networkhttps://string-db.org/network/71421.HI_1120Oligopeptide ABC transporter, ATP-binding protein (oppF); Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport syste [...]
oppD protein networkhttps://string-db.org/network/71421.HI_1121Oligopeptide ABC transporter, ATP-binding protein (oppD); Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport syste [...]
oppC protein networkhttps://string-db.org/network/71421.HI_1122Oligopeptide ABC transporter, permease protein (oppC); Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across [...]
oppB protein networkhttps://string-db.org/network/71421.HI_1123Oligopeptide ABC transporter, permease protein (oppB); Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across [...]
oppA protein networkhttps://string-db.org/network/71421.HI_1124Oligopeptide ABC transporter, periplasmic-binding protein (oppA); This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to f [...]
tal protein networkhttps://string-db.org/network/71421.HI_1125Transaldolase B (talB); Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
HI_1126 protein networkhttps://string-db.org/network/71421.HI_1126Predicted coding region HI1126; Hypothetical protein; identified by GeneMark; putative.
HI_1126.1 protein networkhttps://string-db.org/network/71421.HI_1126.1Predicted coding region HI1126.1; Hypothetical protein; identified by GeneMark; putative.
HI_1127 protein networkhttps://string-db.org/network/71421.HI_1127Predicted coding region HI1127; Hypothetical protein; identified by GeneMark; putative.
HI_1128 protein networkhttps://string-db.org/network/71421.HI_1128Predicted coding region HI1128; Hypothetical protein; identified by GeneMark; putative.
mraZ protein networkhttps://string-db.org/network/71421.HI_1129Conserved hypothetical protein; Similar to SP:P22186 GB:X52063 PID:40849 PID:42319 GB:U00096 percent identity: 59.21; identified by sequence similarity; putative; Belongs to the MraZ family.
rsmH protein networkhttps://string-db.org/network/71421.HI_1130Conserved hypothetical protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
ftsL protein networkhttps://string-db.org/network/71421.HI_1131Cell division protein (ftsL); Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division protei [...]
ftsI protein networkhttps://string-db.org/network/71421.HI_1132Penicillin-binding protein 3 (ftsI); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
murE protein networkhttps://string-db.org/network/71421.HI_1133UDP-N-acetylmuramyl-tripeptide synthetase (murE); Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthes [...]
murF protein networkhttps://string-db.org/network/71421.HI_1134UDP-MurNAc-pentapeptide synthetase (murF); Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the [...]
mraY protein networkhttps://string-db.org/network/71421.HI_1135phospho-N-acetylmuramoyl-pentapeptide- transferase E (mraY); First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 famil [...]
murD protein networkhttps://string-db.org/network/71421.HI_1136UDP-N-acetylmuramoylalanine--D-glutamate ligase (murD); Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the M [...]
ftsW protein networkhttps://string-db.org/network/71421.HI_1137Cell division protein (ftsW); Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
murG protein networkhttps://string-db.org/network/71421.HI_1138Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
murC protein networkhttps://string-db.org/network/71421.HI_1139UDP-N-acetylmuramate--alanine ligase (murC); Cell wall formation; Belongs to the MurCDEF family.
ddl protein networkhttps://string-db.org/network/71421.HI_1140D-alanine--D-alanine ligase (ddlB); Cell wall formation.
ftsQ protein networkhttps://string-db.org/network/71421.HI_1141Cell division protein (ftsQ); Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division protei [...]
ftsA protein networkhttps://string-db.org/network/71421.HI_1142Cell division protein (ftsA); Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
ftsZ protein networkhttps://string-db.org/network/71421.HI_1143Cell division protein (ftsZ); Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the t [...]
lpxC protein networkhttps://string-db.org/network/71421.HI_1144UDP-3-0-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase (lpxC); Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the commi [...]
pheA protein networkhttps://string-db.org/network/71421.HI_1145Chorismate mutase / prephenate dehydratase (pheA); Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
HI_1146 protein networkhttps://string-db.org/network/71421.HI_1146Conserved hypothetical protein; Displays ATPase and GTPase activities.
ptsN protein networkhttps://string-db.org/network/71421.HI_1147Nitrogen regulatory IIA protein (ptsN); Not known; lacks the phosphorylation site found in other PtsN proteins.
lptB protein networkhttps://string-db.org/network/71421.HI_1148ABC transporter, ATP-binding protein; Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably [...]
lptA protein networkhttps://string-db.org/network/71421.HI_1149Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge betwee [...]
lptC protein networkhttps://string-db.org/network/71421.HI_1150Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer [...]
HI_1151 protein networkhttps://string-db.org/network/71421.HI_1151Conserved hypothetical protein; Similar to SP:P26650 GB:M95096 PID:148266 PID:537076 GB:U00096 percent identity: 62.20; identified by sequence similarity; putative; Belongs to the UPF0307 family.
pmbA protein networkhttps://string-db.org/network/71421.HI_1152pmbA protein (pmbA); Probable metalloprotease; Belongs to the peptidase U62 family.
hpt protein networkhttps://string-db.org/network/71421.HI_1153Hypoxanthine phosphoribosyltransferase (hpt); Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine (By similarity). Belongs to the purine/pyrimidi [...]
HI_1154 protein networkhttps://string-db.org/network/71421.HI_1154Proton glutamate symport protein, putative; Similar to GB:U00096 PID:1742823 PID:1742828 PID:1788024 percent identity: 55.98; identified by sequence similarity; putative.
nrdG protein networkhttps://string-db.org/network/71421.HI_1155Anaerobic ribonucleoside-triphosphate reductase activating protein (nrdG); Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic fre [...]
cydC protein networkhttps://string-db.org/network/71421.HI_1156Transport ATP-binding protein (cydC); Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity); Belongs to the ABC transpo [...]
cydD protein networkhttps://string-db.org/network/71421.HI_1157ATP-binding protein protein (cydD); Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity); Belongs to the ABC transport [...]
trxB protein networkhttps://string-db.org/network/71421.HI_1158Thioredoxin reductase (trxB); Similar to GB:J03762 SP:P09625 PID:148073 PID:347239 GB:U00096 percent identity: 75.95; identified by sequence similarity; putative.
HI_1159 protein networkhttps://string-db.org/network/71421.HI_1159Conserved hypothetical protein; Similar to GB:U00096 SP:P77395 PID:1773174 PID:1786700 percent identity: 50.89; identified by sequence similarity; putative.
hemH protein networkhttps://string-db.org/network/71421.HI_1160Ferrochelatase (hemH); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
HI_1161 protein networkhttps://string-db.org/network/71421.HI_1161Conserved hypothetical protein; Similar to GB:M24143 SP:P15050 PID:450383 PID:522184 GB:U00096 percent identity: 49.26; identified by sequence similarity; putative; Belongs to the thioesterase Pa [...]
HI_1162 protein networkhttps://string-db.org/network/71421.HI_1162Conserved hypothetical protein; Similar to SP:P45736 GB:U00096 PID:1279405 PID:1787546 percent identity: 42.86; identified by sequence similarity; putative; To E.coli YcjD and H.influenzae HI_092 [...]
HI_1163 protein networkhttps://string-db.org/network/71421.HI_1163Conserved hypothetical protein; Similar to GB:U00096 SP:P77748 PID:1742760 PID:1787977 percent identity: 60.82; identified by sequence similarity; putative.
ompA protein networkhttps://string-db.org/network/71421.HI_1164Outer membrane protein P5 (ompA); With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows sl [...]
grxD protein networkhttps://string-db.org/network/71421.HI_1165Conserved hypothetical protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters.
hisC2 protein networkhttps://string-db.org/network/71421.HI_1166Histidinol-phosphate aminotransferase (hisH); Similar to SP:P17731 PID:143814 GB:AL009126 percent identity: 38.70; identified by sequence similarity; putative; Belongs to the class-II pyridoxal-p [...]
serC protein networkhttps://string-db.org/network/71421.HI_1167Phosphoserine aminotransferase (serC); Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [...]
HI_1168 protein networkhttps://string-db.org/network/71421.HI_1168Conserved hypothetical protein; Similar to GB:U00096 PID:1788317 percent identity: 56.14; identified by sequence similarity; putative; Belongs to the UPF0265 family.
HI_1169 protein networkhttps://string-db.org/network/71421.HI_1169Predicted coding region HI1169; Hypothetical protein; identified by GeneMark; putative.
HI_1170 protein networkhttps://string-db.org/network/71421.HI_1170Predicted coding region HI1170; Hypothetical protein; identified by GeneMark; putative; To the C-terminal of para-aminobenzoate synthase component I.
HI_1171 protein networkhttps://string-db.org/network/71421.HI_1171Anthranilate synthase component II (trpG); Similar to GB:M36636 SP:P00902 PID:141800 percent identity: 34.04; identified by sequence similarity; putative.
metK protein networkhttps://string-db.org/network/71421.HI_1172S-adenosylmethionine synthetase (metX); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMe [...]
sprT protein networkhttps://string-db.org/network/71421.HI_1173Sprt protein (sprT); Similar to SP:P39902 PID:1208420 PID:882473 GB:U00096 PID:1789313 percent identity: 46.00; identified by sequence similarity; putative; Belongs to the SprT family.
opa protein networkhttps://string-db.org/network/71421.HI_1174Opacity protein, putative; Similar to GB:X15780 PID:1333789 percent identity: 38.76; identified by sequence similarity; putative; Belongs to the opacity porin family.
HI_1176 protein networkhttps://string-db.org/network/71421.HI_1176Predicted coding region HI1176; Hypothetical protein; identified by GeneMark; putative.
artM protein networkhttps://string-db.org/network/71421.HI_1177Arginine ABC transporter, permease protein (artM); Part of the ABC transporter complex ArtPIQM involved in arginine transport. Probably responsible for the translocation of the substrate across t [...]
artQ protein networkhttps://string-db.org/network/71421.HI_1178Arginine ABC transporter, permease protein (artQ); Part of the ABC transporter complex ArtPIQM involved in arginine transport. Probably responsible for the translocation of the substrate across t [...]
artI protein networkhttps://string-db.org/network/71421.HI_1179Arginine ABC transporter, periplasmic-binding protein (artI); Part of the ABC transporter complex ArtPIQM involved in arginine transport.
artP protein networkhttps://string-db.org/network/71421.HI_1180Arginine ABC transporter, ATP-binding protein (artP); Part of the ABC transporter complex ArtPIQM involved in arginine transport. Probably responsible for energy coupling to the transport system [...]
gmhA protein networkhttps://string-db.org/network/71421.HI_1181Phosphoheptose isomerase (gmhA); Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.
ligA-2 protein networkhttps://string-db.org/network/71421.HI_1182Predicted coding region HI1182; Catalyzes efficient strand joining on a single nicked DNA.
HI_1183 protein networkhttps://string-db.org/network/71421.HI_1183Predicted coding region HI1183; Hypothetical protein; identified by GeneMark; putative.
dppF protein networkhttps://string-db.org/network/71421.HI_1184Dipeptide ABC transporter, ATP-binding protein (dppF); Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system (By [...]
dppD protein networkhttps://string-db.org/network/71421.HI_1185Dipeptide ABC transporter, ATP-binding protein (dppD); Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system (By [...]
dppC protein networkhttps://string-db.org/network/71421.HI_1186Dipeptide ABC transporter, permease protein (dppC); Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the m [...]
dppB protein networkhttps://string-db.org/network/71421.HI_1187Dipeptide ABC transporter, permease protein (dppB); Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the m [...]
uvrD protein networkhttps://string-db.org/network/71421.HI_1188DNA helicase II (uvrD); May process damage occurring in non-replicating regions of DNA to produce recombinational intermediates for sister strand recombinational exchange.
queE protein networkhttps://string-db.org/network/71421.HI_1189Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to th [...]
queD protein networkhttps://string-db.org/network/71421.HI_11906-pyruvoyl tetrahydrobiopterin synthase, putative; Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.
queC protein networkhttps://string-db.org/network/71421.HI_1191Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
HI_1192 protein networkhttps://string-db.org/network/71421.HI_1192Predicted coding region HI1192; Hypothetical protein; identified by GeneMark; putative.
ilvE protein networkhttps://string-db.org/network/71421.HI_1193Branched-chain-amino-acid transaminase (ilvE); Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
gcvA protein networkhttps://string-db.org/network/71421.HI_1194Glycine cleavage system transcriptional activator (gcvA); Not known, the gcv operon regulated by the E.coli homolog does not exist in H.influenzae, so it probably acts as a transcriptional regula [...]
rlmM protein networkhttps://string-db.org/network/71421.HI_1195Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE f [...]
sucC protein networkhttps://string-db.org/network/71421.HI_1196succinyl-CoA synthetase, beta subunit (sucC); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and t [...]
sucD protein networkhttps://string-db.org/network/71421.HI_1197succinyl-CoA synthetase, alpha subunit (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and [...]
HI_1198 protein networkhttps://string-db.org/network/71421.HI_1198Conserved hypothetical protein; Similar to SP:P45847 PID:602960 GB:U00096 PID:1787521 percent identity: 71.30; identified by sequence similarity; putative; Belongs to the SUA5 family.
rluB protein networkhttps://string-db.org/network/71421.HI_1199Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family.
cysB protein networkhttps://string-db.org/network/71421.HI_1200Cys regulon transcriptional activator (cysB); This protein is a positive regulator of gene expression for the cysteine regulon. The inducer for CysB is N-acetylserine (By similarity).
prmB protein networkhttps://string-db.org/network/71421.HI_1201Adenine specific methylase, putative; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subf [...]
HI_1202 protein networkhttps://string-db.org/network/71421.HI_1202Conserved hypothetical protein; Similar to GB:U00096 PID:1788671 percent identity: 53.09; identified by sequence similarity; putative; Belongs to the UPF0115 family.
pta protein networkhttps://string-db.org/network/71421.HI_1203Phosphate acetyltransferase (pta); Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family.
ackA protein networkhttps://string-db.org/network/71421.HI_1204Acetate kinase (ackA); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
HI_1205 protein networkhttps://string-db.org/network/71421.HI_1205Conserved hypothetical protein; Similar to GB:U00096 PID:1788632 GB:U00096 PID:1788632 percent identity: 45.45; identified by sequence similarity; putative.
cvpA protein networkhttps://string-db.org/network/71421.HI_1206Colicin V production protein (cvpA); Similar to GB:J01666 SP:P08550 PID:146367 PID:147415 GB:U00096 percent identity: 64.74; identified by sequence similarity; putative.
purF protein networkhttps://string-db.org/network/71421.HI_1207Amidophosphoribosyltransferase (purF); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrim [...]
HI_1208 protein networkhttps://string-db.org/network/71421.HI_1208Conserved hypothetical protein; Similar to GB:L42023 PID:1007092 PID:1221333 PID:1205451 PID:1574138 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the NAD(P)-d [...]
argR protein networkhttps://string-db.org/network/71421.HI_1209Arginine repressor (argR); Regulates arginine biosynthesis genes; Belongs to the ArgR family.
mdh protein networkhttps://string-db.org/network/71421.HI_1210Malate dehydrogenase (mdh); Catalyzes the reversible oxidation of malate to oxaloacetate.
lysS protein networkhttps://string-db.org/network/71421.HI_1211lysyl-tRNA synthetase (lysU); Similar to GB:U14003 GB:J03795 SP:P13030 SP:P14825 GB:M30630 percent identity: 70.38; identified by sequence similarity; putative; Belongs to the class-II aminoacyl- [...]
dsbC protein networkhttps://string-db.org/network/71421.HI_1213Thiol:disulfide interchange protein (dsbC); Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the pro [...]
recJ protein networkhttps://string-db.org/network/71421.HI_1214single-stranded-DNA-specific exonuclease (recJ); Single-stranded-DNA-specific exonuclease. Required for many types of recombinational events, although the stringency of the requirement for RecJ a [...]
HI_1215 protein networkhttps://string-db.org/network/71421.HI_1215Thiol:disulfide interchange protein (dsbA); Similar to PID:840949 SP:P50024 percent identity: 22.28; identified by sequence similarity; putative.
mtnN protein networkhttps://string-db.org/network/71421.HI_1216Pfs protein (pfs); Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thiorib [...]
HI_1217 protein networkhttps://string-db.org/network/71421.HI_1217Transferrin-binding protein, putative; Probable receptor, TonB-dependent.
HI_1218 protein networkhttps://string-db.org/network/71421.HI_1218L-lactate permease (lctP); May play a role in L-lactate transport; Belongs to the lactate permease family.
cmk1 protein networkhttps://string-db.org/network/71421.HI_1219Cytidylate kinase 1 (cmkA); Similar to SP:P23863 PID:42839 GB:U00096 PID:1651431 PID:1651438 percent identity: 64.52; identified by sequence similarity; putative.
rpsA protein networkhttps://string-db.org/network/71421.HI_1220Ribosomal protein S1 (rpS1); Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity [...]
ihfB protein networkhttps://string-db.org/network/71421.HI_1221Integration host factor, beta-subunit (himD); This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as [...]
lapA protein networkhttps://string-db.org/network/71421.HI_1222Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
lapB protein networkhttps://string-db.org/network/71421.HI_1223Conserved hypothetical protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of [...]
pyrF protein networkhttps://string-db.org/network/71421.HI_1224Orotidine 5'-phosphate decarboxylase (pyrF); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 s [...]
HI_1225 protein networkhttps://string-db.org/network/71421.HI_1225Conserved hypothetical protein; Similar to GB:J02768 SP:P08245 PID:147476 GB:U00096 PID:1787538 percent identity: 77.14; identified by sequence similarity; putative; Belongs to the SUI1 family.
HI_1225.1 protein networkhttps://string-db.org/network/71421.HI_1225.1Conserved hypothetical protein; Similar to GB:U00096 PID:1788842 PID:1805556 percent identity: 48.03; identified by sequence similarity; putative; Belongs to the DnaA family. HdA subfamily.
uraA protein networkhttps://string-db.org/network/71421.HI_1227Uracil permease (uraA); Transport of uracil in the cell; Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily.
upp protein networkhttps://string-db.org/network/71421.HI_1228Uracil phosphoribosyltransferase (upp); Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
dnaX protein networkhttps://string-db.org/network/71421.HI_1229DNA polymerase III, subunits gamma and tau (dnaX); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhib [...]
apt protein networkhttps://string-db.org/network/71421.HI_1230Adenine phosphoribosyltransferase (apt); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
lpdA protein networkhttps://string-db.org/network/71421.HI_1231Dihydrolipoamide dehydrogenase (lpdA); Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase fa [...]
aceF protein networkhttps://string-db.org/network/71421.HI_1232Dihydrolipoamide acetyltransferase (aceF); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic [...]
aceE protein networkhttps://string-db.org/network/71421.HI_1233Pyruvate dehydrogenase, E1 component (aceE); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
mgsA protein networkhttps://string-db.org/network/71421.HI_1234Methylglyoxal synthase (mgsA); Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
HI_1235 protein networkhttps://string-db.org/network/71421.HI_1235Predicted coding region HI1235; Hypothetical protein; identified by GeneMark; putative.
HI_1236 protein networkhttps://string-db.org/network/71421.HI_1236Conserved hypothetical protein; Similar to PID:868023 GB:U00096 PID:1787900 percent identity: 26.52; identified by sequence similarity; putative.
dnaK protein networkhttps://string-db.org/network/71421.HI_1237Heat shock protein 70 (dnaK); Acts as a chaperone; Belongs to the heat shock protein 70 family.
dnaJ protein networkhttps://string-db.org/network/71421.HI_1238Heat shock protein (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in [...]
proA protein networkhttps://string-db.org/network/71421.HI_1239Gamma-glutamyl phosphate reductase (proA); Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes c [...]
HI_1240 protein networkhttps://string-db.org/network/71421.HI_1240Conserved hypothetical transmembrane protein; Similar to GB:L10328 SP:P31432 PID:290496 GB:U00096 PID:1790078 percent identity: 63.55; identified by sequence similarity; putative.
HI_1241 protein networkhttps://string-db.org/network/71421.HI_1241Predicted coding region HI1241; Hypothetical protein; identified by GeneMark; putative.
bcr protein networkhttps://string-db.org/network/71421.HI_1242Bicyclomycin resistance protein (bcr); Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance. Probable membrane translocase (By similarity). Belongs to the major facilitator superfa [...]
rsuA protein networkhttps://string-db.org/network/71421.HI_124316s pseudouridylate 516 synthase (rsuA); Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family.
HI_1244 protein networkhttps://string-db.org/network/71421.HI_1244Predicted coding region HI1244; Hypothetical protein; identified by GeneMark; putative.
maeB protein networkhttps://string-db.org/network/71421.HI_1245Malate oxidoreductase, putative; Similar to GB:U00096 PID:1788806 PID:1799885 PID:1799887 percent identity: 68.69; identified by sequence similarity; putative; In the C-terminal section; belongs [...]
HI_1246 protein networkhttps://string-db.org/network/71421.HI_1246Predicted coding region HI1246; Hypothetical protein; identified by GeneMark; putative.
uvrB protein networkhttps://string-db.org/network/71421.HI_1247Excinuclease ABC, subunit B (uvrB); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA [...]
HI_1248 protein networkhttps://string-db.org/network/71421.HI_1248Predicted coding region HI1248; Efflux system for nickel and cobalt; Belongs to the NiCoT transporter (TC 2.A.52) family.
HI_1249 protein networkhttps://string-db.org/network/71421.HI_1249Predicted coding region HI1249; Hypothetical protein; identified by GeneMark; putative.
HI_1250 protein networkhttps://string-db.org/network/71421.HI_1250Predicted coding region HI1250; Hypothetical protein; identified by GeneMark; putative.
HI_1251 protein networkhttps://string-db.org/network/71421.HI_1251Virulence associated protein A (vapA); Similar to PID:1002991 PID:563265 SP:Q46560 percent identity: 38.10; identified by sequence similarity; putative; Belongs to the VapA/VapI family.
ettA protein networkhttps://string-db.org/network/71421.HI_1252ABC transporter, ATP-binding protein; A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elonga [...]
HI_1253 protein networkhttps://string-db.org/network/71421.HI_1253Conserved hypothetical protein; Similar to PID:968932 GB:U00096 PID:1787464 percent identity: 31.73; identified by sequence similarity; putative.
tmcA protein networkhttps://string-db.org/network/71421.HI_1254Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
HI_1255 protein networkhttps://string-db.org/network/71421.HI_1255Predicted coding region HI1255; Hypothetical protein; identified by GeneMark; putative.
HI_1256 protein networkhttps://string-db.org/network/71421.HI_1256Predicted coding region HI1256; Hypothetical protein; identified by GeneMark; putative.
HI_1257 protein networkhttps://string-db.org/network/71421.HI_1257Predicted coding region HI1257; Hypothetical protein; identified by GeneMark; putative.
mfd protein networkhttps://string-db.org/network/71421.HI_1258Transcription-repair coupling factor (mfd); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its trunca [...]
HI_1259 protein networkhttps://string-db.org/network/71421.HI_1259Periplasmic serine protease; Similar to SP:P39099 PID:558912 PID:606173 PID:984379 GB:U00096 percent identity: 59.30; identified by sequence similarity; putative.
accD protein networkhttps://string-db.org/network/71421.HI_1260acetyl-CoA carboxylase carboxyl transferase subunit beta (accD); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its [...]
folC protein networkhttps://string-db.org/network/71421.HI_1261Folylpolyglutamate synthase/dihydrofolate synthase (folC); Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydro [...]
sanA protein networkhttps://string-db.org/network/71421.HI_1262sanA protein (sanA); Participates in the barrier function of the cell envelope.
metXA protein networkhttps://string-db.org/network/71421.HI_1263Homoserine acetyltransferase (met2); Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. Utilizes a ping-pong kinetic mechanism in which the acetyl group of ac [...]
gyrA protein networkhttps://string-db.org/network/71421.HI_1264DNA gyrase, subunit A (gyrA); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromoso [...]
HI_1265 protein networkhttps://string-db.org/network/71421.HI_1265Conserved hypothetical protein; Similar to GB:U00096 SP:P75838 PID:1787133 percent identity: 66.90; identified by sequence similarity; putative.
HI_1266 protein networkhttps://string-db.org/network/71421.HI_1266Predicted coding region HI1266; Hypothetical protein; identified by GeneMark; putative.
HI_1268 protein networkhttps://string-db.org/network/71421.HI_1268Predicted coding region HI1268; Hypothetical protein; identified by GeneMark; putative.
HI_1269 protein networkhttps://string-db.org/network/71421.HI_1269Predicted coding region HI1269; Hypothetical protein; identified by GeneMark; putative.
HI_1272 protein networkhttps://string-db.org/network/71421.HI_1272ABC transporter, ATP-binding protein; Similar to GB:AE000511 SP:O05732 PID:2072456 PID:2314024 percent identity: 34.43; identified by sequence similarity; putative; Belongs to the ABC transporter [...]
HI_1273 protein networkhttps://string-db.org/network/71421.HI_1273Conserved hypothetical protein; Similar to PID:1816658 percent identity: 37.25; identified by sequence similarity; putative.
gloB protein networkhttps://string-db.org/network/71421.HI_1274Hydroxyacylglutathione hydrolase, putative; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
tehB protein networkhttps://string-db.org/network/71421.HI_1275Tellurite resistance protein (tehB); Probable S-adenosyl-L-methionine-dependent methyltransferase. Plays a role in both resistance to oxidative damage and heme uptake/utilization. Also protects H [...]
metG protein networkhttps://string-db.org/network/71421.HI_1276methionyl-tRNA synthetase (metG); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
mrp protein networkhttps://string-db.org/network/71421.HI_1277ATP-binding protein (mrp); Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
HI_1278 protein networkhttps://string-db.org/network/71421.HI_1278NAD(P)H-flavin oxidoreductase; Similar to GB:D17743 SP:P46072 PID:517169 percent identity: 33.33; identified by sequence similarity; putative.
neuA protein networkhttps://string-db.org/network/71421.HI_1279Acylneuraminate cytidylyltransferase (neuA); Similar to GB:M95053 GB:X78068 GB:U04328 PID:460146 PID:520734 percent identity: 47.06; identified by sequence similarity; putative; Belongs to the CM [...]
HI_1280 protein networkhttps://string-db.org/network/71421.HI_1280Conserved hypothetical protein; Similar to GB:M29945 PID:1197032 percent identity: 50.43; identified by sequence similarity; putative.
rimP protein networkhttps://string-db.org/network/71421.HI_1282Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
nusA protein networkhttps://string-db.org/network/71421.HI_1283N utilization substance protein A (nusA); Participates in both transcription termination and antitermination.
infB protein networkhttps://string-db.org/network/71421.HI_1284Translation initiation factor 2 (infB); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding [...]
HI_1285 protein networkhttps://string-db.org/network/71421.HI_1285Type I restriction enzyme (hsdR); Subunit R is required for both nuclease and ATPase activities, but not for modification.
HI_1286 protein networkhttps://string-db.org/network/71421.HI_1286Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipar [...]
HI_1287 protein networkhttps://string-db.org/network/71421.HI_1287Type I modification enzyme (hsdM); Methylation of specific adenine residues; required for both restriction and modification activities.
rbfA protein networkhttps://string-db.org/network/71421.HI_1288Ribosome binding factor A (rbfA); One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits [...]
truB protein networkhttps://string-db.org/network/71421.HI_1289tRNA pseudouridine 55 synthase (truB); Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 sub [...]
tyrA protein networkhttps://string-db.org/network/71421.HI_1290Chorismate mutase / prephenate dehydrogenase (tyrA); Similar to SP:Q02287 GB:M74135 GB:X60420 PID:415010 PID:43345 percent identity: 58.86; identified by sequence similarity; putative.
queF protein networkhttps://string-db.org/network/71421.HI_1291Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
HI_1292 protein networkhttps://string-db.org/network/71421.HI_1292Predicted coding region HI1292; Hypothetical protein; identified by GeneMark; putative.
HI_1293 protein networkhttps://string-db.org/network/71421.HI_1293Conserved hypothetical protein; Similar to PID:882706 GB:U00096 SP:Q46926 PID:1789176 percent identity: 36.89; identified by sequence similarity; putative; Belongs to the SufE family.
csd protein networkhttps://string-db.org/network/71421.HI_1295nifS protein, putative; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
HI_1296 protein networkhttps://string-db.org/network/71421.HI_1296Nuclease, putative; Similar to SP:P29769 percent identity: 46.62; identified by sequence similarity; putative; Belongs to the thermonuclease family.
HI_1297 protein networkhttps://string-db.org/network/71421.HI_1297Conserved hypothetical protein; Similar to SP:P33372 PID:405872 GB:U00096 PID:1788463 percent identity: 41.18; identified by sequence similarity; putative.
HI_1298 protein networkhttps://string-db.org/network/71421.HI_1298Conserved hypothetical transmembrane protein; Similar to SP:P33373 PID:405873 GB:U00096 PID:1788464 percent identity: 43.52; identified by sequence similarity; putative.
uup protein networkhttps://string-db.org/network/71421.HI_1300ABC transporter, ATP-binding protein; Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in po [...]
can protein networkhttps://string-db.org/network/71421.HI_1301Carbonic anhydrase, putative; Similar to PID:1513236 percent identity: 57.55; identified by sequence similarity; putative; Belongs to the beta-class carbonic anhydrase family.
asnS protein networkhttps://string-db.org/network/71421.HI_1302asparaginyl-tRNA synthetase (asnS); Similar to GB:M33145 SP:P17242 GB:X68192 PID:147935 PID:41000 percent identity: 80.65; identified by sequence similarity; putative.
ribH protein networkhttps://string-db.org/network/71421.HI_1303Riboflavin synthase, beta chain (ribH); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. T [...]
nusB protein networkhttps://string-db.org/network/71421.HI_1304N utilization substance protein B (nusB); Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequen [...]
thiL protein networkhttps://string-db.org/network/71421.HI_1305Thiamin-monophosphate kinase (thiL); Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to t [...]
pgpA protein networkhttps://string-db.org/network/71421.HI_1306Phosphatidylglycerophosphatase A (pgpA); Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
HI_1307 protein networkhttps://string-db.org/network/71421.HI_1307Conserved hypothetical protein; Similar to GB:U00096 SP:P75693 PID:1657525 PID:1786522 percent identity: 26.87; identified by sequence similarity; putative.
dapB protein networkhttps://string-db.org/network/71421.HI_1308Dihydrodipicolinate reductase (dapB); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
HI_1309 protein networkhttps://string-db.org/network/71421.HI_1309Conserved hypothetical protein; Similar to SP:P37910 GB:U00096 PID:1788568 percent identity: 54.41; identified by sequence similarity; putative.
HI_1310 protein networkhttps://string-db.org/network/71421.HI_1310Predicted coding region HI1310; Hypothetical protein; identified by GeneMark; putative.
pheS protein networkhttps://string-db.org/network/71421.HI_1311phenylalanyl-tRNA synthetase, alpha subunit (pheS); Similar to GB:V00291 SP:P08312 PID:146345 PID:43070 GB:U00096 percent identity: 75.00; identified by sequence similarity; putative; Belongs to [...]
pheT protein networkhttps://string-db.org/network/71421.HI_1312phenylalanyl-tRNA synthetase, beta subunit (pheT); Similar to GB:K02844 SP:P07395 PID:146346 PID:43071 GB:U00096 percent identity: 65.28; identified by sequence similarity; putative; Belongs to t [...]
ihfA protein networkhttps://string-db.org/network/71421.HI_1313Integration host factor, alpha-subunit (himA); This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well a [...]
HI_1314 protein networkhttps://string-db.org/network/71421.HI_1314Lipoprotein (nlpC); Similar to GB:M14031 SP:P23898 PID:145446 GB:U00096 PID:1742788 percent identity: 53.85; identified by sequence similarity; putative.
HI_1315 protein networkhttps://string-db.org/network/71421.HI_1315Predicted coding region HI1315; Hypothetical protein; identified by GeneMark; putative.
HI_1316 protein networkhttps://string-db.org/network/71421.HI_1316Predicted coding region HI1316; Hypothetical protein; identified by GeneMark; putative.
HI_1317 protein networkhttps://string-db.org/network/71421.HI_1317Conserved hypothetical protein; Similar to GB:U00096 SP:P39173 PID:1736408 PID:1742898 PID:1788080 percent identity: 39.01; identified by sequence similarity; putative.
infC protein networkhttps://string-db.org/network/71421.HI_1318Translation initiation factor 3 (infC); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus [...]
rpmI protein networkhttps://string-db.org/network/71421.HI_1319Ribosomal protein L35 (rpL35); Similar to SP:P07085 GB:U00096 PID:1742796 PID:1742809 PID:1788010 percent identity: 78.46; identified by sequence similarity; putative; Belongs to the bacterial ri [...]
rplT protein networkhttps://string-db.org/network/71421.HI_1320Ribosomal protein L20 (rpL20); Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing [...]
recB protein networkhttps://string-db.org/network/71421.HI_1321Exodeoxyribonuclease V, beta chain (recB); A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP [...]
recD protein networkhttps://string-db.org/network/71421.HI_1322Exodeoxyribonuclease V, alpha chain (recD); A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive AT [...]
matP protein networkhttps://string-db.org/network/71421.HI_1323Conserved hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter ma [...]
HI_1324 protein networkhttps://string-db.org/network/71421.HI_1324Lon protease, putative; Similar to GB:D00863 SP:P36772 PID:402504 percent identity: 24.16; identified by sequence similarity; putative.
fabA protein networkhttps://string-db.org/network/71421.HI_13253-hydroxydecanoyl-(acyl carrier-protein) dehydratase (fabA); Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2) [...]
HI_1326 protein networkhttps://string-db.org/network/71421.HI_1326Predicted coding region HI1326; Hypothetical protein; identified by GeneMark; putative.
HI_1327 protein networkhttps://string-db.org/network/71421.HI_1327Predicted coding region HI1327; Hypothetical protein; identified by GeneMark; putative.
rpsO1 protein networkhttps://string-db.org/network/71421.HI_1328Ribosomal protein S15 (rpS15); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging [...]
HI_1328.1 protein networkhttps://string-db.org/network/71421.HI_1328.1Predicted coding region HI1328.1; Brute Force ORF; identified by GeneMark; putative; To insertion element IS1016 transposase.
HI_1329 protein networkhttps://string-db.org/network/71421.HI_1329IS1016-V6 protein (IS1016-V6); Similar to GB:X59756 percent identity: 54.71; identified by sequence similarity; putative.
dacB protein networkhttps://string-db.org/network/71421.HI_1330D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase (dacB); Not involved in transpeptidation but exclusively catalyzes a DD-carboxypeptidase and DD-endopeptidase reaction; Belong [...]
greA protein networkhttps://string-db.org/network/71421.HI_1331Transcription elongation factor (greA); Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trap [...]
HI_1333 protein networkhttps://string-db.org/network/71421.HI_1333Conserved hypothetical protein; Similar to SP:P42550 PID:606118 GB:U00096 PID:1789570 percent identity: 75.00; identified by sequence similarity; putative.
rlmE protein networkhttps://string-db.org/network/71421.HI_1334Cell division protein (ftsJ); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
ftsH protein networkhttps://string-db.org/network/71421.HI_1335Cell division protein (ftsH); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane protei [...]
folP-A protein networkhttps://string-db.org/network/71421.HI_1336Dihydropteroate synthase (folP-1); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the i [...]
glmM1 protein networkhttps://string-db.org/network/71421.HI_1337mrsA protein (mrsA); Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
sixA-A protein networkhttps://string-db.org/network/71421.HI_1338Conserved hypothetical protein; Similar to GB:U00096 PID:1788681 percent identity: 40.26; identified by sequence similarity; putative; Belongs to the SixA phosphatase family.
HI_1339 protein networkhttps://string-db.org/network/71421.HI_1339Predicted coding region HI1339; Hypothetical protein; identified by GeneMark; putative; Belongs to the LEA type 1 family.
HI_1340 protein networkhttps://string-db.org/network/71421.HI_1340Conserved hypothetical protein; Similar to PID:882689 GB:U00096 SP:Q46920 PID:1789158 percent identity: 58.08; identified by sequence similarity; putative; Belongs to the outer membrane factor (O [...]
HI_1341 protein networkhttps://string-db.org/network/71421.HI_1341Predicted coding region HI1341; Hypothetical protein; identified by GeneMark; putative.
uup-B protein networkhttps://string-db.org/network/71421.HI_1342ABC transporter, ATP-binding protein; Might play a role in ribosome assembly or function; this is missing the first ABC transporter domain compared to paralogs.
HI_1343 protein networkhttps://string-db.org/network/71421.HI_1343Predicted coding region HI1343; Hypothetical protein; identified by GeneMark; putative; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
potD-B protein networkhttps://string-db.org/network/71421.HI_1344Spermidine/putrescine ABC transporter, periplasmic-binding protein (potD); Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine. Polyamine binding [...]
potC protein networkhttps://string-db.org/network/71421.HI_1345Spermidine/putrescine ABC transporter, permease protein (potC); Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine; Belongs to the binding-protei [...]
potB protein networkhttps://string-db.org/network/71421.HI_1346Spermidine/putrescine ABC transporter, permease protein (potB); Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine; Belongs to the binding-protei [...]
potA protein networkhttps://string-db.org/network/71421.HI_1347Spermidine/putrescine ABC transporter, ATP-binding protein (potA); Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the tra [...]
pepT protein networkhttps://string-db.org/network/71421.HI_1348Peptidase T (pepT); Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
HI_1349 protein networkhttps://string-db.org/network/71421.HI_1349Conserved hypothetical protein; Similar to PID:1652428 percent identity: 31.37; identified by sequence similarity; putative; Belongs to the Dps family.
cdd protein networkhttps://string-db.org/network/71421.HI_1350Cytidine deaminase (cdd); This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
cmoB protein networkhttps://string-db.org/network/71421.HI_1351Conserved hypothetical protein; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 [...]
putP protein networkhttps://string-db.org/network/71421.HI_1352Sodium/proline symporter (proline permease) (putP); Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
rng protein networkhttps://string-db.org/network/71421.HI_1353Cytoplasmic axial filament protein (cafA); Involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of [...]
glnS protein networkhttps://string-db.org/network/71421.HI_1354glutaminyl-tRNA synthetase (glnS); Similar to GB:V01575 SP:P00962 GB:J01617 GB:M10187 PID:146168 percent identity: 76.28; identified by sequence similarity; putative.
HI_1355 protein networkhttps://string-db.org/network/71421.HI_1355Conserved hypothetical protein; Similar to GB:U00096 PID:1787429 percent identity: 45.70; identified by sequence similarity; putative; Belongs to the UPF0260 family.
malQ protein networkhttps://string-db.org/network/71421.HI_13564-alpha-glucanotransferase (malQ); Similar to GB:M32793 SP:P15977 PID:146715 PID:606351 GB:U00096 percent identity: 41.59; identified by sequence similarity; putative; Belongs to the disproportio [...]
glgB protein networkhttps://string-db.org/network/71421.HI_13571,4-alpha-glucan branching enzyme (glgB); Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan [...]
glgX protein networkhttps://string-db.org/network/71421.HI_1358Glycogen operon protein (glgX); Similar to GB:J01616 SP:P15067 PID:146135 PID:606366 GB:U00096 percent identity: 52.77; identified by sequence similarity; putative; Belongs to the glycosyl hydrol [...]
glgC protein networkhttps://string-db.org/network/71421.HI_1359Glucose-1-phosphate adenylyltransferase (glgC); Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction bet [...]
glgA protein networkhttps://string-db.org/network/71421.HI_1360Glycogen synthase (glgA); Synthesizes alpha-1,4-glucan chains using ADP-glucose.
glgP protein networkhttps://string-db.org/network/71421.HI_1361Glycogen phosphorylase (glgP); Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natura [...]
pntA protein networkhttps://string-db.org/network/71421.HI_1362NAD(P) transhydrogenase, subunit alpha (pntA); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belong [...]
pntB protein networkhttps://string-db.org/network/71421.HI_1363NAD(P) transhydrogenase, subunit beta (pntB); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs [...]
HI_1364 protein networkhttps://string-db.org/network/71421.HI_1364Transcriptional regulator, putative; Similar to SP:P37641 PID:466658 GB:U00096 PID:1789938 percent identity: 36.04; identified by sequence similarity; putative; Belongs to the LysR transcriptiona [...]
topA protein networkhttps://string-db.org/network/71421.HI_1365DNA topoisomerase I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one str [...]
azoR protein networkhttps://string-db.org/network/71421.HI_1366Acyl carrier protein phosphodiesterase (acpD); Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron don [...]
thrS protein networkhttps://string-db.org/network/71421.HI_1367threonyl-tRNA synthetase (thrS); Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acce [...]
pqqL protein networkhttps://string-db.org/network/71421.HI_1368Zinc protease, putative; Similar to SP:P31828 GB:X71917 PID:535004 GB:U00096 PID:1742451 percent identity: 28.76; identified by sequence similarity; putative.
HI_1369 protein networkhttps://string-db.org/network/71421.HI_1369Conserved hypothetical protein; Similar to SP:P31827 GB:X71917 PID:311346 GB:U00096 PID:1787771 percent identity: 25.46; identified by sequence similarity; putative; To E.coli YddB.
HI_1370 protein networkhttps://string-db.org/network/71421.HI_1370Molybdenum-pterin binding protein (mopI); Binds one mole of molybdenum per mole of protein and contains a pterin.
tusE protein networkhttps://string-db.org/network/71421.HI_1371Desulfoviridin gamma subunit, putative; Could be part of a sulfur-relay system; Belongs to the DsrC/TusE family.
ttcA protein networkhttps://string-db.org/network/71421.HI_1371.1Conserved hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cystei [...]
mukF protein networkhttps://string-db.org/network/71421.HI_1372Killing protein (kicB); Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of [...]
mukE protein networkhttps://string-db.org/network/71421.HI_1373Killing protein suppressor (kicA); Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from bot [...]
mukB protein networkhttps://string-db.org/network/71421.HI_1374Cell division protein (mukB); Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Invol [...]
HI_1375 protein networkhttps://string-db.org/network/71421.HI_1375Predicted coding region HI1375; Hypothetical protein; identified by GeneMark; putative.
HI_1376 protein networkhttps://string-db.org/network/71421.HI_1376Predicted coding region HI1376; Hypothetical protein; identified by GeneMark; putative.
sbcB protein networkhttps://string-db.org/network/71421.HI_1377Exodeoxyribonuclease I (sbcB); Degrades single-stranded DNA (ssDNA) in a highly processive manner. Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties [...]
phoR protein networkhttps://string-db.org/network/71421.HI_1378Phosphate regulon sensor protein (phoR); Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated pro [...]
phoB protein networkhttps://string-db.org/network/71421.HI_1379Phosphate regulon transcriptional regulatory protein (phoB); This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR [...]
pstA protein networkhttps://string-db.org/network/71421.HI_1381Phosphate ABC transporter, permease protein (pstA); Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the me [...]
pstC protein networkhttps://string-db.org/network/71421.HI_1382Phosphate ABC transporter, permease protein (pstC); Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the me [...]
pstS protein networkhttps://string-db.org/network/71421.HI_1383Phosphate ABC transporter, periplasmic-binding protein (pstS); Part of the ABC transporter complex PstSACB involved in phosphate import.
ftnA protein networkhttps://string-db.org/network/71421.HI_1384Ferritin (rsgA); Iron-storage protein; Belongs to the ferritin family. Prokaryotic subfamily.
ftnB protein networkhttps://string-db.org/network/71421.HI_1385Ferritin (rsgA); Similar to SP:P23887 GB:X53513 PID:42898 GB:U00096 PID:1736567 percent identity: 57.32; identified by sequence similarity; putative.
HI_1386 protein networkhttps://string-db.org/network/71421.HI_1386Predicted coding region HI1386; Hypothetical protein; identified by GeneMark; putative.
trpE protein networkhttps://string-db.org/network/71421.HI_1387Anthranilate synthase component I (trpE); Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the [...]
trpG protein networkhttps://string-db.org/network/71421.HI_1388Anthranilate synthase component II (trpG); Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In th [...]
HI_1388.1 protein networkhttps://string-db.org/network/71421.HI_1388.1Predicted coding region HI1388.1; Brute Force ORF; identified by GeneMark; putative.
trpD protein networkhttps://string-db.org/network/71421.HI_1389Anthanilate phosphoribosyltransferase (trpD); Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anth [...]
trpC protein networkhttps://string-db.org/network/71421.HI_1389.1Indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (trpC); Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction [...]
HI_1390 protein networkhttps://string-db.org/network/71421.HI_1390Hydrogenase formation protein (hypG); Similar to SP:P37185 GB:U09177 PID:544489 PID:882519 GB:U00096 percent identity: 63.16; identified by sequence similarity; putative.
valS protein networkhttps://string-db.org/network/71421.HI_1391valyl-tRNA synthetase (valS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such [...]
hindIIIM protein networkhttps://string-db.org/network/71421.HI_1392Modification methylase (hindIIIM); This methylase recognizes the double-stranded sequence AAGCTT, causes specific methylation on A-1 on both strands, and protects the DNA from cleavage by the Hin [...]
hindIIIR protein networkhttps://string-db.org/network/71421.HI_1393Type II restriction endonuclease (hindIIIR); Recognizes the double-stranded sequence AAGCTT and cleaves after A-1.
HI_1394 protein networkhttps://string-db.org/network/71421.HI_1394Conserved hypothetical protein; Similar to PID:887850 GB:U00096 SP:Q46828 PID:1789267 percent identity: 68.32; identified by sequence similarity; putative; Belongs to the UPF0267 family.
HI_1395 protein networkhttps://string-db.org/network/71421.HI_1395Predicted coding region HI1395; Hypothetical protein; identified by GeneMark; putative.
HI_1396 protein networkhttps://string-db.org/network/71421.HI_1396Predicted coding region HI1396; Hypothetical protein; identified by GeneMark; putative.
holC protein networkhttps://string-db.org/network/71421.HI_1397DNA polymerase III, chi subunit (holC); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5 [...]
fumC protein networkhttps://string-db.org/network/71421.HI_1398Fumarate hydratase, class II (fumC); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase s [...]
HI_1399 protein networkhttps://string-db.org/network/71421.HI_1399Predicted coding region HI1399; Hypothetical protein; identified by GeneMark; putative.
HI_1400 protein networkhttps://string-db.org/network/71421.HI_1400Conserved hypothetical protein; Efficiently catalyzes the hydrolysis of the 3'-phosphate from 3',5'-bis-phosphonucleotides as well as the successive hydrolysis of 5'-phosphomononucleotides from t [...]
pyrD protein networkhttps://string-db.org/network/71421.HI_1401Dihydroorotate dehydrogenase (pyrD); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
HI_1402 protein networkhttps://string-db.org/network/71421.HI_1402Predicted coding region HI1402; Hypothetical protein; identified by GeneMark; putative.
HI_1403 protein networkhttps://string-db.org/network/71421.HI_1403Predicted coding region HI1403; Hypothetical protein; identified by GeneMark; putative.
HI_1404 protein networkhttps://string-db.org/network/71421.HI_1404Predicted coding region HI1404; Hypothetical protein; identified by GeneMark; putative.
HI_1405 protein networkhttps://string-db.org/network/71421.HI_1405Predicted coding region HI1405; Hypothetical protein; identified by GeneMark; putative.
HI_1406 protein networkhttps://string-db.org/network/71421.HI_1406Predicted coding region HI1406; Hypothetical protein; identified by GeneMark; putative.
HI_1407 protein networkhttps://string-db.org/network/71421.HI_1407traN-related protein; Similar to GB:L10330 PID:437700 percent identity: 40.17; identified by sequence similarity; putative; To E.coli plasmid IncP-alpha RP4 protein TraN.
HI_1409 protein networkhttps://string-db.org/network/71421.HI_1409Predicted coding region HI1409; Hypothetical protein; identified by GeneMark; putative.
HI_1410 protein networkhttps://string-db.org/network/71421.HI_1410Predicted coding region HI1410; Hypothetical protein; identified by GeneMark; putative.
HI_1411 protein networkhttps://string-db.org/network/71421.HI_1411Terminase, small subunit; Similar to SP:Q38627 PID:522116 percent identity: 32.31; identified by sequence similarity; putative.
HI_1412 protein networkhttps://string-db.org/network/71421.HI_1412Conserved hypothetical protein; Similar to SP:P21417 PID:1196685 percent identity: 31.79; identified by sequence similarity; putative.
HI_1413 protein networkhttps://string-db.org/network/71421.HI_1413Predicted coding region HI1413; Hypothetical protein; identified by GeneMark; putative.
HI_1414 protein networkhttps://string-db.org/network/71421.HI_1414Predicted coding region HI1414; Hypothetical protein; identified by GeneMark; putative.
HI_1415 protein networkhttps://string-db.org/network/71421.HI_1415Predicted coding region HI1415; Hypothetical protein; identified by GeneMark; putative; Belongs to the glycosyl hydrolase 19 family.
HI_1416 protein networkhttps://string-db.org/network/71421.HI_1416Predicted coding region HI1416; Hypothetical protein; identified by GeneMark; putative.
HI_1419 protein networkhttps://string-db.org/network/71421.HI_1419Predicted coding region HI1419; Hypothetical protein; identified by GeneMark; putative.
HI_1420 protein networkhttps://string-db.org/network/71421.HI_1420Predicted coding region HI1420; Hypothetical protein; identified by GeneMark; putative.
HI_1421 protein networkhttps://string-db.org/network/71421.HI_1421Predicted coding region HI1421; Hypothetical protein; identified by GeneMark; putative.
HI_1422 protein networkhttps://string-db.org/network/71421.HI_1422Predicted coding region HI1422; Hypothetical protein; identified by GeneMark; putative.
HI_1423 protein networkhttps://string-db.org/network/71421.HI_1423Predicted coding region HI1423; Hypothetical protein; identified by GeneMark; putative.
HI_1424 protein networkhttps://string-db.org/network/71421.HI_1424Integrase/recombinase, putative; Similar to SP:P10487 GB:D90039 SP:P16470 GB:X05022 GB:X12577 percent identity: 31.10; identified by sequence similarity; putative; Belongs to the 'phage' integras [...]
fnr protein networkhttps://string-db.org/network/71421.HI_1425Fumarate (and nitrate) reduction regulatory protein (fnr); It is involved in the activation of genes necessary for anaerobic respiration.
uspE protein networkhttps://string-db.org/network/71421.HI_1426Conserved hypothetical protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.
HI_1427 protein networkhttps://string-db.org/network/71421.HI_1427Predicted coding region HI1427; Hypothetical protein; identified by GeneMark; putative.
purN protein networkhttps://string-db.org/network/71421.HI_1428Phosphoribosylglycinamide formyltransferase (purN); Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N- [...]
purM protein networkhttps://string-db.org/network/71421.HI_1429Phosphoribosylaminoimidazole synthetase (purM); Similar to GB:M13747 SP:P08178 PID:147425 GB:U00096 PID:1788845 percent identity: 76.30; identified by sequence similarity; putative.
HI_1430 protein networkhttps://string-db.org/network/71421.HI_1430Short chain dehydrogenase/reductase; Similar to GB:U00096 PID:1787820 percent identity: 58.13; identified by sequence similarity; putative; Belongs to the short-chain dehydrogenases/reductases (S [...]
trpB protein networkhttps://string-db.org/network/71421.HI_1431Tryptophan synthase beta subunit (trpB); The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpA protein networkhttps://string-db.org/network/71421.HI_1432Tryptophan synthase alpha subunit (trpA); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
usg protein networkhttps://string-db.org/network/71421.HI_1433Usg-1 protein (usg1); Similar to SP:P08390 GB:X02743 PID:147125 PID:41717 GB:U00096 percent identity: 32.71; identified by sequence similarity; putative; Belongs to the aspartate-semialdehyde deh [...]
ybaK protein networkhttps://string-db.org/network/71421.HI_1434Transcriptional regulator, putative; Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity. Probably compensates for the lack of [...]
cspD protein networkhttps://string-db.org/network/71421.HI_1434.1Cold shock-like protein (cspD); Similar to SP:P24245 GB:U00096 PID:1651400 PID:1787107 percent identity: 68.66; identified by sequence similarity; putative.
HI_1434.2 protein networkhttps://string-db.org/network/71421.HI_1434.2Conserved hypothetical protein; Similar to GB:U00096 PID:1788113 percent identity: 65.12; identified by sequence similarity; putative; Belongs to the UPF0181 family.
truC protein networkhttps://string-db.org/network/71421.HI_1435Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil-65 in transfer RNAs; Belongs to the pseudouridine synthase RluA family.
HI_1436 protein networkhttps://string-db.org/network/71421.HI_1436Conserved hypothetical protein; Similar to PID:882688 GB:U00096 PID:882687 percent identity: 33.65; identified by sequence similarity; putative; To the N-terminal of E.carotovora exoenzyme regula [...]
HI_1436.2 protein networkhttps://string-db.org/network/71421.HI_1436.2Predicted coding region HI1436.2; Hypothetical protein; identified by GeneMark; putative.
xseB protein networkhttps://string-db.org/network/71421.HI_1437Exodeoxyribonuclease, small subunit (xseB); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligo [...]
ispA protein networkhttps://string-db.org/network/71421.HI_1438Geranyltranstransferase (ispA); Similar to GB:D00694 SP:P22939 PID:216584 GB:U00096 PID:1773105 percent identity: 53.56; identified by sequence similarity; putative.
dxs protein networkhttps://string-db.org/network/71421.HI_14391-deoxyxylulose-5-phosphate synthase (dxs) {Escherichia coli); Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- x [...]
sspB protein networkhttps://string-db.org/network/71421.HI_1440Stringent starvation protein B (sspB); Enhances recognition of ssrA-tagged proteins by the ClpX-ClpP protease; the ssrA degradation tag (AANDENYALAA) is added trans- translationally to proteins t [...]
sspA protein networkhttps://string-db.org/network/71421.HI_1441Stringent starvation protein A (sspA); Forms an equimolar complex with the RNA polymerase holoenzyme (RNAP) but not with the core enzyme.
rpsI protein networkhttps://string-db.org/network/71421.HI_1442Ribosomal protein S9 (rpS9); Similar to GB:S75161 SP:P31782 PID:241867 percent identity: 94.62; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS9 family.
rplM protein networkhttps://string-db.org/network/71421.HI_1443Ribosomal protein L13 (rpL13); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early st [...]
metF protein networkhttps://string-db.org/network/71421.HI_14445,10 methylenetetrahydrofolate reductase (metF); Similar to GB:L19201 SP:P00394 GB:V01502 PID:305044 PID:42000 percent identity: 73.10; identified by sequence similarity; putative; Belongs to the [...]
bioD1 protein networkhttps://string-db.org/network/71421.HI_1445Dethiobiotin synthase (bioD-1); Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to for [...]
HI_1446 protein networkhttps://string-db.org/network/71421.HI_1446Conserved hypothetical protein; Similar to GB:U00096 PID:1787427 percent identity: 41.67; identified by sequence similarity; putative.
folE protein networkhttps://string-db.org/network/71421.HI_1447GTP cyclohydrolase I (folE); Similar to GB:U00007 SP:P27511 GB:X63910 PID:312964 PID:405902 percent identity: 63.93; identified by sequence similarity; putative.
moeA protein networkhttps://string-db.org/network/71421.HI_1448Molybdopterin biosynthesis protein (moeA); Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP; Belongs to the MoeA family.
moeB protein networkhttps://string-db.org/network/71421.HI_1449Molybdopterin biosynthesis protein (moeB); Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein MoaD; Belongs to the HesA/MoeB/ThiF family.
HI_1450 protein networkhttps://string-db.org/network/71421.HI_1450Conserved hypothetical protein; Similar to GB:U00096 PID:1787501 percent identity: 48.65; identified by sequence similarity; putative; Belongs to the UPF0263 family.
HI_1452 protein networkhttps://string-db.org/network/71421.HI_1452Predicted coding region HI1452; Mediates export of lysine; Belongs to the LysO family.
HI_1453 protein networkhttps://string-db.org/network/71421.HI_1453Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 30.84; identified by sequence similarity; putative; Belongs to the thioredoxin family.
HI_1454 protein networkhttps://string-db.org/network/71421.HI_1454Cytochrome C-type biogenesis protein; Could be involved in cytochrome c synthesis; Belongs to the DsbD family.
msrAB protein networkhttps://string-db.org/network/71421.HI_1455Peptide methionine sulfoxide reductase (msrA); Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of m [...]
HI_1456 protein networkhttps://string-db.org/network/71421.HI_1456Predicted coding region HI1456; Hypothetical protein; identified by GeneMark; putative.
HI_1457 protein networkhttps://string-db.org/network/71421.HI_1457Opacity protein, putative; Similar to PID:2367659 percent identity: 34.32; identified by sequence similarity; putative; Belongs to the opacity porin family.
HI_1458 protein networkhttps://string-db.org/network/71421.HI_1458Predicted coding region HI1458; Hypothetical protein; identified by GeneMark; putative.
HI_1459 protein networkhttps://string-db.org/network/71421.HI_1459Sigma factor, putative; Similar to GB:AL009126 percent identity: 26.75; identified by sequence similarity; putative; Belongs to the sigma-70 factor family. ECF subfamily.
HI_1462 protein networkhttps://string-db.org/network/71421.HI_1462Conserved hypothetical protein; Similar to GB:U00096 SP:P77211 PID:1778487 PID:1786785 percent identity: 24.32; identified by sequence similarity; putative; Belongs to the outer membrane factor ( [...]
HI_1462.1 protein networkhttps://string-db.org/network/71421.HI_1462.1Predicted coding region HI1462.1; Hypothetical protein; identified by GeneMark; putative.
HI_1462.2 protein networkhttps://string-db.org/network/71421.HI_1462.2Conserved hypothetical protein; Similar to GB:U00096 PID:1788681 percent identity: 40.26; identified by sequence similarity; putative.
HI_1463 protein networkhttps://string-db.org/network/71421.HI_1463mrsA protein (mrsA); Similar to GB:L12968 SP:P31120 GB:U01376 PID:290443 PID:606114 percent identity: 73.26; identified by sequence similarity; putative.
HI_1464 protein networkhttps://string-db.org/network/71421.HI_1464Dihydropteroate synthase (folP-2); Similar to GB:L06494 SP:P26282 GB:U01376 GB:X68776 GB:X68777 percent identity: 54.15; identified by sequence similarity; putative.
HI_1465 protein networkhttps://string-db.org/network/71421.HI_1465Cell division ftsH-related protein; Similar to GB:M83138 SP:P28691 GB:U01376 PID:146028 PID:606116 percent identity: 77.66; identified by sequence similarity; putative; In the C-terminal section; [...]
HI_1466 protein networkhttps://string-db.org/network/71421.HI_1466Predicted coding region HI1466; Hypothetical protein; identified by GeneMark; putative.
HI_1466.1 protein networkhttps://string-db.org/network/71421.HI_1466.1Predicted coding region HI1466.1; Brute Force ORF; identified by GeneMark; putative; Belongs to the TonB-dependent receptor family.
HI_1467 protein networkhttps://string-db.org/network/71421.HI_1467ABC transporter, ATP-binding protein; Similar to SP:Q50614 PID:1483552 percent identity: 36.97; identified by sequence similarity; putative.
HI_1468 protein networkhttps://string-db.org/network/71421.HI_1468Ribosomal protein S15 (rpS15); Similar to GB:J02638 SP:P02371 GB:M14425 GB:X00761 GB:X01073 percent identity: 80.90; identified by sequence similarity; putative.
HI_1469 protein networkhttps://string-db.org/network/71421.HI_1469Predicted coding region HI1469; Hypothetical protein; identified by GeneMark; putative.
HI_1470 protein networkhttps://string-db.org/network/71421.HI_1470Iron chelatin ABC transporter, ATP-binding protein, putative; Similar to GB:AE000511 SP:O05732 PID:2072456 PID:2314024 percent identity: 38.60; identified by sequence similarity; putative.
HI_1471 protein networkhttps://string-db.org/network/71421.HI_1471Iron chelatin ABC transporter, permease protein, putative; Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the me [...]
HI_1472 protein networkhttps://string-db.org/network/71421.HI_1472Iron chelatin ABC transporter, periplasmic-binding protein, putative; Similar to GB:AE000511 PID:2314746 percent identity: 25.44; identified by sequence similarity; putative.
modD protein networkhttps://string-db.org/network/71421.HI_1473Molybdenum transport system protein (modD); Similar to SP:P94777 PID:1816657 percent identity: 43.21; identified by sequence similarity; putative; Belongs to the NadC/ModD family.
HI_1474 protein networkhttps://string-db.org/network/71421.HI_1474ABC transporter, ATP-binding protein; Similar to GB:AE000511 PID:2313950 percent identity: 38.71; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
HI_1475 protein networkhttps://string-db.org/network/71421.HI_1475Predicted coding region HI1475; Hypothetical protein; identified by GeneMark; putative.
HI_1476 protein networkhttps://string-db.org/network/71421.HI_1476Transcriptional regulatory protein; Similar to SP:Q37906 PID:403436 percent identity: 28.43; identified by sequence similarity; putative.
nlp protein networkhttps://string-db.org/network/71421.HI_1477DNA-binding protein (ner); Negative regulator of transcription starting from the Pe and Pc promoters of Mu. Also negatively regulates its own gene transcription (By similarity).
HI_1478 protein networkhttps://string-db.org/network/71421.HI_1478Transposase (muA); This transposase is essential for integration, replication- transposition, and excision of Mu-like viral DNA.
HI_1479 protein networkhttps://string-db.org/network/71421.HI_1479Predicted coding region HI1479; Hypothetical protein; identified by GeneMark; putative.
HI_1480 protein networkhttps://string-db.org/network/71421.HI_1480Predicted coding region HI1480; Hypothetical protein; identified by GeneMark; putative.
HI_1481 protein networkhttps://string-db.org/network/71421.HI_1481DNA transposition protein (muB); This protein is a non-specific DNA-binding and ATP- hydrolyzing protein essential for bacteriophage integration and replication.
HI_1482 protein networkhttps://string-db.org/network/71421.HI_1482Predicted coding region HI1482; Hypothetical protein; identified by GeneMark; putative.
HI_1483 protein networkhttps://string-db.org/network/71421.HI_1483Host-nuclease inhibitor protein (gam); Protects linear double-stranded DNA of Mu genome from exonuclease degradation.
HI_1484 protein networkhttps://string-db.org/network/71421.HI_1484Predicted coding region HI1484; Hypothetical protein; identified by GeneMark; putative.
HI_1485 protein networkhttps://string-db.org/network/71421.HI_1485Predicted coding region HI1485; Hypothetical protein; identified by GeneMark; putative.
HI_1486 protein networkhttps://string-db.org/network/71421.HI_1486Predicted coding region HI1486; Hypothetical protein; identified by GeneMark; putative.
HI_1487 protein networkhttps://string-db.org/network/71421.HI_1487Predicted coding region HI1487; Hypothetical protein; identified by GeneMark; putative.
HI_1488 protein networkhttps://string-db.org/network/71421.HI_1488E16 protein, putative; Similar to PID:215574 percent identity: 29.53; identified by sequence similarity; putative; To phage Mu protein gp16.
HI_1489 protein networkhttps://string-db.org/network/71421.HI_1489Predicted coding region HI1489; Hypothetical protein; identified by GeneMark; putative.
HI_1490 protein networkhttps://string-db.org/network/71421.HI_1490Positive regulator of late transcription {Bacteriophage mu); Similar to SP:P06022 PID:15812 PID:215521 PID:215582 percent identity: 44.26; identified by sequence similarity; putative.
HI_1491 protein networkhttps://string-db.org/network/71421.HI_1491DNA-binding protein, putative; Required for transcription of the phage late genes.
HI_1492 protein networkhttps://string-db.org/network/71421.HI_1492Predicted coding region HI1492; Hypothetical protein; identified by GeneMark; putative.
HI_1493 protein networkhttps://string-db.org/network/71421.HI_1493Predicted coding region HI1493; Hypothetical protein; identified by GeneMark; putative.
HI_1494 protein networkhttps://string-db.org/network/71421.HI_1494N-acetylmuramoyl-L-alanine amidase; Similar to SP:P20331 PID:15695 percent identity: 43.88; identified by sequence similarity; putative; To phage T3 and T7 N-acetylmuramoyl-L-alanine amidases.
HI_1495 protein networkhttps://string-db.org/network/71421.HI_1495Predicted coding region HI1495; Hypothetical protein; identified by GeneMark; putative.
HI_1496 protein networkhttps://string-db.org/network/71421.HI_1496Predicted coding region HI1496; Hypothetical protein; identified by GeneMark; putative.
HI_1497 protein networkhttps://string-db.org/network/71421.HI_1497Conserved hypothetical protein; Similar to SP:Q06424 PID:288658 percent identity: 36.21; identified by sequence similarity; putative.
HI_1498 protein networkhttps://string-db.org/network/71421.HI_1498Predicted coding region HI1498; Hypothetical protein; identified by GeneMark; putative.
HI_1498.1 protein networkhttps://string-db.org/network/71421.HI_1498.1Predicted coding region HI1498.1; Brute Force ORF; identified by GeneMark; putative.
HI_1499 protein networkhttps://string-db.org/network/71421.HI_1499Predicted coding region HI1499; Hypothetical protein; identified by GeneMark; putative; To phage Mu protein gp27.
HI_1500 protein networkhttps://string-db.org/network/71421.HI_1500Predicted coding region HI1500; Hypothetical protein; identified by GeneMark; putative; To phage Mu protein gp28.
HI_1501 protein networkhttps://string-db.org/network/71421.HI_1501Predicted coding region HI1501; Hypothetical protein; identified by GeneMark; putative; To phage Mu protein gp29.
HI_1502 protein networkhttps://string-db.org/network/71421.HI_1502Predicted coding region HI1502; Involved in virion morphogenesis.
HI_1503 protein networkhttps://string-db.org/network/71421.HI_1503G protein (muG-1); Similar to SP:Q01261 PID:215535 percent identity: 38.30; identified by sequence similarity; putative; To phage Mu protein G.
HI_1504 protein networkhttps://string-db.org/network/71421.HI_1504I protein (muI); Potential protease involved in virion morphogenesis.
HI_1505 protein networkhttps://string-db.org/network/71421.HI_1505Predicted coding region HI1505; Hypothetical protein; identified by GeneMark; putative; To phage Mu protein T.
HI_1506 protein networkhttps://string-db.org/network/71421.HI_1506Predicted coding region HI1506; Hypothetical protein; identified by GeneMark; putative.
HI_1507 protein networkhttps://string-db.org/network/71421.HI_1507Predicted coding region HI1507; Hypothetical protein; identified by GeneMark; putative.
HI_1508 protein networkhttps://string-db.org/network/71421.HI_1508Conserved hypothetical protein; Similar to PID:2353778 percent identity: 80.53; identified by sequence similarity; putative; To phage Mu protein gp36.
HI_1509 protein networkhttps://string-db.org/network/71421.HI_1509Conserved hypothetical protein; Similar to PID:2353777 percent identity: 79.75; identified by sequence similarity; putative; To phage Mu protein gp37.
HI_1510 protein networkhttps://string-db.org/network/71421.HI_1510Conserved hypothetical protein; Similar to GP:1834290 percent identity: 44.64; identified by sequence similarity; putative; To phage Mu protein gp38.
HI_1511 protein networkhttps://string-db.org/network/71421.HI_1511Sheath protein gpL (muL); Major component of the tail.
HI_1512 protein networkhttps://string-db.org/network/71421.HI_1512Conserved hypothetical protein; Similar to PID:1834292 percent identity: 38.79; identified by sequence similarity; putative; To phage Mu protein M.
HI_1513 protein networkhttps://string-db.org/network/71421.HI_1513Conserved hypothetical protein; Similar to PID:1834293 percent identity: 50.89; identified by sequence similarity; putative; To phage Mu protein gp41.
HI_1514 protein networkhttps://string-db.org/network/71421.HI_1514Predicted coding region HI1514; Hypothetical protein; identified by GeneMark; putative.
HI_1515 protein networkhttps://string-db.org/network/71421.HI_151564 kDa virion protein (muN); Similar to SP:P08557 PID:15105 percent identity: 31.48; identified by sequence similarity; putative; To phage Mu protein N.
HI_1518 protein networkhttps://string-db.org/network/71421.HI_1518Predicted coding region HI1518; Hypothetical protein; identified by GeneMark; putative; To phage Mu protein gp45.
HI_1519 protein networkhttps://string-db.org/network/71421.HI_1519Predicted coding region HI1519; Hypothetical protein; identified by GeneMark; putative; To phage Mu protein gp46.
HI_1520 protein networkhttps://string-db.org/network/71421.HI_1520Conserved hypothetical protein; Similar to GB:U00096 PID:1787398 percent identity: 33.47; identified by sequence similarity; putative; Belongs to the Mu gp47/PBSX XkdT family.
HI_1521 protein networkhttps://string-db.org/network/71421.HI_1521Conserved hypothetical protein; Similar to GB:U00096 PID:1787399 percent identity: 27.37; identified by sequence similarity; putative; To phage Mu protein gp48 an E.coli YmfQ.
HI_1522 protein networkhttps://string-db.org/network/71421.HI_1522Predicted coding region HI1522; Hypothetical protein; identified by GeneMark; putative; To phage Mu protein S.
HI_1522.1 protein networkhttps://string-db.org/network/71421.HI_1522.1Predicted coding region HI1522.1; Hypothetical protein; identified by GeneMark; putative; Belongs to the com family.
HI_1523 protein networkhttps://string-db.org/network/71421.HI_1523Predicted coding region HI1523; Hypothetical protein; identified by GeneMark; putative.
HI_1524 protein networkhttps://string-db.org/network/71421.HI_1524Predicted coding region HI1524; Hypothetical protein; identified by GeneMark; putative.
HI_1525 protein networkhttps://string-db.org/network/71421.HI_1525Molybdate-binding periplasmic protein, putative; Probably involved in the binding-dependent system; Belongs to the bacterial solute-binding protein ModA family.
hldE protein networkhttps://string-db.org/network/71421.HI_1526ADP-heptose synthase (rfaE); Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In t [...]
lpxL protein networkhttps://string-db.org/network/71421.HI_1527Lipid A biosynthesis lauroyl acyltransferase (htrB); Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
parE protein networkhttps://string-db.org/network/71421.HI_1528Topoisomerase IV, subunit B (parE); Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a cir [...]
parC protein networkhttps://string-db.org/network/71421.HI_1529Topoisomerase IV, subunit A (parC); Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a cir [...]
gltS protein networkhttps://string-db.org/network/71421.HI_1530Glutamate permease (gltS); Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
rimK protein networkhttps://string-db.org/network/71421.HI_1531Ribosomal protein S6 modification protein (rimK); Similar to SP:P17116 GB:X15859 PID:42747 GB:U00096 PID:1651386 percent identity: 45.55; identified by sequence similarity; putative.
grxA protein networkhttps://string-db.org/network/71421.HI_1532Glutaredoxin (grx); Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity).
fabB protein networkhttps://string-db.org/network/71421.HI_1533beta-ketoacyl-ACP synthase I (fabB); Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from [...]
HI_1534 protein networkhttps://string-db.org/network/71421.HI_1534Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 32.57; identified by sequence similarity; putative.
mnmC protein networkhttps://string-db.org/network/71421.HI_1535Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-depend [...]
HI_1536 protein networkhttps://string-db.org/network/71421.HI_1536Conserved hypothetical protein; Similar to GB:U00096 PID:1788664 percent identity: 50.93; identified by sequence similarity; putative.
licA protein networkhttps://string-db.org/network/71421.HI_1537Lic-1 operon protein (licA); Mediates phase variation of the LPS epitopes. Phase variation of H.influenza LPS epitopes expressed by LicA is determined by a translational switch (By similarity).
licB protein networkhttps://string-db.org/network/71421.HI_1538Lic-1 operon protein (licB); Similar to GB:M27280 SP:P14182 percent identity: 99.01; identified by sequence similarity; putative.
licC protein networkhttps://string-db.org/network/71421.HI_1539Lic-1 operon protein (licC); Similar to GB:M27280 SP:P14183 percent identity: 96.46; identified by sequence similarity; putative.
licD protein networkhttps://string-db.org/network/71421.HI_1540Lic-1 operon protein (licD); Transfers phosphorylcholine (ChoP) from choline diphosphonucleoside to the lipopolysaccharide (LPS). Belongs to the LicD transferase family.
sppA protein networkhttps://string-db.org/network/71421.HI_1541Protease IV (sppA); Digests cleaved signal peptides in vitro, its in vivo function is unknown. This activity is necessary to maintain proper secretion of mature proteins across the membrane (By s [...]
HI_1542 protein networkhttps://string-db.org/network/71421.HI_1542Conserved hypothetical protein; Similar to PID:2253239 percent identity: 50.27; identified by sequence similarity; putative; Belongs to the nitroreductase family.
HI_1543 protein networkhttps://string-db.org/network/71421.HI_1543Conserved hypothetical protein; Similar to GB:U00096 SP:P75915 PID:1787272 percent identity: 39.78; identified by sequence similarity; putative; Belongs to the TorD/DmsD family.
HI_1544 protein networkhttps://string-db.org/network/71421.HI_1544NAD(P)H oxidoreductase, putative; Similar to SP:Q64669 PID:595518 percent identity: 35.87; identified by sequence similarity; putative; Belongs to the NAD(P)H dehydrogenase (quinone) family.
sstT protein networkhttps://string-db.org/network/71421.HI_1545Sodium:dicarboxylate symporter protein; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino ac [...]
HI_1546 protein networkhttps://string-db.org/network/71421.HI_1546impA protein, putative; Similar to percent identity: 34.26; identified by sequence similarity; putative; Belongs to the peptidase S24 family.
aroG protein networkhttps://string-db.org/network/71421.HI_1547Phospho-2-dehydro-3-deoxyheptonate aldolase (phenylalanine repressible) (aroG); Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D [...]
lolE protein networkhttps://string-db.org/network/71421.HI_1548Conserved hypothetical transmembrane protein; Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. [...]
lolD protein networkhttps://string-db.org/network/71421.HI_1549ABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the perip [...]
bioD2 protein networkhttps://string-db.org/network/71421.HI_1550Dethiobiotin synthase (bioD-2); Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to for [...]
bioC protein networkhttps://string-db.org/network/71421.HI_1551Biotin synthesis protein, putative; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to syn [...]
HI_1552 protein networkhttps://string-db.org/network/71421.HI_1552Predicted coding region HI1552; Hypothetical protein; identified by GeneMark; putative.
bioF protein networkhttps://string-db.org/network/71421.HI_15538-amino-7-oxononanoate synthase (bioF); Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein [...]
bioA protein networkhttps://string-db.org/network/71421.HI_1554Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (bioA); Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to f [...]
lolC protein networkhttps://string-db.org/network/71421.HI_1555Conserved hypothetical transmembrane protein; Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. [...]
HI_1556 protein networkhttps://string-db.org/network/71421.HI_15562-hydroxyacid dehydrogenase; Similar to GB:AE000511 PID:2313177 percent identity: 41.64; identified by sequence similarity; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase [...]
kdsA protein networkhttps://string-db.org/network/71421.HI_15572-dehydro-3-deoxyphosphooctonate aldolase (kdsA); Similar to SP:P17579 GB:X05552 PID:940498 PID:968934 GB:U00096 percent identity: 81.63; identified by sequence similarity; putative; Belongs to t [...]
HI_1558 protein networkhttps://string-db.org/network/71421.HI_1558Conserved hypothetical protein; Similar to SP:P20101 GB:X05552 PID:41872 PID:1008040 GB:U00096 percent identity: 40.83; identified by sequence similarity; putative; Belongs to the UPF0162 family.
prmC protein networkhttps://string-db.org/network/71421.HI_1559hemK protein (hemK); Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N [...]
HI_1560 protein networkhttps://string-db.org/network/71421.HI_1560Predicted coding region HI1560; Hypothetical protein; identified by GeneMark; putative.
prfA protein networkhttps://string-db.org/network/71421.HI_1561Peptide chain release factor 1 (prfA); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
HI_1562 protein networkhttps://string-db.org/network/71421.HI_1562Predicted coding region HI1562; Hypothetical protein; identified by GeneMark; putative.
epmC protein networkhttps://string-db.org/network/71421.HI_1563Conserved hypothetical protein; Is involved in the final hydroxylation step of the post- translational modification of translation elongation factor P (EF-P) on 'Lys-34'. Acts after beta-lysylati [...]
HI_1564 protein networkhttps://string-db.org/network/71421.HI_1564Predicted coding region HI1564; Hypothetical protein; identified by GeneMark; putative.
HI_1564.1 protein networkhttps://string-db.org/network/71421.HI_1564.1Predicted coding region HI1564.1; Hypothetical protein; identified by GeneMark; putative.
HI_1565 protein networkhttps://string-db.org/network/71421.HI_1565Hemoglobin-binding protein; Similar to PID:1000292 PID:984513 percent identity: 54.76; identified by sequence similarity; putative.
HI_1567 protein networkhttps://string-db.org/network/71421.HI_1567TonB-dependent receptor, putative; Acts as a receptor for hemoglobin or the hemoglobin/haptoglobin complex of the human host and is required for heme uptake.
HI_1568 protein networkhttps://string-db.org/network/71421.HI_1568G protein (muG-2); Similar to SP:Q01261 PID:215535 percent identity: 33.33; identified by sequence similarity; putative; To phage Mu protein G.
HI_1569 protein networkhttps://string-db.org/network/71421.HI_1569Predicted coding region HI1569; Hypothetical protein; identified by GeneMark; putative.
HI_1570 protein networkhttps://string-db.org/network/71421.HI_1570Predicted coding region HI1570; Hypothetical protein; identified by GeneMark; putative.
HI_1571 protein networkhttps://string-db.org/network/71421.HI_1571Predicted coding region HI1571; Hypothetical protein; identified by GeneMark; putative.
pykA protein networkhttps://string-db.org/network/71421.HI_1573Pyruvate kinase, type II (pykA); Similar to GB:M63703 SP:P21599 GB:M87660 PID:147459 PID:146878 percent identity: 77.24; identified by sequence similarity; putative; Belongs to the pyruvate kinas [...]
dnaB protein networkhttps://string-db.org/network/71421.HI_1574Replicative DNA helicase (dnaB); Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP bind [...]
alr protein networkhttps://string-db.org/network/71421.HI_1575Alanine racemase, biosynthetic (alr); Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
pgi protein networkhttps://string-db.org/network/71421.HI_1576Glucose-6-phosphate isomerase (pgi); Similar to SP:P11537 GB:X15196 PID:396360 PID:42377 GB:U00096 percent identity: 77.05; identified by sequence similarity; putative.
HI_1577 protein networkhttps://string-db.org/network/71421.HI_1577IS1016-V6 protein, putative; Similar to GB:X59756 percent identity: 43.95; identified by sequence similarity; putative.
HI_1578 protein networkhttps://string-db.org/network/71421.HI_1578Glycosyl transferase, putative; Similar to PID:595813 percent identity: 47.32; identified by sequence similarity; putative; Belongs to the glycosyltransferase 2 family.
pcp protein networkhttps://string-db.org/network/71421.HI_157915 kDa peptidoglycan-associated lipoprotein (lpp); Similar to GB:M18877 SP:P10325 percent identity: 94.84; identified by sequence similarity; putative.
HI_1581 protein networkhttps://string-db.org/network/71421.HI_1581Conserved hypothetical protein; Similar to PID:1204257 SP:P52008 GB:U00096 PID:1788183 percent identity: 46.10; identified by sequence similarity; putative.
HI_1582 protein networkhttps://string-db.org/network/71421.HI_1582Conserved hypothetical protein; Similar to PID:1204257 SP:P52008 GB:U00096 PID:1788183 percent identity: 40.56; identified by sequence similarity; putative; To E.coli YecM.
argS protein networkhttps://string-db.org/network/71421.HI_1583arginyl-tRNA synthetase (argS); Similar to SP:P11875 GB:X15320 PID:581040 GB:U00096 PID:1736522 percent identity: 71.40; identified by sequence similarity; putative.
ilvH protein networkhttps://string-db.org/network/71421.HI_1584Acetolactate synthase III small subunit (ilvH); Similar to GB:D10483 SP:P00894 GB:X01609 PID:216495 PID:40846 percent identity: 65.62; identified by sequence similarity; putative; Belongs to the [...]
ilvI protein networkhttps://string-db.org/network/71421.HI_1585Acetolactate synthase III large subunit (ilvI); Similar to GB:D10483 SP:P00893 GB:X01609 PID:216494 PID:40845 percent identity: 70.80; identified by sequence similarity; putative.
HI_1586 protein networkhttps://string-db.org/network/71421.HI_1586Conserved hypothetical integral membrane protein; Similar to GB:AE000511 PID:2314087 percent identity: 36.21; identified by sequence similarity; putative.
hns protein networkhttps://string-db.org/network/71421.HI_1587DNA-binding protein H-NS (hns); A DNA-binding protein implicated in transcriptional repression and chromosome organization and compaction. Binds nucleation sites in AT-rich DNA and bridges them, [...]
purU protein networkhttps://string-db.org/network/71421.HI_1588Formyltetrahydrofolate deformylase (purU); Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
aroA protein networkhttps://string-db.org/network/71421.HI_15893-phosphoshikimate-1-carboxyvinyltransferase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enol [...]
rarA protein networkhttps://string-db.org/network/71421.HI_1590Conserved hypothetical protein; DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.
lolA protein networkhttps://string-db.org/network/71421.HI_1591Outer membrane lipoproteins carrier protein (lolA); Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the [...]
ftsK protein networkhttps://string-db.org/network/71421.HI_1592Cell division protein FtsK-related protein; May function as a DNA motor that moves dsDNA in an ATP- dependent manner towards the dif recombination site, which is located within the replication te [...]
HI_1593 protein networkhttps://string-db.org/network/71421.HI_1593Predicted coding region HI1593; Hypothetical protein; identified by GeneMark; putative.
HI_1594 protein networkhttps://string-db.org/network/71421.HI_1594Predicted coding region HI1594; Hypothetical protein; identified by GeneMark; putative.
HI_1595 protein networkhttps://string-db.org/network/71421.HI_1595Predicted coding region HI1595; Hypothetical protein; identified by GeneMark; putative.
lrp protein networkhttps://string-db.org/network/71421.HI_1596Leucine responsive regulatory protein (lrp); Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at leas [...]
radA protein networkhttps://string-db.org/network/71421.HI_1597DNA repair protein (radA); DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated stran [...]
HI_1598 protein networkhttps://string-db.org/network/71421.HI_1598Conserved hypothetical protein; Involved in the hydrolysis of the beta-gamma-phosphoanhydride linkage of triphosphate-containing substrates (inorganic or nucleoside- linked). Catalyzes the hydrol [...]
HI_1599 protein networkhttps://string-db.org/network/71421.HI_1599Predicted coding region HI1599; Hypothetical protein; identified by GeneMark; putative.
HI_1600 protein networkhttps://string-db.org/network/71421.HI_1600Predicted coding region HI1600; Hypothetical protein; identified by GeneMark; putative; Belongs to the UPF0276 family.
HI_1601 protein networkhttps://string-db.org/network/71421.HI_1601Predicted coding region HI1601; Hypothetical protein; identified by GeneMark; putative.
HI_1602 protein networkhttps://string-db.org/network/71421.HI_1602Predicted coding region HI1602; Hypothetical protein; identified by GeneMark; putative.
HI_1603 protein networkhttps://string-db.org/network/71421.HI_1603Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 28.84; identified by sequence similarity; putative; Belongs to the UPF0111 family.
HI_1604 protein networkhttps://string-db.org/network/71421.HI_1604Phosphate permease, putative; Potential transporter for phosphate; Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
HI_1605 protein networkhttps://string-db.org/network/71421.HI_1605Conserved hypothetical protein; Similar to SP:P39202 PID:1203798 GB:U00096 PID:1789435 percent identity: 40.72; identified by sequence similarity; putative.
cca protein networkhttps://string-db.org/network/71421.HI_1606tRNA nucleotidyltransferase (cca); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the [...]
lolB protein networkhttps://string-db.org/network/71421.HI_1607hemM protein (hemM); Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
ispE protein networkhttps://string-db.org/network/71421.HI_1608Conserved hypothetical protein; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
prs protein networkhttps://string-db.org/network/71421.HI_1609Phosphoribosylpyrophosphate synthetase (prsA); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from [...]
tyrS protein networkhttps://string-db.org/network/71421.HI_1610Tyrosyl tRNA synthetase (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor [...]
sfsA protein networkhttps://string-db.org/network/71421.HI_1611Sugar fermentation stimulation protein (sfsA); Similar to GB:D26562 SP:P18273 GB:M34945 GB:M60726 PID:145750 percent identity: 54.79; identified by sequence similarity; putative; Belongs to the S [...]
hmrM protein networkhttps://string-db.org/network/71421.HI_1612Conserved hypothetical transmembrane protein; Multidrug efflux pump that functions as a Na(+)/drug antiporter. Confers resistance to norfloxacin, acriflavine, doxorubicin, ethidium bromide, tetra [...]
ribE protein networkhttps://string-db.org/network/71421.HI_1613Riboflavin synthase, alpha chain (ribE); Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)ura [...]
pepN protein networkhttps://string-db.org/network/71421.HI_1614Aminopeptidase N (pepN); Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvatio [...]
purE protein networkhttps://string-db.org/network/71421.HI_1615Phosphoribosylaminoimidazole carboxylase, catalytic subunit (purE); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAI [...]
purK protein networkhttps://string-db.org/network/71421.HI_1616Phosphoribosylaminoimidazole carboxylase, ATPase subunit (purK); Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucl [...]
aspC protein networkhttps://string-db.org/network/71421.HI_1617Aspartate aminotransferase (aspC); Similar to SP:P00509 GB:X03629 GB:X05904 PID:41011 PID:41013 percent identity: 62.63; identified by sequence similarity; putative; Belongs to the class-I pyrido [...]
HI_1618 protein networkhttps://string-db.org/network/71421.HI_1618ABC transporter, ATP-binding protein; Similar to GB:AE000666 percent identity: 39.29; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
HI_1620 protein networkhttps://string-db.org/network/71421.HI_1620Predicted coding region HI1620; Hypothetical protein; identified by GeneMark; putative.
HI_1621 protein networkhttps://string-db.org/network/71421.HI_1621Conserved hypothetical protein; May be involved in metal transport; Belongs to the CbiM family.
HI_1622 protein networkhttps://string-db.org/network/71421.HI_1622Predicted coding region HI1622; Hypothetical protein; identified by GeneMark; putative.
zntR protein networkhttps://string-db.org/network/71421.HI_1623Mercuric resistance operon regulatory protein (merR2); Transcriptional regulator.
HI_1624 protein networkhttps://string-db.org/network/71421.HI_1624Predicted coding region HI1624; Hypothetical protein; identified by GeneMark; putative.
HI_1625 protein networkhttps://string-db.org/network/71421.HI_1625Predicted coding region HI1625; Hypothetical protein; identified by GeneMark; putative.
HI_1626 protein networkhttps://string-db.org/network/71421.HI_1626Conserved hypothetical protein; Similar to SP:P46909 PID:971339 GB:AL009126 percent identity: 34.62; identified by sequence similarity; putative.
HI_1627 protein networkhttps://string-db.org/network/71421.HI_1627Conserved hypothetical protein; Similar to PID:2407234 percent identity: 56.64; identified by sequence similarity; putative; Belongs to the RutC family.
HI_1628 protein networkhttps://string-db.org/network/71421.HI_1628Conserved hypothetical protein; Similar to SP:P39436 PID:606172 GB:U00096 PID:1789628 percent identity: 35.94; identified by sequence similarity; putative; To E.coli YhcB.
HI_1629 protein networkhttps://string-db.org/network/71421.HI_1629dedA protein, putative; Similar to GB:M68934 SP:P09548 GB:X02743 PID:146363 GB:U00096 percent identity: 30.38; identified by sequence similarity; putative.
rplY protein networkhttps://string-db.org/network/71421.HI_1630Ribosomal protein L25 (rpL25); This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL2 [...]
HI_1631 protein networkhttps://string-db.org/network/71421.HI_1631Predicted coding region HI1631; Hypothetical protein; identified by GeneMark; putative.
HI_1632 protein networkhttps://string-db.org/network/71421.HI_1632Predicted coding region HI1632; Hypothetical protein; identified by GeneMark; putative; Belongs to the aspartokinase family.
purA protein networkhttps://string-db.org/network/71421.HI_1633Adenylosuccinate synthetase (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belon [...]
dapD protein networkhttps://string-db.org/network/71421.HI_16342,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase (dapD); Similar to GB:X63201 SP:P41396 PID:38947 percent identity: 96.70; identified by sequence similarity; putative; Belongs to th [...]
purR protein networkhttps://string-db.org/network/71421.HI_1635Purine nucleotide synthesis repressor (purR); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN an [...]
ppc protein networkhttps://string-db.org/network/71421.HI_1636Phosphoenolpyruvate carboxylase (ppc); Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
HI_1637 protein networkhttps://string-db.org/network/71421.HI_1637Conserved hypothetical protein; Similar to GB:U00096 PID:1787581 percent identity: 50.00; identified by sequence similarity; putative; To E.coli YcjX.
sapA protein networkhttps://string-db.org/network/71421.HI_1638Peptide ABC transporter, periplasmic-binding protein (sapA); Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides; Belongs to the bacterial [...]
sapB protein networkhttps://string-db.org/network/71421.HI_1639Peptide ABC transporter, permease protein (sapB); Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides; Belongs to the binding-protein-depen [...]
sapC protein networkhttps://string-db.org/network/71421.HI_1640Peptide ABC transporter, permease protein (sapC); Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides; Belongs to the binding-protein-depen [...]
sapD protein networkhttps://string-db.org/network/71421.HI_1641Peptide ABC transporter, ATP-binding protein (sapD); Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides; Belongs to the ABC transporter su [...]
sapF protein networkhttps://string-db.org/network/71421.HI_1642Peptide ABC transporter, ATP-binding protein (sapF); Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides; Belongs to the ABC transporter su [...]
HI_1643 protein networkhttps://string-db.org/network/71421.HI_1643Conserved hypothetical protein; Similar to SP:P33019 PID:405879 GB:U00096 PID:1788482 percent identity: 52.91; identified by sequence similarity; putative.
truA protein networkhttps://string-db.org/network/71421.HI_1644Pseudouridylate synthase I (truA); Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
fbp protein networkhttps://string-db.org/network/71421.HI_1645Fructose-1,6-bisphosphatase (fbp); Similar to SP:P09200 GB:X12545 PID:41416 PID:537074 GB:U00096 percent identity: 70.48; identified by sequence similarity; putative.
cmk2 protein networkhttps://string-db.org/network/71421.HI_1646Cytidylate kinase 2 (cmkB); Similar to SP:P23863 PID:42839 GB:U00096 PID:1651431 PID:1651438 percent identity: 63.55; identified by sequence similarity; putative.
pdxS protein networkhttps://string-db.org/network/71421.HI_1647Conserved hypothetical protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT [...]
pdxT protein networkhttps://string-db.org/network/71421.HI_1648Conserved hypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled t [...]
dld protein networkhttps://string-db.org/network/71421.HI_1649D-lactate dehydrogenase (dld); Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.
HI_1650 protein networkhttps://string-db.org/network/71421.HI_1650Predicted coding region HI1650; Hypothetical protein; identified by GeneMark; putative.
HI_1651 protein networkhttps://string-db.org/network/71421.HI_1651Predicted coding region HI1651; Hypothetical protein; identified by GeneMark; putative.
nlpC protein networkhttps://string-db.org/network/71421.HI_1652Lipoprotein (spr); Similar to GB:U00096 SP:P77685 PID:1498150 PID:1736840 PID:1788501 percent identity: 58.18; identified by sequence similarity; putative.
rsmI protein networkhttps://string-db.org/network/71421.HI_1654Conserved hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
lpoA protein networkhttps://string-db.org/network/71421.HI_1655Antigen; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).
HI_1656 protein networkhttps://string-db.org/network/71421.HI_1656Conserved hypothetical protein; Similar to SP:P45465 PID:606088 GB:U00096 PID:1789538 percent identity: 48.67; identified by sequence similarity; putative; Belongs to the UPF0102 family.
HI_1657 protein networkhttps://string-db.org/network/71421.HI_1657Conserved hypothetical protein; Similar to SP:P45466 PID:606089 GB:U00096 PID:1789539 percent identity: 35.26; identified by sequence similarity; putative; Belongs to the SIS family. DiaA subfami [...]
HI_1658 protein networkhttps://string-db.org/network/71421.HI_1658Hemolysin, putative; Similar to SP:P45467 PID:606090 GB:U00096 PID:1789540 percent identity: 51.10; identified by sequence similarity; putative.
nrdA protein networkhttps://string-db.org/network/71421.HI_1659Ribonucleoside-diphosphate reductase, alpha chain (nrdA); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleo [...]
nrdB protein networkhttps://string-db.org/network/71421.HI_1660Ribonucleoside diphosphate reductase, beta chain (nrdB); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleot [...]
sucB protein networkhttps://string-db.org/network/71421.HI_16612-oxoglutarate dehydrogenase E2 component, dihydrolipoamide succinyltransferase(sucB); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conve [...]
sucA protein networkhttps://string-db.org/network/71421.HI_16622-oxoglutarate dehydrogenase E1 component (sucA); E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conv [...]
gloC protein networkhttps://string-db.org/network/71421.HI_1663Conserved hypothetical protein; Type II glyoxalase, isozyme of GloB, that hydrolyzes (R)-S- lactoylglutathione to (R)-lactate and glutathione. Plays a role in methylglyoxal (MG) detoxification.
HI_1664 protein networkhttps://string-db.org/network/71421.HI_1664Conserved hypothetical protein; Similar to GB:U00089 SP:P78005 PID:1673805 percent identity: 31.05; identified by sequence similarity; putative.
HI_1665 protein networkhttps://string-db.org/network/71421.HI_1665Predicted coding region HI1665; Hypothetical protein; identified by GeneMark; putative.
HI_1666 protein networkhttps://string-db.org/network/71421.HI_1666Conserved hypothetical protein; Similar to GB:U00096 SP:P75848 PID:1787157 percent identity: 49.73; identified by sequence similarity; putative.
HI_1667 protein networkhttps://string-db.org/network/71421.HI_1667Conserved hypothetical protein; Similar to SP:P22525 GB:X57550 PID:42044 GB:U00096 PID:1787155 percent identity: 42.12; identified by sequence similarity; putative; Belongs to the YkuD family.
prc protein networkhttps://string-db.org/network/71421.HI_1668Tail specific protease (prc); Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the [...]
HI_1669 protein networkhttps://string-db.org/network/71421.HI_1669Conserved hypothetical protein; Similar to SP:P45577 GB:U00096 percent identity: 51.35; identified by sequence similarity; putative.
proQ protein networkhttps://string-db.org/network/71421.HI_1670Predicted coding region HI1670; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.
HI_1671 protein networkhttps://string-db.org/network/71421.HI_1671Conserved hypothetical protein; Similar to GB:U00096 PID:1736474 PID:1736480 PID:1788137 percent identity: 43.04; identified by sequence similarity; putative.
HI_1672 protein networkhttps://string-db.org/network/71421.HI_1672Conserved hypothetical protein; Similar to GB:U00096 PID:1736475 PID:1736481 PID:1788138 percent identity: 42.94; identified by sequence similarity; putative.
moaE protein networkhttps://string-db.org/network/71421.HI_1673Molybdopterin converting factor, subunit 2 (moaE); Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithio [...]
moaD protein networkhttps://string-db.org/network/71421.HI_1674Molybdopterin converting factor, subunit 1 (moaD); Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin.
moaC protein networkhttps://string-db.org/network/71421.HI_1675Molybdenum cofactor biosynthesis protein C (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the Mo [...]
moaA protein networkhttps://string-db.org/network/71421.HI_1676Molybdenum cofactor biosynthesis protein A (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
HI_1677 protein networkhttps://string-db.org/network/71421.HI_1677Conserved hypothetical protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters; Belongs to the RIC family.
HI_1678 protein networkhttps://string-db.org/network/71421.HI_1678kpsF protein (kpsF); Catalyzes the reversible aldol-ketol isomerization between D- ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P). Belongs to the SIS family. GutQ/KpsF subfamily.
HI_1679 protein networkhttps://string-db.org/network/71421.HI_1679Conserved hypothetical protein; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
HI_1680 protein networkhttps://string-db.org/network/71421.HI_1680Conserved hypothetical transmembrane protein; Similar to GB:U00096 PID:1787194 percent identity: 38.90; identified by sequence similarity; putative.
HI_1681 protein networkhttps://string-db.org/network/71421.HI_1681Conserved hypothetical protein; Similar to GB:U00096 PID:1787198 percent identity: 26.85; identified by sequence similarity; putative; Belongs to the UPF0319 family.
sohB protein networkhttps://string-db.org/network/71421.HI_1682Protease, putative (sohB); Possible protease; Belongs to the peptidase S49 family.
rnfA protein networkhttps://string-db.org/network/71421.HI_1683Conserved hypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
rnfB protein networkhttps://string-db.org/network/71421.HI_1684Iron-sulfur cluster binding protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin [...]
rnfC protein networkhttps://string-db.org/network/71421.HI_1685Conserved hypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin fami [...]
rnfD protein networkhttps://string-db.org/network/71421.HI_1686Conserved hypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.
rnfG protein networkhttps://string-db.org/network/71421.HI_1687Nitrogen fixation protein (rnfG); Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.
rnfE protein networkhttps://string-db.org/network/71421.HI_1688Conserved hypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
nth protein networkhttps://string-db.org/network/71421.HI_1689Endonuclease III (nth); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving [...]
HI_1690 protein networkhttps://string-db.org/network/71421.HI_1690Sodium-dependent transporter, putative; Putative sodium-dependent transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
modC protein networkhttps://string-db.org/network/71421.HI_1691Molybdenum ABC transporter, ATP-binding protein (modC); Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs [...]
modB protein networkhttps://string-db.org/network/71421.HI_1692Molybdenum ABC transporter, permease protein (modB); Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the [...]
modA protein networkhttps://string-db.org/network/71421.HI_1693Molybdenum ABC transporter, periplasmic-binding protein (modA); Involved in the transport of molybdenum into the cell.
modE protein networkhttps://string-db.org/network/71421.HI_1694Molybdenum transport protein (modE); The ModE-Mo complex acts as a repressor of the modABC operon, involved in the transport of molybdate. Upon binding molybdate, the conformation of the protein [...]
HI_1695 protein networkhttps://string-db.org/network/71421.HI_1695Lipopolysaccharide biosynthesis protein, putative; Similar to PID:600434 SP:Q46635 percent identity: 45.38; identified by sequence similarity; putative; Belongs to the glycosyltransferase 2 famil [...]
HI_1696 protein networkhttps://string-db.org/network/71421.HI_1696Lipopolysaccharide biosynthesis protein, putative; Similar to PID:1944156 percent identity: 80.82; identified by sequence similarity; putative; Belongs to the glycosyltransferase 2 family.
HI_1697 protein networkhttps://string-db.org/network/71421.HI_1697Lipopolysaccharide biosynthesis protein, putative; Similar to GB:U05670 percent identity: 28.57; identified by sequence similarity; putative; Belongs to the glycosyltransferase 25 family.
HI_1698 protein networkhttps://string-db.org/network/71421.HI_1698Lipopolysaccharide biosynthesis protein; Similar to PID:633695 percent identity: 38.48; identified by sequence similarity; putative.
lsgB protein networkhttps://string-db.org/network/71421.HI_1699Lipopolysaccharide biosynthesis protein, putative; Catalyzes the transfer of sialic acid from the substrate CMP- N-acetylneuraminate to the terminal galactose residue of the N- acetyllactosamine [...]
HI_1700 protein networkhttps://string-db.org/network/71421.HI_1700Lipopolysaccharide biosynthesis protein, putative; Similar to GB:AE000666 percent identity: 23.40; identified by sequence similarity; putative.
HI_1701 protein networkhttps://string-db.org/network/71421.HI_1701Conserved hypothetical protein; Similar to PID:1652989 percent identity: 33.19; identified by sequence similarity; putative.
metE protein networkhttps://string-db.org/network/71421.HI_17025-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase (metE); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine forma [...]
lptG protein networkhttps://string-db.org/network/71421.HI_1703Conserved hypothetical protein; Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.
lptF protein networkhttps://string-db.org/network/71421.HI_1704Conserved hypothetical protein; Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.
pepA protein networkhttps://string-db.org/network/71421.HI_1705Aminopeptidase A/I (pepA); Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptid [...]
HI_1706 protein networkhttps://string-db.org/network/71421.HI_1706High-affinity choline transport protein (betT); Similar to SP:P17447 GB:X52905 PID:48716 GB:U00096 PID:1657512 percent identity: 34.72; identified by sequence similarity; putative.
qseC protein networkhttps://string-db.org/network/71421.HI_1707Sensor protein (ygiY); Member of a two-component regulatory system QseB/QseC. May activate QseB by phosphorylation (By similarity).
qseB protein networkhttps://string-db.org/network/71421.HI_1708Transcriptional regulatory protein (ygiX); Member of a two-component regulatory system QseB/QseC.
HI_1709 protein networkhttps://string-db.org/network/71421.HI_1709Conserved hypothetical protein; Similar to PID:882554 SP:P52083 GB:U00096 PID:1789401 percent identity: 39.20; identified by sequence similarity; putative.
HI_1710 protein networkhttps://string-db.org/network/71421.HI_1710Predicted coding region HI1710; Hypothetical protein; identified by GeneMark; putative.
crr protein networkhttps://string-db.org/network/71421.HI_1711PTS system, glucose-specific IIA component (crr); The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosph [...]
ptsI protein networkhttps://string-db.org/network/71421.HI_1712Phosphoenolpyruvate-protein phosphotransferase (ptsI); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohyd [...]
ptsH protein networkhttps://string-db.org/network/71421.HI_1713Phosphocarrier protein HPr (ptsH); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transpor [...]
rsgA protein networkhttps://string-db.org/network/71421.HI_1714Conserved hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May [...]
orn protein networkhttps://string-db.org/network/71421.HI_1715Conserved hypothetical protein; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
wecA protein networkhttps://string-db.org/network/71421.HI_1716Undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase (rfe), putative; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate [...]
HI_1717 protein networkhttps://string-db.org/network/71421.HI_1717Predicted coding region HI1717; Hypothetical protein; identified by GeneMark; putative.
HI_1718 protein networkhttps://string-db.org/network/71421.HI_1718Predicted coding region HI1718; Hypothetical protein; identified by GeneMark; putative.
glnD protein networkhttps://string-db.org/network/71421.HI_1719Uridylyl transferase (glnD); Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses throu [...]
HI_1720 protein networkhttps://string-db.org/network/71421.HI_1720Conserved hypothetical protein; Similar to GB:U09558 PID:495495 percent identity: 33.33; identified by sequence similarity; putative; Belongs to the IS150/IS1296 orfA family.
HI_1721 protein networkhttps://string-db.org/network/71421.HI_1721Transposase, putative; Similar to SP:P19769 GB:X07037 PID:581111 PID:912474 GB:U00096 percent identity: 54.55; identified by sequence similarity; putative; Belongs to the transposase IS3/IS150/IS [...]
map protein networkhttps://string-db.org/network/71421.HI_1722Methionine aminopeptidase (map); Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and u [...]
erpA protein networkhttps://string-db.org/network/71421.HI_1723Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG.
HI_1724 protein networkhttps://string-db.org/network/71421.HI_1724Conserved hypothetical protein; Similar to SP:P45567 GB:U00096 PID:1786310 percent identity: 38.98; identified by sequence similarity; putative; Belongs to the UPF0231 family.
mrcB protein networkhttps://string-db.org/network/71421.HI_1725Penicillin-binding protein 1B (ponB); Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-termina [...]
purC protein networkhttps://string-db.org/network/71421.HI_1726Phosphoribosylaminoimidazole-succinocarboxamide synthase (purC); Similar to PID:1144522 SP:Q59566 PID:1550658 percent identity: 46.67; identified by sequence similarity; putative; Belongs to the [...]
argG protein networkhttps://string-db.org/network/71421.HI_1727Argininosuccinate synthetase (argG); Similar to GB:M35236 SP:P22767 PID:145342 PID:606111 GB:U00096 percent identity: 79.04; identified by sequence similarity; putative; Belongs to the argininosu [...]
HI_1728 protein networkhttps://string-db.org/network/71421.HI_1728Conserved hypothetical protein; Similar to SP:P42965 PID:707085 PID:1805475 GB:AL009126 percent identity: 62.18; identified by sequence similarity; putative.
pxpA protein networkhttps://string-db.org/network/71421.HI_1729Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
pxpC protein networkhttps://string-db.org/network/71421.HI_1730Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
pxpB protein networkhttps://string-db.org/network/71421.HI_1731Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
rnb protein networkhttps://string-db.org/network/71421.HI_1733Exoribonuclease II (rnb); Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity).
fabI protein networkhttps://string-db.org/network/71421.HI_1734Enoyl-(acyl-carrier-protein) reductase (fabI); Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in th [...]
prfC protein networkhttps://string-db.org/network/71421.HI_1735Peptide chain release factor 3 (prfC); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preferenc [...]
HI_1736 protein networkhttps://string-db.org/network/71421.HI_1736Predicted coding region HI1736; Hypothetical protein; identified by GeneMark; putative.
HI_1737 protein networkhttps://string-db.org/network/71421.HI_1737Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 53.70; identified by sequence similarity; putative.
HI_1738 protein networkhttps://string-db.org/network/71421.HI_1738Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 51.29; identified by sequence similarity; putative.
metR protein networkhttps://string-db.org/network/71421.HI_1739Transcriptional activator (metR); Control of the last step in methionine biosynthesis; MetR is a positive activator of the metA, metE and metH genes; Belongs to the LysR transcriptional regulator [...]
lldD protein networkhttps://string-db.org/network/71421.HI_1739.1L-lactate dehydrogenase (lctD); Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
murI protein networkhttps://string-db.org/network/71421.HI_1739.2Glutamate racemase (murI); Provides the (R)-glutamate required for cell wall biosynthesis.
recG protein networkhttps://string-db.org/network/71421.HI_1740ATP-dependent DNA helicase (recG); Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwind [...]
spoT protein networkhttps://string-db.org/network/71421.HI_1741Guanosine-3',5'-bis(diphosphate) 3'- pyrophosphohydrolase (spoT); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety [...]
rpoZ protein networkhttps://string-db.org/network/71421.HI_1742DNA-directed RNA polymerase, omega chain (rpoZ); Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta a [...]
gmk protein networkhttps://string-db.org/network/71421.HI_1743Guanylate kinase (gmk); Essential for recycling GMP and indirectly, cGMP.