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Single Protein by Name / Identifier
Multiple Proteins by Names / Identifiers
Protein Pair by Name/Identifier
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Single / Multiple Proteins by Sequence
Proteins with Values/Ranks - Functional Enrichment Analysis
Submit your entire experiment as a list of proteins - no cutoffs.
Behind each protein, put a meaningful value for ranking (fold-change, log-pvalue, abundance, ...).
Behind each protein, put a meaningful value for ranking (fold-change, log-pvalue, abundance, ...).
Geneset by Pathway / Process / Disease / Publication
Search for any pathway name and visualize its proteins as a STRING network. You can query any identifier or a keyword matching, among others, Gene Ontology terms, KEGG pathways, and diseases, but also published manuscripts that may discuss groups of genes.
Organisms and Clades
Add any organism to STRING / Annotate proteome
Upload a complete species proteome to STRING, and we'll generate its interaction network and predict protein functions, including Gene Ontology terms and KEGG pathways. Once uploaded, you can explore and analyze your proteome data through our web interface, access it programmatically via API, or download all predictions in bulk.
Examples and Highlights
Example 1
FAA4 and its ten most confident interactors.
FAA4 in yeast is a long chain fatty acyl-CoA synthetase; see it connected to other synthetases as well as regulators.
FAA4 in yeast is a long chain fatty acyl-CoA synthetase; see it connected to other synthetases as well as regulators.
Example 2
The 20 most frequently mutated human cancer genes.
These have a higher-than-expected degree of interconnectivity, and are enriched in characteristic molecular functions.
These have a higher-than-expected degree of interconnectivity, and are enriched in characteristic molecular functions.
Example 3
A poorly characterized protein from Natronococcus.
It has no annotated domains or functions, but shows some intriguing connections to possible DNA-replication or -repair proteins.
It has no annotated domains or functions, but shows some intriguing connections to possible DNA-replication or -repair proteins.
Protein Family by Name
Protein Family by Protein Name
Protein Family by Protein Sequence
Protein Families by Multiple Names
Protein Families by Multiple Sequences